FF:10836-111D8: Difference between revisions
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{{f5samples | {{f5samples | ||
|ancestors_in_anatomy_facet= | |DRA_sample_Accession=CAGE@SAMD00005980 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |accession_numbers=CAGE;DRX007818;DRR008690;DRZ000115;DRZ001500;DRZ011465;DRZ012850 | ||
| | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000255 | |||
|ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:14566,DOID:0060083,DOID:1240,DOID:8692 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100737,FF:0101035,FF:0101883,FF:0100740 | |||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
|expression_enrichment_score=chr2:239148671..239148686,-!p1@HES6!2.44!960.08!HES6;;chr12:54694758..54694805,-!p1@NFE2!2.28!226.48!NFE2;;chr9:135854091..135854159,+!p1@GFI1B!2.24!174.78!GFI1B;;chr6:135502501..135502546,+!p1@MYB!2.00!116.93!MYB;;chrX:48644984..48645005,+!p1@GATA1!1.98!93.55!GATA1;;chr12:54694807..54694832,-!p3@NFE2!1.97!92.32!NFE2;;chr19:12998003..12998021,-!p1@KLF1!1.91!80.01!KLF1;;chr19:13213511..13213545,-!p2@LYL1!1.74!59.08!LYL1;;chr5:134369905..134369972,-!p1@PITX1!1.63!62.77!PITX1;;chr17:40441354..40441410,+!p2@STAT5A!1.58!36.93!STAT5A;;chr20:50159198..50159299,-!p1@NFATC2!1.52!46.77!NFATC2;;chr3:128206762..128206781,-!p2@GATA2!1.50!183.40!GATA2;;chr19:12203100..12203132,+!p1@ZNF788!1.48!57.85!ZNF788;;chr8:37963466..37963506,+!p3@ASH2L!1.47!35.70!ASH2L;;chr9:135854074..135854089,+!p2@GFI1B!1.47!28.31!GFI1B;;chr19:22193731..22193751,-!p1@ZNF208!1.41!24.62!ZNF208;;chr12:54785074..54785122,-!p2@ZNF385A!1.40!36.93!ZNF385A;;chr3:128212033..128212051,-!p1@GATA2!1.36!22.16!GATA2;;chr9:20382446..20382493,-!p4@MLLT3!1.34!20.92!MLLT3;;chr12:54689532..54689551,-!p4@NFE2!1.34!20.92!NFE2;;chr1:61548069..61548102,+!p3@NFIA!1.31!46.77!NFIA;;chr19:22235279..22235301,+!p1@ZNF257!1.29!34.46!ZNF257;;chr19:12146483..12146546,-!p1@ZNF433!1.27!64.01!ZNF433;;chr3:18486354..18486377,-!p2@SATB1!1.27!22.16!SATB1;;chr6:144385698..144385742,-!p2@PLAGL1!1.26!20.92!PLAGL1;;chr12:54694653..54694672,-!p2@NFE2!1.26!17.23!NFE2;;chr19:12267524..12267564,-!p1@ZNF20,p1@ZNF625!1.23!76.31!ZNF20;;chr11:31832807..31832823,-!p4@PAX6!1.20!14.77!PAX6;;chr10:94449703..94449718,+!p1@HHEX!1.19!55.39!HHEX;;chr19:11959532..11959593,+!p1@ZNF439!1.19!55.39!ZNF439;;chr19:10305581..10305646,-!p1@DNMT1!1.18!478.81!DNMT1;;chr19:12163769..12163798,-!p1@ZNF878!1.18!18.46!ZNF878;;chr19:54024251..54024305,+!p4@ZNF331!1.17!22.16!ZNF331;;chr19:12203069..12203094,+!p2@ZNF788!1.16!19.69!ZNF788;;chr17:38020392..38020477,-!p1@IKZF3!1.16!13.54!IKZF3;;chr1:47697881..47697910,-!p4@TAL1!1.16!13.54!TAL1;;chr11:47400045..47400060,-!p6@SPI1!1.16!13.54!SPI1;;chr2:25475120..25475176,-!p2@DNMT3A!1.14!17.23!DNMT3A;;chr19:11071685..11071798,+!p1@SMARCA4!1.13!352.03!SMARCA4;;chr3:69788576..69788648,+!p1@MITF!1.12!65.24!MITF;;chr5:134369879..134369898,-!p2@PITX1!1.12!12.31!PITX1;;chr11:47399996..47400014,-!p4@SPI1!1.12!12.31!SPI1;;chr19:11998584..11998649,+!p1@ZNF69!1.11!52.93!ZNF69;;chr2:185463247..185463263,+!p1@ZNF804A!1.11!20.92!ZNF804A;;chr19:11925071..11925113,+!p1@ZNF440!1.09!81.24!ZNF440;;chr20:42295713..42295738,+!p2@MYBL2!1.09!66.47!MYBL2;;chr10:94449675..94449694,+!p2@HHEX!1.09!30.77!HHEX;;chr1:61547894..61547968,+!p2@NFIA!1.08!32.00!NFIA;;chr20:31350184..31350200,+!p1@DNMT3B!1.08!23.39!DNMT3B;;chr19:54024313..54024361,+!p7@ZNF331!1.08!11.08!ZNF331;;chr12:54778471..54778528,-!p1@ZNF385A!1.08!11.08!ZNF385A;;chr7:137620684..137620711,-!p4@CREB3L2!1.08!11.08!CREB3L2;;chr10:94449649..94449664,+!p3@HHEX!1.07!16.00!HHEX;;chr6:135502408..135502459,+!p2@MYB!1.06!12.31!MYB;;chr8:145669791..145669834,-!p1@TONSL!1.05!29.54!TONSL;;chr8:128748308..128748324,+!p2@MYC!1.04!275.72!MYC;;chr5:88178983..88179012,-!p1@MEF2C!1.04!78.78!MEF2C;;chr7:50344289..50344323,+!p1@IKZF1!1.04!9.85!IKZF1;;chr19:46800289..46800327,+!p2@HIF3A!1.04!9.85!HIF3A;;chr19:12267577..12267593,-!p3@ZNF625!1.04!9.85!ZNF625;;chr11:31832658..31832681,-!p1@PAX6!1.04!9.85!PAX6;;chr12:54689552..54689574,-!p6@NFE2!1.04!9.85!NFE2;;chr19:11071652..11071682,+!p3@SMARCA4!1.03!34.46!SMARCA4;;chr3:24536253..24536328,-!p1@THRB!1.03!18.46!THRB;;chr7:27135591..27135658,-!p1@HOXA1!1.02!18.46!HOXA1;;chr19:12273866..12273935,+!p1@ZNF136!1.01!83.70!ZNF136;;chr19:11708311..11708332,+!p2@ZNF627!1.00!17.23!ZNF627;;chr12:54785054..54785072,-!p4@ZNF385A!0.98!9.85!ZNF385A;;chr7:50343634..50343717,+!p2@IKZF1!0.98!8.62!IKZF1;;chr19:13213465..13213478,-!p7@LYL1!0.98!8.62!LYL1;;chr19:12035913..12035933,+!p1@ZNF700,p1@ZNF763!0.95!51.70!ZNF700;;chr6:20402102..20402152,+!p1@E2F3!0.95!33.23!E2F3;;chr6:7108179..7108199,+!p4@RREB1!0.94!16.00!RREB1;;chr1:61548118..61548129,+!p9@NFIA!0.94!8.62!NFIA;;chr8:60031682..60031710,-!p2@TOX!0.93!12.31!TOX;;chr1:61548225..61548299,+!p1@NFIA!0.92!99.70!NFIA;;chr7:148581327..148581347,-!p2@EZH2!0.92!25.85!EZH2;;chr7:50344251..50344288,+!p3@IKZF1!0.92!7.39!IKZF1;;chr3:128207349..128207386,-!p3@GATA2!0.92!7.39!GATA2;;chr11:31833719..31833735,-!p15@PAX6!0.92!7.39!PAX6;;chr11:47400032..47400043,-!p5@SPI1!0.92!7.39!SPI1;;chrY:2803415..2803468,+!p1@ZFY!0.92!7.39!ZFY;;chrY:21906594..21906622,-!p1@KDM5D!0.92!7.39!KDM5D;;chr16:88519669..88519726,+!p1@ZFPM1!0.91!67.70!ZFPM1;;chr8:60031619..60031676,-!p1@TOX!0.91!16.00!TOX;;chr19:23299814..23299844,+!p1@ZNF730!0.90!8.62!ZNF730;;chr12:50479109..50479146,+!p2@SMARCD1!0.89!119.39!SMARCD1;;chr19:11708259..11708309,+!p1@ZNF627!0.88!68.93!ZNF627;;chr19:12035878..12035902,+!p2@ZNF700,p2@ZNF763!0.88!16.00!ZNF700;;chrX:131623982..131624011,-!p6@MBNL3!0.88!9.85!MBNL3;;chr19:57183114..57183145,-!p1@ZNF835!0.88!7.39!ZNF835;;chr20:42295745..42295765,+!p1@MYBL2!0.87!110.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| |||
|ffid_belonging_in_development=CL:0000049,CL:0000134 | |||
|fonse_cell_line=FF:0101035 | |fonse_cell_line=FF:0101035 | ||
|fonse_cell_line_closure=FF:0101035 | |fonse_cell_line_closure=FF:0101035 | ||
| Line 34: | Line 41: | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M6%2529%2520cell%2520line%253aF-36E.CNhs13060.10836-111D8.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M6%2529%2520cell%2520line%253aF-36E.CNhs13060.10836-111D8.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M6%2529%2520cell%2520line%253aF-36E.CNhs13060.10836-111D8.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M6%2529%2520cell%2520line%253aF-36E.CNhs13060.10836-111D8.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M6%2529%2520cell%2520line%253aF-36E.CNhs13060.10836-111D8.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10836-111D8 | |id=FF:10836-111D8 | ||
|is_a=EFO:0002091;;FF: | |is_a=EFO:0002091;;FF:0000210;;FF:0101883 | ||
|is_obsolete= | |||
|library_id=CNhs13060 | |||
|library_id_phase_based=2:CNhs13060 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10836 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10836 | |||
|name=acute myeloid leukemia (FAB M6) cell line:F-36E | |name=acute myeloid leukemia (FAB M6) cell line:F-36E | ||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
| Line 41: | Line 60: | ||
|profile_cagescan=,,, | |profile_cagescan=,,, | ||
|profile_hcage=CNhs13060,LSID1000,release012,COMPLETED | |profile_hcage=CNhs13060,LSID1000,release012,COMPLETED | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq=,,, | |profile_srnaseq=,,, | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,-0.160318030086386,0,0.0571779674365556,-0.108166040612142,0,0,0,0,0,0,0,0,0,0,0,0,0,0.195152029581172,0,0,0,0,0,-0.0979578962680575,0,0,-0.132956589778862,0,0,0,0,0,0,0,0,0,0,0,0,0.125856764904439,0,0,0,0,0,0,0,0,-0.0242150211128343,0,0,0,0,0,-0.0393854382831337,0,-0.0969923612426051,0,0,-0.097343627213097,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.129450295772793,0,0,0,-0.102053404249775,-0.211197402695869,0,0,0,0,-0.0980353512377064,0.131170522861699,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.096373593922461,0,0,0,0,0.0866817509026285,0,0,0,0,0,0 | |||
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| |||
|rna_box=111 | |rna_box=111 | ||
|rna_catalog_number= | |rna_catalog_number= | ||
| Line 56: | Line 78: | ||
|rna_weight_ug=32 | |rna_weight_ug=32 | ||
|sample_age=unknown | |sample_age=unknown | ||
|sample_category=cell lines | |||
|sample_cell_catalog=RCB0776 | |sample_cell_catalog=RCB0776 | ||
|sample_cell_line=F-36E | |sample_cell_line=F-36E | ||
| Line 68: | Line 91: | ||
|sample_ethnicity=J | |sample_ethnicity=J | ||
|sample_experimental_condition= | |sample_experimental_condition= | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.83909692986092e-282!GO:0043227;membrane-bound organelle;2.4560158072366e-238!GO:0043231;intracellular membrane-bound organelle;3.58924509402697e-238!GO:0043226;organelle;5.44185487981705e-234!GO:0043229;intracellular organelle;1.8660451134986e-233!GO:0005737;cytoplasm;5.63100670561015e-165!GO:0044422;organelle part;3.05043453280148e-156!GO:0044446;intracellular organelle part;3.54097865655366e-155!GO:0005634;nucleus;9.39986787066913e-123!GO:0044237;cellular metabolic process;2.71982841120291e-122!GO:0044238;primary metabolic process;4.41364069594429e-116!GO:0044444;cytoplasmic part;1.72889539891965e-115!GO:0032991;macromolecular complex;1.41652538003407e-110!GO:0043170;macromolecule metabolic process;1.12815419536892e-107!GO:0030529;ribonucleoprotein complex;1.05889213851772e-94!GO:0044428;nuclear part;1.11478939711749e-92!GO:0043233;organelle lumen;4.39682319193508e-88!GO:0031974;membrane-enclosed lumen;4.39682319193508e-88!GO:0003723;RNA binding;1.27936878397254e-86!GO:0005739;mitochondrion;2.98185274243484e-75!GO:0043283;biopolymer metabolic process;8.84186540945187e-68!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.21801910461831e-66!GO:0010467;gene expression;9.514202420933e-64!GO:0006396;RNA processing;4.65895311498306e-61!GO:0005515;protein binding;1.03755988217942e-58!GO:0031981;nuclear lumen;3.55799192571064e-56!GO:0043234;protein complex;3.21844506523937e-55!GO:0006412;translation;1.03099091512562e-52!GO:0005840;ribosome;7.97664065922523e-52!GO:0006259;DNA metabolic process;3.38107854214919e-51!GO:0044429;mitochondrial part;7.03849538307888e-51!GO:0003676;nucleic acid binding;1.02121778222031e-48!GO:0016071;mRNA metabolic process;2.27294479241773e-48!GO:0019538;protein metabolic process;1.51715588716161e-46!GO:0031967;organelle envelope;1.55656135528712e-45!GO:0031975;envelope;3.48423361816355e-45!GO:0009058;biosynthetic process;1.591640375012e-44!GO:0016043;cellular component organization and biogenesis;3.01390376927696e-44!GO:0003735;structural constituent of ribosome;5.77248738081459e-44!GO:0008380;RNA splicing;1.50789104657912e-43!GO:0009059;macromolecule biosynthetic process;1.7466145783574e-42!GO:0031090;organelle membrane;2.15084248580232e-42!GO:0044249;cellular biosynthetic process;4.22187006070464e-42!GO:0044267;cellular protein metabolic process;2.2470727373682e-41!GO:0044260;cellular macromolecule metabolic process;2.64847393524593e-41!GO:0006397;mRNA processing;2.78439950988955e-41!GO:0033036;macromolecule localization;1.06213287479559e-39!GO:0033279;ribosomal subunit;6.35845469283755e-39!GO:0006996;organelle organization and biogenesis;1.67051974449039e-37!GO:0065003;macromolecular complex assembly;2.45028916794727e-37!GO:0022613;ribonucleoprotein complex biogenesis and assembly;9.0416003074117e-37!GO:0015031;protein transport;9.79009300262227e-37!GO:0043228;non-membrane-bound organelle;9.90245975631066e-36!GO:0043232;intracellular non-membrane-bound organelle;9.90245975631066e-36!GO:0005829;cytosol;1.69144124990096e-35!GO:0005654;nucleoplasm;2.14336811688165e-35!GO:0008104;protein localization;8.87137828615534e-35!GO:0045184;establishment of protein localization;9.77181551646904e-35!GO:0016070;RNA metabolic process;2.54522893982529e-34!GO:0005740;mitochondrial envelope;3.67558458821934e-32!GO:0022607;cellular component assembly;4.83423056321984e-32!GO:0000166;nucleotide binding;5.7721108161892e-32!GO:0005681;spliceosome;1.80509230311678e-31!GO:0019866;organelle inner membrane;9.80976728047996e-31!GO:0007049;cell cycle;4.26226671336829e-30!GO:0031966;mitochondrial membrane;1.17955646230184e-29!GO:0046907;intracellular transport;2.3920371237233e-29!GO:0044451;nucleoplasm part;3.37439795362045e-28!GO:0005743;mitochondrial inner membrane;3.38589823193722e-28!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.94744361699453e-27!GO:0006974;response to DNA damage stimulus;4.08967492257908e-27!GO:0051276;chromosome organization and biogenesis;4.43731907505837e-27!GO:0005694;chromosome;3.26341825506828e-26!GO:0044445;cytosolic part;4.96883415704735e-26!GO:0006281;DNA repair;1.15200116553395e-25!GO:0016462;pyrophosphatase activity;1.51079948245608e-25!GO:0017111;nucleoside-triphosphatase activity;1.98641904796989e-25!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;2.79020065288931e-25!GO:0016817;hydrolase activity, acting on acid anhydrides;4.17189557518388e-25!GO:0006886;intracellular protein transport;1.67501827569671e-24!GO:0044427;chromosomal part;7.33050998449444e-24!GO:0022402;cell cycle process;2.62412775153928e-23!GO:0031980;mitochondrial lumen;3.11478404196395e-23!GO:0005759;mitochondrial matrix;3.11478404196395e-23!GO:0000278;mitotic cell cycle;1.41906173471159e-22!GO:0005730;nucleolus;1.98733023916315e-22!GO:0051649;establishment of cellular localization;1.00996609681315e-21!GO:0032553;ribonucleotide binding;1.27026352759762e-21!GO:0032555;purine ribonucleotide binding;1.27026352759762e-21!GO:0044455;mitochondrial membrane part;1.32730911667087e-21!GO:0006325;establishment and/or maintenance of chromatin architecture;1.38228966988582e-21!GO:0016887;ATPase activity;1.41433835938444e-21!GO:0005524;ATP binding;2.18599415289289e-21!GO:0051641;cellular localization;2.4413037675558e-21!GO:0006119;oxidative phosphorylation;2.9154640978492e-21!GO:0032559;adenyl ribonucleotide binding;3.42584962814354e-21!GO:0022618;protein-RNA complex assembly;4.51813620922447e-21!GO:0017076;purine nucleotide binding;4.84962670697934e-21!GO:0006323;DNA packaging;1.0558371268915e-20!GO:0042623;ATPase activity, coupled;1.13994403526767e-20!GO:0030554;adenyl nucleotide binding;2.92868142721707e-20!GO:0015935;small ribosomal subunit;3.032134104074e-20!GO:0015934;large ribosomal subunit;9.95261073018807e-20!GO:0009719;response to endogenous stimulus;1.30916715471014e-19!GO:0016874;ligase activity;1.64339799922279e-19!GO:0006457;protein folding;5.2664112229162e-19!GO:0006260;DNA replication;5.66577188101235e-19!GO:0044265;cellular macromolecule catabolic process;6.33340029002399e-19!GO:0006512;ubiquitin cycle;7.18938577171971e-19!GO:0022403;cell cycle phase;3.66808633539378e-18!GO:0043285;biopolymer catabolic process;6.35674872248192e-18!GO:0005746;mitochondrial respiratory chain;2.27400706503071e-17!GO:0000087;M phase of mitotic cell cycle;2.35498589397184e-17!GO:0012505;endomembrane system;3.36194666313984e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;6.32899299351693e-17!GO:0006511;ubiquitin-dependent protein catabolic process;7.63222880520316e-17!GO:0007067;mitosis;7.68179320139379e-17!GO:0019941;modification-dependent protein catabolic process;9.44528757389617e-17!GO:0043632;modification-dependent macromolecule catabolic process;9.44528757389617e-17!GO:0008135;translation factor activity, nucleic acid binding;9.75218132294058e-17!GO:0004386;helicase activity;9.94621325756142e-17!GO:0044257;cellular protein catabolic process;1.30097987545127e-16!GO:0016604;nuclear body;1.76667507877597e-16!GO:0051186;cofactor metabolic process;2.39209489366013e-16!GO:0042254;ribosome biogenesis and assembly;2.42164601064119e-16!GO:0044248;cellular catabolic process;2.42209667679899e-16!GO:0009057;macromolecule catabolic process;2.90549775764203e-16!GO:0008134;transcription factor binding;1.98636906319553e-15!GO:0051301;cell division;2.42001120629722e-15!GO:0000398;nuclear mRNA splicing, via spliceosome;2.4992180748479e-15!GO:0000375;RNA splicing, via transesterification reactions;2.4992180748479e-15!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;2.4992180748479e-15!GO:0044453;nuclear membrane part;3.01438306234918e-15!GO:0000279;M phase;3.24581025192002e-15!GO:0051082;unfolded protein binding;3.5493205426942e-15!GO:0050136;NADH dehydrogenase (quinone) activity;3.64950222274032e-15!GO:0003954;NADH dehydrogenase activity;3.64950222274032e-15!GO:0008137;NADH dehydrogenase (ubiquinone) activity;3.64950222274032e-15!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;5.57169568165476e-15!GO:0005761;mitochondrial ribosome;9.94119483155754e-15!GO:0000313;organellar ribosome;9.94119483155754e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.15114435092377e-14!GO:0000502;proteasome complex (sensu Eukaryota);1.57095016225753e-14!GO:0048770;pigment granule;2.21661484348636e-14!GO:0042470;melanosome;2.21661484348636e-14!GO:0005635;nuclear envelope;2.56833901069405e-14!GO:0016568;chromatin modification;2.65420306859292e-14!GO:0000785;chromatin;3.22530533846629e-14!GO:0008026;ATP-dependent helicase activity;3.46968971943648e-14!GO:0006399;tRNA metabolic process;3.70882884398762e-14!GO:0006333;chromatin assembly or disassembly;4.11927990320264e-14!GO:0006605;protein targeting;9.65549266074902e-14!GO:0005643;nuclear pore;1.25482768814535e-13!GO:0030163;protein catabolic process;1.60269339359125e-13!GO:0042775;organelle ATP synthesis coupled electron transport;2.02352679876677e-13!GO:0042773;ATP synthesis coupled electron transport;2.02352679876677e-13!GO:0031965;nuclear membrane;2.10005140241242e-13!GO:0030964;NADH dehydrogenase complex (quinone);2.39900298361206e-13!GO:0045271;respiratory chain complex I;2.39900298361206e-13!GO:0005747;mitochondrial respiratory chain complex I;2.39900298361206e-13!GO:0003743;translation initiation factor activity;3.2018440409684e-13!GO:0050657;nucleic acid transport;3.54710058167181e-13!GO:0051236;establishment of RNA localization;3.54710058167181e-13!GO:0050658;RNA transport;3.54710058167181e-13!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);5.7420242463343e-13!GO:0006403;RNA localization;5.7420242463343e-13!GO:0006413;translational initiation;6.81334162380517e-13!GO:0065004;protein-DNA complex assembly;7.13182853244773e-13!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;7.79803931902398e-13!GO:0043412;biopolymer modification;8.15800326490779e-13!GO:0016607;nuclear speck;1.2430631790882e-12!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.49580901433137e-12!GO:0003712;transcription cofactor activity;6.53635159877276e-12!GO:0006732;coenzyme metabolic process;8.56443279813202e-12!GO:0046930;pore complex;9.34253785621534e-12!GO:0006364;rRNA processing;1.22912946027996e-11!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.26719954909333e-11!GO:0004812;aminoacyl-tRNA ligase activity;1.26719954909333e-11!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.26719954909333e-11!GO:0051028;mRNA transport;2.82934978953973e-11!GO:0043038;amino acid activation;2.82934978953973e-11!GO:0006418;tRNA aminoacylation for protein translation;2.82934978953973e-11!GO:0043039;tRNA aminoacylation;2.82934978953973e-11!GO:0016072;rRNA metabolic process;2.95296935836347e-11!GO:0006913;nucleocytoplasmic transport;3.49038250867699e-11!GO:0006446;regulation of translational initiation;6.27736121650782e-11!GO:0051169;nuclear transport;6.64918579163893e-11!GO:0048193;Golgi vesicle transport;1.28221700173584e-10!GO:0005794;Golgi apparatus;1.40671841559617e-10!GO:0044432;endoplasmic reticulum part;1.55168487223229e-10!GO:0006464;protein modification process;2.08370199650337e-10!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;4.31373262289801e-10!GO:0065002;intracellular protein transport across a membrane;4.37575335762487e-10!GO:0005783;endoplasmic reticulum;4.74172521306076e-10!GO:0051726;regulation of cell cycle;7.32977267530709e-10!GO:0006261;DNA-dependent DNA replication;7.4512804708846e-10!GO:0043687;post-translational protein modification;7.83613138762243e-10!GO:0008565;protein transporter activity;8.0928854028484e-10!GO:0000074;regulation of progression through cell cycle;1.26177773044706e-09!GO:0003697;single-stranded DNA binding;1.31768849839262e-09!GO:0051188;cofactor biosynthetic process;1.40595750963241e-09!GO:0000775;chromosome, pericentric region;1.52575154012945e-09!GO:0043566;structure-specific DNA binding;2.05493347598488e-09!GO:0031497;chromatin assembly;2.07126714938969e-09!GO:0019222;regulation of metabolic process;2.89512605189779e-09!GO:0009056;catabolic process;2.91321678318228e-09!GO:0006334;nucleosome assembly;3.08027802986901e-09!GO:0006461;protein complex assembly;3.62058284781426e-09!GO:0012501;programmed cell death;3.69946854141783e-09!GO:0016779;nucleotidyltransferase activity;3.76348780807877e-09!GO:0030532;small nuclear ribonucleoprotein complex;4.34495852914497e-09!GO:0017038;protein import;5.03601868288153e-09!GO:0006915;apoptosis;6.7997988982209e-09!GO:0050794;regulation of cellular process;6.95524036665875e-09!GO:0005813;centrosome;7.51733333139577e-09!GO:0006163;purine nucleotide metabolic process;7.59359022000041e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;9.52747055946645e-09!GO:0009259;ribonucleotide metabolic process;9.60838742872775e-09!GO:0009055;electron carrier activity;1.42965696034062e-08!GO:0008219;cell death;1.62532103303137e-08!GO:0016265;death;1.62532103303137e-08!GO:0005815;microtubule organizing center;1.68246884431887e-08!GO:0016192;vesicle-mediated transport;1.68851116696953e-08!GO:0006164;purine nucleotide biosynthetic process;2.26335762243732e-08!GO:0015630;microtubule cytoskeleton;2.57481989167677e-08!GO:0016787;hydrolase activity;2.74127620587307e-08!GO:0015078;hydrogen ion transmembrane transporter activity;2.78875546384342e-08!GO:0000245;spliceosome assembly;3.09507681054733e-08!GO:0016740;transferase activity;3.96296826166701e-08!GO:0009260;ribonucleotide biosynthetic process;4.11596505630009e-08!GO:0009150;purine ribonucleotide metabolic process;4.80412814227918e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;5.09823920759054e-08!GO:0019829;cation-transporting ATPase activity;5.34790988149508e-08!GO:0006366;transcription from RNA polymerase II promoter;6.07430640961459e-08!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;6.75239805651553e-08!GO:0031323;regulation of cellular metabolic process;8.36529349690591e-08!GO:0042175;nuclear envelope-endoplasmic reticulum network;9.91769581226907e-08!GO:0008639;small protein conjugating enzyme activity;1.04421825378505e-07!GO:0009152;purine ribonucleotide biosynthetic process;1.4293261506977e-07!GO:0006350;transcription;1.67084062728565e-07!GO:0000075;cell cycle checkpoint;2.08115635198388e-07!GO:0008094;DNA-dependent ATPase activity;2.10093175263165e-07!GO:0016879;ligase activity, forming carbon-nitrogen bonds;2.20378153115965e-07!GO:0015986;ATP synthesis coupled proton transport;2.26392188365989e-07!GO:0015985;energy coupled proton transport, down electrochemical gradient;2.26392188365989e-07!GO:0005789;endoplasmic reticulum membrane;2.26392188365989e-07!GO:0004842;ubiquitin-protein ligase activity;2.37644383841449e-07!GO:0005819;spindle;2.94489025888847e-07!GO:0009060;aerobic respiration;3.31885401837213e-07!GO:0006310;DNA recombination;3.45895207629878e-07!GO:0019787;small conjugating protein ligase activity;4.92176795671015e-07!GO:0003724;RNA helicase activity;6.50420932655738e-07!GO:0015077;monovalent inorganic cation transmembrane transporter activity;6.91518152935885e-07!GO:0009141;nucleoside triphosphate metabolic process;8.03401847954945e-07!GO:0007005;mitochondrion organization and biogenesis;8.5421898752888e-07!GO:0009199;ribonucleoside triphosphate metabolic process;8.74734162481195e-07!GO:0045259;proton-transporting ATP synthase complex;8.89021583891728e-07!GO:0046034;ATP metabolic process;1.10608229847808e-06!GO:0006754;ATP biosynthetic process;1.19946406727295e-06!GO:0006753;nucleoside phosphate metabolic process;1.19946406727295e-06!GO:0009108;coenzyme biosynthetic process;1.20916226320872e-06!GO:0003713;transcription coactivator activity;1.35338433096847e-06!GO:0009142;nucleoside triphosphate biosynthetic process;1.3652797351532e-06!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.3652797351532e-06!GO:0051329;interphase of mitotic cell cycle;1.38791424855964e-06!GO:0003899;DNA-directed RNA polymerase activity;1.5073844231004e-06!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.7078720271023e-06!GO:0009144;purine nucleoside triphosphate metabolic process;1.7078720271023e-06!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.85981076107345e-06!GO:0005667;transcription factor complex;2.05158085807574e-06!GO:0051325;interphase;2.4982204428884e-06!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.78183798926735e-06!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.78183798926735e-06!GO:0010468;regulation of gene expression;2.9794756853394e-06!GO:0016469;proton-transporting two-sector ATPase complex;3.17365319592661e-06!GO:0005793;ER-Golgi intermediate compartment;3.49867639318565e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;4.4470054563716e-06!GO:0045333;cellular respiration;4.61037045619149e-06!GO:0003677;DNA binding;4.93669569081695e-06!GO:0005762;mitochondrial large ribosomal subunit;4.97039543054421e-06!GO:0000315;organellar large ribosomal subunit;4.97039543054421e-06!GO:0005657;replication fork;4.99760110989475e-06!GO:0032446;protein modification by small protein conjugation;5.48434245917974e-06!GO:0016881;acid-amino acid ligase activity;5.60057584070174e-06!GO:0051170;nuclear import;6.71438639952611e-06!GO:0006099;tricarboxylic acid cycle;6.9039666857651e-06!GO:0046356;acetyl-CoA catabolic process;6.9039666857651e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;6.9039666857651e-06!GO:0006084;acetyl-CoA metabolic process;6.94470940763147e-06!GO:0006091;generation of precursor metabolites and energy;7.32587220367773e-06!GO:0006302;double-strand break repair;7.69828854135069e-06!GO:0003684;damaged DNA binding;8.11559145945162e-06!GO:0006606;protein import into nucleus;8.19250411866878e-06!GO:0003682;chromatin binding;8.24119361760748e-06!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;8.39573198376589e-06!GO:0015399;primary active transmembrane transporter activity;8.39573198376589e-06!GO:0044431;Golgi apparatus part;8.49213592247692e-06!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;9.00929136863784e-06!GO:0050789;regulation of biological process;9.00929136863784e-06!GO:0016310;phosphorylation;9.4087619154222e-06!GO:0051246;regulation of protein metabolic process;9.67043633253774e-06!GO:0048475;coated membrane;9.88918815691366e-06!GO:0030117;membrane coat;9.88918815691366e-06!GO:0043623;cellular protein complex assembly;1.06011360088271e-05!GO:0044452;nucleolar part;1.06011360088271e-05!GO:0006793;phosphorus metabolic process;1.09074366011445e-05!GO:0006796;phosphate metabolic process;1.09074366011445e-05!GO:0006888;ER to Golgi vesicle-mediated transport;1.095724651925e-05!GO:0006338;chromatin remodeling;1.12202416881913e-05!GO:0003678;DNA helicase activity;1.1398840146024e-05!GO:0005839;proteasome core complex (sensu Eukaryota);1.14683902066724e-05!GO:0006752;group transfer coenzyme metabolic process;1.16639499760244e-05!GO:0000151;ubiquitin ligase complex;1.18493874408502e-05!GO:0006383;transcription from RNA polymerase III promoter;1.2968632179036e-05!GO:0000776;kinetochore;1.31153979957608e-05!GO:0006082;organic acid metabolic process;1.62223914534128e-05!GO:0032774;RNA biosynthetic process;1.72255278601313e-05!GO:0019752;carboxylic acid metabolic process;1.74042385842745e-05!GO:0016567;protein ubiquitination;1.77216036381734e-05!GO:0003690;double-stranded DNA binding;1.84292440062575e-05!GO:0003714;transcription corepressor activity;1.87055961464446e-05!GO:0009117;nucleotide metabolic process;2.12181220835419e-05!GO:0006351;transcription, DNA-dependent;2.24744730025438e-05!GO:0016491;oxidoreductase activity;2.36197036375382e-05!GO:0043492;ATPase activity, coupled to movement of substances;2.45943830609959e-05!GO:0000786;nucleosome;2.64749064709124e-05!GO:0004527;exonuclease activity;2.64749064709124e-05!GO:0051168;nuclear export;2.72819601611492e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;2.78117778840369e-05!GO:0051187;cofactor catabolic process;3.20754328411394e-05!GO:0006402;mRNA catabolic process;3.28984349044652e-05!GO:0030120;vesicle coat;3.43163580258736e-05!GO:0030662;coated vesicle membrane;3.43163580258736e-05!GO:0008168;methyltransferase activity;3.65008071955785e-05!GO:0016741;transferase activity, transferring one-carbon groups;3.79537139198022e-05!GO:0009109;coenzyme catabolic process;3.88342409107388e-05!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;4.22979195603468e-05!GO:0016563;transcription activator activity;4.22979195603468e-05!GO:0004298;threonine endopeptidase activity;4.56799470002133e-05!GO:0003729;mRNA binding;5.26746338212328e-05!GO:0006401;RNA catabolic process;5.28056934845306e-05!GO:0005768;endosome;5.78660460619259e-05!GO:0008186;RNA-dependent ATPase activity;6.05595137462727e-05!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;6.08609027219365e-05!GO:0007059;chromosome segregation;6.53102872822501e-05!GO:0016363;nuclear matrix;7.69787852318209e-05!GO:0000314;organellar small ribosomal subunit;9.11454872499522e-05!GO:0005763;mitochondrial small ribosomal subunit;9.11454872499522e-05!GO:0007051;spindle organization and biogenesis;9.16398033352686e-05!GO:0043067;regulation of programmed cell death;9.61869269095328e-05!GO:0006352;transcription initiation;9.67218396205415e-05!GO:0043021;ribonucleoprotein binding;0.000105574185977897!GO:0005788;endoplasmic reticulum lumen;0.000106805463464545!GO:0008654;phospholipid biosynthetic process;0.00011487318332748!GO:0042981;regulation of apoptosis;0.000115780334906406!GO:0008033;tRNA processing;0.000131456345221237!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000138066169229213!GO:0006613;cotranslational protein targeting to membrane;0.000145900258313341!GO:0000139;Golgi membrane;0.000164543253406542!GO:0004004;ATP-dependent RNA helicase activity;0.000169497792364417!GO:0007093;mitotic cell cycle checkpoint;0.00018781132576638!GO:0004518;nuclease activity;0.000198427869442282!GO:0006405;RNA export from nucleus;0.000208374042531561!GO:0045449;regulation of transcription;0.000229429241561312!GO:0031072;heat shock protein binding;0.000231347455438758!GO:0000059;protein import into nucleus, docking;0.000268960170282585!GO:0022890;inorganic cation transmembrane transporter activity;0.00027561789922472!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000292319314172215!GO:0046483;heterocycle metabolic process;0.000335083982893088!GO:0019899;enzyme binding;0.000335083982893088!GO:0006520;amino acid metabolic process;0.000336662965478409!GO:0016853;isomerase activity;0.000359425144254776!GO:0009165;nucleotide biosynthetic process;0.000365709155147607!GO:0032508;DNA duplex unwinding;0.000376406620778239!GO:0032392;DNA geometric change;0.000376406620778239!GO:0045454;cell redox homeostasis;0.000404725947679697!GO:0005770;late endosome;0.000449642090431875!GO:0005741;mitochondrial outer membrane;0.000450495296166431!GO:0043681;protein import into mitochondrion;0.0005033841598017!GO:0006268;DNA unwinding during replication;0.000546312557387431!GO:0031968;organelle outer membrane;0.000552148260130878!GO:0005798;Golgi-associated vesicle;0.000556415265416469!GO:0006950;response to stress;0.00057296812014539!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00057296812014539!GO:0005769;early endosome;0.000575623204563129!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000594577638370383!GO:0016564;transcription repressor activity;0.000594577638370383!GO:0019867;outer membrane;0.000639367691563426!GO:0006626;protein targeting to mitochondrion;0.000639367691563426!GO:0000049;tRNA binding;0.00067694571548823!GO:0045786;negative regulation of progression through cell cycle;0.000698377570790883!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.000754262891054759!GO:0030867;rough endoplasmic reticulum membrane;0.000830488346569824!GO:0030880;RNA polymerase complex;0.000871034131323717!GO:0015992;proton transport;0.000881660007824958!GO:0051052;regulation of DNA metabolic process;0.000898168886331178!GO:0006818;hydrogen transport;0.000967259546090832!GO:0006778;porphyrin metabolic process;0.000968827530856331!GO:0033013;tetrapyrrole metabolic process;0.000968827530856331!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.001000977488663!GO:0006270;DNA replication initiation;0.00104327913657835!GO:0007052;mitotic spindle organization and biogenesis;0.0010768242234674!GO:0065007;biological regulation;0.00108174515936978!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00108724136839445!GO:0006779;porphyrin biosynthetic process;0.00112546431397455!GO:0033014;tetrapyrrole biosynthetic process;0.00112546431397455!GO:0046467;membrane lipid biosynthetic process;0.00113984704897747!GO:0051427;hormone receptor binding;0.0011508422436342!GO:0016272;prefoldin complex;0.00115567925655161!GO:0051287;NAD binding;0.00115567925655161!GO:0051920;peroxiredoxin activity;0.00116929754129702!GO:0048523;negative regulation of cellular process;0.0012261052314851!GO:0007006;mitochondrial membrane organization and biogenesis;0.00129820957795082!GO:0006730;one-carbon compound metabolic process;0.00132572647098721!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00133524019581088!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00133524019581088!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00133621957641578!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00133621957641578!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00133621957641578!GO:0005885;Arp2/3 protein complex;0.00138089334171266!GO:0003924;GTPase activity;0.00138127236071749!GO:0015980;energy derivation by oxidation of organic compounds;0.00141830135628311!GO:0031988;membrane-bound vesicle;0.00144315902628551!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00144968573383665!GO:0006612;protein targeting to membrane;0.00147562212565231!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00151521497264585!GO:0000792;heterochromatin;0.0016191226241967!GO:0042168;heme metabolic process;0.00163553912314931!GO:0005637;nuclear inner membrane;0.00170137897759598!GO:0003711;transcription elongation regulator activity;0.00171829588135098!GO:0006783;heme biosynthetic process;0.0017451110767319!GO:0006414;translational elongation;0.00176036659052127!GO:0016859;cis-trans isomerase activity;0.00187065132244388!GO:0006355;regulation of transcription, DNA-dependent;0.00190275520838737!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.00198410771577958!GO:0016023;cytoplasmic membrane-bound vesicle;0.00201889017892134!GO:0048500;signal recognition particle;0.00203440889037506!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00211406530168353!GO:0000428;DNA-directed RNA polymerase complex;0.00211406530168353!GO:0035257;nuclear hormone receptor binding;0.00216242612846461!GO:0005791;rough endoplasmic reticulum;0.00228775384836667!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00229456223500195!GO:0015002;heme-copper terminal oxidase activity;0.00229456223500195!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00229456223500195!GO:0004129;cytochrome-c oxidase activity;0.00229456223500195!GO:0000922;spindle pole;0.00237840040672088!GO:0006284;base-excision repair;0.00238376197812717!GO:0031570;DNA integrity checkpoint;0.00248458160626421!GO:0031982;vesicle;0.00250972007007316!GO:0043069;negative regulation of programmed cell death;0.00260040847855688!GO:0031324;negative regulation of cellular metabolic process;0.00271623104712912!GO:0044440;endosomal part;0.00274421275255667!GO:0010008;endosome membrane;0.00274421275255667!GO:0005669;transcription factor TFIID complex;0.0028580061755837!GO:0004003;ATP-dependent DNA helicase activity;0.00286456416266609!GO:0008632;apoptotic program;0.00298757099804148!GO:0005684;U2-dependent spliceosome;0.00341461336898656!GO:0016584;nucleosome positioning;0.00349982209425!GO:0006839;mitochondrial transport;0.0035793467914263!GO:0051789;response to protein stimulus;0.00360872760622836!GO:0006986;response to unfolded protein;0.00360872760622836!GO:0035258;steroid hormone receptor binding;0.00365145892718165!GO:0032200;telomere organization and biogenesis;0.00371232360693558!GO:0000723;telomere maintenance;0.00371232360693558!GO:0006519;amino acid and derivative metabolic process;0.00381717678197886!GO:0008312;7S RNA binding;0.00381905442114692!GO:0042802;identical protein binding;0.00389737581449186!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00394481752809961!GO:0009303;rRNA transcription;0.00394481752809961!GO:0051087;chaperone binding;0.00395664131339578!GO:0030218;erythrocyte differentiation;0.00402529188026035!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.00420850865276653!GO:0004674;protein serine/threonine kinase activity;0.00427367076426346!GO:0005876;spindle microtubule;0.00429468006662153!GO:0008250;oligosaccharyl transferase complex;0.00429989610995486!GO:0006118;electron transport;0.00430375896386647!GO:0000725;recombinational repair;0.00430375896386647!GO:0000724;double-strand break repair via homologous recombination;0.00430375896386647!GO:0043066;negative regulation of apoptosis;0.00463381946263508!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0047227633569655!GO:0007088;regulation of mitosis;0.00473198336595692!GO:0006916;anti-apoptosis;0.00473339489579571!GO:0050749;apolipoprotein E receptor binding;0.0047600583600396!GO:0009451;RNA modification;0.00484503307886315!GO:0031410;cytoplasmic vesicle;0.00490513173705182!GO:0019843;rRNA binding;0.00502650170050271!GO:0019783;small conjugating protein-specific protease activity;0.0056097375958129!GO:0048037;cofactor binding;0.00566333751874773!GO:0000096;sulfur amino acid metabolic process;0.00579756253129152!GO:0045045;secretory pathway;0.00581253356589146!GO:0016585;chromatin remodeling complex;0.00599360283603361!GO:0042393;histone binding;0.00603369425632729!GO:0030118;clathrin coat;0.006131018316818!GO:0047485;protein N-terminus binding;0.00615512213320841!GO:0006289;nucleotide-excision repair;0.00653506829248262!GO:0008276;protein methyltransferase activity;0.00661020058305016!GO:0031252;leading edge;0.0066296261737686!GO:0008234;cysteine-type peptidase activity;0.00666831534341772!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00685388018497365!GO:0045047;protein targeting to ER;0.00685388018497365!GO:0004843;ubiquitin-specific protease activity;0.00695516617616777!GO:0032259;methylation;0.00698195010099877!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00742413235038255!GO:0008139;nuclear localization sequence binding;0.00748194581198239!GO:0043189;H4/H2A histone acetyltransferase complex;0.00748709721601528!GO:0048471;perinuclear region of cytoplasm;0.00753159470100869!GO:0016251;general RNA polymerase II transcription factor activity;0.00763738963593414!GO:0000123;histone acetyltransferase complex;0.00764355982798036!GO:0040029;regulation of gene expression, epigenetic;0.00769668390689882!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.00769668390689882!GO:0009081;branched chain family amino acid metabolic process;0.00773703933882427!GO:0051252;regulation of RNA metabolic process;0.00790551228781788!GO:0006643;membrane lipid metabolic process;0.00799561662250772!GO:0006406;mRNA export from nucleus;0.00803511051875866!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00830376870579188!GO:0043414;biopolymer methylation;0.00832829790496147!GO:0006144;purine base metabolic process;0.00849480000379626!GO:0005758;mitochondrial intermembrane space;0.0085313499667348!GO:0008610;lipid biosynthetic process;0.00860784422704682!GO:0051540;metal cluster binding;0.00884437138618219!GO:0051536;iron-sulfur cluster binding;0.00884437138618219!GO:0005525;GTP binding;0.00910856013105099!GO:0051053;negative regulation of DNA metabolic process;0.00919211588625848!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00935678613425619!GO:0018196;peptidyl-asparagine modification;0.00935678613425619!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00935678613425619!GO:0048519;negative regulation of biological process;0.00946215668199292!GO:0000819;sister chromatid segregation;0.00956500563826331!GO:0046474;glycerophospholipid biosynthetic process;0.00957581463351436!GO:0015631;tubulin binding;0.00957581463351436!GO:0044450;microtubule organizing center part;0.00957581463351436!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.0100286799331712!GO:0005048;signal sequence binding;0.0100752951568615!GO:0065009;regulation of a molecular function;0.0102792495604382!GO:0016790;thiolester hydrolase activity;0.0103204731279334!GO:0006611;protein export from nucleus;0.0103332684065232!GO:0050662;coenzyme binding;0.0104352611457834!GO:0000077;DNA damage checkpoint;0.0108968254861344!GO:0035267;NuA4 histone acetyltransferase complex;0.011309916060339!GO:0007017;microtubule-based process;0.0114235241553447!GO:0005874;microtubule;0.0114885559290985!GO:0043488;regulation of mRNA stability;0.0116209764217857!GO:0043487;regulation of RNA stability;0.0116209764217857!GO:0004221;ubiquitin thiolesterase activity;0.0117932012481314!GO:0000178;exosome (RNase complex);0.0118870093782993!GO:0031124;mRNA 3'-end processing;0.0119068317559015!GO:0000070;mitotic sister chromatid segregation;0.0119910848001301!GO:0030132;clathrin coat of coated pit;0.0122036490656831!GO:0000082;G1/S transition of mitotic cell cycle;0.0122036490656831!GO:0006595;polyamine metabolic process;0.0122381023001155!GO:0043284;biopolymer biosynthetic process;0.0122391151857415!GO:0008408;3'-5' exonuclease activity;0.0122676505788795!GO:0031970;organelle envelope lumen;0.0122693071532889!GO:0006400;tRNA modification;0.0126604847090727!GO:0043624;cellular protein complex disassembly;0.0127827398979209!GO:0030518;steroid hormone receptor signaling pathway;0.0128082042759399!GO:0008144;drug binding;0.013007293289244!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0134151910071845!GO:0042026;protein refolding;0.0135201068945937!GO:0046519;sphingoid metabolic process;0.0135561526219547!GO:0006417;regulation of translation;0.013689408999562!GO:0009308;amine metabolic process;0.013689408999562!GO:0030663;COPI coated vesicle membrane;0.0138343685961297!GO:0030126;COPI vesicle coat;0.0138343685961297!GO:0030658;transport vesicle membrane;0.0139727928657729!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0140931188357898!GO:0008022;protein C-terminus binding;0.0140931188357898!GO:0005832;chaperonin-containing T-complex;0.0141739418988068!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0144037144984702!GO:0009112;nucleobase metabolic process;0.0144037144984702!GO:0006979;response to oxidative stress;0.0144841465527508!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0147588693142896!GO:0004576;oligosaccharyl transferase activity;0.0148514061683104!GO:0016835;carbon-oxygen lyase activity;0.0149581146085229!GO:0030134;ER to Golgi transport vesicle;0.0151381166193644!GO:0046426;negative regulation of JAK-STAT cascade;0.0151381166193644!GO:0030131;clathrin adaptor complex;0.0151979033560189!GO:0048487;beta-tubulin binding;0.0152965156369157!GO:0030119;AP-type membrane coat adaptor complex;0.0153344561187986!GO:0043596;nuclear replication fork;0.0153395790274894!GO:0006672;ceramide metabolic process;0.015853696322736!GO:0008637;apoptotic mitochondrial changes;0.0159079894404576!GO:0022406;membrane docking;0.0161010107943342!GO:0048278;vesicle docking;0.0161010107943342!GO:0009892;negative regulation of metabolic process;0.0164884207824498!GO:0009066;aspartate family amino acid metabolic process;0.0165342970429108!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.0165537400149213!GO:0030521;androgen receptor signaling pathway;0.0169277707905888!GO:0015036;disulfide oxidoreductase activity;0.0171003640297579!GO:0032984;macromolecular complex disassembly;0.0171774307307635!GO:0000118;histone deacetylase complex;0.0171861717642278!GO:0006376;mRNA splice site selection;0.0175251425442007!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0175251425442007!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0175599427548507!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0175838899607762!GO:0043241;protein complex disassembly;0.0181189407371737!GO:0006650;glycerophospholipid metabolic process;0.0185053328723443!GO:0045815;positive regulation of gene expression, epigenetic;0.0188135100347001!GO:0000339;RNA cap binding;0.0191705238485988!GO:0030176;integral to endoplasmic reticulum membrane;0.0192454371659143!GO:0042770;DNA damage response, signal transduction;0.0192454371659143!GO:0008652;amino acid biosynthetic process;0.0195320321089569!GO:0030660;Golgi-associated vesicle membrane;0.0197736734991918!GO:0006807;nitrogen compound metabolic process;0.0202639696885828!GO:0008180;signalosome;0.0207498869131827!GO:0006415;translational termination;0.0208302052971823!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0210651087951941!GO:0043022;ribosome binding;0.0215860042626508!GO:0000228;nuclear chromosome;0.0215860042626508!GO:0008287;protein serine/threonine phosphatase complex;0.0215976133120979!GO:0006378;mRNA polyadenylation;0.0216600641924649!GO:0031123;RNA 3'-end processing;0.021807848967301!GO:0030508;thiol-disulfide exchange intermediate activity;0.0220792470530915!GO:0008017;microtubule binding;0.022250402016491!GO:0030127;COPII vesicle coat;0.0225518655041055!GO:0012507;ER to Golgi transport vesicle membrane;0.0225518655041055!GO:0006891;intra-Golgi vesicle-mediated transport;0.022791530236674!GO:0046914;transition metal ion binding;0.023405350398841!GO:0000209;protein polyubiquitination;0.0236374044730189!GO:0022411;cellular component disassembly;0.0236654853262365!GO:0016408;C-acyltransferase activity;0.0237068566195337!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0237068566195337!GO:0030496;midbody;0.0237068566195337!GO:0033116;ER-Golgi intermediate compartment membrane;0.0239312590221191!GO:0032940;secretion by cell;0.0239576822703797!GO:0016407;acetyltransferase activity;0.0241636226610891!GO:0003887;DNA-directed DNA polymerase activity;0.024173142864088!GO:0046128;purine ribonucleoside metabolic process;0.0244529573666542!GO:0042278;purine nucleoside metabolic process;0.0244529573666542!GO:0018193;peptidyl-amino acid modification;0.0247725829200259!GO:0016481;negative regulation of transcription;0.025049332554581!GO:0030145;manganese ion binding;0.0250980775048099!GO:0050178;phenylpyruvate tautomerase activity;0.025714004830443!GO:0046489;phosphoinositide biosynthetic process;0.0259350731844752!GO:0031371;ubiquitin conjugating enzyme complex;0.0263469765734233!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.0265095159086574!GO:0044448;cell cortex part;0.0266208222347808!GO:0030384;phosphoinositide metabolic process;0.0266604958884349!GO:0000726;non-recombinational repair;0.0267391006314552!GO:0006607;NLS-bearing substrate import into nucleus;0.0268222053543072!GO:0031577;spindle checkpoint;0.0271420879994188!GO:0042532;negative regulation of tyrosine phosphorylation of STAT protein;0.0273174809501262!GO:0042518;negative regulation of tyrosine phosphorylation of Stat3 protein;0.0273174809501262!GO:0050732;negative regulation of peptidyl-tyrosine phosphorylation;0.0273174809501262!GO:0043601;nuclear replisome;0.0276221536735776!GO:0030894;replisome;0.0276221536735776!GO:0005938;cell cortex;0.0277158643055239!GO:0007021;tubulin folding;0.0284299964865811!GO:0046588;negative regulation of calcium-dependent cell-cell adhesion;0.0284299964865811!GO:0046586;regulation of calcium-dependent cell-cell adhesion;0.0284299964865811!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0289782051528881!GO:0006220;pyrimidine nucleotide metabolic process;0.0290116193675747!GO:0044454;nuclear chromosome part;0.0291098944324708!GO:0000790;nuclear chromatin;0.0291627715418112!GO:0004523;ribonuclease H activity;0.0294325384341622!GO:0000930;gamma-tubulin complex;0.0298730502935759!GO:0032287;myelin maintenance in the peripheral nervous system;0.0301728750058739!GO:0032838;cell projection cytoplasm;0.0301728750058739!GO:0033081;regulation of T cell differentiation in the thymus;0.0301728750058739!GO:0043217;myelin maintenance;0.0301728750058739!GO:0060087;relaxation of vascular smooth muscle;0.0301728750058739!GO:0032839;dendrite cytoplasm;0.0301728750058739!GO:0005528;FK506 binding;0.0301728750058739!GO:0005527;macrolide binding;0.0301728750058739!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0304823270057592!GO:0004532;exoribonuclease activity;0.0304823270057592!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0304823270057592!GO:0030503;regulation of cell redox homeostasis;0.030836026465172!GO:0044262;cellular carbohydrate metabolic process;0.030836026465172!GO:0044438;microbody part;0.030836026465172!GO:0044439;peroxisomal part;0.030836026465172!GO:0007050;cell cycle arrest;0.030836026465172!GO:0006904;vesicle docking during exocytosis;0.031006432442605!GO:0030137;COPI-coated vesicle;0.0313155452453928!GO:0042791;5S class rRNA transcription;0.0313155452453928!GO:0000127;transcription factor TFIIIC complex;0.0313155452453928!GO:0042797;tRNA transcription from RNA polymerase III promoter;0.0313155452453928!GO:0030911;TPR domain binding;0.0313155452453928!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.0313155452453928!GO:0009067;aspartate family amino acid biosynthetic process;0.0314595180628207!GO:0051297;centrosome organization and biogenesis;0.031870088512561!GO:0031023;microtubule organizing center organization and biogenesis;0.031870088512561!GO:0003893;epsilon DNA polymerase activity;0.0327073685017172!GO:0009304;tRNA transcription;0.0330691399959418!GO:0031057;negative regulation of histone modification;0.033355568264491!GO:0035067;negative regulation of histone acetylation;0.033355568264491!GO:0006275;regulation of DNA replication;0.0334150144205152!GO:0031625;ubiquitin protein ligase binding;0.0334150144205152!GO:0000781;chromosome, telomeric region;0.033516292608379!GO:0019079;viral genome replication;0.0335829981855909!GO:0006733;oxidoreduction coenzyme metabolic process;0.0335829981855909!GO:0051101;regulation of DNA binding;0.034122838824726!GO:0005652;nuclear lamina;0.0344934940697348!GO:0007004;telomere maintenance via telomerase;0.0346318483951082!GO:0022415;viral reproductive process;0.0348857027337856!GO:0004239;methionyl aminopeptidase activity;0.0352513895275067!GO:0008286;insulin receptor signaling pathway;0.0358971892640702!GO:0016605;PML body;0.03705560887536!GO:0008270;zinc ion binding;0.0371428316360603!GO:0042054;histone methyltransferase activity;0.0376265085280611!GO:0019904;protein domain specific binding;0.0376485665643691!GO:0031901;early endosome membrane;0.03766723327761!GO:0032561;guanyl ribonucleotide binding;0.0379634171133075!GO:0019001;guanyl nucleotide binding;0.0379634171133075!GO:0006740;NADPH regeneration;0.0392125659036863!GO:0006098;pentose-phosphate shunt;0.0392125659036863!GO:0000152;nuclear ubiquitin ligase complex;0.0392251918814652!GO:0008156;negative regulation of DNA replication;0.039723639966402!GO:0005663;DNA replication factor C complex;0.0401237068307523!GO:0009083;branched chain family amino acid catabolic process;0.0402589313880431!GO:0008159;positive transcription elongation factor activity;0.0402875952848667!GO:0030133;transport vesicle;0.0409462249348904!GO:0000287;magnesium ion binding;0.0421479513150549!GO:0001832;blastocyst growth;0.0430517378260439!GO:0016836;hydro-lyase activity;0.0431724864579343!GO:0006301;postreplication repair;0.0433154669007188!GO:0004448;isocitrate dehydrogenase activity;0.0434628133020268!GO:0051098;regulation of binding;0.0434755670141502!GO:0003747;translation release factor activity;0.0441684671676727!GO:0008079;translation termination factor activity;0.0441684671676727!GO:0005851;eukaryotic translation initiation factor 2B complex;0.0447631377918883!GO:0050681;androgen receptor binding;0.045003802741636!GO:0008629;induction of apoptosis by intracellular signals;0.0454633648734195!GO:0003756;protein disulfide isomerase activity;0.0459095684455235!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0459095684455235!GO:0031903;microbody membrane;0.0460178509304259!GO:0005778;peroxisomal membrane;0.0460178509304259!GO:0000097;sulfur amino acid biosynthetic process;0.0462354723292466!GO:0042769;DNA damage response, detection of DNA damage;0.046360988538683!GO:0031301;integral to organelle membrane;0.0464790061250598!GO:0016197;endosome transport;0.0464851216130287!GO:0005680;anaphase-promoting complex;0.0466607746378454!GO:0044255;cellular lipid metabolic process;0.0473994416861456!GO:0016453;C-acetyltransferase activity;0.0479666927664844!GO:0051539;4 iron, 4 sulfur cluster binding;0.0479666927664844!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.0483208505783961!GO:0003725;double-stranded RNA binding;0.0484478189562873!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0485588929126967!GO:0008538;proteasome activator activity;0.0490947986975856!GO:0035035;histone acetyltransferase binding;0.0496722980901974!GO:0051640;organelle localization;0.0498288367237481 | |||
|sample_id=10836 | |sample_id=10836 | ||
|sample_note= | |sample_note= | ||
| Line 75: | Line 99: | ||
|sample_tissue=blood | |sample_tissue=blood | ||
|top_motifs=GATA6:4.12608792857;RXR{A,B,G}_{NR1H2,PPAR}dimers:2.4613975821;STAT5{A,B}:2.14875817148;HOXA9_MEIS1:1.95263026207;PPARG:1.84869549259;MYB:1.75372174366;POU1F1:1.6572698862;RBPJ:1.51132184901;RORA:1.4472206239;E2F1..5:1.39972612704;POU6F1:1.38485006264;HOX{A4,D4}:1.20516537492;HOX{A6,A7,B6,B7}:1.1383825983;BREu{core}:1.09304982514;POU3F1..4:1.06238496149;CUX2:0.959266753715;POU2F1..3:0.949687866429;NR6A1:0.935693630728;PDX1:0.92105145339;PAX3,7:0.899822339807;NR5A1,2:0.887634487683;SOX{8,9,10}:0.870476651397;ZNF143:0.862243270157;VSX1,2:0.851232987345;HOX{A5,B5}:0.778128746534;NANOG:0.768773302625;NFY{A,B,C}:0.728082327804;IKZF2:0.697620224096;YY1:0.681172953641;PBX1:0.665798528054;FOXQ1:0.662876457327;OCT4_SOX2{dimer}:0.628846786945;FOX{F1,F2,J1}:0.592526959733;ESRRA:0.581328140953;PAX8:0.551178689743;NANOG{mouse}:0.549012111447;AR:0.544589462557;CDX1,2,4:0.515488708015;ZBTB16:0.499945820924;HES1:0.499150047611;PRRX1,2:0.491148205355;bHLH_family:0.474836361381;SPZ1:0.468842269909;NR1H4:0.450859027896;NKX2-1,4:0.437706988904;FOXA2:0.42012652329;T:0.403451606098;STAT1,3:0.396727453568;NRF1:0.383985730489;EN1,2:0.365927306744;NKX2-2,8:0.35584712229;CRX:0.346580034795;SOX17:0.282549651833;NFIX:0.269742386091;TFAP4:0.228168429347;POU5F1:0.225837379171;EVI1:0.22447476387;LEF1_TCF7_TCF7L1,2:0.214752178052;ALX1:0.212646028089;ELK1,4_GABP{A,B1}:0.203415136536;PAX6:0.153661677978;AHR_ARNT_ARNT2:0.150575656524;SMAD1..7,9:0.136256127836;MYOD1:0.133062391741;PITX1..3:0.121149774581;GFI1:0.116581138745;TGIF1:0.0884474432263;TFDP1:0.0734737643046;RUNX1..3:0.0290284809112;HAND1,2:0.0226522985837;LHX3,4:-0.00519845451745;AIRE:-0.00724660170211;BPTF:-0.0190440033021;SPI1:-0.0222817932818;SPIB:-0.0234664425237;SNAI1..3:-0.0456937127045;HNF1A:-0.0845612444501;ZEB1:-0.0913239339199;DBP:-0.102552686257;NFE2:-0.111080303992;ZNF148:-0.119973692277;PAX1,9:-0.126228786582;TOPORS:-0.126832248009;PAX4:-0.136381116275;RREB1:-0.147146206499;ELF1,2,4:-0.147676199861;PAX2:-0.150876980859;HNF4A_NR2F1,2:-0.164672851805;REST:-0.171244234641;FOXD3:-0.172727473482;RXRA_VDR{dimer}:-0.1742920885;ADNP_IRX_SIX_ZHX:-0.186722758947;HLF:-0.198076152995;STAT2,4,6:-0.200569386485;NKX2-3_NKX2-5:-0.217337479932;NHLH1,2:-0.217841719119;KLF4:-0.219306233089;CEBPA,B_DDIT3:-0.222829446975;NR3C1:-0.229493603998;ETS1,2:-0.248160986245;NFKB1_REL_RELA:-0.26018440473;ONECUT1,2:-0.26175582194;RXR{A,B,G}:-0.28822896735;DMAP1_NCOR{1,2}_SMARC:-0.295799380387;CDC5L:-0.319548330238;FOXN1:-0.338679656642;FOX{I1,J2}:-0.340000189837;FOXP3:-0.340819961081;FOSL2:-0.385234250315;IRF7:-0.385635645812;MED-1{core}:-0.409585328471;TBX4,5:-0.410160477122;MEF2{A,B,C,D}:-0.414585584116;SOX5:-0.420907534313;MYBL2:-0.425530414505;ATF4:-0.445419666211;IRF1,2:-0.451530329859;FOS_FOS{B,L1}_JUN{B,D}:-0.452601570011;BACH2:-0.461276739901;NFE2L1:-0.465336167758;NKX3-1:-0.472273020344;ATF5_CREB3:-0.47694953176;EGR1..3:-0.477471526685;FOXP1:-0.498625981336;HSF1,2:-0.508805312452;ZNF238:-0.510629876303;NKX3-2:-0.536719682719;NFE2L2:-0.538458135932;NKX6-1,2:-0.540264577094;MTF1:-0.541141151449;EBF1:-0.552493736208;SREBF1,2:-0.561299641281;TLX2:-0.568009260373;HMGA1,2:-0.576214576515;ZNF384:-0.583964561092;PATZ1:-0.600666924314;SOX2:-0.636034936026;GTF2I:-0.653633351222;HIC1:-0.673128684632;HBP1_HMGB_SSRP1_UBTF:-0.676849786308;GZF1:-0.686720451734;TAL1_TCF{3,4,12}:-0.692890951549;RFX1:-0.704534380686;NFIL3:-0.719228522995;FOX{D1,D2}:-0.726530544445;MZF1:-0.732943978263;MYFfamily:-0.738092843655;TFAP2{A,C}:-0.748876579778;LMO2:-0.755709577537;ZBTB6:-0.761249454324;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.761902306687;TEF:-0.766384517312;TLX1..3_NFIC{dimer}:-0.770988645918;CREB1:-0.781283054464;RFX2..5_RFXANK_RFXAP:-0.782723100752;ESR1:-0.796599119147;UFEwm:-0.838945371802;GCM1,2:-0.851264106227;FOXM1:-0.861888525339;HMX1:-0.88178975269;ZNF423:-0.895274383701;ZFP161:-0.91179384316;GFI1B:-0.949013417151;ATF2:-0.956699193141;MAFB:-0.962304553834;IKZF1:-0.976346698174;TEAD1:-0.977593787608;GATA4:-0.993964483935;TFAP2B:-1.01260849037;NFATC1..3:-1.0139045981;ARID5B:-1.0636658127;FOXO1,3,4:-1.07461319475;ATF6:-1.0774755248;XBP1:-1.08754912331;ZIC1..3:-1.09555279866;TP53:-1.10870562753;MAZ:-1.17149912918;PRDM1:-1.23281604641;PAX5:-1.24402576345;GLI1..3:-1.27000931359;SRF:-1.34033005721;JUN:-1.36810969721;GTF2A1,2:-1.37366478303;ALX4:-1.39849462962;SP1:-1.50230343332;TFCP2:-1.506220805;TBP:-1.53455266505;XCPE1{core}:-1.54105781834;FOXL1:-1.54904593789;MTE{core}:-1.58577607757;EP300:-2.08755102673;HIF1A:-2.13800103744 | |top_motifs=GATA6:4.12608792857;RXR{A,B,G}_{NR1H2,PPAR}dimers:2.4613975821;STAT5{A,B}:2.14875817148;HOXA9_MEIS1:1.95263026207;PPARG:1.84869549259;MYB:1.75372174366;POU1F1:1.6572698862;RBPJ:1.51132184901;RORA:1.4472206239;E2F1..5:1.39972612704;POU6F1:1.38485006264;HOX{A4,D4}:1.20516537492;HOX{A6,A7,B6,B7}:1.1383825983;BREu{core}:1.09304982514;POU3F1..4:1.06238496149;CUX2:0.959266753715;POU2F1..3:0.949687866429;NR6A1:0.935693630728;PDX1:0.92105145339;PAX3,7:0.899822339807;NR5A1,2:0.887634487683;SOX{8,9,10}:0.870476651397;ZNF143:0.862243270157;VSX1,2:0.851232987345;HOX{A5,B5}:0.778128746534;NANOG:0.768773302625;NFY{A,B,C}:0.728082327804;IKZF2:0.697620224096;YY1:0.681172953641;PBX1:0.665798528054;FOXQ1:0.662876457327;OCT4_SOX2{dimer}:0.628846786945;FOX{F1,F2,J1}:0.592526959733;ESRRA:0.581328140953;PAX8:0.551178689743;NANOG{mouse}:0.549012111447;AR:0.544589462557;CDX1,2,4:0.515488708015;ZBTB16:0.499945820924;HES1:0.499150047611;PRRX1,2:0.491148205355;bHLH_family:0.474836361381;SPZ1:0.468842269909;NR1H4:0.450859027896;NKX2-1,4:0.437706988904;FOXA2:0.42012652329;T:0.403451606098;STAT1,3:0.396727453568;NRF1:0.383985730489;EN1,2:0.365927306744;NKX2-2,8:0.35584712229;CRX:0.346580034795;SOX17:0.282549651833;NFIX:0.269742386091;TFAP4:0.228168429347;POU5F1:0.225837379171;EVI1:0.22447476387;LEF1_TCF7_TCF7L1,2:0.214752178052;ALX1:0.212646028089;ELK1,4_GABP{A,B1}:0.203415136536;PAX6:0.153661677978;AHR_ARNT_ARNT2:0.150575656524;SMAD1..7,9:0.136256127836;MYOD1:0.133062391741;PITX1..3:0.121149774581;GFI1:0.116581138745;TGIF1:0.0884474432263;TFDP1:0.0734737643046;RUNX1..3:0.0290284809112;HAND1,2:0.0226522985837;LHX3,4:-0.00519845451745;AIRE:-0.00724660170211;BPTF:-0.0190440033021;SPI1:-0.0222817932818;SPIB:-0.0234664425237;SNAI1..3:-0.0456937127045;HNF1A:-0.0845612444501;ZEB1:-0.0913239339199;DBP:-0.102552686257;NFE2:-0.111080303992;ZNF148:-0.119973692277;PAX1,9:-0.126228786582;TOPORS:-0.126832248009;PAX4:-0.136381116275;RREB1:-0.147146206499;ELF1,2,4:-0.147676199861;PAX2:-0.150876980859;HNF4A_NR2F1,2:-0.164672851805;REST:-0.171244234641;FOXD3:-0.172727473482;RXRA_VDR{dimer}:-0.1742920885;ADNP_IRX_SIX_ZHX:-0.186722758947;HLF:-0.198076152995;STAT2,4,6:-0.200569386485;NKX2-3_NKX2-5:-0.217337479932;NHLH1,2:-0.217841719119;KLF4:-0.219306233089;CEBPA,B_DDIT3:-0.222829446975;NR3C1:-0.229493603998;ETS1,2:-0.248160986245;NFKB1_REL_RELA:-0.26018440473;ONECUT1,2:-0.26175582194;RXR{A,B,G}:-0.28822896735;DMAP1_NCOR{1,2}_SMARC:-0.295799380387;CDC5L:-0.319548330238;FOXN1:-0.338679656642;FOX{I1,J2}:-0.340000189837;FOXP3:-0.340819961081;FOSL2:-0.385234250315;IRF7:-0.385635645812;MED-1{core}:-0.409585328471;TBX4,5:-0.410160477122;MEF2{A,B,C,D}:-0.414585584116;SOX5:-0.420907534313;MYBL2:-0.425530414505;ATF4:-0.445419666211;IRF1,2:-0.451530329859;FOS_FOS{B,L1}_JUN{B,D}:-0.452601570011;BACH2:-0.461276739901;NFE2L1:-0.465336167758;NKX3-1:-0.472273020344;ATF5_CREB3:-0.47694953176;EGR1..3:-0.477471526685;FOXP1:-0.498625981336;HSF1,2:-0.508805312452;ZNF238:-0.510629876303;NKX3-2:-0.536719682719;NFE2L2:-0.538458135932;NKX6-1,2:-0.540264577094;MTF1:-0.541141151449;EBF1:-0.552493736208;SREBF1,2:-0.561299641281;TLX2:-0.568009260373;HMGA1,2:-0.576214576515;ZNF384:-0.583964561092;PATZ1:-0.600666924314;SOX2:-0.636034936026;GTF2I:-0.653633351222;HIC1:-0.673128684632;HBP1_HMGB_SSRP1_UBTF:-0.676849786308;GZF1:-0.686720451734;TAL1_TCF{3,4,12}:-0.692890951549;RFX1:-0.704534380686;NFIL3:-0.719228522995;FOX{D1,D2}:-0.726530544445;MZF1:-0.732943978263;MYFfamily:-0.738092843655;TFAP2{A,C}:-0.748876579778;LMO2:-0.755709577537;ZBTB6:-0.761249454324;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.761902306687;TEF:-0.766384517312;TLX1..3_NFIC{dimer}:-0.770988645918;CREB1:-0.781283054464;RFX2..5_RFXANK_RFXAP:-0.782723100752;ESR1:-0.796599119147;UFEwm:-0.838945371802;GCM1,2:-0.851264106227;FOXM1:-0.861888525339;HMX1:-0.88178975269;ZNF423:-0.895274383701;ZFP161:-0.91179384316;GFI1B:-0.949013417151;ATF2:-0.956699193141;MAFB:-0.962304553834;IKZF1:-0.976346698174;TEAD1:-0.977593787608;GATA4:-0.993964483935;TFAP2B:-1.01260849037;NFATC1..3:-1.0139045981;ARID5B:-1.0636658127;FOXO1,3,4:-1.07461319475;ATF6:-1.0774755248;XBP1:-1.08754912331;ZIC1..3:-1.09555279866;TP53:-1.10870562753;MAZ:-1.17149912918;PRDM1:-1.23281604641;PAX5:-1.24402576345;GLI1..3:-1.27000931359;SRF:-1.34033005721;JUN:-1.36810969721;GTF2A1,2:-1.37366478303;ALX4:-1.39849462962;SP1:-1.50230343332;TFCP2:-1.506220805;TBP:-1.53455266505;XCPE1{core}:-1.54105781834;FOXL1:-1.54904593789;MTE{core}:-1.58577607757;EP300:-2.08755102673;HIF1A:-2.13800103744 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10836-111D8;search_select_hide=table117:FF:10836-111D8 | |||
}} | }} | ||
Latest revision as of 15:08, 3 June 2020
| Name: | acute myeloid leukemia (FAB M6) cell line:F-36E |
|---|---|
| Species: | Human (Homo sapiens) |
| Library ID: | CNhs13060 |
| Sample type: | cell lines |
| Genomic View: | UCSC |
| RefEX: | Specific genes |
| CAGEd-oPOSSUM: | link |
| ZENBU report : | link |
| Additional information | ||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sample information
RNA information
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| CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| Download raw sequence, BAM & CTSS | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13060
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13060
| Novel motif | Logo | P-value |
|---|---|---|
| 1 | 1 | 0.00577 |
| 10 | 10 | 0.0606 |
| 100 | 100 | 0.642 |
| 101 | 101 | 0.637 |
| 102 | 102 | 0.286 |
| 103 | 103 | 0.0201 |
| 104 | 104 | 0.992 |
| 105 | 105 | 0.305 |
| 106 | 106 | 0.612 |
| 107 | 107 | 0.554 |
| 108 | 108 | 0.723 |
| 109 | 109 | 0.0537 |
| 11 | 11 | 0.0928 |
| 110 | 110 | 0.156 |
| 111 | 111 | 0.0447 |
| 112 | 112 | 0.837 |
| 113 | 113 | 0.63 |
| 114 | 114 | 0.0176 |
| 115 | 115 | 0.0189 |
| 116 | 116 | 0.344 |
| 117 | 117 | 0.0599 |
| 118 | 118 | 0.835 |
| 119 | 119 | 0.74 |
| 12 | 12 | 0.836 |
| 120 | 120 | 0.793 |
| 121 | 121 | 0.724 |
| 122 | 122 | 0.351 |
| 123 | 123 | 0.0617 |
| 124 | 124 | 0.0375 |
| 125 | 125 | 0.724 |
| 126 | 126 | 0.195 |
| 127 | 127 | 0.15 |
| 128 | 128 | 0.66 |
| 129 | 129 | 0.117 |
| 13 | 13 | 0.0753 |
| 130 | 130 | 0.171 |
| 131 | 131 | 0.972 |
| 132 | 132 | 0.163 |
| 133 | 133 | 0.0024 |
| 134 | 134 | 0.885 |
| 135 | 135 | 0.742 |
| 136 | 136 | 0.757 |
| 137 | 137 | 0.834 |
| 138 | 138 | 0.899 |
| 139 | 139 | 0.039 |
| 14 | 14 | 0.945 |
| 140 | 140 | 0.151 |
| 141 | 141 | 0.0265 |
| 142 | 142 | 0.819 |
| 143 | 143 | 0.818 |
| 144 | 144 | 0.951 |
| 145 | 145 | 0.943 |
| 146 | 146 | 0.922 |
| 147 | 147 | 0.225 |
| 148 | 148 | 0.102 |
| 149 | 149 | 0.182 |
| 15 | 15 | 0.0655 |
| 150 | 150 | 0.889 |
| 151 | 151 | 0.721 |
| 152 | 152 | 0.152 |
| 153 | 153 | 0.276 |
| 154 | 154 | 0.872 |
| 155 | 155 | 0.0778 |
| 156 | 156 | 0.575 |
| 157 | 157 | 0.601 |
| 158 | 158 | 0.0683 |
| 159 | 159 | 0.479 |
| 16 | 16 | 0.594 |
| 160 | 160 | 0.102 |
| 161 | 161 | 0.0508 |
| 162 | 162 | 0.968 |
| 163 | 163 | 0.663 |
| 164 | 164 | 0.78 |
| 165 | 165 | 0.583 |
| 166 | 166 | 0.312 |
| 167 | 167 | 0.0272 |
| 168 | 168 | 0.972 |
| 169 | 169 | 0.834 |
| 17 | 17 | 0.144 |
| 18 | 18 | 0.152 |
| 19 | 19 | 0.78 |
| 2 | 2 | 0.432 |
| 20 | 20 | 0.818 |
| 21 | 21 | 0.548 |
| 22 | 22 | 0.674 |
| 23 | 23 | 0.679 |
| 24 | 24 | 0.609 |
| 25 | 25 | 0.27 |
| 26 | 26 | 0.0575 |
| 27 | 27 | 0.989 |
| 28 | 28 | 0.539 |
| 29 | 29 | 0.0881 |
| 3 | 3 | 0.288 |
| 30 | 30 | 0.204 |
| 31 | 31 | 0.797 |
| 32 | 32 | 0.335 |
| 33 | 33 | 0.872 |
| 34 | 34 | 0.958 |
| 35 | 35 | 0.0942 |
| 36 | 36 | 0.0304 |
| 37 | 37 | 0.465 |
| 38 | 38 | 0.662 |
| 39 | 39 | 0.622 |
| 4 | 4 | 0.202 |
| 40 | 40 | 0.379 |
| 41 | 41 | 0.441 |
| 42 | 42 | 0.235 |
| 43 | 43 | 0.256 |
| 44 | 44 | 0.844 |
| 45 | 45 | 0.743 |
| 46 | 46 | 0.0623 |
| 47 | 47 | 0.0513 |
| 48 | 48 | 0.468 |
| 49 | 49 | 0.0338 |
| 5 | 5 | 0.154 |
| 50 | 50 | 0.666 |
| 51 | 51 | 0.304 |
| 52 | 52 | 0.659 |
| 53 | 53 | 0.709 |
| 54 | 54 | 0.85 |
| 55 | 55 | 0.762 |
| 56 | 56 | 0.493 |
| 57 | 57 | 0.0937 |
| 58 | 58 | 0.219 |
| 59 | 59 | 0.637 |
| 6 | 6 | 0.976 |
| 60 | 60 | 0.746 |
| 61 | 61 | 0.439 |
| 62 | 62 | 0.064 |
| 63 | 63 | 0.841 |
| 64 | 64 | 0.134 |
| 65 | 65 | 0.851 |
| 66 | 66 | 0.0202 |
| 67 | 67 | 0.844 |
| 68 | 68 | 0.352 |
| 69 | 69 | 0.328 |
| 7 | 7 | 0.101 |
| 70 | 70 | 0.66 |
| 71 | 71 | 0.091 |
| 72 | 72 | 0.934 |
| 73 | 73 | 0.575 |
| 74 | 74 | 0.0947 |
| 75 | 75 | 0.0237 |
| 76 | 76 | 0.704 |
| 77 | 77 | 0.876 |
| 78 | 78 | 0.0196 |
| 79 | 79 | 0.0973 |
| 8 | 8 | 0.0865 |
| 80 | 80 | 0.698 |
| 81 | 81 | 0.463 |
| 82 | 82 | 0.551 |
| 83 | 83 | 0.221 |
| 84 | 84 | 0.198 |
| 85 | 85 | 0.933 |
| 86 | 86 | 0.89 |
| 87 | 87 | 0.93 |
| 88 | 88 | 0.949 |
| 89 | 89 | 0.459 |
| 9 | 9 | 0.695 |
| 90 | 90 | 0.0127 |
| 91 | 91 | 0.5 |
| 92 | 92 | 0.832 |
| 93 | 93 | 0.263 |
| 94 | 94 | 0.049 |
| 95 | 95 | 0.288 |
| 96 | 96 | 0.369 |
| 97 | 97 | 0.923 |
| 98 | 98 | 0.0629 |
| 99 | 99 | 0.426 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13060
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0101883 acute myeloid leukemia cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
1240 (leukemia)
8692 (myeloid leukemia)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100737 (leukemia cell line sample)
0101035 (hematopoietic cell line sample)
0101883 (acute myeloid leukemia cell line sample)
0100740 (myeloid leukemia cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)
