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MCL coexpression mm9:1303

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Phase1 CAGE Peaks

 Short description
Mm9::chr11:72080123..72080142,-p2@Slc13a5
Mm9::chr15:18748419..18748446,+p3@Cdh10
Mm9::chr15:18748455..18748481,+p1@Cdh10
Mm9::chr15:18748708..18748717,+p4@Cdh10
Mm9::chr15:18853092..18853096,+p@chr15:18853092..18853096
+
Mm9::chr6:125095277..125095296,+p3@Iffo1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0015141succinate transmembrane transporter activity0.00160699774110706
GO:0015744succinate transport0.00160699774110706
GO:0006842tricarboxylic acid transport0.00160699774110706
GO:0015137citrate transmembrane transporter activity0.00160699774110706
GO:0015142tricarboxylic acid transmembrane transporter activity0.00160699774110706
GO:0015746citrate transport0.00160699774110706
GO:0005310dicarboxylic acid transmembrane transporter activity0.00602492081764192
GO:0006835dicarboxylic acid transport0.00602492081764192
GO:0046943carboxylic acid transmembrane transporter activity0.0240666654828289
GO:0005342organic acid transmembrane transporter activity0.0240666654828289
GO:0046942carboxylic acid transport0.0240666654828289
GO:0015849organic acid transport0.0240666654828289
GO:0031402sodium ion binding0.0288609803336571
GO:0007156homophilic cell adhesion0.0288609803336571
GO:0006814sodium ion transport0.0358882749621469
GO:0015293symporter activity0.0399306889399139
GO:0015291secondary active transmembrane transporter activity0.0471791609237227
GO:0031420alkali metal ion binding0.0471791609237227



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
central nervous system1.40e-2873
nervous system1.50e-2875
ectoderm-derived structure2.96e-2695
ectoderm2.96e-2695
presumptive ectoderm2.96e-2695
neurectoderm1.53e-2464
neural plate1.53e-2464
presumptive neural plate1.53e-2464
structure with developmental contribution from neural crest8.33e-2292
regional part of nervous system2.08e-2154
ecto-epithelium1.19e-2073
neural tube3.93e-2052
neural rod3.93e-2052
future spinal cord3.93e-2052
neural keel3.93e-2052
pre-chordal neural plate1.27e-1749
brain2.08e-1747
future brain2.08e-1747
regional part of brain8.61e-1746
anterior neural tube2.77e-1540
regional part of forebrain1.10e-1439
forebrain1.10e-1439
future forebrain1.10e-1439
gray matter2.04e-1434
brain grey matter8.38e-1229
regional part of telencephalon8.38e-1229
telencephalon8.38e-1229
cerebral cortex5.75e-0921
cerebral hemisphere5.75e-0921
pallium5.75e-0921
regional part of cerebral cortex5.41e-0817
occipital lobe6.17e-0810
visual cortex6.17e-0810
neocortex6.17e-0810
multi-cellular organism7.83e-07333
autonomic nervous system9.36e-079


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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