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Coexpression cluster:C4432

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Full id: C4432_carcinosarcoma_neuroblastoma_temporal_duodenum_parietal_Neurons_occipital



Phase1 CAGE Peaks

Hg19::chr4:81105065..81105089,+p8@PRDM8
Hg19::chr4:81105091..81105107,+p9@PRDM8
Hg19::chr4:81118647..81118666,+p1@PRDM8


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube6.30e-2557
neural rod6.30e-2557
future spinal cord6.30e-2557
neural keel6.30e-2557
regional part of nervous system6.55e-2594
nervous system6.55e-2594
adult organism5.04e-24115
central nervous system2.38e-2282
regional part of brain3.97e-2159
regional part of forebrain1.32e-1941
forebrain1.32e-1941
future forebrain1.32e-1941
brain3.04e-1969
future brain3.04e-1969
anterior neural tube1.72e-1842
telencephalon1.10e-1634
gray matter1.67e-1634
brain grey matter1.67e-1634
neural plate3.45e-1686
presumptive neural plate3.45e-1686
regional part of cerebral cortex4.35e-1622
regional part of telencephalon4.91e-1633
neurectoderm5.95e-1690
cerebral hemisphere1.33e-1532
neocortex9.51e-1520
cerebral cortex1.36e-1225
pallium1.36e-1225
pre-chordal neural plate1.70e-1161
ectoderm1.84e-11173
presumptive ectoderm1.84e-11173
ectoderm-derived structure2.02e-11169
head2.45e-10123
anterior region of body4.61e-10129
craniocervical region4.61e-10129
tissue1.76e-08787
posterior neural tube1.26e-0715
chordal neural plate1.26e-0715


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.