FF:11870-125B7: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00004743 | ||
| | |accession_numbers=CAGE;DRX008139;DRR009011;DRZ000436;DRZ001821;DRZ011786;DRZ013171 | ||
| | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000766,CL:0000219,CL:0000325,CL:0000473,CL:0000234,CL:0000738,CL:0002087,CL:0000255,CL:0000576,CL:0000860,CL:0002057 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001,FF:0000625,FF:0000350,FF:0000628,FF:0011103 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr2:68592406..68592424,+!p1@PLEK!3.57!3718.43!PLEK;;chr16:85932760..85932775,+!p1@IRF8!3.09!1235.21!IRF8;;chr11:47400078..47400106,-!p1@SPI1!2.72!527.95!SPI1;;chr10:64576105..64576133,-!p1@EGR2!2.63!842.00!EGR2;;chr10:35484053..35484076,+!p1@CREM!2.55!849.43!CREM;;chr12:54778471..54778528,-!p1@ZNF385A!2.50!317.38!ZNF385A;;chr7:115670804..115670825,-!p1@TFEC!2.43!266.92!TFEC;;chr11:47399947..47399961,-!p3@SPI1!2.26!181.62!SPI1;;chr11:64764435..64764449,-!p1@BATF2!2.18!202.37!BATF2;;chr7:128577972..128578047,+!p1@IRF5!2.15!217.74!IRF5;;chr6:36355431..36355466,-!p1@ETV7!2.12!130.39!ETV7;;chr6:106534192..106534224,+!p1@PRDM1!2.11!346.33!PRDM1;;chr11:47400062..47400077,-!p2@SPI1!2.06!115.02!SPI1;;chr21:34442439..34442455,+!p1@OLIG1!2.05!110.15!OLIG1;;chr2:70142232..70142251,+!p1@MXD1!2.02!555.10!MXD1;;chr17:45810594..45810608,+!p1@TBX21!1.98!93.50!TBX21;;chr5:131826457..131826514,-!p1@IRF1!1.97!3358.78!IRF1;;chr20:39317868..39317884,-!p1@MAFB!1.97!1029.77!MAFB;;chr1:25256756..25256774,-!p1@RUNX3!1.96!165.74!RUNX3;;chr21:36260295..36260310,-!p3@RUNX1!1.93!131.41!RUNX1;;chr11:47399996..47400014,-!p4@SPI1!1.89!76.08!SPI1;;chr11:615942..615957,-!p1@IRF7!1.86!640.40!IRF7;;chr11:65430554..65430579,-!p3@RELA!1.84!168.81!RELA;;chr6:106534230..106534254,+!p2@PRDM1!1.84!163.69!PRDM1;;chr2:68592394..68592405,+!p2@PLEK!1.83!66.60!PLEK;;chr16:31885093..31885165,+!p1@ZNF267!1.80!894.00!ZNF267;;chr10:64018918..64018936,+!p2@ZNF365!1.80!62.25!ZNF365;;chr10:35484090..35484104,+!p6@CREM!1.79!60.97!CREM;;chr11:47400032..47400043,-!p5@SPI1!1.79!60.20!SPI1;;chr11:65430535..65430549,-!p4@RELA!1.78!67.88!RELA;;chr1:221052776..221052799,+!p1@HLX!1.77!100.67!HLX;;chr16:79634624..79634642,-!p1@MAF!1.76!210.56!MAF;;chr14:35872453..35872485,-!p2@NFKBIA!1.75!131.41!NFKBIA;;chr2:231084639..231084654,-!p2@SP110!1.73!85.30!SP110;;chr10:31288398..31288455,-!p2@ZNF438!1.73!60.71!ZNF438;;chr19:33793430..33793447,-!p1@CEBPA!1.72!205.70!CEBPA;;chr1:212782094..212782109,+!p1@ATF3!1.71!1287.72!ATF3;;chr22:38597987..38598021,+!p2@MAFF!1.70!285.88!MAFF;;chr12:54778351..54778378,-!p6@ZNF385A!1.70!49.18!ZNF385A;;chr19:45971246..45971265,+!p1@FOSB!1.69!844.05!FOSB;;chr2:97202480..97202499,+!p1@ARID5A!1.69!456.48!ARID5A;;chr19:50432132..50432217,+!p2@ATF5!1.69!57.12!ATF5;;chr14:75988831..75988847,+!p2@BATF!1.68!46.88!BATF;;chr12:72056749..72056767,+!p6@THAP2!1.66!49.18!THAP2;;chr6:391743..391759,+!p1@IRF4!1.66!44.57!IRF4;;chr14:75988771..75988826,+!p1@BATF!1.65!57.12!BATF;;chrX:153305787..153305807,-!p3@MECP2!1.63!41.75!MECP2;;chr2:145277640..145277771,-!p1@ZEB2!1.61!501.56!ZEB2;;chr2:145275162..145275202,-!p2@ZEB2!1.61!225.93!ZEB2;;chr21:36421535..36421610,-!p2@RUNX1!1.58!128.08!RUNX1;;chr21:30671690..30671762,+!p2@BACH1!1.58!122.44!BACH1;;chr14:35873947..35873965,-!p1@NFKBIA!1.57!2161.48!NFKBIA;;chr19:36391434..36391450,-!p1@NFKBID!1.57!68.91!NFKBID;;chr2:157189180..157189290,-!p1@NR4A2!1.56!176.24!NR4A2;;chr1:158979872..158979898,+!p3@IFI16!1.55!103.49!IFI16;;chr1:158985493..158985535,+!p4@IFI16!1.55!52.26!IFI16;;chr10:31288370..31288393,-!p3@ZNF438!1.55!34.84!ZNF438;;chr10:51572408..51572454,+!p3@NCOA4!1.54!189.05!NCOA4;;chr8:22550982..22550999,-!p1@EGR3!1.54!91.45!EGR3;;chr12:72056800..72056834,+!p1@THAP2!1.53!43.80!THAP2;;chr11:615570..615721,-!p2@IRF7!1.52!62.25!IRF7;;chr6:144385698..144385742,-!p2@PLAGL1!1.52!38.94!PLAGL1;;chr21:30671235..30671253,+!p1@BACH1!1.51!383.22!BACH1;;chr16:79634595..79634620,-!p2@MAF!1.51!56.36!MAF;;chr1:221052733..221052749,+!p2@HLX!1.51!39.96!HLX;;chr11:47400045..47400060,-!p6@SPI1!1.51!31.51!SPI1;;chr12:48298765..48298783,-!p2@VDR!1.50!62.25!VDR;;chrX:129244454..129244488,-!p1@ELF4!1.49!209.54!ELF4;;chr10:51572339..51572376,+!p4@NCOA4!1.49!66.09!NCOA4;;chr10:35484804..35484902,+!p2@CREM!1.48!108.87!CREM;;chr12:72056773..72056796,+!p3@THAP2!1.48!37.40!THAP2;;chr3:12329397..12329433,+!p2@PPARG!1.47!63.78!PPARG;;chr21:34398234..34398250,+!p1@OLIG2!1.47!28.18!OLIG2;;chr4:103422499..103422632,+!p1@NFKB1!1.46!560.22!NFKB1;;chr7:50344289..50344323,+!p1@IKZF1!1.46!27.92!IKZF1;;chr4:185395590..185395627,-!p3@IRF2!1.45!33.30!IRF2;;chr7:150946376..150946389,-!p6@SMARCD3!1.44!26.38!SMARCD3;;chr19:45251395..45251432,+!p8@BCL3!1.43!25.62!BCL3;;chr12:11802753..11802834,+!p2@ETV6!1.42!120.40!ETV6;;chr9:110250697..110250738,-!p2@KLF4!1.41!28.95!KLF4;;chr9:110252035..110252057,-!p1@KLF4!1.40!368.87!KLF4;;chr22:38598086..38598105,+!p1@MAFF!1.40!250.01!MAFF;;chr21:36260343..36260402,-!p6@RUNX1!1.40!37.91!RUNX1;;chr2:231090471..231090504,+!p2@SP140!1.40!24.34!SP140;;chr12:56415246..56415286,+!p2@IKZF4!1.40!24.08!IKZF4;;chr6:106535598..106535637,+!p7@PRDM1!1.39!23.82!PRDM1;;chr1:25256439..25256476,-!p3@RUNX3!1.39!23.31!RUNX3;;chr10:104155480..104155534,+!p2@NFKB2!1.38!145.76!NFKB2;;chr11:47399920..47399931,-!p7@SPI1!1.38!22.80!SPI1;;chr20:48599506..48599526,+!p1@SNAI1!1.37!138.58!SNAI1;;chr9:102584159..102584174,+!p2@NR4A3!1.37!40.22!NR4A3;;chr4:185395633..185395651,-!p2@IRF2!1.37!35.61!IRF2;;chr3:39195037..39195069,-!p2@CSRNP1!1.36!132.18!CSRNP1;;chr17:38497662..38497713,+!p4@RARA!1.36!25.10!RARA;;chr13:41593425..41593480,-!p1@ELF1!1.35!133.46!ELF1;;chr14:35872962..35873025,-!p3@NFKBIA!1.35!53.03!NFKBIA;;chr2:61108695..61108753,+!p1@REL!1.34!138.07!REL;;chr18:3449720..3449749,+!p2@TGIF1!1.34!44.06!TGIF1;;chr21:36260325..36260341,-!p14@RUNX1!1.34!21.01!RUNX1;;chr20:48807351..48807384,+!p1@CEBPB!1.33!2004.97!CEBPB;;chr19:45252008..45252024,+!p2@BCL3!1.33!65.32!BCL3;;chr4:106068026..106068084,+!p1@TET2!1.31!168.30!TET2;;chrX:129244430..129244442,-!p5@ELF4!1.31!19.21!ELF4;;chr10:104154246..104154347,+!p3@NFKB2!1.29!109.64!NFKB2;;chr3:187463179..187463201,-!p2@BCL6!1.29!74.54!BCL6;;chr8:116681123..116681143,-!p4@TRPS1!1.29!35.09!TRPS1;;chr3:126191157..126191171,-!p4@ZXDC!1.29!18.70!ZXDC;;chr9:129567282..129567353,+!p1@ZBTB43!1.28!229.52!ZBTB43;;chr2:191885737..191885750,-!p4@STAT1!1.28!18.19!STAT1;;chr19:45250948..45250998,+!p3@BCL3!1.27!44.06!BCL3;;chr16:89787973..89788001,+!p3@ZNF276!1.27!33.56!ZNF276;;chr9:102584128..102584144,+!p3@NR4A3!1.27!33.56!NR4A3;;chr3:39195139..39195150,-!p3@CSRNP1!1.27!22.54!CSRNP1;;chr12:48298785..48298828,-!p1@VDR!1.26!88.89!VDR;;chr19:19496539..19496576,+!p8@GATAD2A!1.26!29.97!GATAD2A;;chr6:44233252..44233296,-!p1@NFKBIE!1.25!161.89!NFKBIE;;chr21:36260980..36261011,-!p1@RUNX1!1.24!462.37!RUNX1;;chr2:231084820..231084836,-!p5@SP110!1.24!18.96!SP110;;chr16:79634581..79634592,-!p4@MAF!1.24!16.39!MAF;;chr1:37940170..37940190,+!p1@ZC3H12A!1.23!191.10!ZC3H12A;;chr7:17338266..17338282,+!p1@AHR!1.23!168.04!AHR;;chr2:145277882..145277967,-!p3@ZEB2!1.23!27.67!ZEB2;;chr18:3449618..3449634,+!p13@TGIF1!1.23!19.98!TGIF1;;chr1:158979922..158979933,+!p13@IFI16!1.23!16.14!IFI16;;chr2:231090433..231090469,+!p1@SP140!1.23!16.14!SP140;;chr1:221054922..221054933,+!p16@HLX!1.23!15.88!HLX;;chr21:30672433..30672464,+!p6@BACH1!1.23!15.88!BACH1;;chr12:52445218..52445237,+!p1@NR4A1!1.22!193.66!NR4A1;;chr6:15246200..15246214,+!p2@JARID2!1.22!42.78!JARID2;;chr2:70314240..70314256,+!p4@PCBP1!1.22!32.28!PCBP1;;chr10:64576035..64576046,-!p2@EGR2!1.21!15.37!EGR2;;chr10:3827371..3827386,-!p2@KLF6!1.20!122.96!KLF6;;chr6:126240380..126240430,+!p2@NCOA7!1.20!38.68!NCOA7;;chr22:38598057..38598071,+!p3@MAFF!1.20!34.84!MAFF;;chr16:3285119..3285133,-!p2@ZNF200!1.20!29.46!ZNF200;;chr7:149470641..149470694,-!p1@ZNF467!1.19!64.81!ZNF467;;chr5:71803177..71803255,-!p1@ZNF366!1.19!14.60!ZNF366;;chr21:30672734..30672748,+!p11@BACH1!1.19!14.34!BACH1;;chr3:101568349..101568365,+!p1@NFKBIZ!1.18!730.83!NFKBIZ;;chr18:3449586..3449617,+!p8@TGIF1!1.18!22.54!TGIF1;;chr6:126240442..126240459,+!p4@NCOA7!1.18!17.93!NCOA7;;chr7:28725740..28725778,+!p1@CREB5!1.17!121.93!CREB5;;chr1:38325227..38325246,-!p2@MTF1!1.17!18.96!MTF1;;chr6:126240463..126240489,+!p6@NCOA7!1.17!15.37!NCOA7;;chr21:40177845..40177863,+!p1@ETS2!1.16!783.85!ETS2;;chr6:12012170..12012245,+!p1@HIVEP1!1.16!67.88!HIVEP1;;chr17:79885537..79885554,-!p2@MAFG!1.16!25.62!MAFG;;chr2:70167296..70167306,+!p3@MXD1!1.16!20.75!MXD1;;chr14:35872926..35872951,-!p4@NFKBIA!1.16!19.21!NFKBIA;;chr14:35872494..35872511,-!p5@NFKBIA!1.16!17.93!NFKBIA;;chr3:187455634..187455651,-!p7@BCL6!1.16!13.58!BCL6;;chr1:158979792..158979814,+!p2@IFI16!1.15!125.77!IFI16;;chr5:142782823..142782854,-!p3@NR3C1!1.15!18.70!NR3C1;;chr1:221052994..221053008,+!p6@HLX!1.15!15.63!HLX;;chr2:231084659..231084721,-!p1@SP110!1.14!298.17!SP110;;chr10:104155455..104155479,+!p1@NFKB2!1.14!185.20!NFKB2;;chr3:150126101..150126118,+!p6@TSC22D2!1.14!20.75!TSC22D2;;chr1:221052840..221052875,+!p4@HLX!1.14!15.37!HLX;;chr3:187455680..187455700,-!p4@BCL6!1.14!12.81!BCL6;;chrX:153305741..153305753,-!p4@MECP2!1.14!12.81!MECP2;;chr8:71316428..71316459,-!p2@NCOA2!1.13!21.01!NCOA2;;chr2:238600998..238601013,+!p5@LRRFIP1!1.13!12.55!LRRFIP1;;chr1:8484007..8484061,-!p13@RERE!1.12!15.63!RERE;;chr10:64575812..64575824,-!p4@EGR2!1.12!12.30!EGR2;;chr17:38497715..38497734,+!p8@RARA!1.12!12.30!RARA;;chr17:38474489..38474548,+!p1@RARA!1.11!375.79!RARA;;chr1:221053049..221053075,+!p3@HLX!1.11!20.75!HLX;;chr2:192015701..192015743,-!p1@STAT4!1.11!16.39!STAT4;;chr3:12330560..12330579,+!p1@PPARG!1.11!13.58!PPARG;;chr3:39195075..39195088,-!p1@CSRNP1!1.10!73.26!CSRNP1;;chr19:42636586..42636607,-!p1@POU2F2!1.10!32.02!POU2F2;;chr20:48807456..48807475,+!p3@CEBPB!1.10!22.54!CEBPB;;chr12:11802690..11802704,+!p4@ETV6!1.10!16.65!ETV6;;chr7:115670792..115670797,-!p2@TFEC!1.10!11.53!TFEC;;chr19:54058073..54058088,+!p1@ZNF331!1.10!11.53!ZNF331;;chr3:170075436..170075520,+!p1@SKIL!1.09!243.10!SKIL;;chr2:238600933..238600985,+!p3@LRRFIP1!1.09!60.97!LRRFIP1;;chr18:3448455..3448480,+!p5@TGIF1!1.09!20.75!TGIF1;;chr2:145271342..145271377,-!p5@ZEB2!1.09!11.27!ZEB2;;chr2:70142189..70142223,+!p2@MXD1!1.08!79.41!MXD1;;chr9:102584262..102584276,+!p1@NR4A3!1.08!24.59!NR4A3;;chr9:3526360..3526421,-!p5@RFX3!1.08!20.49!RFX3;;chr12:54785074..54785122,-!p2@ZNF385A!1.08!17.16!ZNF385A;;chr4:185395191..185395226,-!p4@IRF2!1.08!15.63!IRF2;;chr3:107318229..107318239,+!p17@BBX!1.08!11.01!BB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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000222;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000234;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000576;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000763;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000766;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000860;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002193;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002390;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002405 | |||
|ffid_belonging_in_development=CL:0000049,CL:0000134,CL:0002057 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 41: | ||
|fonse_treatment=FF:0000625,FF:0000628,FF:0011103,FF:11870-125B7 | |fonse_treatment=FF:0000625,FF:0000628,FF:0011103,FF:11870-125B7 | ||
|fonse_treatment_closure=FF:0000625,FF:0000628,FF:0011103,FF:11870-125B7 | |fonse_treatment_closure=FF:0000625,FF:0000628,FF:0011103,FF:11870-125B7 | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520BCG%252c%2520donor2.CNhs13475.11870-125B7.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520BCG%252c%2520donor2.CNhs13475.11870-125B7.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520BCG%252c%2520donor2.CNhs13475.11870-125B7.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520BCG%252c%2520donor2.CNhs13475.11870-125B7.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520BCG%252c%2520donor2.CNhs13475.11870-125B7.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11870-125B7 | |||
|is_a=EFO:0002091;;FF:0011103 | |||
|is_obsolete= | |||
|library_id=CNhs13475 | |||
|library_id_phase_based=2:CNhs13475 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11870 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11870 | |||
|name=CD14+ monocytes - treated with BCG, donor2 | |||
|namespace= | |namespace= | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs13475,LSID1024,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
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| |||
|rna_box=125 | |||
|rna_catalog_number= | |||
|rna_concentration=0.63375 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number=D4-1 | |||
|rna_od260/230=1.68 | |||
|rna_od260/280=2.03 | |||
|rna_position=B7 | |||
|rna_rin=8.8 | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=125B7 | |||
|rna_weight_ug=2.851875 | |||
|sample_age=51 | |||
|sample_category=primary cells | |||
|sample_cell_catalog= | |||
|sample_cell_line= | |||
|sample_cell_lot= | |||
|sample_cell_type=monocyte | |||
|sample_collaboration=Christine Wells (University of Queensland) | |||
|sample_company= | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease= | |||
|sample_donor(cell lot)=donor2 | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.46726188021841e-273!GO:0005737;cytoplasm;1.42971329184933e-129!GO:0043227;membrane-bound organelle;4.86797315347333e-113!GO:0043231;intracellular membrane-bound organelle;8.91961836019432e-113!GO:0043226;organelle;3.1669746260863e-105!GO:0043229;intracellular organelle;1.79830599163894e-104!GO:0044444;cytoplasmic part;2.12331205462343e-83!GO:0005515;protein binding;3.54676734286247e-72!GO:0044422;organelle part;1.54038693710601e-69!GO:0044446;intracellular organelle part;5.19113954509477e-68!GO:0044237;cellular metabolic process;1.90330766917894e-65!GO:0044238;primary metabolic process;2.1286770806361e-64!GO:0043170;macromolecule metabolic process;4.95045310658122e-62!GO:0032991;macromolecular complex;6.03539685073843e-57!GO:0003723;RNA binding;8.41143475600439e-56!GO:0030529;ribonucleoprotein complex;2.64960488016482e-50!GO:0019538;protein metabolic process;7.63558256370915e-49!GO:0044267;cellular protein metabolic process;1.18569406313212e-45!GO:0044260;cellular macromolecule metabolic process;1.81693432478135e-45!GO:0044428;nuclear part;1.89505330607377e-45!GO:0005634;nucleus;1.63341926200373e-44!GO:0033036;macromolecule localization;5.3671300953026e-42!GO:0015031;protein transport;4.40852778590403e-41!GO:0045184;establishment of protein localization;4.63271709114508e-41!GO:0006412;translation;6.82981699156305e-41!GO:0008104;protein localization;1.97010628057839e-39!GO:0043233;organelle lumen;9.63006078897916e-37!GO:0031974;membrane-enclosed lumen;9.63006078897916e-37!GO:0005829;cytosol;3.15361660175562e-35!GO:0031090;organelle membrane;6.27851802344102e-34!GO:0043283;biopolymer metabolic process;1.69144043563852e-32!GO:0006915;apoptosis;3.53401882564879e-32!GO:0012501;programmed cell death;3.88292191481007e-32!GO:0010467;gene expression;3.86450912554457e-31!GO:0008219;cell death;1.1090407263035e-30!GO:0016265;death;1.1090407263035e-30!GO:0009059;macromolecule biosynthetic process;2.7048317776674e-30!GO:0006396;RNA processing;4.88710325013428e-30!GO:0016071;mRNA metabolic process;5.51562189744265e-30!GO:0043234;protein complex;1.38165249496105e-28!GO:0016043;cellular component organization and biogenesis;1.47426887355742e-28!GO:0009058;biosynthetic process;2.55002751156269e-28!GO:0044249;cellular biosynthetic process;3.56692338807582e-28!GO:0031981;nuclear lumen;8.71301307403306e-28!GO:0046907;intracellular transport;1.08771424382775e-27!GO:0008380;RNA splicing;2.66412126175528e-27!GO:0006886;intracellular protein transport;2.88097442463333e-27!GO:0005739;mitochondrion;3.07055491466435e-27!GO:0031967;organelle envelope;9.21611828388757e-27!GO:0005840;ribosome;1.4461657509686e-26!GO:0031975;envelope;1.76255575435862e-26!GO:0006397;mRNA processing;8.04140218348578e-26!GO:0003735;structural constituent of ribosome;1.30567414140215e-24!GO:0005830;cytosolic ribosome (sensu Eukaryota);7.06607118808663e-24!GO:0033279;ribosomal subunit;1.74486804129151e-23!GO:0051649;establishment of cellular localization;2.77025788565136e-22!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.86132047672435e-22!GO:0042981;regulation of apoptosis;7.91122818479111e-22!GO:0051641;cellular localization;1.11775454457415e-21!GO:0002376;immune system process;1.599217875788e-21!GO:0043067;regulation of programmed cell death;1.76532374045651e-21!GO:0044445;cytosolic part;2.37195269392332e-21!GO:0000166;nucleotide binding;2.40779817860096e-21!GO:0065003;macromolecular complex assembly;3.74010590758171e-21!GO:0044429;mitochondrial part;6.18162324018288e-21!GO:0005681;spliceosome;1.59046236945821e-20!GO:0008134;transcription factor binding;2.93162476488167e-20!GO:0005654;nucleoplasm;3.20119333042213e-19!GO:0006955;immune response;4.75879890691889e-18!GO:0016192;vesicle-mediated transport;5.15108402649809e-18!GO:0007243;protein kinase cascade;1.0449901701079e-17!GO:0022607;cellular component assembly;2.09092179117362e-17!GO:0022613;ribonucleoprotein complex biogenesis and assembly;2.45046884545221e-17!GO:0006512;ubiquitin cycle;5.30715977150655e-17!GO:0006119;oxidative phosphorylation;5.70522789729059e-17!GO:0044265;cellular macromolecule catabolic process;6.39831910927558e-17!GO:0005740;mitochondrial envelope;6.48079917720548e-17!GO:0048523;negative regulation of cellular process;1.32893617584791e-16!GO:0043412;biopolymer modification;1.63441640748909e-16!GO:0048770;pigment granule;1.63441640748909e-16!GO:0042470;melanosome;1.63441640748909e-16!GO:0031966;mitochondrial membrane;2.31274755002529e-16!GO:0032553;ribonucleotide binding;5.60982654098717e-16!GO:0032555;purine ribonucleotide binding;5.60982654098717e-16!GO:0007249;I-kappaB kinase/NF-kappaB cascade;5.78408043890448e-16!GO:0044451;nucleoplasm part;6.47861795339792e-16!GO:0005773;vacuole;1.31323977652426e-15!GO:0019866;organelle inner membrane;1.52179762106304e-15!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.75435800467545e-15!GO:0016462;pyrophosphatase activity;1.83194154073041e-15!GO:0006464;protein modification process;1.96489030114665e-15!GO:0022618;protein-RNA complex assembly;2.34282371474796e-15!GO:0016817;hydrolase activity, acting on acid anhydrides;2.38915712694957e-15!GO:0043687;post-translational protein modification;3.6810030942875e-15!GO:0043285;biopolymer catabolic process;3.70784963493222e-15!GO:0017076;purine nucleotide binding;3.94328160726491e-15!GO:0017111;nucleoside-triphosphatase activity;4.21719992000062e-15!GO:0019941;modification-dependent protein catabolic process;8.12595452077085e-15!GO:0043632;modification-dependent macromolecule catabolic process;8.12595452077085e-15!GO:0048519;negative regulation of biological process;9.36007755457871e-15!GO:0051603;proteolysis involved in cellular protein catabolic process;1.10372035341843e-14!GO:0044257;cellular protein catabolic process;1.17180854915836e-14!GO:0006511;ubiquitin-dependent protein catabolic process;1.65849721092209e-14!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;2.96683543832605e-14!GO:0000323;lytic vacuole;3.88189001793554e-14!GO:0005764;lysosome;3.88189001793554e-14!GO:0007242;intracellular signaling cascade;4.9130274653754e-14!GO:0003676;nucleic acid binding;7.43589326260935e-14!GO:0006605;protein targeting;8.94262363172916e-14!GO:0009057;macromolecule catabolic process;1.55196991293113e-13!GO:0043069;negative regulation of programmed cell death;1.65202240467219e-13!GO:0043066;negative regulation of apoptosis;2.0003092738748e-13!GO:0050794;regulation of cellular process;2.3709830692945e-13!GO:0016874;ligase activity;3.53728281925649e-13!GO:0016070;RNA metabolic process;4.58201144459571e-13!GO:0006996;organelle organization and biogenesis;5.57422598155734e-13!GO:0016604;nuclear body;5.75573938644686e-13!GO:0006950;response to stress;6.1999906360298e-13!GO:0051246;regulation of protein metabolic process;6.98589523081452e-13!GO:0005743;mitochondrial inner membrane;7.06008042162903e-13!GO:0012505;endomembrane system;7.4774774015123e-13!GO:0006793;phosphorus metabolic process;9.65934961210238e-13!GO:0006796;phosphate metabolic process;9.65934961210238e-13!GO:0000502;proteasome complex (sensu Eukaryota);9.65934961210238e-13!GO:0006913;nucleocytoplasmic transport;1.14064655261459e-12!GO:0044248;cellular catabolic process;1.30532551841344e-12!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.4908285005445e-12!GO:0015934;large ribosomal subunit;1.53144810570385e-12!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;1.64658151192686e-12!GO:0051169;nuclear transport;2.12165689081742e-12!GO:0030163;protein catabolic process;2.73708899072287e-12!GO:0003712;transcription cofactor activity;3.35304691871259e-12!GO:0008135;translation factor activity, nucleic acid binding;3.72245533100145e-12!GO:0006366;transcription from RNA polymerase II promoter;4.06421684459262e-12!GO:0009615;response to virus;4.44778052405561e-12!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);4.85259814175405e-12!GO:0015935;small ribosomal subunit;6.63215105577057e-12!GO:0005794;Golgi apparatus;7.12774710323081e-12!GO:0005768;endosome;7.87704895535653e-12!GO:0065009;regulation of a molecular function;8.04816769373942e-12!GO:0006457;protein folding;9.22581337578989e-12!GO:0016310;phosphorylation;1.65774494479659e-11!GO:0044455;mitochondrial membrane part;1.86854673834838e-11!GO:0050789;regulation of biological process;2.40047696176795e-11!GO:0006916;anti-apoptosis;3.26453968503782e-11!GO:0005524;ATP binding;4.47542918315191e-11!GO:0048522;positive regulation of cellular process;4.60852614434681e-11!GO:0032559;adenyl ribonucleotide binding;6.12778401894776e-11!GO:0016607;nuclear speck;6.60970967948954e-11!GO:0003743;translation initiation factor activity;8.46116710735343e-11!GO:0048518;positive regulation of biological process;9.10198722570879e-11!GO:0006413;translational initiation;1.13684284490907e-10!GO:0005783;endoplasmic reticulum;3.00781760573484e-10!GO:0051186;cofactor metabolic process;3.22168457143218e-10!GO:0030554;adenyl nucleotide binding;4.04209541515405e-10!GO:0009967;positive regulation of signal transduction;4.41002176950041e-10!GO:0006446;regulation of translational initiation;5.01653410405964e-10!GO:0005635;nuclear envelope;5.79412836198522e-10!GO:0065007;biological regulation;6.27677732408138e-10!GO:0031324;negative regulation of cellular metabolic process;1.08097935316358e-09!GO:0006259;DNA metabolic process;1.29040198615326e-09!GO:0005746;mitochondrial respiratory chain;1.44873381511906e-09!GO:0006732;coenzyme metabolic process;1.57925373922536e-09!GO:0051082;unfolded protein binding;2.04636062314642e-09!GO:0008639;small protein conjugating enzyme activity;2.13587829781857e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;2.17754317909883e-09!GO:0019787;small conjugating protein ligase activity;2.73796237134317e-09!GO:0048193;Golgi vesicle transport;2.90244657631289e-09!GO:0000398;nuclear mRNA splicing, via spliceosome;3.1248362009481e-09!GO:0000375;RNA splicing, via transesterification reactions;3.1248362009481e-09!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;3.1248362009481e-09!GO:0004842;ubiquitin-protein ligase activity;3.25548593138555e-09!GO:0005730;nucleolus;3.27083303370057e-09!GO:0006417;regulation of translation;3.37808980610913e-09!GO:0016787;hydrolase activity;4.15284340098481e-09!GO:0005770;late endosome;4.46658640526589e-09!GO:0009607;response to biotic stimulus;5.98903925889038e-09!GO:0015986;ATP synthesis coupled proton transport;6.04216532848451e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;6.04216532848451e-09!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;6.56255531304785e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;7.46781235999326e-09!GO:0050790;regulation of catalytic activity;9.35272541463109e-09!GO:0043065;positive regulation of apoptosis;1.01385581513119e-08!GO:0050136;NADH dehydrogenase (quinone) activity;1.14602914136862e-08!GO:0003954;NADH dehydrogenase activity;1.14602914136862e-08!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.14602914136862e-08!GO:0017038;protein import;1.21348480959546e-08!GO:0019829;cation-transporting ATPase activity;1.32950790393163e-08!GO:0043068;positive regulation of programmed cell death;1.48786174935494e-08!GO:0019899;enzyme binding;1.98143399417098e-08!GO:0009892;negative regulation of metabolic process;2.34078100379375e-08!GO:0051170;nuclear import;2.74992734755727e-08!GO:0048468;cell development;2.81347214899642e-08!GO:0006163;purine nucleotide metabolic process;2.98465929922643e-08!GO:0009056;catabolic process;3.3827550482843e-08!GO:0009150;purine ribonucleotide metabolic process;3.77174442170008e-08!GO:0016564;transcription repressor activity;3.88865269359252e-08!GO:0006164;purine nucleotide biosynthetic process;4.24682259782236e-08!GO:0009152;purine ribonucleotide biosynthetic process;5.06319082845677e-08!GO:0031965;nuclear membrane;5.47882082132027e-08!GO:0009889;regulation of biosynthetic process;5.56619330651057e-08!GO:0006606;protein import into nucleus;6.05176752241271e-08!GO:0051726;regulation of cell cycle;6.82208022726763e-08!GO:0009259;ribonucleotide metabolic process;7.48621723876659e-08!GO:0000074;regulation of progression through cell cycle;8.10140884218616e-08!GO:0016879;ligase activity, forming carbon-nitrogen bonds;8.19856903607519e-08!GO:0003924;GTPase activity;8.24731291260559e-08!GO:0006754;ATP biosynthetic process;8.28978756441826e-08!GO:0006753;nucleoside phosphate metabolic process;8.28978756441826e-08!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;9.0707761033713e-08!GO:0016881;acid-amino acid ligase activity;9.25945467286681e-08!GO:0005525;GTP binding;9.46293351953184e-08!GO:0031326;regulation of cellular biosynthetic process;1.03017515597862e-07!GO:0042775;organelle ATP synthesis coupled electron transport;1.09569707006582e-07!GO:0042773;ATP synthesis coupled electron transport;1.09569707006582e-07!GO:0005774;vacuolar membrane;1.32245497462135e-07!GO:0044432;endoplasmic reticulum part;1.67800850358648e-07!GO:0007049;cell cycle;1.76255005406577e-07!GO:0030964;NADH dehydrogenase complex (quinone);1.95126937239365e-07!GO:0045271;respiratory chain complex I;1.95126937239365e-07!GO:0005747;mitochondrial respiratory chain complex I;1.95126937239365e-07!GO:0042623;ATPase activity, coupled;1.99521269982245e-07!GO:0016481;negative regulation of transcription;1.99521269982245e-07!GO:0009260;ribonucleotide biosynthetic process;2.23134343569485e-07!GO:0006917;induction of apoptosis;2.28079436363628e-07!GO:0016887;ATPase activity;2.28192464388128e-07!GO:0009055;electron carrier activity;2.3737822698282e-07!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;2.39662133596011e-07!GO:0044453;nuclear membrane part;2.40910840271356e-07!GO:0003713;transcription coactivator activity;2.50314333555465e-07!GO:0009966;regulation of signal transduction;2.87509370625619e-07!GO:0005793;ER-Golgi intermediate compartment;3.08469413495418e-07!GO:0008565;protein transporter activity;3.08543647417437e-07!GO:0009108;coenzyme biosynthetic process;3.11099249769152e-07!GO:0046034;ATP metabolic process;3.16627403934647e-07!GO:0051188;cofactor biosynthetic process;3.76252114819902e-07!GO:0012502;induction of programmed cell death;3.78032379274103e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;3.99974626381156e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;3.99974626381156e-07!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;4.10602539153328e-07!GO:0006461;protein complex assembly;4.616826288655e-07!GO:0007264;small GTPase mediated signal transduction;5.07545132583919e-07!GO:0043228;non-membrane-bound organelle;5.20286586355029e-07!GO:0043232;intracellular non-membrane-bound organelle;5.20286586355029e-07!GO:0015078;hydrogen ion transmembrane transporter activity;5.4769365004171e-07!GO:0009142;nucleoside triphosphate biosynthetic process;5.94993500897399e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;5.94993500897399e-07!GO:0044437;vacuolar part;6.90887193805389e-07!GO:0016469;proton-transporting two-sector ATPase complex;7.11139203266925e-07!GO:0044440;endosomal part;7.24051745179605e-07!GO:0010008;endosome membrane;7.24051745179605e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;7.62387232380073e-07!GO:0009144;purine nucleoside triphosphate metabolic process;7.62387232380073e-07!GO:0008047;enzyme activator activity;7.64520591439383e-07!GO:0045786;negative regulation of progression through cell cycle;7.9982369177576e-07!GO:0005765;lysosomal membrane;8.04588979728127e-07!GO:0009199;ribonucleoside triphosphate metabolic process;1.06288784683936e-06!GO:0016044;membrane organization and biogenesis;1.4446947758225e-06!GO:0006954;inflammatory response;1.5255158800265e-06!GO:0019222;regulation of metabolic process;1.53394242983111e-06!GO:0032561;guanyl ribonucleotide binding;1.62903523784495e-06!GO:0019001;guanyl nucleotide binding;1.62903523784495e-06!GO:0006752;group transfer coenzyme metabolic process;1.9170727077428e-06!GO:0009141;nucleoside triphosphate metabolic process;2.61329305469198e-06!GO:0004386;helicase activity;3.05321467692015e-06!GO:0005839;proteasome core complex (sensu Eukaryota);3.25618624357071e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;3.45441147541873e-06!GO:0042175;nuclear envelope-endoplasmic reticulum network;3.5713407337485e-06!GO:0005789;endoplasmic reticulum membrane;3.88364570553681e-06!GO:0031980;mitochondrial lumen;4.08908983014137e-06!GO:0005759;mitochondrial matrix;4.08908983014137e-06!GO:0032446;protein modification by small protein conjugation;4.4680241467408e-06!GO:0016563;transcription activator activity;4.72895315123656e-06!GO:0031982;vesicle;5.29253442124714e-06!GO:0045321;leukocyte activation;7.25662576701924e-06!GO:0008026;ATP-dependent helicase activity;7.33477181220367e-06!GO:0016567;protein ubiquitination;7.3505321495947e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;7.44054945301441e-06!GO:0005643;nuclear pore;9.59458664988168e-06!GO:0050657;nucleic acid transport;9.89306742313036e-06!GO:0051236;establishment of RNA localization;9.89306742313036e-06!GO:0050658;RNA transport;9.89306742313036e-06!GO:0006888;ER to Golgi vesicle-mediated transport;1.33599801130803e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;1.3500615101833e-05!GO:0006325;establishment and/or maintenance of chromatin architecture;1.35407757294434e-05!GO:0006403;RNA localization;1.35752611931581e-05!GO:0006974;response to DNA damage stimulus;1.44122720249827e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;1.45937941100827e-05!GO:0015399;primary active transmembrane transporter activity;1.45937941100827e-05!GO:0003714;transcription corepressor activity;1.45937941100827e-05!GO:0004298;threonine endopeptidase activity;1.45937941100827e-05!GO:0006357;regulation of transcription from RNA polymerase II promoter;1.91080955025545e-05!GO:0001816;cytokine production;2.30281631308116e-05!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;2.48742446602195e-05!GO:0030099;myeloid cell differentiation;2.83698707964426e-05!GO:0031902;late endosome membrane;2.94092666944903e-05!GO:0016568;chromatin modification;2.95412443156077e-05!GO:0006323;DNA packaging;3.14057741582433e-05!GO:0016197;endosome transport;3.14398621475457e-05!GO:0031252;leading edge;3.18969773293238e-05!GO:0031410;cytoplasmic vesicle;3.23375105547352e-05!GO:0031988;membrane-bound vesicle;3.32051532947102e-05!GO:0006952;defense response;3.42286026236298e-05!GO:0003724;RNA helicase activity;3.82011476580925e-05!GO:0030097;hemopoiesis;3.94304223002622e-05!GO:0032940;secretion by cell;4.61788803294826e-05!GO:0006897;endocytosis;4.68762297133931e-05!GO:0010324;membrane invagination;4.68762297133931e-05!GO:0051707;response to other organism;4.74583830968274e-05!GO:0043566;structure-specific DNA binding;5.3686652807597e-05!GO:0006401;RNA catabolic process;5.4499988726262e-05!GO:0048475;coated membrane;5.68818818236335e-05!GO:0030117;membrane coat;5.68818818236335e-05!GO:0030120;vesicle coat;5.68818818236335e-05!GO:0030662;coated vesicle membrane;5.68818818236335e-05!GO:0008632;apoptotic program;7.06242888923442e-05!GO:0051338;regulation of transferase activity;7.26262970601364e-05!GO:0022402;cell cycle process;7.44530952695053e-05!GO:0051336;regulation of hydrolase activity;7.45339061829351e-05!GO:0051789;response to protein stimulus;7.60823444311154e-05!GO:0006986;response to unfolded protein;7.60823444311154e-05!GO:0030695;GTPase regulator activity;8.14036249907502e-05!GO:0045259;proton-transporting ATP synthase complex;8.25469442259637e-05!GO:0005096;GTPase activator activity;8.33142660687945e-05!GO:0046930;pore complex;8.89210098667148e-05!GO:0009060;aerobic respiration;9.2039945106269e-05!GO:0016023;cytoplasmic membrane-bound vesicle;0.000103117507445617!GO:0051028;mRNA transport;0.000104506031070362!GO:0030532;small nuclear ribonucleoprotein complex;0.000111618349752972!GO:0006613;cotranslational protein targeting to membrane;0.000112408061118268!GO:0008234;cysteine-type peptidase activity;0.000117450428871156!GO:0004674;protein serine/threonine kinase activity;0.000125726366570019!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;0.000126320276144544!GO:0043549;regulation of kinase activity;0.000144940227463859!GO:0045892;negative regulation of transcription, DNA-dependent;0.000157611641871477!GO:0000245;spliceosome assembly;0.000161512204793827!GO:0009893;positive regulation of metabolic process;0.000163305243260152!GO:0043492;ATPase activity, coupled to movement of substances;0.000165728186943657!GO:0046822;regulation of nucleocytoplasmic transport;0.000166905944448615!GO:0046649;lymphocyte activation;0.000167275449054843!GO:0031323;regulation of cellular metabolic process;0.000169652740672729!GO:0005769;early endosome;0.000171087250785435!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000178303607087306!GO:0003697;single-stranded DNA binding;0.00018151062055302!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;0.000192109158503039!GO:0006281;DNA repair;0.000212023024561384!GO:0045859;regulation of protein kinase activity;0.000233871105771492!GO:0031202;RNA splicing factor activity, transesterification mechanism;0.000237570613368701!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000267206617023361!GO:0006818;hydrogen transport;0.000267206617023361!GO:0051168;nuclear export;0.000274531979936221!GO:0065002;intracellular protein transport across a membrane;0.000275388436303511!GO:0005885;Arp2/3 protein complex;0.000285891486530656!GO:0042254;ribosome biogenesis and assembly;0.000287159539587084!GO:0007005;mitochondrion organization and biogenesis;0.000295585132700792!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000299773381029585!GO:0001775;cell activation;0.000300114964785508!GO:0045333;cellular respiration;0.000317428483353756!GO:0009611;response to wounding;0.000317428483353756!GO:0046983;protein dimerization activity;0.000368257863461564!GO:0015992;proton transport;0.000375258389891329!GO:0046519;sphingoid metabolic process;0.000376582128655279!GO:0005057;receptor signaling protein activity;0.000391422282680057!GO:0051223;regulation of protein transport;0.000403596520787655!GO:0000151;ubiquitin ligase complex;0.000406937963124142!GO:0008186;RNA-dependent ATPase activity;0.000408480923304494!GO:0008654;phospholipid biosynthetic process;0.000419466371507872!GO:0044431;Golgi apparatus part;0.00045790061284927!GO:0005761;mitochondrial ribosome;0.000467967608143487!GO:0000313;organellar ribosome;0.000467967608143487!GO:0016740;transferase activity;0.000485523680265403!GO:0002757;immune response-activating signal transduction;0.000509370634271621!GO:0007050;cell cycle arrest;0.000509610460400453!GO:0005798;Golgi-associated vesicle;0.000517256119069156!GO:0002520;immune system development;0.000517256119069156!GO:0030036;actin cytoskeleton organization and biogenesis;0.000519619671521692!GO:0006402;mRNA catabolic process;0.000552536067562177!GO:0005083;small GTPase regulator activity;0.000579166394497797!GO:0007040;lysosome organization and biogenesis;0.000581928563049053!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000581928563049053!GO:0002521;leukocyte differentiation;0.000585884941251734!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000608591700867387!GO:0007041;lysosomal transport;0.000649403935094906!GO:0006672;ceramide metabolic process;0.000661367954229181!GO:0007034;vacuolar transport;0.000705494839435764!GO:0051276;chromosome organization and biogenesis;0.000723813317547041!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.000726935509944493!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.000730216726845309!GO:0016281;eukaryotic translation initiation factor 4F complex;0.000740616117656623!GO:0022890;inorganic cation transmembrane transporter activity;0.00080449445524663!GO:0009117;nucleotide metabolic process;0.000807758135634016!GO:0005741;mitochondrial outer membrane;0.000838174461603207!GO:0006399;tRNA metabolic process;0.000866765115813374!GO:0019221;cytokine and chemokine mediated signaling pathway;0.000876079893706264!GO:0048534;hemopoietic or lymphoid organ development;0.000878440660596497!GO:0051427;hormone receptor binding;0.000879836626212479!GO:0042110;T cell activation;0.000879836626212479!GO:0002764;immune response-regulating signal transduction;0.00092788157145369!GO:0005637;nuclear inner membrane;0.00092788157145369!GO:0060090;molecular adaptor activity;0.000946736524524776!GO:0045637;regulation of myeloid cell differentiation;0.000986201459527429!GO:0033157;regulation of intracellular protein transport;0.00102976969099126!GO:0042306;regulation of protein import into nucleus;0.00102976969099126!GO:0001726;ruffle;0.0010828630423798!GO:0043281;regulation of caspase activity;0.00109797710450535!GO:0004004;ATP-dependent RNA helicase activity;0.00111800848106136!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.00112014529171915!GO:0007259;JAK-STAT cascade;0.00113155403948248!GO:0043085;positive regulation of catalytic activity;0.00113698186355569!GO:0007265;Ras protein signal transduction;0.00113698186355569!GO:0016301;kinase activity;0.00114150086444463!GO:0003729;mRNA binding;0.00117991648922197!GO:0007033;vacuole organization and biogenesis;0.00119151599849168!GO:0045893;positive regulation of transcription, DNA-dependent;0.00119941799360402!GO:0006643;membrane lipid metabolic process;0.00120727019185797!GO:0045941;positive regulation of transcription;0.00123724362721024!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00123927188585535!GO:0009719;response to endogenous stimulus;0.00124266644861556!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;0.00127130499366558!GO:0004812;aminoacyl-tRNA ligase activity;0.00127130499366558!GO:0016875;ligase activity, forming carbon-oxygen bonds;0.00127130499366558!GO:0002274;myeloid leukocyte activation;0.00131596495492106!GO:0010468;regulation of gene expression;0.00132246594916705!GO:0002252;immune effector process;0.00136837083553879!GO:0045045;secretory pathway;0.00138523967417726!GO:0035257;nuclear hormone receptor binding;0.00138523967417726!GO:0030149;sphingolipid catabolic process;0.00138523967417726!GO:0022415;viral reproductive process;0.00143373478250771!GO:0005667;transcription factor complex;0.00144212483112282!GO:0033116;ER-Golgi intermediate compartment membrane;0.00162258760925529!GO:0045454;cell redox homeostasis;0.0017637190401206!GO:0018193;peptidyl-amino acid modification;0.00177706080626968!GO:0031325;positive regulation of cellular metabolic process;0.00178569649334751!GO:0043038;amino acid activation;0.00182091199846927!GO:0006418;tRNA aminoacylation for protein translation;0.00182091199846927!GO:0043039;tRNA aminoacylation;0.00182091199846927!GO:0006612;protein targeting to membrane;0.00191947657757119!GO:0019904;protein domain specific binding;0.00207385472701271!GO:0006919;caspase activation;0.00211612851325074!GO:0006099;tricarboxylic acid cycle;0.00211780636290908!GO:0046356;acetyl-CoA catabolic process;0.00211780636290908!GO:0043280;positive regulation of caspase activity;0.00214178457887828!GO:0006468;protein amino acid phosphorylation;0.00223001045379519!GO:0051090;regulation of transcription factor activity;0.00237883524623019!GO:0031072;heat shock protein binding;0.00261525672918221!GO:0002429;immune response-activating cell surface receptor signaling pathway;0.00261525672918221!GO:0016779;nucleotidyltransferase activity;0.00265236296957877!GO:0002250;adaptive immune response;0.00276484557886276!GO:0002460;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.00276484557886276!GO:0051187;cofactor catabolic process;0.00279508398164841!GO:0042990;regulation of transcription factor import into nucleus;0.00287759513127205!GO:0042991;transcription factor import into nucleus;0.00287759513127205!GO:0043623;cellular protein complex assembly;0.00291805663795786!GO:0019882;antigen processing and presentation;0.00301925440558313!GO:0003702;RNA polymerase II transcription factor activity;0.00303804722974034!GO:0031968;organelle outer membrane;0.00311790210803431!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00313967417718184!GO:0019867;outer membrane;0.00338420138465172!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.00343151531451702!GO:0030029;actin filament-based process;0.00345826059786722!GO:0004197;cysteine-type endopeptidase activity;0.00352049098547478!GO:0016251;general RNA polymerase II transcription factor activity;0.00352650730987938!GO:0005099;Ras GTPase activator activity;0.00354252309349815!GO:0044262;cellular carbohydrate metabolic process;0.00360436595682734!GO:0065004;protein-DNA complex assembly;0.00367556690086796!GO:0043087;regulation of GTPase activity;0.00407439915386591!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00407439915386591!GO:0033673;negative regulation of kinase activity;0.00450216475585569!GO:0006469;negative regulation of protein kinase activity;0.00450216475585569!GO:0002768;immune response-regulating cell surface receptor signaling pathway;0.00453318036837557!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00459985813684744!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00459985813684744!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00459985813684744!GO:0006084;acetyl-CoA metabolic process;0.00552150195853272!GO:0006091;generation of precursor metabolites and energy;0.00557398889527398!GO:0051348;negative regulation of transferase activity;0.00575654432446077!GO:0048487;beta-tubulin binding;0.00609070874234875!GO:0016363;nuclear matrix;0.00609357519099124!GO:0009109;coenzyme catabolic process;0.00613486000707461!GO:0006891;intra-Golgi vesicle-mediated transport;0.00615984324192054!GO:0031901;early endosome membrane;0.00645657702203849!GO:0019377;glycolipid catabolic process;0.00645657702203849!GO:0006607;NLS-bearing substrate import into nucleus;0.00662641154493419!GO:0008383;manganese superoxide dismutase activity;0.00667532253215363!GO:0001315;age-dependent response to reactive oxygen species;0.00667532253215363!GO:0032386;regulation of intracellular transport;0.00675837429322067!GO:0001817;regulation of cytokine production;0.00675837429322067!GO:0006364;rRNA processing;0.00676409540479221!GO:0016072;rRNA metabolic process;0.00682283417291033!GO:0003690;double-stranded DNA binding;0.00683368700348186!GO:0005070;SH3/SH2 adaptor activity;0.00704829187477151!GO:0006350;transcription;0.00717713419528557!GO:0048471;perinuclear region of cytoplasm;0.00723191361238526!GO:0004185;serine carboxypeptidase activity;0.00763201083705197!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.0077937246822703!GO:0009165;nucleotide biosynthetic process;0.00801725663931066!GO:0043433;negative regulation of transcription factor activity;0.00809818444190524!GO:0046467;membrane lipid biosynthetic process;0.00813966633420696!GO:0000139;Golgi membrane;0.00821267039561583!GO:0045639;positive regulation of myeloid cell differentiation;0.00847972748102581!GO:0042613;MHC class II protein complex;0.00881032006639826!GO:0006458;'de novo' protein folding;0.0091774235728781!GO:0051084;'de novo' posttranslational protein folding;0.0091774235728781!GO:0002684;positive regulation of immune system process;0.00923303924257253!GO:0050851;antigen receptor-mediated signaling pathway;0.0097131854456169!GO:0002443;leukocyte mediated immunity;0.0101210366898214!GO:0019079;viral genome replication;0.0101210366898214!GO:0008637;apoptotic mitochondrial changes;0.0101386429117248!GO:0006333;chromatin assembly or disassembly;0.0102428847537586!GO:0002682;regulation of immune system process;0.0103721832989771!GO:0043021;ribonucleoprotein binding;0.0104763468087059!GO:0004860;protein kinase inhibitor activity;0.0105510640749631!GO:0031625;ubiquitin protein ligase binding;0.0105803946813719!GO:0030867;rough endoplasmic reticulum membrane;0.0107166250344401!GO:0030134;ER to Golgi transport vesicle;0.010868412172018!GO:0030127;COPII vesicle coat;0.010888495789851!GO:0012507;ER to Golgi transport vesicle membrane;0.010888495789851!GO:0019210;kinase inhibitor activity;0.0109601085340232!GO:0000785;chromatin;0.0109922050985273!GO:0002440;production of molecular mediator of immune response;0.0109927089443808!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0112107062414965!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.0115986817419871!GO:0042802;identical protein binding;0.0119343314986795!GO:0004177;aminopeptidase activity;0.0122780749836563!GO:0042113;B cell activation;0.0123849675641616!GO:0050778;positive regulation of immune response;0.0126061802554065!GO:0006611;protein export from nucleus;0.0127374421284383!GO:0006749;glutathione metabolic process;0.0127853493700093!GO:0003725;double-stranded RNA binding;0.0128838034536237!GO:0042611;MHC protein complex;0.0134033648826649!GO:0030658;transport vesicle membrane;0.013773809112932!GO:0005484;SNAP receptor activity;0.0139960716260302!GO:0019220;regulation of phosphate metabolic process;0.0139964202227722!GO:0051174;regulation of phosphorus metabolic process;0.0139964202227722!GO:0005048;signal sequence binding;0.0140435443318953!GO:0051059;NF-kappaB binding;0.0141091326616962!GO:0051345;positive regulation of hydrolase activity;0.0142771497902115!GO:0006665;sphingolipid metabolic process;0.0143628713271464!GO:0032763;regulation of mast cell cytokine production;0.0143628713271464!GO:0032762;mast cell cytokine production;0.0143628713271464!GO:0002467;germinal center formation;0.0144783055135957!GO:0046479;glycosphingolipid catabolic process;0.0146605796358293!GO:0030218;erythrocyte differentiation;0.0152261860622508!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0161195904641282!GO:0048002;antigen processing and presentation of peptide antigen;0.0163731378749894!GO:0002822;regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.;0.0163731378749894!GO:0002819;regulation of adaptive immune response;0.0163731378749894!GO:0030176;integral to endoplasmic reticulum membrane;0.0163731378749894!GO:0042221;response to chemical stimulus;0.0165389142443364!GO:0048500;signal recognition particle;0.0168897417218311!GO:0043621;protein self-association;0.0174723987345351!GO:0008629;induction of apoptosis by intracellular signals;0.0175875321653887!GO:0006354;RNA elongation;0.0179122696632736!GO:0046466;membrane lipid catabolic process;0.0179556350037202!GO:0005813;centrosome;0.0181601192870879!GO:0000209;protein polyubiquitination;0.0181601192870879!GO:0008286;insulin receptor signaling pathway;0.0182089905216569!GO:0046966;thyroid hormone receptor binding;0.0183271757016091!GO:0006352;transcription initiation;0.0183911003403251!GO:0030041;actin filament polymerization;0.0184646246070164!GO:0019883;antigen processing and presentation of endogenous antigen;0.0187780233470636!GO:0002237;response to molecule of bacterial origin;0.0187780233470636!GO:0051049;regulation of transport;0.0188195987334897!GO:0030224;monocyte differentiation;0.0188859276536995!GO:0051247;positive regulation of protein metabolic process;0.0189371799576868!GO:0051252;regulation of RNA metabolic process;0.0189745801353442!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0191512770601006!GO:0030693;caspase activity;0.0195349165480879!GO:0000287;magnesium ion binding;0.0198071913199015!GO:0002253;activation of immune response;0.0202404685304707!GO:0002444;myeloid leukocyte mediated immunity;0.0202577544204063!GO:0008139;nuclear localization sequence binding;0.0203698170346734!GO:0043071;positive regulation of non-apoptotic programmed cell death;0.0207145718937462!GO:0030133;transport vesicle;0.0210299954615538!GO:0000082;G1/S transition of mitotic cell cycle;0.0211246641206747!GO:0006414;translational elongation;0.021189379038295!GO:0017166;vinculin binding;0.0213991578437528!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0218863776376415!GO:0045047;protein targeting to ER;0.0218863776376415!GO:0046979;TAP2 binding;0.0219350720012419!GO:0046977;TAP binding;0.0219350720012419!GO:0046978;TAP1 binding;0.0219350720012419!GO:0019318;hexose metabolic process;0.0220228281269715!GO:0006650;glycerophospholipid metabolic process;0.0220228281269715!GO:0050776;regulation of immune response;0.0220320751000647!GO:0043300;regulation of leukocyte degranulation;0.0220320751000647!GO:0002224;toll-like receptor signaling pathway;0.0228835313571859!GO:0002221;pattern recognition receptor signaling pathway;0.0228835313571859!GO:0030518;steroid hormone receptor signaling pathway;0.022949568163103!GO:0015631;tubulin binding;0.023474875197036!GO:0051098;regulation of binding;0.0238244936409691!GO:0030503;regulation of cell redox homeostasis;0.02393983748502!GO:0017091;AU-rich element binding;0.02393983748502!GO:0050779;RNA destabilization;0.02393983748502!GO:0000289;poly(A) tail shortening;0.02393983748502!GO:0005791;rough endoplasmic reticulum;0.0241390678810738!GO:0015036;disulfide oxidoreductase activity;0.0243759770685864!GO:0001819;positive regulation of cytokine production;0.0244957308935191!GO:0045792;negative regulation of cell size;0.0244957308935191!GO:0032318;regulation of Ras GTPase activity;0.0245028006309136!GO:0048146;positive regulation of fibroblast proliferation;0.0252343195690764!GO:0050900;leukocyte migration;0.0252400490904286!GO:0005905;coated pit;0.0252400490904286!GO:0016791;phosphoric monoester hydrolase activity;0.0252905547308972!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0253940015388987!GO:0000118;histone deacetylase complex;0.0256528101497422!GO:0033367;protein localization in mast cell secretory granule;0.0256528101497422!GO:0033365;protein localization in organelle;0.0256528101497422!GO:0033371;T cell secretory granule organization and biogenesis;0.0256528101497422!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.0256528101497422!GO:0033375;protease localization in T cell secretory granule;0.0256528101497422!GO:0042629;mast cell granule;0.0256528101497422!GO:0033377;maintenance of protein localization in T cell secretory granule;0.0256528101497422!GO:0033364;mast cell secretory granule organization and biogenesis;0.0256528101497422!GO:0033380;granzyme B localization in T cell secretory granule;0.0256528101497422!GO:0033379;maintenance of protease localization in T cell secretory granule;0.0256528101497422!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.0256528101497422!GO:0033368;protease localization in mast cell secretory granule;0.0256528101497422!GO:0033366;protein localization in secretory granule;0.0256528101497422!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.0256528101497422!GO:0033374;protein localization in T cell secretory granule;0.0256528101497422!GO:0000049;tRNA binding;0.0257318668943842!GO:0051085;chaperone cofactor-dependent protein folding;0.0258003688894064!GO:0043022;ribosome binding;0.0264920330378117!GO:0019783;small conjugating protein-specific protease activity;0.0275301638360637!GO:0051092;activation of NF-kappaB transcription factor;0.0275663618952515!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0275889722748301!GO:0003727;single-stranded RNA binding;0.02760241133351!GO:0005996;monosaccharide metabolic process;0.0277552801975843!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0281024775834899!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0281024775834899!GO:0030663;COPI coated vesicle membrane;0.0282730338834748!GO:0030126;COPI vesicle coat;0.0282730338834748!GO:0030308;negative regulation of cell growth;0.0283222002783204!GO:0030027;lamellipodium;0.0286308790599931!GO:0042108;positive regulation of cytokine biosynthetic process;0.0288903683618102!GO:0030660;Golgi-associated vesicle membrane;0.0291251435422073!GO:0051051;negative regulation of transport;0.0291251435422073!GO:0000339;RNA cap binding;0.0292888991176659!GO:0030258;lipid modification;0.0299424534021749!GO:0006644;phospholipid metabolic process;0.0300028319949856!GO:0030137;COPI-coated vesicle;0.0300028319949856!GO:0048144;fibroblast proliferation;0.0300028319949856!GO:0048145;regulation of fibroblast proliferation;0.0300028319949856!GO:0030217;T cell differentiation;0.0302181731479812!GO:0019901;protein kinase binding;0.0302690905603346!GO:0050811;GABA receptor binding;0.0302690905603346!GO:0000165;MAPKKK cascade;0.0304462206588323!GO:0045646;regulation of erythrocyte differentiation;0.030460041880415!GO:0002824;positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.030460041880415!GO:0002821;positive regulation of adaptive immune response;0.030460041880415!GO:0051540;metal cluster binding;0.0304709813010475!GO:0051536;iron-sulfur cluster binding;0.0304709813010475!GO:0030521;androgen receptor signaling pathway;0.0304947563162316!GO:0043488;regulation of mRNA stability;0.031310635701397!GO:0043487;regulation of RNA stability;0.031310635701397!GO:0051325;interphase;0.0315654418059!GO:0015923;mannosidase activity;0.031792925716835!GO:0051329;interphase of mitotic cell cycle;0.031888699459416!GO:0030100;regulation of endocytosis;0.0319240209800773!GO:0008333;endosome to lysosome transport;0.0319240209800773!GO:0051101;regulation of DNA binding;0.0319240209800773!GO:0019843;rRNA binding;0.0321571539399297!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.032747798371073!GO:0019058;viral infectious cycle;0.0329879359091023!GO:0030384;phosphoinositide metabolic process;0.0332110219073328!GO:0004843;ubiquitin-specific protease activity;0.0332510973582797!GO:0005788;endoplasmic reticulum lumen;0.0332697037270126!GO:0030098;lymphocyte differentiation;0.0334396826451517!GO:0045576;mast cell activation;0.0338547752555254!GO:0007006;mitochondrial membrane organization and biogenesis;0.0344652846250075!GO:0002573;myeloid leukocyte differentiation;0.0349933169591218!GO:0016605;PML body;0.0349933169591218!GO:0008312;7S RNA binding;0.0349933169591218!GO:0030433;ER-associated protein catabolic process;0.0349933169591218!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0349933169591218!GO:0045944;positive regulation of transcription from RNA polymerase II promoter;0.0354472542685927!GO:0032760;positive regulation of tumor necrosis factor production;0.0354478119859083!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0355371422506446!GO:0003746;translation elongation factor activity;0.0360456732822696!GO:0051235;maintenance of localization;0.0362638971395747!GO:0042348;NF-kappaB import into nucleus;0.0368477740896377!GO:0042345;regulation of NF-kappaB import into nucleus;0.0368477740896377!GO:0005684;U2-dependent spliceosome;0.0372195423185497!GO:0005815;microtubule organizing center;0.0375139864410376!GO:0030118;clathrin coat;0.039000917941304!GO:0048872;homeostasis of number of cells;0.0391069756158379!GO:0008283;cell proliferation;0.0394154909467805!GO:0008624;induction of apoptosis by extracellular signals;0.0412006223431908!GO:0033549;MAP kinase phosphatase activity;0.041223547225493!GO:0017017;MAP kinase tyrosine/serine/threonine phosphatase activity;0.041223547225493!GO:0051052;regulation of DNA metabolic process;0.0412514256459917!GO:0031327;negative regulation of cellular biosynthetic process;0.041463480948956!GO:0005669;transcription factor TFIID complex;0.0422201463347051!GO:0002449;lymphocyte mediated immunity;0.04245729148319!GO:0051050;positive regulation of transport;0.04245729148319!GO:0008361;regulation of cell size;0.04298348818071!GO:0006509;membrane protein ectodomain proteolysis;0.0430896094169779!GO:0033619;membrane protein proteolysis;0.0430896094169779!GO:0006516;glycoprotein catabolic process;0.0431403611337674!GO:0005694;chromosome;0.0435080765511887!GO:0006465;signal peptide processing;0.043534008902192!GO:0006689;ganglioside catabolic process;0.0438312966475632!GO:0046426;negative regulation of JAK-STAT cascade;0.0439640951324241!GO:0042325;regulation of phosphorylation;0.0440537489585568!GO:0006984;ER-nuclear signaling pathway;0.044472665047817!GO:0005869;dynactin complex;0.0449146185471537!GO:0001836;release of cytochrome c from mitochondria;0.0451169407004961!GO:0003711;transcription elongation regulator activity;0.0455733113163864!GO:0045309;protein phosphorylated amino acid binding;0.0455733113163864!GO:0033033;negative regulation of myeloid cell apoptosis;0.0455733113163864!GO:0001803;regulation of type III hypersensitivity;0.0455733113163864!GO:0032733;positive regulation of interleukin-10 production;0.0455733113163864!GO:0033025;regulation of mast cell apoptosis;0.0455733113163864!GO:0001805;positive regulation of type III hypersensitivity;0.0455733113163864!GO:0033023;mast cell homeostasis;0.0455733113163864!GO:0002431;Fc receptor mediated stimulatory signaling pathway;0.0455733113163864!GO:0033032;regulation of myeloid cell apoptosis;0.0455733113163864!GO:0001802;type III hypersensitivity;0.0455733113163864!GO:0033028;myeloid cell apoptosis;0.0455733113163864!GO:0042590;antigen processing and presentation of exogenous peptide antigen via MHC class I;0.0455733113163864!GO:0033026;negative regulation of mast cell apoptosis;0.0455733113163864!GO:0033024;mast cell apoptosis;0.0455733113163864!GO:0043299;leukocyte degranulation;0.0463490074275165!GO:0045746;negative regulation of Notch signaling pathway;0.0475362695043483!GO:0002697;regulation of immune effector process;0.0475362695043483!GO:0001516;prostaglandin biosynthetic process;0.047763463128988!GO:0046457;prostanoid biosynthetic process;0.047763463128988!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0478896815485094!GO:0007162;negative regulation of cell adhesion;0.0479773354199197!GO:0051023;regulation of immunoglobulin secretion;0.0481219233255432!GO:0045994;positive regulation of translational initiation by iron;0.0481219233255432!GO:0009306;protein secretion;0.0483043849118032!GO:0051251;positive regulation of lymphocyte activation;0.0484588616538756!GO:0008538;proteasome activator activity;0.0486051391800607!GO:0006376;mRNA splice site selection;0.0486051391800607!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0486051391800607!GO:0000278;mitotic cell cycle;0.0488216749270155!GO:0043304;regulation of mast cell degranulation;0.0489184039002272!GO:0051347;positive regulation of transferase activity;0.0491242412578323!GO:0019900;kinase binding;0.0491242412578323!GO:0002718;regulation of cytokine production during immune response;0.0492657164905609!GO:0002367;cytokine production during immune response;0.0492657164905609!GO:0002700;regulation of production of molecular mediator of immune response;0.0492657164905609!GO:0019752;carboxylic acid metabolic process;0.0499990664378636 | |||
|sample_id=11870 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue= | |||
|top_motifs=STAT2,4,6:5.6873180702;STAT5{A,B}:5.0760598675;NFE2:4.65898972643;FOSL2:4.51699774424;IRF7:4.37666428933;STAT1,3:4.35731913977;NFE2L2:4.30464233454;CEBPA,B_DDIT3:4.25343635409;IRF1,2:4.04942952684;BACH2:4.04449793903;FOS_FOS{B,L1}_JUN{B,D}:3.93877530274;PAX2:3.81814875974;HLF:3.75394877891;SPIB:3.15935565633;NANOG{mouse}:2.91180948729;SREBF1,2:2.88191990142;SPI1:2.87026886345;ETS1,2:2.6609524874;NFKB1_REL_RELA:2.6520852099;NFIL3:2.61402352228;NR1H4:2.59670030543;FOXP3:2.45582888747;DMAP1_NCOR{1,2}_SMARC:2.43026700202;EP300:2.42204088476;ATF4:2.30299643723;ATF5_CREB3:2.30063116651;NFE2L1:2.18351912136;ATF6:2.16998033433;RUNX1..3:1.96582741093;FOXN1:1.93005147584;HSF1,2:1.87487964078;CREB1:1.86743276206;JUN:1.71762497471;ATF2:1.59887352137;TGIF1:1.54147464543;NFATC1..3:1.45861019126;ELF1,2,4:1.45519624723;ALX4:1.32733870701;HIF1A:1.28042868529;CDX1,2,4:1.27045570132;PDX1:1.23989793587;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.20438362811;MAFB:1.10730731647;PAX8:1.06146334655;XBP1:0.879268800458;GLI1..3:0.811849149249;PAX3,7:0.706019063101;ZBTB16:0.65421279013;PPARG:0.632979141294;RXRA_VDR{dimer}:0.597746605104;TLX2:0.491696046027;SRF:0.480293920921;BPTF:0.378394826692;HOX{A5,B5}:0.362230512703;NR6A1:0.359261286569;TFCP2:0.2706289965;FOXD3:0.254445309164;PRDM1:0.240655049559;HMGA1,2:0.213372334137;HMX1:0.173184400016;ESRRA:0.152242075381;AHR_ARNT_ARNT2:0.132044413194;TBP:0.131300247182;SMAD1..7,9:0.10401074364;HBP1_HMGB_SSRP1_UBTF:0.0903711470538;GATA4:0.0609816963918;NANOG:0.0308285279103;SPZ1:-0.0340430392294;IKZF1:-0.0537015508883;ESR1:-0.119762955786;EN1,2:-0.129168588362;HOXA9_MEIS1:-0.147854964283;MEF2{A,B,C,D}:-0.158855206145;PITX1..3:-0.189901984093;PAX4:-0.236961034429;RBPJ:-0.285108842133;EGR1..3:-0.2898250058;FOXO1,3,4:-0.293444446195;FOXM1:-0.301112159967;IKZF2:-0.303323878275;VSX1,2:-0.334305959497;RFX2..5_RFXANK_RFXAP:-0.349683894424;HES1:-0.363505246943;FOX{D1,D2}:-0.384115098271;MYB:-0.431102294032;OCT4_SOX2{dimer}:-0.469608004519;POU2F1..3:-0.62755594224;NKX6-1,2:-0.667491822794;FOXL1:-0.700410062435;MZF1:-0.712075369692;RORA:-0.746490856563;FOXP1:-0.825871659475;HOX{A6,A7,B6,B7}:-0.829429625931;FOX{F1,F2,J1}:-0.858882804135;TFAP4:-0.859939776446;POU5F1:-0.889720753217;DBP:-0.912120662464;RXR{A,B,G}:-0.947159205991;ALX1:-0.950573598829;PAX1,9:-0.950948549814;NHLH1,2:-0.955030893442;TAL1_TCF{3,4,12}:-1.00253623467;SOX2:-1.01374005283;HNF4A_NR2F1,2:-1.01398211579;REST:-1.0313278966;PAX6:-1.04660947468;HNF1A:-1.08437701441;MED-1{core}:-1.12999793335;NKX2-2,8:-1.13289677107;MYFfamily:-1.14624260247;ZNF238:-1.19868210379;PRRX1,2:-1.21835112174;POU6F1:-1.22304536787;MTE{core}:-1.23061295819;RXR{A,B,G}_{NR1H2,PPAR}dimers:-1.25476172027;NKX3-2:-1.30726290505;NR3C1:-1.32733655755;NKX3-1:-1.39151050107;SOX5:-1.40585256815;GCM1,2:-1.41576984373;GZF1:-1.45047621508;RREB1:-1.4516845404;GATA6:-1.50029763425;ZBTB6:-1.50462194843;TFAP2B:-1.51169339269;PATZ1:-1.52066178947;CUX2:-1.547762325;MTF1:-1.55945446376;NFIX:-1.59383003143;ZFP161:-1.60716535541;NKX2-1,4:-1.61257058626;NKX2-3_NKX2-5:-1.62305034824;TEAD1:-1.63264209622;XCPE1{core}:-1.64580942982;E2F1..5:-1.66828898113;MYOD1:-1.67059816496;GTF2A1,2:-1.67177462065;TFDP1:-1.68599113809;CDC5L:-1.70862361806;POU3F1..4:-1.73333201266;GTF2I:-1.74644792137;BREu{core}:-1.74788534426;ZEB1:-1.75609424618;TP53:-1.7768962541;RFX1:-1.78668197341;ZNF148:-1.78987490168;TLX1..3_NFIC{dimer}:-1.79771632203;SP1:-1.81194192504;MAZ:-1.81292007886;POU1F1:-1.81480209425;T:-1.8242021726;MYBL2:-1.8642772328;ONECUT1,2:-1.86710117046;FOXA2:-1.8842027459;SOX{8,9,10}:-1.88639226273;ZNF384:-1.91273898361;SNAI1..3:-1.91499472415;UFEwm:-1.98441838156;TBX4,5:-1.99062227175;GFI1B:-2.03147721014;TFAP2{A,C}:-2.03876623886;CRX:-2.052388287;HIC1:-2.05243308785;ELK1,4_GABP{A,B1}:-2.07874640024;KLF4:-2.14460350378;ADNP_IRX_SIX_ZHX:-2.14592994191;HAND1,2:-2.21748932401;TOPORS:-2.24570760513;ZIC1..3:-2.30588304011;bHLH_family:-2.33877411188;EBF1:-2.38805943486;AIRE:-2.39217826611;FOXQ1:-2.40082984548;LMO2:-2.41217477326;TEF:-2.41474953284;NFY{A,B,C}:-2.41949473486;HOX{A4,D4}:-2.42485636677;EVI1:-2.48451690127;ZNF423:-2.50825688284;NR5A1,2:-2.5316145125;SOX17:-2.81051809799;PBX1:-2.8237568587;PAX5:-2.84440624067;FOX{I1,J2}:-2.84560689051;NRF1:-2.90392398663;GFI1:-2.92367719122;YY1:-2.95224115534;ARID5B:-2.95583080236;AR:-3.03204708775;LHX3,4:-3.47895277897;ZNF143:-3.56623490009;LEF1_TCF7_TCF7L1,2:-3.56988756597 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11870-125B7;search_select_hide=table117:FF:11870-125B7 | |||
}} | }} |
Latest revision as of 18:25, 4 June 2020
Name: | CD14+ monocytes - treated with BCG, donor2 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13475 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13475
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13475
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0831 |
10 | 10 | 0.0227 |
100 | 100 | 0.989 |
101 | 101 | 0.816 |
102 | 102 | 0.803 |
103 | 103 | 0.274 |
104 | 104 | 0.533 |
105 | 105 | 0.152 |
106 | 106 | 7.61515e-4 |
107 | 107 | 0.21 |
108 | 108 | 0.87 |
109 | 109 | 0.248 |
11 | 11 | 0.164 |
110 | 110 | 0.138 |
111 | 111 | 0.0371 |
112 | 112 | 0.38 |
113 | 113 | 0.561 |
114 | 114 | 0.0171 |
115 | 115 | 0.231 |
116 | 116 | 0.873 |
117 | 117 | 0.0723 |
118 | 118 | 0.203 |
119 | 119 | 0.141 |
12 | 12 | 0.347 |
120 | 120 | 0.783 |
121 | 121 | 0.524 |
122 | 122 | 0.556 |
123 | 123 | 0.218 |
124 | 124 | 0.795 |
125 | 125 | 0.387 |
126 | 126 | 0.267 |
127 | 127 | 0.439 |
128 | 128 | 0.0377 |
129 | 129 | 0.41 |
13 | 13 | 0.108 |
130 | 130 | 0.17 |
131 | 131 | 0.771 |
132 | 132 | 0.0624 |
133 | 133 | 0.563 |
134 | 134 | 0.689 |
135 | 135 | 0.633 |
136 | 136 | 0.917 |
137 | 137 | 0.0313 |
138 | 138 | 0.213 |
139 | 139 | 0.0627 |
14 | 14 | 0.439 |
140 | 140 | 0.332 |
141 | 141 | 0.226 |
142 | 142 | 0.0571 |
143 | 143 | 0.0239 |
144 | 144 | 0.655 |
145 | 145 | 0.294 |
146 | 146 | 0.752 |
147 | 147 | 0.595 |
148 | 148 | 0.013 |
149 | 149 | 0.876 |
15 | 15 | 0.166 |
150 | 150 | 0.416 |
151 | 151 | 0.392 |
152 | 152 | 0.243 |
153 | 153 | 0.819 |
154 | 154 | 0.504 |
155 | 155 | 0.911 |
156 | 156 | 0.499 |
157 | 157 | 0.613 |
158 | 158 | 0.0386 |
159 | 159 | 0.504 |
16 | 16 | 0.3 |
160 | 160 | 0.361 |
161 | 161 | 0.456 |
162 | 162 | 0.21 |
163 | 163 | 0.0778 |
164 | 164 | 0.114 |
165 | 165 | 0.137 |
166 | 166 | 0.691 |
167 | 167 | 0.147 |
168 | 168 | 0.219 |
169 | 169 | 0.00733 |
17 | 17 | 0.192 |
18 | 18 | 0.125 |
19 | 19 | 0.453 |
2 | 2 | 0.657 |
20 | 20 | 0.26 |
21 | 21 | 0.567 |
22 | 22 | 0.31 |
23 | 23 | 0.04 |
24 | 24 | 0.322 |
25 | 25 | 0.409 |
26 | 26 | 0.066 |
27 | 27 | 0.762 |
28 | 28 | 0.487 |
29 | 29 | 0.254 |
3 | 3 | 0.11 |
30 | 30 | 0.539 |
31 | 31 | 0.789 |
32 | 32 | 0.803 |
33 | 33 | 0.284 |
34 | 34 | 0.646 |
35 | 35 | 0.183 |
36 | 36 | 0.0816 |
37 | 37 | 0.0714 |
38 | 38 | 0.394 |
39 | 39 | 0.813 |
4 | 4 | 0.921 |
40 | 40 | 0.223 |
41 | 41 | 0.016 |
42 | 42 | 0.369 |
43 | 43 | 0.0308 |
44 | 44 | 0.898 |
45 | 45 | 0.791 |
46 | 46 | 0.183 |
47 | 47 | 0.528 |
48 | 48 | 0.476 |
49 | 49 | 0.133 |
5 | 5 | 0.286 |
50 | 50 | 0.994 |
51 | 51 | 0.419 |
52 | 52 | 0.377 |
53 | 53 | 0.497 |
54 | 54 | 0.371 |
55 | 55 | 0.403 |
56 | 56 | 0.675 |
57 | 57 | 0.778 |
58 | 58 | 0.145 |
59 | 59 | 0.218 |
6 | 6 | 0.877 |
60 | 60 | 0.0463 |
61 | 61 | 0.672 |
62 | 62 | 0.0754 |
63 | 63 | 0.488 |
64 | 64 | 0.439 |
65 | 65 | 0.229 |
66 | 66 | 0.281 |
67 | 67 | 0.547 |
68 | 68 | 0.867 |
69 | 69 | 0.449 |
7 | 7 | 0.265 |
70 | 70 | 0.0381 |
71 | 71 | 0.0379 |
72 | 72 | 0.164 |
73 | 73 | 0.171 |
74 | 74 | 0.11 |
75 | 75 | 0.131 |
76 | 76 | 0.192 |
77 | 77 | 0.511 |
78 | 78 | 0.111 |
79 | 79 | 0.401 |
8 | 8 | 0.357 |
80 | 80 | 0.215 |
81 | 81 | 0.331 |
82 | 82 | 0.189 |
83 | 83 | 0.0255 |
84 | 84 | 0.226 |
85 | 85 | 0.0206 |
86 | 86 | 0.052 |
87 | 87 | 0.658 |
88 | 88 | 0.619 |
89 | 89 | 0.233 |
9 | 9 | 0.362 |
90 | 90 | 0.0926 |
91 | 91 | 0.296 |
92 | 92 | 0.273 |
93 | 93 | 0.387 |
94 | 94 | 0.0802 |
95 | 95 | 0.363 |
96 | 96 | 0.45 |
97 | 97 | 0.66 |
98 | 98 | 0.101 |
99 | 99 | 0.0761 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13475
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0011103 human CD14-positive monocytes - treated with BCG sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000766 (myeloid leukocyte)
0000219 (motile cell)
0000325 (stuff accumulating cell)
0000473 (defensive cell)
0000234 (phagocyte)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0000255 (eukaryotic cell)
0000576 (monocyte)
0000860 (classical monocyte)
0002057 (CD14-positive, CD16-negative classical monocyte)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
0000625 (experimental infection sample)
0000350 (experimentally modified sample)
0000628 (Bacillus Calmette-Guerin treatment sample)
0011103 (human CD14-positive monocytes - treated with BCG sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)
CL:0002057 (CD14-positive, CD16-negative classical monocyte)