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MCL coexpression mm9:1271: Difference between revisions

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{{MCL_coexpression_mm9
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nucleoside transmembrane transporter activity;0.00451955733015958;269346!GO:0005415;nucleoside:sodium symporter activity;0.00451955733015958;269346!GO:0001882;nucleoside binding;0.00451955733015958;269346!GO:0015860;purine nucleoside transport;0.00451955733015958;269346!GO:0015858;nucleoside transport;0.00723049934476794;269346!GO:0005337;nucleoside transmembrane transporter activity;0.009036638597603;269346!GO:0015932;nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity;0.009036638597603;269346!GO:0015370;solute:sodium symporter activity;0.0451015396334998;269346!GO:0015294;solute:cation symporter activity;0.0495709027396678;269346!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid 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|gostat_on_MCL_coexpression=GO:0015211;purine nucleoside transmembrane transporter activity;0.00451955733015958;269346!GO:0005415;nucleoside:sodium symporter activity;0.00451955733015958;269346!GO:0001882;nucleoside binding;0.00451955733015958;269346!GO:0015860;purine nucleoside transport;0.00451955733015958;269346!GO:0015858;nucleoside transport;0.00723049934476794;269346!GO:0005337;nucleoside transmembrane transporter activity;0.009036638597603;269346!GO:0015932;nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity;0.009036638597603;269346!GO:0015370;solute:sodium symporter activity;0.0451015396334998;269346!GO:0015294;solute:cation symporter activity;0.0495709027396678;269346!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;0.0495709027396678;269346!
|ontology_enrichment_celltype=CL:0000838!1.76e-10!12;CL:0000084!1.70e-09!11;CL:0000827!1.70e-09!11;CL:0000988!2.21e-09!32;CL:0002032!2.21e-09!32;CL:0000037!2.21e-09!32;CL:0000566!2.21e-09!32;CL:0000837!2.21e-09!32;CL:0000542!2.51e-09!13;CL:0000051!2.51e-09!13;CL:0002031!3.24e-09!25;CL:0000791!4.52e-08!9;CL:0000789!4.52e-08!9;CL:0002420!4.52e-08!9;CL:0002419!4.52e-08!9;CL:0000790!4.52e-08!9;CL:0000624!4.36e-07!8;CL:0002242!8.87e-07!16
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0002193!3.50e-18!48;UBERON:0002405!3.50e-18!48;UBERON:0004177!8.68e-18!29;UBERON:0005057!8.68e-18!29;UBERON:0002390!4.93e-16!45;UBERON:0003061!4.93e-16!45;UBERON:0000077!3.66e-14!35;UBERON:0003408!5.91e-14!24;UBERON:0006562!6.01e-14!24;UBERON:0001557!6.01e-14!24;UBERON:0001042!6.01e-14!24;UBERON:0008814!6.01e-14!24;UBERON:0009145!6.01e-14!24;UBERON:0002370!2.05e-13!23;UBERON:0000974!2.05e-13!23;UBERON:0004807!2.05e-13!23;UBERON:0005058!2.05e-13!23;UBERON:0003351!2.05e-13!23;UBERON:0009113!2.05e-13!23;UBERON:0003295!2.05e-13!23;UBERON:0009722!2.05e-13!23;UBERON:0005562!2.05e-13!23;UBERON:0007690!2.05e-13!23;UBERON:0001004!9.14e-12!42;UBERON:0000072!1.80e-11!27;UBERON:0000065!2.91e-11!41;UBERON:0001041!1.22e-09!80;UBERON:0007811!7.68e-09!36;UBERON:0001007!3.26e-08!116;UBERON:0001555!3.26e-08!116;UBERON:0007026!3.26e-08!116;UBERON:0000063!5.19e-08!35;UBERON:0004119!8.48e-08!118;UBERON:0000925!8.48e-08!118;UBERON:0006595!8.48e-08!118;UBERON:0003081!9.42e-08!87;UBERON:0004921!1.92e-07!114
}}

Latest revision as of 16:39, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr11:109294025..109294044,+p8@Amz2
Mm9::chr12:85559762..85559778,-p5@C130039O16Rik
Mm9::chr18:56629179..56629195,+p@chr18:56629179..56629195
+
Mm9::chr19:12873114..12873126,+p2@Lpxn
Mm9::chr2:122252168..122252197,+p1@Slc28a2
Mm9::chr9:103391679..103391706,-p@chr9:103391679..103391706
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0015211purine nucleoside transmembrane transporter activity0.00451955733015958
GO:0005415nucleoside:sodium symporter activity0.00451955733015958
GO:0001882nucleoside binding0.00451955733015958
GO:0015860purine nucleoside transport0.00451955733015958
GO:0015858nucleoside transport0.00723049934476794
GO:0005337nucleoside transmembrane transporter activity0.009036638597603
GO:0015932nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity0.009036638597603
GO:0015370solute:sodium symporter activity0.0451015396334998
GO:0015294solute:cation symporter activity0.0495709027396678
GO:0015931nucleobase, nucleoside, nucleotide and nucleic acid transport0.0495709027396678



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
hemolymphoid system3.50e-1848
immune system3.50e-1848
hemopoietic organ8.68e-1829
immune organ8.68e-1829
hematopoietic system4.93e-1645
blood island4.93e-1645
mixed endoderm/mesoderm-derived structure3.66e-1435
gland of gut5.91e-1424
pharynx6.01e-1424
upper respiratory tract6.01e-1424
chordate pharynx6.01e-1424
pharyngeal arch system6.01e-1424
pharyngeal region of foregut6.01e-1424
thymus2.05e-1323
neck2.05e-1323
respiratory system epithelium2.05e-1323
hemolymphoid system gland2.05e-1323
pharyngeal epithelium2.05e-1323
thymic region2.05e-1323
pharyngeal gland2.05e-1323
entire pharyngeal arch endoderm2.05e-1323
thymus primordium2.05e-1323
early pharyngeal endoderm2.05e-1323
respiratory system9.14e-1242
segment of respiratory tract1.80e-1127
respiratory tract2.91e-1141
foregut1.22e-0980
craniocervical region7.68e-0936
digestive system3.26e-08116
digestive tract3.26e-08116
primitive gut3.26e-08116
organ segment5.19e-0835
endoderm-derived structure8.48e-08118
endoderm8.48e-08118
presumptive endoderm8.48e-08118
lateral plate mesoderm9.42e-0887
subdivision of digestive tract1.92e-07114


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.135108
MA0004.10.536396
MA0006.10.359699
MA0007.10.52077
MA0009.10.987341
MA0014.10.0315641
MA0017.10.387481
MA0019.10.800946
MA0024.10.942716
MA0025.11.22395
MA0027.12.64231
MA0028.10.370592
MA0029.10.920529
MA0030.10.927235
MA0031.10.890871
MA0038.10.686534
MA0040.11.00009
MA0041.12.01886
MA0042.11.12834
MA0043.11.08567
MA0046.11.02391
MA0048.10.943003
MA0050.10.57678
MA0051.10.695779
MA0052.11.00829
MA0055.11.71525
MA0056.10
MA0057.10.149949
MA0058.10.436487
MA0059.10.449345
MA0060.10.275911
MA0061.10.307097
MA0063.10
MA0066.10.675169
MA0067.11.33603
MA0068.10.467569
MA0069.11.00864
MA0070.10.998765
MA0071.10.575909
MA0072.10.990133
MA0073.10.00638767
MA0074.10.638014
MA0076.10.407465
MA0077.10.968053
MA0078.10.729877
MA0081.10.473489
MA0083.11.08487
MA0084.11.66561
MA0087.11.04109
MA0088.10.111145
MA0089.10
MA0090.10.500693
MA0091.10.55008
MA0092.10.501022
MA0093.10.379257
MA0095.10
MA0098.10
MA0100.10.626021
MA0101.10.458688
MA0103.11.03097
MA0105.10.199622
MA0106.10.737893
MA0107.10.392331
MA0108.20.824407
MA0109.10
MA0111.10.515457
MA0113.10.708789
MA0114.10.304661
MA0115.11.08851
MA0116.10.359483
MA0117.11.05576
MA0119.10.459301
MA0122.11.07591
MA0124.11.28237
MA0125.11.20757
MA0130.10
MA0131.10.796279
MA0132.10
MA0133.10
MA0135.11.1226
MA0136.12.67613
MA0139.10.243463
MA0140.10.625902
MA0141.10.419361
MA0142.10.876028
MA0143.10.725672
MA0144.10.307873
MA0145.10.119202
MA0146.10.153598
MA0147.10.320675
MA0148.10.553294
MA0149.10.464445
MA0062.20.591842
MA0035.20.630778
MA0039.20.0271858
MA0138.20.788113
MA0002.20.689262
MA0137.20.416331
MA0104.20.261255
MA0047.20.685741
MA0112.20.76177
MA0065.20.763394
MA0150.10.520653
MA0151.10
MA0152.10.685852
MA0153.11.13945
MA0154.10.933846
MA0155.10.822245
MA0156.12.76344
MA0157.10.843181
MA0158.10
MA0159.10.881902
MA0160.10.556423
MA0161.10
MA0162.10.0465447
MA0163.10.163321
MA0164.10.658997
MA0080.22.70103
MA0018.20.669032
MA0099.20.781628
MA0079.20.0520572
MA0102.21.7182
MA0258.11.4396
MA0259.10.309517
MA0442.10