MCL coexpression mm9:1920
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr10:80204967..80205025,- | p1@Ap3d1 |
| Mm9::chr17:34742800..34742807,+ | p5@Agpat1 |
| Mm9::chr2:152119567..152119597,+ | p2@Tbc1d20 |
| Mm9::chr7:149088266..149088353,- | p1@Tollip |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0048003 | antigen processing and presentation of lipid antigen via MHC class Ib | 0.0176731013834793 |
| GO:0048007 | antigen processing and presentation, exogenous lipid antigen via MHC class Ib | 0.0176731013834793 |
| GO:0002475 | antigen processing and presentation via MHC class Ib | 0.0176731013834793 |
| GO:0051136 | regulation of NK T cell differentiation | 0.0176731013834793 |
| GO:0001865 | NK T cell differentiation | 0.0176731013834793 |
| GO:0051138 | positive regulation of NK T cell differentiation | 0.0176731013834793 |
| GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity | 0.0340698345234604 |
| GO:0016411 | acylglycerol O-acyltransferase activity | 0.0430463304984218 |
| GO:0046632 | alpha-beta T cell differentiation | 0.0484853132184813 |
| GO:0019884 | antigen processing and presentation of exogenous antigen | 0.0484853132184813 |
| GO:0032313 | regulation of Rab GTPase activity | 0.0484853132184813 |
| GO:0032483 | regulation of Rab protein signal transduction | 0.0484853132184813 |
| GO:0032482 | Rab protein signal transduction | 0.0484853132184813 |
| GO:0008374 | O-acyltransferase activity | 0.0484853132184813 |
| GO:0046631 | alpha-beta T cell activation | 0.0484853132184813 |
| GO:0005097 | Rab GTPase activator activity | 0.0484853132184813 |
| GO:0005802 | trans-Golgi network | 0.0484853132184813 |
| GO:0032318 | regulation of Ras GTPase activity | 0.0484853132184813 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| non-terminally differentiated cell | 1.32e-07 | 49 |
| Ontology term | p-value | n |
|---|---|---|
| regional part of nervous system | 9.27e-18 | 54 |
| central nervous system | 7.25e-17 | 73 |
| nervous system | 9.69e-17 | 75 |
| neural tube | 1.17e-16 | 52 |
| neural rod | 1.17e-16 | 52 |
| future spinal cord | 1.17e-16 | 52 |
| neural keel | 1.17e-16 | 52 |
| brain | 5.84e-15 | 47 |
| future brain | 5.84e-15 | 47 |
| regional part of brain | 1.45e-14 | 46 |
| ectoderm-derived structure | 3.38e-14 | 95 |
| ectoderm | 3.38e-14 | 95 |
| presumptive ectoderm | 3.38e-14 | 95 |
| gray matter | 2.71e-13 | 34 |
| anterior neural tube | 3.05e-12 | 40 |
| adult organism | 4.39e-12 | 51 |
| brain grey matter | 6.83e-12 | 29 |
| regional part of telencephalon | 6.83e-12 | 29 |
| telencephalon | 6.83e-12 | 29 |
| regional part of forebrain | 1.12e-11 | 39 |
| forebrain | 1.12e-11 | 39 |
| future forebrain | 1.12e-11 | 39 |
| neurectoderm | 1.50e-11 | 64 |
| neural plate | 1.50e-11 | 64 |
| presumptive neural plate | 1.50e-11 | 64 |
| ecto-epithelium | 1.28e-10 | 73 |
| cerebral cortex | 8.35e-10 | 21 |
| cerebral hemisphere | 8.35e-10 | 21 |
| pallium | 8.35e-10 | 21 |
| regional part of cerebral cortex | 5.10e-09 | 17 |
| pre-chordal neural plate | 1.89e-08 | 49 |
| occipital lobe | 1.07e-07 | 10 |
| visual cortex | 1.07e-07 | 10 |
| neocortex | 1.07e-07 | 10 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.942378 |
| MA0004.1 | 0.6888 |
| MA0006.1 | 1.24418 |
| MA0007.1 | 0.672186 |
| MA0009.1 | 1.15569 |
| MA0014.1 | 1.46333 |
| MA0017.1 | 0.528196 |
| MA0019.1 | 0.964875 |
| MA0024.1 | 1.11019 |
| MA0025.1 | 1.39562 |
| MA0027.1 | 2.81824 |
| MA0028.1 | 1.26991 |
| MA0029.1 | 1.08753 |
| MA0030.1 | 1.09438 |
| MA0031.1 | 1.05719 |
| MA0038.1 | 0.846479 |
| MA0040.1 | 1.16866 |
| MA0041.1 | 0.604221 |
| MA0042.1 | 0.589368 |
| MA0043.1 | 1.25564 |
| MA0046.1 | 1.1929 |
| MA0048.1 | 0.735223 |
| MA0050.1 | 0.731539 |
| MA0051.1 | 0.856094 |
| MA0052.1 | 1.17701 |
| MA0055.1 | 0.396346 |
| MA0056.1 | 0 |
| MA0057.1 | 0.251896 |
| MA0058.1 | 1.4226 |
| MA0059.1 | 0.59559 |
| MA0060.1 | 1.04037 |
| MA0061.1 | 0.438628 |
| MA0063.1 | 0 |
| MA0066.1 | 0.834648 |
| MA0067.1 | 1.50873 |
| MA0068.1 | 0.713436 |
| MA0069.1 | 1.17737 |
| MA0070.1 | 1.16732 |
| MA0071.1 | 0.73062 |
| MA0072.1 | 1.15853 |
| MA0073.1 | 0.552621 |
| MA0074.1 | 1.86824 |
| MA0076.1 | 1.35592 |
| MA0077.1 | 1.13603 |
| MA0078.1 | 0.891476 |
| MA0081.1 | 1.5065 |
| MA0083.1 | 1.25482 |
| MA0084.1 | 1.84013 |
| MA0087.1 | 1.21037 |
| MA0088.1 | 0.201215 |
| MA0089.1 | 0 |
| MA0090.1 | 0.650768 |
| MA0091.1 | 0.703314 |
| MA0092.1 | 0.651119 |
| MA0093.1 | 1.29026 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.783305 |
| MA0101.1 | 0.605676 |
| MA0103.1 | 0.540576 |
| MA0105.1 | 0.313353 |
| MA0106.1 | 0.899777 |
| MA0107.1 | 0.533522 |
| MA0108.2 | 0.989014 |
| MA0109.1 | 0 |
| MA0111.1 | 0.666525 |
| MA0113.1 | 0.869608 |
| MA0114.1 | 0.43587 |
| MA0115.1 | 1.25852 |
| MA0116.1 | 0.497293 |
| MA0117.1 | 2.74278 |
| MA0119.1 | 0.606338 |
| MA0122.1 | 1.24573 |
| MA0124.1 | 1.45461 |
| MA0125.1 | 1.37907 |
| MA0130.1 | 0 |
| MA0131.1 | 0.960068 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.29308 |
| MA0136.1 | 0.817395 |
| MA0139.1 | 0.365453 |
| MA0140.1 | 0.78318 |
| MA0141.1 | 0.563066 |
| MA0142.1 | 1.04199 |
| MA0143.1 | 0.887119 |
| MA0144.1 | 0.439506 |
| MA0145.1 | 0.608454 |
| MA0146.1 | 0.647546 |
| MA0147.1 | 0.453952 |
| MA0148.1 | 0.706718 |
| MA0149.1 | 0.611881 |
| MA0062.2 | 2.34802 |
| MA0035.2 | 0.788288 |
| MA0039.2 | 4.7835 |
| MA0138.2 | 0.951653 |
| MA0002.2 | 0.368961 |
| MA0137.2 | 0.559766 |
| MA0104.2 | 0.386166 |
| MA0047.2 | 0.845655 |
| MA0112.2 | 0.211985 |
| MA0065.2 | 0.212467 |
| MA0150.1 | 0.67206 |
| MA0151.1 | 0 |
| MA0152.1 | 0.84577 |
| MA0153.1 | 1.31015 |
| MA0154.1 | 1.34071 |
| MA0155.1 | 0.230016 |
| MA0156.1 | 1.35382 |
| MA0157.1 | 1.0083 |
| MA0158.1 | 0 |
| MA0159.1 | 1.1762 |
| MA0160.1 | 0.71003 |
| MA0161.1 | 0 |
| MA0162.1 | 1.16288 |
| MA0163.1 | 0.0996272 |
| MA0164.1 | 0.817786 |
| MA0080.2 | 1.32296 |
| MA0018.2 | 0.828253 |
| MA0099.2 | 0.944966 |
| MA0079.2 | 1.90618 |
| MA0102.2 | 1.8929 |
| MA0258.1 | 0.419871 |
| MA0259.1 | 0.441366 |
| MA0442.1 | 0 |
