FF:11871-125B8: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005047 | ||
| | |accession_numbers=CAGE;DRX008151;DRR009023;DRZ000448;DRZ001833;DRZ011798;DRZ013183 | ||
| | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000766,CL:0000219,CL:0000325,CL:0000473,CL:0000234,CL:0000738,CL:0002087,CL:0000255,CL:0000576,CL:0000860,CL:0002057 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001,FF:0000350,FF:0000629,FF:0011443 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr2:68592406..68592424,+!p1@PLEK!3.31!2019.77!PLEK;;chr16:85932760..85932775,+!p1@IRF8!3.00!1004.10!IRF8;;chr11:47400078..47400106,-!p1@SPI1!2.71!512.62!SPI1;;chr12:54778471..54778528,-!p1@ZNF385A!2.61!405.51!ZNF385A;;chr7:115670804..115670825,-!p1@TFEC!2.30!199.86!TFEC;;chr6:36355431..36355466,-!p1@ETV7!2.17!147.40!ETV7;;chr10:35484053..35484076,+!p1@CREM!2.16!343.28!CREM;;chr11:47399947..47399961,-!p3@SPI1!2.14!135.64!SPI1;;chr1:25256756..25256774,-!p1@RUNX3!2.10!230.18!RUNX3;;chr7:128577972..128578047,+!p1@IRF5!2.09!186.90!IRF5;;chr21:34442439..34442455,+!p1@OLIG1!2.06!114.29!OLIG1;;chr10:64576105..64576133,-!p1@EGR2!2.05!223.20!EGR2;;chr6:106534192..106534224,+!p1@PRDM1!2.00!265.69!PRDM1;;chr11:47400062..47400077,-!p2@SPI1!1.97!91.75!SPI1;;chr2:70142232..70142251,+!p1@MXD1!1.96!483.90!MXD1;;chr11:64764435..64764449,-!p1@BATF2!1.96!121.67!BATF2;;chr11:47399996..47400014,-!p4@SPI1!1.92!82.18!SPI1;;chr5:131826457..131826514,-!p1@IRF1!1.90!2870.08!IRF1;;chr20:39317868..39317884,-!p1@MAFB!1.89!844.73!MAFB;;chr11:615942..615957,-!p1@IRF7!1.89!688.15!IRF7;;chr21:36260295..36260310,-!p3@RUNX1!1.88!117.88!RUNX1;;chr2:231084639..231084654,-!p2@SP110!1.87!118.28!SP110;;chr19:33793430..33793447,-!p1@CEBPA!1.82!260.30!CEBPA;;chr6:106534230..106534254,+!p2@PRDM1!1.81!155.98!PRDM1;;chr19:50432132..50432217,+!p2@ATF5!1.80!73.00!ATF5;;chr12:54778351..54778378,-!p6@ZNF385A!1.80!62.03!ZNF385A;;chr16:79634624..79634642,-!p1@MAF!1.78!225.00!MAF;;chr1:221052776..221052799,+!p1@HLX!1.76!98.93!HLX;;chr11:47400032..47400043,-!p5@SPI1!1.73!52.46!SPI1;;chr16:31885093..31885165,+!p1@ZNF267!1.64!620.93!ZNF267;;chr21:30671690..30671762,+!p2@BACH1!1.64!140.42!BACH1;;chr17:45810594..45810608,+!p1@TBX21!1.64!42.88!TBX21;;chr2:97202480..97202499,+!p1@ARID5A!1.63!402.12!ARID5A;;chr14:75988771..75988826,+!p1@BATF!1.62!53.66!BATF;;chr1:158979872..158979898,+!p3@IFI16!1.61!119.08!IFI16;;chr1:25256439..25256476,-!p3@RUNX3!1.61!39.49!RUNX3;;chr6:391743..391759,+!p1@IRF4!1.60!38.90!IRF4;;chr2:145277640..145277771,-!p1@ZEB2!1.59!486.49!ZEB2;;chr11:615570..615721,-!p2@IRF7!1.58!71.61!IRF7;;chr14:75988831..75988847,+!p2@BATF!1.58!37.10!BATF;;chr2:68592394..68592405,+!p2@PLEK!1.56!35.70!PLEK;;chr1:158985493..158985535,+!p4@IFI16!1.55!51.86!IFI16;;chr16:79634595..79634620,-!p2@MAF!1.54!59.64!MAF;;chr1:221052733..221052749,+!p2@HLX!1.54!43.08!HLX;;chr4:185395590..185395627,-!p3@IRF2!1.53!40.49!IRF2;;chr12:11802753..11802834,+!p2@ETV6!1.51!147.60!ETV6;;chr7:50344289..50344323,+!p1@IKZF1!1.51!31.32!IKZF1;;chr10:51572408..51572454,+!p3@NCOA4!1.50!173.73!NCOA4;;chr10:51572339..51572376,+!p4@NCOA4!1.50!67.42!NCOA4;;chr6:144385698..144385742,-!p2@PLAGL1!1.50!37.10!PLAGL1;;chr21:36421535..36421610,-!p2@RUNX1!1.47!99.73!RUNX1;;chr12:48298765..48298783,-!p2@VDR!1.47!57.84!VDR;;chr10:31288398..31288455,-!p2@ZNF438!1.47!33.31!ZNF438;;chrX:129244454..129244488,-!p1@ELF4!1.46!193.48!ELF4;;chr11:47400045..47400060,-!p6@SPI1!1.46!28.12!SPI1;;chr21:30671235..30671253,+!p1@BACH1!1.44!325.92!BACH1;;chr2:145275162..145275202,-!p2@ZEB2!1.44!149.80!ZEB2;;chr4:185395633..185395651,-!p2@IRF2!1.44!42.29!IRF2;;chr2:231084820..231084836,-!p5@SP110!1.44!30.72!SP110;;chr7:150946376..150946389,-!p6@SMARCD3!1.44!26.53!SMARCD3;;chr9:110250697..110250738,-!p2@KLF4!1.43!30.12!KLF4;;chrX:129244430..129244442,-!p5@ELF4!1.43!26.13!ELF4;;chr12:56415246..56415286,+!p2@IKZF4!1.43!25.73!IKZF4;;chr1:158979922..158979933,+!p13@IFI16!1.38!22.74!IFI16;;chr11:47399920..47399931,-!p7@SPI1!1.37!22.54!SPI1;;chr1:212782094..212782109,+!p1@ATF3!1.36!573.46!ATF3;;chr18:3449720..3449749,+!p2@TGIF1!1.36!45.48!TGIF1;;chr10:35484090..35484104,+!p6@CREM!1.36!21.74!CREM;;chr13:41593425..41593480,-!p1@ELF1!1.34!128.85!ELF1;;chr12:48298785..48298828,-!p1@VDR!1.34!109.11!VDR;;chr12:72056749..72056767,+!p6@THAP2!1.34!23.34!THAP2;;chr21:30672433..30672464,+!p6@BACH1!1.34!20.94!BACH1;;chr19:45251395..45251432,+!p8@BCL3!1.34!20.74!BCL3;;chr6:106535598..106535637,+!p7@PRDM1!1.33!20.54!PRDM1;;chr19:45971246..45971265,+!p1@FOSB!1.32!356.04!FOSB;;chr11:65430554..65430579,-!p3@RELA!1.31!48.67!RELA;;chr14:35872453..35872485,-!p2@NFKBIA!1.31!47.67!NFKBIA;;chr10:31288370..31288393,-!p3@ZNF438!1.31!19.55!ZNF438;;chr9:110252035..110252057,-!p1@KLF4!1.30!291.42!KLF4;;chr2:231090471..231090504,+!p2@SP140!1.30!19.15!SP140;;chr2:231090433..231090469,+!p1@SP140!1.29!18.55!SP140;;chr3:187455680..187455700,-!p4@BCL6!1.28!17.95!BCL6;;chr21:34398234..34398250,+!p1@OLIG2!1.28!17.95!OLIG2;;chr7:28725740..28725778,+!p1@CREB5!1.27!153.39!CREB5;;chr19:45252008..45252024,+!p2@BCL3!1.27!56.85!BCL3;;chr19:45250948..45250998,+!p3@BCL3!1.27!43.68!BCL3;;chr21:36260343..36260402,-!p6@RUNX1!1.27!28.12!RUNX1;;chr22:38597987..38598021,+!p2@MAFF!1.25!101.13!MAFF;;chr12:72056773..72056796,+!p3@THAP2!1.25!21.94!THAP2;;chr17:38497662..38497713,+!p4@RARA!1.25!19.35!RARA;;chr7:149470641..149470694,-!p1@ZNF467!1.24!73.20!ZNF467;;chr2:231084659..231084721,-!p1@SP110!1.23!365.82!SP110;;chr16:3285119..3285133,-!p2@ZNF200!1.23!32.11!ZNF200;;chr12:72056800..72056834,+!p1@THAP2!1.23!21.74!THAP2;;chr12:54694758..54694805,-!p1@NFE2!1.22!18.95!NFE2;;chr21:34442540..34442560,+!p2@OLIG1!1.22!15.76!OLIG1;;chr3:187455486..187455504,-!p6@BCL6!1.22!15.56!BCL6;;chr4:106068026..106068084,+!p1@TET2!1.21!134.24!TET2;;chr16:89787973..89788001,+!p3@ZNF276!1.21!29.12!ZNF276;;chr1:221053049..221053075,+!p3@HLX!1.21!26.13!HLX;;chr21:36260325..36260341,-!p14@RUNX1!1.21!15.36!RUNX1;;chr3:187455634..187455651,-!p7@BCL6!1.21!15.36!BCL6;;chr21:30672734..30672748,+!p11@BACH1!1.20!14.76!BACH1;;chr11:65430535..65430549,-!p4@RELA!1.19!16.95!RELA;;chr20:48807351..48807384,+!p1@CEBPB!1.18!1425.57!CEBPB;;chr1:158979792..158979814,+!p2@IFI16!1.18!133.84!IFI16;;chr2:70314240..70314256,+!p4@PCBP1!1.18!29.32!PCBP1;;chr12:56415287..56415300,+!p5@IKZF4!1.18!13.96!IKZF4;;chr1:8484007..8484061,-!p13@RERE!1.17!17.55!RERE;;chr14:74226747..74226779,-!p3@C14orf43!1.16!75.00!C14orf43;;chr2:238600933..238600985,+!p3@LRRFIP1!1.16!72.80!LRRFIP1;;chr3:12329397..12329433,+!p2@PPARG!1.16!30.72!PPARG;;chr19:19496539..19496576,+!p8@GATAD2A!1.16!23.54!GATAD2A;;chr1:221052840..221052875,+!p4@HLX!1.16!15.96!HLX;;chrX:153305787..153305807,-!p3@MECP2!1.16!13.56!MECP2;;chr7:115670792..115670797,-!p2@TFEC!1.16!13.56!TFEC;;chr4:103422499..103422632,+!p1@NFKB1!1.15!269.87!NFKB1;;chr2:231280954..231280965,+!p2@SP100!1.15!24.33!SP100;;chr2:145277882..145277967,-!p3@ZEB2!1.15!22.74!ZEB2;;chr2:238600998..238601013,+!p5@LRRFIP1!1.15!12.97!LRRFIP1;;chr7:17338266..17338282,+!p1@AHR!1.14!138.43!AHR;;chr12:96588279..96588299,+!p4@ELK3!1.14!61.04!ELK3;;chr6:126240463..126240489,+!p6@NCOA7!1.14!14.56!NCOA7;;chr10:35484804..35484902,+!p2@CREM!1.13!47.87!CREM;;chr12:54785074..54785122,-!p2@ZNF385A!1.13!19.15!ZNF385A;;chr16:79634581..79634592,-!p4@MAF!1.12!12.17!MAF;;chr3:187463179..187463201,-!p2@BCL6!1.11!49.47!BCL6;;chr1:221052994..221053008,+!p6@HLX!1.11!14.16!HLX;;chr3:107318229..107318239,+!p17@BBX!1.11!11.97!BBX;;chr6:36355486..36355497,-!p3@ETV7!1.11!11.97!ETV7;;chr3:39195037..39195069,-!p2@CSRNP1!1.10!72.21!CSRNP1;;chr2:70167296..70167306,+!p3@MXD1!1.10!17.75!MXD1;;chr10:104155480..104155534,+!p2@NFKB2!1.09!74.20!NFKB2;;chr8:116681123..116681143,-!p4@TRPS1!1.09!21.74!TRPS1;;chr16:79633682..79633694,-!p12@MAF!1.09!11.17!MAF;;chr19:45251943..45252006,+!p1@BCL3!1.08!293.21!BCL3;;chr18:3449586..3449617,+!p8@TGIF1!1.08!17.55!TGIF1;;chr19:13213662..13213686,-!p1@LYL1!1.08!16.56!LYL1;;chr1:158985686..158985719,+!p15@IFI16!1.08!10.97!IFI16;;chr3:107318352..107318392,+!p14@BBX!1.08!10.97!BBX;;chr3:187455529..187455544,-!p5@BCL6!1.08!10.97!BCL6;;chr21:36260980..36261011,-!p1@RUNX1!1.07!313.36!RUNX1;;chr6:44233252..44233296,-!p1@NFKBIE!1.07!107.71!NFKBIE;;chr19:45254529..45254561,+!p10@BCL3!1.07!14.56!BCL3;;chr1:221053526..221053540,+!p13@HLX!1.07!10.77!HLX;;chr1:25291620..25291635,-!p4@RUNX3!1.07!10.77!RUNX3;;chr6:106535687..106535706,+!p8@PRDM1!1.07!10.77!PRDM1;;chr2:191885737..191885750,-!p4@STAT1!1.07!10.77!STAT1;;chr12:56753869..56753930,-!p1@STAT2!1.06!461.16!STAT2;;chr1:158979851..158979865,+!p5@IFI16!1.06!23.34!IFI16;;chr3:170075436..170075520,+!p1@SKIL!1.05!221.40!SKIL;;chr9:129567282..129567353,+!p1@ZBTB43!1.05!136.43!ZBTB43;;chr9:3525727..3525828,-!p2@RFX3!1.05!26.33!RFX3;;chr2:145275228..145275241,-!p11@ZEB2!1.05!12.37!ZEB2;;chr12:96588219..96588263,+!p2@ELK3!1.04!73.20!ELK3;;chr6:15246200..15246214,+!p2@JARID2!1.04!27.73!JARID2;;chr19:36391434..36391450,-!p1@NFKBID!1.04!19.95!NFKBID;;chr3:39195139..39195150,-!p3@CSRNP1!1.04!12.77!CSRNP1;;chr2:70142189..70142223,+!p2@MXD1!1.03!70.81!MXD1;;chr14:74226961..74227020,-!p1@C14orf43!1.03!64.83!C14orf43;;chr17:79885537..79885554,-!p2@MAFG!1.03!18.75!MAFG;;chr17:38474489..38474548,+!p1@RARA!1.02!304.38!RARA;;chr18:3449695..3449712,+!p9@TGIF1!1.02!14.76!TGIF1;;chr13:41593392..41593403,-!p7@ELF1!1.02!9.57!ELF1;;chr10:104154246..104154347,+!p3@NFKB2!1.01!58.24!NFKB2;;chr3:63898321..63898396,+!p3@ATXN7!1.01!21.54!ATXN7;;chr8:71316428..71316459,-!p2@NCOA2!1.01!15.56!NCOA2;;chr19:45254508..45254528,+!p12@BCL3!1.01!10.17!BCL3;;chr1:221054922..221054933,+!p16@HLX!1.01!9.18!HLX;;chr5:71803177..71803255,-!p1@ZNF366!1.01!9.18!ZNF366;;chr7:17338324..17338341,+!p3@AHR!1.00!30.72!AHR;;chr2:28618532..28618610,+!p4@FOSL2!1.00!15.76!FOSL2;;chr14:35873947..35873965,-!p1@NFKBIA!0.99!566.48!NFKBIA;;chr19:42636586..42636607,-!p1@POU2F2!0.99!24.73!POU2F2;;chr18:3448455..3448480,+!p5@TGIF1!0.99!16.56!TGIF1;;chr17:79881332..79881348,-!p3@MAFG!0.99!12.97!MAFG;;chr12:54785054..54785072,-!p4@ZNF385A!0.99!9.97!ZNF385A;;chr12:96588368..96588394,+!p3@ELK3!0.98!23.54!ELK3;;chr20:48807456..48807475,+!p3@CEBPB!0.98!16.75!CEBPB;;chr20:48807615..48807644,+!p6@CEBPB!0.98!14.56!CEBPB;;chr18:3449618..3449634,+!p13@TGIF1!0.98!10.57!TGIF1;;chr10:3827371..3827386,-!p2@KLF6!0.97!73.00!KLF6;;chr7:150974206..150974255,-!p1@SMARCD3!0.97!53.66!SMARCD3;;chr21:36259445..36259519,-!p4@RUNX1!0.97!24.14!RUNX1;;chr6:126240380..126240430,+!p2@NCOA7!0.97!21.94!NCOA7;;chr2:185463247..185463263,+!p1@ZNF804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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000222;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000234;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000576;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000763;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000766;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000860;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002193;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002390;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002405 | |||
|ffid_belonging_in_development=CL:0000049,CL:0000134,CL:0002057 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 41: | ||
|fonse_treatment=EFO:0000369,FF:0000629,FF:0011443,FF:11871-125B8 | |fonse_treatment=EFO:0000369,FF:0000629,FF:0011443,FF:11871-125B8 | ||
|fonse_treatment_closure=EFO:0000369,FF:0000629,FF:0011443,FF:11871-125B8 | |fonse_treatment_closure=EFO:0000369,FF:0000629,FF:0011443,FF:11871-125B8 | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520IFN%2520%252b%2520N-hexane%252c%2520donor2.CNhs13476.11871-125B8.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520IFN%2520%252b%2520N-hexane%252c%2520donor2.CNhs13476.11871-125B8.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520IFN%2520%252b%2520N-hexane%252c%2520donor2.CNhs13476.11871-125B8.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520IFN%2520%252b%2520N-hexane%252c%2520donor2.CNhs13476.11871-125B8.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520IFN%2520%252b%2520N-hexane%252c%2520donor2.CNhs13476.11871-125B8.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11871-125B8 | |||
|is_a=EFO:0002091;;FF:0011443 | |||
|is_obsolete= | |||
|library_id=CNhs13476 | |||
|library_id_phase_based=2:CNhs13476 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11871 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11871 | |||
|name=CD14+ monocytes - treated with IFN + N-hexane, donor2 | |||
|namespace= | |namespace= | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs13476,LSID1024,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
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| |||
|rna_box=125 | |||
|rna_catalog_number= | |||
|rna_concentration=0.84782 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number=D4-2 | |||
|rna_od260/230=1.61 | |||
|rna_od260/280=2.03 | |||
|rna_position=B8 | |||
|rna_rin=9.1 | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=125B8 | |||
|rna_weight_ug=3.81519 | |||
|sample_age=51 | |||
|sample_category=primary cells | |||
|sample_cell_catalog= | |||
|sample_cell_line= | |||
|sample_cell_lot= | |||
|sample_cell_type=monocyte | |||
|sample_collaboration=Christine Wells (University of Queensland) | |||
|sample_company= | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease= | |||
|sample_donor(cell lot)=donor2 | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;9.17242088768697e-263!GO:0005737;cytoplasm;7.11401567866828e-131!GO:0043227;membrane-bound organelle;1.69796946097964e-120!GO:0043231;intracellular membrane-bound organelle;3.79420541549473e-120!GO:0043226;organelle;1.53302713681077e-112!GO:0043229;intracellular organelle;1.10358049285301e-111!GO:0044444;cytoplasmic part;1.62495752825209e-85!GO:0044422;organelle part;6.4337088186417e-70!GO:0044446;intracellular organelle part;2.47019996440063e-68!GO:0005515;protein binding;1.1747120477e-67!GO:0044237;cellular metabolic process;1.21326539759064e-67!GO:0044238;primary metabolic process;1.45137848288233e-66!GO:0043170;macromolecule metabolic process;7.05645671716766e-66!GO:0032991;macromolecular complex;1.20916096307028e-59!GO:0003723;RNA binding;1.42017879742541e-56!GO:0030529;ribonucleoprotein complex;2.40559652880002e-52!GO:0019538;protein metabolic process;2.04309422151615e-50!GO:0005634;nucleus;3.98913879588212e-49!GO:0044428;nuclear part;4.3349260517871e-47!GO:0044267;cellular protein metabolic process;7.64593107683268e-47!GO:0044260;cellular macromolecule metabolic process;3.25629810030687e-46!GO:0033036;macromolecule localization;1.06656944083791e-44!GO:0045184;establishment of protein localization;1.68965949850499e-43!GO:0015031;protein transport;2.44603736153204e-43!GO:0008104;protein localization;7.35811014924681e-42!GO:0006412;translation;2.93353101459835e-41!GO:0043233;organelle lumen;3.53615378146143e-38!GO:0031974;membrane-enclosed lumen;3.53615378146143e-38!GO:0043283;biopolymer metabolic process;1.60344815463493e-35!GO:0005829;cytosol;2.19531843239972e-35!GO:0010467;gene expression;6.66494118552003e-34!GO:0031090;organelle membrane;3.57351378998704e-33!GO:0006396;RNA processing;2.92193946137863e-31!GO:0006915;apoptosis;3.74829854574345e-31!GO:0012501;programmed cell death;4.3594748434935e-31!GO:0016071;mRNA metabolic process;5.30010914395892e-31!GO:0009059;macromolecule biosynthetic process;7.40872499232376e-30!GO:0043234;protein complex;7.8436767880018e-30!GO:0008219;cell death;9.0150680089594e-30!GO:0016265;death;9.0150680089594e-30!GO:0046907;intracellular transport;4.39895830484809e-29!GO:0031981;nuclear lumen;7.85185473725532e-29!GO:0008380;RNA splicing;3.13447494969884e-28!GO:0016043;cellular component organization and biogenesis;3.58303405386818e-28!GO:0006886;intracellular protein transport;3.69068013990966e-28!GO:0005739;mitochondrion;1.07770974416371e-27!GO:0044249;cellular biosynthetic process;1.91664294642309e-27!GO:0005840;ribosome;2.05662155518621e-27!GO:0009058;biosynthetic process;6.42944704482172e-27!GO:0006397;mRNA processing;1.3844197214564e-26!GO:0031967;organelle envelope;8.43121711317612e-26!GO:0031975;envelope;1.64587187735509e-25!GO:0003735;structural constituent of ribosome;3.63197620823644e-25!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.1175846947357e-24!GO:0005830;cytosolic ribosome (sensu Eukaryota);6.25938888447104e-24!GO:0033279;ribosomal subunit;1.23839624983052e-23!GO:0051649;establishment of cellular localization;5.57200696170135e-23!GO:0051641;cellular localization;2.77303044519812e-22!GO:0000166;nucleotide binding;2.84360188591512e-22!GO:0065003;macromolecular complex assembly;9.59831201592909e-22!GO:0042981;regulation of apoptosis;1.5863691692254e-21!GO:0044445;cytosolic part;2.37304579011719e-21!GO:0043067;regulation of programmed cell death;3.76603107628919e-21!GO:0005681;spliceosome;8.24935427310652e-21!GO:0044429;mitochondrial part;1.69314310305524e-20!GO:0005654;nucleoplasm;4.97714534746234e-20!GO:0008134;transcription factor binding;2.11841970481676e-19!GO:0006512;ubiquitin cycle;7.53673660603116e-19!GO:0022607;cellular component assembly;2.12734016090475e-18!GO:0016192;vesicle-mediated transport;6.31562470344334e-18!GO:0043412;biopolymer modification;1.02546813285439e-17!GO:0007243;protein kinase cascade;1.61526250105708e-17!GO:0002376;immune system process;1.88824672862193e-17!GO:0044265;cellular macromolecule catabolic process;2.10677098191077e-17!GO:0022613;ribonucleoprotein complex biogenesis and assembly;2.12735026088135e-17!GO:0006119;oxidative phosphorylation;4.89405784793695e-17!GO:0048770;pigment granule;8.26175883681415e-17!GO:0042470;melanosome;8.26175883681415e-17!GO:0044451;nucleoplasm part;8.84628040955888e-17!GO:0032553;ribonucleotide binding;9.41988848640062e-17!GO:0032555;purine ribonucleotide binding;9.41988848640062e-17!GO:0006464;protein modification process;1.89316777047611e-16!GO:0016462;pyrophosphatase activity;3.1432321599045e-16!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;3.21800227862075e-16!GO:0005740;mitochondrial envelope;3.54818836316112e-16!GO:0016817;hydrolase activity, acting on acid anhydrides;4.49981502156784e-16!GO:0043687;post-translational protein modification;8.06062479906115e-16!GO:0017111;nucleoside-triphosphatase activity;9.05337509670571e-16!GO:0007249;I-kappaB kinase/NF-kappaB cascade;9.08511963065835e-16!GO:0017076;purine nucleotide binding;1.00380220443589e-15!GO:0048523;negative regulation of cellular process;1.10970989492602e-15!GO:0031966;mitochondrial membrane;1.10970989492602e-15!GO:0003676;nucleic acid binding;1.41311845319526e-15!GO:0005773;vacuole;1.75320318502741e-15!GO:0019941;modification-dependent protein catabolic process;1.87035901365935e-15!GO:0043632;modification-dependent macromolecule catabolic process;1.87035901365935e-15!GO:0022618;protein-RNA complex assembly;2.29583737978576e-15!GO:0051603;proteolysis involved in cellular protein catabolic process;2.38870437942225e-15!GO:0044257;cellular protein catabolic process;2.8011277621827e-15!GO:0043285;biopolymer catabolic process;3.39583783457435e-15!GO:0006511;ubiquitin-dependent protein catabolic process;3.63507382095682e-15!GO:0016070;RNA metabolic process;6.56271737980157e-15!GO:0019866;organelle inner membrane;8.65930311441581e-15!GO:0016874;ligase activity;1.38509464029798e-14!GO:0006955;immune response;1.81816413285655e-14!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;1.93772123236971e-14!GO:0006605;protein targeting;2.31077688734107e-14!GO:0007242;intracellular signaling cascade;3.11547130031919e-14!GO:0000323;lytic vacuole;3.4781387876063e-14!GO:0005764;lysosome;3.4781387876063e-14!GO:0009057;macromolecule catabolic process;9.44242012222247e-14!GO:0050794;regulation of cellular process;9.74880712863434e-14!GO:0048519;negative regulation of biological process;1.11976177091807e-13!GO:0006996;organelle organization and biogenesis;1.43818387251367e-13!GO:0044248;cellular catabolic process;2.19242834726239e-13!GO:0016604;nuclear body;2.38299029697584e-13!GO:0006913;nucleocytoplasmic transport;3.44677343668222e-13!GO:0043069;negative regulation of programmed cell death;3.78888231070809e-13!GO:0043066;negative regulation of apoptosis;4.70049672621206e-13!GO:0051169;nuclear transport;6.54820534702995e-13!GO:0005768;endosome;8.12058454328533e-13!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;8.90398048564741e-13!GO:0005794;Golgi apparatus;8.95209980531518e-13!GO:0000502;proteasome complex (sensu Eukaryota);9.87148068259945e-13!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.08083226546195e-12!GO:0015934;large ribosomal subunit;1.09578633477003e-12!GO:0012505;endomembrane system;1.6362397403464e-12!GO:0006793;phosphorus metabolic process;1.77131715763432e-12!GO:0006796;phosphate metabolic process;1.77131715763432e-12!GO:0030163;protein catabolic process;2.42263231182289e-12!GO:0008135;translation factor activity, nucleic acid binding;2.54139467280085e-12!GO:0005743;mitochondrial inner membrane;3.54057877881252e-12!GO:0006457;protein folding;3.68986632061361e-12!GO:0003712;transcription cofactor activity;5.19517680001794e-12!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);5.48487763438921e-12!GO:0051246;regulation of protein metabolic process;6.36034062696765e-12!GO:0015935;small ribosomal subunit;7.79782414559662e-12!GO:0009615;response to virus;9.42123515172348e-12!GO:0016607;nuclear speck;1.00561588051958e-11!GO:0005524;ATP binding;1.4240750857295e-11!GO:0044455;mitochondrial membrane part;1.66543287931259e-11!GO:0032559;adenyl ribonucleotide binding;2.06105447811109e-11!GO:0006366;transcription from RNA polymerase II promoter;3.12781381475094e-11!GO:0016310;phosphorylation;4.04837666376871e-11!GO:0050789;regulation of biological process;5.18575939955328e-11!GO:0003743;translation initiation factor activity;5.74215579597094e-11!GO:0006259;DNA metabolic process;5.87287726602885e-11!GO:0065009;regulation of a molecular function;7.68701065010196e-11!GO:0006916;anti-apoptosis;8.23366742874976e-11!GO:0006950;response to stress;1.50438391182431e-10!GO:0030554;adenyl nucleotide binding;1.88187603253356e-10!GO:0006413;translational initiation;2.03039693817956e-10!GO:0009967;positive regulation of signal transduction;4.28546353945231e-10!GO:0051186;cofactor metabolic process;5.32184373714889e-10!GO:0006446;regulation of translational initiation;7.04169550040681e-10!GO:0005635;nuclear envelope;7.52383668221949e-10!GO:0051082;unfolded protein binding;7.69406491053626e-10!GO:0005783;endoplasmic reticulum;7.98941071892806e-10!GO:0019787;small conjugating protein ligase activity;8.72590597452875e-10!GO:0008639;small protein conjugating enzyme activity;9.66315290874676e-10!GO:0048522;positive regulation of cellular process;9.87221598781096e-10!GO:0048193;Golgi vesicle transport;1.08771969093596e-09!GO:0005746;mitochondrial respiratory chain;1.13966838072841e-09!GO:0004842;ubiquitin-protein ligase activity;1.6098603100807e-09!GO:0031324;negative regulation of cellular metabolic process;1.63445964733801e-09!GO:0043065;positive regulation of apoptosis;1.76275523028071e-09!GO:0005730;nucleolus;2.18602602928052e-09!GO:0048518;positive regulation of biological process;2.33364044315598e-09!GO:0043068;positive regulation of programmed cell death;2.8920072632508e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;3.41468746532842e-09!GO:0006732;coenzyme metabolic process;3.41785277459047e-09!GO:0017038;protein import;3.661110182108e-09!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;3.75340197103551e-09!GO:0000398;nuclear mRNA splicing, via spliceosome;3.93904175793959e-09!GO:0000375;RNA splicing, via transesterification reactions;3.93904175793959e-09!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;3.93904175793959e-09!GO:0050136;NADH dehydrogenase (quinone) activity;6.02631014961245e-09!GO:0003954;NADH dehydrogenase activity;6.02631014961245e-09!GO:0008137;NADH dehydrogenase (ubiquinone) activity;6.02631014961245e-09!GO:0016787;hydrolase activity;6.0776826798079e-09!GO:0065007;biological regulation;6.32454583833974e-09!GO:0005770;late endosome;6.79987653356688e-09!GO:0016881;acid-amino acid ligase activity;7.78777379684128e-09!GO:0015986;ATP synthesis coupled proton transport;1.00658198719774e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.00658198719774e-08!GO:0006417;regulation of translation;1.20438476760563e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.2484854015667e-08!GO:0051170;nuclear import;1.37339247321227e-08!GO:0009056;catabolic process;1.42252295815597e-08!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.99330409952955e-08!GO:0019829;cation-transporting ATPase activity;2.44116253340376e-08!GO:0005525;GTP binding;2.52643535268472e-08!GO:0006606;protein import into nucleus;2.91673077960193e-08!GO:0009892;negative regulation of metabolic process;4.70937382684283e-08!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;5.41504582465175e-08!GO:0031965;nuclear membrane;5.45102789932639e-08!GO:0042623;ATPase activity, coupled;5.81194591354757e-08!GO:0003924;GTPase activity;5.87756836595638e-08!GO:0009607;response to biotic stimulus;5.87756836595638e-08!GO:0009152;purine ribonucleotide biosynthetic process;5.98434539011772e-08!GO:0006917;induction of apoptosis;6.26430611231154e-08!GO:0042775;organelle ATP synthesis coupled electron transport;6.42659030302742e-08!GO:0042773;ATP synthesis coupled electron transport;6.42659030302742e-08!GO:0016564;transcription repressor activity;6.49179211269552e-08!GO:0009150;purine ribonucleotide metabolic process;6.74290057736081e-08!GO:0019899;enzyme binding;6.88268142547944e-08!GO:0006164;purine nucleotide biosynthetic process;7.01468957283154e-08!GO:0006163;purine nucleotide metabolic process;7.19019310409141e-08!GO:0007264;small GTPase mediated signal transduction;7.66143530307772e-08!GO:0009259;ribonucleotide metabolic process;7.684774514499e-08!GO:0016887;ATPase activity;7.79659604855335e-08!GO:0009966;regulation of signal transduction;9.9143175632886e-08!GO:0008047;enzyme activator activity;1.02178024741951e-07!GO:0012502;induction of programmed cell death;1.04051687099313e-07!GO:0016481;negative regulation of transcription;1.08890549915466e-07!GO:0007049;cell cycle;1.08890549915466e-07!GO:0030964;NADH dehydrogenase complex (quinone);1.08890549915466e-07!GO:0045271;respiratory chain complex I;1.08890549915466e-07!GO:0005747;mitochondrial respiratory chain complex I;1.08890549915466e-07!GO:0003713;transcription coactivator activity;1.10238132169175e-07!GO:0006754;ATP biosynthetic process;1.17708726322215e-07!GO:0006753;nucleoside phosphate metabolic process;1.17708726322215e-07!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.40320201518223e-07!GO:0044453;nuclear membrane part;1.43206547273297e-07!GO:0009260;ribonucleotide biosynthetic process;1.64132118569761e-07!GO:0005793;ER-Golgi intermediate compartment;1.76167083353031e-07!GO:0005774;vacuolar membrane;1.99179510151292e-07!GO:0043228;non-membrane-bound organelle;2.20649673294433e-07!GO:0043232;intracellular non-membrane-bound organelle;2.20649673294433e-07!GO:0050790;regulation of catalytic activity;2.22117646143484e-07!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;2.22117646143484e-07!GO:0044432;endoplasmic reticulum part;2.67969131000993e-07!GO:0048468;cell development;2.9157206731879e-07!GO:0006461;protein complex assembly;3.33262606476719e-07!GO:0051726;regulation of cell cycle;3.3887212228095e-07!GO:0008565;protein transporter activity;3.61543452712358e-07!GO:0000074;regulation of progression through cell cycle;4.23109032471814e-07!GO:0031326;regulation of cellular biosynthetic process;4.28077847348065e-07!GO:0009889;regulation of biosynthetic process;4.53387250557394e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;4.53387250557394e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;4.53387250557394e-07!GO:0019222;regulation of metabolic process;4.56901546204194e-07!GO:0044440;endosomal part;5.62978686196706e-07!GO:0010008;endosome membrane;5.62978686196706e-07!GO:0032561;guanyl ribonucleotide binding;6.13722377297604e-07!GO:0019001;guanyl nucleotide binding;6.13722377297604e-07!GO:0016469;proton-transporting two-sector ATPase complex;6.43756768827054e-07!GO:0009142;nucleoside triphosphate biosynthetic process;6.46036711181955e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;6.46036711181955e-07!GO:0046034;ATP metabolic process;7.09754442434631e-07!GO:0051188;cofactor biosynthetic process;7.46869620332247e-07!GO:0009055;electron carrier activity;8.10036917175299e-07!GO:0015078;hydrogen ion transmembrane transporter activity;8.20930566014257e-07!GO:0009108;coenzyme biosynthetic process;9.57120043019271e-07!GO:0044437;vacuolar part;1.00980516244786e-06!GO:0005765;lysosomal membrane;1.11036038844703e-06!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.34484350469272e-06!GO:0009144;purine nucleoside triphosphate metabolic process;1.34484350469272e-06!GO:0031982;vesicle;1.62860797756774e-06!GO:0004386;helicase activity;1.78859902686322e-06!GO:0009199;ribonucleoside triphosphate metabolic process;1.804365573189e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;1.91787889262661e-06!GO:0031980;mitochondrial lumen;2.10202726872365e-06!GO:0005759;mitochondrial matrix;2.10202726872365e-06!GO:0005839;proteasome core complex (sensu Eukaryota);2.11946396734795e-06!GO:0032446;protein modification by small protein conjugation;2.31687768532807e-06!GO:0050657;nucleic acid transport;2.59436266775262e-06!GO:0051236;establishment of RNA localization;2.59436266775262e-06!GO:0050658;RNA transport;2.59436266775262e-06!GO:0045786;negative regulation of progression through cell cycle;2.75159250790423e-06!GO:0006325;establishment and/or maintenance of chromatin architecture;2.89529467618749e-06!GO:0006752;group transfer coenzyme metabolic process;3.09394753148865e-06!GO:0006974;response to DNA damage stimulus;3.63209630550349e-06!GO:0006403;RNA localization;3.756758936193e-06!GO:0016044;membrane organization and biogenesis;3.80575973880778e-06!GO:0016567;protein ubiquitination;3.81577250365965e-06!GO:0009141;nucleoside triphosphate metabolic process;4.07093697279571e-06!GO:0008026;ATP-dependent helicase activity;4.39684465098717e-06!GO:0030695;GTPase regulator activity;5.10470325895924e-06!GO:0016568;chromatin modification;5.49997215406759e-06!GO:0016563;transcription activator activity;5.77332342428725e-06!GO:0006888;ER to Golgi vesicle-mediated transport;5.9904384266036e-06!GO:0042175;nuclear envelope-endoplasmic reticulum network;6.86364786966708e-06!GO:0006323;DNA packaging;7.39893882887869e-06!GO:0005789;endoplasmic reticulum membrane;7.42586353592421e-06!GO:0005643;nuclear pore;8.44366385554275e-06!GO:0004298;threonine endopeptidase activity;1.16391369342615e-05!GO:0031410;cytoplasmic vesicle;1.22305044005155e-05!GO:0005096;GTPase activator activity;1.23184895593295e-05!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.26586449621472e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;1.36029790823562e-05!GO:0016197;endosome transport;1.66449888269821e-05!GO:0003724;RNA helicase activity;1.78856718511339e-05!GO:0031252;leading edge;1.80670906353889e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;1.80670906353889e-05!GO:0015399;primary active transmembrane transporter activity;1.80670906353889e-05!GO:0031988;membrane-bound vesicle;1.88607050017244e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;2.0439633718773e-05!GO:0048475;coated membrane;2.62332641176456e-05!GO:0030117;membrane coat;2.62332641176456e-05!GO:0001816;cytokine production;2.69877599031393e-05!GO:0051028;mRNA transport;3.05661201093143e-05!GO:0031323;regulation of cellular metabolic process;3.98679651649298e-05!GO:0003697;single-stranded DNA binding;4.38091574209799e-05!GO:0006281;DNA repair;4.61170555517995e-05!GO:0031902;late endosome membrane;4.64751616741576e-05!GO:0043566;structure-specific DNA binding;4.64751616741576e-05!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;5.18470556517914e-05!GO:0005769;early endosome;5.28213770909714e-05!GO:0045321;leukocyte activation;5.28266497957645e-05!GO:0032940;secretion by cell;5.46894195910127e-05!GO:0045259;proton-transporting ATP synthase complex;5.73646112725814e-05!GO:0003714;transcription corepressor activity;5.7649746782049e-05!GO:0045892;negative regulation of transcription, DNA-dependent;5.90459386292283e-05!GO:0006357;regulation of transcription from RNA polymerase II promoter;5.97268826365187e-05!GO:0022402;cell cycle process;6.21369330318458e-05!GO:0030120;vesicle coat;6.60825172155085e-05!GO:0030662;coated vesicle membrane;6.60825172155085e-05!GO:0006613;cotranslational protein targeting to membrane;6.62846726816335e-05!GO:0016023;cytoplasmic membrane-bound vesicle;6.68113405546487e-05!GO:0008234;cysteine-type peptidase activity;7.73936565674817e-05!GO:0046930;pore complex;7.7564976702735e-05!GO:0009060;aerobic respiration;7.87795940729322e-05!GO:0030099;myeloid cell differentiation;8.81013905313263e-05!GO:0006401;RNA catabolic process;0.000104447045781714!GO:0004674;protein serine/threonine kinase activity;0.000106212872223018!GO:0051336;regulation of hydrolase activity;0.00011545957080353!GO:0006954;inflammatory response;0.000117948750071157!GO:0000151;ubiquitin ligase complex;0.00011852730363387!GO:0065002;intracellular protein transport across a membrane;0.000120652956384188!GO:0005083;small GTPase regulator activity;0.000124872120469116!GO:0008632;apoptotic program;0.000129097562777632!GO:0000245;spliceosome assembly;0.000129486099902095!GO:0016740;transferase activity;0.000139982976585082!GO:0051168;nuclear export;0.000146099486766868!GO:0043492;ATPase activity, coupled to movement of substances;0.000150825087981622!GO:0030532;small nuclear ribonucleoprotein complex;0.000155619904371681!GO:0051276;chromosome organization and biogenesis;0.00016662793530969!GO:0046822;regulation of nucleocytoplasmic transport;0.000176932797892508!GO:0008186;RNA-dependent ATPase activity;0.000182126807164228!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000184921038088878!GO:0006818;hydrogen transport;0.00020605218990209!GO:0044431;Golgi apparatus part;0.000211745490324029!GO:0051707;response to other organism;0.000221780277069913!GO:0031202;RNA splicing factor activity, transesterification mechanism;0.000223297419200033!GO:0042254;ribosome biogenesis and assembly;0.00022921775252951!GO:0030097;hemopoiesis;0.00023409035356837!GO:0006897;endocytosis;0.000240256649604195!GO:0010324;membrane invagination;0.000240256649604195!GO:0005885;Arp2/3 protein complex;0.000259357168943487!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000277348055457565!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;0.000277886976055184!GO:0051789;response to protein stimulus;0.000295141707460528!GO:0006986;response to unfolded protein;0.000295141707460528!GO:0015992;proton transport;0.000314870961571126!GO:0005057;receptor signaling protein activity;0.000314870961571126!GO:0005798;Golgi-associated vesicle;0.000315029065802141!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000401080638378101!GO:0007265;Ras protein signal transduction;0.000417727663023361!GO:0010468;regulation of gene expression;0.000422466440079532!GO:0009893;positive regulation of metabolic process;0.00043649348238576!GO:0005761;mitochondrial ribosome;0.000458208601167517!GO:0000313;organellar ribosome;0.000458208601167517!GO:0006399;tRNA metabolic process;0.000459247262605138!GO:0007259;JAK-STAT cascade;0.00049350485383945!GO:0051223;regulation of protein transport;0.000520197343199452!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000521627667599214!GO:0004004;ATP-dependent RNA helicase activity;0.000526373562202065!GO:0007040;lysosome organization and biogenesis;0.000547318658624628!GO:0006612;protein targeting to membrane;0.000575528259053006!GO:0051427;hormone receptor binding;0.000582103007803377!GO:0045333;cellular respiration;0.000607397337539044!GO:0009719;response to endogenous stimulus;0.00062076980007715!GO:0060090;molecular adaptor activity;0.000626643103964999!GO:0002757;immune response-activating signal transduction;0.000627764745236024!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;0.000627764745236024!GO:0004812;aminoacyl-tRNA ligase activity;0.000627764745236024!GO:0016875;ligase activity, forming carbon-oxygen bonds;0.000627764745236024!GO:0005637;nuclear inner membrane;0.00065377582175563!GO:0051090;regulation of transcription factor activity;0.000684990887585026!GO:0007033;vacuole organization and biogenesis;0.000684990887585026!GO:0007050;cell cycle arrest;0.000685776088720592!GO:0046983;protein dimerization activity;0.000695583773459488!GO:0030036;actin cytoskeleton organization and biogenesis;0.000723848070871075!GO:0046519;sphingoid metabolic process;0.000735624134237122!GO:0007034;vacuolar transport;0.000737995922117193!GO:0002252;immune effector process;0.000775616507587646!GO:0016281;eukaryotic translation initiation factor 4F complex;0.000786272929821263!GO:0003729;mRNA binding;0.00079689276193397!GO:0006402;mRNA catabolic process;0.00080598943708036!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.000870241334712106!GO:0008654;phospholipid biosynthetic process;0.00087476269059858!GO:0005741;mitochondrial outer membrane;0.000902325943490032!GO:0035257;nuclear hormone receptor binding;0.000912548331991067!GO:0046649;lymphocyte activation;0.000936048117353061!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.000961277664276658!GO:0043038;amino acid activation;0.000985258046044857!GO:0006418;tRNA aminoacylation for protein translation;0.000985258046044857!GO:0043039;tRNA aminoacylation;0.000985258046044857!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.00103142440513877!GO:0002764;immune response-regulating signal transduction;0.00107066700372052!GO:0016301;kinase activity;0.00108267949568214!GO:0016779;nucleotidyltransferase activity;0.00109353183951738!GO:0033157;regulation of intracellular protein transport;0.00115352280151517!GO:0042306;regulation of protein import into nucleus;0.00115352280151517!GO:0007005;mitochondrion organization and biogenesis;0.00115484764546729!GO:0007041;lysosomal transport;0.00115948970578294!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00117864525746158!GO:0001726;ruffle;0.00125703151476106!GO:0006672;ceramide metabolic process;0.00127295160202296!GO:0001775;cell activation;0.00133512649122403!GO:0006952;defense response;0.0013658453345642!GO:0002274;myeloid leukocyte activation;0.00144283247436002!GO:0051338;regulation of transferase activity;0.00146132186911876!GO:0022890;inorganic cation transmembrane transporter activity;0.00148087274813948!GO:0030149;sphingolipid catabolic process;0.00152918604372754!GO:0065004;protein-DNA complex assembly;0.001534261424629!GO:0006350;transcription;0.00157723534649987!GO:0033116;ER-Golgi intermediate compartment membrane;0.0016110115077389!GO:0042110;T cell activation;0.00165978927732581!GO:0009117;nucleotide metabolic process;0.00168485187236928!GO:0006099;tricarboxylic acid cycle;0.00182446644356251!GO:0046356;acetyl-CoA catabolic process;0.00182446644356251!GO:0018193;peptidyl-amino acid modification;0.00186296087073666!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.00186969488759056!GO:0005099;Ras GTPase activator activity;0.00187505869664226!GO:0043623;cellular protein complex assembly;0.00193833222663623!GO:0005667;transcription factor complex;0.00202938926059029!GO:0019221;cytokine and chemokine mediated signaling pathway;0.00208647015725638!GO:0031072;heat shock protein binding;0.00209459213785233!GO:0019882;antigen processing and presentation;0.00213673975924159!GO:0045045;secretory pathway;0.00218607484865388!GO:0006643;membrane lipid metabolic process;0.00220923578472599!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00222776846454591!GO:0002520;immune system development;0.00223772573578007!GO:0042613;MHC class II protein complex;0.00226069761600723!GO:0001817;regulation of cytokine production;0.00229296314276745!GO:0043087;regulation of GTPase activity;0.00230883673040672!GO:0045637;regulation of myeloid cell differentiation;0.00239374970509307!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00249656271103243!GO:0051187;cofactor catabolic process;0.00254444754063189!GO:0043549;regulation of kinase activity;0.00256355442820581!GO:0022415;viral reproductive process;0.00266820942304926!GO:0006468;protein amino acid phosphorylation;0.00270638708394006!GO:0045454;cell redox homeostasis;0.00281624037058991!GO:0031968;organelle outer membrane;0.00310155317716436!GO:0002250;adaptive immune response;0.00314970121620109!GO:0002460;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.00314970121620109!GO:0003725;double-stranded RNA binding;0.00314970121620109!GO:0042990;regulation of transcription factor import into nucleus;0.00323319584218124!GO:0042991;transcription factor import into nucleus;0.00323319584218124!GO:0002429;immune response-activating cell surface receptor signaling pathway;0.00326887261586106!GO:0002521;leukocyte differentiation;0.00336888926250347!GO:0019867;outer membrane;0.00364876525754969!GO:0006607;NLS-bearing substrate import into nucleus;0.00371750447507127!GO:0048534;hemopoietic or lymphoid organ development;0.00391429026054669!GO:0031325;positive regulation of cellular metabolic process;0.00391429026054669!GO:0004197;cysteine-type endopeptidase activity;0.00393359984260268!GO:0019904;protein domain specific binding;0.00405960114739233!GO:0045859;regulation of protein kinase activity;0.00406023464729402!GO:0045941;positive regulation of transcription;0.00414554046845232!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00420046817590844!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00428901036221157!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00428901036221157!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00428901036221157!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.00433094226676802!GO:0000139;Golgi membrane;0.00442375366111752!GO:0051092;activation of NF-kappaB transcription factor;0.00448280331618746!GO:0006084;acetyl-CoA metabolic process;0.00452895008896034!GO:0045893;positive regulation of transcription, DNA-dependent;0.00480591041927848!GO:0043280;positive regulation of caspase activity;0.00485840631365975!GO:0030041;actin filament polymerization;0.00490448445313131!GO:0043281;regulation of caspase activity;0.00521955718812141!GO:0031901;early endosome membrane;0.0052402575153961!GO:0002768;immune response-regulating cell surface receptor signaling pathway;0.00529708680292003!GO:0043085;positive regulation of catalytic activity;0.00530546596257329!GO:0006919;caspase activation;0.00557836332879217!GO:0009109;coenzyme catabolic process;0.00562259500254846!GO:0030029;actin filament-based process;0.00569853190539048!GO:0016072;rRNA metabolic process;0.00571683034504643!GO:0006364;rRNA processing;0.00579448551286395!GO:0005070;SH3/SH2 adaptor activity;0.00582925998182811!GO:0002443;leukocyte mediated immunity;0.0059224527003857!GO:0048487;beta-tubulin binding;0.00598631387817623!GO:0043021;ribonucleoprotein binding;0.00618302206949425!GO:0016251;general RNA polymerase II transcription factor activity;0.00635410712887605!GO:0044262;cellular carbohydrate metabolic process;0.00635410712887605!GO:0006891;intra-Golgi vesicle-mediated transport;0.00641297495524551!GO:0005813;centrosome;0.00647917405775266!GO:0031625;ubiquitin protein ligase binding;0.00701572745982199!GO:0016363;nuclear matrix;0.00710535785679422!GO:0003702;RNA polymerase II transcription factor activity;0.0072792151602654!GO:0030867;rough endoplasmic reticulum membrane;0.00729088040041964!GO:0006333;chromatin assembly or disassembly;0.00760647248110404!GO:0042802;identical protein binding;0.0078511674234465!GO:0019377;glycolipid catabolic process;0.0079165802794723!GO:0004185;serine carboxypeptidase activity;0.00796011591515999!GO:0006352;transcription initiation;0.0079786856801802!GO:0002440;production of molecular mediator of immune response;0.00819657985625176!GO:0032386;regulation of intracellular transport;0.00845680796835487!GO:0006458;'de novo' protein folding;0.00922907187836714!GO:0051084;'de novo' posttranslational protein folding;0.00922907187836714!GO:0008383;manganese superoxide dismutase activity;0.00931499379962123!GO:0001315;age-dependent response to reactive oxygen species;0.00931499379962123!GO:0002682;regulation of immune system process;0.00938460009427706!GO:0051098;regulation of binding;0.0094582596170651!GO:0046966;thyroid hormone receptor binding;0.00948152844138597!GO:0043433;negative regulation of transcription factor activity;0.00966146140960575!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.0101360997769996!GO:0005484;SNAP receptor activity;0.0101902707028576!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0102216892583328!GO:0003690;double-stranded DNA binding;0.0103479473208829!GO:0030134;ER to Golgi transport vesicle;0.010517537522488!GO:0042611;MHC protein complex;0.0108420527345358!GO:0030127;COPII vesicle coat;0.0108476058810034!GO:0012507;ER to Golgi transport vesicle membrane;0.0108476058810034!GO:0048500;signal recognition particle;0.0111299533012785!GO:0002684;positive regulation of immune system process;0.0112542367148465!GO:0000785;chromatin;0.0113678883635982!GO:0050851;antigen receptor-mediated signaling pathway;0.0116507719135153!GO:0009165;nucleotide biosynthetic process;0.0116524893120027!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0116625089899559!GO:0002822;regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.;0.0116625089899559!GO:0002819;regulation of adaptive immune response;0.0116625089899559!GO:0002237;response to molecule of bacterial origin;0.0125119397374169!GO:0006414;translational elongation;0.012544704058328!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0129079909484376!GO:0046467;membrane lipid biosynthetic process;0.0130851203349825!GO:0002467;germinal center formation;0.013804612824464!GO:0030693;caspase activity;0.0139504954438468!GO:0051101;regulation of DNA binding;0.0139575570509406!GO:0045792;negative regulation of cell size;0.0141723217002834!GO:0001819;positive regulation of cytokine production;0.0141858843996893!GO:0051091;positive regulation of transcription factor activity;0.0147459101921138!GO:0032318;regulation of Ras GTPase activity;0.0149965481562982!GO:0032763;regulation of mast cell cytokine production;0.0149965481562982!GO:0032762;mast cell cytokine production;0.0149965481562982!GO:0030224;monocyte differentiation;0.015236840210144!GO:0009611;response to wounding;0.0154869880251893!GO:0006611;protein export from nucleus;0.0155089673674392!GO:0006091;generation of precursor metabolites and energy;0.0156099765463896!GO:0051252;regulation of RNA metabolic process;0.0156099765463896!GO:0030027;lamellipodium;0.015629627650053!GO:0000209;protein polyubiquitination;0.015687379486579!GO:0050778;positive regulation of immune response;0.0158078621578775!GO:0006749;glutathione metabolic process;0.0159157419874919!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0159157419874919!GO:0045047;protein targeting to ER;0.0159157419874919!GO:0050900;leukocyte migration;0.0161142595477011!GO:0005815;microtubule organizing center;0.0162325614396553!GO:0051247;positive regulation of protein metabolic process;0.0171450055652595!GO:0000287;magnesium ion binding;0.0171450055652595!GO:0030308;negative regulation of cell growth;0.0172252849113567!GO:0046466;membrane lipid catabolic process;0.0174181957365544!GO:0006665;sphingolipid metabolic process;0.0176431769406196!GO:0002253;activation of immune response;0.0176431769406196!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0176431769406196!GO:0046479;glycosphingolipid catabolic process;0.0182867012412385!GO:0017166;vinculin binding;0.0184935522260566!GO:0051059;NF-kappaB binding;0.0185560892070607!GO:0030658;transport vesicle membrane;0.0185851638823034!GO:0051049;regulation of transport;0.0186429925970827!GO:0030663;COPI coated vesicle membrane;0.0186429925970827!GO:0030126;COPI vesicle coat;0.0186429925970827!GO:0042108;positive regulation of cytokine biosynthetic process;0.0188810787938634!GO:0030133;transport vesicle;0.018957581955952!GO:0004177;aminopeptidase activity;0.019022042695357!GO:0006354;RNA elongation;0.0192873151365621!GO:0019883;antigen processing and presentation of endogenous antigen;0.0193307571918206!GO:0046979;TAP2 binding;0.0194614995075347!GO:0046977;TAP binding;0.0194614995075347!GO:0046978;TAP1 binding;0.0194614995075347!GO:0008286;insulin receptor signaling pathway;0.0197830971582947!GO:0002444;myeloid leukocyte mediated immunity;0.0199718923954945!GO:0016791;phosphoric monoester hydrolase activity;0.0200846730198395!GO:0048002;antigen processing and presentation of peptide antigen;0.0200846730198395!GO:0030218;erythrocyte differentiation;0.0200846730198395!GO:0008139;nuclear localization sequence binding;0.0201169470952355!GO:0015923;mannosidase activity;0.020118514894527!GO:0004860;protein kinase inhibitor activity;0.020118514894527!GO:0043300;regulation of leukocyte degranulation;0.0201452402916977!GO:0005048;signal sequence binding;0.0208171701435589!GO:0030518;steroid hormone receptor signaling pathway;0.0209333114680071!GO:0050776;regulation of immune response;0.0209701844934951!GO:0030176;integral to endoplasmic reticulum membrane;0.0209730837056445!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0209730837056445!GO:0030137;COPI-coated vesicle;0.0209756315442731!GO:0048471;perinuclear region of cytoplasm;0.0209756315442731!GO:0008637;apoptotic mitochondrial changes;0.0219455844865699!GO:0003746;translation elongation factor activity;0.0223731688953915!GO:0019210;kinase inhibitor activity;0.0223931034817317!GO:0002224;toll-like receptor signaling pathway;0.0228481819603457!GO:0002221;pattern recognition receptor signaling pathway;0.0228481819603457!GO:0033367;protein localization in mast cell secretory granule;0.0233318416123846!GO:0033365;protein localization in organelle;0.0233318416123846!GO:0033371;T cell secretory granule organization and biogenesis;0.0233318416123846!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.0233318416123846!GO:0033375;protease localization in T cell secretory granule;0.0233318416123846!GO:0042629;mast cell granule;0.0233318416123846!GO:0033377;maintenance of protein localization in T cell secretory granule;0.0233318416123846!GO:0033364;mast cell secretory granule organization and biogenesis;0.0233318416123846!GO:0033380;granzyme B localization in T cell secretory granule;0.0233318416123846!GO:0033379;maintenance of protease localization in T cell secretory granule;0.0233318416123846!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.0233318416123846!GO:0033368;protease localization in mast cell secretory granule;0.0233318416123846!GO:0033366;protein localization in secretory granule;0.0233318416123846!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.0233318416123846!GO:0033374;protein localization in T cell secretory granule;0.0233318416123846!GO:0000049;tRNA binding;0.0236111285829699!GO:0008629;induction of apoptosis by intracellular signals;0.0236111285829699!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0241049828407401!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0241049828407401!GO:0043022;ribosome binding;0.0242731173940391!GO:0043071;positive regulation of non-apoptotic programmed cell death;0.0242938538709328!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0244491428594166!GO:0051345;positive regulation of hydrolase activity;0.0250929448722298!GO:0008361;regulation of cell size;0.0255957769786052!GO:0008312;7S RNA binding;0.0255957769786052!GO:0002697;regulation of immune effector process;0.0256333445757245!GO:0030118;clathrin coat;0.0257503933361563!GO:0019783;small conjugating protein-specific protease activity;0.02601424718866!GO:0051085;chaperone cofactor-dependent protein folding;0.0266495537035944!GO:0005694;chromosome;0.0268418837759842!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0268515602155778!GO:0000082;G1/S transition of mitotic cell cycle;0.0274093565166848!GO:0015036;disulfide oxidoreductase activity;0.0274395758475041!GO:0030258;lipid modification;0.0276422617720422!GO:0030503;regulation of cell redox homeostasis;0.0276422617720422!GO:0015631;tubulin binding;0.0277274873780816!GO:0051540;metal cluster binding;0.0278288989683294!GO:0051536;iron-sulfur cluster binding;0.0278288989683294!GO:0002449;lymphocyte mediated immunity;0.0278288989683294!GO:0043488;regulation of mRNA stability;0.0278916966691581!GO:0043487;regulation of RNA stability;0.0278916966691581!GO:0019220;regulation of phosphate metabolic process;0.0287644272719912!GO:0051174;regulation of phosphorus metabolic process;0.0287644272719912!GO:0003727;single-stranded RNA binding;0.0289681164362811!GO:0050811;GABA receptor binding;0.029008790828845!GO:0017091;AU-rich element binding;0.0293101898620185!GO:0050779;RNA destabilization;0.0293101898620185!GO:0000289;poly(A) tail shortening;0.0293101898620185!GO:0043621;protein self-association;0.0293809429696601!GO:0019079;viral genome replication;0.0293809429696601!GO:0005788;endoplasmic reticulum lumen;0.0293809429696601!GO:0006405;RNA export from nucleus;0.0305550630426776!GO:0030660;Golgi-associated vesicle membrane;0.0308439747227478!GO:0030384;phosphoinositide metabolic process;0.0308622937626557!GO:0005791;rough endoplasmic reticulum;0.03101984330693!GO:0051329;interphase of mitotic cell cycle;0.0313392001589221!GO:0006650;glycerophospholipid metabolic process;0.0313633107931902!GO:0009306;protein secretion;0.0313939860315128!GO:0004843;ubiquitin-specific protease activity;0.0315422954581264!GO:0006351;transcription, DNA-dependent;0.0320174787748238!GO:0006465;signal peptide processing;0.0337046520696409!GO:0051056;regulation of small GTPase mediated signal transduction;0.0337743425068812!GO:0045576;mast cell activation;0.0337941364246376!GO:0032774;RNA biosynthetic process;0.0337941364246376!GO:0000278;mitotic cell cycle;0.034023050308697!GO:0042113;B cell activation;0.0340335378236685!GO:0032760;positive regulation of tumor necrosis factor production;0.0342563418970515!GO:0005669;transcription factor TFIID complex;0.0342636696150305!GO:0017015;regulation of transforming growth factor beta receptor signaling pathway;0.0342636696150305!GO:0005684;U2-dependent spliceosome;0.0353988326092616!GO:0019318;hexose metabolic process;0.0354958030826584!GO:0000118;histone deacetylase complex;0.0358010523474419!GO:0051325;interphase;0.0360532816178577!GO:0045449;regulation of transcription;0.036777948605449!GO:0002824;positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0370515346373218!GO:0002821;positive regulation of adaptive immune response;0.0370515346373218!GO:0008270;zinc ion binding;0.037495804661876!GO:0046426;negative regulation of JAK-STAT cascade;0.0376101744062195!GO:0030433;ER-associated protein catabolic process;0.0381341151529939!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0381341151529939!GO:0008538;proteasome activator activity;0.039223510960437!GO:0006516;glycoprotein catabolic process;0.0393666839615959!GO:0030521;androgen receptor signaling pathway;0.0398441068427107!GO:0045113;regulation of integrin biosynthetic process;0.0398441068427107!GO:0045112;integrin biosynthetic process;0.0398441068427107!GO:0046578;regulation of Ras protein signal transduction;0.0400855587214792!GO:0008624;induction of apoptosis by extracellular signals;0.0401429490655268!GO:0008656;caspase activator activity;0.0402256707891945!GO:0051235;maintenance of localization;0.0402256707891945!GO:0033033;negative regulation of myeloid cell apoptosis;0.040308209001286!GO:0001803;regulation of type III hypersensitivity;0.040308209001286!GO:0032733;positive regulation of interleukin-10 production;0.040308209001286!GO:0033025;regulation of mast cell apoptosis;0.040308209001286!GO:0001805;positive regulation of type III hypersensitivity;0.040308209001286!GO:0033023;mast cell homeostasis;0.040308209001286!GO:0002431;Fc receptor mediated stimulatory signaling pathway;0.040308209001286!GO:0033032;regulation of myeloid cell apoptosis;0.040308209001286!GO:0001802;type III hypersensitivity;0.040308209001286!GO:0033028;myeloid cell apoptosis;0.040308209001286!GO:0042590;antigen processing and presentation of exogenous peptide antigen via MHC class I;0.040308209001286!GO:0033026;negative regulation of mast cell apoptosis;0.040308209001286!GO:0033024;mast cell apoptosis;0.040308209001286!GO:0030100;regulation of endocytosis;0.0404804089558049!GO:0002718;regulation of cytokine production during immune response;0.040499367392383!GO:0002367;cytokine production during immune response;0.040499367392383!GO:0002700;regulation of production of molecular mediator of immune response;0.040499367392383!GO:0033673;negative regulation of kinase activity;0.0406119842786023!GO:0006469;negative regulation of protein kinase activity;0.0406119842786023!GO:0019843;rRNA binding;0.0408877976302656!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0408877976302656!GO:0006260;DNA replication;0.0411098269446594!GO:0042348;NF-kappaB import into nucleus;0.0411098269446594!GO:0042345;regulation of NF-kappaB import into nucleus;0.0411098269446594!GO:0006644;phospholipid metabolic process;0.0411098269446594!GO:0019901;protein kinase binding;0.0413580717942318!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0419475495448828!GO:0007162;negative regulation of cell adhesion;0.0422783685438818!GO:0007006;mitochondrial membrane organization and biogenesis;0.0423469236893839!GO:0006376;mRNA splice site selection;0.0429751942909978!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0429751942909978!GO:0000165;MAPKKK cascade;0.0431381904520839!GO:0042116;macrophage activation;0.0439947269568452!GO:0043299;leukocyte degranulation;0.0442860827901696!GO:0035035;histone acetyltransferase binding;0.0443038192460517!GO:0005996;monosaccharide metabolic process;0.0444959390446876!GO:0051251;positive regulation of lymphocyte activation;0.0445777927762173!GO:0048146;positive regulation of fibroblast proliferation;0.0445951392170446!GO:0008154;actin polymerization and/or depolymerization;0.0447572033192756!GO:0005869;dynactin complex;0.0451881613255516!GO:0006984;ER-nuclear signaling pathway;0.0452315290954629!GO:0016311;dephosphorylation;0.0452356040096889!GO:0050871;positive regulation of B cell activation;0.0453872229154227!GO:0003711;transcription elongation regulator activity;0.0453872229154227!GO:0004218;cathepsin S activity;0.0459612848516215!GO:0000339;RNA cap binding;0.0461654847213387!GO:0045926;negative regulation of growth;0.0462986516473201!GO:0043304;regulation of mast cell degranulation;0.0464781469880673!GO:0000738;DNA catabolic process, exonucleolytic;0.0466313434164862!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0470318293585715!GO:0006689;ganglioside catabolic process;0.0477995610787748!GO:0045309;protein phosphorylated amino acid binding;0.0478472406899363!GO:0030217;T cell differentiation;0.0479895241213242!GO:0051348;negative regulation of transferase activity;0.0480841309365224!GO:0006383;transcription from RNA polymerase III promoter;0.0482175006360629!GO:0006509;membrane protein ectodomain proteolysis;0.0484152841655195!GO:0033619;membrane protein proteolysis;0.0484152841655195!GO:0016049;cell growth;0.0485183993602032!GO:0047485;protein N-terminus binding;0.0496981206376241!GO:0000303;response to superoxide;0.0498098854918334 | |||
|sample_id=11871 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue= | |||
|top_motifs=STAT2,4,6:4.74160591604;STAT1,3:4.06598506238;IRF7:3.85716160805;IRF1,2:3.75328749558;STAT5{A,B}:3.74168408721;NFE2L2:2.95468493496;CEBPA,B_DDIT3:2.80190871156;NFE2:2.79277195232;EP300:2.63365478301;SPIB:2.6272047293;SPI1:2.47775447696;NANOG{mouse}:2.47153884679;FOXP3:2.42770893108;FOSL2:2.40856293259;PAX2:2.36971567791;SREBF1,2:2.36875228267;NR1H4:2.17783834131;ETS1,2:2.12728863815;DMAP1_NCOR{1,2}_SMARC:2.05914100919;BACH2:1.95688323662;FOS_FOS{B,L1}_JUN{B,D}:1.85890066415;HLF:1.7121830707;NFIL3:1.66868267344;ATF4:1.66180897924;TLX2:1.64831588853;FOXN1:1.54630028114;RUNX1..3:1.48216677112;TGIF1:1.46454234273;NFE2L1:1.46071818344;ELF1,2,4:1.41621498659;ATF5_CREB3:1.40079519287;ATF6:1.32605923097;NFKB1_REL_RELA:1.19395371435;ALX4:1.15647512963;TFCP2:1.15529070501;CREB1:1.04564345289;ZBTB16:0.973552393681;FOXD3:0.936907238755;HIF1A:0.93632318856;HMX1:0.923019958326;SPZ1:0.848031498439;BPTF:0.84368259574;SMAD1..7,9:0.679812955196;ESRRA:0.66345617741;GLI1..3:0.648895283717;RXRA_VDR{dimer}:0.628128793476;PDX1:0.60810788665;PITX1..3:0.601022729442;NR6A1:0.597501557399;JUN:0.545979447822;FOX{D1,D2}:0.530341400125;HSF1,2:0.498888553027;HMGA1,2:0.480203341594;ATF2:0.456994831744;PAX3,7:0.453190104615;HBP1_HMGB_SSRP1_UBTF:0.415473723802;CDX1,2,4:0.389433346759;MAFB:0.310155266413;GATA4:0.249894319657;FOXO1,3,4:0.206404596581;IKZF2:0.197084772501;FOXP1:0.181870063606;FOX{F1,F2,J1}:0.173567031301;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.145011714756;TOPORS:0.134203095912;AHR_ARNT_ARNT2:0.109341824728;NKX6-1,2:0.107056986238;ESR1:0.0698652621669;PRDM1:0.0510947350078;NANOG:0.00475613816588;RFX2..5_RFXANK_RFXAP:-0.00955691015406;SRF:-0.0570903980325;PAX8:-0.0817821346646;NKX3-2:-0.0983508696932;PAX4:-0.117060474657;EN1,2:-0.133667728394;XBP1:-0.140132718464;MYB:-0.145210737134;HES1:-0.22770368051;NFATC1..3:-0.237578361693;TBP:-0.266787344656;HOX{A6,A7,B6,B7}:-0.29650149921;POU1F1:-0.297179622474;RXR{A,B,G}:-0.324763306759;EGR1..3:-0.332257102828;TFAP4:-0.335628093299;OCT4_SOX2{dimer}:-0.336913354313;RREB1:-0.381486759689;HNF4A_NR2F1,2:-0.43450408887;MYFfamily:-0.463581332423;PPARG:-0.482659172314;MZF1:-0.494785622538;NKX2-2,8:-0.523217420488;RBPJ:-0.524132560998;POU5F1:-0.548959085662;VSX1,2:-0.601205164661;ALX1:-0.611222298814;ZNF238:-0.634172789435;FOXM1:-0.63425380053;MED-1{core}:-0.634591060889;NFIX:-0.650645608362;HOXA9_MEIS1:-0.683066460465;MEF2{A,B,C,D}:-0.716119296196;REST:-0.719872725682;CUX2:-0.731754084785;SOX2:-0.734727072475;IKZF1:-0.737431305621;NHLH1,2:-0.742731417347;HOX{A5,B5}:-0.783923297587;MYOD1:-0.78901999316;PATZ1:-0.798831179074;HNF1A:-0.811247580596;POU2F1..3:-0.868575475517;PRRX1,2:-0.870347230851;TFAP2{A,C}:-0.878712655971;PAX1,9:-0.887579495462;DBP:-0.931174910473;TFAP2B:-0.940712048726;AIRE:-0.941762415572;MTE{core}:-0.96630369909;ZBTB6:-0.975013654923;GATA6:-0.976702694555;MYBL2:-0.994273806606;ZNF148:-0.997889024961;GZF1:-1.00496741647;MTF1:-1.03780902771;TAL1_TCF{3,4,12}:-1.03840373031;SOX5:-1.05536371075;EVI1:-1.0568641636;GCM1,2:-1.0818013068;NKX3-1:-1.10097761679;HAND1,2:-1.1121423928;ZFP161:-1.12150838688;FOXL1:-1.14384909792;KLF4:-1.15051501608;UFEwm:-1.18056959939;NKX2-3_NKX2-5:-1.2044780756;RXR{A,B,G}_{NR1H2,PPAR}dimers:-1.20612427574;PAX6:-1.20699293315;ZEB1:-1.21920971337;MAZ:-1.24177631957;TP53:-1.24446361785;SP1:-1.26843948457;NR3C1:-1.27336795504;XCPE1{core}:-1.28149270609;RORA:-1.33253301566;LMO2:-1.36636098298;GTF2I:-1.37378008352;RFX1:-1.39874231683;CRX:-1.40046698053;BREu{core}:-1.40563531048;POU6F1:-1.41807305899;GTF2A1,2:-1.44093593791;SNAI1..3:-1.44532258957;TLX1..3_NFIC{dimer}:-1.4775712259;FOXA2:-1.48589444594;EBF1:-1.48640842904;E2F1..5:-1.4900870053;ZIC1..3:-1.50976345285;TEAD1:-1.54018864824;ZNF423:-1.56418517769;TFDP1:-1.58413018205;HIC1:-1.62130852064;ELK1,4_GABP{A,B1}:-1.64691805277;T:-1.67004293202;TEF:-1.73415204055;ZNF384:-1.74312203453;NKX2-1,4:-1.79545003057;YY1:-1.79926278161;PAX5:-1.87855441618;SOX{8,9,10}:-1.90544706185;AR:-1.92551092178;bHLH_family:-1.96545401586;GFI1B:-1.97074924205;NR5A1,2:-1.98067293221;ADNP_IRX_SIX_ZHX:-1.99596887495;ONECUT1,2:-2.04698190141;FOX{I1,J2}:-2.07768189024;TBX4,5:-2.11149062271;HOX{A4,D4}:-2.13265328135;CDC5L:-2.16170646414;FOXQ1:-2.19353269238;NFY{A,B,C}:-2.23057056418;POU3F1..4:-2.31038191515;NRF1:-2.41460849533;GFI1:-2.44903067848;SOX17:-2.45690377784;PBX1:-2.66090803963;ARID5B:-2.73597937484;ZNF143:-2.86157247667;LEF1_TCF7_TCF7L1,2:-2.90822213215;LHX3,4:-2.93169508713 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11871-125B8;search_select_hide=table117:FF:11871-125B8 | |||
}} | }} |
Latest revision as of 18:25, 4 June 2020
Name: | CD14+ monocytes - treated with IFN + N-hexane, donor2 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13476 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13476
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13476
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.115 |
10 | 10 | 0.0188 |
100 | 100 | 0.837 |
101 | 101 | 0.868 |
102 | 102 | 0.508 |
103 | 103 | 0.346 |
104 | 104 | 0.665 |
105 | 105 | 0.341 |
106 | 106 | 4.2523e-4 |
107 | 107 | 0.164 |
108 | 108 | 0.969 |
109 | 109 | 0.228 |
11 | 11 | 0.142 |
110 | 110 | 0.185 |
111 | 111 | 0.0255 |
112 | 112 | 0.253 |
113 | 113 | 0.55 |
114 | 114 | 0.0114 |
115 | 115 | 0.305 |
116 | 116 | 0.785 |
117 | 117 | 0.0655 |
118 | 118 | 0.185 |
119 | 119 | 0.131 |
12 | 12 | 0.471 |
120 | 120 | 0.951 |
121 | 121 | 0.549 |
122 | 122 | 0.608 |
123 | 123 | 0.0647 |
124 | 124 | 0.915 |
125 | 125 | 0.395 |
126 | 126 | 0.347 |
127 | 127 | 0.342 |
128 | 128 | 0.0174 |
129 | 129 | 0.506 |
13 | 13 | 0.157 |
130 | 130 | 0.131 |
131 | 131 | 0.584 |
132 | 132 | 0.0727 |
133 | 133 | 0.796 |
134 | 134 | 0.614 |
135 | 135 | 0.43 |
136 | 136 | 0.789 |
137 | 137 | 0.0155 |
138 | 138 | 0.133 |
139 | 139 | 0.0647 |
14 | 14 | 0.354 |
140 | 140 | 0.297 |
141 | 141 | 0.221 |
142 | 142 | 0.2 |
143 | 143 | 0.0754 |
144 | 144 | 0.711 |
145 | 145 | 0.305 |
146 | 146 | 0.584 |
147 | 147 | 0.284 |
148 | 148 | 0.0285 |
149 | 149 | 0.703 |
15 | 15 | 0.132 |
150 | 150 | 0.43 |
151 | 151 | 0.266 |
152 | 152 | 0.0973 |
153 | 153 | 0.647 |
154 | 154 | 0.363 |
155 | 155 | 0.705 |
156 | 156 | 0.575 |
157 | 157 | 0.534 |
158 | 158 | 0.0676 |
159 | 159 | 0.706 |
16 | 16 | 0.258 |
160 | 160 | 0.495 |
161 | 161 | 0.466 |
162 | 162 | 0.282 |
163 | 163 | 0.169 |
164 | 164 | 0.154 |
165 | 165 | 0.0641 |
166 | 166 | 0.679 |
167 | 167 | 0.148 |
168 | 168 | 0.422 |
169 | 169 | 0.00853 |
17 | 17 | 0.201 |
18 | 18 | 0.196 |
19 | 19 | 0.298 |
2 | 2 | 0.951 |
20 | 20 | 0.323 |
21 | 21 | 0.315 |
22 | 22 | 0.265 |
23 | 23 | 0.0372 |
24 | 24 | 0.199 |
25 | 25 | 0.388 |
26 | 26 | 0.0426 |
27 | 27 | 0.92 |
28 | 28 | 0.449 |
29 | 29 | 0.253 |
3 | 3 | 0.0574 |
30 | 30 | 0.573 |
31 | 31 | 0.823 |
32 | 32 | 0.929 |
33 | 33 | 0.371 |
34 | 34 | 0.487 |
35 | 35 | 0.212 |
36 | 36 | 0.138 |
37 | 37 | 0.0719 |
38 | 38 | 0.43 |
39 | 39 | 0.809 |
4 | 4 | 0.956 |
40 | 40 | 0.276 |
41 | 41 | 0.0414 |
42 | 42 | 0.314 |
43 | 43 | 0.042 |
44 | 44 | 0.605 |
45 | 45 | 0.788 |
46 | 46 | 0.14 |
47 | 47 | 0.45 |
48 | 48 | 0.392 |
49 | 49 | 0.116 |
5 | 5 | 0.232 |
50 | 50 | 0.903 |
51 | 51 | 0.384 |
52 | 52 | 0.236 |
53 | 53 | 0.281 |
54 | 54 | 0.261 |
55 | 55 | 0.301 |
56 | 56 | 0.633 |
57 | 57 | 0.68 |
58 | 58 | 0.0938 |
59 | 59 | 0.186 |
6 | 6 | 0.772 |
60 | 60 | 0.0271 |
61 | 61 | 0.544 |
62 | 62 | 0.0389 |
63 | 63 | 0.382 |
64 | 64 | 0.418 |
65 | 65 | 0.266 |
66 | 66 | 0.243 |
67 | 67 | 0.599 |
68 | 68 | 0.751 |
69 | 69 | 0.723 |
7 | 7 | 0.285 |
70 | 70 | 0.0202 |
71 | 71 | 0.0457 |
72 | 72 | 0.141 |
73 | 73 | 0.116 |
74 | 74 | 0.105 |
75 | 75 | 0.106 |
76 | 76 | 0.275 |
77 | 77 | 0.391 |
78 | 78 | 0.0917 |
79 | 79 | 0.0288 |
8 | 8 | 0.399 |
80 | 80 | 0.219 |
81 | 81 | 0.329 |
82 | 82 | 0.0937 |
83 | 83 | 0.311 |
84 | 84 | 0.421 |
85 | 85 | 0.0104 |
86 | 86 | 0.0418 |
87 | 87 | 0.65 |
88 | 88 | 0.48 |
89 | 89 | 0.384 |
9 | 9 | 0.354 |
90 | 90 | 0.0311 |
91 | 91 | 0.257 |
92 | 92 | 0.173 |
93 | 93 | 0.441 |
94 | 94 | 0.0465 |
95 | 95 | 0.387 |
96 | 96 | 0.394 |
97 | 97 | 0.838 |
98 | 98 | 0.0838 |
99 | 99 | 0.142 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13476
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0011443 CD14-positive monocytes - treated with IFN + N-hexane sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000766 (myeloid leukocyte)
0000219 (motile cell)
0000325 (stuff accumulating cell)
0000473 (defensive cell)
0000234 (phagocyte)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0000255 (eukaryotic cell)
0000576 (monocyte)
0000860 (classical monocyte)
0002057 (CD14-positive, CD16-negative classical monocyte)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
0000350 (experimentally modified sample)
0000629 (IFN and N-hexane treatment sample)
0011443 (CD14-positive monocytes - treated with IFN + N-hexane sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)
CL:0002057 (CD14-positive, CD16-negative classical monocyte)