MCL coexpression mm9:1286
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr11:4060221..4060234,- | p2@Ccdc157 |
| Mm9::chr11:4060235..4060285,- | p1@Ccdc157 |
| Mm9::chr11:4060289..4060308,- | p3@Ccdc157 |
| Mm9::chr12:88488099..88488151,+ | p2@Gstz1 |
| Mm9::chr14:58042931..58042948,+ | p2@Ift88 |
| Mm9::chr4:154460687..154460719,+ | p1@Morn1 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0016034 | maleylacetoacetate isomerase activity | 0.0101745724047251 |
| GO:0016853 | isomerase activity | 0.0101745724047251 |
| GO:0042487 | regulation of odontogenesis of dentine-containing teeth | 0.0162606022548207 |
| GO:0045862 | positive regulation of proteolysis | 0.0162606022548207 |
| GO:0006572 | tyrosine catabolic process | 0.0162606022548207 |
| GO:0006559 | L-phenylalanine catabolic process | 0.0162606022548207 |
| GO:0006558 | L-phenylalanine metabolic process | 0.0162606022548207 |
| GO:0005932 | basal body | 0.0162606022548207 |
| GO:0009074 | aromatic amino acid family catabolic process | 0.0162606022548207 |
| GO:0006570 | tyrosine metabolic process | 0.0162606022548207 |
| GO:0030162 | regulation of proteolysis | 0.0162606022548207 |
| GO:0019439 | aromatic compound catabolic process | 0.0162606022548207 |
| GO:0042733 | embryonic digit morphogenesis | 0.0162606022548207 |
| GO:0005930 | axoneme | 0.0249192623318852 |
| GO:0004364 | glutathione transferase activity | 0.0249192623318852 |
| GO:0009072 | aromatic amino acid family metabolic process | 0.0253904864530803 |
| GO:0007224 | smoothened signaling pathway | 0.0263858473302257 |
| GO:0007368 | determination of left/right symmetry | 0.0263858473302257 |
| GO:0016859 | cis-trans isomerase activity | 0.0263858473302257 |
| GO:0009855 | determination of bilateral symmetry | 0.0263858473302257 |
| GO:0009799 | determination of symmetry | 0.0263858473302257 |
| GO:0042475 | odontogenesis of dentine-containing teeth | 0.0263858473302257 |
| GO:0042476 | odontogenesis | 0.0263858473302257 |
| GO:0019861 | flagellum | 0.0263858473302257 |
| GO:0009953 | dorsal/ventral pattern formation | 0.027922280024024 |
| GO:0009063 | amino acid catabolic process | 0.0287167623369693 |
| GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups | 0.0301337658028662 |
| GO:0005815 | microtubule organizing center | 0.0301337658028662 |
| GO:0009310 | amine catabolic process | 0.0302816543141528 |
| GO:0044270 | nitrogen compound catabolic process | 0.0302816543141528 |
| GO:0030326 | embryonic limb morphogenesis | 0.0319254226005781 |
| GO:0035113 | embryonic appendage morphogenesis | 0.0319254226005781 |
| GO:0044463 | cell projection part | 0.0334058050564833 |
| GO:0051247 | positive regulation of protein metabolic process | 0.0336828146193963 |
| GO:0035107 | appendage morphogenesis | 0.0336828146193963 |
| GO:0035108 | limb morphogenesis | 0.0336828146193963 |
| GO:0048736 | appendage development | 0.0336828146193963 |
| GO:0060173 | limb development | 0.0336828146193963 |
| GO:0009952 | anterior/posterior pattern formation | 0.0390185070273834 |
| GO:0006725 | aromatic compound metabolic process | 0.0456849239475597 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| ecto-epithelium | 6.77e-11 | 73 |
| neurectoderm | 7.08e-11 | 64 |
| neural plate | 7.08e-11 | 64 |
| presumptive neural plate | 7.08e-11 | 64 |
| pre-chordal neural plate | 4.91e-10 | 49 |
| ectoderm-derived structure | 9.48e-10 | 95 |
| ectoderm | 9.48e-10 | 95 |
| presumptive ectoderm | 9.48e-10 | 95 |
| neural tube | 5.85e-09 | 52 |
| neural rod | 5.85e-09 | 52 |
| future spinal cord | 5.85e-09 | 52 |
| neural keel | 5.85e-09 | 52 |
| central nervous system | 7.08e-09 | 73 |
| regional part of nervous system | 1.30e-08 | 54 |
| brain | 3.61e-08 | 47 |
| future brain | 3.61e-08 | 47 |
| regional part of brain | 4.02e-08 | 46 |
| nervous system | 4.59e-08 | 75 |
| structure with developmental contribution from neural crest | 8.87e-08 | 92 |
| multi-cellular organism | 1.35e-07 | 333 |
| anterior neural tube | 3.08e-07 | 40 |
| regional part of forebrain | 4.94e-07 | 39 |
| forebrain | 4.94e-07 | 39 |
| future forebrain | 4.94e-07 | 39 |
| anatomical conduit | 6.60e-07 | 122 |
| tube | 8.99e-07 | 114 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.476238 |
| MA0004.1 | 0.536396 |
| MA0006.1 | 0.359699 |
| MA0007.1 | 1.29371 |
| MA0009.1 | 0.987341 |
| MA0014.1 | 0.12867 |
| MA0017.1 | 0.387481 |
| MA0019.1 | 0.800946 |
| MA0024.1 | 0.942716 |
| MA0025.1 | 1.22395 |
| MA0027.1 | 2.64231 |
| MA0028.1 | 3.55677 |
| MA0029.1 | 2.12396 |
| MA0030.1 | 0.927235 |
| MA0031.1 | 0.890871 |
| MA0038.1 | 0.686534 |
| MA0040.1 | 1.00009 |
| MA0041.1 | 0.457338 |
| MA0042.1 | 0.443591 |
| MA0043.1 | 1.08567 |
| MA0046.1 | 1.02391 |
| MA0048.1 | 0.161427 |
| MA0050.1 | 0.57678 |
| MA0051.1 | 0.695779 |
| MA0052.1 | 1.00829 |
| MA0055.1 | 0.465302 |
| MA0056.1 | 0 |
| MA0057.1 | 0.149949 |
| MA0058.1 | 0.436487 |
| MA0059.1 | 0.449345 |
| MA0060.1 | 0.757042 |
| MA0061.1 | 0.307097 |
| MA0063.1 | 0 |
| MA0066.1 | 0.675169 |
| MA0067.1 | 1.33603 |
| MA0068.1 | 0.467569 |
| MA0069.1 | 1.00864 |
| MA0070.1 | 0.998765 |
| MA0071.1 | 0.575909 |
| MA0072.1 | 0.990133 |
| MA0073.1 | 0.00140584 |
| MA0074.1 | 0.638014 |
| MA0076.1 | 4.86596 |
| MA0077.1 | 0.968053 |
| MA0078.1 | 0.729877 |
| MA0081.1 | 0.473489 |
| MA0083.1 | 1.08487 |
| MA0084.1 | 1.66561 |
| MA0087.1 | 1.04109 |
| MA0088.1 | 0.725434 |
| MA0089.1 | 0 |
| MA0090.1 | 0.500693 |
| MA0091.1 | 0.55008 |
| MA0092.1 | 1.25163 |
| MA0093.1 | 0.379257 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 1.51574 |
| MA0101.1 | 0.458688 |
| MA0103.1 | 0.398766 |
| MA0105.1 | 0.199622 |
| MA0106.1 | 0.737893 |
| MA0107.1 | 0.392331 |
| MA0108.2 | 0.824407 |
| MA0109.1 | 0 |
| MA0111.1 | 0.515457 |
| MA0113.1 | 0.708789 |
| MA0114.1 | 0.304661 |
| MA0115.1 | 1.08851 |
| MA0116.1 | 0.359483 |
| MA0117.1 | 1.05576 |
| MA0119.1 | 0.459301 |
| MA0122.1 | 1.07591 |
| MA0124.1 | 1.28237 |
| MA0125.1 | 1.20757 |
| MA0130.1 | 0 |
| MA0131.1 | 0.796279 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.1226 |
| MA0136.1 | 0.658622 |
| MA0139.1 | 0.243463 |
| MA0140.1 | 0.625902 |
| MA0141.1 | 0.419361 |
| MA0142.1 | 0.876028 |
| MA0143.1 | 0.725672 |
| MA0144.1 | 0.307873 |
| MA0145.1 | 0.119202 |
| MA0146.1 | 1.41218 |
| MA0147.1 | 0.858298 |
| MA0148.1 | 0.553294 |
| MA0149.1 | 0.464445 |
| MA0062.2 | 4.14052 |
| MA0035.2 | 0.630778 |
| MA0039.2 | 1.05907 |
| MA0138.2 | 0.788113 |
| MA0002.2 | 0.246463 |
| MA0137.2 | 0.416331 |
| MA0104.2 | 0.723439 |
| MA0047.2 | 0.685741 |
| MA0112.2 | 0.119197 |
| MA0065.2 | 0.119561 |
| MA0150.1 | 0.520653 |
| MA0151.1 | 0 |
| MA0152.1 | 0.685852 |
| MA0153.1 | 1.13945 |
| MA0154.1 | 0.159217 |
| MA0155.1 | 0.132921 |
| MA0156.1 | 1.84703 |
| MA0157.1 | 0.843181 |
| MA0158.1 | 0 |
| MA0159.1 | 0.331229 |
| MA0160.1 | 0.556423 |
| MA0161.1 | 0 |
| MA0162.1 | 0.176524 |
| MA0163.1 | 0.163321 |
| MA0164.1 | 0.658997 |
| MA0080.2 | 1.01893 |
| MA0018.2 | 1.60558 |
| MA0099.2 | 0.781628 |
| MA0079.2 | 0.147137 |
| MA0102.2 | 1.7182 |
| MA0258.1 | 0.290587 |
| MA0259.1 | 0.309517 |
| MA0442.1 | 0 |
