MCL coexpression mm9:3384
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr3:108248065..108248096,- | p1@Sars |
| Mm9::chr3:108248101..108248129,- | p2@Sars |
| Mm9::chr4:128867107..128867200,+ | p1@Yars |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0043038 | amino acid activation | 5.53017928454632e-05 |
| GO:0043039 | tRNA aminoacylation | 5.53017928454632e-05 |
| GO:0006418 | tRNA aminoacylation for protein translation | 5.53017928454632e-05 |
| GO:0016876 | ligase activity, forming aminoacyl-tRNA and related compounds | 5.53017928454632e-05 |
| GO:0016875 | ligase activity, forming carbon-oxygen bonds | 5.53017928454632e-05 |
| GO:0004812 | aminoacyl-tRNA ligase activity | 5.53017928454632e-05 |
| GO:0006399 | tRNA metabolic process | 0.000199521774478894 |
| GO:0006520 | amino acid metabolic process | 0.000803815791288871 |
| GO:0006434 | seryl-tRNA aminoacylation | 0.000858282884454908 |
| GO:0004828 | serine-tRNA ligase activity | 0.000858282884454908 |
| GO:0004831 | tyrosine-tRNA ligase activity | 0.000858282884454908 |
| GO:0006437 | tyrosyl-tRNA aminoacylation | 0.000858282884454908 |
| GO:0006519 | amino acid and derivative metabolic process | 0.00085993419714682 |
| GO:0016874 | ligase activity | 0.00100874984582194 |
| GO:0009308 | amine metabolic process | 0.00100874984582194 |
| GO:0006807 | nitrogen compound metabolic process | 0.00109559623274966 |
| GO:0006412 | translation | 0.00148691136252163 |
| GO:0019752 | carboxylic acid metabolic process | 0.00148691136252163 |
| GO:0006082 | organic acid metabolic process | 0.00148691136252163 |
| GO:0009059 | macromolecule biosynthetic process | 0.00288472209210212 |
| GO:0000049 | tRNA binding | 0.00294187802669021 |
| GO:0044249 | cellular biosynthetic process | 0.0045300786801657 |
| GO:0009058 | biosynthetic process | 0.00793648198463862 |
| GO:0005524 | ATP binding | 0.00876794125052577 |
| GO:0032559 | adenyl ribonucleotide binding | 0.00876794125052577 |
| GO:0030554 | adenyl nucleotide binding | 0.00929024541403085 |
| GO:0032553 | ribonucleotide binding | 0.0121595522398973 |
| GO:0032555 | purine ribonucleotide binding | 0.0121595522398973 |
| GO:0017076 | purine nucleotide binding | 0.0126960618437547 |
| GO:0000166 | nucleotide binding | 0.0157397084846313 |
| GO:0016070 | RNA metabolic process | 0.0223576884150985 |
| GO:0044267 | cellular protein metabolic process | 0.029193421430314 |
| GO:0044260 | cellular macromolecule metabolic process | 0.029193421430314 |
| GO:0010467 | gene expression | 0.029193421430314 |
| GO:0019538 | protein metabolic process | 0.02967869063179 |
| GO:0006139 | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 0.0335849292761187 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| non-terminally differentiated cell | 1.24e-12 | 49 |
| ectodermal cell | 1.20e-11 | 44 |
| neurectodermal cell | 1.20e-11 | 44 |
| neural cell | 1.21e-11 | 43 |
| electrically responsive cell | 1.20e-10 | 39 |
| electrically active cell | 1.20e-10 | 39 |
| CNS neuron (sensu Vertebrata) | 1.62e-10 | 23 |
| neuroblast (sensu Vertebrata) | 1.62e-10 | 23 |
| neuron | 9.86e-10 | 33 |
| neuronal stem cell | 9.86e-10 | 33 |
| neuroblast | 9.86e-10 | 33 |
| electrically signaling cell | 9.86e-10 | 33 |
| Ontology term | p-value | n |
|---|---|---|
| ectoderm-derived structure | 1.89e-23 | 95 |
| ectoderm | 1.89e-23 | 95 |
| presumptive ectoderm | 1.89e-23 | 95 |
| nervous system | 1.52e-22 | 75 |
| central nervous system | 1.28e-21 | 73 |
| regional part of nervous system | 6.46e-19 | 54 |
| ecto-epithelium | 3.22e-18 | 73 |
| neural tube | 5.06e-18 | 52 |
| neural rod | 5.06e-18 | 52 |
| future spinal cord | 5.06e-18 | 52 |
| neural keel | 5.06e-18 | 52 |
| neurectoderm | 7.94e-18 | 64 |
| neural plate | 7.94e-18 | 64 |
| presumptive neural plate | 7.94e-18 | 64 |
| gray matter | 4.93e-16 | 34 |
| brain | 6.71e-16 | 47 |
| future brain | 6.71e-16 | 47 |
| regional part of brain | 1.47e-15 | 46 |
| brain grey matter | 2.56e-14 | 29 |
| regional part of telencephalon | 2.56e-14 | 29 |
| telencephalon | 2.56e-14 | 29 |
| anterior neural tube | 1.69e-13 | 40 |
| pre-chordal neural plate | 2.97e-13 | 49 |
| regional part of forebrain | 5.94e-13 | 39 |
| forebrain | 5.94e-13 | 39 |
| future forebrain | 5.94e-13 | 39 |
| structure with developmental contribution from neural crest | 2.18e-11 | 92 |
| cerebral cortex | 6.13e-11 | 21 |
| cerebral hemisphere | 6.13e-11 | 21 |
| pallium | 6.13e-11 | 21 |
| regional part of cerebral cortex | 1.40e-09 | 17 |
| occipital lobe | 5.64e-07 | 10 |
| visual cortex | 5.64e-07 | 10 |
| neocortex | 5.64e-07 | 10 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
| MA0003.1 | 0.245953 |
| MA0004.1 | 0.801718 |
| MA0006.1 | 0.60285 |
| MA0007.1 | 0.784593 |
| MA0009.1 | 1.27673 |
| MA0014.1 | 0.133574 |
| MA0017.1 | 0.635031 |
| MA0019.1 | 1.08369 |
| MA0024.1 | 1.23079 |
| MA0025.1 | 1.51835 |
| MA0027.1 | 2.9431 |
| MA0028.1 | 1.49373 |
| MA0029.1 | 1.20789 |
| MA0030.1 | 1.21482 |
| MA0031.1 | 1.17722 |
| MA0038.1 | 0.963265 |
| MA0040.1 | 1.28983 |
| MA0041.1 | 0.714279 |
| MA0042.1 | 0.69885 |
| MA0043.1 | 1.3775 |
| MA0046.1 | 1.31428 |
| MA0048.1 | 0.353763 |
| MA0050.1 | 0.845669 |
| MA0051.1 | 0.973068 |
| MA0052.1 | 1.29825 |
| MA0055.1 | 0.190475 |
| MA0056.1 | 0 |
| MA0057.1 | 0.337566 |
| MA0058.1 | 0.690848 |
| MA0059.1 | 0.705317 |
| MA0060.1 | 0.502699 |
| MA0061.1 | 0.5406 |
| MA0063.1 | 0 |
| MA0066.1 | 0.951196 |
| MA0067.1 | 1.63197 |
| MA0068.1 | 0.343188 |
| MA0069.1 | 1.29861 |
| MA0070.1 | 1.28847 |
| MA0071.1 | 0.844726 |
| MA0072.1 | 1.2796 |
| MA0073.1 | 0.0430758 |
| MA0074.1 | 0.911576 |
| MA0076.1 | 1.58243 |
| MA0077.1 | 1.2569 |
| MA0078.1 | 1.0091 |
| MA0081.1 | 0.732313 |
| MA0083.1 | 1.37668 |
| MA0084.1 | 1.96428 |
| MA0087.1 | 1.33189 |
| MA0088.1 | 0.27999 |
| MA0089.1 | 0 |
| MA0090.1 | 0.762482 |
| MA0091.1 | 0.816659 |
| MA0092.1 | 0.762845 |
| MA0093.1 | 0.62555 |
| MA0095.1 | 0 |
| MA0098.1 | 0 |
| MA0100.1 | 0.89873 |
| MA0101.1 | 0.71579 |
| MA0103.1 | 0.647985 |
| MA0105.1 | 0.405648 |
| MA0106.1 | 1.01755 |
| MA0107.1 | 0.640607 |
| MA0108.2 | 1.10817 |
| MA0109.1 | 0 |
| MA0111.1 | 0.778753 |
| MA0113.1 | 0.986839 |
| MA0114.1 | 0.537669 |
| MA0115.1 | 1.38041 |
| MA0116.1 | 0.602598 |
| MA0117.1 | 1.34691 |
| MA0119.1 | 0.716476 |
| MA0122.1 | 1.36752 |
| MA0124.1 | 1.57762 |
| MA0125.1 | 1.5017 |
| MA0130.1 | 0 |
| MA0131.1 | 1.07881 |
| MA0132.1 | 0 |
| MA0133.1 | 0 |
| MA0135.1 | 1.4152 |
| MA0136.1 | 0.933582 |
| MA0139.1 | 2.03543 |
| MA0140.1 | 0.898603 |
| MA0141.1 | 0.671467 |
| MA0142.1 | 1.16183 |
| MA0143.1 | 1.00467 |
| MA0144.1 | 0.541532 |
| MA0145.1 | 0.292366 |
| MA0146.1 | 0.46063 |
| MA0147.1 | 0.556853 |
| MA0148.1 | 0.820161 |
| MA0149.1 | 0.722227 |
| MA0062.2 | 1.86813 |
| MA0035.2 | 0.903829 |
| MA0039.2 | 2.07301 |
| MA0138.2 | 1.07027 |
| MA0002.2 | 0.466067 |
| MA0137.2 | 0.668025 |
| MA0104.2 | 0.48458 |
| MA0047.2 | 0.962424 |
| MA0112.2 | 0.794478 |
| MA0065.2 | 0.292912 |
| MA0150.1 | 0.784464 |
| MA0151.1 | 0 |
| MA0152.1 | 0.962542 |
| MA0153.1 | 1.43238 |
| MA0154.1 | 0.35067 |
| MA0155.1 | 0.312898 |
| MA0156.1 | 0.656895 |
| MA0157.1 | 1.12772 |
| MA0158.1 | 0 |
| MA0159.1 | 0.569393 |
| MA0160.1 | 0.823568 |
| MA0161.1 | 0 |
| MA0162.1 | 0.166722 |
| MA0163.1 | 0.157796 |
| MA0164.1 | 0.933981 |
| MA0080.2 | 0.64167 |
| MA0018.2 | 0.944669 |
| MA0099.2 | 1.06348 |
| MA0079.2 | 0.890297 |
| MA0102.2 | 2.01714 |
| MA0258.1 | 0.520639 |
| MA0259.1 | 0.543506 |
| MA0442.1 | 0 |
