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MCL coexpression mm9:281: Difference between revisions

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|gostat_on_MCL_coexpression=GO:0045211;postsynaptic membrane;0.00470690023203389;20355,14806,14802!GO:0005234;extracellular-glutamate-gated ion channel activity;0.00470690023203389;14806,14802!GO:0004970;ionotropic glutamate receptor activity;0.00470690023203389;14806,14802!GO:0044456;synapse part;0.00470690023203389;20355,14806,14802!GO:0030054;cell junction;0.00620867731463551;14806,230959,14802,13527!GO:0005231;excitatory extracellular ligand-gated ion channel activity;0.0139163769570832;14806,14802!GO:0008066;glutamate receptor activity;0.0139163769570832;14806,14802!GO:0016014;dystrobrevin complex;0.01840793294253;13527!GO:0005230;extracellular ligand-gated ion channel activity;0.0235807865386546;14806,14802!GO:0015277;kainate selective glutamate receptor activity;0.026499165811143;14806!GO:0007411;axon guidance;0.026499165811143;20355,14009!GO:0015276;ligand-gated ion channel activity;0.026499165811143;14806,14802!GO:0022834;ligand-gated channel activity;0.026499165811143;14806,14802!GO:0007638;mechanosensory behavior;0.0392283199289765;14009!GO:0015016;[heparan sulfate]-glucosamine N-sulfotransferase activity;0.0392283199289765;83398!
|gostat_on_MCL_coexpression=GO:0045211;postsynaptic membrane;0.00470690023203389;20355,14806,14802!GO:0005234;extracellular-glutamate-gated ion channel activity;0.00470690023203389;14806,14802!GO:0004970;ionotropic glutamate receptor activity;0.00470690023203389;14806,14802!GO:0044456;synapse part;0.00470690023203389;20355,14806,14802!GO:0030054;cell junction;0.00620867731463551;14806,230959,14802,13527!GO:0005231;excitatory extracellular ligand-gated ion channel activity;0.0139163769570832;14806,14802!GO:0008066;glutamate receptor activity;0.0139163769570832;14806,14802!GO:0016014;dystrobrevin complex;0.01840793294253;13527!GO:0005230;extracellular ligand-gated ion channel activity;0.0235807865386546;14806,14802!GO:0015277;kainate selective glutamate receptor activity;0.026499165811143;14806!GO:0007411;axon guidance;0.026499165811143;20355,14009!GO:0015276;ligand-gated ion channel activity;0.026499165811143;14806,14802!GO:0022834;ligand-gated channel activity;0.026499165811143;14806,14802!GO:0007638;mechanosensory behavior;0.0392283199289765;14009!GO:0015016;[heparan sulfate]-glucosamine N-sulfotransferase activity;0.0392283199289765;83398!
|ontology_enrichment_celltype=CL:0000540!1.33e-15!33;CL:0000047!1.33e-15!33;CL:0000031!1.33e-15!33;CL:0000404!1.33e-15!33;CL:0000393!7.73e-13!39;CL:0000211!7.73e-13!39;CL:0000221!1.78e-12!44;CL:0000133!1.78e-12!44;CL:0002319!4.51e-12!43;CL:0000055!2.70e-10!49;CL:0000117!1.83e-09!23;CL:0000337!1.83e-09!23;CL:0000107!1.64e-07!9
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0001017!7.36e-29!73;UBERON:0001016!2.05e-28!75;UBERON:0004121!9.93e-28!95;UBERON:0000924!9.93e-28!95;UBERON:0006601!9.93e-28!95;UBERON:0002346!2.86e-24!64;UBERON:0003075!2.86e-24!64;UBERON:0007284!2.86e-24!64;UBERON:0010371!4.86e-22!73;UBERON:0000073!1.07e-20!54;UBERON:0010314!1.15e-19!92;UBERON:0001049!1.49e-19!52;UBERON:0005068!1.49e-19!52;UBERON:0006241!1.49e-19!52;UBERON:0007135!1.49e-19!52;UBERON:0003056!5.68e-17!49;UBERON:0000955!6.11e-17!47;UBERON:0006238!6.11e-17!47;UBERON:0002616!2.68e-16!46;UBERON:0003080!1.20e-14!40;UBERON:0002020!4.62e-14!34;UBERON:0002780!4.71e-14!39;UBERON:0001890!4.71e-14!39;UBERON:0006240!4.71e-14!39;UBERON:0003528!1.62e-11!29;UBERON:0002791!1.62e-11!29;UBERON:0001893!1.62e-11!29;UBERON:0000468!2.54e-09!333;UBERON:0000956!7.12e-08!21;UBERON:0001869!7.12e-08!21;UBERON:0000203!7.12e-08!21;UBERON:0002619!1.63e-07!17;UBERON:0002410!1.64e-07!9;UBERON:0002021!2.82e-07!10;UBERON:0000411!2.82e-07!10;UBERON:0001950!2.82e-07!10
}}
}}

Revision as of 19:04, 11 October 2012


Phase1 CAGE Peaks

 Short description
Mm9::chr10:4707315..4707330,-p1@Vip
Mm9::chr10:48938780..48938784,-p@chr10:48938780..48938784
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Mm9::chr10:49503296..49503388,-p3@Grik2
Mm9::chr10:49508549..49508575,-p1@Grik2
Mm9::chr12:39507404..39507441,+p4@Etv1
Mm9::chr18:23656049..23656109,+p3@Dtna
Mm9::chr19:10379357..10379444,-p1@Dagla
Mm9::chr19:42506268..42506282,-p1@Crtac1
Mm9::chr3:123393724..123393765,-p2@Ndst3
Mm9::chr3:75361452..75361483,+p1@Serpini1
Mm9::chr4:152857048..152857081,-p1@Ajap1
Mm9::chr4:66007191..66007194,-p@chr4:66007191..66007194
-
Mm9::chr4:66065468..66065490,-p2@Astn2
Mm9::chr4:66065492..66065543,-p1@Astn2
Mm9::chr4:9196485..9196509,+p2@Clvs1
Mm9::chr6:82889553..82889581,-p2@Sema4f
Mm9::chr7:51842709..51842745,+p@chr7:51842709..51842745
+
Mm9::chr7:98691475..98691503,+p12@Dlg2
Mm9::chr7:98691504..98691553,+p5@Dlg2
Mm9::chr7:99473169..99473173,+p@chr7:99473169..99473173
+
Mm9::chr9:4635267..4635271,-p@chr9:4635267..4635271
-
Mm9::chr9:4765243..4765247,-p@chr9:4765243..4765247
-
Mm9::chr9:4795561..4795644,-p3@Gria4
Mm9::chr9:4796022..4796033,-p10@Gria4
Mm9::chr9:4796034..4796066,-p5@Gria4
Mm9::chr9:4796070..4796081,-p9@Gria4
Mm9::chr9:4796141..4796159,-p6@Gria4
Mm9::chr9:4796160..4796195,-p2@Gria4
Mm9::chr9:4796196..4796216,-p4@Gria4
Mm9::chr9:62384753..62384758,-p16@Coro2b


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0045211postsynaptic membrane0.00470690023203389
GO:0005234extracellular-glutamate-gated ion channel activity0.00470690023203389
GO:0004970ionotropic glutamate receptor activity0.00470690023203389
GO:0044456synapse part0.00470690023203389
GO:0030054cell junction0.00620867731463551
GO:0005231excitatory extracellular ligand-gated ion channel activity0.0139163769570832
GO:0008066glutamate receptor activity0.0139163769570832
GO:0016014dystrobrevin complex0.01840793294253
GO:0005230extracellular ligand-gated ion channel activity0.0235807865386546
GO:0015277kainate selective glutamate receptor activity0.026499165811143
GO:0007411axon guidance0.026499165811143
GO:0015276ligand-gated ion channel activity0.026499165811143
GO:0022834ligand-gated channel activity0.026499165811143
GO:0007638mechanosensory behavior0.0392283199289765
GO:0015016[heparan sulfate]-glucosamine N-sulfotransferase activity0.0392283199289765



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
central nervous system7.36e-2973
nervous system2.05e-2875
ectoderm-derived structure9.93e-2895
ectoderm9.93e-2895
presumptive ectoderm9.93e-2895
neurectoderm2.86e-2464
neural plate2.86e-2464
presumptive neural plate2.86e-2464
ecto-epithelium4.86e-2273
regional part of nervous system1.07e-2054
structure with developmental contribution from neural crest1.15e-1992
neural tube1.49e-1952
neural rod1.49e-1952
future spinal cord1.49e-1952
neural keel1.49e-1952
pre-chordal neural plate5.68e-1749
brain6.11e-1747
future brain6.11e-1747
regional part of brain2.68e-1646
anterior neural tube1.20e-1440
gray matter4.62e-1434
regional part of forebrain4.71e-1439
forebrain4.71e-1439
future forebrain4.71e-1439
brain grey matter1.62e-1129
regional part of telencephalon1.62e-1129
telencephalon1.62e-1129
multi-cellular organism2.54e-09333
cerebral cortex7.12e-0821
cerebral hemisphere7.12e-0821
pallium7.12e-0821
regional part of cerebral cortex1.63e-0717
autonomic nervous system1.64e-079
occipital lobe2.82e-0710
visual cortex2.82e-0710
neocortex2.82e-0710


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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