FF:11879-125C7: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00004841 | ||
| | |accession_numbers=CAGE;DRX008136;DRR009008;DRZ000433;DRZ001818;DRZ011783;DRZ013168 | ||
| | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000766,CL:0000219,CL:0000325,CL:0000473,CL:0000234,CL:0000738,CL:0002087,CL:0000255,CL:0000576,CL:0000860,CL:0002057 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001,FF:0000625,FF:0000350,FF:0000630,FF:0011102 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr2:68592406..68592424,+!p1@PLEK!3.17!1464.58!PLEK;;chr11:47400078..47400106,-!p1@SPI1!2.79!610.17!SPI1;;chr21:34442439..34442455,+!p1@OLIG1!2.56!364.29!OLIG1;;chr7:115670804..115670825,-!p1@TFEC!2.44!277.13!TFEC;;chr10:64576105..64576133,-!p1@EGR2!2.38!474.90!EGR2;;chr12:54778471..54778528,-!p1@ZNF385A!2.38!237.66!ZNF385A;;chr16:85932760..85932775,+!p1@IRF8!2.28!189.14!IRF8;;chr11:47399947..47399961,-!p3@SPI1!2.11!127.46!SPI1;;chr20:39317868..39317884,-!p1@MAFB!2.07!1277.91!MAFB;;chr11:47400062..47400077,-!p2@SPI1!2.07!115.54!SPI1;;chr6:106534192..106534224,+!p1@PRDM1!1.96!243.00!PRDM1;;chr21:34398234..34398250,+!p1@OLIG2!1.96!90.87!OLIG2;;chr10:64018918..64018936,+!p2@ZNF365!1.89!76.48!ZNF365;;chr11:47399996..47400014,-!p4@SPI1!1.86!71.54!SPI1;;chr19:50432132..50432217,+!p2@ATF5!1.83!78.94!ATF5;;chr1:25256756..25256774,-!p1@RUNX3!1.81!115.95!RUNX3;;chr11:47400032..47400043,-!p5@SPI1!1.78!58.80!SPI1;;chr10:35484053..35484076,+!p1@CREM!1.76!136.51!CREM;;chr10:31288370..31288393,-!p3@ZNF438!1.76!57.15!ZNF438;;chr10:31288398..31288455,-!p2@ZNF438!1.75!64.55!ZNF438;;chr2:70142232..70142251,+!p1@MXD1!1.74!290.28!MXD1;;chr3:12329397..12329433,+!p2@PPARG!1.72!114.72!PPARG;;chr19:45971246..45971265,+!p1@FOSB!1.71!884.42!FOSB;;chr14:35872453..35872485,-!p2@NFKBIA!1.71!120.06!NFKBIA;;chr9:102584159..102584174,+!p2@NR4A3!1.69!83.88!NR4A3;;chr12:52445218..52445237,+!p1@NR4A1!1.68!560.42!NR4A1;;chr2:157189180..157189290,-!p1@NR4A2!1.68!235.19!NR4A2;;chr12:72056800..72056834,+!p1@THAP2!1.68!62.09!THAP2;;chr2:145277640..145277771,-!p1@ZEB2!1.67!577.69!ZEB2;;chr2:68592394..68592405,+!p2@PLEK!1.67!45.64!PLEK;;chr6:106534230..106534254,+!p2@PRDM1!1.66!108.96!PRDM1;;chr1:212782094..212782109,+!p1@ATF3!1.60!995.85!ATF3;;chr16:31885093..31885165,+!p1@ZNF267!1.59!553.43!ZNF267;;chr2:145275162..145275202,-!p2@ZEB2!1.59!215.86!ZEB2;;chr14:35873947..35873965,-!p1@NFKBIA!1.57!2151.64!NFKBIA;;chr2:61108695..61108753,+!p1@REL!1.57!237.24!REL;;chr22:38597987..38598021,+!p2@MAFF!1.56!208.05!MAFF;;chr8:22550982..22550999,-!p1@EGR3!1.56!96.21!EGR3;;chr12:72056749..72056767,+!p6@THAP2!1.56!38.65!THAP2;;chr20:48599506..48599526,+!p1@SNAI1!1.55!213.40!SNAI1;;chr10:51572408..51572454,+!p3@NCOA4!1.55!192.02!NCOA4;;chr11:47400045..47400060,-!p6@SPI1!1.55!34.54!SPI1;;chr12:54778351..54778378,-!p6@ZNF385A!1.54!33.72!ZNF385A;;chr21:34442540..34442560,+!p2@OLIG1!1.54!33.72!OLIG1;;chr3:12330560..12330579,+!p1@PPARG!1.53!37.83!PPARG;;chr4:103422499..103422632,+!p1@NFKB1!1.51!627.44!NFKB1;;chr19:36391434..36391450,-!p1@NFKBID!1.50!58.39!NFKBID;;chr9:102584128..102584144,+!p3@NR4A3!1.49!56.33!NR4A3;;chr6:15246200..15246214,+!p2@JARID2!1.48!79.36!JARID2;;chr14:35872962..35873025,-!p3@NFKBIA!1.48!72.37!NFKBIA;;chr12:72056773..72056796,+!p3@THAP2!1.48!37.83!THAP2;;chr20:48807351..48807384,+!p1@CEBPB!1.47!2758.94!CEBPB;;chr7:128577972..128578047,+!p1@IRF5!1.47!43.99!IRF5;;chr6:144385698..144385742,-!p2@PLAGL1!1.47!34.54!PLAGL1;;chr6:44233252..44233296,-!p1@NFKBIE!1.45!254.92!NFKBIE;;chr10:104155480..104155534,+!p2@NFKB2!1.45!171.46!NFKB2;;chr9:102584262..102584276,+!p1@NR4A3!1.45!59.62!NR4A3;;chr21:30671690..30671762,+!p2@BACH1!1.44!87.99!BACH1;;chrX:153305787..153305807,-!p3@MECP2!1.44!26.73!MECP2;;chrX:129244454..129244488,-!p1@ELF4!1.42!176.39!ELF4;;chr10:51572339..51572376,+!p4@NCOA4!1.42!55.51!NCOA4;;chr21:30671235..30671253,+!p1@BACH1!1.40!296.45!BACH1;;chr19:54041669..54041697,+!p2@ZNF331!1.40!23.85!ZNF331;;chr19:19496539..19496576,+!p8@GATAD2A!1.39!40.71!GATAD2A;;chr10:104154246..104154347,+!p3@NFKB2!1.36!129.93!NFKB2;;chr7:50344289..50344323,+!p1@IKZF1!1.36!21.79!IKZF1;;chr19:45251395..45251432,+!p8@BCL3!1.36!21.79!BCL3;;chr21:36260295..36260310,-!p3@RUNX1!1.34!33.30!RUNX1;;chr13:41593425..41593480,-!p1@ELF1!1.33!126.64!ELF1;;chr19:33793430..33793447,-!p1@CEBPA!1.32!81.41!CEBPA;;chr19:54058073..54058088,+!p1@ZNF331!1.32!19.74!ZNF331;;chr9:129567282..129567353,+!p1@ZBTB43!1.31!244.64!ZBTB43;;chr2:97202480..97202499,+!p1@ARID5A!1.30!186.26!ARID5A;;chr12:48298765..48298783,-!p2@VDR!1.30!38.65!VDR;;chr6:12012170..12012245,+!p1@HIVEP1!1.28!89.63!HIVEP1;;chr10:104155659..104155676,+!p4@NFKB2!1.28!22.61!NFKB2;;chr4:106068026..106068084,+!p1@TET2!1.27!156.24!TET2;;chr18:3449720..3449749,+!p2@TGIF1!1.27!37.42!TGIF1;;chr11:47399920..47399931,-!p7@SPI1!1.27!17.68!SPI1;;chr11:65430554..65430579,-!p3@RELA!1.26!43.17!RELA;;chr1:221052776..221052799,+!p1@HLX!1.26!30.43!HLX;;chr8:80679993..80680011,-!p1@HEY1!1.26!24.67!HEY1;;chr20:48809000..48809053,+!p12@CEBPB!1.26!22.61!CEBPB;;chr17:38497662..38497713,+!p4@RARA!1.26!19.74!RARA;;chrX:129244430..129244442,-!p5@ELF4!1.26!17.27!ELF4;;chr6:106535598..106535637,+!p7@PRDM1!1.26!17.27!PRDM1;;chr1:38325227..38325246,-!p2@MTF1!1.25!23.03!MTF1;;chr1:37940170..37940190,+!p1@ZC3H12A!1.23!191.60!ZC3H12A;;chr6:12012249..12012266,+!p5@HIVEP1!1.23!27.96!HIVEP1;;chr5:142782823..142782854,-!p3@NR3C1!1.23!22.61!NR3C1;;chr7:17338266..17338282,+!p1@AHR!1.22!165.70!AHR;;chr12:11802753..11802834,+!p2@ETV6!1.22!75.24!ETV6;;chr2:70314240..70314256,+!p4@PCBP1!1.22!31.66!PCBP1;;chr6:391743..391759,+!p1@IRF4!1.22!15.62!IRF4;;chr8:53373491..53373506,-!p4@ST18!1.22!15.62!ST18;;chr1:157108130..157108173,-!p1@ETV3!1.21!108.14!ETV3;;chr21:36421535..36421610,-!p2@RUNX1!1.21!53.45!RUNX1;;chr19:45250948..45250998,+!p3@BCL3!1.21!38.24!BCL3;;chr8:72756637..72756664,-!p3@MSC!1.21!17.27!MSC;;chr2:238600933..238600985,+!p3@LRRFIP1!1.20!78.94!LRRFIP1;;chr19:45252008..45252024,+!p2@BCL3!1.20!48.52!BCL3;;chr8:72756063..72756125,-!p1@MSC!1.20!29.60!MSC;;chr20:48807456..48807475,+!p3@CEBPB!1.20!28.37!CEBPB;;chr19:50432104..50432126,+!p6@ATF5!1.20!14.80!ATF5;;chr1:25256439..25256476,-!p3@RUNX3!1.20!14.80!RUNX3;;chr20:48807648..48807671,+!p9@CEBPB!1.19!20.97!CEBPB;;chr14:35872926..35872951,-!p4@NFKBIA!1.18!19.74!NFKBIA;;chr1:221052733..221052749,+!p2@HLX!1.18!18.50!HLX;;chr10:31288329..31288353,-!p7@ZNF438!1.18!13.98!ZNF438;;chr10:35484090..35484104,+!p6@CREM!1.18!13.98!CREM;;chr7:17338324..17338341,+!p3@AHR!1.17!46.05!AHR;;chr2:192015701..192015743,-!p1@STAT4!1.17!18.91!STAT4;;chr2:28615716..28615733,+!p1@FOSL2!1.16!634.84!FOSL2;;chr3:170075436..170075520,+!p1@SKIL!1.16!289.05!SKIL;;chr12:96588219..96588263,+!p2@ELK3!1.16!97.04!ELK3;;chr2:145277882..145277967,-!p3@ZEB2!1.16!23.44!ZEB2;;chr2:113999360..113999386,-!p4@PAX8!1.16!13.57!PAX8;;chr18:77155922..77155939,+!p1@NFATC1!1.15!35.77!NFATC1;;chr10:3827371..3827386,-!p2@KLF6!1.14!107.31!KLF6;;chr6:12011943..12012015,+!p2@HIVEP1!1.14!41.53!HIVEP1;;chr14:64970670..64970712,-!p3@ZBTB25!1.14!27.96!ZBTB25;;chr6:15246217..15246228,+!p3@JARID2!1.14!22.61!JARID2;;chr2:61108808..61108821,+!p3@REL!1.14!16.04!REL;;chr14:64971014..64971044,+!p4@ZBTB1!1.12!20.15!ZBTB1;;chr18:3449586..3449617,+!p8@TGIF1!1.12!19.32!TGIF1;;chr18:3449618..3449634,+!p13@TGIF1!1.12!15.21!TGIF1;;chr21:30672433..30672464,+!p6@BACH1!1.12!12.34!BACH1;;chr2:238600998..238601013,+!p5@LRRFIP1!1.12!12.34!LRRFIP1;;chr9:110252035..110252057,-!p1@KLF4!1.11!189.55!KLF4;;chr19:19496624..19496660,+!p3@GATAD2A!1.11!54.69!GATAD2A;;chr10:104155455..104155479,+!p1@NFKB2!1.10!168.99!NFKB2;;chr12:48298785..48298828,-!p1@VDR!1.10!61.26!VDR;;chr9:102584241..102584261,+!p4@NR4A3!1.10!18.09!NR4A3;;chr2:61108771..61108789,+!p4@REL!1.10!17.68!REL;;chr2:102091566..102091581,-!p1@RFX8!1.10!11.51!RFX8;;chr2:231090471..231090504,+!p2@SP140!1.10!11.51!SP140;;chr13:41593392..41593403,-!p7@ELF1!1.10!11.51!ELF1;;chr11:615942..615957,-!p1@IRF7!1.09!106.08!IRF7;;chr1:156470515..156470542,-!p2@MEF2D!1.09!60.03!MEF2D;;chr20:48807615..48807644,+!p6@CEBPB!1.09!18.91!CEBPB;;chr6:15246261..15246312,+!p1@JARID2!1.08!267.67!JARID2;;chr3:69788576..69788648,+!p1@MITF!1.08!59.62!MITF;;chr20:48807171..48807234,+!p4@CEBPB!1.08!24.26!CEBPB;;chr2:68615063..68615089,+!p4@PLEK!1.08!11.10!PLEK;;chr3:126191157..126191171,-!p4@ZXDC!1.08!11.10!ZXDC;;chr2:28618532..28618610,+!p4@FOSL2!1.07!18.50!FOSL2;;chr12:96588279..96588299,+!p4@ELK3!1.06!50.16!ELK3;;chr17:79885537..79885554,-!p2@MAFG!1.06!20.56!MAFG;;chr18:3448455..3448480,+!p5@TGIF1!1.06!19.32!TGIF1;;chr7:149470641..149470694,-!p1@ZNF467!1.05!46.87!ZNF467;;chr17:79881332..79881348,-!p3@MAFG!1.05!15.21!MAFG;;chr5:71803177..71803255,-!p1@ZNF366!1.05!10.28!ZNF366;;chr7:115670792..115670797,-!p2@TFEC!1.05!10.28!TFEC;;chr3:101568349..101568365,+!p1@NFKBIZ!1.04!518.89!NFKBIZ;;chr21:36260980..36261011,-!p1@RUNX1!1.04!293.16!RUNX1;;chr17:38474489..38474548,+!p1@RARA!1.03!313.31!RARA;;chr3:12329358..12329393,+!p3@PPARG!1.03!24.26!PPARG;;chr18:3449527..3449582,+!p6@TGIF1!1.03!18.91!TGIF1;;chr18:3449695..3449712,+!p9@TGIF1!1.03!15.21!TGIF1;;chr1:156470494..156470505,-!p3@MEF2D!1.03!14.39!MEF2D;;chr3:39195037..39195069,-!p2@CSRNP1!1.02!60.44!CSRNP1;;chr6:20403916..20403965,+!p3@E2F3!1.02!43.58!E2F3;;chr2:208394817..208394834,+!p3@CREB1!1.02!38.65!CREB1;;chr12:96588368..96588394,+!p3@ELK3!1.02!25.90!ELK3;;chr3:101546827..101546847,+!p2@NFKBIZ!1.02!13.57!NFKBIZ;;chr14:35872494..35872511,-!p5@NFKBIA!1.02!12.75!NFKBIA;;chr2:145277589..145277612,-!p12@ZEB2!1.02!9.46!ZEB2;;chr3:12329464..12329472,+!p6@PPARG!1.02!9.46!PPARG;;chr19:36389839..36389857,-!p4@NFKBID!1.02!9.46!NFKBID;;chr6:106535687..106535706,+!p8@PRDM1!1.02!9.46!PRDM1;;chr21:40177845..40177863,+!p1@ETS2!1.01!550.14!ETS2;;chr2:157198916..157198978,-!p2@NR4A2!1.01!32.89!NR4A2;;chr10:35416142..35416169,+!p3@CREM!1.01!25.08!CREM;;chr20:48807430..48807439,+!p8@CEBPB!1.01!13.98!CEBPB;;chr19:42636586..42636607,-!p1@POU2F2!1.00!25.49!POU2F2;;chr9:110250697..110250738,-!p2@KLF4!1.00!10.69!KLF4;;chr8:72755203..72755239,-!p10@MSC!1.00!9.05!MSC;;chr1:25291620..25291635,-!p4@RUNX3!1.00!9.05!RUNX3;;chrX:153305962..153305995,-!p5@MECP2!1.00!9.05!MECP2;;chr19:45504688..45504782,+!p1@RELB!0.99!55.10!RELB;;chr10:35484804..35484902,+!p2@CREM!0.99!34.54!CREM;;chr8:123793988..123794016,+!p1@ZHX2!0.99!15.62!ZHX2;;chr3:150126101..150126118,+!p6@TSC22D2!0.99!14.39!TSC22D2;;chr3:5021113..5021180,+!p1@BHLHE40!0.98!611.00!BHLHE40;;chr1:935467..935484,-!p1@HES4!0.98!38.65!HES4;;chr4:103423079..103423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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000222;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000234;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000576;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000763;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000766;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000860;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002193;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002390;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002405 | |||
|ffid_belonging_in_development=CL:0000049,CL:0000134,CL:0002057 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 41: | ||
|fonse_treatment=EFO:0000369,FF:0000625,FF:0000630,FF:0011102,FF:11879-125C7 | |fonse_treatment=EFO:0000369,FF:0000625,FF:0000630,FF:0011102,FF:11879-125C7 | ||
|fonse_treatment_closure=EFO:0000369,FF:0000625,FF:0000630,FF:0011102,FF:11879-125C7 | |fonse_treatment_closure=EFO:0000369,FF:0000625,FF:0000630,FF:0011102,FF:11879-125C7 | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520B-glucan%252c%2520donor2.CNhs13489.11879-125C7.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520B-glucan%252c%2520donor2.CNhs13489.11879-125C7.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520B-glucan%252c%2520donor2.CNhs13489.11879-125C7.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520B-glucan%252c%2520donor2.CNhs13489.11879-125C7.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520B-glucan%252c%2520donor2.CNhs13489.11879-125C7.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11879-125C7 | |||
|is_a=EFO:0002091;;FF:0011102 | |||
|is_obsolete= | |||
|library_id=CNhs13489 | |||
|library_id_phase_based=2:CNhs13489 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11879 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11879 | |||
|name=CD14+ monocytes - treated with B-glucan, donor2 | |||
|namespace= | |namespace= | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs13489,LSID1025,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
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| |||
|rna_box=125 | |||
|rna_catalog_number= | |||
|rna_concentration=0.73067 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number=D4-10 | |||
|rna_od260/230=1.52 | |||
|rna_od260/280=2.02 | |||
|rna_position=C7 | |||
|rna_rin=8.8 | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=125C7 | |||
|rna_weight_ug=3.288015 | |||
|sample_age=51 | |||
|sample_category=primary cells | |||
|sample_cell_catalog= | |||
|sample_cell_line= | |||
|sample_cell_lot= | |||
|sample_cell_type=monocyte | |||
|sample_collaboration=Christine Wells (University of Queensland) | |||
|sample_company= | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease= | |||
|sample_donor(cell lot)=donor2 | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;2.19635752422217e-269!GO:0005737;cytoplasm;5.8449984335039e-128!GO:0043227;membrane-bound organelle;4.7052569430969e-116!GO:0043231;intracellular membrane-bound organelle;1.02110484676916e-115!GO:0043226;organelle;2.09732774774566e-108!GO:0043229;intracellular organelle;1.33649212871165e-107!GO:0044444;cytoplasmic part;4.54234422077823e-82!GO:0005515;protein binding;6.50945671221779e-74!GO:0044422;organelle part;3.54321923889136e-68!GO:0044237;cellular metabolic process;7.43553782076549e-67!GO:0044446;intracellular organelle part;1.1806504581467e-66!GO:0044238;primary metabolic process;1.45239326722968e-65!GO:0043170;macromolecule metabolic process;3.55982360597679e-63!GO:0032991;macromolecular complex;8.44653236282966e-57!GO:0003723;RNA binding;1.40779546506736e-52!GO:0030529;ribonucleoprotein complex;2.69205254979205e-50!GO:0019538;protein metabolic process;9.58242928855962e-48!GO:0005634;nucleus;1.57775732008482e-47!GO:0044428;nuclear part;5.66582781116554e-46!GO:0044267;cellular protein metabolic process;1.20760747780653e-44!GO:0044260;cellular macromolecule metabolic process;2.30046241442997e-44!GO:0033036;macromolecule localization;1.63696539279234e-41!GO:0006412;translation;3.26874850966263e-40!GO:0045184;establishment of protein localization;5.49475755097631e-40!GO:0015031;protein transport;6.30485782851214e-40!GO:0008104;protein localization;1.81894218223338e-38!GO:0043233;organelle lumen;5.66418356129815e-37!GO:0031974;membrane-enclosed lumen;5.66418356129815e-37!GO:0005829;cytosol;1.45200399757461e-35!GO:0043283;biopolymer metabolic process;9.90847737108569e-34!GO:0006915;apoptosis;1.39904999674261e-33!GO:0012501;programmed cell death;1.53608400132237e-33!GO:0031090;organelle membrane;1.54120905748519e-33!GO:0010467;gene expression;2.71035796219173e-33!GO:0008219;cell death;5.50102974447538e-32!GO:0016265;death;5.50102974447538e-32!GO:0006396;RNA processing;8.28437034244228e-32!GO:0016071;mRNA metabolic process;2.59884977697561e-31!GO:0009059;macromolecule biosynthetic process;9.18190328265456e-30!GO:0031981;nuclear lumen;1.53358858307999e-29!GO:0044249;cellular biosynthetic process;5.38076597319973e-29!GO:0009058;biosynthetic process;8.86980371425009e-29!GO:0043234;protein complex;2.15364114468453e-28!GO:0016043;cellular component organization and biogenesis;2.17745171577571e-28!GO:0046907;intracellular transport;8.14206149239284e-28!GO:0008380;RNA splicing;2.54143506457354e-27!GO:0006886;intracellular protein transport;6.34787246346941e-27!GO:0006397;mRNA processing;1.12182161190524e-26!GO:0005840;ribosome;1.8075336811655e-26!GO:0005739;mitochondrion;1.79860046886899e-24!GO:0003735;structural constituent of ribosome;2.71389520654813e-24!GO:0031967;organelle envelope;2.95314076808887e-24!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;4.30760222292555e-24!GO:0031975;envelope;5.31679699131355e-24!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.46531888312178e-23!GO:0033279;ribosomal subunit;4.36545831111312e-23!GO:0042981;regulation of apoptosis;1.16437660543186e-22!GO:0043067;regulation of programmed cell death;2.64026025520625e-22!GO:0044445;cytosolic part;1.06267710463834e-21!GO:0065003;macromolecular complex assembly;1.14793882924694e-21!GO:0008134;transcription factor binding;1.40237209510993e-21!GO:0051649;establishment of cellular localization;1.45992548407627e-21!GO:0051641;cellular localization;7.03807682733467e-21!GO:0005654;nucleoplasm;1.73251803157931e-20!GO:0005681;spliceosome;1.8296272206621e-20!GO:0000166;nucleotide binding;1.88123237732674e-19!GO:0044429;mitochondrial part;1.83212402354906e-18!GO:0022607;cellular component assembly;3.80189299636956e-18!GO:0048770;pigment granule;4.31926952296165e-18!GO:0042470;melanosome;4.31926952296165e-18!GO:0022613;ribonucleoprotein complex biogenesis and assembly;5.0814955392827e-18!GO:0048523;negative regulation of cellular process;1.35383998819333e-17!GO:0016192;vesicle-mediated transport;1.36063529102201e-17!GO:0044451;nucleoplasm part;3.09812000356804e-17!GO:0007243;protein kinase cascade;6.61659667765948e-17!GO:0044265;cellular macromolecule catabolic process;1.34053229725067e-16!GO:0006119;oxidative phosphorylation;3.30388653132864e-16!GO:0006512;ubiquitin cycle;4.8051316832808e-16!GO:0048519;negative regulation of biological process;6.09359929338582e-16!GO:0043412;biopolymer modification;6.9092748754902e-16!GO:0005773;vacuole;2.84811342388015e-15!GO:0022618;protein-RNA complex assembly;2.92698048333555e-15!GO:0005740;mitochondrial envelope;3.31060602565975e-15!GO:0043069;negative regulation of programmed cell death;7.90338143972316e-15!GO:0043285;biopolymer catabolic process;8.16585388986711e-15!GO:0050794;regulation of cellular process;8.28336002663228e-15!GO:0043066;negative regulation of apoptosis;8.90902211960772e-15!GO:0006464;protein modification process;9.34591136166312e-15!GO:0007242;intracellular signaling cascade;1.10133544412728e-14!GO:0016070;RNA metabolic process;1.1539904408238e-14!GO:0017111;nucleoside-triphosphatase activity;1.17057198495519e-14!GO:0031966;mitochondrial membrane;1.2975540458743e-14!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.64925944460564e-14!GO:0043687;post-translational protein modification;1.64925944460564e-14!GO:0016462;pyrophosphatase activity;1.66250841472794e-14!GO:0016817;hydrolase activity, acting on acid anhydrides;2.4086986954663e-14!GO:0032553;ribonucleotide binding;2.42796159633793e-14!GO:0032555;purine ribonucleotide binding;2.42796159633793e-14!GO:0002376;immune system process;3.07630151024127e-14!GO:0009057;macromolecule catabolic process;4.69270899771981e-14!GO:0006605;protein targeting;6.65004934266705e-14!GO:0007249;I-kappaB kinase/NF-kappaB cascade;8.00866208449274e-14!GO:0019866;organelle inner membrane;8.83214164413087e-14!GO:0006913;nucleocytoplasmic transport;9.08940063986694e-14!GO:0016604;nuclear body;9.9183256866711e-14!GO:0003712;transcription cofactor activity;1.07239001659975e-13!GO:0006996;organelle organization and biogenesis;1.16259372227204e-13!GO:0019941;modification-dependent protein catabolic process;1.29809745698528e-13!GO:0043632;modification-dependent macromolecule catabolic process;1.29809745698528e-13!GO:0017076;purine nucleotide binding;1.45501528624298e-13!GO:0000323;lytic vacuole;1.52996136898388e-13!GO:0005764;lysosome;1.52996136898388e-13!GO:0044257;cellular protein catabolic process;1.71468215802232e-13!GO:0006511;ubiquitin-dependent protein catabolic process;1.79252458105507e-13!GO:0051603;proteolysis involved in cellular protein catabolic process;1.80160297416211e-13!GO:0051169;nuclear transport;1.85552897632211e-13!GO:0003676;nucleic acid binding;2.17470951104504e-13!GO:0065009;regulation of a molecular function;2.58639678605164e-13!GO:0016874;ligase activity;2.68726988637675e-13!GO:0012505;endomembrane system;4.87147120217609e-13!GO:0006950;response to stress;6.32287860721775e-13!GO:0044248;cellular catabolic process;9.91787629998671e-13!GO:0006366;transcription from RNA polymerase II promoter;1.27471751618751e-12!GO:0015934;large ribosomal subunit;1.48779193022725e-12!GO:0005794;Golgi apparatus;1.49978831714351e-12!GO:0008135;translation factor activity, nucleic acid binding;1.51816326034846e-12!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.56768750688303e-12!GO:0051246;regulation of protein metabolic process;1.75893262130528e-12!GO:0006457;protein folding;2.3250118563048e-12!GO:0050789;regulation of biological process;4.23450257472109e-12!GO:0006793;phosphorus metabolic process;4.41065220604669e-12!GO:0006796;phosphate metabolic process;4.41065220604669e-12!GO:0016607;nuclear speck;4.70388792766871e-12!GO:0006916;anti-apoptosis;5.34478611268624e-12!GO:0000502;proteasome complex (sensu Eukaryota);7.44358426491353e-12!GO:0005768;endosome;7.61104952064987e-12!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;7.65861915871608e-12!GO:0030163;protein catabolic process;9.61857527143218e-12!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.11172433304566e-11!GO:0015935;small ribosomal subunit;1.62502952499292e-11!GO:0005743;mitochondrial inner membrane;2.71607357820353e-11!GO:0003743;translation initiation factor activity;2.96823923948423e-11!GO:0006413;translational initiation;6.6303510778389e-11!GO:0016310;phosphorylation;7.25839893772335e-11!GO:0048522;positive regulation of cellular process;7.96105110913359e-11!GO:0065007;biological regulation;1.14657909093026e-10!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;1.17273086486309e-10!GO:0006955;immune response;1.22577777013212e-10!GO:0044455;mitochondrial membrane part;1.9580083775527e-10!GO:0051186;cofactor metabolic process;2.80684739519624e-10!GO:0006259;DNA metabolic process;3.10970943956078e-10!GO:0006446;regulation of translational initiation;3.35043482668607e-10!GO:0051082;unfolded protein binding;3.73795476011572e-10!GO:0048518;positive regulation of biological process;4.53248515589571e-10!GO:0005783;endoplasmic reticulum;5.14891018540694e-10!GO:0005524;ATP binding;5.29736582785966e-10!GO:0032559;adenyl ribonucleotide binding;6.69976312099581e-10!GO:0005730;nucleolus;7.16518744772175e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;9.46653318289638e-10!GO:0050790;regulation of catalytic activity;1.01960751232754e-09!GO:0006732;coenzyme metabolic process;1.82225117965015e-09!GO:0005770;late endosome;1.84352279925596e-09!GO:0005635;nuclear envelope;1.99732623010232e-09!GO:0031324;negative regulation of cellular metabolic process;2.72956321153369e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;3.13128764759119e-09!GO:0016787;hydrolase activity;3.5509948043738e-09!GO:0043065;positive regulation of apoptosis;3.63739547383672e-09!GO:0019829;cation-transporting ATPase activity;3.73672481532565e-09!GO:0030554;adenyl nucleotide binding;3.77419372454683e-09!GO:0000398;nuclear mRNA splicing, via spliceosome;3.88885778084327e-09!GO:0000375;RNA splicing, via transesterification reactions;3.88885778084327e-09!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;3.88885778084327e-09!GO:0048468;cell development;4.00104064004685e-09!GO:0015986;ATP synthesis coupled proton transport;4.5947176389393e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;4.5947176389393e-09!GO:0043068;positive regulation of programmed cell death;5.22164452769305e-09!GO:0008639;small protein conjugating enzyme activity;6.35534680274174e-09!GO:0048193;Golgi vesicle transport;7.57581103809541e-09!GO:0009056;catabolic process;9.28932999523019e-09!GO:0004842;ubiquitin-protein ligase activity;1.01812613782997e-08!GO:0007049;cell cycle;1.03066552377845e-08!GO:0005746;mitochondrial respiratory chain;1.0927747205424e-08!GO:0019787;small conjugating protein ligase activity;1.22326755916475e-08!GO:0017038;protein import;1.22326755916475e-08!GO:0009967;positive regulation of signal transduction;1.26408948221013e-08!GO:0006417;regulation of translation;1.53435132464609e-08!GO:0051170;nuclear import;1.67095841549579e-08!GO:0019899;enzyme binding;1.7961662152073e-08!GO:0003713;transcription coactivator activity;1.89916510392855e-08!GO:0016564;transcription repressor activity;2.93814750764359e-08!GO:0009152;purine ribonucleotide biosynthetic process;3.05469055059926e-08!GO:0009150;purine ribonucleotide metabolic process;3.48052436744698e-08!GO:0006164;purine nucleotide biosynthetic process;3.61546439411802e-08!GO:0006163;purine nucleotide metabolic process;3.68771758704901e-08!GO:0005774;vacuolar membrane;3.79266149577997e-08!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;3.79266149577997e-08!GO:0006606;protein import into nucleus;3.90887511096345e-08!GO:0009615;response to virus;4.72371552642525e-08!GO:0009892;negative regulation of metabolic process;4.9096345555961e-08!GO:0051726;regulation of cell cycle;5.90702673231351e-08!GO:0015078;hydrogen ion transmembrane transporter activity;6.22699387901653e-08!GO:0042623;ATPase activity, coupled;6.25805156553373e-08!GO:0006754;ATP biosynthetic process;6.45921839892658e-08!GO:0006753;nucleoside phosphate metabolic process;6.45921839892658e-08!GO:0008047;enzyme activator activity;6.57712840085032e-08!GO:0031965;nuclear membrane;7.0724430231063e-08!GO:0000074;regulation of progression through cell cycle;7.69969691420212e-08!GO:0016887;ATPase activity;8.23881543030954e-08!GO:0050136;NADH dehydrogenase (quinone) activity;8.33580101647131e-08!GO:0003954;NADH dehydrogenase activity;8.33580101647131e-08!GO:0008137;NADH dehydrogenase (ubiquinone) activity;8.33580101647131e-08!GO:0009259;ribonucleotide metabolic process;9.69797441856308e-08!GO:0044453;nuclear membrane part;9.98645277761063e-08!GO:0006917;induction of apoptosis;1.12746692837943e-07!GO:0016469;proton-transporting two-sector ATPase complex;1.27365126565411e-07!GO:0045786;negative regulation of progression through cell cycle;1.27365126565411e-07!GO:0019222;regulation of metabolic process;1.56075154102017e-07!GO:0044432;endoplasmic reticulum part;1.56075154102017e-07!GO:0009889;regulation of biosynthetic process;1.61063617969054e-07!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.61253920831988e-07!GO:0016881;acid-amino acid ligase activity;1.64634203823782e-07!GO:0009260;ribonucleotide biosynthetic process;1.67622968033911e-07!GO:0009607;response to biotic stimulus;1.71027489307365e-07!GO:0007264;small GTPase mediated signal transduction;1.81293200291403e-07!GO:0012502;induction of programmed cell death;1.81471756718062e-07!GO:0044437;vacuolar part;1.8942644304086e-07!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.94154173018608e-07!GO:0016481;negative regulation of transcription;1.94725801654527e-07!GO:0051188;cofactor biosynthetic process;2.03379861438149e-07!GO:0008565;protein transporter activity;2.23948071529523e-07!GO:0006461;protein complex assembly;2.58722363230836e-07!GO:0003924;GTPase activity;2.61083465807169e-07!GO:0009108;coenzyme biosynthetic process;2.6390297454393e-07!GO:0005765;lysosomal membrane;2.69273144271096e-07!GO:0031326;regulation of cellular biosynthetic process;3.27663918098485e-07!GO:0043228;non-membrane-bound organelle;3.45683814457401e-07!GO:0043232;intracellular non-membrane-bound organelle;3.45683814457401e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;3.62093169760922e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;3.62093169760922e-07!GO:0009055;electron carrier activity;3.6212784002375e-07!GO:0046034;ATP metabolic process;3.7055289120816e-07!GO:0005793;ER-Golgi intermediate compartment;3.80871142378881e-07!GO:0009966;regulation of signal transduction;4.13339194716163e-07!GO:0009142;nucleoside triphosphate biosynthetic process;4.38417983308806e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;4.38417983308806e-07!GO:0005525;GTP binding;5.46169721072791e-07!GO:0042775;organelle ATP synthesis coupled electron transport;6.29460795745225e-07!GO:0042773;ATP synthesis coupled electron transport;6.29460795745225e-07!GO:0031982;vesicle;7.23803999904322e-07!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;7.3518076324767e-07!GO:0016563;transcription activator activity;8.2248285981723e-07!GO:0044440;endosomal part;8.47294860184888e-07!GO:0010008;endosome membrane;8.47294860184888e-07!GO:0030964;NADH dehydrogenase complex (quinone);9.76171875202813e-07!GO:0045271;respiratory chain complex I;9.76171875202813e-07!GO:0005747;mitochondrial respiratory chain complex I;9.76171875202813e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;9.76171875202813e-07!GO:0009144;purine nucleoside triphosphate metabolic process;9.76171875202813e-07!GO:0009199;ribonucleoside triphosphate metabolic process;1.1341795922373e-06!GO:0003714;transcription corepressor activity;1.23665116487849e-06!GO:0006752;group transfer coenzyme metabolic process;1.30921306645917e-06!GO:0050657;nucleic acid transport;1.75268522928729e-06!GO:0051236;establishment of RNA localization;1.75268522928729e-06!GO:0050658;RNA transport;1.75268522928729e-06!GO:0032446;protein modification by small protein conjugation;1.79170491029357e-06!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.90150607303234e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;1.97175137041741e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;2.09162837111458e-06!GO:0016568;chromatin modification;2.11089005688823e-06!GO:0005643;nuclear pore;2.12260936021112e-06!GO:0006403;RNA localization;2.16612738325089e-06!GO:0016044;membrane organization and biogenesis;2.61119756796046e-06!GO:0006325;establishment and/or maintenance of chromatin architecture;2.8443291441821e-06!GO:0009141;nucleoside triphosphate metabolic process;2.86199985750826e-06!GO:0016567;protein ubiquitination;3.08086894799265e-06!GO:0006357;regulation of transcription from RNA polymerase II promoter;3.79011147888342e-06!GO:0042175;nuclear envelope-endoplasmic reticulum network;4.2887451434064e-06!GO:0005789;endoplasmic reticulum membrane;4.96246625085945e-06!GO:0008026;ATP-dependent helicase activity;4.98285134512475e-06!GO:0031410;cytoplasmic vesicle;5.18813672945322e-06!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;5.97399935735765e-06!GO:0015399;primary active transmembrane transporter activity;5.97399935735765e-06!GO:0031252;leading edge;6.65318294871385e-06!GO:0032561;guanyl ribonucleotide binding;6.95662943926229e-06!GO:0019001;guanyl nucleotide binding;6.95662943926229e-06!GO:0006323;DNA packaging;8.08976864806557e-06!GO:0031988;membrane-bound vesicle;8.58138734294102e-06!GO:0006888;ER to Golgi vesicle-mediated transport;8.59567088130198e-06!GO:0004386;helicase activity;9.18460228870622e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;9.87387252488705e-06!GO:0005096;GTPase activator activity;1.24854196424625e-05!GO:0016197;endosome transport;1.66787395804306e-05!GO:0046930;pore complex;1.70986564517642e-05!GO:0006974;response to DNA damage stimulus;1.80268317688983e-05!GO:0031323;regulation of cellular metabolic process;1.88464587773991e-05!GO:0051789;response to protein stimulus;2.03547636966296e-05!GO:0006986;response to unfolded protein;2.03547636966296e-05!GO:0031902;late endosome membrane;2.0524315445131e-05!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;2.14386916561939e-05!GO:0005839;proteasome core complex (sensu Eukaryota);2.16018325263034e-05!GO:0030695;GTPase regulator activity;2.39237354106456e-05!GO:0051028;mRNA transport;2.42470446067153e-05!GO:0051338;regulation of transferase activity;2.57476774622655e-05!GO:0022402;cell cycle process;2.90596695029423e-05!GO:0006954;inflammatory response;3.09422602639533e-05!GO:0016023;cytoplasmic membrane-bound vesicle;3.18774797986595e-05!GO:0031980;mitochondrial lumen;3.43849478024917e-05!GO:0005759;mitochondrial matrix;3.43849478024917e-05!GO:0005769;early endosome;3.85721658717233e-05!GO:0003724;RNA helicase activity;3.98145943583172e-05!GO:0030120;vesicle coat;4.12455174180429e-05!GO:0030662;coated vesicle membrane;4.12455174180429e-05!GO:0045321;leukocyte activation;4.22515032308161e-05!GO:0048475;coated membrane;4.27771591852853e-05!GO:0030117;membrane coat;4.27771591852853e-05!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;4.51514145464799e-05!GO:0008632;apoptotic program;4.70989506988347e-05!GO:0009893;positive regulation of metabolic process;4.73182611435853e-05!GO:0030099;myeloid cell differentiation;5.08783023212144e-05!GO:0006897;endocytosis;5.15571082811405e-05!GO:0010324;membrane invagination;5.15571082811405e-05!GO:0046519;sphingoid metabolic process;6.07864107981996e-05!GO:0051168;nuclear export;6.07864107981996e-05!GO:0046822;regulation of nucleocytoplasmic transport;6.10158212721996e-05!GO:0043549;regulation of kinase activity;6.36223798382962e-05!GO:0043566;structure-specific DNA binding;6.84301622773563e-05!GO:0051336;regulation of hydrolase activity;7.11704982752521e-05!GO:0043492;ATPase activity, coupled to movement of substances;7.49296423647974e-05!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;7.70987760111924e-05!GO:0001816;cytokine production;8.01322282893346e-05!GO:0004298;threonine endopeptidase activity;8.49236499098305e-05!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;9.08486188261305e-05!GO:0045859;regulation of protein kinase activity;0.000100568338164991!GO:0042254;ribosome biogenesis and assembly;0.000102236116794572!GO:0006401;RNA catabolic process;0.000105842003215831!GO:0006672;ceramide metabolic process;0.00010876544463489!GO:0051427;hormone receptor binding;0.000116328580378466!GO:0030036;actin cytoskeleton organization and biogenesis;0.000122151356522784!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000127333332633519!GO:0006281;DNA repair;0.00012748660120653!GO:0006613;cotranslational protein targeting to membrane;0.000130778485878155!GO:0030097;hemopoiesis;0.000136828249676447!GO:0045259;proton-transporting ATP synthase complex;0.000149951347238384!GO:0003697;single-stranded DNA binding;0.000150387378323826!GO:0022890;inorganic cation transmembrane transporter activity;0.000152701385703703!GO:0051223;regulation of protein transport;0.000156251658395753!GO:0004674;protein serine/threonine kinase activity;0.000159344078401772!GO:0006818;hydrogen transport;0.000160152862382267!GO:0046983;protein dimerization activity;0.000162334505565006!GO:0007265;Ras protein signal transduction;0.000177259560374826!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000190663433924724!GO:0005083;small GTPase regulator activity;0.00019135939640745!GO:0035257;nuclear hormone receptor binding;0.000197994485669016!GO:0007050;cell cycle arrest;0.000209447344777856!GO:0016740;transferase activity;0.00022241099348682!GO:0009060;aerobic respiration;0.00023466453767749!GO:0044431;Golgi apparatus part;0.000238473093483534!GO:0005057;receptor signaling protein activity;0.000247076589001951!GO:0030532;small nuclear ribonucleoprotein complex;0.00025376825231657!GO:0001726;ruffle;0.000255321243328043!GO:0005885;Arp2/3 protein complex;0.000261088699129138!GO:0015992;proton transport;0.000267074893291093!GO:0065002;intracellular protein transport across a membrane;0.000267074893291093!GO:0000151;ubiquitin ligase complex;0.000273274140842249!GO:0051276;chromosome organization and biogenesis;0.000273274140842249!GO:0043085;positive regulation of catalytic activity;0.000276598159449058!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000307133893202406!GO:0045892;negative regulation of transcription, DNA-dependent;0.000310932493941006!GO:0010468;regulation of gene expression;0.000331579491461396!GO:0000245;spliceosome assembly;0.000335981288918467!GO:0007033;vacuole organization and biogenesis;0.000340072338803551!GO:0032940;secretion by cell;0.000348678513025191!GO:0008186;RNA-dependent ATPase activity;0.000361037139714606!GO:0060090;molecular adaptor activity;0.000361454824092295!GO:0007040;lysosome organization and biogenesis;0.000361454824092295!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;0.000419064786997028!GO:0004812;aminoacyl-tRNA ligase activity;0.000419064786997028!GO:0016875;ligase activity, forming carbon-oxygen bonds;0.000419064786997028!GO:0031202;RNA splicing factor activity, transesterification mechanism;0.000432251090972161!GO:0003729;mRNA binding;0.000455674895920002!GO:0045941;positive regulation of transcription;0.000476494209376466!GO:0007034;vacuolar transport;0.000482062317031589!GO:0007041;lysosomal transport;0.000496992620113408!GO:0002757;immune response-activating signal transduction;0.000496992620113408!GO:0006952;defense response;0.000539671686900066!GO:0033157;regulation of intracellular protein transport;0.000569341588478757!GO:0042306;regulation of protein import into nucleus;0.000569341588478757!GO:0006402;mRNA catabolic process;0.000583566773777681!GO:0046649;lymphocyte activation;0.000592020302644181!GO:0016281;eukaryotic translation initiation factor 4F complex;0.000608975501538579!GO:0045333;cellular respiration;0.000629079211782349!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000636880210173943!GO:0005798;Golgi-associated vesicle;0.000644408610912006!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.00064574712691496!GO:0045893;positive regulation of transcription, DNA-dependent;0.000658468640644726!GO:0022415;viral reproductive process;0.000660229800289225!GO:0030149;sphingolipid catabolic process;0.000726443124284974!GO:0043038;amino acid activation;0.000751941129657539!GO:0006418;tRNA aminoacylation for protein translation;0.000751941129657539!GO:0043039;tRNA aminoacylation;0.000751941129657539!GO:0009117;nucleotide metabolic process;0.000775197581483732!GO:0031325;positive regulation of cellular metabolic process;0.000781409014070192!GO:0009719;response to endogenous stimulus;0.000809243958736817!GO:0001775;cell activation;0.000820146445114273!GO:0002764;immune response-regulating signal transduction;0.000848072855974855!GO:0016301;kinase activity;0.000990679949316181!GO:0019904;protein domain specific binding;0.00100443161515014!GO:0005741;mitochondrial outer membrane;0.001010808462631!GO:0018193;peptidyl-amino acid modification;0.0010299814624506!GO:0004004;ATP-dependent RNA helicase activity;0.00103597844122329!GO:0051707;response to other organism;0.001062030950892!GO:0005099;Ras GTPase activator activity;0.00112829051167635!GO:0002520;immune system development;0.00115214404489786!GO:0019221;cytokine and chemokine mediated signaling pathway;0.0011537884524915!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00116635197297927!GO:0031072;heat shock protein binding;0.00119656521468604!GO:0006399;tRNA metabolic process;0.0012722657654802!GO:0044262;cellular carbohydrate metabolic process;0.00127632893697332!GO:0002521;leukocyte differentiation;0.00129859581310837!GO:0030029;actin filament-based process;0.00131063554361791!GO:0033116;ER-Golgi intermediate compartment membrane;0.00134110012623607!GO:0002274;myeloid leukocyte activation;0.00136520010644086!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.00136707272913032!GO:0045637;regulation of myeloid cell differentiation;0.00136801052350289!GO:0006919;caspase activation;0.00142525896736192!GO:0048534;hemopoietic or lymphoid organ development;0.00150084405605694!GO:0006643;membrane lipid metabolic process;0.00150444648482531!GO:0005667;transcription factor complex;0.00151670754718706!GO:0042990;regulation of transcription factor import into nucleus;0.00163748315193168!GO:0042991;transcription factor import into nucleus;0.00163748315193168!GO:0043623;cellular protein complex assembly;0.00163748315193168!GO:0006350;transcription;0.00166731338213371!GO:0065004;protein-DNA complex assembly;0.00173499039140569!GO:0005761;mitochondrial ribosome;0.00173499039140569!GO:0000313;organellar ribosome;0.00173499039140569!GO:0051090;regulation of transcription factor activity;0.00175166856260585!GO:0043087;regulation of GTPase activity;0.00179759797502036!GO:0005637;nuclear inner membrane;0.00181031565916889!GO:0008654;phospholipid biosynthetic process;0.0018861939807366!GO:0007005;mitochondrion organization and biogenesis;0.00193168782650321!GO:0006612;protein targeting to membrane;0.0020679724239649!GO:0016072;rRNA metabolic process;0.00214221015819847!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.00215285472524909!GO:0002429;immune response-activating cell surface receptor signaling pathway;0.00219596794681761!GO:0042110;T cell activation;0.00220702163762677!GO:0009611;response to wounding;0.00238649248093241!GO:0016251;general RNA polymerase II transcription factor activity;0.0027161457800925!GO:0045454;cell redox homeostasis;0.0027161457800925!GO:0048487;beta-tubulin binding;0.00282341263685756!GO:0008234;cysteine-type peptidase activity;0.00282341263685756!GO:0031901;early endosome membrane;0.00282341263685756!GO:0043281;regulation of caspase activity;0.0028567438070623!GO:0043280;positive regulation of caspase activity;0.00289401900846288!GO:0006364;rRNA processing;0.0029319455885817!GO:0019867;outer membrane;0.00341729483150493!GO:0005070;SH3/SH2 adaptor activity;0.00357641367781078!GO:0008383;manganese superoxide dismutase activity;0.00357641367781078!GO:0001315;age-dependent response to reactive oxygen species;0.00357641367781078!GO:0002768;immune response-regulating cell surface receptor signaling pathway;0.00357820540360049!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00360996710059231!GO:0042802;identical protein binding;0.00369482078636226!GO:0009165;nucleotide biosynthetic process;0.00369858332999063!GO:0031968;organelle outer membrane;0.00378326640513205!GO:0042613;MHC class II protein complex;0.00402118739564303!GO:0001817;regulation of cytokine production;0.00429371181046503!GO:0019377;glycolipid catabolic process;0.00435562132726175!GO:0031625;ubiquitin protein ligase binding;0.00467149548034261!GO:0007259;JAK-STAT cascade;0.00480719494117518!GO:0032386;regulation of intracellular transport;0.00484425071593188!GO:0006099;tricarboxylic acid cycle;0.00490456389275246!GO:0046356;acetyl-CoA catabolic process;0.00490456389275246!GO:0000139;Golgi membrane;0.00490792452598127!GO:0046966;thyroid hormone receptor binding;0.00510824684603881!GO:0006468;protein amino acid phosphorylation;0.00517611119919474!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.00533466026332098!GO:0051187;cofactor catabolic process;0.00563047793205828!GO:0006665;sphingolipid metabolic process;0.00570851882102499!GO:0006749;glutathione metabolic process;0.00577112554820692!GO:0002252;immune effector process;0.00599441814919581!GO:0006352;transcription initiation;0.00606863021514828!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00639543946019048!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00639543946019048!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00639543946019048!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00639543946019048!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.00642622412507553!GO:0006333;chromatin assembly or disassembly;0.00676092933711958!GO:0016791;phosphoric monoester hydrolase activity;0.00684457817945997!GO:0000082;G1/S transition of mitotic cell cycle;0.00700325422810223!GO:0046479;glycosphingolipid catabolic process;0.00708704657321183!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00735343775966462!GO:0016363;nuclear matrix;0.0074188560161653!GO:0033673;negative regulation of kinase activity;0.00764163129947545!GO:0006469;negative regulation of protein kinase activity;0.00764163129947545!GO:0019220;regulation of phosphate metabolic process;0.00781263866812597!GO:0051174;regulation of phosphorus metabolic process;0.00781263866812597!GO:0006891;intra-Golgi vesicle-mediated transport;0.0079654341575065!GO:0006607;NLS-bearing substrate import into nucleus;0.0081528666593315!GO:0019079;viral genome replication;0.00816923591624067!GO:0006611;protein export from nucleus;0.00821971182210453!GO:0001819;positive regulation of cytokine production;0.00844984957097353!GO:0004185;serine carboxypeptidase activity;0.00845209142526133!GO:0003690;double-stranded DNA binding;0.00858894639329795!GO:0051348;negative regulation of transferase activity;0.00882070952418155!GO:0051098;regulation of binding;0.00893120528303076!GO:0006091;generation of precursor metabolites and energy;0.00893532637702458!GO:0030218;erythrocyte differentiation;0.00894593328039434!GO:0030503;regulation of cell redox homeostasis;0.0091443892828287!GO:0048471;perinuclear region of cytoplasm;0.00920284016927207!GO:0051252;regulation of RNA metabolic process;0.00927404711878894!GO:0045045;secretory pathway;0.00932964173810924!GO:0003702;RNA polymerase II transcription factor activity;0.00946310689510022!GO:0046466;membrane lipid catabolic process;0.00958741071388032!GO:0050851;antigen receptor-mediated signaling pathway;0.00965943537514958!GO:0008139;nuclear localization sequence binding;0.00971919158511354!GO:0006458;'de novo' protein folding;0.0110335908551719!GO:0051084;'de novo' posttranslational protein folding;0.0110335908551719!GO:0000339;RNA cap binding;0.0110995638365527!GO:0006084;acetyl-CoA metabolic process;0.0111221673554632!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0111899390474866!GO:0030127;COPII vesicle coat;0.0113777951724219!GO:0012507;ER to Golgi transport vesicle membrane;0.0113777951724219!GO:0043021;ribonucleoprotein binding;0.0116254803093337!GO:0050900;leukocyte migration;0.0121992619803593!GO:0032318;regulation of Ras GTPase activity;0.0123369099068373!GO:0030134;ER to Golgi transport vesicle;0.0123931154786188!GO:0004860;protein kinase inhibitor activity;0.0124556054400033!GO:0004197;cysteine-type endopeptidase activity;0.0126549824264268!GO:0051049;regulation of transport;0.0126567762684483!GO:0030518;steroid hormone receptor signaling pathway;0.0127442599230636!GO:0030521;androgen receptor signaling pathway;0.0127442599230636!GO:0005048;signal sequence binding;0.0127476718949722!GO:0002444;myeloid leukocyte mediated immunity;0.0128725652071227!GO:0009109;coenzyme catabolic process;0.0131535173512064!GO:0043621;protein self-association;0.0132787490124254!GO:0030041;actin filament polymerization;0.0135465847693308!GO:0008637;apoptotic mitochondrial changes;0.0136452618695811!GO:0043433;negative regulation of transcription factor activity;0.0137210083815055!GO:0051345;positive regulation of hydrolase activity;0.0139531220880384!GO:0030867;rough endoplasmic reticulum membrane;0.0141572825583284!GO:0045639;positive regulation of myeloid cell differentiation;0.0144493659932615!GO:0002822;regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.;0.0149541028715357!GO:0002819;regulation of adaptive immune response;0.0149541028715357!GO:0019882;antigen processing and presentation;0.0153149087806336!GO:0051092;activation of NF-kappaB transcription factor;0.0155123192593819!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0155452522705694!GO:0004177;aminopeptidase activity;0.0157114873606322!GO:0030258;lipid modification;0.0157854569035552!GO:0030658;transport vesicle membrane;0.0158130840518931!GO:0016779;nucleotidyltransferase activity;0.0161492163228846!GO:0030027;lamellipodium;0.016713549870143!GO:0017166;vinculin binding;0.0168416682904984!GO:0000209;protein polyubiquitination;0.0169555360579887!GO:0032763;regulation of mast cell cytokine production;0.0171317718132894!GO:0032762;mast cell cytokine production;0.0171317718132894!GO:0033367;protein localization in mast cell secretory granule;0.0171317718132894!GO:0033365;protein localization in organelle;0.0171317718132894!GO:0033371;T cell secretory granule organization and biogenesis;0.0171317718132894!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.0171317718132894!GO:0033375;protease localization in T cell secretory granule;0.0171317718132894!GO:0042629;mast cell granule;0.0171317718132894!GO:0033377;maintenance of protein localization in T cell secretory granule;0.0171317718132894!GO:0033364;mast cell secretory granule organization and biogenesis;0.0171317718132894!GO:0033380;granzyme B localization in T cell secretory granule;0.0171317718132894!GO:0033379;maintenance of protease localization in T cell secretory granule;0.0171317718132894!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.0171317718132894!GO:0033368;protease localization in mast cell secretory granule;0.0171317718132894!GO:0033366;protein localization in secretory granule;0.0171317718132894!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.0171317718132894!GO:0033374;protein localization in T cell secretory granule;0.0171317718132894!GO:0008286;insulin receptor signaling pathway;0.0172423569456334!GO:0002440;production of molecular mediator of immune response;0.0176465293791095!GO:0002250;adaptive immune response;0.0176503178266054!GO:0002460;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0176503178266054!GO:0005813;centrosome;0.0178484794602353!GO:0045646;regulation of erythrocyte differentiation;0.0179407962181098!GO:0051059;NF-kappaB binding;0.0180254379969161!GO:0005484;SNAP receptor activity;0.0180383656845227!GO:0048500;signal recognition particle;0.0181371473594329!GO:0003725;double-stranded RNA binding;0.018400791960801!GO:0050811;GABA receptor binding;0.0185757328307426!GO:0019318;hexose metabolic process;0.0186703685828808!GO:0019210;kinase inhibitor activity;0.0189546453399313!GO:0019058;viral infectious cycle;0.0191365793291233!GO:0045576;mast cell activation;0.0191903240259!GO:0008361;regulation of cell size;0.0194211956088847!GO:0043488;regulation of mRNA stability;0.0195424547252713!GO:0043487;regulation of RNA stability;0.0195424547252713!GO:0048872;homeostasis of number of cells;0.0202757360285356!GO:0002443;leukocyte mediated immunity;0.0203950612917232!GO:0030663;COPI coated vesicle membrane;0.0206297800576824!GO:0030126;COPI vesicle coat;0.0206297800576824!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0211559751929027!GO:0000165;MAPKKK cascade;0.021566825773646!GO:0006354;RNA elongation;0.0218120546516291!GO:0005996;monosaccharide metabolic process;0.02197906482868!GO:0051347;positive regulation of transferase activity;0.02197906482868!GO:0019843;rRNA binding;0.0224587250200441!GO:0048146;positive regulation of fibroblast proliferation;0.0228005932949441!GO:0006405;RNA export from nucleus;0.022971182411789!GO:0030176;integral to endoplasmic reticulum membrane;0.022971182411789!GO:0006689;ganglioside catabolic process;0.0232455658454335!GO:0051101;regulation of DNA binding;0.0234461170741798!GO:0043022;ribosome binding;0.0234968773492976!GO:0000785;chromatin;0.0245264304875278!GO:0042348;NF-kappaB import into nucleus;0.0246052713244417!GO:0042345;regulation of NF-kappaB import into nucleus;0.0246052713244417!GO:0000287;magnesium ion binding;0.0248573869872334!GO:0051050;positive regulation of transport;0.025024861390713!GO:0051247;positive regulation of protein metabolic process;0.0250935904272162!GO:0035035;histone acetyltransferase binding;0.0254415061139401!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0256906542208141!GO:0045047;protein targeting to ER;0.0256906542208141!GO:0030660;Golgi-associated vesicle membrane;0.0257702862060701!GO:0043300;regulation of leukocyte degranulation;0.0259641321340474!GO:0002237;response to molecule of bacterial origin;0.0260391541386561!GO:0017091;AU-rich element binding;0.0261715006034585!GO:0050779;RNA destabilization;0.0261715006034585!GO:0000289;poly(A) tail shortening;0.0261715006034585!GO:0033549;MAP kinase phosphatase activity;0.0261715006034585!GO:0017017;MAP kinase tyrosine/serine/threonine phosphatase activity;0.0261715006034585!GO:0045792;negative regulation of cell size;0.02653814433338!GO:0042325;regulation of phosphorylation;0.0268542735471338!GO:0015923;mannosidase activity;0.0271484788257848!GO:0048144;fibroblast proliferation;0.0271484788257848!GO:0048145;regulation of fibroblast proliferation;0.0271484788257848!GO:0042221;response to chemical stimulus;0.0271853443075032!GO:0015631;tubulin binding;0.027466858366969!GO:0045449;regulation of transcription;0.0275463943743264!GO:0043299;leukocyte degranulation;0.0281016841166521!GO:0051329;interphase of mitotic cell cycle;0.0283607924425357!GO:0008333;endosome to lysosome transport;0.0283771741729599!GO:0051091;positive regulation of transcription factor activity;0.0284411106545432!GO:0002467;germinal center formation;0.0288043353476572!GO:0002824;positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0288043353476572!GO:0002821;positive regulation of adaptive immune response;0.0288043353476572!GO:0051051;negative regulation of transport;0.0295109747899642!GO:0008624;induction of apoptosis by extracellular signals;0.0302992191840758!GO:0051085;chaperone cofactor-dependent protein folding;0.0302992191840758!GO:0006414;translational elongation;0.0304616616022086!GO:0004563;beta-N-acetylhexosaminidase activity;0.0309685484895353!GO:0006351;transcription, DNA-dependent;0.0310492724119396!GO:0002573;myeloid leukocyte differentiation;0.0311360662069144!GO:0019901;protein kinase binding;0.0312091150929355!GO:0002224;toll-like receptor signaling pathway;0.0313921081035332!GO:0002221;pattern recognition receptor signaling pathway;0.0313921081035332!GO:0030118;clathrin coat;0.0316145821933707!GO:0030100;regulation of endocytosis;0.0319204536464464!GO:0030137;COPI-coated vesicle;0.031923305028478!GO:0019752;carboxylic acid metabolic process;0.0322442201170277!GO:0030308;negative regulation of cell growth;0.0323254770307614!GO:0000049;tRNA binding;0.032682971382407!GO:0046467;membrane lipid biosynthetic process;0.0328753767115224!GO:0005905;coated pit;0.0332231892375518!GO:0005788;endoplasmic reticulum lumen;0.0332460643296647!GO:0051235;maintenance of localization;0.0332460643296647!GO:0015036;disulfide oxidoreductase activity;0.0332539035536227!GO:0042611;MHC protein complex;0.0332723104460991!GO:0001776;leukocyte homeostasis;0.0336118453362549!GO:0030031;cell projection biogenesis;0.0339862813730571!GO:0006516;glycoprotein catabolic process;0.0350150079757677!GO:0032774;RNA biosynthetic process;0.0352980759536394!GO:0050727;regulation of inflammatory response;0.0357645488866282!GO:0031347;regulation of defense response;0.0357645488866282!GO:0002718;regulation of cytokine production during immune response;0.0359014603461351!GO:0002367;cytokine production during immune response;0.0359014603461351!GO:0002700;regulation of production of molecular mediator of immune response;0.0359014603461351!GO:0003727;single-stranded RNA binding;0.0359014603461351!GO:0032760;positive regulation of tumor necrosis factor production;0.03674498120432!GO:0051900;regulation of mitochondrial depolarization;0.03674498120432!GO:0045944;positive regulation of transcription from RNA polymerase II promoter;0.036917098283606!GO:0006007;glucose catabolic process;0.037673675266039!GO:0006984;ER-nuclear signaling pathway;0.0381460723574481!GO:0051881;regulation of mitochondrial membrane potential;0.0383311013634951!GO:0006082;organic acid metabolic process;0.038809475804632!GO:0006644;phospholipid metabolic process;0.0388643886765773!GO:0006509;membrane protein ectodomain proteolysis;0.038916051015617!GO:0033619;membrane protein proteolysis;0.038916051015617!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0396222979399138!GO:0016311;dephosphorylation;0.0396288709727066!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0399576288710257!GO:0043407;negative regulation of MAP kinase activity;0.040125166535934!GO:0030984;kininogen binding;0.0401613667098423!GO:0004213;cathepsin B activity;0.0401613667098423!GO:0006595;polyamine metabolic process;0.0403161156042454!GO:0045603;positive regulation of endothelial cell differentiation;0.0410653821482344!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0413027630532267!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0413027630532267!GO:0008312;7S RNA binding;0.041452549332431!GO:0046578;regulation of Ras protein signal transduction;0.0415192913910577!GO:0016049;cell growth;0.0415192913910577!GO:0042092;T-helper 2 type immune response;0.0415243359012645!GO:0035258;steroid hormone receptor binding;0.0415243359012645!GO:0042113;B cell activation;0.0415243359012645!GO:0030374;ligand-dependent nuclear receptor transcription coactivator activity;0.0417131169070357!GO:0005149;interleukin-1 receptor binding;0.0417586937948929!GO:0045746;negative regulation of Notch signaling pathway;0.0417586937948929!GO:0006650;glycerophospholipid metabolic process;0.0418785889613132!GO:0051056;regulation of small GTPase mediated signal transduction;0.042199423977637!GO:0030522;intracellular receptor-mediated signaling pathway;0.0423096620983558!GO:0045920;negative regulation of exocytosis;0.0425561181365283!GO:0043301;negative regulation of leukocyte degranulation;0.0425561181365283!GO:0043305;negative regulation of mast cell degranulation;0.0425561181365283!GO:0005669;transcription factor TFIID complex;0.0425561181365283!GO:0009306;protein secretion;0.0431264926536342!GO:0000278;mitotic cell cycle;0.0437377577668242!GO:0012506;vesicle membrane;0.0437645313561574!GO:0000118;histone deacetylase complex;0.0438804729772164!GO:0031647;regulation of protein stability;0.0441458377482957!GO:0008629;induction of apoptosis by intracellular signals;0.0441458377482957!GO:0033674;positive regulation of kinase activity;0.0444124794031058!GO:0030433;ER-associated protein catabolic process;0.0445867796522526!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0445867796522526!GO:0043071;positive regulation of non-apoptotic programmed cell death;0.0452000621642137!GO:0006914;autophagy;0.0455064098963361!GO:0006376;mRNA splice site selection;0.0455064098963361!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0455064098963361!GO:0003746;translation elongation factor activity;0.0456156163776904!GO:0008154;actin polymerization and/or depolymerization;0.0456987265938307!GO:0051325;interphase;0.0462280763877432!GO:0002697;regulation of immune effector process;0.0464739934555628!GO:0008538;proteasome activator activity;0.0464739934555628!GO:0033033;negative regulation of myeloid cell apoptosis;0.0464739934555628!GO:0001803;regulation of type III hypersensitivity;0.0464739934555628!GO:0032733;positive regulation of interleukin-10 production;0.0464739934555628!GO:0033025;regulation of mast cell apoptosis;0.0464739934555628!GO:0001805;positive regulation of type III hypersensitivity;0.0464739934555628!GO:0033023;mast cell homeostasis;0.0464739934555628!GO:0002431;Fc receptor mediated stimulatory signaling pathway;0.0464739934555628!GO:0033032;regulation of myeloid cell apoptosis;0.0464739934555628!GO:0001802;type III hypersensitivity;0.0464739934555628!GO:0033028;myeloid cell apoptosis;0.0464739934555628!GO:0042590;antigen processing and presentation of exogenous peptide antigen via MHC class I;0.0464739934555628!GO:0033026;negative regulation of mast cell apoptosis;0.0464739934555628!GO:0033024;mast cell apoptosis;0.0464739934555628!GO:0051087;chaperone binding;0.0467006363713237!GO:0007162;negative regulation of cell adhesion;0.0470493008037637!GO:0005815;microtubule organizing center;0.0473129464420128!GO:0001562;response to protozoan;0.0474451324713483!GO:0009299;mRNA transcription;0.0484587235587638!GO:0045309;protein phosphorylated amino acid binding;0.0488221245177696!GO:0000738;DNA catabolic process, exonucleolytic;0.0490068565008075!GO:0042108;positive regulation of cytokine biosynthetic process;0.0490717753312387!GO:0006661;phosphatidylinositol biosynthetic process;0.0490717753312387!GO:0051452;cellular pH reduction;0.0494530994086824!GO:0051453;regulation of cellular pH;0.0494530994086824!GO:0045851;pH reduction;0.0494530994086824 | |||
|sample_id=11879 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue= | |||
|top_motifs=NFE2:3.95286249579;SREBF1,2:3.83448302003;NFE2L2:3.78980147112;FOSL2:3.55196189912;BACH2:3.39890520715;PAX2:3.36841430663;CEBPA,B_DDIT3:3.05577737735;FOS_FOS{B,L1}_JUN{B,D}:2.9852034978;HLF:2.77326054733;SPIB:2.54611411988;SPI1:2.5458834239;ATF5_CREB3:2.40722778889;ATF4:2.28507741119;EP300:2.2809175944;NFE2L1:2.254936677;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:2.22957962368;CREB1:2.20599570433;NFKB1_REL_RELA:2.18379411337;FOXP3:2.16744372319;NANOG{mouse}:2.14991503339;ETS1,2:2.10812048112;ATF6:1.98445812595;FOXN1:1.98043602446;DMAP1_NCOR{1,2}_SMARC:1.77917249547;JUN:1.65950717829;RUNX1..3:1.49412931276;NR1H4:1.47650532311;NFIL3:1.37608496235;HES1:1.35854628799;MAFB:1.30091154883;PAX3,7:1.27606220393;STAT2,4,6:1.18950263271;HSF1,2:1.13457483934;BPTF:1.13261310601;ELF1,2,4:1.00551910219;ATF2:1.0042662376;IRF1,2:1.00045869026;HMX1:0.973765387675;RXRA_VDR{dimer}:0.970053520596;TGIF1:0.927504522713;GLI1..3:0.92284246524;SMAD1..7,9:0.868264757968;PDX1:0.852814734699;FOXD3:0.766739753369;ZBTB16:0.76031389023;IRF7:0.755842471526;ESR1:0.738054758971;NANOG:0.736907423904;TLX2:0.621851602655;HIF1A:0.619530783544;PITX1..3:0.586494797302;TFCP2:0.558938696106;ESRRA:0.519267347442;NFATC1..3:0.513604224728;ALX1:0.503756204117;PAX8:0.379304336009;TBP:0.377784312491;HMGA1,2:0.359449674338;PPARG:0.336533961714;HBP1_HMGB_SSRP1_UBTF:0.302485401199;FOXO1,3,4:0.281863524867;FOXP1:0.246322996408;AHR_ARNT_ARNT2:0.182322447059;EGR1..3:0.148239458934;ALX4:0.140208107989;XBP1:0.110037141494;IKZF2:0.0559135483181;HOX{A5,B5}:0.0470045882197;FOX{F1,F2,J1}:0.0237956296191;MEF2{A,B,C,D}:0.0222549399541;SRF:-0.0169035194609;PRDM1:-0.0292350586324;NR6A1:-0.0299772865649;FOX{D1,D2}:-0.0395131493732;CDX1,2,4:-0.0953543840427;STAT5{A,B}:-0.122304247117;OCT4_SOX2{dimer}:-0.12298074693;MYB:-0.22225463839;GATA4:-0.242942709197;EN1,2:-0.305587989711;FOXL1:-0.316422588316;RFX2..5_RFXANK_RFXAP:-0.32423331176;POU2F1..3:-0.371800839248;MZF1:-0.413089620874;NKX6-1,2:-0.416253009534;STAT1,3:-0.515945146605;PAX1,9:-0.5249461371;SPZ1:-0.534914357381;HOXA9_MEIS1:-0.56020213408;HNF4A_NR2F1,2:-0.597962266275;T:-0.599942450375;RREB1:-0.603678483664;FOXM1:-0.608299008959;RBPJ:-0.629202931174;MYFfamily:-0.66836797284;PAX4:-0.668434338753;VSX1,2:-0.689390523949;PATZ1:-0.696257077234;POU5F1:-0.702390815945;IKZF1:-0.70699618837;SOX2:-0.740049773083;REST:-0.746191146136;NKX3-1:-0.746531738891;RXR{A,B,G}:-0.758020111142;NHLH1,2:-0.808218642182;TFAP4:-0.810366786624;TBX4,5:-0.841024385336;ZNF238:-0.846411013433;ZNF148:-0.867551135146;HNF1A:-0.918342059361;MED-1{core}:-0.924805678073;RORA:-0.93557611074;PRRX1,2:-0.976063517734;GATA6:-0.976866307398;ZFP161:-0.986382379487;GZF1:-1.00423936282;CUX2:-1.01207460753;DBP:-1.0320080845;PAX6:-1.04165994633;MTF1:-1.06325529426;TFAP2B:-1.06376025277;POU6F1:-1.06961438608;ZBTB6:-1.07380658462;RXR{A,B,G}_{NR1H2,PPAR}dimers:-1.09939956554;ZIC1..3:-1.10197819246;MTE{core}:-1.10379828832;NFIX:-1.12220078537;TAL1_TCF{3,4,12}:-1.18511406268;TFAP2{A,C}:-1.20786332909;TOPORS:-1.2190436858;MYOD1:-1.23619465262;NKX2-2,8:-1.2377275054;GCM1,2:-1.24866539484;SP1:-1.26761402586;TFDP1:-1.26866334246;HOX{A6,A7,B6,B7}:-1.31261780455;GTF2A1,2:-1.33645720746;SOX5:-1.35649525741;GTF2I:-1.39111273969;ZNF384:-1.39173425771;SOX{8,9,10}:-1.4372030586;TEAD1:-1.43739169926;UFEwm:-1.45700214999;CRX:-1.45771927999;TLX1..3_NFIC{dimer}:-1.48242795941;ZEB1:-1.5124528782;AIRE:-1.52632755249;HIC1:-1.52878549071;XCPE1{core}:-1.53714952252;ONECUT1,2:-1.54021981981;TP53:-1.54495423059;KLF4:-1.55204100009;RFX1:-1.56204520661;MAZ:-1.56939275571;NKX2-3_NKX2-5:-1.58854656815;MYBL2:-1.58858421317;E2F1..5:-1.58960830704;POU3F1..4:-1.60534745656;BREu{core}:-1.60866170209;ELK1,4_GABP{A,B1}:-1.61783192417;NKX3-2:-1.67981662167;bHLH_family:-1.68207648659;FOXA2:-1.69716120616;NKX2-1,4:-1.69936844659;HOX{A4,D4}:-1.70690858069;NR3C1:-1.713415496;ADNP_IRX_SIX_ZHX:-1.71934171367;TEF:-1.75132120753;LMO2:-1.84796977945;SNAI1..3:-1.86346945346;EVI1:-1.9277762901;EBF1:-1.94361868912;AR:-1.94833456877;POU1F1:-1.95557636567;NR5A1,2:-1.99187063934;FOXQ1:-2.07182291755;PAX5:-2.10432755218;ZNF423:-2.14389694987;SOX17:-2.16834235258;ARID5B:-2.22720475319;NFY{A,B,C}:-2.23416633845;CDC5L:-2.28877504094;GFI1B:-2.33136843416;LHX3,4:-2.4752814735;YY1:-2.52766478961;FOX{I1,J2}:-2.53290572369;NRF1:-2.62892705689;PBX1:-2.76898064878;GFI1:-2.81556569166;HAND1,2:-2.89011028645;ZNF143:-3.12946887939;LEF1_TCF7_TCF7L1,2:-3.37374023792 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11879-125C7;search_select_hide=table117:FF:11879-125C7 | |||
}} | }} |
Latest revision as of 18:26, 4 June 2020
Name: | CD14+ monocytes - treated with B-glucan, donor2 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13489 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13489
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13489
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.101 |
10 | 10 | 0.0212 |
100 | 100 | 0.773 |
101 | 101 | 0.871 |
102 | 102 | 0.604 |
103 | 103 | 0.386 |
104 | 104 | 0.604 |
105 | 105 | 0.145 |
106 | 106 | 3.19758e-4 |
107 | 107 | 0.244 |
108 | 108 | 0.969 |
109 | 109 | 0.315 |
11 | 11 | 0.191 |
110 | 110 | 0.255 |
111 | 111 | 0.0358 |
112 | 112 | 0.319 |
113 | 113 | 0.421 |
114 | 114 | 0.0193 |
115 | 115 | 0.25 |
116 | 116 | 0.944 |
117 | 117 | 0.0667 |
118 | 118 | 0.193 |
119 | 119 | 0.106 |
12 | 12 | 0.352 |
120 | 120 | 0.682 |
121 | 121 | 0.474 |
122 | 122 | 0.644 |
123 | 123 | 0.0871 |
124 | 124 | 0.455 |
125 | 125 | 0.436 |
126 | 126 | 0.284 |
127 | 127 | 0.458 |
128 | 128 | 0.031 |
129 | 129 | 0.507 |
13 | 13 | 0.153 |
130 | 130 | 0.128 |
131 | 131 | 0.805 |
132 | 132 | 0.0547 |
133 | 133 | 0.704 |
134 | 134 | 0.726 |
135 | 135 | 0.759 |
136 | 136 | 0.984 |
137 | 137 | 0.0138 |
138 | 138 | 0.289 |
139 | 139 | 0.0337 |
14 | 14 | 0.511 |
140 | 140 | 0.159 |
141 | 141 | 0.346 |
142 | 142 | 0.2 |
143 | 143 | 0.0304 |
144 | 144 | 0.602 |
145 | 145 | 0.521 |
146 | 146 | 0.479 |
147 | 147 | 0.462 |
148 | 148 | 0.0112 |
149 | 149 | 0.81 |
15 | 15 | 0.159 |
150 | 150 | 0.465 |
151 | 151 | 0.384 |
152 | 152 | 0.122 |
153 | 153 | 0.416 |
154 | 154 | 0.495 |
155 | 155 | 0.671 |
156 | 156 | 0.577 |
157 | 157 | 0.293 |
158 | 158 | 0.0132 |
159 | 159 | 0.818 |
16 | 16 | 0.352 |
160 | 160 | 0.428 |
161 | 161 | 0.549 |
162 | 162 | 0.248 |
163 | 163 | 0.144 |
164 | 164 | 0.0971 |
165 | 165 | 0.23 |
166 | 166 | 0.466 |
167 | 167 | 0.142 |
168 | 168 | 0.365 |
169 | 169 | 0.0091 |
17 | 17 | 0.224 |
18 | 18 | 0.119 |
19 | 19 | 0.424 |
2 | 2 | 0.813 |
20 | 20 | 0.261 |
21 | 21 | 0.432 |
22 | 22 | 0.233 |
23 | 23 | 0.0473 |
24 | 24 | 0.342 |
25 | 25 | 0.413 |
26 | 26 | 0.054 |
27 | 27 | 0.718 |
28 | 28 | 0.434 |
29 | 29 | 0.359 |
3 | 3 | 0.139 |
30 | 30 | 0.495 |
31 | 31 | 0.779 |
32 | 32 | 0.721 |
33 | 33 | 0.475 |
34 | 34 | 0.583 |
35 | 35 | 0.163 |
36 | 36 | 0.161 |
37 | 37 | 0.0606 |
38 | 38 | 0.377 |
39 | 39 | 0.796 |
4 | 4 | 0.938 |
40 | 40 | 0.182 |
41 | 41 | 0.00974 |
42 | 42 | 0.428 |
43 | 43 | 0.0287 |
44 | 44 | 0.941 |
45 | 45 | 0.679 |
46 | 46 | 0.18 |
47 | 47 | 0.638 |
48 | 48 | 0.589 |
49 | 49 | 0.0994 |
5 | 5 | 0.314 |
50 | 50 | 0.945 |
51 | 51 | 0.463 |
52 | 52 | 0.33 |
53 | 53 | 0.383 |
54 | 54 | 0.39 |
55 | 55 | 0.553 |
56 | 56 | 0.685 |
57 | 57 | 0.77 |
58 | 58 | 0.144 |
59 | 59 | 0.188 |
6 | 6 | 0.657 |
60 | 60 | 0.0539 |
61 | 61 | 0.642 |
62 | 62 | 0.0732 |
63 | 63 | 0.534 |
64 | 64 | 0.414 |
65 | 65 | 0.217 |
66 | 66 | 0.301 |
67 | 67 | 0.56 |
68 | 68 | 0.827 |
69 | 69 | 0.831 |
7 | 7 | 0.294 |
70 | 70 | 0.0283 |
71 | 71 | 0.0335 |
72 | 72 | 0.287 |
73 | 73 | 0.109 |
74 | 74 | 0.227 |
75 | 75 | 0.12 |
76 | 76 | 0.163 |
77 | 77 | 0.507 |
78 | 78 | 0.0835 |
79 | 79 | 0.559 |
8 | 8 | 0.44 |
80 | 80 | 0.327 |
81 | 81 | 0.354 |
82 | 82 | 0.157 |
83 | 83 | 0.0245 |
84 | 84 | 0.205 |
85 | 85 | 0.011 |
86 | 86 | 0.0305 |
87 | 87 | 0.633 |
88 | 88 | 0.657 |
89 | 89 | 0.249 |
9 | 9 | 0.435 |
90 | 90 | 0.111 |
91 | 91 | 0.256 |
92 | 92 | 0.187 |
93 | 93 | 0.277 |
94 | 94 | 0.0556 |
95 | 95 | 0.457 |
96 | 96 | 0.361 |
97 | 97 | 0.799 |
98 | 98 | 0.126 |
99 | 99 | 0.0565 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13489
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0011102 human CD14-positive monocytes - treated with B-glucan sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000766 (myeloid leukocyte)
0000219 (motile cell)
0000325 (stuff accumulating cell)
0000473 (defensive cell)
0000234 (phagocyte)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0000255 (eukaryotic cell)
0000576 (monocyte)
0000860 (classical monocyte)
0002057 (CD14-positive, CD16-negative classical monocyte)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
0000625 (experimental infection sample)
0000350 (experimentally modified sample)
0000630 (beta-glucan treatment sample)
0011102 (human CD14-positive monocytes - treated with B-glucan sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)
CL:0002057 (CD14-positive, CD16-negative classical monocyte)