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Coexpression cluster:C3727

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Full id: C3727_parietal_small_occipital_Dendritic_temporal_duodenum_CD19



Phase1 CAGE Peaks

Hg19::chr18:52989646..52989657,-p@chr18:52989646..52989657
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Hg19::chr18:52993630..52993631,-p@chr18:52993630..52993631
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Hg19::chr18:53254566..53254567,-p8@TCF4


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
nervous system4.74e-2989
central nervous system5.73e-2781
neural tube1.59e-2456
neural rod1.59e-2456
future spinal cord1.59e-2456
neural keel1.59e-2456
brain3.56e-2368
future brain3.56e-2368
regional part of nervous system4.54e-2353
regional part of brain4.54e-2353
adult organism9.10e-21114
regional part of forebrain1.87e-1941
forebrain1.87e-1941
anterior neural tube1.87e-1941
future forebrain1.87e-1941
neurectoderm3.45e-1886
brain grey matter1.24e-1734
gray matter1.24e-1734
telencephalon3.25e-1734
neural plate6.48e-1782
presumptive neural plate6.48e-1782
regional part of telencephalon1.30e-1632
cerebral hemisphere3.17e-1632
cerebral cortex9.67e-1425
pallium9.67e-1425
regional part of cerebral cortex2.32e-1222
pre-chordal neural plate4.39e-1261
ectoderm-derived structure1.00e-11171
ectoderm1.00e-11171
presumptive ectoderm1.00e-11171
neocortex3.19e-1120
structure with developmental contribution from neural crest7.58e-11132
ecto-epithelium1.79e-09104
organ system subdivision3.03e-08223
tissue9.16e-08773


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.