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Coexpression cluster:C639

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Full id: C639_parietal_embryonic_medial_temporal_cerebellum_skin_spinal



Phase1 CAGE Peaks

Hg19::chrX:73041945..73041959,-p29@XIST
Hg19::chrX:73041988..73042011,-p21@XIST
Hg19::chrX:73047336..73047354,-p20@XIST
Hg19::chrX:73048926..73048955,-p9@XIST
Hg19::chrX:73048958..73048974,-p4@XIST
Hg19::chrX:73049003..73049016,-p13@XIST
Hg19::chrX:73051003..73051017,-p6@XIST
Hg19::chrX:73062712..73062759,-p14@XIST
Hg19::chrX:73062912..73062975,-p5@XIST
Hg19::chrX:73063015..73063028,-p16@XIST
Hg19::chrX:73063126..73063144,-p7@XIST
Hg19::chrX:73069895..73069965,-p@chrX:73069895..73069965
-
Hg19::chrX:73070803..73070814,-p@chrX:73070803..73070814
-
Hg19::chrX:73072534..73072558,-p1@XIST


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube3.22e-2156
neural rod3.22e-2156
future spinal cord3.22e-2156
neural keel3.22e-2156
regional part of nervous system1.58e-1953
regional part of brain1.58e-1953
regional part of forebrain6.79e-1641
forebrain6.79e-1641
anterior neural tube6.79e-1641
future forebrain6.79e-1641
central nervous system7.30e-1581
brain grey matter6.10e-1434
gray matter6.10e-1434
neural plate2.39e-1382
presumptive neural plate2.39e-1382
neurectoderm3.05e-1386
telencephalon6.39e-1334
brain6.42e-1368
future brain6.42e-1368
nervous system7.84e-1389
regional part of telencephalon7.87e-1332
cerebral hemisphere4.32e-1232
adult organism5.51e-12114
ecto-epithelium1.08e-11104
pre-chordal neural plate4.96e-1061
regional part of cerebral cortex5.07e-0922
cerebral cortex6.00e-0925
pallium6.00e-0925
structure with developmental contribution from neural crest2.54e-08132
neocortex5.61e-0820
ectoderm-derived structure1.09e-07171
ectoderm1.09e-07171
presumptive ectoderm1.09e-07171
basal ganglion5.39e-079
nuclear complex of neuraxis5.39e-079
aggregate regional part of brain5.39e-079
collection of basal ganglia5.39e-079
cerebral subcortex5.39e-079
neural nucleus7.55e-079
nucleus of brain7.55e-079
organ8.77e-07503


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
ZNF263#1012784.698195221148967.25281863103391e-050.0011402636233728



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.