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{{f5samples
{{f5samples
|DRA_sample_Accession=CAGE@SAMD00004687
|DRA_sample_Accession=CAGE@SAMD00004687
|accession_numbers=CAGE;DRX008321;DRR009193;DRZ000618;DRZ002003
|accession_numbers=CAGE;DRX008321;DRR009193;DRZ000618;DRZ002003;DRZ011968;DRZ013353
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|ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0000970,UBERON:0000019,UBERON:0000483,UBERON:0000033,UBERON:0000479,UBERON:0004121,UBERON:0000064,UBERON:0010314,UBERON:0000047,UBERON:0000062,UBERON:0000475,UBERON:0000061,UBERON:0000465,UBERON:0000063,UBERON:0001444,UBERON:0000477,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0000119,UBERON:0000490,UBERON:0010077,UBERON:0005389,UBERON:0000020,UBERON:0010371,UBERON:0007625,UBERON:0000484,UBERON:0001032,UBERON:0010317,UBERON:0000965,UBERON:0001803,UBERON:0004088,UBERON:0000153,UBERON:0007811,UBERON:0002104,UBERON:0001801,UBERON:0004456,UBERON:0001456,UBERON:0010230
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0000075,CL:0000066,CL:0002371,CL:0000325,CL:0000255,CL:0000306,CL:0002222,CL:0002224
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0000075,CL:0000066,CL:0002371,CL:0000325,CL:0000255,CL:0000306,CL:0002222,CL:0002224
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|microRNAs=
|microRNAs=
|microRNAs_nn=
|microRNAs_nn=
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer/#/human#cage;sample;11690
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11690
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer_novel/#/human#cage;sample;11690
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11690
|name=Lens Epithelial Cells, donor3
|name=Lens Epithelial Cells, donor3
|namespace=FANTOM5
|namespace=FANTOM5
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|profile_rnaseq=
|profile_rnaseq=
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|profile_srnaseq=,,,
|refex=http://refex.dbcls.jp/genelist.php?lang=en&db=human&roku_valid=1&rk[]=&order_key=score
|refex=http://refex.dbcls.jp/genelist.php?lang
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Line 100: Line 100:
|top_motifs=NKX3-1:1.67458090786;PAX1,9:1.43948876933;NKX2-1,4:1.39311545787;SOX17:1.34922324561;TAL1_TCF{3,4,12}:1.26360954985;NFATC1..3:1.23781901264;HSF1,2:1.20486422597;SRF:1.20156797369;MAZ:1.19669779524;TEAD1:1.18602556062;NR3C1:1.14600659144;HIF1A:1.1082525395;EN1,2:1.10810519432;MZF1:1.08030255374;HOX{A5,B5}:1.03222867532;SOX2:0.985583607861;TFAP4:0.972544973297;ZNF384:0.95592569357;T:0.930615005345;IKZF1:0.913015505665;GTF2A1,2:0.902052300206;MTE{core}:0.890286127921;POU3F1..4:0.882811056484;ATF6:0.862442156426;TBX4,5:0.850887673411;NANOG{mouse}:0.839996168007;SMAD1..7,9:0.832268455679;MYBL2:0.826551290137;GLI1..3:0.819945114044;PATZ1:0.818357976883;NHLH1,2:0.784699212228;TFAP2{A,C}:0.773109598019;TP53:0.769993216088;GTF2I:0.754009469398;TFCP2:0.724785109751;TLX1..3_NFIC{dimer}:0.706795583492;FOXA2:0.694169239519;LHX3,4:0.669436771304;NANOG:0.658423414898;GFI1B:0.655309768394;POU5F1:0.61474953148;ZFP161:0.608167897766;ZNF148:0.60581283662;EGR1..3:0.596703741776;NKX2-3_NKX2-5:0.587812843673;DBP:0.581126999405;CDC5L:0.553082161845;PAX5:0.536288095205;EBF1:0.526109324033;KLF4:0.514478462286;PRDM1:0.498185934662;MYFfamily:0.479876273046;MAFB:0.47853596945;TBP:0.468760747721;CRX:0.45980369185;ADNP_IRX_SIX_ZHX:0.458584868453;SP1:0.455328727188;ONECUT1,2:0.443751842858;LEF1_TCF7_TCF7L1,2:0.438116609269;AHR_ARNT_ARNT2:0.412194525861;ALX1:0.410811395206;NR6A1:0.389954898913;PAX4:0.371970830638;FOXN1:0.351773609111;HIC1:0.351198949858;PDX1:0.346814457573;GFI1:0.341707761391;ZNF423:0.339746424514;GATA4:0.336169337536;NFE2L2:0.316447550594;PAX8:0.315174128704;PRRX1,2:0.307559452183;ZIC1..3:0.305523415376;HOX{A4,D4}:0.301903632677;XCPE1{core}:0.301264701944;FOSL2:0.295775808938;TFAP2B:0.286858289188;NKX3-2:0.281702656678;RXR{A,B,G}:0.274407763198;VSX1,2:0.261164804933;NRF1:0.223182694904;ALX4:0.217496264713;EVI1:0.213501677471;TLX2:0.205982229324;HMGA1,2:0.200646831276;XBP1:0.198554114306;ZBTB6:0.190170841652;TFDP1:0.170107182689;STAT5{A,B}:0.160391202865;NFE2L1:0.15612242294;HOXA9_MEIS1:0.152984500573;NFIX:0.138738316922;MED-1{core}:0.138586080087;FOXM1:0.136864155107;JUN:0.132768332948;STAT1,3:0.12224464556;ELK1,4_GABP{A,B1}:0.1143591815;NFY{A,B,C}:0.0917675012653;RORA:0.0839246809576;ZNF143:0.0836742688914;TEF:0.0834139449426;REST:0.0516880823287;HNF1A:0.0478759129894;AR:0.0351637172283;BACH2:0.0348697300141;AIRE:0.0325187186054;FOXP3:0.0282892224121;HLF:0.022446491684;UFEwm:0.0163746298552;RFX1:0.0155969145082;ELF1,2,4:0.0114171446822;HNF4A_NR2F1,2:0.0087330075171;SPZ1:-0.00355215340229;HOX{A6,A7,B6,B7}:-0.00649853712399;bHLH_family:-0.0101732179176;NFE2:-0.0237164732144;NR1H4:-0.0355901344537;GZF1:-0.0359008252364;CUX2:-0.0449482967533;RBPJ:-0.047398418698;FOXQ1:-0.0652994981583;NFIL3:-0.0711118850371;MEF2{A,B,C,D}:-0.0784443691061;GATA6:-0.0821938502787;POU6F1:-0.0825568209298;PAX6:-0.0964393956702;MYOD1:-0.102091955371;FOX{D1,D2}:-0.107310536345;RREB1:-0.110916122746;MTF1:-0.114777491656;PAX2:-0.11590239335;IRF7:-0.12476763092;FOS_FOS{B,L1}_JUN{B,D}:-0.132322190524;OCT4_SOX2{dimer}:-0.136370413265;HMX1:-0.136948221071;HAND1,2:-0.13757893622;ATF2:-0.138914546963;CDX1,2,4:-0.140819645839;TGIF1:-0.149885906859;ZNF238:-0.160305452065;PPARG:-0.164789116545;SOX5:-0.184558695975;PBX1:-0.185997436751;CEBPA,B_DDIT3:-0.195885604859;IRF1,2:-0.196148279387;SREBF1,2:-0.206890028898;RUNX1..3:-0.225016570061;SOX{8,9,10}:-0.253273102409;ATF4:-0.274335692534;FOX{I1,J2}:-0.276497232213;NFKB1_REL_RELA:-0.280782494275;HBP1_HMGB_SSRP1_UBTF:-0.29598086777;BREu{core}:-0.316259834833;ZEB1:-0.322596697214;FOX{F1,F2,J1}:-0.322838282573;SNAI1..3:-0.325800186995;LMO2:-0.331817123215;EP300:-0.349750368321;ETS1,2:-0.351187139085;MYB:-0.377507594249;TOPORS:-0.379376853544;NR5A1,2:-0.379953936866;ATF5_CREB3:-0.3829318602;SPI1:-0.385737782584;STAT2,4,6:-0.392629418042;GCM1,2:-0.423419922596;E2F1..5:-0.479510880058;ESRRA:-0.5031493446;YY1:-0.516139765613;SPIB:-0.526116057979;NKX2-2,8:-0.530262343473;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.530728263858;BPTF:-0.535896672523;ARID5B:-0.540648524139;DMAP1_NCOR{1,2}_SMARC:-0.54463842395;RFX2..5_RFXANK_RFXAP:-0.567803995577;POU2F1..3:-0.56783071965;FOXL1:-0.620979006965;RXRA_VDR{dimer}:-0.647022361766;POU1F1:-0.65316290194;ESR1:-0.688416561939;FOXO1,3,4:-0.730227491875;PAX3,7:-0.822284658351;NKX6-1,2:-0.891287515332;ZBTB16:-0.920160397998;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.950518278456;CREB1:-0.954637039973;IKZF2:-1.01000316417;HES1:-1.09708170538;PITX1..3:-1.09719954736;FOXP1:-1.18917940598;FOXD3:-1.26546068335
|top_motifs=NKX3-1:1.67458090786;PAX1,9:1.43948876933;NKX2-1,4:1.39311545787;SOX17:1.34922324561;TAL1_TCF{3,4,12}:1.26360954985;NFATC1..3:1.23781901264;HSF1,2:1.20486422597;SRF:1.20156797369;MAZ:1.19669779524;TEAD1:1.18602556062;NR3C1:1.14600659144;HIF1A:1.1082525395;EN1,2:1.10810519432;MZF1:1.08030255374;HOX{A5,B5}:1.03222867532;SOX2:0.985583607861;TFAP4:0.972544973297;ZNF384:0.95592569357;T:0.930615005345;IKZF1:0.913015505665;GTF2A1,2:0.902052300206;MTE{core}:0.890286127921;POU3F1..4:0.882811056484;ATF6:0.862442156426;TBX4,5:0.850887673411;NANOG{mouse}:0.839996168007;SMAD1..7,9:0.832268455679;MYBL2:0.826551290137;GLI1..3:0.819945114044;PATZ1:0.818357976883;NHLH1,2:0.784699212228;TFAP2{A,C}:0.773109598019;TP53:0.769993216088;GTF2I:0.754009469398;TFCP2:0.724785109751;TLX1..3_NFIC{dimer}:0.706795583492;FOXA2:0.694169239519;LHX3,4:0.669436771304;NANOG:0.658423414898;GFI1B:0.655309768394;POU5F1:0.61474953148;ZFP161:0.608167897766;ZNF148:0.60581283662;EGR1..3:0.596703741776;NKX2-3_NKX2-5:0.587812843673;DBP:0.581126999405;CDC5L:0.553082161845;PAX5:0.536288095205;EBF1:0.526109324033;KLF4:0.514478462286;PRDM1:0.498185934662;MYFfamily:0.479876273046;MAFB:0.47853596945;TBP:0.468760747721;CRX:0.45980369185;ADNP_IRX_SIX_ZHX:0.458584868453;SP1:0.455328727188;ONECUT1,2:0.443751842858;LEF1_TCF7_TCF7L1,2:0.438116609269;AHR_ARNT_ARNT2:0.412194525861;ALX1:0.410811395206;NR6A1:0.389954898913;PAX4:0.371970830638;FOXN1:0.351773609111;HIC1:0.351198949858;PDX1:0.346814457573;GFI1:0.341707761391;ZNF423:0.339746424514;GATA4:0.336169337536;NFE2L2:0.316447550594;PAX8:0.315174128704;PRRX1,2:0.307559452183;ZIC1..3:0.305523415376;HOX{A4,D4}:0.301903632677;XCPE1{core}:0.301264701944;FOSL2:0.295775808938;TFAP2B:0.286858289188;NKX3-2:0.281702656678;RXR{A,B,G}:0.274407763198;VSX1,2:0.261164804933;NRF1:0.223182694904;ALX4:0.217496264713;EVI1:0.213501677471;TLX2:0.205982229324;HMGA1,2:0.200646831276;XBP1:0.198554114306;ZBTB6:0.190170841652;TFDP1:0.170107182689;STAT5{A,B}:0.160391202865;NFE2L1:0.15612242294;HOXA9_MEIS1:0.152984500573;NFIX:0.138738316922;MED-1{core}:0.138586080087;FOXM1:0.136864155107;JUN:0.132768332948;STAT1,3:0.12224464556;ELK1,4_GABP{A,B1}:0.1143591815;NFY{A,B,C}:0.0917675012653;RORA:0.0839246809576;ZNF143:0.0836742688914;TEF:0.0834139449426;REST:0.0516880823287;HNF1A:0.0478759129894;AR:0.0351637172283;BACH2:0.0348697300141;AIRE:0.0325187186054;FOXP3:0.0282892224121;HLF:0.022446491684;UFEwm:0.0163746298552;RFX1:0.0155969145082;ELF1,2,4:0.0114171446822;HNF4A_NR2F1,2:0.0087330075171;SPZ1:-0.00355215340229;HOX{A6,A7,B6,B7}:-0.00649853712399;bHLH_family:-0.0101732179176;NFE2:-0.0237164732144;NR1H4:-0.0355901344537;GZF1:-0.0359008252364;CUX2:-0.0449482967533;RBPJ:-0.047398418698;FOXQ1:-0.0652994981583;NFIL3:-0.0711118850371;MEF2{A,B,C,D}:-0.0784443691061;GATA6:-0.0821938502787;POU6F1:-0.0825568209298;PAX6:-0.0964393956702;MYOD1:-0.102091955371;FOX{D1,D2}:-0.107310536345;RREB1:-0.110916122746;MTF1:-0.114777491656;PAX2:-0.11590239335;IRF7:-0.12476763092;FOS_FOS{B,L1}_JUN{B,D}:-0.132322190524;OCT4_SOX2{dimer}:-0.136370413265;HMX1:-0.136948221071;HAND1,2:-0.13757893622;ATF2:-0.138914546963;CDX1,2,4:-0.140819645839;TGIF1:-0.149885906859;ZNF238:-0.160305452065;PPARG:-0.164789116545;SOX5:-0.184558695975;PBX1:-0.185997436751;CEBPA,B_DDIT3:-0.195885604859;IRF1,2:-0.196148279387;SREBF1,2:-0.206890028898;RUNX1..3:-0.225016570061;SOX{8,9,10}:-0.253273102409;ATF4:-0.274335692534;FOX{I1,J2}:-0.276497232213;NFKB1_REL_RELA:-0.280782494275;HBP1_HMGB_SSRP1_UBTF:-0.29598086777;BREu{core}:-0.316259834833;ZEB1:-0.322596697214;FOX{F1,F2,J1}:-0.322838282573;SNAI1..3:-0.325800186995;LMO2:-0.331817123215;EP300:-0.349750368321;ETS1,2:-0.351187139085;MYB:-0.377507594249;TOPORS:-0.379376853544;NR5A1,2:-0.379953936866;ATF5_CREB3:-0.3829318602;SPI1:-0.385737782584;STAT2,4,6:-0.392629418042;GCM1,2:-0.423419922596;E2F1..5:-0.479510880058;ESRRA:-0.5031493446;YY1:-0.516139765613;SPIB:-0.526116057979;NKX2-2,8:-0.530262343473;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.530728263858;BPTF:-0.535896672523;ARID5B:-0.540648524139;DMAP1_NCOR{1,2}_SMARC:-0.54463842395;RFX2..5_RFXANK_RFXAP:-0.567803995577;POU2F1..3:-0.56783071965;FOXL1:-0.620979006965;RXRA_VDR{dimer}:-0.647022361766;POU1F1:-0.65316290194;ESR1:-0.688416561939;FOXO1,3,4:-0.730227491875;PAX3,7:-0.822284658351;NKX6-1,2:-0.891287515332;ZBTB16:-0.920160397998;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.950518278456;CREB1:-0.954637039973;IKZF2:-1.01000316417;HES1:-1.09708170538;PITX1..3:-1.09719954736;FOXP1:-1.18917940598;FOXD3:-1.26546068335
|xref=
|xref=
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11690-122I7;search_select_hide=table117:FF:11690-122I7
}}
}}

Latest revision as of 18:15, 4 June 2020

Name:Lens Epithelial Cells, donor3
Species:Human (Homo sapiens)
Library ID:CNhs12572
Sample type:primary cells
Genomic View: UCSC
RefEX:Specific genes
FANTOM CAT:1, 2, 3, 4, 5
CAGEd-oPOSSUM:link
ZENBU report :link
Additional information
Sample information
strainNA
tissueeye
dev stageNA
sexNA
ageNA
cell typelens epithelial cell
cell lineNA
companySciencell/3H
collaborationFANTOM5 OSC CORE (contact: Al Forrest)
External link for information[{{{sample_info_link}}} {{{sample_info_link}}}]
RNA information
lot number6756
catalog numberSC6555
sample typetotal RNA
extraction protocol (Details)OP-RNA-extraction-totalRNA-TRIzol-ethanol-v1.0

CAGE Accession numbers
MethodSample accession id
CAGE  SAMD00004687
CollapseLibrary accession numbers

Library idMethodExp. accession idRun accession id
CNhs12572 CAGE DRX008321 DRR009193
CollapseAccession ID Hg19

Library idBAMCTSS
CNhs12572 DRZ000618 DRZ002003
CollapseAccession ID Hg38

Library idBAMCTSS
CNhs12572 DRZ011968 DRZ013353
Download raw sequence, BAM & CTSS
CollapseHg19
FastaBAMCTSS
downloaddownloaddonwload
CollapseHg38
BAMCTSS
downloaddonwload


Relative expression to median (log10)


Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.



Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data



Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data



TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample


JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs12572



FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs12572



de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br> library id: CNhs12572


FANTOM5 (FF) ontology


Direct parent terms


Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data

CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000075 (columnar/cuboidal epithelial cell)
0000066 (epithelial cell)
0002371 (somatic cell)
0000325 (stuff accumulating cell)
0000255 (eukaryotic cell)
0000306 (crystallin accumulating cell)
0002222 (vertebrate lens cell)
0002224 (lens epithelial cell)

UBERON: Anatomy
0000468 (multi-cellular organism)
0000970 (eye)
0000019 (camera-type eye)
0000483 (epithelium)
0000033 (head)
0000479 (tissue)
0004121 (ectoderm-derived structure)
0000064 (organ part)
0010314 (structure with developmental contribution from neural crest)
0000047 (simple eye)
0000062 (organ)
0000475 (organism subdivision)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000063 (organ segment)
0001444 (subdivision of head)
0000477 (anatomical cluster)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0000119 (cell layer)
0000490 (unilaminar epithelium)
0010077 (cuboidal epithelium)
0005389 (transparent eye structure)
0000020 (sense organ)
0010371 (ecto-epithelium)
0007625 (pigment epithelium of eye)
0000484 (simple cuboidal epithelium)
0001032 (sensory system)
0010317 (germ layer / neural crest derived structure)
0000965 (lens of camera-type eye)
0001803 (epithelium of lens)
0004088 (ocular region)
0000153 (anterior region of body)
0007811 (craniocervical region)
0002104 (visual system)
0001801 (anterior segment of eyeball)
0004456 (entire sense organ system)
0001456 (face)
0010230 (eyeball of camera-type eye)

FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
0000085 (human lens epithelial cell sample)

Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
NA