FF:11878-125C6: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005082 | ||
| | |accession_numbers=CAGE;DRX008142;DRR009014;DRZ000439;DRZ001824;DRZ011789;DRZ013174 | ||
| | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000766,CL:0000219,CL:0000325,CL:0000473,CL:0000234,CL:0000738,CL:0002087,CL:0000255,CL:0000576,CL:0000860,CL:0002057 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001,FF:0000625,FF:0000350,FF:0000635,FF:0011104 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr2:68592406..68592424,+!p1@PLEK!3.51!3219.03!PLEK;;chr11:47400078..47400106,-!p1@SPI1!2.69!486.05!SPI1;;chr16:85932760..85932775,+!p1@IRF8!2.60!400.85!IRF8;;chr7:115670804..115670825,-!p1@TFEC!2.53!336.94!TFEC;;chr10:64018918..64018936,+!p2@ZNF365!2.34!217.53!ZNF365;;chr3:101546827..101546847,+!p2@NFKBIZ!2.24!238.18!NFKBIZ;;chr12:54778471..54778528,-!p1@ZNF385A!2.22!163.31!ZNF385A;;chr9:102584159..102584174,+!p2@NR4A3!2.20!273.69!NR4A3;;chr14:35872453..35872485,-!p2@NFKBIA!2.18!353.73!NFKBIA;;chr2:157189180..157189290,-!p1@NR4A2!2.13!655.81!NR4A2;;chr12:72056800..72056834,+!p1@THAP2!2.13!177.51!THAP2;;chr11:47399947..47399961,-!p3@SPI1!2.12!129.74!SPI1;;chr6:106534192..106534224,+!p1@PRDM1!2.10!341.46!PRDM1;;chr19:45971246..45971265,+!p1@FOSB!2.09!2119.13!FOSB;;chr10:35484053..35484076,+!p1@CREM!2.08!284.66!CREM;;chr10:64576105..64576133,-!p1@EGR2!2.08!239.47!EGR2;;chr14:35873947..35873965,-!p1@NFKBIA!2.05!6476.79!NFKBIA;;chr9:102584262..102584276,+!p1@NR4A3!2.05!238.83!NR4A3;;chr11:47400062..47400077,-!p2@SPI1!2.04!107.80!SPI1;;chr20:39317868..39317884,-!p1@MAFB!2.02!1156.06!MAFB;;chr3:101568349..101568365,+!p1@NFKBIZ!2.01!4923.11!NFKBIZ;;chr12:52445218..52445237,+!p1@NR4A1!1.99!1154.77!NR4A1;;chr16:31885093..31885165,+!p1@ZNF267!1.97!1310.33!ZNF267;;chr2:70142232..70142251,+!p1@MXD1!1.93!444.09!MXD1;;chr11:47399996..47400014,-!p4@SPI1!1.93!83.27!SPI1;;chr21:34442439..34442455,+!p1@OLIG1!1.91!80.04!OLIG1;;chr2:61108695..61108753,+!p1@REL!1.89!493.80!REL;;chr2:68592394..68592405,+!p2@PLEK!1.89!76.81!PLEK;;chr4:103422499..103422632,+!p1@NFKB1!1.87!1435.56!NFKB1;;chr19:54041669..54041697,+!p2@ZNF331!1.87!73.59!ZNF331;;chr8:22550982..22550999,-!p1@EGR3!1.84!184.61!EGR3;;chr19:54058073..54058088,+!p1@ZNF331!1.82!64.55!ZNF331;;chr19:36391434..36391450,-!p1@NFKBID!1.81!122.00!NFKBID;;chr2:192015701..192015743,-!p1@STAT4!1.81!85.20!STAT4;;chr11:47400032..47400043,-!p5@SPI1!1.81!63.26!SPI1;;chr10:51572408..51572454,+!p3@NCOA4!1.79!338.23!NCOA4;;chr6:106534230..106534254,+!p2@PRDM1!1.78!142.65!PRDM1;;chr12:72056749..72056767,+!p6@THAP2!1.78!65.19!THAP2;;chr9:102584128..102584144,+!p3@NR4A3!1.75!101.99!NR4A3;;chr10:31288398..31288455,-!p2@ZNF438!1.75!64.55!ZNF438;;chr22:38597987..38598021,+!p2@MAFF!1.74!311.77!MAFF;;chr20:48599506..48599526,+!p1@SNAI1!1.73!323.39!SNAI1;;chr10:31288370..31288393,-!p3@ZNF438!1.72!50.99!ZNF438;;chr1:212782094..212782109,+!p1@ATF3!1.66!1150.90!ATF3;;chr2:145277640..145277771,-!p1@ZEB2!1.66!564.15!ZEB2;;chr10:104155480..104155534,+!p2@NFKB2!1.66!278.20!NFKB2;;chr12:72056773..72056796,+!p3@THAP2!1.66!57.45!THAP2;;chr2:68615063..68615089,+!p4@PLEK!1.66!44.54!PLEK;;chr8:123793988..123794016,+!p1@ZHX2!1.65!74.88!ZHX2;;chr9:102584241..102584261,+!p4@NR4A3!1.65!66.48!NR4A3;;chr12:54778351..54778378,-!p6@ZNF385A!1.65!43.89!ZNF385A;;chrX:153305787..153305807,-!p3@MECP2!1.64!42.60!MECP2;;chr1:37940170..37940190,+!p1@ZC3H12A!1.63!481.53!ZC3H12A;;chr6:391743..391759,+!p1@IRF4!1.63!41.96!IRF4;;chr2:145275162..145275202,-!p2@ZEB2!1.62!227.21!ZEB2;;chr4:83822199..83822239,+!p2@THAP9!1.62!47.77!THAP9;;chr10:51572339..51572376,+!p4@NCOA4!1.61!87.14!NCOA4;;chr14:35872962..35873025,-!p3@NFKBIA!1.59!92.30!NFKBIA;;chr1:25256756..25256774,-!p1@RUNX3!1.59!69.71!RUNX3;;chr6:144385698..144385742,-!p2@PLAGL1!1.59!45.83!PLAGL1;;chr9:129567282..129567353,+!p1@ZBTB43!1.57!453.13!ZBTB43;;chr21:30671235..30671253,+!p1@BACH1!1.57!435.70!BACH1;;chr6:12012170..12012245,+!p1@HIVEP1!1.56!170.41!HIVEP1;;chr14:35872494..35872511,-!p5@NFKBIA!1.56!46.47!NFKBIA;;chr7:50344289..50344323,+!p1@IKZF1!1.56!35.50!IKZF1;;chrX:153305962..153305995,-!p5@MECP2!1.56!35.50!MECP2;;chr10:35484090..35484104,+!p6@CREM!1.55!34.86!CREM;;chr4:106068026..106068084,+!p1@TET2!1.52!278.20!TET2;;chr13:41593425..41593480,-!p1@ELF1!1.50!188.48!ELF1;;chr21:30671690..30671762,+!p2@BACH1!1.50!101.99!BACH1;;chr5:142782823..142782854,-!p3@NR3C1!1.50!43.25!NR3C1;;chrX:129244454..129244488,-!p1@ELF4!1.49!205.26!ELF4;;chr10:104154246..104154347,+!p3@NFKB2!1.49!178.15!NFKB2;;chr21:40177845..40177863,+!p1@ETS2!1.48!1644.69!ETS2;;chr18:77155922..77155939,+!p1@NFATC1!1.48!77.46!NFATC1;;chr2:61108808..61108821,+!p3@REL!1.48!36.79!REL;;chr2:68615031..68615055,+!p3@PLEK!1.48!29.05!PLEK;;chr19:47616992..47617011,-!p4@ZC3H4!1.47!59.38!ZC3H4;;chr6:12012249..12012266,+!p5@HIVEP1!1.47!48.41!HIVEP1;;chr4:103423079..103423112,+!p4@NFKB1!1.47!28.40!NFKB1;;chr6:15246200..15246214,+!p2@JARID2!1.46!75.52!JARID2;;chr18:3448455..3448480,+!p5@TGIF1!1.46!50.35!TGIF1;;chr14:35872926..35872951,-!p4@NFKBIA!1.45!38.08!NFKBIA;;chr13:41593392..41593403,-!p7@ELF1!1.44!26.46!ELF1;;chr8:53373491..53373506,-!p4@ST18!1.44!26.46!ST18;;chr10:3827371..3827386,-!p2@KLF6!1.43!211.72!KLF6;;chr1:161736038..161736056,+!p4@ATF6!1.43!59.38!ATF6;;chr19:50432132..50432217,+!p2@ATF5!1.43!30.98!ATF5;;chr2:191885737..191885750,-!p4@STAT1!1.41!24.53!STAT1;;chr2:97202480..97202499,+!p1@ARID5A!1.40!233.02!ARID5A;;chr10:35484804..35484902,+!p2@CREM!1.40!89.08!CREM;;chr3:150126101..150126118,+!p6@TSC22D2!1.40!39.37!TSC22D2;;chr7:106809470..106809481,+!p2@HBP1!1.40!33.57!HBP1;;chr21:30673091..30673135,+!p7@BACH1!1.40!23.88!BACH1;;chr2:28618532..28618610,+!p4@FOSL2!1.39!40.02!FOSL2;;chr1:38325227..38325246,-!p2@MTF1!1.38!30.98!MTF1;;chr9:102584278..102584285,+!p5@NR4A3!1.38!23.24!NR4A3;;chr1:157108130..157108173,-!p1@ETV3!1.37!158.14!ETV3;;chr3:12329397..12329433,+!p2@PPARG!1.37!49.70!PPARG;;chr20:48809000..48809053,+!p12@CEBPB!1.37!29.69!CEBPB;;chr2:157189617..157189667,-!p4@NR4A2!1.37!22.59!NR4A2;;chr20:48807351..48807384,+!p1@CEBPB!1.36!2155.92!CEBPB;;chr9:110252035..110252057,-!p1@KLF4!1.36!338.23!KLF4;;chr6:44233252..44233296,-!p1@NFKBIE!1.36!206.56!NFKBIE;;chr3:39195037..39195069,-!p2@CSRNP1!1.36!133.62!CSRNP1;;chr8:80679993..80680011,-!p1@HEY1!1.36!31.63!HEY1;;chr4:103446513..103446530,+!p19@NFKB1!1.36!21.95!NFKB1;;chr17:38497662..38497713,+!p4@RARA!1.35!24.53!RARA;;chr2:145271342..145271377,-!p5@ZEB2!1.35!21.30!ZEB2;;chr6:12011943..12012015,+!p2@HIVEP1!1.34!66.48!HIVEP1;;chr19:45251395..45251432,+!p8@BCL3!1.34!20.66!BCL3;;chr21:30672433..30672464,+!p6@BACH1!1.34!20.66!BACH1;;chr2:28615716..28615733,+!p1@FOSL2!1.33!920.46!FOSL2;;chr11:65430554..65430579,-!p3@RELA!1.33!51.64!RELA;;chr2:61108771..61108789,+!p4@REL!1.33!30.34!REL;;chr12:52431016..52431071,+!p4@NR4A1!1.33!23.88!NR4A1;;chr3:5020939..5020952,+!p2@BHLHE40!1.32!61.97!BHLHE40;;chr21:36260295..36260310,-!p3@RUNX1!1.32!31.63!RUNX1;;chr10:35416142..35416169,+!p3@CREM!1.31!50.35!CREM;;chr19:19496539..19496576,+!p8@GATAD2A!1.31!33.57!GATAD2A;;chr18:3449618..3449634,+!p13@TGIF1!1.31!23.88!TGIF1;;chr4:106066776..106066791,+!p9@TET2!1.31!19.36!TET2;;chr11:47400045..47400060,-!p6@SPI1!1.31!19.36!SPI1;;chr8:81397820..81397836,+!p2@ZBTB10!1.30!23.88!ZBTB10;;chr4:83821967..83821998,+!p3@THAP9!1.30!23.24!THAP9;;chr2:238600998..238601013,+!p5@LRRFIP1!1.29!18.72!LRRFIP1;;chr12:11802753..11802834,+!p2@ETV6!1.28!86.49!ETV6;;chr12:96588368..96588394,+!p3@ELK3!1.28!48.41!ELK3;;chr18:3449527..3449582,+!p6@TGIF1!1.28!34.21!TGIF1;;chr2:8822176..8822196,+!p1@ID2!1.27!2410.89!ID2;;chr21:40177892..40177903,+!p2@ETS2!1.27!69.71!ETS2;;chr3:12330560..12330579,+!p1@PPARG!1.27!20.01!PPARG;;chr19:36389729..36389751,-!p3@NFKBID!1.27!17.43!NFKBID;;chr5:88178983..88179012,-!p1@MEF2C!1.26!131.03!MEF2C;;chr14:75745523..75745537,+!p1@FOS!1.25!1971.96!FOS;;chr12:96588219..96588263,+!p2@ELK3!1.25!117.48!ELK3;;chr19:45252008..45252024,+!p2@BCL3!1.25!54.87!BCL3;;chr14:35872414..35872425,-!p7@NFKBIA!1.25!18.72!NFKBIA;;chr1:212738742..212738755,+!p2@ATF3!1.25!16.78!ATF3;;chr6:106535598..106535637,+!p7@PRDM1!1.25!16.78!PRDM1;;chr6:28048343..28048354,+!p1@ZNF165!1.25!16.78!ZNF165;;chr2:113999360..113999386,-!p4@PAX8!1.25!16.78!PAX8;;chr3:170075436..170075520,+!p1@SKIL!1.24!343.40!SKIL;;chr7:17338266..17338282,+!p1@AHR!1.23!171.05!AHR;;chr2:238600933..238600985,+!p3@LRRFIP1!1.23!84.56!LRRFIP1;;chr4:83822294..83822306,+!p8@THAP9!1.23!16.14!THAP9;;chr11:47399920..47399931,-!p7@SPI1!1.23!16.14!SPI1;;chrX:129244430..129244442,-!p5@ELF4!1.23!16.14!ELF4;;chr7:115670792..115670797,-!p2@TFEC!1.23!16.14!TFEC;;chr21:34398234..34398250,+!p1@OLIG2!1.23!16.14!OLIG2;;chr7:149470641..149470694,-!p1@ZNF467!1.22!69.07!ZNF467;;chr4:106066712..106066728,+!p8@TET2!1.22!15.49!TET2;;chr19:54041574..54041589,+!p6@ZNF331!1.22!15.49!ZNF331;;chr1:935467..935484,-!p1@HES4!1.21!66.48!HES4;;chr17:79885537..79885554,-!p2@MAFG!1.21!29.05!MAFG;;chr3:193853927..193853944,+!p1@HES1!1.20!473.14!HES1;;chr21:36421535..36421610,-!p2@RUNX1!1.20!52.28!RUNX1;;chr18:3449586..3449617,+!p8@TGIF1!1.20!23.88!TGIF1;;chr10:31288329..31288353,-!p7@ZNF438!1.20!14.85!ZNF438;;chr12:72056706..72056717,+!p10@THAP2!1.20!14.85!THAP2;;chr10:104155455..104155479,+!p1@NFKB2!1.18!203.97!NFKB2;;chr9:94186101..94186122,-!p1@NFIL3!1.18!196.23!NFIL3;;chr22:38598086..38598105,+!p1@MAFF!1.18!148.46!MAFF;;chr19:36389839..36389857,-!p4@NFKBID!1.18!14.20!NFKBID;;chr12:48298765..48298783,-!p2@VDR!1.17!29.05!VDR;;chr3:5021026..5021035,+!p5@BHLHE40!1.16!16.78!BHLHE40;;chr4:106066730..106066754,+!p6@TET2!1.16!13.56!TET2;;chrX:153305741..153305753,-!p4@MECP2!1.16!13.56!MECP2;;chr17:38497715..38497734,+!p8@RARA!1.16!13.56!RARA;;chr19:45971060..45971122,+!p3@FOSB!1.16!13.56!FOSB;;chr11:615942..615957,-!p1@IRF7!1.15!123.93!IRF7;;chr2:70314240..70314256,+!p4@PCBP1!1.15!27.11!PCBP1;;chr2:185463247..185463263,+!p1@ZNF804A!1.14!22.59!ZNF804A;;chr2:145277882..145277967,-!p3@ZEB2!1.14!21.95!ZEB2;;chr10:104155659..104155676,+!p4@NFKB2!1.14!16.14!NFKB2;;chr1:25256439..25256476,-!p3@RUNX3!1.14!12.91!RUNX3;;chr1:156470515..156470542,-!p2@MEF2D!1.13!65.84!MEF2D;;chr7:17338324..17338341,+!p3@AHR!1.13!41.96!AHR;;chr17:40440225..40440268,+!p3@STAT5A!1.13!16.14!STAT5A;;chr2:157198916..157198978,-!p2@NR4A2!1.12!42.60!NR4A2;;chr3:39195139..39195150,-!p3@CSRNP1!1.12!15.49!CSRNP1;;chr2:61108878..61108891,+!p5@REL!1.12!12.26!REL;;chr10:3827389..3827408,-!p1@KLF6!1.11!912.07!KLF6;;chr17:38474489..38474548,+!p1@RARA!1.11!375.03!RARA;;chr7:28725740..28725778,+!p1@C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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000222;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000234;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000576;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000763;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000766;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000860;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002193;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002390;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002405 | |||
|ffid_belonging_in_development=CL:0000049,CL:0000134,CL:0002057 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 41: | ||
|fonse_treatment=FF:0000625,FF:0000635,FF:0011104,FF:11878-125C6 | |fonse_treatment=FF:0000625,FF:0000635,FF:0011104,FF:11878-125C6 | ||
|fonse_treatment_closure=FF:0000625,FF:0000635,FF:0011104,FF:11878-125C6 | |fonse_treatment_closure=FF:0000625,FF:0000635,FF:0011104,FF:11878-125C6 | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Candida%252c%2520donor2.CNhs13488.11878-125C6.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Candida%252c%2520donor2.CNhs13488.11878-125C6.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Candida%252c%2520donor2.CNhs13488.11878-125C6.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Candida%252c%2520donor2.CNhs13488.11878-125C6.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Candida%252c%2520donor2.CNhs13488.11878-125C6.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11878-125C6 | |||
|is_a=EFO:0002091;;FF:0011104 | |||
|is_obsolete= | |||
|library_id=CNhs13488 | |||
|library_id_phase_based=2:CNhs13488 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11878 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11878 | |||
|name=CD14+ monocytes - treated with Candida, donor2 | |||
|namespace= | |namespace= | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs13488,LSID1025,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0.343894110535045,0,0,0,0.216293844171574,0.199701252137059,0,0.595076592854575,0.57176819639822,0,0.216293844171574,0,0,0,0,0,0,0,0.467823209448954,0.467823209448954,0,0,0.0629708338231468,0,0,0,0.394926998409861,0,0.369865313180896,0,1.33166401941416,0.493119159080772,0,0,0,0.216293844171574,0,0,0,1.33556841356363,0,0.360019282223445,0,0,0.0547076222904415,0.216293844171574,0,0,0,0.470900173112065,0,0,0,-0.0242150211128343,0,0,0,0.216293844171574,0,-0.0556580286538629,0.216293844171574,0.119301482928969,0,0.467823209448954,-0.097343627213097,0,1.3795858411821,0,0,0,0.216293844171574,0,0,0,0,0.554118153381339,0,0,0.741812609213978,0,0,0,0.0330306855444763,0,0,0,0.0422155688369714,0,0,-0.481402122341008,0.108146922085787,0,0,-0.0584468268118252,0.289599920209701,0.180009641111722,0,1.19910640627079,0,0.118258492933868,0.508775558356669,0,0,0.108146922085787,0,0,1.21268085775132,0.216293844171574,0,0,0,0,0,0.192661513196669,0,0,0,0,-0.096373593922461,0,0,0,0.33081922965131,0.18769079562776,0,1.4870293700791,0.216293844171574,0,0,0 | |||
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| |||
|rna_box=125 | |||
|rna_catalog_number= | |||
|rna_concentration=0.73057 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number=D4-9 | |||
|rna_od260/230=1.59 | |||
|rna_od260/280=2.03 | |||
|rna_position=C6 | |||
|rna_rin=8.4 | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=125C6 | |||
|rna_weight_ug=3.287565 | |||
|sample_age=51 | |||
|sample_category=primary cells | |||
|sample_cell_catalog= | |||
|sample_cell_line= | |||
|sample_cell_lot= | |||
|sample_cell_type=monocyte | |||
|sample_collaboration=Christine Wells (University of Queensland) | |||
|sample_company= | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease= | |||
|sample_donor(cell lot)=donor2 | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;2.30031292345946e-277!GO:0005737;cytoplasm;8.49774198750517e-123!GO:0043227;membrane-bound organelle;2.31500131072196e-112!GO:0043231;intracellular membrane-bound organelle;3.94984139852012e-112!GO:0043226;organelle;2.39267330919914e-105!GO:0043229;intracellular organelle;1.05414546010681e-104!GO:0044444;cytoplasmic part;3.21637689528008e-76!GO:0005515;protein binding;8.42389032005206e-75!GO:0044422;organelle part;3.37352164524744e-68!GO:0044446;intracellular organelle part;9.63037582032084e-67!GO:0044237;cellular metabolic process;3.34915526147784e-65!GO:0044238;primary metabolic process;1.9401616898963e-64!GO:0043170;macromolecule metabolic process;1.45828643095161e-61!GO:0032991;macromolecular complex;2.39655293812109e-58!GO:0003723;RNA binding;2.65982722504166e-53!GO:0030529;ribonucleoprotein complex;7.88751258509895e-50!GO:0044428;nuclear part;4.52707633454704e-48!GO:0005634;nucleus;8.50701662077644e-48!GO:0019538;protein metabolic process;4.78381398490702e-46!GO:0044267;cellular protein metabolic process;1.49937565930794e-42!GO:0044260;cellular macromolecule metabolic process;2.03498240134269e-42!GO:0006412;translation;8.36691562517272e-40!GO:0033036;macromolecule localization;1.41354582782441e-39!GO:0015031;protein transport;1.14257518274849e-38!GO:0045184;establishment of protein localization;1.50932802544763e-38!GO:0043233;organelle lumen;7.99889382574472e-38!GO:0031974;membrane-enclosed lumen;7.99889382574472e-38!GO:0008104;protein localization;1.34726499397356e-36!GO:0006915;apoptosis;1.6473995177305e-34!GO:0012501;programmed cell death;1.95595882415396e-34!GO:0005829;cytosol;1.11679765428288e-33!GO:0043283;biopolymer metabolic process;1.21153068847702e-33!GO:0008219;cell death;4.78591884890099e-33!GO:0016265;death;4.78591884890099e-33!GO:0010467;gene expression;1.18165751680612e-32!GO:0016071;mRNA metabolic process;2.54002449033473e-30!GO:0006396;RNA processing;2.81863443144063e-30!GO:0031090;organelle membrane;3.15038592149277e-30!GO:0009059;macromolecule biosynthetic process;5.20477480873996e-30!GO:0031981;nuclear lumen;5.40485745151813e-30!GO:0043234;protein complex;6.09838142987699e-30!GO:0016043;cellular component organization and biogenesis;3.4198176794605e-29!GO:0009058;biosynthetic process;4.76596274881818e-29!GO:0044249;cellular biosynthetic process;1.62290501785896e-28!GO:0008380;RNA splicing;9.23756710045178e-27!GO:0046907;intracellular transport;1.10070725444545e-26!GO:0006886;intracellular protein transport;7.28051488656664e-26!GO:0005840;ribosome;1.90285486974284e-25!GO:0006397;mRNA processing;3.80113758320829e-25!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;5.08834818781573e-24!GO:0005739;mitochondrion;1.32472254938506e-23!GO:0003735;structural constituent of ribosome;3.22243566507091e-23!GO:0033279;ribosomal subunit;3.59626368345876e-23!GO:0031967;organelle envelope;3.88488281104893e-23!GO:0005830;cytosolic ribosome (sensu Eukaryota);5.37935099472824e-23!GO:0042981;regulation of apoptosis;6.46868828037407e-23!GO:0031975;envelope;6.67578963888302e-23!GO:0043067;regulation of programmed cell death;1.55223333728843e-22!GO:0008134;transcription factor binding;2.72321997347956e-22!GO:0065003;macromolecular complex assembly;5.84643575464325e-22!GO:0044445;cytosolic part;4.58139568488971e-21!GO:0005654;nucleoplasm;5.88400633486619e-21!GO:0000166;nucleotide binding;9.45767040488904e-21!GO:0005681;spliceosome;1.29153655186319e-20!GO:0051649;establishment of cellular localization;3.6733735061486e-20!GO:0051641;cellular localization;1.66584809127597e-19!GO:0007243;protein kinase cascade;2.57304214782885e-19!GO:0022607;cellular component assembly;9.00181643991534e-19!GO:0002376;immune system process;1.15960470297867e-18!GO:0048523;negative regulation of cellular process;1.64196508756134e-18!GO:0022613;ribonucleoprotein complex biogenesis and assembly;2.17544829786806e-18!GO:0044429;mitochondrial part;4.9881314478075e-18!GO:0044451;nucleoplasm part;1.88415604106425e-17!GO:0016192;vesicle-mediated transport;6.09867297529141e-17!GO:0048770;pigment granule;6.31481627236976e-17!GO:0042470;melanosome;6.31481627236976e-17!GO:0007242;intracellular signaling cascade;1.39479952873772e-16!GO:0048519;negative regulation of biological process;1.4365671568122e-16!GO:0044265;cellular macromolecule catabolic process;3.9799878216624e-16!GO:0006512;ubiquitin cycle;4.2195738691053e-16!GO:0017111;nucleoside-triphosphatase activity;4.89902238612807e-16!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;5.05086033012298e-16!GO:0016462;pyrophosphatase activity;5.05086033012298e-16!GO:0043412;biopolymer modification;5.05086033012298e-16!GO:0016817;hydrolase activity, acting on acid anhydrides;5.65407954337831e-16!GO:0050794;regulation of cellular process;6.66179671920901e-16!GO:0007249;I-kappaB kinase/NF-kappaB cascade;2.19297875558991e-15!GO:0006119;oxidative phosphorylation;2.91602056337934e-15!GO:0043285;biopolymer catabolic process;2.91602056337934e-15!GO:0022618;protein-RNA complex assembly;4.22237338335847e-15!GO:0043069;negative regulation of programmed cell death;5.14694282002847e-15!GO:0043066;negative regulation of apoptosis;5.41898736981605e-15!GO:0032553;ribonucleotide binding;5.48330860460149e-15!GO:0032555;purine ribonucleotide binding;5.48330860460149e-15!GO:0005773;vacuole;6.34914002528304e-15!GO:0065009;regulation of a molecular function;6.65903161836136e-15!GO:0006464;protein modification process;9.04829964598313e-15!GO:0006996;organelle organization and biogenesis;2.62560656079705e-14!GO:0006955;immune response;2.77663152331789e-14!GO:0043687;post-translational protein modification;2.86342424980463e-14!GO:0017076;purine nucleotide binding;3.08777397028069e-14!GO:0016070;RNA metabolic process;4.88777820000818e-14!GO:0006366;transcription from RNA polymerase II promoter;5.07080719162068e-14!GO:0006605;protein targeting;5.57125185492092e-14!GO:0005740;mitochondrial envelope;5.7960701208016e-14!GO:0019941;modification-dependent protein catabolic process;5.96063166919669e-14!GO:0043632;modification-dependent macromolecule catabolic process;5.96063166919669e-14!GO:0006950;response to stress;6.14178412539268e-14!GO:0003712;transcription cofactor activity;7.13703176130956e-14!GO:0044257;cellular protein catabolic process;7.52431306591332e-14!GO:0051603;proteolysis involved in cellular protein catabolic process;7.83202728212116e-14!GO:0006511;ubiquitin-dependent protein catabolic process;8.98600124104734e-14!GO:0006913;nucleocytoplasmic transport;9.63578240520043e-14!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;9.8942472441243e-14!GO:0009057;macromolecule catabolic process;1.19668324127563e-13!GO:0051169;nuclear transport;1.92297416534337e-13!GO:0031966;mitochondrial membrane;1.92297416534337e-13!GO:0003676;nucleic acid binding;2.18265849225043e-13!GO:0000323;lytic vacuole;2.78360883748029e-13!GO:0005764;lysosome;2.78360883748029e-13!GO:0019866;organelle inner membrane;2.8188773479245e-13!GO:0051246;regulation of protein metabolic process;2.8333311328447e-13!GO:0050789;regulation of biological process;4.78652763421572e-13!GO:0016604;nuclear body;7.77678329843233e-13!GO:0048522;positive regulation of cellular process;1.11830812300884e-12!GO:0015935;small ribosomal subunit;1.31395950548375e-12!GO:0008135;translation factor activity, nucleic acid binding;1.58716449926691e-12!GO:0030163;protein catabolic process;2.40570851886138e-12!GO:0006916;anti-apoptosis;2.40570851886138e-12!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;3.20575802867749e-12!GO:0065007;biological regulation;3.47505040010788e-12!GO:0044248;cellular catabolic process;3.69761472045732e-12!GO:0016874;ligase activity;5.61114322694208e-12!GO:0048518;positive regulation of biological process;6.17235645882278e-12!GO:0006793;phosphorus metabolic process;6.36920276629597e-12!GO:0006796;phosphate metabolic process;6.36920276629597e-12!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);6.99500843712718e-12!GO:0006259;DNA metabolic process;8.22514175539865e-12!GO:0015934;large ribosomal subunit;9.74559762526124e-12!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.2193891405733e-11!GO:0012505;endomembrane system;1.349399023476e-11!GO:0005768;endosome;1.43467478927963e-11!GO:0016607;nuclear speck;1.47293690866662e-11!GO:0006457;protein folding;1.54669979987959e-11!GO:0003743;translation initiation factor activity;2.77317430847986e-11!GO:0006413;translational initiation;4.25599262265922e-11!GO:0050790;regulation of catalytic activity;5.6889234277263e-11!GO:0005794;Golgi apparatus;1.07840223084989e-10!GO:0016310;phosphorylation;1.09234300823208e-10!GO:0006446;regulation of translational initiation;1.17516114427504e-10!GO:0005743;mitochondrial inner membrane;1.27050489411377e-10!GO:0005524;ATP binding;1.48860824400237e-10!GO:0006417;regulation of translation;1.6749755790132e-10!GO:0000502;proteasome complex (sensu Eukaryota);1.84104906950755e-10!GO:0032559;adenyl ribonucleotide binding;2.14289122309312e-10!GO:0009615;response to virus;2.58776138055786e-10!GO:0051186;cofactor metabolic process;2.7998823421443e-10!GO:0031324;negative regulation of cellular metabolic process;3.57315781594584e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;4.75842391803095e-10!GO:0009967;positive regulation of signal transduction;6.25172442274476e-10!GO:0044455;mitochondrial membrane part;1.10243564351882e-09!GO:0030554;adenyl nucleotide binding;1.16684234933789e-09!GO:0009889;regulation of biosynthetic process;1.19211191393891e-09!GO:0051082;unfolded protein binding;1.21861083983969e-09!GO:0048468;cell development;1.27247345516111e-09!GO:0005730;nucleolus;1.50280484978712e-09!GO:0005635;nuclear envelope;1.50780508752529e-09!GO:0019829;cation-transporting ATPase activity;1.5692419577825e-09!GO:0006732;coenzyme metabolic process;2.31570502943072e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;2.57561132757819e-09!GO:0015986;ATP synthesis coupled proton transport;2.83237479747192e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;2.83237479747192e-09!GO:0031326;regulation of cellular biosynthetic process;3.49883778263352e-09!GO:0005770;late endosome;3.74718924696796e-09!GO:0043065;positive regulation of apoptosis;3.74718924696796e-09!GO:0007049;cell cycle;3.80666129032001e-09!GO:0009607;response to biotic stimulus;5.54004645050577e-09!GO:0043068;positive regulation of programmed cell death;5.62135521161144e-09!GO:0016787;hydrolase activity;6.52973744352102e-09!GO:0051170;nuclear import;6.52973744352102e-09!GO:0051726;regulation of cell cycle;7.15455468002043e-09!GO:0017038;protein import;7.17270506566105e-09!GO:0000074;regulation of progression through cell cycle;8.138727836314e-09!GO:0000398;nuclear mRNA splicing, via spliceosome;8.21994910084273e-09!GO:0000375;RNA splicing, via transesterification reactions;8.21994910084273e-09!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;8.21994910084273e-09!GO:0008639;small protein conjugating enzyme activity;8.84910054391118e-09!GO:0019787;small conjugating protein ligase activity;8.9411316191732e-09!GO:0009892;negative regulation of metabolic process;1.23153184936035e-08!GO:0004842;ubiquitin-protein ligase activity;1.25355097437627e-08!GO:0009152;purine ribonucleotide biosynthetic process;1.25355097437627e-08!GO:0006164;purine nucleotide biosynthetic process;1.26324786670719e-08!GO:0006163;purine nucleotide metabolic process;1.33661110070415e-08!GO:0006606;protein import into nucleus;1.389838182012e-08!GO:0009150;purine ribonucleotide metabolic process;1.46036564288855e-08!GO:0019899;enzyme binding;1.51969413396608e-08!GO:0005783;endoplasmic reticulum;1.51969413396608e-08!GO:0003713;transcription coactivator activity;1.53040863849404e-08!GO:0009056;catabolic process;1.77525322699016e-08!GO:0042623;ATPase activity, coupled;1.78457128959679e-08!GO:0016564;transcription repressor activity;1.80841353899068e-08!GO:0016887;ATPase activity;2.40061370337462e-08!GO:0009259;ribonucleotide metabolic process;2.69319092620032e-08!GO:0006754;ATP biosynthetic process;3.55186427090483e-08!GO:0006753;nucleoside phosphate metabolic process;3.55186427090483e-08!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;4.78289899655931e-08!GO:0009260;ribonucleotide biosynthetic process;4.93743571157445e-08!GO:0019222;regulation of metabolic process;5.2179751379743e-08!GO:0031965;nuclear membrane;6.09655381860581e-08!GO:0043228;non-membrane-bound organelle;6.75774221926184e-08!GO:0043232;intracellular non-membrane-bound organelle;6.75774221926184e-08!GO:0048193;Golgi vesicle transport;7.49152419730881e-08!GO:0016469;proton-transporting two-sector ATPase complex;7.50330266515485e-08!GO:0005774;vacuolar membrane;8.97887267216975e-08!GO:0005746;mitochondrial respiratory chain;1.082349406038e-07!GO:0044453;nuclear membrane part;1.0826335124579e-07!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.14196277512605e-07!GO:0045786;negative regulation of progression through cell cycle;1.14279388802107e-07!GO:0016563;transcription activator activity;1.1973989505137e-07!GO:0016568;chromatin modification;1.21350972439106e-07!GO:0003924;GTPase activity;1.31909083840672e-07!GO:0015078;hydrogen ion transmembrane transporter activity;1.41845195463018e-07!GO:0006917;induction of apoptosis;1.43645211551063e-07!GO:0006461;protein complex assembly;1.55249264533408e-07!GO:0009966;regulation of signal transduction;1.59366014285533e-07!GO:0016881;acid-amino acid ligase activity;1.74684598522004e-07!GO:0046034;ATP metabolic process;1.82518069118239e-07!GO:0007264;small GTPase mediated signal transduction;1.94974526135005e-07!GO:0016481;negative regulation of transcription;1.99433375723583e-07!GO:0008047;enzyme activator activity;2.02149836754175e-07!GO:0004386;helicase activity;2.13139780771846e-07!GO:0012502;induction of programmed cell death;2.32003844774638e-07!GO:0008565;protein transporter activity;2.57336174924244e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.73466319980769e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.73466319980769e-07!GO:0045321;leukocyte activation;2.73791407332234e-07!GO:0009142;nucleoside triphosphate biosynthetic process;3.23700441746716e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;3.23700441746716e-07!GO:0005525;GTP binding;3.6544124821419e-07!GO:0006325;establishment and/or maintenance of chromatin architecture;3.66055930512814e-07!GO:0051188;cofactor biosynthetic process;3.88686693281576e-07!GO:0044437;vacuolar part;4.00074903085983e-07!GO:0009108;coenzyme biosynthetic process;4.87436894515435e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;6.35526711466694e-07!GO:0009144;purine nucleoside triphosphate metabolic process;6.35526711466694e-07!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;6.6776645731566e-07!GO:0009199;ribonucleoside triphosphate metabolic process;7.19531383960016e-07!GO:0050136;NADH dehydrogenase (quinone) activity;7.27403751820853e-07!GO:0003954;NADH dehydrogenase activity;7.27403751820853e-07!GO:0008137;NADH dehydrogenase (ubiquinone) activity;7.27403751820853e-07!GO:0005765;lysosomal membrane;8.04357938162788e-07!GO:0006357;regulation of transcription from RNA polymerase II promoter;8.20769617109397e-07!GO:0008026;ATP-dependent helicase activity;8.31678117703705e-07!GO:0006323;DNA packaging;9.3292017499265e-07!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;9.70815516834808e-07!GO:0050657;nucleic acid transport;9.70815516834808e-07!GO:0051236;establishment of RNA localization;9.70815516834808e-07!GO:0050658;RNA transport;9.70815516834808e-07!GO:0006403;RNA localization;1.22745987000488e-06!GO:0016044;membrane organization and biogenesis;1.36824623197667e-06!GO:0044432;endoplasmic reticulum part;1.43614643303081e-06!GO:0009141;nucleoside triphosphate metabolic process;1.71715323882696e-06!GO:0009055;electron carrier activity;1.93327576523406e-06!GO:0006752;group transfer coenzyme metabolic process;2.19456156499741e-06!GO:0005793;ER-Golgi intermediate compartment;2.56238723742909e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;2.88660699111211e-06!GO:0030097;hemopoiesis;3.3469731804434e-06!GO:0044440;endosomal part;3.41718953549886e-06!GO:0010008;endosome membrane;3.41718953549886e-06!GO:0030099;myeloid cell differentiation;3.86180452411358e-06!GO:0005643;nuclear pore;4.15044959355028e-06!GO:0022402;cell cycle process;4.63175786456815e-06!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;5.0680528039505e-06!GO:0042775;organelle ATP synthesis coupled electron transport;5.17828354570556e-06!GO:0042773;ATP synthesis coupled electron transport;5.17828354570556e-06!GO:0003714;transcription corepressor activity;5.54233099160366e-06!GO:0032446;protein modification by small protein conjugation;5.67672527388946e-06!GO:0051338;regulation of transferase activity;5.68716215357728e-06!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;5.73952771946263e-06!GO:0015399;primary active transmembrane transporter activity;5.73952771946263e-06!GO:0031982;vesicle;6.05800928644853e-06!GO:0032561;guanyl ribonucleotide binding;6.48688212726223e-06!GO:0019001;guanyl nucleotide binding;6.48688212726223e-06!GO:0031323;regulation of cellular metabolic process;6.86388979628773e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;7.28700685011446e-06!GO:0051789;response to protein stimulus;7.39407474260307e-06!GO:0006986;response to unfolded protein;7.39407474260307e-06!GO:0031980;mitochondrial lumen;7.54276192920911e-06!GO:0005759;mitochondrial matrix;7.54276192920911e-06!GO:0001816;cytokine production;7.66289674997984e-06!GO:0046649;lymphocyte activation;7.85503427699585e-06!GO:0006974;response to DNA damage stimulus;8.83377043115853e-06!GO:0030964;NADH dehydrogenase complex (quinone);9.30759264946981e-06!GO:0045271;respiratory chain complex I;9.30759264946981e-06!GO:0005747;mitochondrial respiratory chain complex I;9.30759264946981e-06!GO:0016567;protein ubiquitination;1.06473737710037e-05!GO:0009893;positive regulation of metabolic process;1.14058672717668e-05!GO:0043549;regulation of kinase activity;1.22718959002447e-05!GO:0006954;inflammatory response;1.2573589375602e-05!GO:0051028;mRNA transport;1.25883245952673e-05!GO:0051336;regulation of hydrolase activity;1.3196259248777e-05!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.42877868556431e-05!GO:0016197;endosome transport;1.44702463712378e-05!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.61096354866323e-05!GO:0005789;endoplasmic reticulum membrane;1.82706309925491e-05!GO:0006897;endocytosis;1.90510325133165e-05!GO:0010324;membrane invagination;1.90510325133165e-05!GO:0001775;cell activation;2.12880041021076e-05!GO:0045859;regulation of protein kinase activity;2.19512299536814e-05!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;2.3223404265882e-05!GO:0046983;protein dimerization activity;2.42732642600516e-05!GO:0030695;GTPase regulator activity;2.54911578472774e-05!GO:0042254;ribosome biogenesis and assembly;2.93782718811315e-05!GO:0031410;cytoplasmic vesicle;2.95015609221588e-05!GO:0003724;RNA helicase activity;3.0358217237387e-05!GO:0031902;late endosome membrane;3.33961385802411e-05!GO:0046930;pore complex;3.44652605022564e-05!GO:0051276;chromosome organization and biogenesis;3.49468984429367e-05!GO:0008632;apoptotic program;3.9404070419259e-05!GO:0005769;early endosome;4.00479423727675e-05!GO:0048475;coated membrane;4.00479423727675e-05!GO:0030117;membrane coat;4.00479423727675e-05!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;4.18212195675846e-05!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;4.23579055234445e-05!GO:0030120;vesicle coat;4.54764993618699e-05!GO:0030662;coated vesicle membrane;4.54764993618699e-05!GO:0004674;protein serine/threonine kinase activity;4.63148245064706e-05!GO:0006888;ER to Golgi vesicle-mediated transport;4.78995502740011e-05!GO:0005839;proteasome core complex (sensu Eukaryota);5.37089102311133e-05!GO:0002521;leukocyte differentiation;5.5368846875227e-05!GO:0031252;leading edge;5.62532221126204e-05!GO:0043566;structure-specific DNA binding;5.74365616726869e-05!GO:0046822;regulation of nucleocytoplasmic transport;5.79406189589556e-05!GO:0007050;cell cycle arrest;5.94803409375036e-05!GO:0031988;membrane-bound vesicle;6.49478334662867e-05!GO:0002520;immune system development;6.51883454477452e-05!GO:0005096;GTPase activator activity;6.61340382470571e-05!GO:0006952;defense response;6.71380237058334e-05!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;6.90790875252773e-05!GO:0048534;hemopoietic or lymphoid organ development;7.84779135516075e-05!GO:0006401;RNA catabolic process;8.64002959884373e-05!GO:0043492;ATPase activity, coupled to movement of substances;8.76511775210208e-05!GO:0006281;DNA repair;8.82963294585163e-05!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;8.82963294585163e-05!GO:0060090;molecular adaptor activity;9.61503180196079e-05!GO:0006613;cotranslational protein targeting to membrane;9.70334030147248e-05!GO:0007265;Ras protein signal transduction;9.72245940127608e-05!GO:0045941;positive regulation of transcription;9.85205343329907e-05!GO:0046519;sphingoid metabolic process;9.85205343329907e-05!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000105081499744793!GO:0042110;T cell activation;0.000118372651251239!GO:0045893;positive regulation of transcription, DNA-dependent;0.000119227725939225!GO:0005057;receptor signaling protein activity;0.000126990573840375!GO:0051223;regulation of protein transport;0.000129583986095439!GO:0010468;regulation of gene expression;0.000134766020166981!GO:0051427;hormone receptor binding;0.000136095372526282!GO:0022890;inorganic cation transmembrane transporter activity;0.000136095372526282!GO:0006672;ceramide metabolic process;0.000136365794007946!GO:0051168;nuclear export;0.000137894428527146!GO:0045259;proton-transporting ATP synthase complex;0.000141812208306826!GO:0003697;single-stranded DNA binding;0.000148874858379419!GO:0043085;positive regulation of catalytic activity;0.000155325112965981!GO:0005083;small GTPase regulator activity;0.000155606746297465!GO:0006402;mRNA catabolic process;0.000160350578444431!GO:0065002;intracellular protein transport across a membrane;0.00016133820695386!GO:0031325;positive regulation of cellular metabolic process;0.000164580980212048!GO:0004298;threonine endopeptidase activity;0.000168855237340591!GO:0016023;cytoplasmic membrane-bound vesicle;0.000178918432754764!GO:0006818;hydrogen transport;0.000183648761922016!GO:0035257;nuclear hormone receptor binding;0.000193193509893501!GO:0009060;aerobic respiration;0.000226634255335175!GO:0045892;negative regulation of transcription, DNA-dependent;0.000229031886129785!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000234439023071832!GO:0016740;transferase activity;0.000249408116760083!GO:0051707;response to other organism;0.000252108370381177!GO:0030532;small nuclear ribonucleoprotein complex;0.000254539938300744!GO:0015992;proton transport;0.000255959844568433!GO:0005667;transcription factor complex;0.000304122926182902!GO:0007041;lysosomal transport;0.000310130551970575!GO:0007034;vacuolar transport;0.000320427209683947!GO:0045637;regulation of myeloid cell differentiation;0.000321502575497106!GO:0008186;RNA-dependent ATPase activity;0.000336218199822194!GO:0008234;cysteine-type peptidase activity;0.000337759116346906!GO:0051090;regulation of transcription factor activity;0.000358956855515783!GO:0009117;nucleotide metabolic process;0.000381340610529!GO:0030036;actin cytoskeleton organization and biogenesis;0.000382897888017176!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.000397761178697709!GO:0033157;regulation of intracellular protein transport;0.000413497818752474!GO:0042306;regulation of protein import into nucleus;0.000413497818752474!GO:0002757;immune response-activating signal transduction;0.000415268044348673!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000417519717753379!GO:0005885;Arp2/3 protein complex;0.000492150796109008!GO:0000245;spliceosome assembly;0.000514177956544491!GO:0009719;response to endogenous stimulus;0.000593339349340777!GO:0045333;cellular respiration;0.000614091323708909!GO:0006919;caspase activation;0.000614984149846505!GO:0007040;lysosome organization and biogenesis;0.000657127370619929!GO:0001817;regulation of cytokine production;0.000657127370619929!GO:0005798;Golgi-associated vesicle;0.000750026428680741!GO:0002764;immune response-regulating signal transduction;0.000760469908113211!GO:0005761;mitochondrial ribosome;0.00076980215123916!GO:0000313;organellar ribosome;0.00076980215123916!GO:0003729;mRNA binding;0.000799117056375856!GO:0031202;RNA splicing factor activity, transesterification mechanism;0.000809099319837383!GO:0043281;regulation of caspase activity;0.00082497451501153!GO:0022415;viral reproductive process;0.000829475494083676!GO:0016281;eukaryotic translation initiation factor 4F complex;0.000836373133539331!GO:0019221;cytokine and chemokine mediated signaling pathway;0.000836373133539331!GO:0002274;myeloid leukocyte activation;0.000862166242338647!GO:0008654;phospholipid biosynthetic process;0.000875523551320948!GO:0016072;rRNA metabolic process;0.000924356438155947!GO:0044431;Golgi apparatus part;0.000940801969707683!GO:0004004;ATP-dependent RNA helicase activity;0.000943388545490317!GO:0042802;identical protein binding;0.000957155700000871!GO:0005637;nuclear inner membrane;0.000963855332601448!GO:0016301;kinase activity;0.000992254587607337!GO:0043280;positive regulation of caspase activity;0.00101572212390669!GO:0006643;membrane lipid metabolic process;0.00109969937309799!GO:0007033;vacuole organization and biogenesis;0.00110511774627681!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00116555180318072!GO:0042990;regulation of transcription factor import into nucleus;0.00116555180318072!GO:0042991;transcription factor import into nucleus;0.00116555180318072!GO:0016251;general RNA polymerase II transcription factor activity;0.00119146341225992!GO:0043623;cellular protein complex assembly;0.00119796134659761!GO:0006364;rRNA processing;0.0012226625426868!GO:0006350;transcription;0.00124007438671036!GO:0043087;regulation of GTPase activity;0.00125337382890746!GO:0005070;SH3/SH2 adaptor activity;0.00139035452132369!GO:0000151;ubiquitin ligase complex;0.00139035452132369!GO:0007005;mitochondrion organization and biogenesis;0.00142251705475339!GO:0065004;protein-DNA complex assembly;0.0014373231627578!GO:0002429;immune response-activating cell surface receptor signaling pathway;0.00147373614734718!GO:0007259;JAK-STAT cascade;0.0014917486889941!GO:0009165;nucleotide biosynthetic process;0.00159690100900446!GO:0006612;protein targeting to membrane;0.00166279234344567!GO:0009611;response to wounding;0.0016868750181912!GO:0001726;ruffle;0.00169484863007079!GO:0019904;protein domain specific binding;0.00182210886135441!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.00186737716993619!GO:0032940;secretion by cell;0.00194948196619464!GO:0002252;immune effector process;0.00200880017701251!GO:0033116;ER-Golgi intermediate compartment membrane;0.00207422667822122!GO:0001819;positive regulation of cytokine production;0.00220825616063581!GO:0030218;erythrocyte differentiation;0.00254982779242822!GO:0033673;negative regulation of kinase activity;0.00255770530401357!GO:0006469;negative regulation of protein kinase activity;0.00255770530401357!GO:0002768;immune response-regulating cell surface receptor signaling pathway;0.00258826120822001!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.00280849306440212!GO:0043433;negative regulation of transcription factor activity;0.00290787399425371!GO:0031072;heat shock protein binding;0.00303527946838159!GO:0051348;negative regulation of transferase activity;0.00316858586971286!GO:0003702;RNA polymerase II transcription factor activity;0.00320256652834142!GO:0051059;NF-kappaB binding;0.00326073161091224!GO:0030029;actin filament-based process;0.00330400992881115!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.00340132693575915!GO:0051023;regulation of immunoglobulin secretion;0.00365103333725839!GO:0045994;positive regulation of translational initiation by iron;0.00365103333725839!GO:0006099;tricarboxylic acid cycle;0.00386394213112622!GO:0046356;acetyl-CoA catabolic process;0.00386394213112622!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.0038890084087243!GO:0051187;cofactor catabolic process;0.00396391124958772!GO:0032386;regulation of intracellular transport;0.00407027861609104!GO:0042221;response to chemical stimulus;0.0040784886568817!GO:0004197;cysteine-type endopeptidase activity;0.00416125026798005!GO:0048487;beta-tubulin binding;0.00431680945967504!GO:0044262;cellular carbohydrate metabolic process;0.00434816226414837!GO:0045646;regulation of erythrocyte differentiation;0.00453873135983191!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00459369289588413!GO:0006468;protein amino acid phosphorylation;0.00477727608959066!GO:0002250;adaptive immune response;0.00479119848883035!GO:0002460;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.00479119848883035!GO:0000165;MAPKKK cascade;0.00494033172702458!GO:0045454;cell redox homeostasis;0.00514924894743494!GO:0000082;G1/S transition of mitotic cell cycle;0.00529354269067964!GO:0016363;nuclear matrix;0.00547620106679193!GO:0005741;mitochondrial outer membrane;0.00547620106679193!GO:0031901;early endosome membrane;0.005483752037743!GO:0046966;thyroid hormone receptor binding;0.00557612658133696!GO:0050900;leukocyte migration;0.00560800033141081!GO:0030149;sphingolipid catabolic process;0.00590031662482168!GO:0051098;regulation of binding;0.00590243035541326!GO:0018193;peptidyl-amino acid modification;0.00600366852472395!GO:0002697;regulation of immune effector process;0.00608565370937114!GO:0050851;antigen receptor-mediated signaling pathway;0.00611932779549364!GO:0005099;Ras GTPase activator activity;0.00614344729007572!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.0061703366023866!GO:0006611;protein export from nucleus;0.00630862717542699!GO:0006352;transcription initiation;0.00649520012258818!GO:0008383;manganese superoxide dismutase activity;0.00681458517190649!GO:0001315;age-dependent response to reactive oxygen species;0.00681458517190649!GO:0006333;chromatin assembly or disassembly;0.00690858442401503!GO:0002573;myeloid leukocyte differentiation;0.00696158014173226!GO:0019377;glycolipid catabolic process;0.00737741620568584!GO:0051345;positive regulation of hydrolase activity;0.0075523368964168!GO:0006091;generation of precursor metabolites and energy;0.00761283719554503!GO:0002684;positive regulation of immune system process;0.00770864298533923!GO:0000785;chromatin;0.00783592519529912!GO:0045639;positive regulation of myeloid cell differentiation;0.00892761966933258!GO:0032943;mononuclear cell proliferation;0.00895790674569983!GO:0046651;lymphocyte proliferation;0.00895790674569983!GO:0043021;ribonucleoprotein binding;0.00910061097953874!GO:0006607;NLS-bearing substrate import into nucleus;0.00912056078032756!GO:0042113;B cell activation;0.0091808967318819!GO:0000278;mitotic cell cycle;0.0092863051711321!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;0.00929347232169253!GO:0004812;aminoacyl-tRNA ligase activity;0.00929347232169253!GO:0016875;ligase activity, forming carbon-oxygen bonds;0.00929347232169253!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00929347232169253!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00929347232169253!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00929347232169253!GO:0006084;acetyl-CoA metabolic process;0.00940304550174355!GO:0043621;protein self-association;0.00958439639597059!GO:0002822;regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.;0.00964392008002869!GO:0002819;regulation of adaptive immune response;0.00964392008002869!GO:0031625;ubiquitin protein ligase binding;0.00964392008002869!GO:0005813;centrosome;0.00965983283281891!GO:0016791;phosphoric monoester hydrolase activity;0.00965983283281891!GO:0004185;serine carboxypeptidase activity;0.00967970785238213!GO:0030658;transport vesicle membrane;0.00968540055964153!GO:0046479;glycosphingolipid catabolic process;0.0101793590424243!GO:0030041;actin filament polymerization;0.0103328993079558!GO:0050778;positive regulation of immune response;0.0103598196790938!GO:0006891;intra-Golgi vesicle-mediated transport;0.0103814703908857!GO:0016779;nucleotidyltransferase activity;0.0105421763411149!GO:0032318;regulation of Ras GTPase activity;0.0105777069428451!GO:0000139;Golgi membrane;0.0109280270625999!GO:0048872;homeostasis of number of cells;0.0109456664531965!GO:0033549;MAP kinase phosphatase activity;0.0112666681661739!GO:0017017;MAP kinase tyrosine/serine/threonine phosphatase activity;0.0112666681661739!GO:0051049;regulation of transport;0.0113184417571558!GO:0009109;coenzyme catabolic process;0.0113702131266881!GO:0004860;protein kinase inhibitor activity;0.0114831625940486!GO:0002682;regulation of immune system process;0.0114971744617944!GO:0019079;viral genome replication;0.0116455399175299!GO:0051092;activation of NF-kappaB transcription factor;0.0117527603639048!GO:0048500;signal recognition particle;0.0118590698198685!GO:0002444;myeloid leukocyte mediated immunity;0.0119775187884577!GO:0030098;lymphocyte differentiation;0.0120971466213043!GO:0008283;cell proliferation;0.0122487690199896!GO:0005152;interleukin-1 receptor antagonist activity;0.0122645475309156!GO:0030353;fibroblast growth factor receptor antagonist activity;0.0122645475309156!GO:0051051;negative regulation of transport;0.0131847336517639!GO:0030518;steroid hormone receptor signaling pathway;0.0132420725517607!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.0132952842978025!GO:0019882;antigen processing and presentation;0.0134162898225762!GO:0031968;organelle outer membrane;0.0134316179760169!GO:0008139;nuclear localization sequence binding;0.0135690256970302!GO:0032763;regulation of mast cell cytokine production;0.0138007396300525!GO:0032762;mast cell cytokine production;0.0138007396300525!GO:0030503;regulation of cell redox homeostasis;0.0138814302805613!GO:0019220;regulation of phosphate metabolic process;0.0140650174206141!GO:0051174;regulation of phosphorus metabolic process;0.0140650174206141!GO:0043038;amino acid activation;0.0142073845777662!GO:0006418;tRNA aminoacylation for protein translation;0.0142073845777662!GO:0043039;tRNA aminoacylation;0.0142073845777662!GO:0006399;tRNA metabolic process;0.0142999705380769!GO:0003690;double-stranded DNA binding;0.0143301150890471!GO:0030258;lipid modification;0.0143849073383463!GO:0033367;protein localization in mast cell secretory granule;0.0144789797239975!GO:0033365;protein localization in organelle;0.0144789797239975!GO:0033371;T cell secretory granule organization and biogenesis;0.0144789797239975!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.0144789797239975!GO:0033375;protease localization in T cell secretory granule;0.0144789797239975!GO:0042629;mast cell granule;0.0144789797239975!GO:0033377;maintenance of protein localization in T cell secretory granule;0.0144789797239975!GO:0033364;mast cell secretory granule organization and biogenesis;0.0144789797239975!GO:0033380;granzyme B localization in T cell secretory granule;0.0144789797239975!GO:0033379;maintenance of protease localization in T cell secretory granule;0.0144789797239975!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.0144789797239975!GO:0033368;protease localization in mast cell secretory granule;0.0144789797239975!GO:0033366;protein localization in secretory granule;0.0144789797239975!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.0144789797239975!GO:0033374;protein localization in T cell secretory granule;0.0144789797239975!GO:0019210;kinase inhibitor activity;0.0145920337868923!GO:0000209;protein polyubiquitination;0.0146745269257702!GO:0019867;outer membrane;0.0147811624083847!GO:0002443;leukocyte mediated immunity;0.0148973475681009!GO:0002440;production of molecular mediator of immune response;0.0148978473098411!GO:0006665;sphingolipid metabolic process;0.0149508316053368!GO:0030127;COPII vesicle coat;0.0149919995185484!GO:0012507;ER to Golgi transport vesicle membrane;0.0149919995185484!GO:0046467;membrane lipid biosynthetic process;0.0152296404353398!GO:0002237;response to molecule of bacterial origin;0.0154080379297229!GO:0000339;RNA cap binding;0.0156424556985779!GO:0045746;negative regulation of Notch signaling pathway;0.0156676029432001!GO:0030660;Golgi-associated vesicle membrane;0.0157253347171859!GO:0043300;regulation of leukocyte degranulation;0.0157367749634211!GO:0008286;insulin receptor signaling pathway;0.0159132105727544!GO:0043407;negative regulation of MAP kinase activity;0.0159212582338715!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0164322043286875!GO:0003725;double-stranded RNA binding;0.0166792783847433!GO:0048146;positive regulation of fibroblast proliferation;0.0166949255719493!GO:0030867;rough endoplasmic reticulum membrane;0.0173292683485983!GO:0030521;androgen receptor signaling pathway;0.0174370473878626!GO:0051347;positive regulation of transferase activity;0.0175642112278455!GO:0008333;endosome to lysosome transport;0.0175809977030476!GO:0019901;protein kinase binding;0.0176249139641527!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0176903875759186!GO:0045047;protein targeting to ER;0.0176903875759186!GO:0000118;histone deacetylase complex;0.0177413178318924!GO:0051329;interphase of mitotic cell cycle;0.0178702355154223!GO:0019058;viral infectious cycle;0.0178702355154223!GO:0051252;regulation of RNA metabolic process;0.0178702355154223!GO:0045792;negative regulation of cell size;0.0191530944422847!GO:0017091;AU-rich element binding;0.01922522823442!GO:0050779;RNA destabilization;0.01922522823442!GO:0000289;poly(A) tail shortening;0.01922522823442!GO:0043488;regulation of mRNA stability;0.0192413588795745!GO:0043487;regulation of RNA stability;0.0192413588795745!GO:0030027;lamellipodium;0.0196264027472826!GO:0045944;positive regulation of transcription from RNA polymerase II promoter;0.0197770228652854!GO:0042613;MHC class II protein complex;0.0200848678626149!GO:0051325;interphase;0.0201785858713499!GO:0043022;ribosome binding;0.0202360721986659!GO:0005048;signal sequence binding;0.0204407670391491!GO:0002467;germinal center formation;0.0205154436881137!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0205506587797476!GO:0051247;positive regulation of protein metabolic process;0.0205506587797476!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0207777574539812!GO:0042108;positive regulation of cytokine biosynthetic process;0.0209170935371091!GO:0030134;ER to Golgi transport vesicle;0.0211090150185076!GO:0045576;mast cell activation;0.0211090150185076!GO:0030217;T cell differentiation;0.0214377193630995!GO:0051091;positive regulation of transcription factor activity;0.0215578142565695!GO:0008637;apoptotic mitochondrial changes;0.0217394880131868!GO:0005815;microtubule organizing center;0.0219906755893857!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0220065773174607!GO:0045449;regulation of transcription;0.0224039729695474!GO:0042107;cytokine metabolic process;0.0224621657664322!GO:0030308;negative regulation of cell growth;0.0227825813909566!GO:0008312;7S RNA binding;0.0228264629684699!GO:0001776;leukocyte homeostasis;0.023093259371485!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.0235788785669982!GO:0006650;glycerophospholipid metabolic process;0.023743408410231!GO:0050776;regulation of immune response;0.0238170118128327!GO:0048144;fibroblast proliferation;0.0238170118128327!GO:0048145;regulation of fibroblast proliferation;0.0238170118128327!GO:0006414;translational elongation;0.0243811907571884!GO:0042992;negative regulation of transcription factor import into nucleus;0.0244125520670022!GO:0042308;negative regulation of protein import into nucleus;0.0244125520670022!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0248957059531143!GO:0009891;positive regulation of biosynthetic process;0.0249579133806404!GO:0006749;glutathione metabolic process;0.0250327213130091!GO:0005905;coated pit;0.0251024927071696!GO:0051251;positive regulation of lymphocyte activation;0.0252187192580733!GO:0042348;NF-kappaB import into nucleus;0.0254798089021261!GO:0042345;regulation of NF-kappaB import into nucleus;0.0254798089021261!GO:0031327;negative regulation of cellular biosynthetic process;0.025485346509389!GO:0005484;SNAP receptor activity;0.025485346509389!GO:0009890;negative regulation of biosynthetic process;0.0257518639398278!GO:0003727;single-stranded RNA binding;0.0257518639398278!GO:0030118;clathrin coat;0.0257518639398278!GO:0008361;regulation of cell size;0.0257518639398278!GO:0015036;disulfide oxidoreductase activity;0.0258074076542122!GO:0006351;transcription, DNA-dependent;0.0258291989166899!GO:0042092;T-helper 2 type immune response;0.0259504377022397!GO:0006595;polyamine metabolic process;0.0262960788151922!GO:0048471;perinuclear region of cytoplasm;0.026660735877152!GO:0019371;cyclooxygenase pathway;0.026660735877152!GO:0043299;leukocyte degranulation;0.0267279160818312!GO:0017166;vinculin binding;0.0272991342758789!GO:0042611;MHC protein complex;0.02735614652658!GO:0006458;'de novo' protein folding;0.02735614652658!GO:0051084;'de novo' posttranslational protein folding;0.02735614652658!GO:0002699;positive regulation of immune effector process;0.0273589517128634!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0274123203789788!GO:0032774;RNA biosynthetic process;0.0276651239530239!GO:0042098;T cell proliferation;0.0278266194845152!GO:0000287;magnesium ion binding;0.0278839855644052!GO:0004428;inositol or phosphatidylinositol kinase activity;0.028328777218534!GO:0002824;positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.028676145031158!GO:0002821;positive regulation of adaptive immune response;0.028676145031158!GO:0006644;phospholipid metabolic process;0.029034390620441!GO:0005694;chromosome;0.0295956545927919!GO:0002718;regulation of cytokine production during immune response;0.0297587227841944!GO:0002367;cytokine production during immune response;0.0297587227841944!GO:0002700;regulation of production of molecular mediator of immune response;0.0297587227841944!GO:0002263;cell activation during immune response;0.0297587227841944!GO:0042093;T-helper cell differentiation;0.0297587227841944!GO:0002366;leukocyte activation during immune response;0.0297587227841944!GO:0002293;alpha-beta T cell differentiation during immune response;0.0297587227841944!GO:0002294;CD4-positive, alpha-beta T cell differentiation during immune response;0.0297587227841944!GO:0002285;lymphocyte activation during immune response;0.0297587227841944!GO:0002292;T cell differentiation during immune response;0.0297587227841944!GO:0002286;T cell activation during immune response;0.0297587227841944!GO:0046578;regulation of Ras protein signal transduction;0.029777393782565!GO:0015923;mannosidase activity;0.0299556743913542!GO:0046631;alpha-beta T cell activation;0.0299556743913542!GO:0051101;regulation of DNA binding;0.0300585177861576!GO:0045045;secretory pathway;0.0301765628797449!GO:0004177;aminopeptidase activity;0.030351436747034!GO:0051050;positive regulation of transport;0.0304438225887692!GO:0030137;COPI-coated vesicle;0.0312812718315005!GO:0005149;interleukin-1 receptor binding;0.0312833863604806!GO:0030384;phosphoinositide metabolic process;0.0317209957773484!GO:0051052;regulation of DNA metabolic process;0.0318404241133514!GO:0008629;induction of apoptosis by intracellular signals;0.0321200476527578!GO:0004722;protein serine/threonine phosphatase activity;0.0322245655696249!GO:0030100;regulation of endocytosis;0.0326558951357322!GO:0033674;positive regulation of kinase activity;0.0327875604353045!GO:0050811;GABA receptor binding;0.032803336789925!GO:0030176;integral to endoplasmic reticulum membrane;0.033323896064519!GO:0030377;U-plasminogen activator receptor activity;0.0335594982095943!GO:0050865;regulation of cell activation;0.0340266888360678!GO:0019843;rRNA binding;0.0342939983614088!GO:0006689;ganglioside catabolic process;0.0343976656398244!GO:0042089;cytokine biosynthetic process;0.0348123263043933!GO:0042832;defense response to protozoan;0.0350292443855902!GO:0042035;regulation of cytokine biosynthetic process;0.0350498889914025!GO:0046823;negative regulation of nucleocytoplasmic transport;0.03507626810147!GO:0035035;histone acetyltransferase binding;0.0353228653513701!GO:0031647;regulation of protein stability;0.03608455430637!GO:0030155;regulation of cell adhesion;0.03608455430637!GO:0005669;transcription factor TFIID complex;0.0361963315663998!GO:0044255;cellular lipid metabolic process;0.0361963315663998!GO:0007162;negative regulation of cell adhesion;0.0363200822512943!GO:0000096;sulfur amino acid metabolic process;0.0364112148991366!GO:0001562;response to protozoan;0.0366959701665383!GO:0032760;positive regulation of tumor necrosis factor production;0.0370677507194129!GO:0043086;negative regulation of catalytic activity;0.0371147037568162!GO:0015631;tubulin binding;0.0373805748533335!GO:0048002;antigen processing and presentation of peptide antigen;0.0373805748533335!GO:0042088;T-helper 1 type immune response;0.0376792661453929!GO:0007165;signal transduction;0.0377623246723785!GO:0050727;regulation of inflammatory response;0.0377623246723785!GO:0031347;regulation of defense response;0.0377623246723785!GO:0030663;COPI coated vesicle membrane;0.0379567213171574!GO:0030126;COPI vesicle coat;0.0379567213171574!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0380119845423423!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0380119845423423!GO:0051224;negative regulation of protein transport;0.0392247147330631!GO:0008624;induction of apoptosis by extracellular signals;0.0394272412343133!GO:0030374;ligand-dependent nuclear receptor transcription coactivator activity;0.0394769575643356!GO:0051056;regulation of small GTPase mediated signal transduction;0.0395177898447559!GO:0043304;regulation of mast cell degranulation;0.0396471733844465!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.0396471733844465!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.0396471733844465!GO:0009126;purine nucleoside monophosphate metabolic process;0.0396471733844465!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.0396471733844465!GO:0030595;leukocyte chemotaxis;0.0401293160125103!GO:0050870;positive regulation of T cell activation;0.0405310499648968!GO:0000738;DNA catabolic process, exonucleolytic;0.0405436002446325!GO:0045936;negative regulation of phosphate metabolic process;0.0407414410775247!GO:0006376;mRNA splice site selection;0.0410506214110501!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0410506214110501!GO:0030522;intracellular receptor-mediated signaling pathway;0.0410506214110501!GO:0051881;regulation of mitochondrial membrane potential;0.0416921317057636!GO:0006338;chromatin remodeling;0.0417851601969201!GO:0004563;beta-N-acetylhexosaminidase activity;0.0417952521127801!GO:0030693;caspase activity;0.0424263892938555!GO:0045089;positive regulation of innate immune response;0.0427651707739893!GO:0045088;regulation of innate immune response;0.0427651707739893!GO:0006979;response to oxidative stress;0.0428183464531274!GO:0002224;toll-like receptor signaling pathway;0.0428183464531274!GO:0002221;pattern recognition receptor signaling pathway;0.0428183464531274!GO:0004672;protein kinase activity;0.0430185092297911!GO:0019883;antigen processing and presentation of endogenous antigen;0.0430932939617298!GO:0045603;positive regulation of endothelial cell differentiation;0.0433502229594895!GO:0046466;membrane lipid catabolic process;0.0437101379667618!GO:0042326;negative regulation of phosphorylation;0.0438839591311096!GO:0030133;transport vesicle;0.0438839591311096!GO:0046982;protein heterodimerization activity;0.0438839591311096!GO:0042325;regulation of phosphorylation;0.0439941999870344!GO:0005350;pyrimidine transmembrane transporter activity;0.0439941999870344!GO:0015855;pyrimidine transport;0.0439941999870344!GO:0015288;porin activity;0.0439941999870344!GO:0045727;positive regulation of translation;0.0440511706660874!GO:0006935;chemotaxis;0.0440511706660874!GO:0042330;taxis;0.0440511706660874!GO:0006260;DNA replication;0.0442805144654005!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0445369296018915!GO:0042347;negative regulation of NF-kappaB import into nucleus;0.0452327278516026!GO:0042127;regulation of cell proliferation;0.0463316626676928!GO:0006914;autophagy;0.0463716310186871!GO:0006984;ER-nuclear signaling pathway;0.0465377002845446!GO:0043071;positive regulation of non-apoptotic programmed cell death;0.0466120641061577!GO:0006405;RNA export from nucleus;0.0467235184136673!GO:0008320;protein transmembrane transporter activity;0.047457872870302!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0477105801060152!GO:0051249;regulation of lymphocyte activation;0.0477453361283093!GO:0051900;regulation of mitochondrial depolarization;0.048168125093639!GO:0017148;negative regulation of translation;0.048874598476362!GO:0045860;positive regulation of protein kinase activity;0.0497905338158106 | |||
|sample_id=11878 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue= | |||
|top_motifs=FOSL2:6.52050805241;BACH2:6.2184198577;FOS_FOS{B,L1}_JUN{B,D}:6.12969421626;NFE2:6.10434856268;HLF:5.36646609595;NFE2L2:5.03989565259;PAX2:4.82385842633;CEBPA,B_DDIT3:4.71831693999;SREBF1,2:4.51878434348;NFKB1_REL_RELA:4.292479978;ATF4:3.91992037008;FOXP3:3.72977278338;NR1H4:3.66720179775;ATF5_CREB3:3.66670257545;NFIL3:3.6437675849;SPIB:3.6095595279;HSF1,2:3.45263831776;NFATC1..3:3.1802021358;JUN:3.17629157198;NANOG{mouse}:3.13740749297;SPI1:3.04438663053;CREB1:3.04267853809;ETS1,2:2.97576815481;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:2.90910136391;PAX3,7:2.86395492417;ATF6:2.80807382796;MAFB:2.7995993143;PAX8:2.70706902622;IRF7:2.69794026072;HOX{A5,B5}:2.57337538919;RUNX1..3:2.55827963562;NFE2L1:2.5312406569;IRF1,2:2.43565954293;DMAP1_NCOR{1,2}_SMARC:2.31830497235;ATF2:2.09828199002;STAT5{A,B}:2.02404853519;FOXN1:1.96155436373;XBP1:1.80403189763;PDX1:1.72366044199;STAT2,4,6:1.66897578869;TGIF1:1.46409286657;FOXO1,3,4:1.2728981511;EP300:1.09019423251;HIF1A:1.06705610028;PAX1,9:1.04865558594;HMGA1,2:1.03256059116;CDX1,2,4:0.944346670791;ELF1,2,4:0.895891491207;RXRA_VDR{dimer}:0.859967147446;ZBTB16:0.799587055391;HOXA9_MEIS1:0.709637760001;TBP:0.557865205843;PAX4:0.523232610717;ALX4:0.300964467142;MEF2{A,B,C,D}:0.290974238476;IKZF1:0.288190172716;RBPJ:0.280317886853;ESR1:0.251936758763;SRF:0.20692589494;EN1,2:0.206314376154;HMX1:0.20274241202;POU5F1:0.183734010147;POU2F1..3:0.172981479851;BPTF:0.167762889666;SMAD1..7,9:0.14781732086;OCT4_SOX2{dimer}:0.130051603681;PRDM1:0.124349872263;GLI1..3:0.108225054335;HES1:0.0690145543377;NANOG:0.0657380614497;IKZF2:0.0437549471622;AHR_ARNT_ARNT2:-0.0542783022872;VSX1,2:-0.059625856556;RORA:-0.073290642685;RFX2..5_RFXANK_RFXAP:-0.103692612918;PPARG:-0.130187686423;NR3C1:-0.154969474142;GATA4:-0.265417442769;POU3F1..4:-0.347568012014;NR6A1:-0.348839014235;HBP1_HMGB_SSRP1_UBTF:-0.426060228955;FOX{D1,D2}:-0.443475007194;EGR1..3:-0.447095003007;SOX2:-0.597402773034;FOXD3:-0.612433020336;MYB:-0.648212294935;TLX2:-0.661634409913;NKX3-1:-0.726363232404;FOXL1:-0.799492949828;PITX1..3:-0.846379071418;DBP:-0.863707276486;STAT1,3:-0.874586793723;NFIX:-0.890031982251;MZF1:-0.913572356759;TFCP2:-0.92678778765;FOXP1:-1.00182342474;PAX6:-1.02018569104;ESRRA:-1.082628918;FOXM1:-1.08990480034;ZNF238:-1.15138276335;ALX1:-1.16482566783;NKX2-1,4:-1.17322896368;MED-1{core}:-1.18860930239;T:-1.23463616903;NHLH1,2:-1.23793205491;HOX{A4,D4}:-1.24012306793;TEF:-1.31280511372;REST:-1.33763009904;PRRX1,2:-1.33879379583;RXR{A,B,G}:-1.3665658438;POU6F1:-1.40508976703;HNF1A:-1.41436128297;SOX5:-1.42528933216;TAL1_TCF{3,4,12}:-1.43024931921;TBX4,5:-1.44115073713;TFDP1:-1.44468066864;FOXA2:-1.45884197156;CUX2:-1.50064322711;GZF1:-1.50471203031;MYFfamily:-1.50789164163;NKX6-1,2:-1.51704195024;GATA6:-1.52091091344;MTE{core}:-1.54753396051;E2F1..5:-1.56805300132;CRX:-1.58658156946;ZNF384:-1.5946156978;HNF4A_NR2F1,2:-1.61547313125;RXR{A,B,G}_{NR1H2,PPAR}dimers:-1.6202185926;NKX2-3_NKX2-5:-1.62509470027;BREu{core}:-1.66982311288;ZFP161:-1.71479029815;TFAP2B:-1.76698830019;TEAD1:-1.78245872485;ADNP_IRX_SIX_ZHX:-1.78541658862;RFX1:-1.82937327773;FOX{F1,F2,J1}:-1.83751854488;SP1:-1.85531156936;SOX{8,9,10}:-1.86358677859;GTF2A1,2:-1.89546681755;PATZ1:-1.97124007927;HOX{A6,A7,B6,B7}:-1.97817656938;SPZ1:-1.97947541536;FOX{I1,J2}:-1.97949497836;TFAP4:-1.98516942205;POU1F1:-2.03169988125;GCM1,2:-2.03468535834;ZBTB6:-2.0396766447;MYBL2:-2.06101008986;bHLH_family:-2.07471294875;TP53:-2.0751757957;MTF1:-2.1162861648;GFI1B:-2.11661652104;MAZ:-2.13722059818;NKX3-2:-2.19520866474;GTF2I:-2.20047241496;NFY{A,B,C}:-2.2243635344;CDC5L:-2.24637469549;PBX1:-2.29946174163;ELK1,4_GABP{A,B1}:-2.30872459164;ZEB1:-2.33635672984;RREB1:-2.34899481717;TLX1..3_NFIC{dimer}:-2.35462894382;XCPE1{core}:-2.38612022749;TFAP2{A,C}:-2.49203897869;AIRE:-2.49633613902;HIC1:-2.50853150624;SNAI1..3:-2.61781742874;ZNF148:-2.62491293785;ONECUT1,2:-2.62917397987;ZIC1..3:-2.68160427671;FOXQ1:-2.71304862816;MYOD1:-2.73046697175;NR5A1,2:-2.74041477129;ARID5B:-2.76619515515;SOX17:-2.83401988128;EBF1:-2.83692821129;UFEwm:-2.85677779454;KLF4:-3.07054807886;NRF1:-3.07670218874;GFI1:-3.17160912373;NKX2-2,8:-3.19817930859;LHX3,4:-3.31659398218;ZNF423:-3.34370518398;LMO2:-3.38114059114;HAND1,2:-3.40686748937;EVI1:-3.4423882862;AR:-3.4469220281;YY1:-3.82879229547;ZNF143:-3.87860233806;PAX5:-3.97609564329;LEF1_TCF7_TCF7L1,2:-3.98564280107;TOPORS:-4.04202531741 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11878-125C6;search_select_hide=table117:FF:11878-125C6 | |||
}} | }} |
Latest revision as of 18:25, 4 June 2020
Name: | CD14+ monocytes - treated with Candida, donor2 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13488 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13488
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13488
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.117 |
10 | 10 | 0.018 |
100 | 100 | 0.896 |
101 | 101 | 0.828 |
102 | 102 | 0.899 |
103 | 103 | 0.331 |
104 | 104 | 0.538 |
105 | 105 | 0.0689 |
106 | 106 | 0.00123 |
107 | 107 | 0.389 |
108 | 108 | 0.633 |
109 | 109 | 0.431 |
11 | 11 | 0.225 |
110 | 110 | 0.158 |
111 | 111 | 0.0987 |
112 | 112 | 0.373 |
113 | 113 | 0.51 |
114 | 114 | 0.0357 |
115 | 115 | 0.197 |
116 | 116 | 0.987 |
117 | 117 | 0.0746 |
118 | 118 | 0.228 |
119 | 119 | 0.137 |
12 | 12 | 0.307 |
120 | 120 | 0.944 |
121 | 121 | 0.503 |
122 | 122 | 0.563 |
123 | 123 | 0.359 |
124 | 124 | 0.616 |
125 | 125 | 0.335 |
126 | 126 | 0.27 |
127 | 127 | 0.592 |
128 | 128 | 0.0493 |
129 | 129 | 0.471 |
13 | 13 | 0.0834 |
130 | 130 | 0.245 |
131 | 131 | 0.969 |
132 | 132 | 0.0392 |
133 | 133 | 0.67 |
134 | 134 | 0.585 |
135 | 135 | 0.932 |
136 | 136 | 0.941 |
137 | 137 | 0.0363 |
138 | 138 | 0.373 |
139 | 139 | 0.0824 |
14 | 14 | 0.549 |
140 | 140 | 0.195 |
141 | 141 | 0.306 |
142 | 142 | 0.01 |
143 | 143 | 0.0213 |
144 | 144 | 0.626 |
145 | 145 | 0.455 |
146 | 146 | 0.817 |
147 | 147 | 0.678 |
148 | 148 | 0.0195 |
149 | 149 | 0.885 |
15 | 15 | 0.198 |
150 | 150 | 0.353 |
151 | 151 | 0.528 |
152 | 152 | 0.433 |
153 | 153 | 0.615 |
154 | 154 | 0.657 |
155 | 155 | 0.989 |
156 | 156 | 0.764 |
157 | 157 | 0.403 |
158 | 158 | 0.0179 |
159 | 159 | 0.305 |
16 | 16 | 0.409 |
160 | 160 | 0.434 |
161 | 161 | 0.444 |
162 | 162 | 0.189 |
163 | 163 | 0.0932 |
164 | 164 | 0.113 |
165 | 165 | 0.326 |
166 | 166 | 0.642 |
167 | 167 | 0.147 |
168 | 168 | 0.169 |
169 | 169 | 0.0324 |
17 | 17 | 0.262 |
18 | 18 | 0.103 |
19 | 19 | 0.57 |
2 | 2 | 0.376 |
20 | 20 | 0.191 |
21 | 21 | 0.742 |
22 | 22 | 0.41 |
23 | 23 | 0.0667 |
24 | 24 | 0.445 |
25 | 25 | 0.498 |
26 | 26 | 0.075 |
27 | 27 | 0.448 |
28 | 28 | 0.436 |
29 | 29 | 0.259 |
3 | 3 | 0.182 |
30 | 30 | 0.428 |
31 | 31 | 0.773 |
32 | 32 | 0.373 |
33 | 33 | 0.285 |
34 | 34 | 0.844 |
35 | 35 | 0.106 |
36 | 36 | 0.0561 |
37 | 37 | 0.0767 |
38 | 38 | 0.359 |
39 | 39 | 0.911 |
4 | 4 | 0.837 |
40 | 40 | 0.181 |
41 | 41 | 0.0125 |
42 | 42 | 0.39 |
43 | 43 | 0.0254 |
44 | 44 | 0.5 |
45 | 45 | 0.852 |
46 | 46 | 0.229 |
47 | 47 | 0.678 |
48 | 48 | 0.591 |
49 | 49 | 0.12 |
5 | 5 | 0.338 |
50 | 50 | 0.972 |
51 | 51 | 0.588 |
52 | 52 | 0.458 |
53 | 53 | 0.623 |
54 | 54 | 0.503 |
55 | 55 | 0.613 |
56 | 56 | 0.683 |
57 | 57 | 0.839 |
58 | 58 | 0.199 |
59 | 59 | 0.333 |
6 | 6 | 0.836 |
60 | 60 | 0.0787 |
61 | 61 | 0.621 |
62 | 62 | 0.124 |
63 | 63 | 0.616 |
64 | 64 | 0.435 |
65 | 65 | 0.269 |
66 | 66 | 0.305 |
67 | 67 | 0.482 |
68 | 68 | 0.803 |
69 | 69 | 0.447 |
7 | 7 | 0.255 |
70 | 70 | 0.0819 |
71 | 71 | 0.0297 |
72 | 72 | 0.166 |
73 | 73 | 0.204 |
74 | 74 | 0.0485 |
75 | 75 | 0.153 |
76 | 76 | 0.104 |
77 | 77 | 0.707 |
78 | 78 | 0.116 |
79 | 79 | 0.602 |
8 | 8 | 0.415 |
80 | 80 | 0.251 |
81 | 81 | 0.354 |
82 | 82 | 0.306 |
83 | 83 | 0.00723 |
84 | 84 | 0.109 |
85 | 85 | 0.054 |
86 | 86 | 0.0474 |
87 | 87 | 0.655 |
88 | 88 | 0.786 |
89 | 89 | 0.311 |
9 | 9 | 0.483 |
90 | 90 | 0.163 |
91 | 91 | 0.316 |
92 | 92 | 0.37 |
93 | 93 | 0.414 |
94 | 94 | 0.0982 |
95 | 95 | 0.502 |
96 | 96 | 0.482 |
97 | 97 | 0.553 |
98 | 98 | 0.165 |
99 | 99 | 0.0271 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13488
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0011104 human CD14-positive monocytes - treated with Candida sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000766 (myeloid leukocyte)
0000219 (motile cell)
0000325 (stuff accumulating cell)
0000473 (defensive cell)
0000234 (phagocyte)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0000255 (eukaryotic cell)
0000576 (monocyte)
0000860 (classical monocyte)
0002057 (CD14-positive, CD16-negative classical monocyte)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
0000625 (experimental infection sample)
0000350 (experimentally modified sample)
0000635 (Candida treatment sample)
0011104 (human CD14-positive monocytes - treated with Candida sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)
CL:0002057 (CD14-positive, CD16-negative classical monocyte)