FF:10837-111D9: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00004812 | ||
| | |accession_numbers=CAGE;DRX007819;DRR008691;DRZ000116;DRZ001501;DRZ011466;DRZ012851 | ||
| | |ancestors_in_anatomy_facet= | ||
| | |ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000255 | ||
| | |ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:14566,DOID:0060083,DOID:1240,DOID:8692 | ||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100737,FF:0101035,FF:0101883,FF:0100740 | |||
| | |comment= | ||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
| | |datafreeze_phase=2 | ||
| | |def= | ||
| | |expression_enrichment_score=chrX:48644984..48645005,+!p1@GATA1!2.27!183.64!GATA1;;chr3:128212033..128212051,-!p1@GATA2!2.11!128.74!GATA2;;chr2:68592406..68592424,+!p1@PLEK!2.09!123.33!PLEK;;chr19:13213511..13213545,-!p2@LYL1!1.95!95.20!LYL1;;chr9:135854091..135854159,+!p1@GFI1B!1.93!84.65!GFI1B;;chr12:54694758..54694805,-!p1@NFE2!1.88!89.52!NFE2;;chr19:12998003..12998021,-!p1@KLF1!1.82!64.64!KLF1;;chr17:46703687..46703740,-!p1@HOXB9!1.75!55.17!HOXB9;;chr6:135502501..135502546,+!p1@MYB!1.72!60.85!MYB;;chr1:47695003..47695042,-!p2@TAL1!1.62!40.30!TAL1;;chr19:12203100..12203132,+!p1@ZNF788!1.60!77.35!ZNF788;;chr2:68592394..68592405,+!p2@PLEK!1.60!38.40!PLEK;;chr19:22235279..22235301,+!p1@ZNF257!1.56!65.18!ZNF257;;chr12:54694807..54694832,-!p3@NFE2!1.55!34.89!NFE2;;chr19:22193731..22193751,-!p1@ZNF208!1.54!33.81!ZNF208;;chr2:172949484..172949522,+!p1@DLX1!1.51!31.37!DLX1;;chr3:128206762..128206781,-!p2@GATA2!1.46!167.41!GATA2;;chr12:54785074..54785122,-!p2@ZNF385A!1.46!42.46!ZNF385A;;chr8:37963466..37963506,+!p3@ASH2L!1.45!33.54!ASH2L;;chr12:54785054..54785072,-!p4@ZNF385A!1.43!29.21!ZNF385A;;chr5:134369905..134369972,-!p1@PITX1!1.42!38.13!PITX1;;chr1:92949331..92949377,-!p2@GFI1!1.42!25.15!GFI1;;chr2:219849012..219849065,-!p1@FEV!1.40!24.34!FEV;;chr11:47399947..47399961,-!p3@SPI1!1.38!22.99!SPI1;;chr12:54689532..54689551,-!p4@NFE2!1.37!22.18!NFE2;;chr20:31350184..31350200,+!p1@DNMT3B!1.36!44.63!DNMT3B;;chr17:40441354..40441410,+!p2@STAT5A!1.35!21.37!STAT5A;;chr21:36421535..36421610,-!p2@RUNX1!1.32!68.97!RUNX1;;chr1:47697881..47697910,-!p4@TAL1!1.32!20.01!TAL1;;chr6:135502408..135502459,+!p2@MYB!1.27!20.28!MYB;;chr1:47691303..47691319,-!p5@TAL1!1.27!17.58!TAL1;;chr19:11959532..11959593,+!p1@ZNF439!1.24!62.48!ZNF439;;chr11:47400045..47400060,-!p6@SPI1!1.24!16.23!SPI1;;chr1:92951607..92951661,-!p1@GFI1!1.22!15.69!GFI1;;chr19:12267524..12267564,-!p1@ZNF20,p1@ZNF625!1.21!74.10!ZNF20;;chr19:22817119..22817145,+!p1@ZNF492!1.20!24.61!ZNF492;;chr7:63505799..63505904,+!p1@ZNF727!1.20!14.88!ZNF727;;chr19:22605097..22605121,-!p2@ZNF98!1.19!14.33!ZNF98;;chr7:50344289..50344323,+!p1@IKZF1!1.18!14.06!IKZF1;;chrX:48644976..48644983,+!p2@GATA1!1.18!14.06!GATA1;;chr11:113930425..113930471,+!p1@ZBTB16!1.15!18.93!ZBTB16;;chr11:47399996..47400014,-!p4@SPI1!1.15!13.25!SPI1;;chr12:54778471..54778528,-!p1@ZNF385A!1.15!12.98!ZNF385A;;chr19:13213555..13213568,-!p5@LYL1!1.15!12.98!LYL1;;chr11:113930291..113930339,+!p2@ZBTB16!1.14!21.10!ZBTB16;;chr6:126240442..126240459,+!p4@NCOA7!1.10!14.88!NCOA7;;chr11:47400078..47400106,-!p1@SPI1!1.09!11.36!SPI1;;chr11:128563948..128564003,+!p1@FLI1!1.08!133.33!FLI1;;chr20:61051039..61051057,-!p1@GATA5!1.08!11.09!GATA5;;chr19:12035913..12035933,+!p1@ZNF700,p1@ZNF763!1.07!70.05!ZNF700;;chr8:128748308..128748324,+!p2@MYC!1.06!293.17!MYC;;chr19:24097706..24097731,+!p2@ZNF726!1.06!20.28!ZNF726;;chr19:12203069..12203094,+!p2@ZNF788!1.06!15.69!ZNF788;;chr6:126240463..126240489,+!p6@NCOA7!1.05!11.63!NCOA7;;chr13:79177703..79177729,-!p2@POU4F1!1.05!10.28!POU4F1;;chr19:22605136..22605154,-!p1@ZNF98!1.04!10.01!ZNF98;;chr19:11071685..11071798,+!p1@SMARCA4!1.03!279.38!SMARCA4;;chr1:45805872..45805900,+!p2@TOE1!1.03!23.80!TOE1;;chr1:47697539..47697573,-!p3@TAL1!1.03!9.74!TAL1;;chr9:20382446..20382493,-!p4@MLLT3!1.02!9.47!MLLT3;;chr5:88178983..88179012,-!p1@MEF2C!1.01!72.75!MEF2C;;chr19:12163769..12163798,-!p1@ZNF878!1.01!12.17!ZNF878;;chr2:16080659..16080685,+!p1@MYCN!1.01!9.20!MYCN;;chr19:12273866..12273935,+!p1@ZNF136!1.00!83.03!ZNF136;;chr19:11925071..11925113,+!p1@ZNF440!1.00!66.26!ZNF440;;chr12:54689552..54689574,-!p6@NFE2!1.00!8.93!NFE2;;chr5:88179017..88179046,-!p2@MEF2C!0.99!36.24!MEF2C;;chr5:134369879..134369898,-!p2@PITX1!0.98!8.65!PITX1;;chr2:219849897..219849928,-!p2@FEV!0.98!8.65!FEV;;chrY:2803415..2803468,+!p1@ZFY!0.98!8.65!ZFY;;chr20:50159198..50159299,-!p1@NFATC2!0.97!12.44!NFATC2;;chr19:57183114..57183145,-!p1@ZNF835!0.97!9.47!ZNF835;;chr6:15401104..15401166,+!p5@JARID2!0.97!8.38!JARID2;;chr19:11998584..11998649,+!p1@ZNF69!0.96!37.05!ZNF69;;chr10:124895472..124895508,+!p1@HMX3!0.96!8.11!HMX3;;chr19:12146483..12146546,-!p1@ZNF433!0.95!30.02!ZNF433;;chr6:126240380..126240430,+!p2@NCOA7!0.95!21.10!NCOA7;;chr19:23299814..23299844,+!p1@ZNF730!0.95!9.74!ZNF730;;chr6:135502472..135502489,+!p3@MYB!0.95!7.84!MYB;;chr20:42295713..42295738,+!p2@MYBL2!0.94!47.33!MYBL2;;chr6:144385698..144385742,-!p2@PLAGL1!0.94!9.47!PLAGL1;;chr7:115670804..115670825,-!p1@TFEC!0.93!7.57!TFEC;;chr1:47696918..47696935,-!p6@TAL1!0.93!7.57!TAL1;;chr20:42295745..42295765,+!p1@MYBL2!0.92!125.76!MYBL2;;chr19:23433144..23433204,-!p1@ZNF724P!0.92!33.81!ZNF724P;;chr2:219849175..219849187,-!p4@FEV!0.92!7.30!FEV;;chr14:74226961..74227020,-!p1@C14orf43!0.91!48.95!C14orf43;;chr9:135854074..135854089,+!p2@GFI1B!0.90!7.03!GFI1B;;chr19:22193706..22193717,-!p2@ZNF208!0.90!7.03!ZNF208;;chr17:42295777..42295816,-!p7@UBTF!0.89!8.38!UBTF;;chr11:47400032..47400043,-!p5@SPI1!0.89!6.76!SPI1;;chr13:95364784..95364806,-!p1@SOX21!0.89!6.76!SOX21;;chr19: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| ||
| | |ffid_belonging_in_development=CL:0000049,CL:0000134 | ||
| | |||
| | |||
| | |||
|fonse_cell_line=FF:0101035 | |fonse_cell_line=FF:0101035 | ||
|fonse_cell_line_closure=FF:0101035 | |fonse_cell_line_closure=FF:0101035 | ||
Line 66: | Line 40: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M6%2529%2520cell%2520line%253aF-36P.CNhs13505.10837-111D9.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M6%2529%2520cell%2520line%253aF-36P.CNhs13505.10837-111D9.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M6%2529%2520cell%2520line%253aF-36P.CNhs13505.10837-111D9.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M6%2529%2520cell%2520line%253aF-36P.CNhs13505.10837-111D9.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M6%2529%2520cell%2520line%253aF-36P.CNhs13505.10837-111D9.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10837-111D9 | |||
|is_a=EFO:0002091;;FF:0000210;;FF:0101883 | |||
|is_obsolete= | |||
|library_id=CNhs13505 | |||
|library_id_phase_based=2:CNhs13505 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10837 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10837 | |||
|name=acute myeloid leukemia (FAB M6) cell line:F-36P | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs13505,LSID1025,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,-0.160318030086386,0,-0.0168268383336369,0.184156746795466,0,0,0,0,0,0,0,0,0,0,0,0.103959518714163,0,-0.153323010348428,0,0,0,0,0,-0.0979578962680575,0,0,0.328420327929056,0,0,0,0,0,0,0.555295694328555,0,0,0,0,0,-0.0939199576089317,0,0,0,0,0,0,0,0,0.027764738244247,0,0,0,0,0,-0.0442810476473271,0.103959518714163,0.161014098629849,0,0,0.160662832659357,0,0,0,0,0,0,0,0,0.103959518714163,0,0,0,0,0.103959518714163,0,0,0,0,0,0,0.0178185289249513,0,0,-0.00311625393695802,-0.098357471833036,0.185744359620334,0,0,-0.25014772248362,0.182839312660842,0.0519797593570815,0,0.0938888280243945,0.103959518714163,0.00592416747645624,0.145890927293728,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0443938345653797,0.103959518714163,0,0,0,-0.142328520491872,0,0,0.103959518714163,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0.103959518714163,0.00592416747645624,0,0.103959518714163,0.103959518714163,0.187777656048789,0,0.371488719240667,0,0.461376917707919,0,0,0,-0.247178875285564,0,-0.474086218752008,-0.143515142523472,0,0,-0.241534727289237,0,0,0,0.0055787870227128,0,0,0,0.103959518714163,0,-0.024160348238402,0,-0.0504125515893149,0,0,0,0,-0.0186252810838506,-0.117694574849619,0,-0.0452548312132829,-0.0683442610773682,0,0,0,0,-0.0892576800410163,0,-0.120879483793741,-0.0827201683234173,-0.117652069388644,-0.268428600153813,0.0482470219329807,0,0,0,-0.390345074468922,-0.449642657203642,0,0,-0.121779851751874,-0.181349618560659,0,0,-0.391044581551635,0,-0.36555900617234,-0.248868050382253,0,0.211141979616767,0,0,0,0,0,0,0,0,0,0,0,-0.0574934668214365,0.0445001225616985,0,0,0,0,-0.570896988990562,0,0,-0.373286155956567,0.207497644463758,-0.075223753572382,-0.197688771915172,0,-0.198430208295751,0.0135571502810954,-0.383807249598986,-0.25014772248362,-0.147401849371139,-0.189981719549847,0,-0.215516618428868,-0.217536372924766,0.123245478060329,-0.147712753957896,-0.0282326746904208,-0.859919789046437,-0.369704451272582,0,0,0,-0.446700044604474,0,0,0.0100730886119924,-0.401147054918482,-0.433263317498297,-0.40335962044176,0.0215544524815816,0.287297857715248,-0.0395325284566706,-0.199429993024141,-0.0602659021090338,-0.4215723249037,0,1.23621824293073,-0.0877514257027229,-0.120943786160569,-0.059405698375694,0.606537240864448,0,-0.380017943096818,0.39303265663055,0,-0.564422080065633,0.00888115975110537,0,0,-0.117400313163493,0,0,0.131668681463452,0,0,0.089319612945971,-0.435532624316004,-0.0450779055067561,0,-0.055081493932045,0,0.0546533188657765,0,-0.1400658749614,-0.0982112428966428,0.0427484371318558,0.168743113111683,0,0.17363524170487,0.145324493254903,-0.145922346276645,0.365678625321684,-0.0584468268118252,0.0942765228240037,-0.0283735221111103,-0.273751149018366,-0.220203608600981,0.00259490418152392,0.0158326862388749,-0.210162025788965,-0.88354475051838,0.738013054812967,-0.0946019098095964,0.344242054287511,0,-0.116450755533903,0,0.11397368057532,0,0.0666440373071231,-0.436474232759077,-0.0205351165540878,-0.0340841740210605,0,-0.0965764483666048,-0.788130937773974,0,-0.0846067171231917,-0.0164716176863073,0.103959518714163,-0.150367083334639,-0.098357471833036,-0.0238727718158005,-0.0870096973221133,0,-0.602302502340868,0,0,-0.230234494127074,0.0829677048685662,0.103959518714163,0.0665599189581917,0.0946758842233297,-0.0354797850060486,0.14203538643752,0.318443742632955,0,-0.387693878120271,0,0,-0.287484321185075,-0.0636048451378017,0.0349632831758,-0.253326341486756,-0.0971397771337665,-0.108622809454255,0,0,-0.073568247251013,0.187777656048789,0.068059381487206,0,0,0.04978795074095,0,0,0,0,-0.0879092555637855,0,0,0,0,0,0,0,0.182347069756953,-0.0363895875834931,0.187777656048789,-0.0850452907415549,0,0,0,0,0,-0.129406115216345,0,0,-0.619937006915669,-0.169993997089081,-0.12301741567642,0,0,0.0519797593570815,0,0.042283057318979,-0.203236562094724,0,0.329514211210287,0,0,0,0,0.0178185289249513,0,0,0.0519797593570815,0,0.20027600281879,0.0789495083057959,0,0,0,0.291781854587456,0,0,0,0,-0.011507434405462,0,0,-0.19941327127528,0,-0.0820335086766242,-0.0815818795468414,0,0.0354406782884725,-0.362977025957446,-0.108904901895812,0,0,0.0570966108430673,0,0,0.245555615037966,0,0,0,0,0,0,0,0.258006459872454,0,-0.214314512399756,0,0,0,0,0,0,0,0,0,0,0,-0.423347060129869,0.0955535993902783,0,0,0,0,0,0,0,-0.0241060230789031,0.19650150465066,0,0,0,0,0,0.103959518714163,0,0,-0.0100490219553234,0,0,0.103959518714163,0,0,0.161014098629849,0,0,0,0,0.368313493590932,0,0,-0.0193556723210604,0,0,0,0,0,0,0,0,0,0,0,0,0,0.134687373837006,0.0824761110186936,0,0.103959518714163,0,0,0,0,0,-0.0168268383336369,0,0,0,0,1.86684367592935,0,0,0,-0.104796384789156,0,-0.160318030086386,0,0,0.62792558625308,0.0519797593570815,0,0.0918182486752018,0.129003229936227,0.0519797593570815,0,0,0,0,0,0,0,0,0,0,0.209377129013299,0,0,-0.208208919099621,0,-0.316122637786975,-0.0167462595209903,0,0,-0.232628352633041,0,0,0,0,0,0,-0.031340424028527,0,0,0,0,0,0,0,0.0519797593570815,0,0,0,0,0,0,0,0,0,0,0.103959518714163,0,0,0,0,0,0,-0.0093881681278335,0,0,0,0,0,0,0,-0.0979578962680575,0,0,-0.0920328098005262,0,0,0,0,0.103959518714163,0,-0.158973610720482,-0.179260881108984,-0.0548677059830257,0,0,0,-0.054385572482455,0,0,-0.0513473031306939,0.103959518714163,-0.0667773874189013,0,0,0,0,0,0,0,0,0.103959518714163,0,0,0.159221871316477,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.153323010348428,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.180982989293308,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0699481554387463,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0519797593570815,0,0,0,0,0,0.0239410504455243,0,0,0,-0.025308573608255,0,0,0,0,0,0,0.103959518714163,0,0,0,0,0,0.0335864650559671,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.274578262688821,0,0,0,0,0,0,0,0,0,0,0,0,1.11059138865711,0.139555580809734,0,0.0195828864841355,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.788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| |||
|rna_box=111 | |||
|rna_catalog_number= | |||
|rna_concentration=0.43 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=1.72 | |||
|rna_od260/280=1.98 | |||
|rna_position=D9 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=111D9 | |||
|rna_weight_ug=5.2 | |||
|sample_age=65 | |||
|sample_category=cell lines | |||
|sample_cell_catalog=RCB0775 | |||
|sample_cell_line=F-36P | |||
|sample_cell_lot= | |||
|sample_cell_type=erythroblast | |||
|sample_collaboration=Yukio Nakamura (RIKEN BRC) | |||
|sample_company=RIKEN Bioresource centre | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=acute myeloid leukemia (FAB M6) | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=J | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;7.55008721838208e-288!GO:0043227;membrane-bound organelle;4.60394045954606e-254!GO:0043231;intracellular membrane-bound organelle;2.48250560984325e-253!GO:0043226;organelle;3.42122956574693e-244!GO:0043229;intracellular organelle;2.52846717435486e-243!GO:0005737;cytoplasm;1.48501440772263e-162!GO:0044422;organelle part;9.47189998871636e-159!GO:0044446;intracellular organelle part;7.20458612780435e-157!GO:0005634;nucleus;5.67904067367115e-133!GO:0044237;cellular metabolic process;2.18849219348057e-129!GO:0044238;primary metabolic process;2.30715768285179e-124!GO:0032991;macromolecular complex;6.01800789370129e-123!GO:0044444;cytoplasmic part;4.82286038732938e-120!GO:0043170;macromolecule metabolic process;3.28429819877561e-119!GO:0030529;ribonucleoprotein complex;3.94581721624799e-103!GO:0044428;nuclear part;1.21419789863181e-97!GO:0043233;organelle lumen;1.73815458423542e-95!GO:0031974;membrane-enclosed lumen;1.73815458423542e-95!GO:0003723;RNA binding;9.76828236911901e-91!GO:0005739;mitochondrion;5.84508576511158e-84!GO:0043283;biopolymer metabolic process;2.4834435571505e-80!GO:0010467;gene expression;1.86526211549269e-75!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.21819312549859e-74!GO:0006396;RNA processing;8.50254383996942e-65!GO:0043234;protein complex;2.26404891687188e-62!GO:0006412;translation;1.28196558058738e-61!GO:0031981;nuclear lumen;6.51402801464764e-61!GO:0005840;ribosome;5.63537214452159e-59!GO:0044429;mitochondrial part;4.86452624121972e-56!GO:0003676;nucleic acid binding;1.48762711125233e-55!GO:0005515;protein binding;3.5664968246231e-54!GO:0003735;structural constituent of ribosome;1.43910082456701e-51!GO:0019538;protein metabolic process;8.96079861320734e-50!GO:0009058;biosynthetic process;2.79886977249235e-49!GO:0044249;cellular biosynthetic process;4.24189761134888e-49!GO:0031967;organelle envelope;1.15182521175191e-48!GO:0031975;envelope;2.04908567536107e-48!GO:0016071;mRNA metabolic process;3.91200836328908e-48!GO:0009059;macromolecule biosynthetic process;1.36190209852293e-46!GO:0006259;DNA metabolic process;1.57176988196082e-46!GO:0044267;cellular protein metabolic process;1.75141261567608e-45!GO:0044260;cellular macromolecule metabolic process;4.7287317426848e-45!GO:0033279;ribosomal subunit;7.53654588268131e-45!GO:0031090;organelle membrane;1.76117395682888e-44!GO:0016043;cellular component organization and biogenesis;4.03555004510469e-44!GO:0008380;RNA splicing;9.12898904029112e-44!GO:0006397;mRNA processing;2.43223583819556e-42!GO:0033036;macromolecule localization;1.02002941845675e-41!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.12192199176452e-41!GO:0016070;RNA metabolic process;1.81131187760147e-40!GO:0015031;protein transport;2.87936586049711e-40!GO:0065003;macromolecular complex assembly;3.54805793612629e-40!GO:0006996;organelle organization and biogenesis;5.42384428017595e-39!GO:0005829;cytosol;5.53240983508092e-39!GO:0045184;establishment of protein localization;2.92431713264572e-37!GO:0005654;nucleoplasm;3.30225328936581e-37!GO:0008104;protein localization;5.01709393504423e-37!GO:0043228;non-membrane-bound organelle;8.52489097996872e-36!GO:0043232;intracellular non-membrane-bound organelle;8.52489097996872e-36!GO:0022607;cellular component assembly;1.35927145851302e-35!GO:0005740;mitochondrial envelope;1.3850358319983e-34!GO:0019866;organelle inner membrane;1.65340559965093e-33!GO:0005681;spliceosome;1.57811936167324e-32!GO:0007049;cell cycle;3.29898464735325e-32!GO:0046907;intracellular transport;3.87823295104603e-32!GO:0031966;mitochondrial membrane;4.10207961228484e-32!GO:0005743;mitochondrial inner membrane;2.42527678720326e-31!GO:0000166;nucleotide binding;4.61971286194691e-31!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.45816936741976e-30!GO:0044445;cytosolic part;2.03397479698232e-30!GO:0044451;nucleoplasm part;7.78899093373611e-29!GO:0006886;intracellular protein transport;4.82485878375358e-28!GO:0006974;response to DNA damage stimulus;2.77986263670695e-27!GO:0022402;cell cycle process;1.72684331731598e-26!GO:0005694;chromosome;4.32165104773547e-26!GO:0031980;mitochondrial lumen;9.65009729553702e-26!GO:0005759;mitochondrial matrix;9.65009729553702e-26!GO:0051649;establishment of cellular localization;1.99814651179437e-25!GO:0005730;nucleolus;2.38466599114576e-25!GO:0006281;DNA repair;9.92522576954039e-25!GO:0051641;cellular localization;1.69282702003399e-24!GO:0044455;mitochondrial membrane part;2.0209921733676e-24!GO:0006119;oxidative phosphorylation;5.6152007552593e-24!GO:0044427;chromosomal part;8.26666910494395e-24!GO:0015935;small ribosomal subunit;8.89908632222577e-24!GO:0016462;pyrophosphatase activity;1.02732245202056e-23!GO:0000278;mitotic cell cycle;1.09559185240341e-23!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.7237428055837e-23!GO:0016817;hydrolase activity, acting on acid anhydrides;2.38879974677651e-23!GO:0017111;nucleoside-triphosphatase activity;5.92688772947895e-23!GO:0022618;protein-RNA complex assembly;1.312765341048e-22!GO:0015934;large ribosomal subunit;4.5530571232827e-22!GO:0051276;chromosome organization and biogenesis;5.5303040591395e-22!GO:0032553;ribonucleotide binding;6.93664079604881e-22!GO:0032555;purine ribonucleotide binding;6.93664079604881e-22!GO:0005524;ATP binding;4.71712302220468e-21!GO:0017076;purine nucleotide binding;5.2737114567149e-21!GO:0032559;adenyl ribonucleotide binding;1.04036256570147e-20!GO:0022403;cell cycle phase;1.16649178332859e-20!GO:0016874;ligase activity;1.66646165677009e-20!GO:0006457;protein folding;1.38280959416973e-19!GO:0044265;cellular macromolecule catabolic process;1.43428370983691e-19!GO:0030554;adenyl nucleotide binding;1.50134035845696e-19!GO:0005746;mitochondrial respiratory chain;2.32643528591931e-19!GO:0042254;ribosome biogenesis and assembly;2.5191904133545e-19!GO:0000087;M phase of mitotic cell cycle;4.72921636007618e-19!GO:0008135;translation factor activity, nucleic acid binding;5.44157118408882e-19!GO:0007067;mitosis;1.280662460819e-18!GO:0009719;response to endogenous stimulus;1.70705893867166e-18!GO:0006512;ubiquitin cycle;2.2077717736075e-18!GO:0006325;establishment and/or maintenance of chromatin architecture;4.46728430422974e-18!GO:0006260;DNA replication;9.26063789113428e-18!GO:0005761;mitochondrial ribosome;1.04695153856428e-17!GO:0000313;organellar ribosome;1.04695153856428e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;1.7939778927281e-17!GO:0006323;DNA packaging;2.07311617433972e-17!GO:0019941;modification-dependent protein catabolic process;2.07311617433972e-17!GO:0043632;modification-dependent macromolecule catabolic process;2.07311617433972e-17!GO:0000502;proteasome complex (sensu Eukaryota);2.85201852676169e-17!GO:0051186;cofactor metabolic process;3.22755022319916e-17!GO:0000279;M phase;3.31470553424536e-17!GO:0044257;cellular protein catabolic process;3.43386204376899e-17!GO:0006511;ubiquitin-dependent protein catabolic process;3.43386204376899e-17!GO:0044248;cellular catabolic process;3.67803210913849e-17!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;3.82409828664551e-17!GO:0016604;nuclear body;4.07970042612431e-17!GO:0016887;ATPase activity;4.08194419964615e-17!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);4.37557548590151e-17!GO:0050136;NADH dehydrogenase (quinone) activity;6.18942972893837e-17!GO:0003954;NADH dehydrogenase activity;6.18942972893837e-17!GO:0008137;NADH dehydrogenase (ubiquinone) activity;6.18942972893837e-17!GO:0012505;endomembrane system;1.67529998033113e-16!GO:0000398;nuclear mRNA splicing, via spliceosome;1.97207190474254e-16!GO:0000375;RNA splicing, via transesterification reactions;1.97207190474254e-16!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.97207190474254e-16!GO:0043285;biopolymer catabolic process;4.03459991542053e-16!GO:0042623;ATPase activity, coupled;4.58179031546718e-16!GO:0051301;cell division;5.08195814731332e-16!GO:0003743;translation initiation factor activity;9.04936053472004e-16!GO:0043412;biopolymer modification;1.25891300415419e-15!GO:0006605;protein targeting;1.31278643260469e-15!GO:0009057;macromolecule catabolic process;1.56944167506365e-15!GO:0065004;protein-DNA complex assembly;2.93796976719942e-15!GO:0042775;organelle ATP synthesis coupled electron transport;5.60236783367836e-15!GO:0042773;ATP synthesis coupled electron transport;5.60236783367836e-15!GO:0030964;NADH dehydrogenase complex (quinone);6.37605492361895e-15!GO:0045271;respiratory chain complex I;6.37605492361895e-15!GO:0005747;mitochondrial respiratory chain complex I;6.37605492361895e-15!GO:0006413;translational initiation;6.84124348256729e-15!GO:0005635;nuclear envelope;1.23518531988354e-14!GO:0044453;nuclear membrane part;1.31598555425234e-14!GO:0000785;chromatin;1.79691428971697e-14!GO:0006399;tRNA metabolic process;2.28646173614557e-14!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;2.33988203542983e-14!GO:0006333;chromatin assembly or disassembly;2.87676905548959e-14!GO:0004386;helicase activity;3.11917487023901e-14!GO:0031965;nuclear membrane;4.07875205137005e-14!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);4.64904762738286e-14!GO:0051082;unfolded protein binding;4.64904762738286e-14!GO:0048770;pigment granule;6.32630553488852e-14!GO:0042470;melanosome;6.32630553488852e-14!GO:0050657;nucleic acid transport;8.37077416519237e-14!GO:0051236;establishment of RNA localization;8.37077416519237e-14!GO:0050658;RNA transport;8.37077416519237e-14!GO:0006403;RNA localization;9.12965806245224e-14!GO:0006732;coenzyme metabolic process;9.12965806245224e-14!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.18475387765549e-13!GO:0006364;rRNA processing;1.20503195060776e-13!GO:0008134;transcription factor binding;1.5312417378263e-13!GO:0016607;nuclear speck;1.74204371757094e-13!GO:0016072;rRNA metabolic process;1.8266738286222e-13!GO:0051726;regulation of cell cycle;2.1627626370639e-13!GO:0000074;regulation of progression through cell cycle;2.80042134127212e-13!GO:0006464;protein modification process;3.20944134332751e-13!GO:0005643;nuclear pore;3.95778038936693e-13!GO:0050794;regulation of cellular process;7.38145257020203e-13!GO:0030163;protein catabolic process;9.63974916971591e-13!GO:0019222;regulation of metabolic process;1.15833424973544e-12!GO:0065002;intracellular protein transport across a membrane;1.22976276996276e-12!GO:0008026;ATP-dependent helicase activity;2.89208298262839e-12!GO:0051028;mRNA transport;7.65335757619301e-12!GO:0043687;post-translational protein modification;7.89435244217659e-12!GO:0006913;nucleocytoplasmic transport;9.6047353772086e-12!GO:0006334;nucleosome assembly;1.3832495527523e-11!GO:0046930;pore complex;1.3976548486604e-11!GO:0044432;endoplasmic reticulum part;1.47026965407122e-11!GO:0051169;nuclear transport;1.49530628295983e-11!GO:0006446;regulation of translational initiation;1.54006614449068e-11!GO:0016192;vesicle-mediated transport;1.80565325591405e-11!GO:0031497;chromatin assembly;2.08100273249948e-11!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;4.31396607541269e-11!GO:0005783;endoplasmic reticulum;5.2821565797546e-11!GO:0009259;ribonucleotide metabolic process;5.74560820122526e-11!GO:0006163;purine nucleotide metabolic process;1.13068159954346e-10!GO:0009260;ribonucleotide biosynthetic process;1.26413017034829e-10!GO:0006164;purine nucleotide biosynthetic process;1.31846751080997e-10!GO:0016779;nucleotidyltransferase activity;1.48231656568432e-10!GO:0031323;regulation of cellular metabolic process;1.76091591341125e-10!GO:0016568;chromatin modification;1.83941442507893e-10!GO:0051188;cofactor biosynthetic process;2.84635631349966e-10!GO:0048193;Golgi vesicle transport;3.05702185212059e-10!GO:0017038;protein import;3.06858175074307e-10!GO:0008565;protein transporter activity;3.45576855772299e-10!GO:0006350;transcription;3.76842549305818e-10!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;5.42567740512543e-10!GO:0004812;aminoacyl-tRNA ligase activity;5.42567740512543e-10!GO:0016875;ligase activity, forming carbon-oxygen bonds;5.42567740512543e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;5.97969672052889e-10!GO:0030532;small nuclear ribonucleoprotein complex;6.58034489563908e-10!GO:0006366;transcription from RNA polymerase II promoter;1.00694913650842e-09!GO:0009060;aerobic respiration;1.07194506393671e-09!GO:0009150;purine ribonucleotide metabolic process;1.13145315176556e-09!GO:0003712;transcription cofactor activity;1.23601830596881e-09!GO:0043038;amino acid activation;1.27725462893026e-09!GO:0006418;tRNA aminoacylation for protein translation;1.27725462893026e-09!GO:0043039;tRNA aminoacylation;1.27725462893026e-09!GO:0009152;purine ribonucleotide biosynthetic process;1.33410229497121e-09!GO:0012501;programmed cell death;1.97037921344065e-09!GO:0006915;apoptosis;2.4658655503404e-09!GO:0006461;protein complex assembly;2.76942265942913e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;3.91794911023134e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;4.08414049967354e-09!GO:0009056;catabolic process;4.49012115362473e-09!GO:0019829;cation-transporting ATPase activity;4.49012115362473e-09!GO:0003697;single-stranded DNA binding;4.92902047645366e-09!GO:0000775;chromosome, pericentric region;5.09964173823647e-09!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;5.44392171482709e-09!GO:0042175;nuclear envelope-endoplasmic reticulum network;6.6901532079561e-09!GO:0010468;regulation of gene expression;6.76736808966739e-09!GO:0009055;electron carrier activity;7.30477656612244e-09!GO:0016740;transferase activity;8.45796334706343e-09!GO:0008639;small protein conjugating enzyme activity;1.02981150840969e-08!GO:0007005;mitochondrion organization and biogenesis;1.08590411980462e-08!GO:0045333;cellular respiration;1.22758383713358e-08!GO:0005789;endoplasmic reticulum membrane;1.45002881458022e-08!GO:0050789;regulation of biological process;1.52273761748316e-08!GO:0006261;DNA-dependent DNA replication;1.61181268755713e-08!GO:0043566;structure-specific DNA binding;1.86742496686784e-08!GO:0015986;ATP synthesis coupled proton transport;1.93725388089515e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.93725388089515e-08!GO:0003677;DNA binding;2.44983884855642e-08!GO:0004842;ubiquitin-protein ligase activity;3.10257844331447e-08!GO:0008219;cell death;3.44443417043929e-08!GO:0016265;death;3.44443417043929e-08!GO:0009142;nucleoside triphosphate biosynthetic process;3.66199335203462e-08!GO:0009201;ribonucleoside triphosphate biosynthetic process;3.66199335203462e-08!GO:0032774;RNA biosynthetic process;3.83398676483053e-08!GO:0019787;small conjugating protein ligase activity;4.51564482203847e-08!GO:0005793;ER-Golgi intermediate compartment;4.64271645493897e-08!GO:0006084;acetyl-CoA metabolic process;4.82153747416168e-08!GO:0006793;phosphorus metabolic process;5.07619508029687e-08!GO:0006796;phosphate metabolic process;5.07619508029687e-08!GO:0006351;transcription, DNA-dependent;5.60377310708455e-08!GO:0006099;tricarboxylic acid cycle;6.1093538317491e-08!GO:0046356;acetyl-CoA catabolic process;6.1093538317491e-08!GO:0009108;coenzyme biosynthetic process;6.72471336497371e-08!GO:0009199;ribonucleoside triphosphate metabolic process;6.75507209039632e-08!GO:0015078;hydrogen ion transmembrane transporter activity;6.79050538969409e-08!GO:0009141;nucleoside triphosphate metabolic process;6.79050538969409e-08!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;7.90507874782964e-08!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;9.83614922527027e-08!GO:0009145;purine nucleoside triphosphate biosynthetic process;9.83614922527027e-08!GO:0016310;phosphorylation;9.97775700156851e-08!GO:0005839;proteasome core complex (sensu Eukaryota);1.18945294512258e-07!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.6199814734876e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.72861945184978e-07!GO:0009144;purine nucleoside triphosphate metabolic process;1.72861945184978e-07!GO:0016881;acid-amino acid ligase activity;2.00332837990194e-07!GO:0016787;hydrolase activity;2.31295555004917e-07!GO:0006754;ATP biosynthetic process;2.38078177451941e-07!GO:0006753;nucleoside phosphate metabolic process;2.38078177451941e-07!GO:0006752;group transfer coenzyme metabolic process;2.42998782174311e-07!GO:0045259;proton-transporting ATP synthase complex;2.50929713560136e-07!GO:0000245;spliceosome assembly;2.88214383265382e-07!GO:0051246;regulation of protein metabolic process;2.93621886959564e-07!GO:0008094;DNA-dependent ATPase activity;2.98781664058331e-07!GO:0005819;spindle;3.13212602937898e-07!GO:0000786;nucleosome;3.63148850297869e-07!GO:0005794;Golgi apparatus;4.04651632285528e-07!GO:0032446;protein modification by small protein conjugation;5.24975860607262e-07!GO:0016469;proton-transporting two-sector ATPase complex;5.61666643658275e-07!GO:0051329;interphase of mitotic cell cycle;5.72176379166691e-07!GO:0051325;interphase;5.89919673192404e-07!GO:0046034;ATP metabolic process;6.07386279636428e-07!GO:0044452;nucleolar part;6.51547349739143e-07!GO:0003899;DNA-directed RNA polymerase activity;7.59963630817721e-07!GO:0005762;mitochondrial large ribosomal subunit;7.61926718943799e-07!GO:0000315;organellar large ribosomal subunit;7.61926718943799e-07!GO:0007051;spindle organization and biogenesis;8.04948234408122e-07!GO:0009109;coenzyme catabolic process;8.13432712545224e-07!GO:0004298;threonine endopeptidase activity;8.30016237406836e-07!GO:0016567;protein ubiquitination;9.20160338566616e-07!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.33902634402854e-06!GO:0005667;transcription factor complex;1.40033328088257e-06!GO:0051187;cofactor catabolic process;1.85542319455171e-06!GO:0045449;regulation of transcription;2.07684421476045e-06!GO:0000075;cell cycle checkpoint;2.14780747692287e-06!GO:0005657;replication fork;2.19540082448363e-06!GO:0003724;RNA helicase activity;2.31486347836713e-06!GO:0006606;protein import into nucleus;2.5828487565556e-06!GO:0051170;nuclear import;3.05746989362779e-06!GO:0009117;nucleotide metabolic process;3.13230130943414e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;3.20619565425402e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;3.73089630822633e-06!GO:0015630;microtubule cytoskeleton;3.8059775219032e-06!GO:0008033;tRNA processing;5.13792317515041e-06!GO:0003678;DNA helicase activity;6.60978071090062e-06!GO:0005852;eukaryotic translation initiation factor 3 complex;8.33158660419171e-06!GO:0051168;nuclear export;9.39481203858972e-06!GO:0006888;ER to Golgi vesicle-mediated transport;1.0356524686143e-05!GO:0006302;double-strand break repair;1.13631981212827e-05!GO:0005768;endosome;1.23154218771047e-05!GO:0065007;biological regulation;1.23784074173589e-05!GO:0043681;protein import into mitochondrion;1.29472039060551e-05!GO:0000151;ubiquitin ligase complex;1.35575905048155e-05!GO:0006613;cotranslational protein targeting to membrane;1.35575905048155e-05!GO:0000314;organellar small ribosomal subunit;1.46359679484663e-05!GO:0005763;mitochondrial small ribosomal subunit;1.46359679484663e-05!GO:0048475;coated membrane;1.47262377738872e-05!GO:0030117;membrane coat;1.47262377738872e-05!GO:0016491;oxidoreductase activity;1.56567887120078e-05!GO:0005813;centrosome;1.89920031543519e-05!GO:0008654;phospholipid biosynthetic process;2.0673999593601e-05!GO:0016853;isomerase activity;2.13187997101642e-05!GO:0006355;regulation of transcription, DNA-dependent;2.14845989940504e-05!GO:0006091;generation of precursor metabolites and energy;2.20820378366646e-05!GO:0003713;transcription coactivator activity;2.25411533285074e-05!GO:0048523;negative regulation of cellular process;2.54817170771282e-05!GO:0043623;cellular protein complex assembly;2.64878868873611e-05!GO:0006626;protein targeting to mitochondrion;2.75070239245961e-05!GO:0045786;negative regulation of progression through cell cycle;3.18946715972725e-05!GO:0043021;ribonucleoprotein binding;3.59878101131399e-05!GO:0005815;microtubule organizing center;3.84465812007832e-05!GO:0000776;kinetochore;3.99225973852476e-05!GO:0007088;regulation of mitosis;3.99877037742557e-05!GO:0006310;DNA recombination;4.15033834343241e-05!GO:0007059;chromosome segregation;4.17596847004725e-05!GO:0019843;rRNA binding;4.20416467829594e-05!GO:0003690;double-stranded DNA binding;5.30599674566412e-05!GO:0006839;mitochondrial transport;5.37124198116408e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;6.17967068742504e-05!GO:0015399;primary active transmembrane transporter activity;6.17967068742504e-05!GO:0006082;organic acid metabolic process;6.57070060976492e-05!GO:0016363;nuclear matrix;6.71551263424607e-05!GO:0019752;carboxylic acid metabolic process;6.75703890427805e-05!GO:0030880;RNA polymerase complex;6.94477117798747e-05!GO:0004527;exonuclease activity;7.89656580606071e-05!GO:0003924;GTPase activity;8.04345504607777e-05!GO:0022890;inorganic cation transmembrane transporter activity;8.07507554670377e-05!GO:0009165;nucleotide biosynthetic process;8.20937391518833e-05!GO:0051427;hormone receptor binding;8.29176566752059e-05!GO:0003684;damaged DNA binding;8.40678404132309e-05!GO:0006383;transcription from RNA polymerase III promoter;9.21454548111284e-05!GO:0000049;tRNA binding;9.93453570012159e-05!GO:0006612;protein targeting to membrane;0.000101032920285718!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000101032920285718!GO:0008270;zinc ion binding;0.000104694805025683!GO:0007006;mitochondrial membrane organization and biogenesis;0.000108785581590716!GO:0045454;cell redox homeostasis;0.000111430371735029!GO:0016563;transcription activator activity;0.000111430371735029!GO:0030120;vesicle coat;0.000118405396387201!GO:0030662;coated vesicle membrane;0.000118405396387201!GO:0006950;response to stress;0.000128229231182808!GO:0008186;RNA-dependent ATPase activity;0.000128364461038069!GO:0042981;regulation of apoptosis;0.000132274676801618!GO:0016741;transferase activity, transferring one-carbon groups;0.000138319922209665!GO:0006402;mRNA catabolic process;0.000142405472125149!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000142874686959214!GO:0043067;regulation of programmed cell death;0.000145350148453751!GO:0003729;mRNA binding;0.000156699146717561!GO:0031324;negative regulation of cellular metabolic process;0.000161779842172627!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000164247268617769!GO:0008168;methyltransferase activity;0.000164620139154555!GO:0046914;transition metal ion binding;0.000165000874884649!GO:0035257;nuclear hormone receptor binding;0.000170151587273166!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000171335256830099!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.000173964729990145!GO:0000428;DNA-directed RNA polymerase complex;0.000173964729990145!GO:0006414;translational elongation;0.000174733981133457!GO:0006401;RNA catabolic process;0.000177221290936535!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000190221114829327!GO:0006352;transcription initiation;0.000198226046257971!GO:0006405;RNA export from nucleus;0.000223291787579677!GO:0006818;hydrogen transport;0.00023178059542559!GO:0045045;secretory pathway;0.000232948308123884!GO:0016859;cis-trans isomerase activity;0.00023739309198774!GO:0015992;proton transport;0.00024510297762317!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000247605329815568!GO:0048519;negative regulation of biological process;0.000264485809639468!GO:0000059;protein import into nucleus, docking;0.000281942671030218!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000281942671030218!GO:0006520;amino acid metabolic process;0.000305596081410806!GO:0019899;enzyme binding;0.000333850932621543!GO:0005885;Arp2/3 protein complex;0.000339345576557762!GO:0031988;membrane-bound vesicle;0.000339733337055989!GO:0046483;heterocycle metabolic process;0.000340959559948166!GO:0031982;vesicle;0.000356893315021593!GO:0005788;endoplasmic reticulum lumen;0.00036139230267402!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00036191958774793!GO:0004004;ATP-dependent RNA helicase activity;0.000372107966445114!GO:0003682;chromatin binding;0.000382106579423586!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.000418345904800923!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000472755373296398!GO:0007093;mitotic cell cycle checkpoint;0.000478745007357658!GO:0051087;chaperone binding;0.000479937504878711!GO:0015980;energy derivation by oxidation of organic compounds;0.000485913074494999!GO:0051540;metal cluster binding;0.000495022897895838!GO:0051536;iron-sulfur cluster binding;0.000495022897895838!GO:0004518;nuclease activity;0.000545708393934467!GO:0005758;mitochondrial intermembrane space;0.00055256480763085!GO:0051052;regulation of DNA metabolic process;0.000610895439321927!GO:0003714;transcription corepressor activity;0.000618385383956317!GO:0005684;U2-dependent spliceosome;0.00063625278854613!GO:0005525;GTP binding;0.000656161986739914!GO:0051920;peroxiredoxin activity;0.000713226458494554!GO:0007052;mitotic spindle organization and biogenesis;0.000751237751887842!GO:0008610;lipid biosynthetic process;0.000760303022888881!GO:0016564;transcription repressor activity;0.000767883644507103!GO:0030867;rough endoplasmic reticulum membrane;0.000787634914620439!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.000796400702039296!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.000796400702039296!GO:0044440;endosomal part;0.000805767008071397!GO:0010008;endosome membrane;0.000805767008071397!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.0008203321974242!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.0008203321974242!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.0008203321974242!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.000823573073947021!GO:0047485;protein N-terminus binding;0.000841517813498396!GO:0016023;cytoplasmic membrane-bound vesicle;0.000891206962938258!GO:0009451;RNA modification;0.000920450760065602!GO:0065009;regulation of a molecular function;0.000928078043756701!GO:0032508;DNA duplex unwinding;0.000942053855437224!GO:0032392;DNA geometric change;0.000942053855437224!GO:0031968;organelle outer membrane;0.000977365480778348!GO:0008250;oligosaccharyl transferase complex;0.0010409045888253!GO:0019867;outer membrane;0.00107339528897193!GO:0031970;organelle envelope lumen;0.00112531207622532!GO:0043492;ATPase activity, coupled to movement of substances;0.00113481637885384!GO:0031410;cytoplasmic vesicle;0.0011500308132451!GO:0006417;regulation of translation;0.00118116025484778!GO:0042802;identical protein binding;0.0012034675725618!GO:0043069;negative regulation of programmed cell death;0.00128930112066149!GO:0000096;sulfur amino acid metabolic process;0.00136182836843678!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00138320241879436!GO:0016481;negative regulation of transcription;0.00139596850480836!GO:0005769;early endosome;0.001409765057016!GO:0000082;G1/S transition of mitotic cell cycle;0.00147602047083223!GO:0005741;mitochondrial outer membrane;0.00150569607708071!GO:0005770;late endosome;0.00152675531980778!GO:0008047;enzyme activator activity;0.00157187478468659!GO:0005798;Golgi-associated vesicle;0.00157727542444653!GO:0009892;negative regulation of metabolic process;0.00160049352811924!GO:0043066;negative regulation of apoptosis;0.001604920038347!GO:0046474;glycerophospholipid biosynthetic process;0.00164022271674377!GO:0004003;ATP-dependent DNA helicase activity;0.00166707459753762!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00167823551546889!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00168764439359015!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00173899191090481!GO:0003711;transcription elongation regulator activity;0.00176366339987072!GO:0006284;base-excision repair;0.00177522562840884!GO:0046467;membrane lipid biosynthetic process;0.00182175323730119!GO:0000287;magnesium ion binding;0.00182385400510039!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.00182728152197909!GO:0048500;signal recognition particle;0.00187579107844802!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.00192996355483099!GO:0008312;7S RNA binding;0.00195604949404372!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00205711824029742!GO:0006338;chromatin remodeling;0.00218219500296835!GO:0006268;DNA unwinding during replication;0.00244462001013514!GO:0031072;heat shock protein binding;0.00252298444765237!GO:0032940;secretion by cell;0.00257003560842739!GO:0000922;spindle pole;0.00258554736056242!GO:0006916;anti-apoptosis;0.00262560708634581!GO:0004576;oligosaccharyl transferase activity;0.00262667524190703!GO:0032561;guanyl ribonucleotide binding;0.00262667524190703!GO:0019001;guanyl nucleotide binding;0.00262667524190703!GO:0018196;peptidyl-asparagine modification;0.00317994809591754!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00317994809591754!GO:0000178;exosome (RNase complex);0.00321112748666823!GO:0048471;perinuclear region of cytoplasm;0.00330173694046457!GO:0006650;glycerophospholipid metabolic process;0.00335539353105149!GO:0016126;sterol biosynthetic process;0.0034096322859452!GO:0005096;GTPase activator activity;0.0034096322859452!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0034322402037752!GO:0006270;DNA replication initiation;0.00348620239176349!GO:0043414;biopolymer methylation;0.00352461296926022!GO:0032259;methylation;0.00357098552863419!GO:0051539;4 iron, 4 sulfur cluster binding;0.0036751325228285!GO:0046489;phosphoinositide biosynthetic process;0.00385626720002138!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00387898071908847!GO:0000792;heterochromatin;0.00389127861039995!GO:0015036;disulfide oxidoreductase activity;0.00389127861039995!GO:0031326;regulation of cellular biosynthetic process;0.00389915229640087!GO:0035258;steroid hormone receptor binding;0.0039539484912159!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00397855605015605!GO:0045047;protein targeting to ER;0.00397855605015605!GO:0006144;purine base metabolic process;0.00403075758130166!GO:0005637;nuclear inner membrane;0.00406566913316484!GO:0007050;cell cycle arrest;0.00408793657563599!GO:0008408;3'-5' exonuclease activity;0.00412480148751068!GO:0005048;signal sequence binding;0.0041606785450398!GO:0006519;amino acid and derivative metabolic process;0.00416970477564567!GO:0016272;prefoldin complex;0.00426562784140523!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00443741892097229!GO:0033116;ER-Golgi intermediate compartment membrane;0.00446317785835691!GO:0032984;macromolecular complex disassembly;0.00453608230595742!GO:0030384;phosphoinositide metabolic process;0.00463626933252933!GO:0009124;nucleoside monophosphate biosynthetic process;0.00495770359012596!GO:0009123;nucleoside monophosphate metabolic process;0.00495770359012596!GO:0044431;Golgi apparatus part;0.00500996661556577!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.00502199488089156!GO:0030176;integral to endoplasmic reticulum membrane;0.00502651474444407!GO:0008287;protein serine/threonine phosphatase complex;0.00503016612673788!GO:0006289;nucleotide-excision repair;0.00520231427711415!GO:0031124;mRNA 3'-end processing;0.00523488600377068!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00543753744004479!GO:0043241;protein complex disassembly;0.00575211241865678!GO:0008632;apoptotic program;0.00585856449812606!GO:0016251;general RNA polymerase II transcription factor activity;0.00589207602573977!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.00590730755675494!GO:0045039;protein import into mitochondrial inner membrane;0.00590730755675494!GO:0031252;leading edge;0.00590730755675494!GO:0000228;nuclear chromosome;0.00592276815808099!GO:0005791;rough endoplasmic reticulum;0.00603992902317215!GO:0006730;one-carbon compound metabolic process;0.00605372550269697!GO:0015631;tubulin binding;0.0063347046815866!GO:0050790;regulation of catalytic activity;0.00636326226145801!GO:0009303;rRNA transcription;0.00636466034437202!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00658438014691648!GO:0030118;clathrin coat;0.00658620824485934!GO:0043284;biopolymer biosynthetic process;0.00686408617422192!GO:0006611;protein export from nucleus;0.00697032135022313!GO:0043624;cellular protein complex disassembly;0.00702384644539723!GO:0043596;nuclear replication fork;0.00707790028741625!GO:0006779;porphyrin biosynthetic process;0.00707790028741625!GO:0033014;tetrapyrrole biosynthetic process;0.00707790028741625!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00745573165889663!GO:0046128;purine ribonucleoside metabolic process;0.00745573165889663!GO:0042278;purine nucleoside metabolic process;0.00745573165889663!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00748440642579548!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00755161704959849!GO:0051252;regulation of RNA metabolic process;0.0077648283168664!GO:0006695;cholesterol biosynthetic process;0.0077648283168664!GO:0006118;electron transport;0.00780890167040104!GO:0000726;non-recombinational repair;0.00780890167040104!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.00807600779032247!GO:0009112;nucleobase metabolic process;0.00816063837815742!GO:0040029;regulation of gene expression, epigenetic;0.00818779099006173!GO:0006400;tRNA modification;0.00820839633496447!GO:0022411;cellular component disassembly;0.00833554453727651!GO:0016407;acetyltransferase activity;0.00851767194177497!GO:0005832;chaperonin-containing T-complex;0.00856759511805154!GO:0005669;transcription factor TFIID complex;0.00858587947866413!GO:0006778;porphyrin metabolic process;0.00880655941559772!GO:0033013;tetrapyrrole metabolic process;0.00880655941559772!GO:0006275;regulation of DNA replication;0.00892386633489987!GO:0006595;polyamine metabolic process;0.0093358738605932!GO:0000339;RNA cap binding;0.00952731712571077!GO:0003746;translation elongation factor activity;0.00960600345841209!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00971862214203878!GO:0007243;protein kinase cascade;0.00979558619530775!GO:0000725;recombinational repair;0.0100334047375095!GO:0000724;double-strand break repair via homologous recombination;0.0100334047375095!GO:0051789;response to protein stimulus;0.0100905168402564!GO:0006986;response to unfolded protein;0.0100905168402564!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0101257569470834!GO:0015002;heme-copper terminal oxidase activity;0.0101257569470834!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0101257569470834!GO:0004129;cytochrome-c oxidase activity;0.0101257569470834!GO:0003702;RNA polymerase II transcription factor activity;0.0103133394343963!GO:0006406;mRNA export from nucleus;0.0103772744096219!GO:0051287;NAD binding;0.0103828296597266!GO:0009066;aspartate family amino acid metabolic process;0.0104285155559706!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.010527472891855!GO:0009161;ribonucleoside monophosphate metabolic process;0.0107594949063442!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.0107594949063442!GO:0031570;DNA integrity checkpoint;0.0110931179826033!GO:0006220;pyrimidine nucleotide metabolic process;0.0112512670150936!GO:0004674;protein serine/threonine kinase activity;0.0112741869020822!GO:0030663;COPI coated vesicle membrane;0.0113196860592677!GO:0030126;COPI vesicle coat;0.0113196860592677!GO:0004532;exoribonuclease activity;0.0115160856925432!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0115160856925432!GO:0006007;glucose catabolic process;0.0115790537375576!GO:0031123;RNA 3'-end processing;0.0117136631994544!GO:0030041;actin filament polymerization;0.0119867026773791!GO:0016790;thiolester hydrolase activity;0.0120229127062508!GO:0006643;membrane lipid metabolic process;0.0120667135350579!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0123676265339938!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0124140926340651!GO:0000819;sister chromatid segregation;0.0124263492044482!GO:0048487;beta-tubulin binding;0.0124311942400787!GO:0009067;aspartate family amino acid biosynthetic process;0.0126787682410833!GO:0006378;mRNA polyadenylation;0.0126787682410833!GO:0008652;amino acid biosynthetic process;0.0127248691386657!GO:0043022;ribosome binding;0.0132131769591058!GO:0030218;erythrocyte differentiation;0.0135678394444973!GO:0008637;apoptotic mitochondrial changes;0.0137805142060332!GO:0000097;sulfur amino acid biosynthetic process;0.0141806868481408!GO:0050662;coenzyme binding;0.0142652015626205!GO:0008180;signalosome;0.0143209091788035!GO:0016584;nucleosome positioning;0.0143499112550654!GO:0000070;mitotic sister chromatid segregation;0.0143951049876048!GO:0007021;tubulin folding;0.0145297128427543!GO:0006783;heme biosynthetic process;0.0148764780351096!GO:0016044;membrane organization and biogenesis;0.0151497789335201!GO:0003725;double-stranded RNA binding;0.0160799587099438!GO:0007017;microtubule-based process;0.0160950906398579!GO:0043488;regulation of mRNA stability;0.0162130440299495!GO:0043487;regulation of RNA stability;0.0162130440299495!GO:0006376;mRNA splice site selection;0.0163538261140055!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0163538261140055!GO:0042393;histone binding;0.0167541006255066!GO:0000118;histone deacetylase complex;0.0172663058707851!GO:0032200;telomere organization and biogenesis;0.0179160149703221!GO:0000723;telomere maintenance;0.0179160149703221!GO:0051656;establishment of organelle localization;0.0180099378444832!GO:0009889;regulation of biosynthetic process;0.0183262405818479!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0184244161750007!GO:0043601;nuclear replisome;0.0187889377453487!GO:0030894;replisome;0.0187889377453487!GO:0016585;chromatin remodeling complex;0.0189893726003584!GO:0042168;heme metabolic process;0.0189893726003584!GO:0004177;aminopeptidase activity;0.0191266276712163!GO:0018193;peptidyl-amino acid modification;0.0193991105438879!GO:0022884;macromolecule transmembrane transporter activity;0.019495424704441!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.019495424704441!GO:0008139;nuclear localization sequence binding;0.0199502611058311!GO:0044438;microbody part;0.0199728499113819!GO:0044439;peroxisomal part;0.0199728499113819!GO:0019783;small conjugating protein-specific protease activity;0.0203936882129851!GO:0006607;NLS-bearing substrate import into nucleus;0.0204137634201571!GO:0006644;phospholipid metabolic process;0.020532380286028!GO:0007264;small GTPase mediated signal transduction;0.0217551837973173!GO:0008320;protein transmembrane transporter activity;0.0217851139965525!GO:0030119;AP-type membrane coat adaptor complex;0.0219321204254217!GO:0042770;DNA damage response, signal transduction;0.0220655939046395!GO:0004843;ubiquitin-specific protease activity;0.0220655939046395!GO:0006891;intra-Golgi vesicle-mediated transport;0.022429401220984!GO:0030521;androgen receptor signaling pathway;0.0229849932598946!GO:0005876;spindle microtubule;0.0236122309364991!GO:0031577;spindle checkpoint;0.0236276180590168!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0239135102365761!GO:0030508;thiol-disulfide exchange intermediate activity;0.0241961514195173!GO:0006506;GPI anchor biosynthetic process;0.0247265358438713!GO:0000139;Golgi membrane;0.0247750519076093!GO:0042158;lipoprotein biosynthetic process;0.0247807801821197!GO:0009396;folic acid and derivative biosynthetic process;0.0254140017433606!GO:0030131;clathrin adaptor complex;0.0254918912597892!GO:0031903;microbody membrane;0.0256404834759866!GO:0005778;peroxisomal membrane;0.0256404834759866!GO:0001726;ruffle;0.0264893385795388!GO:0008538;proteasome activator activity;0.0266147299360806!GO:0009116;nucleoside metabolic process;0.026766845549105!GO:0016197;endosome transport;0.0270170205721457!GO:0009119;ribonucleoside metabolic process;0.0271394165057196!GO:0048146;positive regulation of fibroblast proliferation;0.0272171702422217!GO:0004448;isocitrate dehydrogenase activity;0.0274035836210966!GO:0042026;protein refolding;0.0274646117634572!GO:0030137;COPI-coated vesicle;0.0274687503043308!GO:0030658;transport vesicle membrane;0.0274687503043308!GO:0000077;DNA damage checkpoint;0.0280277802378274!GO:0005744;mitochondrial inner membrane presequence translocase complex;0.028201089068118!GO:0051053;negative regulation of DNA metabolic process;0.0290273346485839!GO:0004523;ribonuclease H activity;0.0292161910364296!GO:0008234;cysteine-type peptidase activity;0.0292537214320902!GO:0030695;GTPase regulator activity;0.0295416111073935!GO:0048144;fibroblast proliferation;0.0295673672902118!GO:0048145;regulation of fibroblast proliferation;0.0295673672902118!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0295906312283238!GO:0005732;small nucleolar ribonucleoprotein complex;0.0300071732941775!GO:0005874;microtubule;0.0302145723716216!GO:0000152;nuclear ubiquitin ligase complex;0.0303834573011681!GO:0030518;steroid hormone receptor signaling pathway;0.0312721530249274!GO:0008017;microtubule binding;0.0315861234083781!GO:0008601;protein phosphatase type 2A regulator activity;0.0316657347431054!GO:0007010;cytoskeleton organization and biogenesis;0.0317375822334654!GO:0000793;condensed chromosome;0.03220171480259!GO:0045892;negative regulation of transcription, DNA-dependent;0.0326520798865008!GO:0008276;protein methyltransferase activity;0.0326520798865008!GO:0046365;monosaccharide catabolic process;0.0328237333340745!GO:0031371;ubiquitin conjugating enzyme complex;0.0328592479556144!GO:0006979;response to oxidative stress;0.0330005775475581!GO:0008022;protein C-terminus binding;0.0330036318516619!GO:0008097;5S rRNA binding;0.0336459175182885!GO:0050681;androgen receptor binding;0.0336540108140504!GO:0006740;NADPH regeneration;0.0336840368495081!GO:0006098;pentose-phosphate shunt;0.0336840368495081!GO:0006497;protein amino acid lipidation;0.0336840368495081!GO:0048037;cofactor binding;0.0339715781840564!GO:0004221;ubiquitin thiolesterase activity;0.0346648043065004!GO:0001522;pseudouridine synthesis;0.034967557028678!GO:0006505;GPI anchor metabolic process;0.0350375890988482!GO:0043189;H4/H2A histone acetyltransferase complex;0.035103950940318!GO:0006555;methionine metabolic process;0.0355194518094072!GO:0005869;dynactin complex;0.0356904887957361!GO:0005851;eukaryotic translation initiation factor 2B complex;0.0368882851759912!GO:0030132;clathrin coat of coated pit;0.0368965421065653!GO:0022406;membrane docking;0.0370864131932141!GO:0048278;vesicle docking;0.0370864131932141!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0373351299733!GO:0006360;transcription from RNA polymerase I promoter;0.0374687382306083!GO:0032287;myelin maintenance in the peripheral nervous system;0.0386282356985123!GO:0032838;cell projection cytoplasm;0.0386282356985123!GO:0033081;regulation of T cell differentiation in the thymus;0.0386282356985123!GO:0043217;myelin maintenance;0.0386282356985123!GO:0060087;relaxation of vascular smooth muscle;0.0386282356985123!GO:0032839;dendrite cytoplasm;0.0386282356985123!GO:0009081;branched chain family amino acid metabolic process;0.0389201807939875!GO:0000175;3'-5'-exoribonuclease activity;0.0389201807939875!GO:0030036;actin cytoskeleton organization and biogenesis;0.0403598578138449!GO:0030320;cellular monovalent inorganic anion homeostasis;0.0403598578138449!GO:0055083;monovalent inorganic anion homeostasis;0.0403598578138449!GO:0055064;chloride ion homeostasis;0.0403598578138449!GO:0030644;cellular chloride ion homeostasis;0.0403598578138449!GO:0045576;mast cell activation;0.0403873772354122!GO:0003756;protein disulfide isomerase activity;0.0404513759937261!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0404513759937261!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0404513759937261!GO:0006733;oxidoreduction coenzyme metabolic process;0.0407155846916896!GO:0050178;phenylpyruvate tautomerase activity;0.0410644227887636!GO:0006672;ceramide metabolic process;0.0410944296323253!GO:0003887;DNA-directed DNA polymerase activity;0.0411072946266373!GO:0035267;NuA4 histone acetyltransferase complex;0.041319124032553!GO:0007265;Ras protein signal transduction;0.0413574444341168!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0413574444341168!GO:0042769;DNA damage response, detection of DNA damage;0.0413574444341168!GO:0000123;histone acetyltransferase complex;0.0414122710497154!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.0414122710497154!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.0414122710497154!GO:0009126;purine nucleoside monophosphate metabolic process;0.0414122710497154!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.0414122710497154!GO:0004300;enoyl-CoA hydratase activity;0.0415907256682787!GO:0016860;intramolecular oxidoreductase activity;0.042008276322431!GO:0005784;translocon complex;0.0423062686596314!GO:0030433;ER-associated protein catabolic process;0.0424622349639675!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0424622349639675!GO:0030134;ER to Golgi transport vesicle;0.0428402861618223!GO:0030522;intracellular receptor-mediated signaling pathway;0.0429269774279838!GO:0030660;Golgi-associated vesicle membrane;0.0432267460859737!GO:0006769;nicotinamide metabolic process;0.0437665104376453!GO:0005663;DNA replication factor C complex;0.0437665104376453!GO:0000303;response to superoxide;0.0438248971191832!GO:0032404;mismatch repair complex binding;0.0440474983596689!GO:0004659;prenyltransferase activity;0.0440474983596689!GO:0046519;sphingoid metabolic process;0.0452361530628104!GO:0030911;TPR domain binding;0.045482699064804!GO:0044454;nuclear chromosome part;0.045482699064804!GO:0022415;viral reproductive process;0.0455355836330792!GO:0046164;alcohol catabolic process;0.0457349356580327!GO:0004239;methionyl aminopeptidase activity;0.0460902771374489!GO:0046112;nucleobase biosynthetic process;0.0461042193247938!GO:0019206;nucleoside kinase activity;0.0470167592537345!GO:0031647;regulation of protein stability;0.0475206150189894!GO:0019320;hexose catabolic process;0.0476639159413721!GO:0005092;GDP-dissociation inhibitor activity;0.0484310173488132!GO:0001832;blastocyst growth;0.04847222211834!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.048628303739047!GO:0004748;ribonucleoside-diphosphate reductase activity;0.0487460960537172!GO:0016728;oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor;0.0487460960537172!GO:0031503;protein complex localization;0.0489901076061987!GO:0008144;drug binding;0.049082000066624!GO:0006904;vesicle docking during exocytosis;0.0495787595733144!GO:0044262;cellular carbohydrate metabolic process;0.0495980601600225!GO:0045090;retroviral genome replication;0.049878167298415!GO:0043631;RNA polyadenylation;0.049878167298415!GO:0005773;vacuole;0.049878167298415!GO:0003985;acetyl-CoA C-acetyltransferase activity;0.049878167298415 | |||
|sample_id=10837 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=GATA6:3.41116887503;ALX1:2.24219614767;MYB:1.51538073445;E2F1..5:1.26693290325;NFY{A,B,C}:1.2301010305;HOXA9_MEIS1:1.21238255465;ZNF143:1.19629519989;NR6A1:1.13884650161;PBX1:1.12348095401;PITX1..3:1.10576598723;PAX4:1.10395864647;STAT1,3:1.09849025438;HES1:1.06749643251;STAT5{A,B}:1.02485548172;POU1F1:1.01167225671;PPARG:1.00344039959;AIRE:1.00161776714;PAX8:0.965830298484;ELK1,4_GABP{A,B1}:0.955713721634;POU2F1..3:0.909808490731;HOX{A6,A7,B6,B7}:0.907277544746;NR5A1,2:0.869661870247;ELF1,2,4:0.80470354992;YY1:0.791612974957;FOXD3:0.755066335225;ZBTB16:0.733737586947;POU6F1:0.710998373731;bHLH_family:0.687054977455;SPIB:0.647328214291;CRX:0.623478310272;RBPJ:0.623070590583;FOX{I1,J2}:0.548891209264;IKZF2:0.54665203149;SOX{8,9,10}:0.533622143296;NRF1:0.472994215117;EN1,2:0.467689929698;LHX3,4:0.459236276701;AR:0.442749952401;SPI1:0.415095513202;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.401358774626;ZNF148:0.332975288289;HOX{A4,D4}:0.316569704038;CDX1,2,4:0.315626890807;OCT4_SOX2{dimer}:0.310215190949;BREu{core}:0.303985269424;RXR{A,B,G}:0.303874071122;ETS1,2:0.29150338242;RORA:0.287297167682;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.270597292557;PAX6:0.260128014702;NANOG:0.244571600127;ARID5B:0.202399052252;ONECUT1,2:0.198517546198;FOXP1:0.174585999338;ADNP_IRX_SIX_ZHX:0.172148699486;FOXP3:0.150667074329;NFE2L1:0.143962243538;NKX2-1,4:0.128046408505;NKX2-2,8:0.125715347686;RUNX1..3:0.100427557735;HNF4A_NR2F1,2:0.0865565007629;POU3F1..4:0.0501254727467;PRRX1,2:0.0466133709163;HOX{A5,B5}:0.0349958077156;MYBL2:0.024106044341;CUX2:0.0111296242352;SOX17:-0.0311753996708;REST:-0.0425492583324;FOXQ1:-0.0567925473994;TGIF1:-0.0708856527024;NFIX:-0.0917684382906;EVI1:-0.0977792399066;DMAP1_NCOR{1,2}_SMARC:-0.102823185021;SNAI1..3:-0.106931008561;VSX1,2:-0.11580876225;NKX3-2:-0.128021780499;TFAP4:-0.148378805433;FOXN1:-0.164879591143;TOPORS:-0.179215803201;NFE2:-0.198802893671;HAND1,2:-0.221842217083;KLF4:-0.237058683234;TFDP1:-0.237219630111;ATF5_CREB3:-0.238836239092;GCM1,2:-0.252846733585;POU5F1:-0.277941560282;SMAD1..7,9:-0.280123424688;RFX2..5_RFXANK_RFXAP:-0.286015575284;NKX3-1:-0.288884933468;FOXA2:-0.304760037846;HNF1A:-0.316010217169;IRF7:-0.323109704875;HSF1,2:-0.32586766368;NANOG{mouse}:-0.333309542582;ZNF238:-0.335744658213;TLX2:-0.33854432903;UFEwm:-0.360211729533;GFI1:-0.364075284719;LEF1_TCF7_TCF7L1,2:-0.379140365695;NFKB1_REL_RELA:-0.383430782754;T:-0.387683761594;ZFP161:-0.394831779334;SOX5:-0.396205189345;PAX1,9:-0.399772203804;PAX5:-0.424916890839;ZNF423:-0.426297753786;NHLH1,2:-0.46150508786;AHR_ARNT_ARNT2:-0.463980084778;MEF2{A,B,C,D}:-0.464675390212;NFIL3:-0.465414483465;XBP1:-0.483224398666;ZNF384:-0.49484235839;ESRRA:-0.502450200427;TEF:-0.507195234103;GATA4:-0.508873434079;ZEB1:-0.529627949908;MZF1:-0.559355655561;MYOD1:-0.559644492378;PAX2:-0.567211220259;ZBTB6:-0.568012671624;IRF1,2:-0.574602925589;RREB1:-0.608400537266;RXRA_VDR{dimer}:-0.626116606318;NKX2-3_NKX2-5:-0.628146367669;HIF1A:-0.630099066779;GTF2I:-0.632470535707;HMGA1,2:-0.633951635359;FOSL2:-0.638035988083;NFE2L2:-0.652176986912;BACH2:-0.660258490506;FOS_FOS{B,L1}_JUN{B,D}:-0.670666580378;FOXM1:-0.67923015191;ZIC1..3:-0.711900348126;DBP:-0.720528153714;GTF2A1,2:-0.72307104315;CEBPA,B_DDIT3:-0.726919744858;HLF:-0.740762934747;NKX6-1,2:-0.753781797922;SRF:-0.764433165776;TLX1..3_NFIC{dimer}:-0.790794690485;NFATC1..3:-0.79590433227;MYFfamily:-0.803166999845;IKZF1:-0.810230174623;PAX3,7:-0.812877805555;MAFB:-0.821900657599;RFX1:-0.823543444321;FOX{F1,F2,J1}:-0.826217249086;HBP1_HMGB_SSRP1_UBTF:-0.84472383105;ATF4:-0.851131804337;SOX2:-0.864139012652;SREBF1,2:-0.873298890853;TFAP2{A,C}:-0.878089783391;TEAD1:-0.883069829849;EBF1:-0.914103478832;CREB1:-0.916065395441;XCPE1{core}:-0.919144269566;GZF1:-0.951875184224;PRDM1:-0.953216865181;BPTF:-0.955525847636;HMX1:-0.990261742982;EP300:-0.996399947723;EGR1..3:-1.00850507953;NR1H4:-1.02900595616;STAT2,4,6:-1.04036089629;MAZ:-1.05679004205;HIC1:-1.07467898941;ATF6:-1.11136291329;PATZ1:-1.12729798577;TAL1_TCF{3,4,12}:-1.1444354146;ATF2:-1.21832685421;FOXO1,3,4:-1.23343102156;SP1:-1.25255145939;GLI1..3:-1.25866011827;JUN:-1.26373831575;FOXL1:-1.28333622949;TP53:-1.2920354539;MTF1:-1.30697054642;SPZ1:-1.36866370261;TBP:-1.37605583132;MTE{core}:-1.38246148588;CDC5L:-1.3936227006;MED-1{core}:-1.39478266226;GFI1B:-1.43466443389;FOX{D1,D2}:-1.44215619461;TFAP2B:-1.47231785815;PDX1:-1.50645517464;NR3C1:-1.52841585872;LMO2:-1.65513331396;TBX4,5:-1.71323403554;ALX4:-1.78891411277;ESR1:-1.79170649973;TFCP2:-2.49784825387 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10837-111D9;search_select_hide=table117:FF:10837-111D9 | |||
}} | }} |
Latest revision as of 15:08, 3 June 2020
Name: | acute myeloid leukemia (FAB M6) cell line:F-36P |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13505 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13505
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13505
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0192 |
10 | 10 | 0.022 |
100 | 100 | 0.476 |
101 | 101 | 0.235 |
102 | 102 | 0.464 |
103 | 103 | 0.138 |
104 | 104 | 0.771 |
105 | 105 | 0.727 |
106 | 106 | 0.453 |
107 | 107 | 0.397 |
108 | 108 | 0.368 |
109 | 109 | 0.0217 |
11 | 11 | 0.0555 |
110 | 110 | 0.411 |
111 | 111 | 0.0204 |
112 | 112 | 0.401 |
113 | 113 | 0.465 |
114 | 114 | 0.0156 |
115 | 115 | 0.225 |
116 | 116 | 0.168 |
117 | 117 | 0.0392 |
118 | 118 | 0.185 |
119 | 119 | 0.385 |
12 | 12 | 0.603 |
120 | 120 | 0.911 |
121 | 121 | 0.734 |
122 | 122 | 0.71 |
123 | 123 | 0.28 |
124 | 124 | 0.0356 |
125 | 125 | 0.259 |
126 | 126 | 0.33 |
127 | 127 | 0.136 |
128 | 128 | 0.319 |
129 | 129 | 0.613 |
13 | 13 | 0.0067 |
130 | 130 | 0.542 |
131 | 131 | 0.539 |
132 | 132 | 0.367 |
133 | 133 | 0.884 |
134 | 134 | 0.314 |
135 | 135 | 0.681 |
136 | 136 | 0.377 |
137 | 137 | 0.752 |
138 | 138 | 0.721 |
139 | 139 | 0.283 |
14 | 14 | 0.323 |
140 | 140 | 0.792 |
141 | 141 | 0.515 |
142 | 142 | 0.664 |
143 | 143 | 0.801 |
144 | 144 | 0.335 |
145 | 145 | 0.21 |
146 | 146 | 0.986 |
147 | 147 | 0.0699 |
148 | 148 | 0.435 |
149 | 149 | 0.2 |
15 | 15 | 0.228 |
150 | 150 | 0.66 |
151 | 151 | 0.818 |
152 | 152 | 0.239 |
153 | 153 | 0.184 |
154 | 154 | 0.899 |
155 | 155 | 0.221 |
156 | 156 | 0.25 |
157 | 157 | 0.441 |
158 | 158 | 0.954 |
159 | 159 | 0.37 |
16 | 16 | 0.946 |
160 | 160 | 0.0702 |
161 | 161 | 0.0141 |
162 | 162 | 0.815 |
163 | 163 | 0.109 |
164 | 164 | 0.78 |
165 | 165 | 0.8 |
166 | 166 | 0.275 |
167 | 167 | 0.158 |
168 | 168 | 0.719 |
169 | 169 | 0.435 |
17 | 17 | 0.641 |
18 | 18 | 0.839 |
19 | 19 | 0.778 |
2 | 2 | 0.439 |
20 | 20 | 0.716 |
21 | 21 | 0.105 |
22 | 22 | 0.736 |
23 | 23 | 0.0256 |
24 | 24 | 0.0678 |
25 | 25 | 0.289 |
26 | 26 | 0.0164 |
27 | 27 | 0.856 |
28 | 28 | 0.813 |
29 | 29 | 0.0311 |
3 | 3 | 0.147 |
30 | 30 | 0.106 |
31 | 31 | 0.658 |
32 | 32 | 0.0602 |
33 | 33 | 0.255 |
34 | 34 | 0.773 |
35 | 35 | 0.19 |
36 | 36 | 0.0557 |
37 | 37 | 0.291 |
38 | 38 | 0.353 |
39 | 39 | 0.219 |
4 | 4 | 0.152 |
40 | 40 | 0.279 |
41 | 41 | 0.858 |
42 | 42 | 0.184 |
43 | 43 | 0.533 |
44 | 44 | 0.937 |
45 | 45 | 0.918 |
46 | 46 | 0.19 |
47 | 47 | 0.0424 |
48 | 48 | 0.074 |
49 | 49 | 0.173 |
5 | 5 | 0.561 |
50 | 50 | 0.669 |
51 | 51 | 0.533 |
52 | 52 | 0.264 |
53 | 53 | 0.381 |
54 | 54 | 0.414 |
55 | 55 | 0.224 |
56 | 56 | 0.898 |
57 | 57 | 0.0895 |
58 | 58 | 0.315 |
59 | 59 | 0.691 |
6 | 6 | 0.395 |
60 | 60 | 0.957 |
61 | 61 | 0.472 |
62 | 62 | 0.213 |
63 | 63 | 0.82 |
64 | 64 | 0.231 |
65 | 65 | 0.994 |
66 | 66 | 0.0015 |
67 | 67 | 0.471 |
68 | 68 | 0.504 |
69 | 69 | 0.869 |
7 | 7 | 0.0578 |
70 | 70 | 0.92 |
71 | 71 | 0.0157 |
72 | 72 | 0.962 |
73 | 73 | 0.985 |
74 | 74 | 0.99 |
75 | 75 | 0.0198 |
76 | 76 | 0.221 |
77 | 77 | 0.47 |
78 | 78 | 0.0068 |
79 | 79 | 0.121 |
8 | 8 | 0.0571 |
80 | 80 | 0.0686 |
81 | 81 | 0.427 |
82 | 82 | 0.792 |
83 | 83 | 0.0346 |
84 | 84 | 0.886 |
85 | 85 | 0.837 |
86 | 86 | 0.969 |
87 | 87 | 0.192 |
88 | 88 | 0.185 |
89 | 89 | 0.725 |
9 | 9 | 0.999 |
90 | 90 | 0.0185 |
91 | 91 | 0.642 |
92 | 92 | 0.352 |
93 | 93 | 0.575 |
94 | 94 | 0.556 |
95 | 95 | 0.0179 |
96 | 96 | 0.996 |
97 | 97 | 0.38 |
98 | 98 | 0.228 |
99 | 99 | 0.825 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13505
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0101883 acute myeloid leukemia cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
1240 (leukemia)
8692 (myeloid leukemia)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100737 (leukemia cell line sample)
0101035 (hematopoietic cell line sample)
0101883 (acute myeloid leukemia cell line sample)
0100740 (myeloid leukemia cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)