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MCL coexpression mm9:1385

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Phase1 CAGE Peaks

 Short description
Mm9::chr16:7149860..7149888,+p@chr16:7149860..7149888
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Mm9::chr16:7150004..7150009,+p@chr16:7150004..7150009
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Mm9::chr16:72027706..72027715,+p@chr16:72027706..72027715
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Mm9::chr6:15147087..15147102,+p@chr6:15147087..15147102
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Mm9::chr6:6813551..6813570,+p5@Dlx6
Mm9::chr6:6817869..6817879,+p@chr6:6817869..6817879
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0031223auditory behavior0.00624554867692982
GO:0042297vocal learning0.00624554867692982
GO:0007638mechanosensory behavior0.011369759253142
GO:0048745smooth muscle development0.011369759253142
GO:0043565sequence-specific DNA binding0.011369759253142
GO:0009790embryonic development0.011369759253142
GO:0010464regulation of mesenchymal cell proliferation0.0124883598790944
GO:0010463mesenchymal cell proliferation0.0124883598790944
GO:0002053positive regulation of mesenchymal cell proliferation0.0124883598790944
GO:0016566specific transcriptional repressor activity0.0136225454466081
GO:0048286alveolus development0.0136225454466081
GO:0050679positive regulation of epithelial cell proliferation0.0156078834662755
GO:0009612response to mechanical stimulus0.0157798799834461
GO:0003700transcription factor activity0.0157798799834461
GO:0022037metencephalon development0.0176233794549311
GO:0021549cerebellum development0.0176233794549311
GO:0050678regulation of epithelial cell proliferation0.0176233794549311
GO:0050673epithelial cell proliferation0.0214947659182327
GO:0030902hindbrain development0.027580886706257
GO:0007612learning0.0305629476379068
GO:0046982protein heterodimerization activity0.0320469327081517
GO:0030326embryonic limb morphogenesis0.0320469327081517
GO:0035113embryonic appendage morphogenesis0.0320469327081517
GO:0030324lung development0.0320469327081517
GO:0030323respiratory tube development0.0320469327081517
GO:0007611learning and/or memory0.0320469327081517
GO:0035107appendage morphogenesis0.0320469327081517
GO:0035108limb morphogenesis0.0320469327081517
GO:0048736appendage development0.0320469327081517
GO:0060173limb development0.0320469327081517
GO:0006355regulation of transcription, DNA-dependent0.0320469327081517
GO:0006351transcription, DNA-dependent0.0320469327081517
GO:0032774RNA biosynthetic process0.0320469327081517
GO:0003677DNA binding0.0320469327081517
GO:0007519skeletal muscle development0.0320469327081517
GO:0045449regulation of transcription0.0320469327081517
GO:0048856anatomical structure development0.0320469327081517
GO:0019219regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0320469327081517
GO:0042803protein homodimerization activity0.0320469327081517
GO:0006350transcription0.0320469327081517
GO:0010468regulation of gene expression0.0334005305199739
GO:0031323regulation of cellular metabolic process0.0352996593287968
GO:0014706striated muscle development0.0352996593287968
GO:0007275multicellular organismal development0.0352996593287968
GO:0019222regulation of metabolic process0.0354612481091163
GO:0016070RNA metabolic process0.0365458237090462
GO:0000122negative regulation of transcription from RNA polymerase II promoter0.0370658451526354
GO:0016564transcription repressor activity0.0396495844999568
GO:0007517muscle development0.0417780806289334
GO:0009628response to abiotic stimulus0.0417780806289334
GO:0042802identical protein binding0.041929498409596
GO:0008284positive regulation of cell proliferation0.042074881854482
GO:0007420brain development0.0427983996470997
GO:0045892negative regulation of transcription, DNA-dependent0.0427983996470997
GO:0010467gene expression0.0427983996470997
GO:0046983protein dimerization activity0.0427983996470997
GO:0048598embryonic morphogenesis0.0427983996470997
GO:0035295tube development0.0427983996470997
GO:0003676nucleic acid binding0.0427983996470997
GO:0032502developmental process0.0448239364889525
GO:0007417central nervous system development0.0468822209526583
GO:0006139nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0468822209526583
GO:0016481negative regulation of transcription0.0468822209526583
GO:0045934negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0494229147682189



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
CNS neuron (sensu Vertebrata)3.12e-1523
neuroblast (sensu Vertebrata)3.12e-1523
neuron2.45e-0833
neuronal stem cell2.45e-0833
neuroblast2.45e-0833
electrically signaling cell2.45e-0833

Uber Anatomy
Ontology termp-valuen
regional part of nervous system1.30e-1754
neural tube5.49e-1652
neural rod5.49e-1652
future spinal cord5.49e-1652
neural keel5.49e-1652
central nervous system1.64e-1473
neurectoderm2.24e-1464
neural plate2.24e-1464
presumptive neural plate2.24e-1464
gray matter8.10e-1434
nervous system1.02e-1375
brain2.88e-1347
future brain2.88e-1347
regional part of brain1.78e-1246
ectoderm-derived structure1.83e-1295
ectoderm1.83e-1295
presumptive ectoderm1.83e-1295
anterior neural tube2.47e-1240
ecto-epithelium3.31e-1273
pre-chordal neural plate4.45e-1249
regional part of forebrain1.61e-1139
forebrain1.61e-1139
future forebrain1.61e-1139
brain grey matter1.00e-1029
regional part of telencephalon1.00e-1029
telencephalon1.00e-1029
basal ganglion5.54e-088
nuclear complex of neuraxis5.54e-088
aggregate regional part of brain5.54e-088
collection of basal ganglia5.54e-088
cerebral subcortex5.54e-088
structure with developmental contribution from neural crest1.75e-0792


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.00973143
MA0004.10.536396
MA0006.10.359699
MA0007.10.52077
MA0009.10.987341
MA0014.10.0315641
MA0017.10.387481
MA0019.10.800946
MA0024.10.942716
MA0025.11.22395
MA0027.12.64231
MA0028.10.370592
MA0029.10.920529
MA0030.10.927235
MA0031.10.890871
MA0038.10.686534
MA0040.11.00009
MA0041.10.457338
MA0042.10.443591
MA0043.11.08567
MA0046.11.02391
MA0048.10.161427
MA0050.10.57678
MA0051.10.695779
MA0052.11.00829
MA0055.19.10523
MA0056.10
MA0057.10.149949
MA0058.10.436487
MA0059.10.449345
MA0060.12.1282
MA0061.10.307097
MA0063.10
MA0066.10.675169
MA0067.11.33603
MA0068.10.153907
MA0069.11.00864
MA0070.10.998765
MA0071.10.575909
MA0072.10.990133
MA0073.10.0960184
MA0074.10.638014
MA0076.10.407465
MA0077.10.968053
MA0078.10.729877
MA0081.10.473489
MA0083.11.08487
MA0084.11.66561
MA0087.11.04109
MA0088.10.111145
MA0089.10
MA0090.10.500693
MA0091.10.55008
MA0092.10.501022
MA0093.10.379257
MA0095.10
MA0098.10
MA0100.10.626021
MA0101.10.458688
MA0103.10.398766
MA0105.10.199622
MA0106.11.74856
MA0107.10.392331
MA0108.20.824407
MA0109.10
MA0111.10.515457
MA0113.10.708789
MA0114.10.304661
MA0115.11.08851
MA0116.10.359483
MA0117.11.05576
MA0119.10.459301
MA0122.11.07591
MA0124.11.28237
MA0125.12.707
MA0130.10
MA0131.10.796279
MA0132.10
MA0133.10
MA0135.11.1226
MA0136.10.658622
MA0139.10.243463
MA0140.10.625902
MA0141.10.419361
MA0142.10.876028
MA0143.10.725672
MA0144.10.307873
MA0145.10.119202
MA0146.10.0392287
MA0147.10.320675
MA0148.10.553294
MA0149.11.17328
MA0062.20.204999
MA0035.20.630778
MA0039.20.0271858
MA0138.20.788113
MA0002.20.246463
MA0137.20.416331
MA0104.20.261255
MA0047.20.685741
MA0112.20.119197
MA0065.20.380324
MA0150.10.520653
MA0151.10
MA0152.10.685852
MA0153.11.13945
MA0154.10.159217
MA0155.10.132921
MA0156.10.406559
MA0157.10.843181
MA0158.10
MA0159.10.331229
MA0160.10.556423
MA0161.10
MA0162.11.53386
MA0163.10.0423021
MA0164.10.658997
MA0080.20.393257
MA0018.20.669032
MA0099.20.781628
MA0079.20.0267793
MA0102.21.7182
MA0258.10.290587
MA0259.10.309517
MA0442.10
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