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|full_id=C2781_heart_Endothelial_mesenchymal_Myoblast_Preadipocyte_Cardiac_Synoviocyte
|full_id=C2781_heart_Endothelial_mesenchymal_Myoblast_Preadipocyte_Cardiac_Synoviocyte
|id=C2781
|id=C2781
|ontology_enrichment_celltype=CL:0002139!5.40e-13!24;CL:0000115!4.26e-12!35;CL:0000071!6.78e-10!18;CL:0002546!6.78e-10!18;CL:0000222!9.61e-10!119;CL:0002078!3.37e-09!44;CL:0000136!6.34e-09!15;CL:0002334!2.24e-08!12;CL:0000680!4.75e-07!57;CL:0000056!4.75e-07!57;CL:0000355!4.75e-07!57;CL:0002057!9.03e-07!42
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0000468!3.72e-20!659;UBERON:0004872!6.24e-19!84;UBERON:0007023!1.71e-16!115;UBERON:0000467!3.31e-16!625;UBERON:0000480!5.96e-16!626;UBERON:0001009!6.39e-16!113;UBERON:0003081!7.96e-16!216;UBERON:0000926!1.59e-15!448;UBERON:0004120!1.59e-15!448;UBERON:0006603!1.59e-15!448;UBERON:0004535!1.14e-14!110;UBERON:0000055!1.47e-13!69;UBERON:0001981!3.01e-12!60;UBERON:0007500!3.01e-12!60;UBERON:0004537!3.01e-12!60;UBERON:0006965!3.01e-12!60;UBERON:0000479!3.88e-12!787;UBERON:0002049!6.43e-12!79;UBERON:0007798!6.43e-12!79;UBERON:0000922!6.94e-12!612;UBERON:0002050!1.19e-11!605;UBERON:0005423!1.19e-11!605;UBERON:0007100!1.87e-11!27;UBERON:0003914!2.32e-11!118;UBERON:0000923!2.54e-11!604;UBERON:0005291!2.54e-11!604;UBERON:0006598!2.54e-11!604;UBERON:0002532!2.54e-11!604;UBERON:0004111!1.25e-10!241;UBERON:0000948!6.12e-10!24;UBERON:0005498!6.12e-10!24;UBERON:0004140!6.12e-10!24;UBERON:0009881!6.12e-10!24;UBERON:0004141!6.12e-10!24;UBERON:0003084!6.12e-10!24;UBERON:0007005!6.12e-10!24;UBERON:0004139!6.12e-10!24;UBERON:0004291!6.12e-10!24;UBERON:0001986!6.78e-10!18;UBERON:0004638!6.78e-10!18;UBERON:0004852!6.78e-10!18;UBERON:0000025!1.12e-09!194;UBERON:0002204!1.38e-08!167;UBERON:0002385!1.80e-08!63;UBERON:0001015!1.80e-08!63;UBERON:0000383!1.80e-08!63;UBERON:0000490!2.75e-08!138;UBERON:0001134!5.50e-08!61;UBERON:0002036!5.50e-08!61;UBERON:0003082!5.50e-08!61;UBERON:0000477!6.71e-08!286;UBERON:0006914!8.44e-08!25;UBERON:0000487!1.55e-07!22;UBERON:0001637!7.38e-07!42;UBERON:0003509!7.38e-07!42;UBERON:0004572!7.38e-07!42
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Revision as of 14:28, 21 May 2012


Full id: C2781_heart_Endothelial_mesenchymal_Myoblast_Preadipocyte_Cardiac_Synoviocyte



Phase1 CAGE Peaks

Hg19::chr4:159092525..159092574,-p4@FAM198B
Hg19::chr4:159092576..159092617,-p8@FAM198B
Hg19::chr4:159092626..159092672,-p6@FAM198B
Hg19::chr4:159092677..159092708,-p9@FAM198B


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
multi-cellular organism3.72e-20659
splanchnic layer of lateral plate mesoderm6.24e-1984
adult organism1.71e-16115
anatomical system3.31e-16625
anatomical group5.96e-16626
circulatory system6.39e-16113
lateral plate mesoderm7.96e-16216
mesoderm1.59e-15448
mesoderm-derived structure1.59e-15448
presumptive mesoderm1.59e-15448
cardiovascular system1.14e-14110
vessel1.47e-1369
blood vessel3.01e-1260
epithelial tube open at both ends3.01e-1260
blood vasculature3.01e-1260
vascular cord3.01e-1260
tissue3.88e-12787
vasculature6.43e-1279
vascular system6.43e-1279
embryo6.94e-12612
embryonic structure1.19e-11605
developing anatomical structure1.19e-11605
primary circulatory organ1.87e-1127
epithelial tube2.32e-11118
germ layer2.54e-11604
embryonic tissue2.54e-11604
presumptive structure2.54e-11604
epiblast (generic)2.54e-11604
anatomical conduit1.25e-10241
heart6.12e-1024
primitive heart tube6.12e-1024
primary heart field6.12e-1024
anterior lateral plate mesoderm6.12e-1024
heart tube6.12e-1024
heart primordium6.12e-1024
cardiac mesoderm6.12e-1024
cardiogenic plate6.12e-1024
heart rudiment6.12e-1024
endothelium6.78e-1018
blood vessel endothelium6.78e-1018
cardiovascular system endothelium6.78e-1018
tube1.12e-09194
musculoskeletal system1.38e-08167
muscle tissue1.80e-0863
musculature1.80e-0863
musculature of body1.80e-0863
unilaminar epithelium2.75e-08138
skeletal muscle tissue5.50e-0861
striated muscle tissue5.50e-0861
myotome5.50e-0861
anatomical cluster6.71e-08286
squamous epithelium8.44e-0825
simple squamous epithelium1.55e-0722
artery7.38e-0742
arterial blood vessel7.38e-0742
arterial system7.38e-0742


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.