MCL coexpression mm9:1677
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr15:39491058..39491131,+ | p1@Rims2 |
| Mm9::chr15:72378118..72378137,- | p@chr15:72378118..72378137 - |
| Mm9::chr1:75543215..75543229,+ | p6@Slc4a3 |
| Mm9::chr4:122878468..122878513,+ | p4@Nt5c1a |
| Mm9::chr4:122878746..122878772,+ | p2@Nt5c1a |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0008253 | 5'-nucleotidase activity | 0.0242162498772717 |
| GO:0005452 | inorganic anion exchanger activity | 0.0242162498772717 |
| GO:0008252 | nucleotidase activity | 0.0242162498772717 |
| GO:0015380 | anion exchanger activity | 0.0242162498772717 |
| GO:0015106 | bicarbonate transmembrane transporter activity | 0.0242162498772717 |
| GO:0015301 | anion:anion antiporter activity | 0.0242162498772717 |
| GO:0015108 | chloride transmembrane transporter activity | 0.0242162498772717 |
| GO:0017137 | Rab GTPase binding | 0.0313776749010759 |
| GO:0017156 | calcium ion-dependent exocytosis | 0.0313776749010759 |
| GO:0030073 | insulin secretion | 0.0314828234138316 |
| GO:0030072 | peptide hormone secretion | 0.0314828234138316 |
| GO:0015103 | inorganic anion transmembrane transporter activity | 0.0314828234138316 |
| GO:0002790 | peptide secretion | 0.0314828234138316 |
| GO:0015297 | antiporter activity | 0.035735271435484 |
| GO:0015833 | peptide transport | 0.035735271435484 |
| GO:0046879 | hormone secretion | 0.0361407521892148 |
| GO:0006836 | neurotransmitter transport | 0.0378365687345399 |
| GO:0017016 | Ras GTPase binding | 0.0378365687345399 |
| GO:0031267 | small GTPase binding | 0.0378365687345399 |
| GO:0051020 | GTPase binding | 0.038755433051013 |
| GO:0019933 | cAMP-mediated signaling | 0.0402543445152911 |
| GO:0019935 | cyclic-nucleotide-mediated signaling | 0.040339193295129 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| structure with developmental contribution from neural crest | 3.71e-23 | 92 |
| central nervous system | 6.97e-19 | 73 |
| nervous system | 1.48e-18 | 75 |
| regional part of nervous system | 3.51e-18 | 54 |
| neurectoderm | 1.35e-16 | 64 |
| neural plate | 1.35e-16 | 64 |
| presumptive neural plate | 1.35e-16 | 64 |
| neural tube | 1.83e-16 | 52 |
| neural rod | 1.83e-16 | 52 |
| future spinal cord | 1.83e-16 | 52 |
| neural keel | 1.83e-16 | 52 |
| ectoderm-derived structure | 5.68e-15 | 95 |
| ectoderm | 5.68e-15 | 95 |
| presumptive ectoderm | 5.68e-15 | 95 |
| brain | 6.05e-15 | 47 |
| future brain | 6.05e-15 | 47 |
| regional part of brain | 4.13e-14 | 46 |
| ecto-epithelium | 1.60e-12 | 73 |
| anterior neural tube | 3.19e-12 | 40 |
| pre-chordal neural plate | 5.25e-12 | 49 |
| regional part of forebrain | 1.60e-11 | 39 |
| forebrain | 1.60e-11 | 39 |
| future forebrain | 1.60e-11 | 39 |
| gray matter | 7.75e-10 | 34 |
| occipital lobe | 8.24e-10 | 10 |
| visual cortex | 8.24e-10 | 10 |
| neocortex | 8.24e-10 | 10 |
| brain grey matter | 2.19e-08 | 29 |
| regional part of telencephalon | 2.19e-08 | 29 |
| telencephalon | 2.19e-08 | 29 |
| regional part of cerebral cortex | 1.97e-07 | 17 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.989123 |
| MA0004.1 | 0.603793 |
| MA0006.1 | 1.07705 |
| MA0007.1 | 0.587678 |
| MA0009.1 | 1.06266 |
| MA0014.1 | 2.11217 |
| MA0017.1 | 0.449113 |
| MA0019.1 | 0.874061 |
| MA0024.1 | 1.01759 |
| MA0025.1 | 1.30092 |
| MA0027.1 | 2.72141 |
| MA0028.1 | 0.43138 |
| MA0029.1 | 0.995171 |
| MA0030.1 | 1.00195 |
| MA0031.1 | 0.965177 |
| MA0038.1 | 0.757669 |
| MA0040.1 | 1.07552 |
| MA0041.1 | 0.522007 |
| MA0042.1 | 0.507715 |
| MA0043.1 | 1.1618 |
| MA0046.1 | 1.09955 |
| MA0048.1 | 0.205696 |
| MA0050.1 | 0.645342 |
| MA0051.1 | 0.767098 |
| MA0052.1 | 1.08379 |
| MA0055.1 | 2.6907 |
| MA0056.1 | 0 |
| MA0057.1 | 1.68574 |
| MA0058.1 | 0.50032 |
| MA0059.1 | 0.513699 |
| MA0060.1 | 0.330907 |
| MA0061.1 | 0.364227 |
| MA0063.1 | 0 |
| MA0066.1 | 0.746072 |
| MA0067.1 | 1.41352 |
| MA0068.1 | 0.197245 |
| MA0069.1 | 1.08414 |
| MA0070.1 | 1.07418 |
| MA0071.1 | 0.644448 |
| MA0072.1 | 1.06547 |
| MA0073.1 | 0.310158 |
| MA0074.1 | 0.708108 |
| MA0076.1 | 0.470037 |
| MA0077.1 | 1.04318 |
| MA0078.1 | 0.801834 |
| MA0081.1 | 0.53877 |
| MA0083.1 | 1.16099 |
| MA0084.1 | 1.74401 |
| MA0087.1 | 1.11687 |
| MA0088.1 | 0.888325 |
| MA0089.1 | 0 |
| MA0090.1 | 2.38058 |
| MA0091.1 | 1.4987 |
| MA0092.1 | 0.567278 |
| MA0093.1 | 0.440484 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.695835 |
| MA0101.1 | 0.523409 |
| MA0103.1 | 0.460936 |
| MA0105.1 | 0.248108 |
| MA0106.1 | 0.809991 |
| MA0107.1 | 0.454197 |
| MA0108.2 | 0.897859 |
| MA0109.1 | 0 |
| MA0111.1 | 0.582193 |
| MA0113.1 | 0.780358 |
| MA0114.1 | 0.361633 |
| MA0115.1 | 1.16466 |
| MA0116.1 | 0.419688 |
| MA0117.1 | 1.13165 |
| MA0119.1 | 0.524046 |
| MA0122.1 | 1.15196 |
| MA0124.1 | 1.35963 |
| MA0125.1 | 1.28445 |
| MA0130.1 | 0 |
| MA0131.1 | 0.869325 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.19898 |
| MA0136.1 | 0.729175 |
| MA0139.1 | 0.8026 |
| MA0140.1 | 0.695713 |
| MA0141.1 | 1.21195 |
| MA0142.1 | 0.950155 |
| MA0143.1 | 0.797553 |
| MA0144.1 | 0.365053 |
| MA0145.1 | 0.157686 |
| MA0146.1 | 0.822925 |
| MA0147.1 | 0.378658 |
| MA0148.1 | 0.621195 |
| MA0149.1 | 0.529387 |
| MA0062.2 | 0.254018 |
| MA0035.2 | 0.700704 |
| MA0039.2 | 0.489701 |
| MA0138.2 | 0.861035 |
| MA0002.2 | 0.299191 |
| MA0137.2 | 0.479301 |
| MA0104.2 | 0.315156 |
| MA0047.2 | 0.75686 |
| MA0112.2 | 0.927461 |
| MA0065.2 | 0.158101 |
| MA0150.1 | 0.587557 |
| MA0151.1 | 0 |
| MA0152.1 | 0.756973 |
| MA0153.1 | 1.21594 |
| MA0154.1 | 0.203217 |
| MA0155.1 | 0.515751 |
| MA0156.1 | 0.469089 |
| MA0157.1 | 0.91689 |
| MA0158.1 | 0 |
| MA0159.1 | 0.389847 |
| MA0160.1 | 0.624415 |
| MA0161.1 | 0 |
| MA0162.1 | 0.526186 |
| MA0163.1 | 0.855539 |
| MA0164.1 | 0.729558 |
| MA0080.2 | 0.455167 |
| MA0018.2 | 0.739807 |
| MA0099.2 | 0.854449 |
| MA0079.2 | 2.6586 |
| MA0102.2 | 1.79669 |
| MA0258.1 | 0.346619 |
| MA0259.1 | 0.366802 |
| MA0442.1 | 0 |
