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Coexpression cluster:C761

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Full id: C761_myeloma_CD14_small_CD4_colon_duodenum_lymph



Phase1 CAGE Peaks

Hg19::chr16:79631335..79631361,-p@chr16:79631335..79631361
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Hg19::chr16:79631939..79631952,-p@chr16:79631939..79631952
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Hg19::chr16:79632143..79632166,-p@chr16:79632143..79632166
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Hg19::chr16:79632343..79632358,-p@chr16:79632343..79632358
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Hg19::chr16:79632381..79632430,-p@chr16:79632381..79632430
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Hg19::chr16:79632532..79632560,-p@chr16:79632532..79632560
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Hg19::chr16:79633883..79633892,-p6@MAF
Hg19::chr16:79633894..79633954,-p3@MAF
Hg19::chr16:79634581..79634592,-p4@MAF
Hg19::chr16:79634595..79634620,-p2@MAF
Hg19::chr16:79634624..79634642,-p1@MAF


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
adult organism5.44e-34114
neural tube1.95e-1356
neural rod1.95e-1356
future spinal cord1.95e-1356
neural keel1.95e-1356
neural plate1.81e-1282
presumptive neural plate1.81e-1282
regional part of nervous system3.76e-1253
regional part of brain3.76e-1253
neurectoderm2.17e-1186
central nervous system2.27e-1181
regional part of forebrain9.51e-1141
forebrain9.51e-1141
anterior neural tube9.51e-1141
future forebrain9.51e-1141
ecto-epithelium1.02e-10104
brain3.57e-1068
future brain3.57e-1068
brain grey matter4.12e-1034
gray matter4.12e-1034
telencephalon4.59e-1034
regional part of telencephalon1.42e-0932
pre-chordal neural plate2.57e-0961
cerebral hemisphere3.25e-0932
regional part of cerebral cortex9.69e-0922
nervous system2.21e-0889
organ4.51e-08503
organ system subdivision5.14e-08223
neocortex6.23e-0820
cerebral cortex6.66e-0825
pallium6.66e-0825
structure with developmental contribution from neural crest3.44e-07132
ectoderm-derived structure3.69e-07171
ectoderm3.69e-07171
presumptive ectoderm3.69e-07171


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.0370565
MA0004.10.349539
MA0006.10.605586
MA0007.10.332734
MA0009.10.79061
MA0014.10.36818
MA0017.10.24363
MA0019.10.486183
MA0024.10.688373
MA0025.10.921763
MA0027.12.39404
MA0028.10.224112
MA0029.10.707146
MA0030.10.696006
MA0031.10.633489
MA0038.10.443833
MA0040.10.712837
MA0041.11.70844
MA0042.10.337481
MA0043.10.790919
MA0046.10.779945
MA0048.10.185335
MA0050.10.338274
MA0051.10.439895
MA0052.10.716602
MA0055.10.279754
MA0056.10
MA0057.10.397382
MA0058.10.265212
MA0059.10.2641
MA0060.11.81683
MA0061.10.100525
MA0063.10
MA0066.10.444231
MA0067.11.1037
MA0068.12.54939
MA0069.10.776171
MA0070.10.765217
MA0071.10.40788
MA0072.10.760818
MA0073.162.1025
MA0074.10.439193
MA0076.10.278993
MA0077.10.753278
MA0078.10.533387
MA0081.10.26424
MA0083.10.79797
MA0084.11.28962
MA0087.10.758426
MA0088.10.0234479
MA0089.10
MA0090.10.291627
MA0091.10.351901
MA0092.10.852371
MA0093.10.213288
MA0095.10
MA0098.10
MA0100.10.456802
MA0101.10.216017
MA0103.10.203171
MA0105.10.0403209
MA0106.10.482519
MA0107.10.156959
MA0108.20.630531
MA0109.10
MA0111.10.303543
MA0113.10.498009
MA0114.10.153042
MA0115.11.02805
MA0116.10.159642
MA0117.10.827487
MA0119.10.250314
MA0122.10.852927
MA0124.10.98702
MA0125.10.904129
MA0130.10
MA0131.10.550695
MA0132.10
MA0133.10
MA0135.10.820382
MA0136.10.450422
MA0139.10.637178
MA0140.10.405425
MA0141.10.2626
MA0142.10.602852
MA0143.11.24556
MA0144.10.142196
MA0145.10.277793
MA0146.10.184736
MA0147.10.162359
MA0148.10.372124
MA0149.10.396509
MA0062.20.0969238
MA0035.20.404774
MA0039.21.21046
MA0138.20.534556
MA0002.20.111226
MA0137.20.229531
MA0104.20.118985
MA0047.20.47109
MA0112.20.0251803
MA0065.20.28513
MA0150.10.286461
MA0151.10
MA0152.11.05873
MA0153.10.887528
MA0154.10.0391503
MA0155.10.099499
MA0156.10.231442
MA0157.10.576556
MA0158.10
MA0159.11.51416
MA0160.10.386031
MA0161.10
MA0162.12.59489
MA0163.12.5883
MA0164.10.509774
MA0080.20.21336
MA0018.22.1073
MA0099.20.411824
MA0079.26.03814
MA0102.21.32663
MA0258.10.135061
MA0259.10.504687
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
CTBP2#1488317.10463645618040.0006070928651993480.0050682791165911



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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