FF:13230-141I8: Difference between revisions
From FANTOM5_SSTAR
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|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|datafreeze_phase=1 | |||
|def= | |def= | ||
|expression_enrichment_score=chr1:170632285..170632309,+!p1@PRRX1!2.03!120.53!PRRX1;;chr12:54410664..54410684,+!p1@HOXC4,p1@HOXC5,p1@HOXC6!1.95!87.91!HOXC5;;chr7:19157248..19157268,-!p1@TWIST1!1.76!150.06!TWIST1;;chr1:170633348..170633399,+!p2@PRRX1!1.73!71.43!PRRX1;;chr9:132427883..132427951,+!p2@PRRX2!1.69!48.08!PRRX2;;chr1:170633262..170633285,+!p3@PRRX1!1.62!46.02!PRRX1;;chr15:57511609..57511651,+!p2@TCF12!1.59!63.18!TCF12;;chr12:54402745..54402788,+!p1@HOXC8!1.51!31.59!HOXC8;;chr2:239756671..239756732,+!p1@TWIST2!1.49!93.75!TWIST2;;chr19:13134772..13134822,+!p2@NFIX!1.48!42.92!NFIX;;chr9:132427972..132428056,+!p1@PRRX2!1.48!38.12!PRRX2;;chr1:170632477..170632506,+!p6@PRRX1!1.46!28.16!PRRX1;;chr11:46299199..46299233,+!p1@CREB3L1!1.45!137.01!CREB3L1;;chr12:54393880..54393962,+!p1@HOXC9!1.45!27.47!HOXC9;;chr1:170632959..170632987,+!p4@PRRX1!1.42!27.82!PRRX1;;chr17:1959369..1959388,+!p2@HIC1!1.40!62.84!HIC1;;chr10:119303078..119303169,+!p2@EMX2!1.38!23.01!EMX2;;chr1:170633058..170633084,+!p5@PRRX1!1.36!21.98!PRRX1;;chr12:54410639..54410659,+!p2@HOXC4,p2@HOXC5,p2@HOXC6!1.33!20.26!HOXC5;;chr2:119605214..119605230,-!p1@EN1!1.27!17.51!EN1;;chr10:131762504..131762555,-!p1@EBF3!1.24!16.48!EBF3;;chr2:239756739..239756755,+!p2@TWIST2!1.22!26.78!TWIST2;;chr7:15726296..15726315,-!p1@MEOX2!1.20!14.77!MEOX2;;chr11:46299539..46299620,+!p2@CREB3L1!1.18!24.04!CREB3L1;;chr1:170632723..170632739,+!p8@PRRX1!1.18!14.08!PRRX1;;chr8:25902876..25902936,-!p1@EBF2!1.17!13.74!EBF2;;chr4:174450089..174450153,-!p2@HAND2!1.14!12.71!HAND2;;chr1:170632683..170632696,+!p12@PRRX1!1.10!11.68!PRRX1;;chr1:170632439..170632465,+!p11@PRRX1!1.08!10.99!PRRX1;;chr4:174451370..174451387,-!p1@HAND2!1.08!10.99!HAND2;;chr6:1312325..1312340,+!p1@FOXQ1!1.07!17.51!FOXQ1;;chr5:72744594..72744609,-!p1@FOXD1!1.06!48.42!FOXD1;;chrY:21906594..21906622,-!p1@KDM5D!1.05!10.30!KDM5D;;chr12:54378923..54378966,+!p1@HOXC10!1.04!9.96!HOXC10;;chr12:54379029..54379057,+!p2@HOXC10!1.04!9.96!HOXC10;;chr8:49833948..49833973,-!p2@SNAI2!1.03!63.18!SNAI2;;chr12:54402790..54402805,+!p2@HOXC8!1.03!9.62!HOXC8;;chr6:45296048..45296082,+!p1@RUNX2!1.02!10.99!RUNX2;;chr18:53068911..53068935,-!p4@TCF4!1.02!10.65!TCF4;;chr7:19157043..19157088,-!p2@TWIST1!1.01!23.35!TWIST1;;chr14:24837368..24837401,+!p1@NFATC4!1.01!21.98!NFATC4;;chr17:46682321..46682362,-!p1@HOXB6!1.01!9.27!HOXB6;;chr12:53614115..53614154,-!p1@RARG!1.00!49.11!RARG;;chr1:170632250..170632277,+!p7@PRRX1!1.00!8.93!PRRX1;;chr8:49833978..49833996,-!p1@SNAI2!0.98!179.60!SNAI2;;chr6:1389789..1389821,+!p1@FOXF2!0.98!12.02!FOXF2;;chr7:27192185..27192209,-!p1@HOXA3!0.98!8.58!HOXA3;;chr1:170632137..170632172,+!p10@PRRX1!0.97!8.24!PRRX1;;chr10:119302645..119302712,+!p3@EMX2!0.97!8.24!EMX2;;chr5:321810..321877,+!p1@AHRR!0.96!26.44!AHRR;;chr10:119302508..119302559,+!p5@EMX2!0.95!7.90!EMX2;;chr7:44143925..44143970,+!p1@AEBP1!0.93!172.73!AEBP1;;chr19:13134457..13134462,+!p5@NFIX!0.93!13.74!NFIX;;chr15:57511589..57511608,+!p4@TCF12!0.93!7.55!TCF12;;chr19:50432453..50432468,+!p1@ATF5!0.92!428.21!ATF5;;chr8:77593474..77593612,+!p1@ZFHX4!0.92!31.94!ZFHX4;;chr18:72922743..72922761,+!p3@TSHZ1!0.92!25.07!TSHZ1;;chr7:15726243..15726293,-!p2@MEOX2!0.91!7.21!MEOX2;;chr2:176994408..176994492,+!p1@HOXD8!0.91!7.21!HOXD8;;chr17:1958388..1958404,+!p1@HIC1!0.90!46.70!HIC1;;chr5:158526917..158526932,-!p1@EBF1!0.90!17.86!EBF1;;chr5:142780237..142780261,-!p7@NR3C1!0.90!6.87!NR3C1;;chr4:111558135..111558198,-!p2@PITX2!0.90!6.87!PITX2;;chr18:22932080..22932170,-!p1@ZNF521!0.89!30.22!ZNF521;;chr7:42276787..42276815,-!p1@GLI3!0.88!18.54!GLI3;;chr16:54320646..54320672,-!p2@IRX3!0.88!10.30!IRX3;;chr15:37390482..37390572,-!p7@MEIS2!0.88!9.27!MEIS2;;chr14:61116183..61116208,-!p1@SIX1!0.87!25.75!SIX1;;chr1:170632762..170632786,+!p13@PRRX1!0.86!6.18!PRRX1;;chr17:46621937..46621966,-!p2@HOXB2!0.85!17.17!HOXB2;;chr17:46687959..46688007,-!p2@HOXB7!0.83!8.24!HOXB7;;chr5:158526459..158526481,-!p2@EBF1!0.83!7.90!EBF1;;chr19:13135582..13135600,+!p3@NFIX!0.83!5.84!NFIX;;chr19:47523058..47523114,+!p1@NPAS1!0.83!5.84!NPAS1;;chr1:170632310..170632321,+!p15@PRRX1!0.83!5.84!PRRX1;;chr12:54380404..54380433,+!p3@HOXC10!0.83!5.84!HOXC10;;chr10:119302232..119302265,+!p1@EMX2!0.81!5.49!EMX2;;chr12:54410948..54410992,+!p3@HOXC5!0.81!5.49!HOXC5;;chr17:46132044..46132080,+!p4@NFE2L1!0.81!5.49!NFE2L1;;chr2:19558373..19558392,-!p1@OSR1!0.80!15.45!OSR1;;chr5:2751762..2751784,-!p1@IRX2!0.79!5.15!IRX2;;chr1:170632115..170632136,+!p9@PRRX1!0.79!5.15!PRRX1;;chr1:170632647..170632659,+!p17@PRRX1!0.79!5.15!PRRX1;;chr1:158979792..158979814,+!p2@IFI16!0.78!52.88!IFI16;;chr2:208030647..208030689,-!p1@KLF7!0.78!45.67!KLF7;;chr1:23696308..23696339,-!p2@ZNF436!0.78!11.33!ZNF436;;chr19:13106214..13106382,+!p1@NFIX!0.77!125.00!NFIX;;chr10:77161504..77161530,-!p1@ZNF503!0.77!71.08!ZNF503;;chr16:54320617..54320643,-!p3@IRX3!0.77!6.52!IRX3;;chr8:99956662..99956684,+!p1@OSR2!0.76!7.55!OSR2;;chr7:27205136..27205164,-!p1@HOXA9!0.76!4.81!HOXA9;;chr16:31076332..31076388,-!p3@ZNF668!0.76!4.81!ZNF668;;chr19:13135386..13135435,+!p4@NFIX!0.76!4.81!NFIX;;chr10:31610110..31610159,+!p2@ZEB1!0.76!4.81!ZEB1;;chr12:54402729..54402743,+!p3@HOXC8!0.76!4.81!HOXC8;;chr1:170632907..170632916,+!p22@PRRX1!0.76!4.81!PRRX1;;chr1:158979872..158979898,+!p3@IFI16!0.75!15.45!IFI16;;chr7:44143978..44143989,+!p2@AEBP1!0.75!8.93!AEBP1;;chr16:54320101..54320125,-!p4@IRX3!0.75!6.87!IRX3;;chr5:142780189..142780223,-!p6@NR3C1!0.74!4.46!NR3C1;;chr7:27196267..27196311,-!p1@HOXA7!0.74!4.46!HOXA7;;chr7:27205106..27205134,-!p2@HOXA9!0.74!4.46!HOXA9;;chr2:102091566..102091581,-!p1@RFX8!0.74!4.46!RFX8;;chr2:119604456..119604501,-!p2@EN1!0.74!4.46!EN1;;chr2:177001290..177001315,+!p1@HOXD3!0.74!4.46!HOXD3;;chr4:111544219..111544240,-!p1@PITX2!0.74!4.46!PITX2;;chr1:170632867..170632878,+!p21@PRRX1!0.74!4.46!PRRX1;;chr10:63809013..63809041,+!p3@ARID5B!0.73!27.13!ARID5B;;chr2:85980951..85981004,+!p1@ATOH8!0.73!7.55!ATOH8;;chr17:46688334..46688385,-!p1@HOXB7!0.73!6.52!HOXB7;;chr20:30193083..30193098,+!p1@ID1!0.72!389.41!ID1;;chr9:110252035..110252057,-!p1@KLF4!0.72!75.89!KLF4;;chr18:72922811..72922827,+!p1@TSHZ1!0.72!23.69!TSHZ1;;chr11:65687362..65687436,+!p3@DRAP1!0.71!20.95!DRAP1;;chr5:133450365..133450444,+!p1@TCF7!0.71!20.95!TCF7;;chr7:44143997..44144008,+!p3@AEBP1!0.71!5.49!AEBP1;;chr1:170633245..170633256,+!p14@PRRX1!0.71!4.12!PRRX1;;chr2:85981107..85981120,+!p3@ATOH8!0.71!4.12!ATOH8;;chrY:2803415..2803468,+!p1@ZFY!0.71!4.12!ZFY;;chr12:66218598..66218645,+!p2@HMGA2!0.70!20.95!HMGA2;;chr4:4861385..4861398,+!p1@MSX1!0.70!13.05!MSX1;;chr20:51588873..51588953,+!p1@TSHZ2!0.70!5.49!TSHZ2;;chr1:23696448..23696453,-!p5@ZNF436!0.70!5.15!ZNF436;;chr10:63809106..63809127,+!p1@ARID5B!0.69!59.75!ARID5B;;chr8:106330656..106330684,+!p1@ZFPM2!0.69!11.33!ZFPM2;;chr15:37390850..37390909,-!p3@MEIS2!0.69!8.24!MEIS2;;chr11:65686802..65686818,+!p6@DRAP1!0.69!7.21!DRAP1;;chr15:96876966..96877017,+!p12@NR2F2!0.69!5.84!NR2F2;;chr11:46299186..46299195,+!p3@CREB3L1!0.69!4.46!CREB3L1;;chr20:39317868..39317884,-!p1@MAFB!0.68!51.85!MAFB;;chr3:150126759..150126784,+!p2@TSC22D2!0.68!19.57!TSC22D2;;chr10:77161133..77161176,-!p3@ZNF503!0.68!8.93!ZNF503;;chr15:42749722..42749739,-!p2@ZFP106!0.68!7.21!ZFP106;;chr19:45260775..45260838,+!p5@BCL3!0.68!5.15!BCL3;;chr17:46675558..46675577,-!p2@HOXB6!0.68!3.78!HOXB6;;chr10:63853436..63853442,+!p4@ARID5B!0.67!22.66!ARID5B;;chr11:65686732..65686756,+!p2@DRAP1!0.67!17.51!DRAP1;;chr10:77161650..77161661,-!p4@ZNF503!0.67!5.49!ZNF503;;chr19:13136241..13136258,+!p7@NFIX!0.67!5.15!NFIX;;chr5:72744562..72744573,-!p3@FOXD1!0.67!4.81!FOXD1;;chr14:75894714..75894733,+!p1@JDP2!0.66!117.10!JDP2;;chr6:144329384..144329405,-!p1@PLAGL1!0.66!48.76!PLAGL1;;chr11:65687222..65687240,+!p7@DRAP1!0.66!4.81!DRAP1;;chr8:22550982..22550999,-!p1@EGR3!0.65!10.99!EGR3;;chr15:96874145..96874166,+!p7@NR2F2!0.65!7.21!NR2F2;;chr9:110251836..110251887,-!p4@KLF4!0.65!4.81!KLF4;;chr11:46299443..46299459,+!p4@CREB3L1!0.65!3.43!CREB3L1;;chr12:53625846..53625861,-!p6@RARG!0.65!3.43!RARG;;chr12:54422217..54422239,+!p3@HOXC6!0.65!3.43!HOXC6;;chr1:158979922..158979933,+!p13@IFI16!0.65!3.43!IFI16;;chr1:170632325..170632339,+!p24@PRRX1!0.65!3.43!PRRX1;;chr2:119605253..119605264,-!p5@EN1!0.65!3.43!EN1;;chr3:21792790..21792824,-!p4@ZNF385D!0.65!3.43!ZNF385D;;chr2:8822176..8822196,+!p1@ID2!0.64!558.02!ID2;;chr1:164528410..164528428,+!p1@PBX1!0.64!29.53!PBX1;;chr11:65687158..65687216,+!p4@DRAP1!0.64!22.66!DRAP1;;chr15:37392724..37392757,-!p1@MEIS2!0.64!17.86!MEIS2;;chr3:21792585..21792625,-!p2@ZNF385D!0.64!3.78!ZNF385D;;chr1:23885981..23886002,-!p1@ID3!0.63!678.89!ID3;;chr14:62162258..62162269,+!p2@HIF1A!0.63!37.09!HIF1A;;chr12:115121962..115121987,-!p1@TBX3!0.63!32.28!TBX3;;chr3:114343768..114343822,-!p1@ZBTB20!0.63!16.48!ZBTB20;;chr16:54320675..54320715,-!p1@IRX3!0.63!7.90!IRX3;;chr8:72756667..72756736,-!p2@MSC!0.63!5.49!MSC;;chr9:16870659..16870675,-!p2@BNC2!0.63!4.12!BNC2;;chr16:4366053..4366076,+!p@chr16:4366053..4366076,+!0.62!38.12!GLIS2;;chr14:62162285..62162296,+!p3@HIF1A!0.62!19.23!HIF1A;;chr16:86600426..86600441,+!p1@FOXC2!0.62!8.93!FOXC2;;chr6:144289132..144289134,-!p3@PLAGL1!0.62!8.24!PLAGL1;;chr1:158979851..158979865,+!p5@IFI16!0.62!7.90!IFI16;;chr17:46675420..46675465,-!p3@HOXB6!0.62!3.78!HOXB6;;chr15:96873984..96873999,+!p3@NR2F2!0.61!27.13!NR2F2;;chr1:200379104..200379128,-!p2@ZNF281!0.61!8.58!ZNF281;;chr14:64971014..64971044,+!p4@ZBTB1!0.61!5.49!ZBTB1;;chr15:37391588..37391604,-!p11@MEIS2!0.61!4.12!MEIS2;;chr17:46687935..46687950,-!p3@HOXB7!0.61!3.09!HOXB7;;chr17:46690839..46690884,-!p1@HOXB8!0.61!3.09!HOXB8;;chr1:170633194..170633205,+!p18@PRRX1!0.61!3.09!PRRX1;;chr8:93115584..93115642,-!p5@RUNX1T1!0.61!3.09!RUNX1T1;;chr2:85981073..85981091,+!p5@ATOH8!0.61!3.09!ATOH8;;chr15:96874012..96874042,+!p2@NR2F2!0.60!32.28!NR2F2;;chr5:72744445..72744466,-!p2@FOXD1!0.60!5.49!FOXD1;;chr7:42276822..42276895,-!p2@GLI3!0.59!9.96!GLI3;;chr12:53625966..53626012,-!p2@RARG!0.59!8.93!RARG;;chr15:37392703..37392717,-!p8@MEIS2!0.59!4.46!MEIS2;;chr17:3571863..3571881,-!p1@TAX1BP3!0.58!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| |expression_enrichment_score=chr1:170632285..170632309,+!p1@PRRX1!2.03!120.53!PRRX1;;chr12:54410664..54410684,+!p1@HOXC4,p1@HOXC5,p1@HOXC6!1.95!87.91!HOXC5;;chr7:19157248..19157268,-!p1@TWIST1!1.76!150.06!TWIST1;;chr1:170633348..170633399,+!p2@PRRX1!1.73!71.43!PRRX1;;chr9:132427883..132427951,+!p2@PRRX2!1.69!48.08!PRRX2;;chr1:170633262..170633285,+!p3@PRRX1!1.62!46.02!PRRX1;;chr15:57511609..57511651,+!p2@TCF12!1.59!63.18!TCF12;;chr12:54402745..54402788,+!p1@HOXC8!1.51!31.59!HOXC8;;chr2:239756671..239756732,+!p1@TWIST2!1.49!93.75!TWIST2;;chr19:13134772..13134822,+!p2@NFIX!1.48!42.92!NFIX;;chr9:132427972..132428056,+!p1@PRRX2!1.48!38.12!PRRX2;;chr1:170632477..170632506,+!p6@PRRX1!1.46!28.16!PRRX1;;chr11:46299199..46299233,+!p1@CREB3L1!1.45!137.01!CREB3L1;;chr12:54393880..54393962,+!p1@HOXC9!1.45!27.47!HOXC9;;chr1:170632959..170632987,+!p4@PRRX1!1.42!27.82!PRRX1;;chr17:1959369..1959388,+!p2@HIC1!1.40!62.84!HIC1;;chr10:119303078..119303169,+!p2@EMX2!1.38!23.01!EMX2;;chr1:170633058..170633084,+!p5@PRRX1!1.36!21.98!PRRX1;;chr12:54410639..54410659,+!p2@HOXC4,p2@HOXC5,p2@HOXC6!1.33!20.26!HOXC5;;chr2:119605214..119605230,-!p1@EN1!1.27!17.51!EN1;;chr10:131762504..131762555,-!p1@EBF3!1.24!16.48!EBF3;;chr2:239756739..239756755,+!p2@TWIST2!1.22!26.78!TWIST2;;chr7:15726296..15726315,-!p1@MEOX2!1.20!14.77!MEOX2;;chr11:46299539..46299620,+!p2@CREB3L1!1.18!24.04!CREB3L1;;chr1:170632723..170632739,+!p8@PRRX1!1.18!14.08!PRRX1;;chr8:25902876..25902936,-!p1@EBF2!1.17!13.74!EBF2;;chr4:174450089..174450153,-!p2@HAND2!1.14!12.71!HAND2;;chr1:170632683..170632696,+!p12@PRRX1!1.10!11.68!PRRX1;;chr1:170632439..170632465,+!p11@PRRX1!1.08!10.99!PRRX1;;chr4:174451370..174451387,-!p1@HAND2!1.08!10.99!HAND2;;chr6:1312325..1312340,+!p1@FOXQ1!1.07!17.51!FOXQ1;;chr5:72744594..72744609,-!p1@FOXD1!1.06!48.42!FOXD1;;chrY:21906594..21906622,-!p1@KDM5D!1.05!10.30!KDM5D;;chr12:54378923..54378966,+!p1@HOXC10!1.04!9.96!HOXC10;;chr12:54379029..54379057,+!p2@HOXC10!1.04!9.96!HOXC10;;chr8:49833948..49833973,-!p2@SNAI2!1.03!63.18!SNAI2;;chr12:54402790..54402805,+!p2@HOXC8!1.03!9.62!HOXC8;;chr6:45296048..45296082,+!p1@RUNX2!1.02!10.99!RUNX2;;chr18:53068911..53068935,-!p4@TCF4!1.02!10.65!TCF4;;chr7:19157043..19157088,-!p2@TWIST1!1.01!23.35!TWIST1;;chr14:24837368..24837401,+!p1@NFATC4!1.01!21.98!NFATC4;;chr17:46682321..46682362,-!p1@HOXB6!1.01!9.27!HOXB6;;chr12:53614115..53614154,-!p1@RARG!1.00!49.11!RARG;;chr1:170632250..170632277,+!p7@PRRX1!1.00!8.93!PRRX1;;chr8:49833978..49833996,-!p1@SNAI2!0.98!179.60!SNAI2;;chr6:1389789..1389821,+!p1@FOXF2!0.98!12.02!FOXF2;;chr7:27192185..27192209,-!p1@HOXA3!0.98!8.58!HOXA3;;chr1:170632137..170632172,+!p10@PRRX1!0.97!8.24!PRRX1;;chr10:119302645..119302712,+!p3@EMX2!0.97!8.24!EMX2;;chr5:321810..321877,+!p1@AHRR!0.96!26.44!AHRR;;chr10:119302508..119302559,+!p5@EMX2!0.95!7.90!EMX2;;chr7:44143925..44143970,+!p1@AEBP1!0.93!172.73!AEBP1;;chr19:13134457..13134462,+!p5@NFIX!0.93!13.74!NFIX;;chr15:57511589..57511608,+!p4@TCF12!0.93!7.55!TCF12;;chr19:50432453..50432468,+!p1@ATF5!0.92!428.21!ATF5;;chr8:77593474..77593612,+!p1@ZFHX4!0.92!31.94!ZFHX4;;chr18:72922743..72922761,+!p3@TSHZ1!0.92!25.07!TSHZ1;;chr7:15726243..15726293,-!p2@MEOX2!0.91!7.21!MEOX2;;chr2:176994408..176994492,+!p1@HOXD8!0.91!7.21!HOXD8;;chr17:1958388..1958404,+!p1@HIC1!0.90!46.70!HIC1;;chr5:158526917..158526932,-!p1@EBF1!0.90!17.86!EBF1;;chr5:142780237..142780261,-!p7@NR3C1!0.90!6.87!NR3C1;;chr4:111558135..111558198,-!p2@PITX2!0.90!6.87!PITX2;;chr18:22932080..22932170,-!p1@ZNF521!0.89!30.22!ZNF521;;chr7:42276787..42276815,-!p1@GLI3!0.88!18.54!GLI3;;chr16:54320646..54320672,-!p2@IRX3!0.88!10.30!IRX3;;chr15:37390482..37390572,-!p7@MEIS2!0.88!9.27!MEIS2;;chr14:61116183..61116208,-!p1@SIX1!0.87!25.75!SIX1;;chr1:170632762..170632786,+!p13@PRRX1!0.86!6.18!PRRX1;;chr17:46621937..46621966,-!p2@HOXB2!0.85!17.17!HOXB2;;chr17:46687959..46688007,-!p2@HOXB7!0.83!8.24!HOXB7;;chr5:158526459..158526481,-!p2@EBF1!0.83!7.90!EBF1;;chr19:13135582..13135600,+!p3@NFIX!0.83!5.84!NFIX;;chr19:47523058..47523114,+!p1@NPAS1!0.83!5.84!NPAS1;;chr1:170632310..170632321,+!p15@PRRX1!0.83!5.84!PRRX1;;chr12:54380404..54380433,+!p3@HOXC10!0.83!5.84!HOXC10;;chr10:119302232..119302265,+!p1@EMX2!0.81!5.49!EMX2;;chr12:54410948..54410992,+!p3@HOXC5!0.81!5.49!HOXC5;;chr17:46132044..46132080,+!p4@NFE2L1!0.81!5.49!NFE2L1;;chr2:19558373..19558392,-!p1@OSR1!0.80!15.45!OSR1;;chr5:2751762..2751784,-!p1@IRX2!0.79!5.15!IRX2;;chr1:170632115..170632136,+!p9@PRRX1!0.79!5.15!PRRX1;;chr1:170632647..170632659,+!p17@PRRX1!0.79!5.15!PRRX1;;chr1:158979792..158979814,+!p2@IFI16!0.78!52.88!IFI16;;chr2:208030647..208030689,-!p1@KLF7!0.78!45.67!KLF7;;chr1:23696308..23696339,-!p2@ZNF436!0.78!11.33!ZNF436;;chr19:13106214..13106382,+!p1@NFIX!0.77!125.00!NFIX;;chr10:77161504..77161530,-!p1@ZNF503!0.77!71.08!ZNF503;;chr16:54320617..54320643,-!p3@IRX3!0.77!6.52!IRX3;;chr8:99956662..99956684,+!p1@OSR2!0.76!7.55!OSR2;;chr7:27205136..27205164,-!p1@HOXA9!0.76!4.81!HOXA9;;chr16:31076332..31076388,-!p3@ZNF668!0.76!4.81!ZNF668;;chr19:13135386..13135435,+!p4@NFIX!0.76!4.81!NFIX;;chr10:31610110..31610159,+!p2@ZEB1!0.76!4.81!ZEB1;;chr12:54402729..54402743,+!p3@HOXC8!0.76!4.81!HOXC8;;chr1:170632907..170632916,+!p22@PRRX1!0.76!4.81!PRRX1;;chr1:158979872..158979898,+!p3@IFI16!0.75!15.45!IFI16;;chr7:44143978..44143989,+!p2@AEBP1!0.75!8.93!AEBP1;;chr16:54320101..54320125,-!p4@IRX3!0.75!6.87!IRX3;;chr5:142780189..142780223,-!p6@NR3C1!0.74!4.46!NR3C1;;chr7:27196267..27196311,-!p1@HOXA7!0.74!4.46!HOXA7;;chr7:27205106..27205134,-!p2@HOXA9!0.74!4.46!HOXA9;;chr2:102091566..102091581,-!p1@RFX8!0.74!4.46!RFX8;;chr2:119604456..119604501,-!p2@EN1!0.74!4.46!EN1;;chr2:177001290..177001315,+!p1@HOXD3!0.74!4.46!HOXD3;;chr4:111544219..111544240,-!p1@PITX2!0.74!4.46!PITX2;;chr1:170632867..170632878,+!p21@PRRX1!0.74!4.46!PRRX1;;chr10:63809013..63809041,+!p3@ARID5B!0.73!27.13!ARID5B;;chr2:85980951..85981004,+!p1@ATOH8!0.73!7.55!ATOH8;;chr17:46688334..46688385,-!p1@HOXB7!0.73!6.52!HOXB7;;chr20:30193083..30193098,+!p1@ID1!0.72!389.41!ID1;;chr9:110252035..110252057,-!p1@KLF4!0.72!75.89!KLF4;;chr18:72922811..72922827,+!p1@TSHZ1!0.72!23.69!TSHZ1;;chr11:65687362..65687436,+!p3@DRAP1!0.71!20.95!DRAP1;;chr5:133450365..133450444,+!p1@TCF7!0.71!20.95!TCF7;;chr7:44143997..44144008,+!p3@AEBP1!0.71!5.49!AEBP1;;chr1:170633245..170633256,+!p14@PRRX1!0.71!4.12!PRRX1;;chr2:85981107..85981120,+!p3@ATOH8!0.71!4.12!ATOH8;;chrY:2803415..2803468,+!p1@ZFY!0.71!4.12!ZFY;;chr12:66218598..66218645,+!p2@HMGA2!0.70!20.95!HMGA2;;chr4:4861385..4861398,+!p1@MSX1!0.70!13.05!MSX1;;chr20:51588873..51588953,+!p1@TSHZ2!0.70!5.49!TSHZ2;;chr1:23696448..23696453,-!p5@ZNF436!0.70!5.15!ZNF436;;chr10:63809106..63809127,+!p1@ARID5B!0.69!59.75!ARID5B;;chr8:106330656..106330684,+!p1@ZFPM2!0.69!11.33!ZFPM2;;chr15:37390850..37390909,-!p3@MEIS2!0.69!8.24!MEIS2;;chr11:65686802..65686818,+!p6@DRAP1!0.69!7.21!DRAP1;;chr15:96876966..96877017,+!p12@NR2F2!0.69!5.84!NR2F2;;chr11:46299186..46299195,+!p3@CREB3L1!0.69!4.46!CREB3L1;;chr20:39317868..39317884,-!p1@MAFB!0.68!51.85!MAFB;;chr3:150126759..150126784,+!p2@TSC22D2!0.68!19.57!TSC22D2;;chr10:77161133..77161176,-!p3@ZNF503!0.68!8.93!ZNF503;;chr15:42749722..42749739,-!p2@ZFP106!0.68!7.21!ZFP106;;chr19:45260775..45260838,+!p5@BCL3!0.68!5.15!BCL3;;chr17:46675558..46675577,-!p2@HOXB6!0.68!3.78!HOXB6;;chr10:63853436..63853442,+!p4@ARID5B!0.67!22.66!ARID5B;;chr11:65686732..65686756,+!p2@DRAP1!0.67!17.51!DRAP1;;chr10:77161650..77161661,-!p4@ZNF503!0.67!5.49!ZNF503;;chr19:13136241..13136258,+!p7@NFIX!0.67!5.15!NFIX;;chr5:72744562..72744573,-!p3@FOXD1!0.67!4.81!FOXD1;;chr14:75894714..75894733,+!p1@JDP2!0.66!117.10!JDP2;;chr6:144329384..144329405,-!p1@PLAGL1!0.66!48.76!PLAGL1;;chr11:65687222..65687240,+!p7@DRAP1!0.66!4.81!DRAP1;;chr8:22550982..22550999,-!p1@EGR3!0.65!10.99!EGR3;;chr15:96874145..96874166,+!p7@NR2F2!0.65!7.21!NR2F2;;chr9:110251836..110251887,-!p4@KLF4!0.65!4.81!KLF4;;chr11:46299443..46299459,+!p4@CREB3L1!0.65!3.43!CREB3L1;;chr12:53625846..53625861,-!p6@RARG!0.65!3.43!RARG;;chr12:54422217..54422239,+!p3@HOXC6!0.65!3.43!HOXC6;;chr1:158979922..158979933,+!p13@IFI16!0.65!3.43!IFI16;;chr1:170632325..170632339,+!p24@PRRX1!0.65!3.43!PRRX1;;chr2:119605253..119605264,-!p5@EN1!0.65!3.43!EN1;;chr3:21792790..21792824,-!p4@ZNF385D!0.65!3.43!ZNF385D;;chr2:8822176..8822196,+!p1@ID2!0.64!558.02!ID2;;chr1:164528410..164528428,+!p1@PBX1!0.64!29.53!PBX1;;chr11:65687158..65687216,+!p4@DRAP1!0.64!22.66!DRAP1;;chr15:37392724..37392757,-!p1@MEIS2!0.64!17.86!MEIS2;;chr3:21792585..21792625,-!p2@ZNF385D!0.64!3.78!ZNF385D;;chr1:23885981..23886002,-!p1@ID3!0.63!678.89!ID3;;chr14:62162258..62162269,+!p2@HIF1A!0.63!37.09!HIF1A;;chr12:115121962..115121987,-!p1@TBX3!0.63!32.28!TBX3;;chr3:114343768..114343822,-!p1@ZBTB20!0.63!16.48!ZBTB20;;chr16:54320675..54320715,-!p1@IRX3!0.63!7.90!IRX3;;chr8:72756667..72756736,-!p2@MSC!0.63!5.49!MSC;;chr9:16870659..16870675,-!p2@BNC2!0.63!4.12!BNC2;;chr16:4366053..4366076,+!p@chr16:4366053..4366076,+!0.62!38.12!GLIS2;;chr14:62162285..62162296,+!p3@HIF1A!0.62!19.23!HIF1A;;chr16:86600426..86600441,+!p1@FOXC2!0.62!8.93!FOXC2;;chr6:144289132..144289134,-!p3@PLAGL1!0.62!8.24!PLAGL1;;chr1:158979851..158979865,+!p5@IFI16!0.62!7.90!IFI16;;chr17:46675420..46675465,-!p3@HOXB6!0.62!3.78!HOXB6;;chr15:96873984..96873999,+!p3@NR2F2!0.61!27.13!NR2F2;;chr1:200379104..200379128,-!p2@ZNF281!0.61!8.58!ZNF281;;chr14:64971014..64971044,+!p4@ZBTB1!0.61!5.49!ZBTB1;;chr15:37391588..37391604,-!p11@MEIS2!0.61!4.12!MEIS2;;chr17:46687935..46687950,-!p3@HOXB7!0.61!3.09!HOXB7;;chr17:46690839..46690884,-!p1@HOXB8!0.61!3.09!HOXB8;;chr1:170633194..170633205,+!p18@PRRX1!0.61!3.09!PRRX1;;chr8:93115584..93115642,-!p5@RUNX1T1!0.61!3.09!RUNX1T1;;chr2:85981073..85981091,+!p5@ATOH8!0.61!3.09!ATOH8;;chr15:96874012..96874042,+!p2@NR2F2!0.60!32.28!NR2F2;;chr5:72744445..72744466,-!p2@FOXD1!0.60!5.49!FOXD1;;chr7:42276822..42276895,-!p2@GLI3!0.59!9.96!GLI3;;chr12:53625966..53626012,-!p2@RARG!0.59!8.93!RARG;;chr15:37392703..37392717,-!p8@MEIS2!0.59!4.46!MEIS2;;chr17:3571863..3571881,-!p1@TAX1BP3!0.58!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2;;chr3:69788576..69788648,+!p1@MITF!0.22!7.21!MITF;;chr19:31840313..31840380,-!p1@TSHZ3!0.22!3.09!TSHZ3;;chr3:114819124..114819200,-!p3@ZBTB20!0.22!2.75!ZBTB20;;chr20:3388579..3388619,-!p3@C20orf194!0.22!2.75!C20orf194;;chr9:14314522..14314556,-!p3@NFIB!0.22!2.75!NFIB;;chr3:23986748..23986761,+!p3@NR1D2!0.22!2.40!NR1D2;;chr5:139487608..139487663,+!p3@PURA!0.22!2.40!PURA;;chr19:11877805..11877832,+!p2@ZNF441!0.22!1.72!ZNF441;;chr1:205592857..205592880,-!p6@ELK4!0.22!1.72!ELK4;;chr20:50808252..50808264,-!p4@ZFP64!0.22!1.72!ZFP64;;chr20:48807648..48807671,+!p9@CEBPB!0.22!1.37!CEBPB;;chr19:3366625..3366629,+!p4@NFIC!0.22!1.37!NFIC;;chr17:40719165..40719168,+!p4@MLX!0.22!1.03!MLX;;chr18:42260030..42260055,+!p3@SETBP1!0.22!1.03!SETBP1;;chr18:56530573..56530591,+!p9@ZNF532!0.22!1.03!ZNF532;;chr19:35759387..35759398,+!p6@USF2!0.22!1.03!USF2;;chr8:116681275..116681290,-!p11@TRPS1!0.22!1.03!TRPS1;;chr8:72756023..72756055,-!p6@MSC!0.22!1.03!MSC;;chr10:22022947..22022965,+!p7@MLLT10!0.22!1.03!MLLT10;;chr1:43148059..43148108,+!p1@YBX1!0.21!94.09!YBX1;;chr3:52008016..52008071,-!p1@ABHD14A-ACY1,p1@ABHD14B,p1@PCBP4!0.21!85.16!PCBP4;;chr19:7580944..7581031,+!p1@ZNF358!0.21!43.95!ZNF358;;chr2:217277169..217277266,+!p1@SMARCAL1!0.21!14.77!SMARCAL1;;chr12:27485823..27485868,+!p2@ARNTL2!0.21!5.15!ARNTL2;;chr9:2017063..2017144,+!p4@SMARCA2!0.21!3.78!SMARCA2;;chr3:150126706..150126754,+!p5@TSC22D2!0.21!3.78!TSC22D2;;chr6:41040923..41040952,+!p2@NFYA!0.21!3.09!NFYA;;chr20:306051..306096,+!p3@SOX12!0.21!3.09!SOX12;;chr19:58951496..58951539,-!p1@ZNF132!0.21!2.75!ZNF132;;chr17:61919985..61920012,-!p3@SMARCD2!0.21!2.75!SMARCD2;;chr12:133758115..133758138,+!p3@ZNF268!0.21!2.75!ZNF268;;chr13:45151403..45151433,-!p5@TSC22D1!0.21!2.40!TSC22D1;;chr12:12764947..12764986,+!p2@CREBL2!0.21!2.06!CREBL2;;chr2:242576946..242576996,-!p4@THAP4!0.21!2.06!THAP4;;chr20:25677399..25677433,-!p3@ZNF337!0.21!2.06!ZNF337;;chr8:116681150..116681164,-!p5@TRPS1!0.21!2.06!TRPS1;;chr6:12012249..12012266,+!p5@HIVEP1!0.21!1.72!HIVEP1;;chr7:113726357..113726443,+!p1@FOXP2!0.21!1.72!FOXP2;;chr7:137564014..137564042,-!p8@CREB3L2!0.21!1.72!CREB3L2;;chr2:28616316..28616327,+!p5@FOSL2!0.21!1.72!FOSL2;;chr7:77428227..77428242,+!p3@PHTF2!0.21!1.37!PHTF2;;chr12:56401175..56401225,+!p3@IKZF4!0.21!1.37!IKZF4;;chr9:88969226..88969237,-!p4@ZCCHC6!0.21!1.37!ZCCHC6;;chr9:2029144..2029164,+!p10@SMARCA2!0.21!1.03!SMARCA2;;chr16:30798476..30798483,-!p2@ZNF629!0.21!1.03!ZNF629;;chr17:2304082..2304103,-!p5@MNT!0.21!1.03!MNT;;chr22:30163056..30163067,-!p3@ZMAT5!0.21!1.03!ZMAT5;;chr14:24630465..24630531,+!p1@IRF9!0.20!54.94!IRF9;;chr16:29817789..29817838,+!p2@MAZ!0.20!18.89!MAZ;;chr22:30162924..30163005,-!p1@ZMAT5!0.20!17.17!ZMAT5;;chr12:96588143..96588185,+!p1@ELK3!0.20!16.83!ELK3;;chr21:44394645..44394737,+!p1@PKNOX1!0.20!11.33!PKNOX1;;chrX:152599604..152599626,+!p1@ZNF275!0.20!10.30!ZNF275;;chr19:35264089..35264146,-!p1@ZNF599!0.20!6.52!ZNF599;;chrX:47509994..47510008,-!p2@ELK1!0.20!5.15!ELK1;;chr8:116681221..116681236,-!p3@TRPS1!0.20!3.43!TRPS1;;chr16:29817231..29817290,+!p10@MAZ!0.20!3.43!MAZ;;chr19:19516507..19516539,+!p7@GATAD2A!0.20!3.43!GATAD2A;;chr10:114710244..114710257,+!p3@TCF7L2!0.20!3.09!TCF7L2;;chr12:27485762..27485776,+!p3@ARNTL2!0.20!3.09!ARNTL2;;chr12:96588368..96588394,+!p3@ELK3!0.20!3.09!ELK3;;chr18:51750928..51750942,-!p4@MBD2!0.20!2.75!MBD2;; 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Revision as of 18:31, 29 June 2012
Name: | mesenchymal stem cells (adipose derived), adipogenic induction, 00hr00min, biol_rep2 |
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Species: | Human (Homo sapiens) |
Library ID: | {{{library_id}}} |
Sample type: | {{{sample_category}}} |
Genomic View: | UCSC |
CAGEd-oPOSSUM: | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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Download raw sequence, BAM & CTSS | ||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
no result for this sample
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13420
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13420
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.396 |
10 | 10 | 0.364 |
100 | 100 | 0.691 |
101 | 101 | 0.672 |
102 | 102 | 0.166 |
103 | 103 | 0.363 |
104 | 104 | 0.724 |
105 | 105 | 0.332 |
106 | 106 | 0.456 |
107 | 107 | 0.183 |
108 | 108 | 0.2 |
109 | 109 | 0.766 |
11 | 11 | 0.522 |
110 | 110 | 0.164 |
111 | 111 | 0.94 |
112 | 112 | 0.158 |
113 | 113 | 0.016 |
114 | 114 | 0.231 |
115 | 115 | 0.0789 |
116 | 116 | 0.0743 |
117 | 117 | 0.556 |
118 | 118 | 0.536 |
119 | 119 | 0.879 |
12 | 12 | 0.679 |
120 | 120 | 0.621 |
121 | 121 | 0.832 |
122 | 122 | 0.00746 |
123 | 123 | 0.0102 |
124 | 124 | 0.357 |
125 | 125 | 0.729 |
126 | 126 | 0.987 |
127 | 127 | 0.827 |
128 | 128 | 0.345 |
129 | 129 | 0.829 |
13 | 13 | 0.615 |
130 | 130 | 0.728 |
131 | 131 | 0.502 |
132 | 132 | 0.282 |
133 | 133 | 0.579 |
134 | 134 | 0.0569 |
135 | 135 | 0.807 |
136 | 136 | 0.308 |
137 | 137 | 0.289 |
138 | 138 | 0.443 |
139 | 139 | 0.898 |
14 | 14 | 0.248 |
140 | 140 | 0.565 |
141 | 141 | 0.66 |
142 | 142 | 0.812 |
143 | 143 | 0.878 |
144 | 144 | 0.2 |
145 | 145 | 0.512 |
146 | 146 | 0.663 |
147 | 147 | 0.304 |
148 | 148 | 0.558 |
149 | 149 | 0.00849 |
15 | 15 | 0.559 |
150 | 150 | 0.255 |
151 | 151 | 0.748 |
152 | 152 | 0.219 |
153 | 153 | 0.139 |
154 | 154 | 0.865 |
155 | 155 | 0.00209 |
156 | 156 | 0.793 |
157 | 157 | 0.463 |
158 | 158 | 0.011 |
159 | 159 | 0.281 |
16 | 16 | 0.0315 |
160 | 160 | 0.189 |
161 | 161 | 0.885 |
162 | 162 | 0.355 |
163 | 163 | 0.876 |
164 | 164 | 0.135 |
165 | 165 | 0.945 |
166 | 166 | 0.0642 |
167 | 167 | 0.977 |
168 | 168 | 0.772 |
169 | 169 | 0.0127 |
17 | 17 | 0.592 |
18 | 18 | 0.0992 |
19 | 19 | 0.00312 |
2 | 2 | 0.244 |
20 | 20 | 0.372 |
21 | 21 | 0.0101 |
22 | 22 | 0.292 |
23 | 23 | 0.643 |
24 | 24 | 0.297 |
25 | 25 | 0.355 |
26 | 26 | 0.154 |
27 | 27 | 0.696 |
28 | 28 | 0.165 |
29 | 29 | 0.515 |
3 | 3 | 0.309 |
30 | 30 | 0.215 |
31 | 31 | 0.5 |
32 | 32 | 8.20912e-14 |
33 | 33 | 0.94 |
34 | 34 | 0.612 |
35 | 35 | 0.997 |
36 | 36 | 0.0833 |
37 | 37 | 0.0574 |
38 | 38 | 0.643 |
39 | 39 | 0.12 |
4 | 4 | 0.277 |
40 | 40 | 0.238 |
41 | 41 | 0.353 |
42 | 42 | 0.846 |
43 | 43 | 0.428 |
44 | 44 | 0.125 |
45 | 45 | 0.928 |
46 | 46 | 0.275 |
47 | 47 | 0.994 |
48 | 48 | 0.743 |
49 | 49 | 0.924 |
5 | 5 | 0.9 |
50 | 50 | 0.78 |
51 | 51 | 0.862 |
52 | 52 | 0.865 |
53 | 53 | 0.126 |
54 | 54 | 0.582 |
55 | 55 | 0.146 |
56 | 56 | 0.878 |
57 | 57 | 0.95 |
58 | 58 | 0.423 |
59 | 59 | 0.0926 |
6 | 6 | 0.734 |
60 | 60 | 0.833 |
61 | 61 | 0.923 |
62 | 62 | 0.796 |
63 | 63 | 0.432 |
64 | 64 | 0.946 |
65 | 65 | 0.448 |
66 | 66 | 0.211 |
67 | 67 | 0.342 |
68 | 68 | 0.377 |
69 | 69 | 0.672 |
7 | 7 | 0.29 |
70 | 70 | 0.277 |
71 | 71 | 0.172 |
72 | 72 | 0.607 |
73 | 73 | 0.124 |
74 | 74 | 0.115 |
75 | 75 | 0.443 |
76 | 76 | 0.563 |
77 | 77 | 0.0117 |
78 | 78 | 0.52 |
79 | 79 | 0.00322 |
8 | 8 | 0.121 |
80 | 80 | 0.844 |
81 | 81 | 0.4 |
82 | 82 | 0.382 |
83 | 83 | 0.699 |
84 | 84 | 0.762 |
85 | 85 | 0.424 |
86 | 86 | 0.397 |
87 | 87 | 0.133 |
88 | 88 | 0.579 |
89 | 89 | 0.047 |
9 | 9 | 0.532 |
90 | 90 | 0.83 |
91 | 91 | 0.771 |
92 | 92 | 0.338 |
93 | 93 | 0.225 |
94 | 94 | 0.566 |
95 | 95 | 0.79 |
96 | 96 | 0.686 |
97 | 97 | 0.832 |
98 | 98 | 0.983 |
99 | 99 | 0.0352 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13420
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000690 human mesenchymal stem cells adipose derived, 0 minutes after adipogenic induction sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000723 (somatic stem cell)
0000048 (multi fate stem cell)
0000548 (animal cell)
0000034 (stem cell)
0002320 (connective tissue cell)
0002371 (somatic cell)
0000219 (motile cell)
0000325 (stuff accumulating cell)
0000134 (mesenchymal cell)
0000255 (eukaryotic cell)
0000136 (fat cell)
0002570 (mesenchymal stem cell of adipose)
UBERON: Anatomy
0001013 (adipose tissue)
0002384 (connective tissue)
0000479 (tissue)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0001062 (anatomical entity)
FF: FANTOM5
NA
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
NA