FF:11882-125D1: Difference between revisions
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{{f5samples | {{f5samples | ||
|ancestors_in_anatomy_facet= | |DRA_sample_Accession=CAGE@SAMD00005810 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |accession_numbers=CAGE;DRX008158;DRR009030;DRZ000455;DRZ001840;DRZ011805;DRZ013190 | ||
|ancestors_in_anatomy_facet= | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000766,CL:0000219,CL:0000325,CL:0000473,CL:0000234,CL:0000738,CL:0002087,CL:0000255,CL:0000576,CL:0000860,CL:0002057 | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
|ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001,FF:0000625,FF:0000350,FF:0000631,FF:0011444 | |||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
|expression_enrichment_score=chr2:68592406..68592424,+!p1@PLEK!3.95!8845.02!PLEK;;chr16:85932760..85932775,+!p1@IRF8!3.06!1142.41!IRF8;;chr10:35484053..35484076,+!p1@CREM!2.70!1201.49!CREM;;chr10:64576105..64576133,-!p1@EGR2!2.69!976.05!EGR2;;chr11:47400078..47400106,-!p1@SPI1!2.62!415.48!SPI1;;chr7:115670804..115670825,-!p1@TFEC!2.47!291.68!TFEC;;chr12:54778471..54778528,-!p1@ZNF385A!2.29!193.73!ZNF385A;;chr11:64764435..64764449,-!p1@BATF2!2.20!213.06!BATF2;;chr1:158985493..158985535,+!p4@IFI16!2.14!205.68!IFI16;;chr6:106534192..106534224,+!p1@PRDM1!2.07!314.92!PRDM1;;chr11:47399947..47399961,-!p3@SPI1!2.06!112.72!SPI1;;chr20:39317868..39317884,-!p1@MAFB!2.05!1245.80!MAFB;;chr21:36260295..36260310,-!p3@RUNX1!2.05!175.49!RUNX1;;chr2:68592394..68592405,+!p2@PLEK!2.04!108.38!PLEK;;chr10:35484090..35484104,+!p6@CREM!2.04!107.94!CREM;;chr16:31885093..31885165,+!p1@ZNF267!2.02!1486.87!ZNF267;;chr19:45971246..45971265,+!p1@FOSB!2.01!1769.87!FOSB;;chr6:36355431..36355466,-!p1@ETV7!2.01!101.43!ETV7;;chr21:34442439..34442455,+!p1@OLIG1!1.98!94.48!OLIG1;;chr10:31288398..31288455,-!p2@ZNF438!1.93!97.30!ZNF438;;chr11:47400062..47400077,-!p2@SPI1!1.93!84.05!SPI1;;chr5:131826457..131826514,-!p1@IRF1!1.91!2956.59!IRF1;;chr17:45810594..45810608,+!p1@TBX21!1.89!76.67!TBX21;;chr21:30671690..30671762,+!p2@BACH1!1.88!241.73!BACH1;;chr10:64018918..64018936,+!p2@ZNF365!1.88!75.36!ZNF365;;chr8:22550982..22550999,-!p1@EGR3!1.83!180.05!EGR3;;chr6:106534230..106534254,+!p2@PRDM1!1.81!155.94!PRDM1;;chr2:231084639..231084654,-!p2@SP110!1.79!99.26!SP110;;chr2:157189180..157189290,-!p1@NR4A2!1.78!294.29!NR4A2;;chr1:158979872..158979898,+!p3@IFI16!1.78!174.40!IFI16;;chr2:145277640..145277771,-!p1@ZEB2!1.77!735.18!ZEB2;;chr11:65430554..65430579,-!p3@RELA!1.76!139.87!RELA;;chr14:75988831..75988847,+!p2@BATF!1.74!53.43!BATF;;chr10:31288370..31288393,-!p3@ZNF438!1.73!52.99!ZNF438;;chr22:38597987..38598021,+!p2@MAFF!1.72!299.72!MAFF;;chr12:72056800..72056834,+!p1@THAP2!1.72!67.76!THAP2;;chr11:615942..615957,-!p1@IRF7!1.71!449.15!IRF7;;chr2:231090471..231090504,+!p2@SP140!1.71!49.74!SP140;;chr7:128577972..128578047,+!p1@IRF5!1.70!76.23!IRF5;;chr2:97202480..97202499,+!p1@ARID5A!1.69!456.31!ARID5A;;chr11:47399996..47400014,-!p4@SPI1!1.68!46.91!SPI1;;chr21:30671235..30671253,+!p1@BACH1!1.66!536.67!BACH1;;chr1:25256756..25256774,-!p1@RUNX3!1.66!82.53!RUNX3;;chr11:47400032..47400043,-!p5@SPI1!1.66!44.31!SPI1;;chr1:212782094..212782109,+!p1@ATF3!1.65!1111.14!ATF3;;chr21:36421535..36421610,-!p2@RUNX1!1.64!145.08!RUNX1;;chr3:12329397..12329433,+!p2@PPARG!1.64!95.35!PPARG;;chr2:70142232..70142251,+!p1@MXD1!1.63!224.57!MXD1;;chr19:33793430..33793447,-!p1@CEBPA!1.62!163.33!CEBPA;;chr1:221052733..221052749,+!p2@HLX!1.61!51.26!HLX;;chr12:54778351..54778378,-!p6@ZNF385A!1.61!40.18!ZNF385A;;chr3:12330560..12330579,+!p1@PPARG!1.60!44.74!PPARG;;chr12:72056749..72056767,+!p6@THAP2!1.60!43.00!THAP2;;chr7:50344289..50344323,+!p1@IKZF1!1.60!38.66!IKZF1;;chr10:35484804..35484902,+!p2@CREM!1.59!140.52!CREM;;chr11:65430535..65430549,-!p4@RELA!1.59!44.09!RELA;;chr19:45251395..45251432,+!p8@BCL3!1.59!37.79!BCL3;;chr14:75988771..75988826,+!p1@BATF!1.56!46.70!BATF;;chr9:102584159..102584174,+!p2@NR4A3!1.55!60.81!NR4A3;;chr19:50432132..50432217,+!p2@ATF5!1.55!41.27!ATF5;;chrX:153305787..153305807,-!p3@MECP2!1.55!34.10!MECP2;;chr4:106068026..106068084,+!p1@TET2!1.51!273.22!TET2;;chr13:41593425..41593480,-!p1@ELF1!1.51!191.34!ELF1;;chr12:72056773..72056796,+!p3@THAP2!1.51!40.40!THAP2;;chr21:34398234..34398250,+!p1@OLIG2!1.51!31.06!OLIG2;;chr10:51572408..51572454,+!p3@NCOA4!1.49!168.76!NCOA4;;chr2:145275162..145275202,-!p2@ZEB2!1.49!168.32!ZEB2;;chr16:79634624..79634642,-!p1@MAF!1.49!114.24!MAF;;chr6:126240380..126240430,+!p2@NCOA7!1.49!75.36!NCOA7;;chr17:38497662..38497713,+!p4@RARA!1.48!33.66!RARA;;chr3:187463179..187463201,-!p2@BCL6!1.47!113.81!BCL6;;chr9:110252035..110252057,-!p1@KLF4!1.46!428.30!KLF4;;chr6:15246200..15246214,+!p2@JARID2!1.46!75.36!JARID2;;chr11:47400045..47400060,-!p6@SPI1!1.46!27.80!SPI1;;chr6:106535598..106535637,+!p7@PRDM1!1.45!27.15!PRDM1;;chr12:52445218..52445237,+!p1@NR4A1!1.44!322.31!NR4A1;;chr12:48298765..48298783,-!p2@VDR!1.44!53.86!VDR;;chr21:36260343..36260402,-!p6@RUNX1!1.44!41.70!RUNX1;;chr14:35872453..35872485,-!p2@NFKBIA!1.43!63.20!NFKBIA;;chr6:144385698..144385742,-!p2@PLAGL1!1.43!31.49!PLAGL1;;chr6:391743..391759,+!p1@IRF4!1.43!26.06!IRF4;;chr8:53373491..53373506,-!p4@ST18!1.39!23.67!ST18;;chr20:48599506..48599526,+!p1@SNAI1!1.38!144.43!SNAI1;;chr12:11802753..11802834,+!p2@ETV6!1.38!110.77!ETV6;;chr22:38598057..38598071,+!p3@MAFF!1.38!52.99!MAFF;;chr13:41635029..41635044,-!p4@ELF1!1.38!47.78!ELF1;;chr11:47399920..47399931,-!p7@SPI1!1.38!23.24!SPI1;;chr14:75745523..75745537,+!p1@FOS!1.37!2604.96!FOS;;chr20:48807351..48807384,+!p1@CEBPB!1.37!2176.23!CEBPB;;chr2:61108695..61108753,+!p1@REL!1.37!151.38!REL;;chr18:3449720..3449749,+!p2@TGIF1!1.37!46.70!TGIF1;;chr6:126240463..126240489,+!p6@NCOA7!1.37!24.98!NCOA7;;chr9:129567282..129567353,+!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1:35657108..35657135,-!p5@SFPQ!0.36!3.26!SFPQ;;chr7:28448995..28449011,+!p4@CREB5!0.36!2.17!CREB5;;chr10:3819310..3819325,-!p5@KLF6!0.36!1.95!KLF6;;chr10:124768217..124768228,-!p2@IKZF5!0.36!1.30!IKZF5;;chr10:135121763..135121783,+!p5@ZNF511!0.36!1.30!ZNF511;;chr10:98591737..98591748,+!p12@LCOR!0.36!1.30!LCOR;;chr11:47237987..47237998,+!p5@DDB2!0.36!1.30!DDB2;;chr12:52448293..52448318,+!p10@NR4A1!0.36!1.30!NR4A1;;chr12:52450298..52450331,+!p11@NR4A1!0.36!1.30!NR4A1;;chr12:54694653..54694672,-!p2@NFE2!0.36!1.30!NFE2;;chr12:72056897..72056908,+!p12@THAP2!0.36!1.30!THAP2;;chr6:44233244..44233248,-!p3@NFKBIE!0.36!1.30!NFKBIE;;chr7:28449015..28449024,+!p6@CREB5!0.36!1.30!CREB5;;chr8:116681878..116681893,-!p15@TRPS1!0.36!1.30!TRPS1;;chr8:144512897..144512903,-!p1@MAFA!0.36!1.30!MAFA;;chr19:45974005..45974026,+!p11@FOSB!0.36!1.30!FOSB;;chr19:45977993..45978005,+!p6@FOSB!0.36!1.30!FOSB;;chr19:45978387..45978400,+!p16@FOSB!0.36!1.30!FOSB;;chr19:50922187..50922204,+!p1@SPIB!0.36!1.30!SPIB;;chr19:54058046..54058053,+!p18@ZNF331!0.36!1.30!ZNF331;;chr1:158985667..158985675,+!p31@IFI16!0.36!1.30!IFI16;;chr1:16279391..16279405,-!p3@ZBTB17!0.36!1.30!ZBTB17;;chr1:25256175..25256228,-!p5@RUNX3!0.36!1.30!RUNX3;;chr20:23342623..23342652,+!p2@GZF1!0.36!1.30!GZF1;;chr14:75746781..75746799,+!p6@FOS!0.36!1.30!FOS;;chr17:79881318..79881331,-!p7@MAFG!0.36!1.30!MAFG;;chr17:79881433..79881452,-!p6@MAFG!0.36!1.30!MAFG;;chr18:3449488..3449499,+!p28@TGIF1!0.36!1.30!TGIF1;;chr18:53177984..53178004,-!p17@TCF4!0.36!1.30!TCF4;;chr2:122042770..122042785,-!p1@TFCP2L1!0.36!1.30!TFCP2L1;;chr2:145276113..145276149,-!p28@ZEB2!0.36!1.30!ZEB2;;chr2:70165396..70165410,+!p15@MXD1!0.36!1.30!MXD1;;chr2:70165961..70165981,+!p8@MXD1!0.36!1.30!MXD1;;chr2:97203110..97203159,+!p4@ARID5A!0.36!1.30!ARID5A;;chr3:71630844..71630862,-!p40@FOXP1!0.36!1.30!FOXP1;;chr4:103498623..103498650,+!p9@NFKB1!0.36!1.30!NFKB1;;chr13:20357063..20357105,-!p1@PSPC1!0.35!64.94!PSPC1;;chr18:51750839..51750885,-!p2@MBD2!0.35!19.55!MBD2;;chr3:71632840..71632857,-!p10@FOXP1!0.35!3.26!FOXP1;;chr3:71630690..71630750,-!p11@FOXP1!0.35!2.61!FOXP1;;chr16:67063142..67063153,+!p4@CBFB!0.35!2.17!CBFB;;chr8:80680024..80680046,-!p2@HEY1!0.35!1.52!HEY1;;chr1:161736102..161736123,+!p1@ATF6!0.34!51.69!ATF6;;chr3:52719912..52719995,-!p1@PBRM1!0.34!32.14!PBRM1;;chr12:96588143..96588185,+!p1@ELK3!0.34!23.89!ELK3;;chr12:48744642..48744733,-!p1@ZNF641!0.34!12.81!ZNF641;;chr7:148581360..148581425,-!p1@EZH2!0.34!9.12!EZH2;;chr1:8483878..8483907,-!p4@RERE!0.34!6.95!RERE;;chr2:145275109..145275128,-!p6@ZEB2!0.34!3.69!ZEB2;;chr16:79633894..79633954,-!p3@MAF!0.34!3.04!MAF;;chr15:31619570..31619615,+!p6@KLF13!0.34!2.61!KLF13;;chr9:4299552..4299598,-!p5@GLIS3!0.34!2.61!GLIS3;;chr20:52185447..52185462,-!p2@ZNF217!0.34!2.39!ZNF217;;chr1:23857325..23857416,-!p2@E2F2!0.34!1.52!E2F2;;chr16:88752889..88752921,-!p1@SNAI3!0.34!1.52!SNAI3;;chr5:137804130..137804156,+!p5@EGR1!0.34!1.30!EGR1;;chr6:136610911..136610990,-!p1@BCLAF1!0.33!172.88!BCLAF1;;chr8:37553292..37553317,+!p1@ZNF703!0.33!45.39!ZNF703;;chr3:126194707..126194798,-!p1@ZXDC!0.33!31.28!ZXDC;;chr19:9546177..9546224,-!p1@ZNF266!0.33!13.25!ZNF266;;chr13:41635512..41635539,-!p2@ELF1!0.33!10.21!ELF1;;chr2:28616358..28616380,+!p3@FOSL2!0.33!9.56!FOSL2;;chr16:67063211..67063240,+!p2@CBFB!0.33!8.69!CBFB;;chr3:101395936..101395962,-!p2@ZBTB11!0.33!6.95!ZBTB11;;chr6:35227282..35227330,+!p2@ZNF76!0.33!6.52!ZNF76;;chr2:187350951..187350962,+!p2@ZC3H15!0.33!3.91!ZC3H15;; | |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000222;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000234;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000576;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000763;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000766;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000860;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002193;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002390;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002405 | |||
|ffid_belonging_in_development=CL:0000049,CL:0000134,CL:0002057 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 34: | Line 42: | ||
|fonse_treatment_closure=EFO:0000369,FF:0000625,FF:0000631,FF:0011444,FF:11882-125D1 | |fonse_treatment_closure=EFO:0000369,FF:0000625,FF:0000631,FF:0011444,FF:11882-125D1 | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Trehalose%2520dimycolate%2520%2528TDM%2529%252c%2520donor3.CNhs13544.11882-125D1.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Trehalose%2520dimycolate%2520%2528TDM%2529%252c%2520donor3.CNhs13544.11882-125D1.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Trehalose%2520dimycolate%2520%2528TDM%2529%252c%2520donor3.CNhs13544.11882-125D1.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Trehalose%2520dimycolate%2520%2528TDM%2529%252c%2520donor3.CNhs13544.11882-125D1.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Trehalose%2520dimycolate%2520%2528TDM%2529%252c%2520donor3.CNhs13544.11882-125D1.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11882-125D1 | |id=FF:11882-125D1 | ||
|is_a=EFO:0002091;;FF: | |is_a=EFO:0002091;;FF:0011444 | ||
|is_obsolete= | |||
|library_id=CNhs13544 | |||
|library_id_phase_based=2:CNhs13544 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11882 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11882 | |||
|name=CD14+ monocytes - treated with Trehalose dimycolate (TDM), donor3 | |name=CD14+ monocytes - treated with Trehalose dimycolate (TDM), donor3 | ||
|namespace= | |namespace= | ||
Line 41: | Line 61: | ||
|profile_cagescan=,,, | |profile_cagescan=,,, | ||
|profile_hcage=CNhs13544,LSID1029,release012,COMPLETED | |profile_hcage=CNhs13544,LSID1029,release012,COMPLETED | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq=,,, | |profile_srnaseq=,,, | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0.450184739666965,0.0518671367166023,0,0.0853579634813876,0.557057773781738,0.202001000856042,0,0.336625642684261,-0.146627332728995,0,0.0853579634813876,0.557057773781738,0,0,0,0,0,0,0.0853579634813876,0.271552455695895,0.0853579634813876,0,-0.06796504686704,0,0,0,0.0783317607528795,0,-0.0979578962680575,0,0.450879336282104,-0.132956589778862,0,0,0,0,0,0.121010742493573,0,1.12644845797278,0,0.217896074132256,0,0,-0.0209443828604288,0,0.156663521505759,0,0,0.0426789817406938,0,0,0,-0.0242150211128343,0,0,0,0.0853579634813876,0,-0.0839305477320758,0,0.17456009445329,0,0.727848317790301,-0.0119856637317094,0,1.32352120300975,0,0,0,0.0853579634813876,0.156663521505759,0.0276275064277236,0,0,1.0660370473557,0,0,0.650795127684496,0,0,0,0.0853579634813876,0,0,0,0.101665809062469,0,0,-0.534425360477246,0,0,0,-0.0584468268118252,-0.168518420955175,0.0426789817406938,0,0.990039630550735,0,-0.0126773877563188,-0.138477200800895,0,0,0,0,0,0.86441906957984,0.0853579634813876,0,0,0,0,0,0.217896074132256,0,0,0,0,-0.0180418331695816,0.0853579634813876,0,0,0.0534791837986214,0.0446687649049029,0,0.470513333719778,0.0247689475080989,0,0,0 | |||
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| |||
|rna_box=125 | |rna_box=125 | ||
|rna_catalog_number= | |rna_catalog_number= | ||
Line 56: | Line 79: | ||
|rna_weight_ug=1.949445 | |rna_weight_ug=1.949445 | ||
|sample_age=21 | |sample_age=21 | ||
|sample_category=primary cells | |||
|sample_cell_catalog= | |sample_cell_catalog= | ||
|sample_cell_line= | |sample_cell_line= | ||
Line 68: | Line 92: | ||
|sample_ethnicity= | |sample_ethnicity= | ||
|sample_experimental_condition= | |sample_experimental_condition= | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;2.22654020095198e-268!GO:0005737;cytoplasm;2.27992840348923e-122!GO:0043227;membrane-bound organelle;3.46744145792181e-121!GO:0043231;intracellular membrane-bound organelle;6.9387599778834e-121!GO:0043226;organelle;1.24701261794254e-110!GO:0043229;intracellular organelle;7.81838799380695e-110!GO:0044444;cytoplasmic part;1.485885809988e-80!GO:0044237;cellular metabolic process;4.44945532272945e-70!GO:0044422;organelle part;2.27619621088379e-69!GO:0044238;primary metabolic process;7.40715037328151e-68!GO:0044446;intracellular organelle part;7.40715037328151e-68!GO:0043170;macromolecule metabolic process;2.43454217934488e-67!GO:0005515;protein binding;6.11055799129404e-67!GO:0032991;macromolecular complex;9.60888207914023e-59!GO:0003723;RNA binding;4.54535186427017e-57!GO:0030529;ribonucleoprotein complex;4.75260366728467e-53!GO:0005634;nucleus;1.43949019040969e-51!GO:0044428;nuclear part;1.36305791074685e-47!GO:0019538;protein metabolic process;3.66938355777378e-47!GO:0044267;cellular protein metabolic process;5.21715593633298e-45!GO:0044260;cellular macromolecule metabolic process;8.31369904235027e-45!GO:0033036;macromolecule localization;6.15760199681187e-42!GO:0006412;translation;6.34453886268804e-41!GO:0015031;protein transport;7.06006946592222e-41!GO:0045184;establishment of protein localization;1.15419195946663e-40!GO:0043233;organelle lumen;3.40603382369531e-39!GO:0031974;membrane-enclosed lumen;3.40603382369531e-39!GO:0008104;protein localization;4.44904162340301e-39!GO:0043283;biopolymer metabolic process;5.79956975474853e-38!GO:0010467;gene expression;3.24643002925026e-36!GO:0005829;cytosol;1.08570058413529e-35!GO:0031090;organelle membrane;3.36574691854497e-32!GO:0006396;RNA processing;4.86579397840408e-32!GO:0016071;mRNA metabolic process;1.02340487439609e-31!GO:0006915;apoptosis;1.80222158842971e-31!GO:0012501;programmed cell death;2.36428434964601e-31!GO:0031981;nuclear lumen;6.24646783816921e-30!GO:0008219;cell death;6.61341912204259e-30!GO:0016265;death;6.61341912204259e-30!GO:0009059;macromolecule biosynthetic process;1.14634717074964e-29!GO:0044249;cellular biosynthetic process;3.29433772898062e-29!GO:0043234;protein complex;5.21428039190469e-29!GO:0005739;mitochondrion;1.20540109483911e-28!GO:0008380;RNA splicing;1.98893452366063e-28!GO:0009058;biosynthetic process;2.14954529813537e-28!GO:0005840;ribosome;1.26661112899409e-27!GO:0006397;mRNA processing;1.83273803940127e-27!GO:0046907;intracellular transport;3.00597472913651e-27!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.4832966370987e-27!GO:0006886;intracellular protein transport;5.0017647341465e-27!GO:0031967;organelle envelope;5.76127770248717e-26!GO:0003735;structural constituent of ribosome;1.04905312288522e-25!GO:0031975;envelope;1.10751930213631e-25!GO:0016043;cellular component organization and biogenesis;4.86021632520131e-25!GO:0033279;ribosomal subunit;2.47947938455955e-24!GO:0005830;cytosolic ribosome (sensu Eukaryota);6.17236533080575e-24!GO:0044445;cytosolic part;2.96816818009434e-22!GO:0005681;spliceosome;1.24414506110339e-21!GO:0044429;mitochondrial part;2.47071523412657e-21!GO:0051649;establishment of cellular localization;3.04827772016134e-21!GO:0042981;regulation of apoptosis;4.14037400609458e-21!GO:0005654;nucleoplasm;7.5183572958563e-21!GO:0043067;regulation of programmed cell death;1.08594829901912e-20!GO:0000166;nucleotide binding;1.37288410070587e-20!GO:0051641;cellular localization;1.58786113213652e-20!GO:0065003;macromolecular complex assembly;1.86248689771741e-19!GO:0008134;transcription factor binding;2.91929566065806e-19!GO:0006512;ubiquitin cycle;4.25775114135751e-19!GO:0022613;ribonucleoprotein complex biogenesis and assembly;2.9917181990406e-18!GO:0003676;nucleic acid binding;1.52964501461159e-17!GO:0044265;cellular macromolecule catabolic process;1.53227773885638e-17!GO:0006119;oxidative phosphorylation;1.86952704460171e-17!GO:0016192;vesicle-mediated transport;3.84859896370179e-17!GO:0044451;nucleoplasm part;4.03584195214327e-17!GO:0007243;protein kinase cascade;6.47759028661108e-17!GO:0002376;immune system process;7.90664146501715e-17!GO:0016070;RNA metabolic process;8.76577444037781e-17!GO:0043412;biopolymer modification;2.31655060568603e-16!GO:0048523;negative regulation of cellular process;2.35423253114021e-16!GO:0005740;mitochondrial envelope;2.63080892924917e-16!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;6.07494524385298e-16!GO:0022607;cellular component assembly;6.12921028300774e-16!GO:0016462;pyrophosphatase activity;6.34544064330827e-16!GO:0017111;nucleoside-triphosphatase activity;7.71438432313582e-16!GO:0043285;biopolymer catabolic process;8.04882677907096e-16!GO:0022618;protein-RNA complex assembly;8.30175185967132e-16!GO:0016817;hydrolase activity, acting on acid anhydrides;8.30175185967132e-16!GO:0031966;mitochondrial membrane;9.4924296897203e-16!GO:0050794;regulation of cellular process;1.06953336589124e-15!GO:0048770;pigment granule;1.13329889394597e-15!GO:0042470;melanosome;1.13329889394597e-15!GO:0007249;I-kappaB kinase/NF-kappaB cascade;1.82307288701692e-15!GO:0019866;organelle inner membrane;2.65427326451754e-15!GO:0006464;protein modification process;3.08693424755357e-15!GO:0032553;ribonucleotide binding;4.983889640791e-15!GO:0032555;purine ribonucleotide binding;4.983889640791e-15!GO:0019941;modification-dependent protein catabolic process;6.02197434495305e-15!GO:0043632;modification-dependent macromolecule catabolic process;6.02197434495305e-15!GO:0051603;proteolysis involved in cellular protein catabolic process;7.42457913616452e-15!GO:0043687;post-translational protein modification;7.50586589555199e-15!GO:0044257;cellular protein catabolic process;7.74740233718482e-15!GO:0009057;macromolecule catabolic process;9.34133414284384e-15!GO:0006511;ubiquitin-dependent protein catabolic process;1.25323355221451e-14!GO:0005773;vacuole;1.5725272296197e-14!GO:0048519;negative regulation of biological process;1.70904837581207e-14!GO:0017076;purine nucleotide binding;1.93402931632085e-14!GO:0006955;immune response;3.04633489999069e-14!GO:0007242;intracellular signaling cascade;7.47269311076491e-14!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;8.55877567254951e-14!GO:0016874;ligase activity;9.6806042743173e-14!GO:0006605;protein targeting;1.03851251235286e-13!GO:0044248;cellular catabolic process;2.64562696061557e-13!GO:0000502;proteasome complex (sensu Eukaryota);4.1111048244914e-13!GO:0015934;large ribosomal subunit;4.86779748153047e-13!GO:0043069;negative regulation of programmed cell death;4.9117062055368e-13!GO:0043066;negative regulation of apoptosis;5.45041969430599e-13!GO:0030163;protein catabolic process;5.64430600699283e-13!GO:0000323;lytic vacuole;5.88618302520102e-13!GO:0005764;lysosome;5.88618302520102e-13!GO:0016604;nuclear body;8.07615513585873e-13!GO:0005743;mitochondrial inner membrane;1.10905740753274e-12!GO:0050789;regulation of biological process;1.13566485341105e-12!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.46502114684059e-12!GO:0006950;response to stress;2.69930430265109e-12!GO:0006457;protein folding;2.74205356732296e-12!GO:0006913;nucleocytoplasmic transport;3.122553047258e-12!GO:0015935;small ribosomal subunit;3.13794155181372e-12!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);4.30581301240491e-12!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;4.50805534397336e-12!GO:0044455;mitochondrial membrane part;4.68356469479238e-12!GO:0051169;nuclear transport;5.71633790043737e-12!GO:0008135;translation factor activity, nucleic acid binding;5.83088619680641e-12!GO:0006996;organelle organization and biogenesis;7.07605321011277e-12!GO:0003712;transcription cofactor activity;7.85742150262128e-12!GO:0009615;response to virus;8.33622317502663e-12!GO:0005768;endosome;1.02014487451924e-11!GO:0012505;endomembrane system;1.21736426825322e-11!GO:0006366;transcription from RNA polymerase II promoter;1.33588717846479e-11!GO:0006793;phosphorus metabolic process;1.47637964222874e-11!GO:0006796;phosphate metabolic process;1.47637964222874e-11!GO:0051246;regulation of protein metabolic process;1.60253537006881e-11!GO:0016607;nuclear speck;1.91485384287961e-11!GO:0006259;DNA metabolic process;3.10107698722614e-11!GO:0006413;translational initiation;3.99321526936149e-11!GO:0065009;regulation of a molecular function;4.51897397986236e-11!GO:0003743;translation initiation factor activity;4.78914012825765e-11!GO:0065007;biological regulation;7.87670224725524e-11!GO:0006916;anti-apoptosis;8.56966398508959e-11!GO:0005794;Golgi apparatus;1.01194427769504e-10!GO:0016310;phosphorylation;1.32158364190572e-10!GO:0006446;regulation of translational initiation;1.85456198727042e-10!GO:0005524;ATP binding;3.14297133901975e-10!GO:0051186;cofactor metabolic process;4.80875913963518e-10!GO:0032559;adenyl ribonucleotide binding;4.80875913963518e-10!GO:0031324;negative regulation of cellular metabolic process;4.96108305845444e-10!GO:0051082;unfolded protein binding;7.89624398558921e-10!GO:0048522;positive regulation of cellular process;8.40249195991087e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;8.68790540933009e-10!GO:0005746;mitochondrial respiratory chain;9.89138544537606e-10!GO:0005730;nucleolus;9.98751127902251e-10!GO:0005635;nuclear envelope;1.2749034521556e-09!GO:0030554;adenyl nucleotide binding;1.77621553461301e-09!GO:0008639;small protein conjugating enzyme activity;1.78688692460049e-09!GO:0019787;small conjugating protein ligase activity;2.51414605833349e-09!GO:0004842;ubiquitin-protein ligase activity;2.57610255646202e-09!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;3.12648958893653e-09!GO:0015986;ATP synthesis coupled proton transport;3.3918700597817e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;3.3918700597817e-09!GO:0000398;nuclear mRNA splicing, via spliceosome;3.67240000492332e-09!GO:0000375;RNA splicing, via transesterification reactions;3.67240000492332e-09!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;3.67240000492332e-09!GO:0009967;positive regulation of signal transduction;3.81052505754295e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;3.81052505754295e-09!GO:0006732;coenzyme metabolic process;4.15477627668438e-09!GO:0050136;NADH dehydrogenase (quinone) activity;4.65629244960873e-09!GO:0003954;NADH dehydrogenase activity;4.65629244960873e-09!GO:0008137;NADH dehydrogenase (ubiquinone) activity;4.65629244960873e-09!GO:0048518;positive regulation of biological process;4.65802630591626e-09!GO:0016787;hydrolase activity;5.10786512889426e-09!GO:0043065;positive regulation of apoptosis;6.57251162470755e-09!GO:0005770;late endosome;7.61285283699615e-09!GO:0005783;endoplasmic reticulum;8.48739084562297e-09!GO:0009056;catabolic process;8.58610121869176e-09!GO:0019829;cation-transporting ATPase activity;9.24443871249623e-09!GO:0009607;response to biotic stimulus;9.75254864031829e-09!GO:0043068;positive regulation of programmed cell death;1.06872630619011e-08!GO:0006417;regulation of translation;1.17370103471831e-08!GO:0006163;purine nucleotide metabolic process;1.50616091504239e-08!GO:0009892;negative regulation of metabolic process;1.7144003566545e-08!GO:0006164;purine nucleotide biosynthetic process;1.99282606422653e-08!GO:0042623;ATPase activity, coupled;2.09610405510522e-08!GO:0017038;protein import;2.23568131189734e-08!GO:0009259;ribonucleotide metabolic process;2.37977773250898e-08!GO:0048193;Golgi vesicle transport;2.60072967151774e-08!GO:0009150;purine ribonucleotide metabolic process;2.62258404776596e-08!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.84863461339345e-08!GO:0019222;regulation of metabolic process;3.1691263978614e-08!GO:0009152;purine ribonucleotide biosynthetic process;3.25506815673979e-08!GO:0007049;cell cycle;3.54874445177258e-08!GO:0005525;GTP binding;4.19359562375489e-08!GO:0016887;ATPase activity;4.58882943315344e-08!GO:0006754;ATP biosynthetic process;4.7079041393249e-08!GO:0006753;nucleoside phosphate metabolic process;4.7079041393249e-08!GO:0050790;regulation of catalytic activity;4.74042449954098e-08!GO:0042775;organelle ATP synthesis coupled electron transport;6.01718356334748e-08!GO:0042773;ATP synthesis coupled electron transport;6.01718356334748e-08!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;6.02757449934337e-08!GO:0003924;GTPase activity;6.74356050457423e-08!GO:0009260;ribonucleotide biosynthetic process;6.90306575215263e-08!GO:0044453;nuclear membrane part;6.97633611089906e-08!GO:0016564;transcription repressor activity;7.90625105066911e-08!GO:0016881;acid-amino acid ligase activity;8.35748069202833e-08!GO:0009889;regulation of biosynthetic process;8.45490228689861e-08!GO:0016879;ligase activity, forming carbon-nitrogen bonds;8.93453379563162e-08!GO:0007264;small GTPase mediated signal transduction;8.96543643804683e-08!GO:0051170;nuclear import;1.01504820589112e-07!GO:0031965;nuclear membrane;1.04147565572263e-07!GO:0030964;NADH dehydrogenase complex (quinone);1.11299023444592e-07!GO:0045271;respiratory chain complex I;1.11299023444592e-07!GO:0005747;mitochondrial respiratory chain complex I;1.11299023444592e-07!GO:0008047;enzyme activator activity;1.20634956283642e-07!GO:0016481;negative regulation of transcription;1.33270889512018e-07!GO:0006917;induction of apoptosis;1.44484622270629e-07!GO:0005774;vacuolar membrane;1.49124997792217e-07!GO:0048468;cell development;1.65332962801035e-07!GO:0051726;regulation of cell cycle;1.73276516266471e-07!GO:0008565;protein transporter activity;1.74090943642479e-07!GO:0000074;regulation of progression through cell cycle;1.88762116278224e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;1.94131902010151e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;1.94131902010151e-07!GO:0046034;ATP metabolic process;2.03778836148109e-07!GO:0016469;proton-transporting two-sector ATPase complex;2.047146056526e-07!GO:0009966;regulation of signal transduction;2.07924956917094e-07!GO:0031326;regulation of cellular biosynthetic process;2.16339296319714e-07!GO:0006606;protein import into nucleus;2.23933253863543e-07!GO:0015078;hydrogen ion transmembrane transporter activity;2.23933253863543e-07!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;2.25432278500622e-07!GO:0012502;induction of programmed cell death;2.36909714412647e-07!GO:0003713;transcription coactivator activity;2.52131542270412e-07!GO:0009142;nucleoside triphosphate biosynthetic process;2.67648386644631e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;2.67648386644631e-07!GO:0009055;electron carrier activity;3.75907080297686e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;4.22338387144418e-07!GO:0009144;purine nucleoside triphosphate metabolic process;4.22338387144418e-07!GO:0044440;endosomal part;4.85982851033018e-07!GO:0010008;endosome membrane;4.85982851033018e-07!GO:0009199;ribonucleoside triphosphate metabolic process;5.53344986945285e-07!GO:0006974;response to DNA damage stimulus;5.59463242301907e-07!GO:0051188;cofactor biosynthetic process;5.88352815892958e-07!GO:0050657;nucleic acid transport;6.63653733489739e-07!GO:0051236;establishment of RNA localization;6.63653733489739e-07!GO:0050658;RNA transport;6.63653733489739e-07!GO:0031980;mitochondrial lumen;7.13291666442563e-07!GO:0005759;mitochondrial matrix;7.13291666442563e-07!GO:0045786;negative regulation of progression through cell cycle;7.46132868909609e-07!GO:0044437;vacuolar part;7.60452276676126e-07!GO:0044432;endoplasmic reticulum part;8.47283563797193e-07!GO:0009108;coenzyme biosynthetic process;8.55677687827202e-07!GO:0006403;RNA localization;9.08067615461628e-07!GO:0005765;lysosomal membrane;9.29965914367709e-07!GO:0032561;guanyl ribonucleotide binding;1.11349589481702e-06!GO:0019001;guanyl nucleotide binding;1.11349589481702e-06!GO:0019899;enzyme binding;1.24609827680272e-06!GO:0006752;group transfer coenzyme metabolic process;1.30138886029932e-06!GO:0009141;nucleoside triphosphate metabolic process;1.46018749454761e-06!GO:0005839;proteasome core complex (sensu Eukaryota);1.50282651612741e-06!GO:0004386;helicase activity;1.73960046298388e-06!GO:0008026;ATP-dependent helicase activity;1.76424492196535e-06!GO:0005793;ER-Golgi intermediate compartment;1.82527138383286e-06!GO:0005643;nuclear pore;1.82584343713077e-06!GO:0043228;non-membrane-bound organelle;2.32797253767336e-06!GO:0043232;intracellular non-membrane-bound organelle;2.32797253767336e-06!GO:0031323;regulation of cellular metabolic process;3.7238559283006e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;4.16856501945411e-06!GO:0032446;protein modification by small protein conjugation;4.68750237074781e-06!GO:0016568;chromatin modification;5.36520889778086e-06!GO:0004298;threonine endopeptidase activity;5.44814247492206e-06!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;5.52135506422676e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;6.20968364208219e-06!GO:0016567;protein ubiquitination;7.36933706413066e-06!GO:0030695;GTPase regulator activity;7.84173255845719e-06!GO:0006325;establishment and/or maintenance of chromatin architecture;9.07839381579256e-06!GO:0051028;mRNA transport;9.23155584268474e-06!GO:0042175;nuclear envelope-endoplasmic reticulum network;9.36517945040521e-06!GO:0016563;transcription activator activity;9.64225844505298e-06!GO:0006281;DNA repair;9.6571330057616e-06!GO:0016044;membrane organization and biogenesis;1.00960344984283e-05!GO:0005789;endoplasmic reticulum membrane;1.00960344984283e-05!GO:0031982;vesicle;1.52837404444407e-05!GO:0006461;protein complex assembly;1.53748123610518e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;1.54107264697446e-05!GO:0015399;primary active transmembrane transporter activity;1.54107264697446e-05!GO:0006954;inflammatory response;1.55261970278819e-05!GO:0006323;DNA packaging;1.93836202795227e-05!GO:0031902;late endosome membrane;1.94889750619444e-05!GO:0022402;cell cycle process;2.03894368333218e-05!GO:0003714;transcription corepressor activity;2.08899305260766e-05!GO:0006888;ER to Golgi vesicle-mediated transport;2.11325986185652e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;2.20702484730604e-05!GO:0016197;endosome transport;2.27657437651459e-05!GO:0046930;pore complex;2.85621918953675e-05!GO:0006357;regulation of transcription from RNA polymerase II promoter;2.95655911815781e-05!GO:0048475;coated membrane;3.47384857203731e-05!GO:0030117;membrane coat;3.47384857203731e-05!GO:0030099;myeloid cell differentiation;3.52059190301215e-05!GO:0003724;RNA helicase activity;3.59886909580991e-05!GO:0065002;intracellular protein transport across a membrane;3.7186711906328e-05!GO:0005096;GTPase activator activity;3.99166509654369e-05!GO:0010468;regulation of gene expression;4.88717365594865e-05!GO:0043566;structure-specific DNA binding;4.89357783583846e-05!GO:0051336;regulation of hydrolase activity;4.97663140984806e-05!GO:0008234;cysteine-type peptidase activity;5.05105270898147e-05!GO:0031252;leading edge;5.17029697621728e-05!GO:0045259;proton-transporting ATP synthase complex;5.21695840723065e-05!GO:0006613;cotranslational protein targeting to membrane;5.81937438998882e-05!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;6.30338882415413e-05!GO:0030532;small nuclear ribonucleoprotein complex;6.95432936394624e-05!GO:0051707;response to other organism;7.13496786012411e-05!GO:0005083;small GTPase regulator activity;7.61085266081969e-05!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;7.64330713120092e-05!GO:0051789;response to protein stimulus;7.64892557206087e-05!GO:0006986;response to unfolded protein;7.64892557206087e-05!GO:0031410;cytoplasmic vesicle;8.83225397734915e-05!GO:0009060;aerobic respiration;9.83209546820299e-05!GO:0042254;ribosome biogenesis and assembly;9.83209546820299e-05!GO:0031988;membrane-bound vesicle;0.000110228178486418!GO:0001816;cytokine production;0.000115263392187545!GO:0008632;apoptotic program;0.000125773461121009!GO:0006401;RNA catabolic process;0.000128460910725402!GO:0030120;vesicle coat;0.00013580055188358!GO:0030662;coated vesicle membrane;0.00013580055188358!GO:0003697;single-stranded DNA binding;0.000147875626627214!GO:0051168;nuclear export;0.000162192084789074!GO:0031202;RNA splicing factor activity, transesterification mechanism;0.000204729024565858!GO:0006897;endocytosis;0.000204729024565858!GO:0010324;membrane invagination;0.000204729024565858!GO:0043492;ATPase activity, coupled to movement of substances;0.000207354323368769!GO:0045892;negative regulation of transcription, DNA-dependent;0.000213817353345486!GO:0006350;transcription;0.000226917503995931!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.0002304169087943!GO:0005761;mitochondrial ribosome;0.000234207736910569!GO:0000313;organellar ribosome;0.000234207736910569!GO:0006818;hydrogen transport;0.000259440546180411!GO:0000245;spliceosome assembly;0.000266350137802433!GO:0051276;chromosome organization and biogenesis;0.000270836318535931!GO:0045333;cellular respiration;0.000285670330969266!GO:0051427;hormone receptor binding;0.000299006096579069!GO:0030097;hemopoiesis;0.000299088813817714!GO:0009719;response to endogenous stimulus;0.000299759725200463!GO:0005885;Arp2/3 protein complex;0.000300932845376888!GO:0007034;vacuolar transport;0.000301875251540036!GO:0022890;inorganic cation transmembrane transporter activity;0.000301875251540036!GO:0032940;secretion by cell;0.000309685802714438!GO:0008186;RNA-dependent ATPase activity;0.00032272066287446!GO:0016023;cytoplasmic membrane-bound vesicle;0.000331330611088533!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000335631382548683!GO:0006952;defense response;0.000343592792809807!GO:0004674;protein serine/threonine kinase activity;0.000355945293616432!GO:0015992;proton transport;0.000371656483467033!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000385206018819707!GO:0007041;lysosomal transport;0.000402145285118676!GO:0007050;cell cycle arrest;0.000402145285118676!GO:0005057;receptor signaling protein activity;0.000419145059254077!GO:0000151;ubiquitin ligase complex;0.000435336107443432!GO:0035257;nuclear hormone receptor binding;0.000447739277295114!GO:0009117;nucleotide metabolic process;0.000454842456305301!GO:0046822;regulation of nucleocytoplasmic transport;0.00046519926509367!GO:0005769;early endosome;0.000467858312594008!GO:0006402;mRNA catabolic process;0.000467858312594008!GO:0051338;regulation of transferase activity;0.000474069369400339!GO:0007005;mitochondrion organization and biogenesis;0.000483369066602266!GO:0005798;Golgi-associated vesicle;0.000483745753423207!GO:0007265;Ras protein signal transduction;0.000497496738767377!GO:0009893;positive regulation of metabolic process;0.000519358215541845!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.000523842194033979!GO:0045321;leukocyte activation;0.000604977472169868!GO:0046519;sphingoid metabolic process;0.000617594153255512!GO:0016740;transferase activity;0.000633056905837375!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000671949588375929!GO:0008654;phospholipid biosynthetic process;0.000684001859764243!GO:0043549;regulation of kinase activity;0.000842763143491914!GO:0006399;tRNA metabolic process;0.000856090941503177!GO:0006612;protein targeting to membrane;0.00085688236170877!GO:0004004;ATP-dependent RNA helicase activity;0.000883911332334803!GO:0006672;ceramide metabolic process;0.000945042936986631!GO:0016281;eukaryotic translation initiation factor 4F complex;0.000950267805433461!GO:0007040;lysosome organization and biogenesis;0.000970223394369913!GO:0005667;transcription factor complex;0.00101235672839451!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;0.00101932527926554!GO:0004812;aminoacyl-tRNA ligase activity;0.00101932527926554!GO:0016875;ligase activity, forming carbon-oxygen bonds;0.00101932527926554!GO:0046983;protein dimerization activity;0.00110175457888512!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.00110750409278363!GO:0045859;regulation of protein kinase activity;0.00110880666905553!GO:0016779;nucleotidyltransferase activity;0.00110880666905553!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00114704312439013!GO:0001726;ruffle;0.0011974530534537!GO:0007259;JAK-STAT cascade;0.00121609407016193!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00123343364609559!GO:0044431;Golgi apparatus part;0.00126990283393961!GO:0030149;sphingolipid catabolic process;0.00132100411873976!GO:0003729;mRNA binding;0.00141522439242674!GO:0043038;amino acid activation;0.00142422469882441!GO:0006418;tRNA aminoacylation for protein translation;0.00142422469882441!GO:0043039;tRNA aminoacylation;0.00142422469882441!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00147307709840152!GO:0065004;protein-DNA complex assembly;0.00150118238222828!GO:0043087;regulation of GTPase activity;0.00176788344781567!GO:0005637;nuclear inner membrane;0.0018448197303526!GO:0045893;positive regulation of transcription, DNA-dependent;0.00186180672471261!GO:0006352;transcription initiation;0.0018643551113195!GO:0006919;caspase activation;0.0019017134156271!GO:0051223;regulation of protein transport;0.00191126772821967!GO:0007033;vacuole organization and biogenesis;0.00191767140514432!GO:0005099;Ras GTPase activator activity;0.00198222627368297!GO:0016251;general RNA polymerase II transcription factor activity;0.00207595251363942!GO:0033116;ER-Golgi intermediate compartment membrane;0.00208677084513547!GO:0002521;leukocyte differentiation;0.00217449217258199!GO:0045941;positive regulation of transcription;0.00235907604879379!GO:0033157;regulation of intracellular protein transport;0.00245264933162836!GO:0042306;regulation of protein import into nucleus;0.00245264933162836!GO:0002757;immune response-activating signal transduction;0.00250004975781828!GO:0009611;response to wounding;0.00252977159030736!GO:0031072;heat shock protein binding;0.00256371605187939!GO:0018193;peptidyl-amino acid modification;0.00270268470248992!GO:0016072;rRNA metabolic process;0.00280842361476757!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00288867290587052!GO:0043281;regulation of caspase activity;0.00288867290587052!GO:0006099;tricarboxylic acid cycle;0.00288867290587052!GO:0046356;acetyl-CoA catabolic process;0.00288867290587052!GO:0044262;cellular carbohydrate metabolic process;0.00300784745978822!GO:0005741;mitochondrial outer membrane;0.00311122177078059!GO:0045637;regulation of myeloid cell differentiation;0.00312377207663759!GO:0051090;regulation of transcription factor activity;0.00312810272430719!GO:0002274;myeloid leukocyte activation;0.00320449496744759!GO:0006364;rRNA processing;0.00325370183898549!GO:0004197;cysteine-type endopeptidase activity;0.00349551056122109!GO:0043280;positive regulation of caspase activity;0.00351141325169051!GO:0009165;nucleotide biosynthetic process;0.00361083947514754!GO:0006643;membrane lipid metabolic process;0.00367062039928587!GO:0051187;cofactor catabolic process;0.00373923024788403!GO:0002252;immune effector process;0.00393846497992053!GO:0002520;immune system development;0.00400013080986572!GO:0043021;ribonucleoprotein binding;0.00404809597235342!GO:0031325;positive regulation of cellular metabolic process;0.00436169147630336!GO:0043085;positive regulation of catalytic activity;0.00444402285589645!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.0045451857993841!GO:0043623;cellular protein complex assembly;0.00461685875458351!GO:0003702;RNA polymerase II transcription factor activity;0.00463713296816574!GO:0022415;viral reproductive process;0.00479034795185332!GO:0006351;transcription, DNA-dependent;0.0052049829724166!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.00520515165045862!GO:0032774;RNA biosynthetic process;0.00534185286692365!GO:0002764;immune response-regulating signal transduction;0.00536262738051782!GO:0019221;cytokine and chemokine mediated signaling pathway;0.0053719691049666!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00549527143927128!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00549527143927128!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00549527143927128!GO:0048534;hemopoietic or lymphoid organ development;0.00576070170109186!GO:0060090;molecular adaptor activity;0.00584807051498152!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.0059348177977901!GO:0016301;kinase activity;0.00595981722438203!GO:0045454;cell redox homeostasis;0.00615496452789253!GO:0006891;intra-Golgi vesicle-mediated transport;0.00618394419413898!GO:0006091;generation of precursor metabolites and energy;0.00623790965695632!GO:0019377;glycolipid catabolic process;0.00628395481367236!GO:0006084;acetyl-CoA metabolic process;0.00629949099586413!GO:0042990;regulation of transcription factor import into nucleus;0.00635355910682221!GO:0042991;transcription factor import into nucleus;0.00635355910682221!GO:0045045;secretory pathway;0.00657268346078239!GO:0005813;centrosome;0.00669804260548132!GO:0046966;thyroid hormone receptor binding;0.00720089742810413!GO:0006468;protein amino acid phosphorylation;0.00726520332043716!GO:0003725;double-stranded RNA binding;0.00738731123278036!GO:0016363;nuclear matrix;0.00741710968776301!GO:0030036;actin cytoskeleton organization and biogenesis;0.00743334258840411!GO:0046649;lymphocyte activation;0.00765206385625086!GO:0031901;early endosome membrane;0.00779466953744108!GO:0004185;serine carboxypeptidase activity;0.00786842919898125!GO:0006607;NLS-bearing substrate import into nucleus;0.00816311599903839!GO:0045449;regulation of transcription;0.00817253294325866!GO:0002250;adaptive immune response;0.00873387931420948!GO:0002460;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.00873387931420948!GO:0031968;organelle outer membrane;0.0089486234556809!GO:0009109;coenzyme catabolic process;0.00919096406067138!GO:0048487;beta-tubulin binding;0.00920443554705121!GO:0043433;negative regulation of transcription factor activity;0.00929605513897097!GO:0048471;perinuclear region of cytoplasm;0.00965461871601269!GO:0019867;outer membrane;0.0100157050702632!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0106193041254939!GO:0030693;caspase activity;0.0106193041254939!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0106193041254939!GO:0048500;signal recognition particle;0.0107465168103415!GO:0005484;SNAP receptor activity;0.0108750397201824!GO:0042110;T cell activation;0.0108947264599993!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.0111551219438273!GO:0030218;erythrocyte differentiation;0.0114500339859718!GO:0002429;immune response-activating cell surface receptor signaling pathway;0.0114555355495769!GO:0001775;cell activation;0.0116998500463995!GO:0031625;ubiquitin protein ligase binding;0.0120090361240215!GO:0033367;protein localization in mast cell secretory granule;0.0120090361240215!GO:0033365;protein localization in organelle;0.0120090361240215!GO:0033371;T cell secretory granule organization and biogenesis;0.0120090361240215!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.0120090361240215!GO:0033375;protease localization in T cell secretory granule;0.0120090361240215!GO:0042629;mast cell granule;0.0120090361240215!GO:0033377;maintenance of protein localization in T cell secretory granule;0.0120090361240215!GO:0033364;mast cell secretory granule organization and biogenesis;0.0120090361240215!GO:0033380;granzyme B localization in T cell secretory granule;0.0120090361240215!GO:0033379;maintenance of protease localization in T cell secretory granule;0.0120090361240215!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.0120090361240215!GO:0033368;protease localization in mast cell secretory granule;0.0120090361240215!GO:0033366;protein localization in secretory granule;0.0120090361240215!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.0120090361240215!GO:0033374;protein localization in T cell secretory granule;0.0120090361240215!GO:0003690;double-stranded DNA binding;0.0125539725062512!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.0125539725062512!GO:0000209;protein polyubiquitination;0.0125539725062512!GO:0006611;protein export from nucleus;0.0131693576081884!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0131926305256802!GO:0045047;protein targeting to ER;0.0131926305256802!GO:0032318;regulation of Ras GTPase activity;0.0132836764873409!GO:0002440;production of molecular mediator of immune response;0.0133353812349714!GO:0001817;regulation of cytokine production;0.0135879655250655!GO:0051098;regulation of binding;0.0137841812366863!GO:0046479;glycosphingolipid catabolic process;0.0149321898261851!GO:0032763;regulation of mast cell cytokine production;0.0149884568360289!GO:0032762;mast cell cytokine production;0.0149884568360289!GO:0006458;'de novo' protein folding;0.0150588910831139!GO:0051084;'de novo' posttranslational protein folding;0.0150588910831139!GO:0019882;antigen processing and presentation;0.015231729042684!GO:0000082;G1/S transition of mitotic cell cycle;0.0153502072582244!GO:0030867;rough endoplasmic reticulum membrane;0.0154855199915757!GO:0045792;negative regulation of cell size;0.0155102623788076!GO:0002467;germinal center formation;0.015584962076019!GO:0008383;manganese superoxide dismutase activity;0.0158333002716241!GO:0001315;age-dependent response to reactive oxygen species;0.0158333002716241!GO:0019883;antigen processing and presentation of endogenous antigen;0.0161721220234964!GO:0046466;membrane lipid catabolic process;0.0163214269158405!GO:0019079;viral genome replication;0.0167461008458471!GO:0006333;chromatin assembly or disassembly;0.0167461008458471!GO:0032386;regulation of intracellular transport;0.0167806703670723!GO:0048146;positive regulation of fibroblast proliferation;0.0170045488256098!GO:0000139;Golgi membrane;0.0173074172995782!GO:0000339;RNA cap binding;0.0185522346870854!GO:0019220;regulation of phosphate metabolic process;0.0189462176875275!GO:0051174;regulation of phosphorus metabolic process;0.0189462176875275!GO:0051345;positive regulation of hydrolase activity;0.0191345368207109!GO:0030308;negative regulation of cell growth;0.0191345368207109!GO:0033673;negative regulation of kinase activity;0.019238313250078!GO:0006469;negative regulation of protein kinase activity;0.019238313250078!GO:0043071;positive regulation of non-apoptotic programmed cell death;0.0194652708116943!GO:0005815;microtubule organizing center;0.0195852678907762!GO:0008312;7S RNA binding;0.0197807590882474!GO:0019318;hexose metabolic process;0.0199035857165477!GO:0030127;COPII vesicle coat;0.020309242314467!GO:0012507;ER to Golgi transport vesicle membrane;0.020309242314467!GO:0017091;AU-rich element binding;0.0205065014171349!GO:0050779;RNA destabilization;0.0205065014171349!GO:0000289;poly(A) tail shortening;0.0205065014171349!GO:0001819;positive regulation of cytokine production;0.0208845008868051!GO:0006665;sphingolipid metabolic process;0.0211406454660138!GO:0030521;androgen receptor signaling pathway;0.0211717324020502!GO:0046467;membrane lipid biosynthetic process;0.0213546695874021!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0213969118876973!GO:0008333;endosome to lysosome transport;0.0214230554957403!GO:0030176;integral to endoplasmic reticulum membrane;0.0214230554957403!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0214292041960401!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0214292041960401!GO:0002768;immune response-regulating cell surface receptor signaling pathway;0.0214445686248086!GO:0002237;response to molecule of bacterial origin;0.0215315039109137!GO:0019904;protein domain specific binding;0.0216198749456107!GO:0051348;negative regulation of transferase activity;0.0222567314133699!GO:0030224;monocyte differentiation;0.0223150468883084!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0223364046839694!GO:0043022;ribosome binding;0.0223364046839694!GO:0006650;glycerophospholipid metabolic process;0.0224491141111998!GO:0048144;fibroblast proliferation;0.0225792550330741!GO:0048145;regulation of fibroblast proliferation;0.0225792550330741!GO:0002443;leukocyte mediated immunity;0.0225792550330741!GO:0030134;ER to Golgi transport vesicle;0.022760949927542!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0228265026450656!GO:0019210;kinase inhibitor activity;0.0228879738050176!GO:0006749;glutathione metabolic process;0.022930511672539!GO:0003727;single-stranded RNA binding;0.0233858798079358!GO:0002224;toll-like receptor signaling pathway;0.0234162881233972!GO:0002221;pattern recognition receptor signaling pathway;0.0234162881233972!GO:0051059;NF-kappaB binding;0.0234269117389463!GO:0030663;COPI coated vesicle membrane;0.0235001179326313!GO:0030126;COPI vesicle coat;0.0235001179326313!GO:0030041;actin filament polymerization;0.0238191149515874!GO:0005996;monosaccharide metabolic process;0.0239088999096844!GO:0019843;rRNA binding;0.0239088999096844!GO:0004860;protein kinase inhibitor activity;0.0242055262070952!GO:0030133;transport vesicle;0.0244068516942149!GO:0000278;mitotic cell cycle;0.0244923683776004!GO:0019783;small conjugating protein-specific protease activity;0.0245144511855825!GO:0048002;antigen processing and presentation of peptide antigen;0.024578449061709!GO:0050811;GABA receptor binding;0.0246380473103246!GO:0006414;translational elongation;0.0250700198621306!GO:0051252;regulation of RNA metabolic process;0.0255194375542888!GO:0030518;steroid hormone receptor signaling pathway;0.0257173029710723!GO:0043300;regulation of leukocyte degranulation;0.0258840535942765!GO:0030118;clathrin coat;0.0258977691893305!GO:0030384;phosphoinositide metabolic process;0.0262381834181207!GO:0015036;disulfide oxidoreductase activity;0.0264494109371493!GO:0000785;chromatin;0.0268550943353216!GO:0030503;regulation of cell redox homeostasis;0.0268550943353216!GO:0006260;DNA replication;0.0269205891426805!GO:0030658;transport vesicle membrane;0.0283380916933197!GO:0046979;TAP2 binding;0.0283839899551404!GO:0046977;TAP binding;0.0283839899551404!GO:0046978;TAP1 binding;0.0283839899551404!GO:0005152;interleukin-1 receptor antagonist activity;0.0288659823226992!GO:0030353;fibroblast growth factor receptor antagonist activity;0.0288659823226992!GO:0008139;nuclear localization sequence binding;0.0289525954156108!GO:0042802;identical protein binding;0.0298943920996233!GO:0030137;COPI-coated vesicle;0.029896131811872!GO:0015923;mannosidase activity;0.0300124494356393!GO:0006007;glucose catabolic process;0.0303298909782779!GO:0051092;activation of NF-kappaB transcription factor;0.0306116225760308!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0306777957238357!GO:0002822;regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.;0.0306953399155968!GO:0002819;regulation of adaptive immune response;0.0306953399155968!GO:0004843;ubiquitin-specific protease activity;0.0307124995636399!GO:0005048;signal sequence binding;0.0308197306018351!GO:0008629;induction of apoptosis by intracellular signals;0.0308350920399785!GO:0043621;protein self-association;0.0312123174188705!GO:0030029;actin filament-based process;0.0312174577159868!GO:0051056;regulation of small GTPase mediated signal transduction;0.0314620547970967!GO:0005669;transcription factor TFIID complex;0.0314813727968698!GO:0008637;apoptotic mitochondrial changes;0.031582983902326!GO:0002682;regulation of immune system process;0.0316859609404995!GO:0006405;RNA export from nucleus;0.0316859609404995!GO:0051329;interphase of mitotic cell cycle;0.0317374791396984!GO:0045639;positive regulation of myeloid cell differentiation;0.031778187696193!GO:0004177;aminopeptidase activity;0.0332408517460084!GO:0008361;regulation of cell size;0.0334943609876052!GO:0002684;positive regulation of immune system process;0.0336189166612666!GO:0042613;MHC class II protein complex;0.0336189166612666!GO:0051247;positive regulation of protein metabolic process;0.0339956363402465!GO:0000287;magnesium ion binding;0.0341663364694421!GO:0046578;regulation of Ras protein signal transduction;0.0341737976405758!GO:0008538;proteasome activator activity;0.0343041004789418!GO:0033033;negative regulation of myeloid cell apoptosis;0.0343214771544498!GO:0001803;regulation of type III hypersensitivity;0.0343214771544498!GO:0032733;positive regulation of interleukin-10 production;0.0343214771544498!GO:0033025;regulation of mast cell apoptosis;0.0343214771544498!GO:0001805;positive regulation of type III hypersensitivity;0.0343214771544498!GO:0033023;mast cell homeostasis;0.0343214771544498!GO:0002431;Fc receptor mediated stimulatory signaling pathway;0.0343214771544498!GO:0033032;regulation of myeloid cell apoptosis;0.0343214771544498!GO:0001802;type III hypersensitivity;0.0343214771544498!GO:0033028;myeloid cell apoptosis;0.0343214771544498!GO:0042590;antigen processing and presentation of exogenous peptide antigen via MHC class I;0.0343214771544498!GO:0033026;negative regulation of mast cell apoptosis;0.0343214771544498!GO:0033024;mast cell apoptosis;0.0343214771544498!GO:0032760;positive regulation of tumor necrosis factor production;0.0343690322907378!GO:0030258;lipid modification;0.0344162227451096!GO:0002573;myeloid leukocyte differentiation;0.0345063443940664!GO:0005684;U2-dependent spliceosome;0.0345760391636591!GO:0008270;zinc ion binding;0.0346505674674658!GO:0051101;regulation of DNA binding;0.0349531922182926!GO:0045113;regulation of integrin biosynthetic process;0.0350980425401201!GO:0045112;integrin biosynthetic process;0.0350980425401201!GO:0005070;SH3/SH2 adaptor activity;0.0352416314418047!GO:0000118;histone deacetylase complex;0.0352823021599017!GO:0002444;myeloid leukocyte mediated immunity;0.0359714578316784!GO:0051325;interphase;0.0359743857100181!GO:0030027;lamellipodium;0.0361078131178495!GO:0030100;regulation of endocytosis;0.0363345660005096!GO:0051540;metal cluster binding;0.0368874241307068!GO:0051536;iron-sulfur cluster binding;0.0368874241307068!GO:0050851;antigen receptor-mediated signaling pathway;0.0377357710998107!GO:0000738;DNA catabolic process, exonucleolytic;0.0382892908884!GO:0006354;RNA elongation;0.0383352384434555!GO:0006310;DNA recombination;0.0385007483238785!GO:0006355;regulation of transcription, DNA-dependent;0.038540547298283!GO:0000049;tRNA binding;0.0389383583524038!GO:0045926;negative regulation of growth;0.03933829020754!GO:0051085;chaperone cofactor-dependent protein folding;0.0394292367557044!GO:0017166;vinculin binding;0.039462337937118!GO:0051052;regulation of DNA metabolic process;0.0395890924295664!GO:0019901;protein kinase binding;0.0396472501609554!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0400850602529713!GO:0006465;signal peptide processing;0.0426697502033316!GO:0045576;mast cell activation;0.0429048547920591!GO:0006383;transcription from RNA polymerase III promoter;0.0429095114375827!GO:0006516;glycoprotein catabolic process;0.0429701978627468!GO:0006644;phospholipid metabolic process;0.0430183352663224!GO:0030660;Golgi-associated vesicle membrane;0.0434001262436166!GO:0050778;positive regulation of immune response;0.0434001262436166!GO:0002697;regulation of immune effector process;0.0442056792770932!GO:0005869;dynactin complex;0.0442066730390309!GO:0006261;DNA-dependent DNA replication;0.0442149907974118!GO:0042611;MHC protein complex;0.0448812328340907!GO:0046483;heterocycle metabolic process;0.0451931760824514!GO:0030433;ER-associated protein catabolic process;0.0457465605710416!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0457465605710416!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0457465605710416!GO:0050900;leukocyte migration;0.0457465605710416!GO:0006302;double-strand break repair;0.0458473837724245!GO:0043488;regulation of mRNA stability;0.0458473837724245!GO:0043487;regulation of RNA stability;0.0458473837724245!GO:0015980;energy derivation by oxidation of organic compounds;0.0461733522994726!GO:0008286;insulin receptor signaling pathway;0.0469924739864216!GO:0006689;ganglioside catabolic process;0.0473484515378965!GO:0051087;chaperone binding;0.0477262848860872!GO:0016408;C-acyltransferase activity;0.0479202188223808!GO:0045944;positive regulation of transcription from RNA polymerase II promoter;0.0479340540765896!GO:0030119;AP-type membrane coat adaptor complex;0.0480517971365164!GO:0000165;MAPKKK cascade;0.0484509683819182!GO:0046426;negative regulation of JAK-STAT cascade;0.0485402843816195!GO:0007162;negative regulation of cell adhesion;0.0499787758072664 | |||
|sample_id=11882 | |sample_id=11882 | ||
|sample_note= | |sample_note= | ||
Line 75: | Line 100: | ||
|sample_tissue= | |sample_tissue= | ||
|top_motifs=STAT5{A,B}:6.4778905873;STAT2,4,6:6.18003354626;FOSL2:5.68475478136;NFE2:5.07418563657;NFE2L2:4.92608854988;IRF7:4.81004172826;FOS_FOS{B,L1}_JUN{B,D}:4.73581582326;STAT1,3:4.62069053389;BACH2:4.62043352693;CEBPA,B_DDIT3:4.47472844592;HLF:4.42770105917;IRF1,2:4.19418545682;PAX2:4.02341808358;SREBF1,2:3.93978759112;NFIL3:3.87857229212;SPIB:3.66939531573;NANOG{mouse}:3.46590544287;FOXP3:3.27679368413;EP300:3.18952935985;ETS1,2:3.18640964356;SPI1:3.17019994955;ATF5_CREB3:3.04396449788;ATF4:3.0131838366;ATF6:2.83404035249;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:2.75049993097;RUNX1..3:2.54821383184;CREB1:2.45593627345;NFKB1_REL_RELA:2.43689819303;DMAP1_NCOR{1,2}_SMARC:2.40266324466;NFE2L1:2.35154590997;JUN:2.34461682581;FOXN1:2.28708612509;HSF1,2:2.14592278594;ATF2:2.01978377796;NR1H4:2.01921598157;TGIF1:1.91632007638;ELF1,2,4:1.88756779092;NFATC1..3:1.83632871687;PAX8:1.69628302426;CDX1,2,4:1.69166229746;MAFB:1.66529876111;ALX4:1.43093483608;HIF1A:1.40958194676;XBP1:1.16504370257;ESRRA:1.00530842989;PPARG:1.00308625958;HOX{A5,B5}:0.896510947241;FOXO1,3,4:0.883670602934;PAX3,7:0.877027328195;HMGA1,2:0.847940571652;SRF:0.801737180141;HMX1:0.708658474131;NR6A1:0.703710720642;RBPJ:0.689122985042;TLX2:0.675675639561;PDX1:0.346761146536;RXRA_VDR{dimer}:0.237615033898;AHR_ARNT_ARNT2:0.215820079799;HBP1_HMGB_SSRP1_UBTF:0.215500583079;MEF2{A,B,C,D}:0.177118641754;FOX{D1,D2}:0.127888329344;RFX2..5_RFXANK_RFXAP:0.109526968289;TBP:0.0862365649116;EN1,2:0.0805365195745;ZBTB16:-0.00196934644258;HES1:-0.0189193879791;GLI1..3:-0.0451781266749;NANOG:-0.0637804648499;HOXA9_MEIS1:-0.0673229839486;VSX1,2:-0.0740021941491;IKZF1:-0.124521553361;PRDM1:-0.155040955455;FOX{F1,F2,J1}:-0.192544245967;PAX1,9:-0.247331391485;MYB:-0.248420100651;SMAD1..7,9:-0.351468541445;BPTF:-0.485483116838;TAL1_TCF{3,4,12}:-0.504015233848;GATA4:-0.541670450417;SPZ1:-0.543914764868;POU2F1..3:-0.556445425214;TFCP2:-0.62041605585;SOX2:-0.637678912146;IKZF2:-0.646286281023;EGR1..3:-0.650360042523;OCT4_SOX2{dimer}:-0.651714146448;RFX1:-0.667530554048;ALX1:-0.701986943786;ESR1:-0.702305754454;RORA:-0.717085254571;FOXM1:-0.720459322967;RXR{A,B,G}:-0.7408856019;MZF1:-0.884877899508;NR3C1:-0.903109268723;ZNF238:-0.911223517263;POU5F1:-0.9220143359;REST:-0.955372809262;TEF:-0.956891224557;PAX6:-1.01268772082;RXR{A,B,G}_{NR1H2,PPAR}dimers:-1.08641823173;PRRX1,2:-1.09565679651;HOX{A6,A7,B6,B7}:-1.10321289638;NHLH1,2:-1.1130685305;HNF4A_NR2F1,2:-1.17669786013;DBP:-1.1820967348;TFAP4:-1.30099449882;GATA6:-1.31329431424;PAX4:-1.32652533767;HNF1A:-1.34054429842;PITX1..3:-1.35450354899;NKX3-2:-1.36033088742;SP1:-1.36734696146;MYFfamily:-1.41550026709;FOXA2:-1.49296104248;T:-1.49782392334;NKX2-1,4:-1.53249363383;GZF1:-1.53333921792;NKX2-3_NKX2-5:-1.53583716646;MYBL2:-1.54680819866;MED-1{core}:-1.57461313773;ELK1,4_GABP{A,B1}:-1.64022437706;E2F1..5:-1.65844582205;MAZ:-1.67385863921;FOXD3:-1.68481792687;NKX3-1:-1.69357588298;SOX5:-1.69667639246;MTE{core}:-1.70761806418;PATZ1:-1.71974157644;FOXP1:-1.74753763033;FOXL1:-1.75107963456;BREu{core}:-1.75668355864;ZBTB6:-1.76596853366;ZFP161:-1.78561704767;GTF2A1,2:-1.83213723969;ZEB1:-1.83899788664;PBX1:-1.85057839815;TLX1..3_NFIC{dimer}:-1.864079678;TEAD1:-1.87403757887;NKX6-1,2:-1.88035947205;MTF1:-1.90169372163;TFAP2B:-1.90462713506;MYOD1:-1.91596758743;SOX{8,9,10}:-1.92372476803;NKX2-2,8:-1.93301225368;GTF2I:-1.94026561365;NFIX:-1.9436964971;TFDP1:-1.9467777022;NFY{A,B,C}:-1.96732226117;ZNF384:-1.9741130265;CUX2:-1.99954590224;TP53:-2.00023871472;bHLH_family:-2.0287643705;SNAI1..3:-2.05498146476;GFI1B:-2.09230535503;CRX:-2.1006812634;ZNF148:-2.11465644708;XCPE1{core}:-2.12179443406;RREB1:-2.1708848995;POU1F1:-2.20559867105;FOX{I1,J2}:-2.23430108284;GCM1,2:-2.23772564304;HOX{A4,D4}:-2.27839766419;KLF4:-2.28531811769;ADNP_IRX_SIX_ZHX:-2.36492436375;POU6F1:-2.4415709138;NR5A1,2:-2.44963770794;TFAP2{A,C}:-2.45325138394;ZIC1..3:-2.45648304246;HIC1:-2.50765496035;FOXQ1:-2.51884688272;AIRE:-2.5336462081;EBF1:-2.58618125974;TBX4,5:-2.59811245558;POU3F1..4:-2.6851618924;UFEwm:-2.70009674542;PAX5:-2.7235714827;LMO2:-2.74412163745;SOX17:-2.80132367263;NRF1:-2.81770113123;GFI1:-2.85381813876;YY1:-2.92227237643;CDC5L:-3.03996837192;EVI1:-3.04544475684;ONECUT1,2:-3.05086252764;TOPORS:-3.14312602983;HAND1,2:-3.15728499315;ARID5B:-3.19576223013;AR:-3.29502608571;ZNF423:-3.43113006672;ZNF143:-3.44537929126;LHX3,4:-3.57740578857;LEF1_TCF7_TCF7L1,2:-3.76420964446 | |top_motifs=STAT5{A,B}:6.4778905873;STAT2,4,6:6.18003354626;FOSL2:5.68475478136;NFE2:5.07418563657;NFE2L2:4.92608854988;IRF7:4.81004172826;FOS_FOS{B,L1}_JUN{B,D}:4.73581582326;STAT1,3:4.62069053389;BACH2:4.62043352693;CEBPA,B_DDIT3:4.47472844592;HLF:4.42770105917;IRF1,2:4.19418545682;PAX2:4.02341808358;SREBF1,2:3.93978759112;NFIL3:3.87857229212;SPIB:3.66939531573;NANOG{mouse}:3.46590544287;FOXP3:3.27679368413;EP300:3.18952935985;ETS1,2:3.18640964356;SPI1:3.17019994955;ATF5_CREB3:3.04396449788;ATF4:3.0131838366;ATF6:2.83404035249;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:2.75049993097;RUNX1..3:2.54821383184;CREB1:2.45593627345;NFKB1_REL_RELA:2.43689819303;DMAP1_NCOR{1,2}_SMARC:2.40266324466;NFE2L1:2.35154590997;JUN:2.34461682581;FOXN1:2.28708612509;HSF1,2:2.14592278594;ATF2:2.01978377796;NR1H4:2.01921598157;TGIF1:1.91632007638;ELF1,2,4:1.88756779092;NFATC1..3:1.83632871687;PAX8:1.69628302426;CDX1,2,4:1.69166229746;MAFB:1.66529876111;ALX4:1.43093483608;HIF1A:1.40958194676;XBP1:1.16504370257;ESRRA:1.00530842989;PPARG:1.00308625958;HOX{A5,B5}:0.896510947241;FOXO1,3,4:0.883670602934;PAX3,7:0.877027328195;HMGA1,2:0.847940571652;SRF:0.801737180141;HMX1:0.708658474131;NR6A1:0.703710720642;RBPJ:0.689122985042;TLX2:0.675675639561;PDX1:0.346761146536;RXRA_VDR{dimer}:0.237615033898;AHR_ARNT_ARNT2:0.215820079799;HBP1_HMGB_SSRP1_UBTF:0.215500583079;MEF2{A,B,C,D}:0.177118641754;FOX{D1,D2}:0.127888329344;RFX2..5_RFXANK_RFXAP:0.109526968289;TBP:0.0862365649116;EN1,2:0.0805365195745;ZBTB16:-0.00196934644258;HES1:-0.0189193879791;GLI1..3:-0.0451781266749;NANOG:-0.0637804648499;HOXA9_MEIS1:-0.0673229839486;VSX1,2:-0.0740021941491;IKZF1:-0.124521553361;PRDM1:-0.155040955455;FOX{F1,F2,J1}:-0.192544245967;PAX1,9:-0.247331391485;MYB:-0.248420100651;SMAD1..7,9:-0.351468541445;BPTF:-0.485483116838;TAL1_TCF{3,4,12}:-0.504015233848;GATA4:-0.541670450417;SPZ1:-0.543914764868;POU2F1..3:-0.556445425214;TFCP2:-0.62041605585;SOX2:-0.637678912146;IKZF2:-0.646286281023;EGR1..3:-0.650360042523;OCT4_SOX2{dimer}:-0.651714146448;RFX1:-0.667530554048;ALX1:-0.701986943786;ESR1:-0.702305754454;RORA:-0.717085254571;FOXM1:-0.720459322967;RXR{A,B,G}:-0.7408856019;MZF1:-0.884877899508;NR3C1:-0.903109268723;ZNF238:-0.911223517263;POU5F1:-0.9220143359;REST:-0.955372809262;TEF:-0.956891224557;PAX6:-1.01268772082;RXR{A,B,G}_{NR1H2,PPAR}dimers:-1.08641823173;PRRX1,2:-1.09565679651;HOX{A6,A7,B6,B7}:-1.10321289638;NHLH1,2:-1.1130685305;HNF4A_NR2F1,2:-1.17669786013;DBP:-1.1820967348;TFAP4:-1.30099449882;GATA6:-1.31329431424;PAX4:-1.32652533767;HNF1A:-1.34054429842;PITX1..3:-1.35450354899;NKX3-2:-1.36033088742;SP1:-1.36734696146;MYFfamily:-1.41550026709;FOXA2:-1.49296104248;T:-1.49782392334;NKX2-1,4:-1.53249363383;GZF1:-1.53333921792;NKX2-3_NKX2-5:-1.53583716646;MYBL2:-1.54680819866;MED-1{core}:-1.57461313773;ELK1,4_GABP{A,B1}:-1.64022437706;E2F1..5:-1.65844582205;MAZ:-1.67385863921;FOXD3:-1.68481792687;NKX3-1:-1.69357588298;SOX5:-1.69667639246;MTE{core}:-1.70761806418;PATZ1:-1.71974157644;FOXP1:-1.74753763033;FOXL1:-1.75107963456;BREu{core}:-1.75668355864;ZBTB6:-1.76596853366;ZFP161:-1.78561704767;GTF2A1,2:-1.83213723969;ZEB1:-1.83899788664;PBX1:-1.85057839815;TLX1..3_NFIC{dimer}:-1.864079678;TEAD1:-1.87403757887;NKX6-1,2:-1.88035947205;MTF1:-1.90169372163;TFAP2B:-1.90462713506;MYOD1:-1.91596758743;SOX{8,9,10}:-1.92372476803;NKX2-2,8:-1.93301225368;GTF2I:-1.94026561365;NFIX:-1.9436964971;TFDP1:-1.9467777022;NFY{A,B,C}:-1.96732226117;ZNF384:-1.9741130265;CUX2:-1.99954590224;TP53:-2.00023871472;bHLH_family:-2.0287643705;SNAI1..3:-2.05498146476;GFI1B:-2.09230535503;CRX:-2.1006812634;ZNF148:-2.11465644708;XCPE1{core}:-2.12179443406;RREB1:-2.1708848995;POU1F1:-2.20559867105;FOX{I1,J2}:-2.23430108284;GCM1,2:-2.23772564304;HOX{A4,D4}:-2.27839766419;KLF4:-2.28531811769;ADNP_IRX_SIX_ZHX:-2.36492436375;POU6F1:-2.4415709138;NR5A1,2:-2.44963770794;TFAP2{A,C}:-2.45325138394;ZIC1..3:-2.45648304246;HIC1:-2.50765496035;FOXQ1:-2.51884688272;AIRE:-2.5336462081;EBF1:-2.58618125974;TBX4,5:-2.59811245558;POU3F1..4:-2.6851618924;UFEwm:-2.70009674542;PAX5:-2.7235714827;LMO2:-2.74412163745;SOX17:-2.80132367263;NRF1:-2.81770113123;GFI1:-2.85381813876;YY1:-2.92227237643;CDC5L:-3.03996837192;EVI1:-3.04544475684;ONECUT1,2:-3.05086252764;TOPORS:-3.14312602983;HAND1,2:-3.15728499315;ARID5B:-3.19576223013;AR:-3.29502608571;ZNF423:-3.43113006672;ZNF143:-3.44537929126;LHX3,4:-3.57740578857;LEF1_TCF7_TCF7L1,2:-3.76420964446 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11882-125D1;search_select_hide=table117:FF:11882-125D1 | |||
}} | }} |
Latest revision as of 18:26, 4 June 2020
Name: | CD14+ monocytes - treated with Trehalose dimycolate (TDM), donor3 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13544 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13544
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13544
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0925 |
10 | 10 | 0.0203 |
100 | 100 | 0.903 |
101 | 101 | 0.753 |
102 | 102 | 0.96 |
103 | 103 | 0.345 |
104 | 104 | 0.53 |
105 | 105 | 0.152 |
106 | 106 | 0.0016 |
107 | 107 | 0.381 |
108 | 108 | 0.7 |
109 | 109 | 0.225 |
11 | 11 | 0.199 |
110 | 110 | 0.131 |
111 | 111 | 0.073 |
112 | 112 | 0.363 |
113 | 113 | 0.591 |
114 | 114 | 0.0244 |
115 | 115 | 0.197 |
116 | 116 | 0.927 |
117 | 117 | 0.0687 |
118 | 118 | 0.204 |
119 | 119 | 0.181 |
12 | 12 | 0.293 |
120 | 120 | 0.481 |
121 | 121 | 0.408 |
122 | 122 | 0.546 |
123 | 123 | 0.518 |
124 | 124 | 0.868 |
125 | 125 | 0.47 |
126 | 126 | 0.213 |
127 | 127 | 0.42 |
128 | 128 | 0.0609 |
129 | 129 | 0.458 |
13 | 13 | 0.0766 |
130 | 130 | 0.268 |
131 | 131 | 0.988 |
132 | 132 | 0.0496 |
133 | 133 | 0.803 |
134 | 134 | 0.734 |
135 | 135 | 0.522 |
136 | 136 | 0.993 |
137 | 137 | 0.013 |
138 | 138 | 0.306 |
139 | 139 | 0.0861 |
14 | 14 | 0.491 |
140 | 140 | 0.498 |
141 | 141 | 0.26 |
142 | 142 | 0.0663 |
143 | 143 | 0.0323 |
144 | 144 | 0.724 |
145 | 145 | 0.414 |
146 | 146 | 0.737 |
147 | 147 | 0.512 |
148 | 148 | 0.0261 |
149 | 149 | 0.884 |
15 | 15 | 0.161 |
150 | 150 | 0.419 |
151 | 151 | 0.381 |
152 | 152 | 0.292 |
153 | 153 | 0.899 |
154 | 154 | 0.609 |
155 | 155 | 0.816 |
156 | 156 | 0.39 |
157 | 157 | 0.753 |
158 | 158 | 0.0364 |
159 | 159 | 0.168 |
16 | 16 | 0.358 |
160 | 160 | 0.511 |
161 | 161 | 0.527 |
162 | 162 | 0.159 |
163 | 163 | 0.161 |
164 | 164 | 0.15 |
165 | 165 | 0.195 |
166 | 166 | 0.523 |
167 | 167 | 0.156 |
168 | 168 | 0.165 |
169 | 169 | 0.0121 |
17 | 17 | 0.324 |
18 | 18 | 0.187 |
19 | 19 | 0.491 |
2 | 2 | 0.511 |
20 | 20 | 0.243 |
21 | 21 | 0.655 |
22 | 22 | 0.287 |
23 | 23 | 0.0597 |
24 | 24 | 0.293 |
25 | 25 | 0.329 |
26 | 26 | 0.0716 |
27 | 27 | 0.651 |
28 | 28 | 0.448 |
29 | 29 | 0.192 |
3 | 3 | 0.194 |
30 | 30 | 0.509 |
31 | 31 | 0.821 |
32 | 32 | 0.507 |
33 | 33 | 0.232 |
34 | 34 | 0.716 |
35 | 35 | 0.198 |
36 | 36 | 0.0808 |
37 | 37 | 0.0699 |
38 | 38 | 0.443 |
39 | 39 | 0.971 |
4 | 4 | 0.845 |
40 | 40 | 0.206 |
41 | 41 | 0.0121 |
42 | 42 | 0.429 |
43 | 43 | 0.0314 |
44 | 44 | 0.769 |
45 | 45 | 0.87 |
46 | 46 | 0.212 |
47 | 47 | 0.609 |
48 | 48 | 0.535 |
49 | 49 | 0.171 |
5 | 5 | 0.267 |
50 | 50 | 0.891 |
51 | 51 | 0.503 |
52 | 52 | 0.481 |
53 | 53 | 0.605 |
54 | 54 | 0.427 |
55 | 55 | 0.71 |
56 | 56 | 0.764 |
57 | 57 | 0.946 |
58 | 58 | 0.163 |
59 | 59 | 0.375 |
6 | 6 | 0.837 |
60 | 60 | 0.0696 |
61 | 61 | 0.782 |
62 | 62 | 0.0796 |
63 | 63 | 0.647 |
64 | 64 | 0.434 |
65 | 65 | 0.298 |
66 | 66 | 0.373 |
67 | 67 | 0.56 |
68 | 68 | 0.937 |
69 | 69 | 0.452 |
7 | 7 | 0.245 |
70 | 70 | 0.0538 |
71 | 71 | 0.0307 |
72 | 72 | 0.171 |
73 | 73 | 0.168 |
74 | 74 | 0.0875 |
75 | 75 | 0.116 |
76 | 76 | 0.229 |
77 | 77 | 0.697 |
78 | 78 | 0.114 |
79 | 79 | 0.733 |
8 | 8 | 0.504 |
80 | 80 | 0.151 |
81 | 81 | 0.408 |
82 | 82 | 0.29 |
83 | 83 | 0.00571 |
84 | 84 | 0.42 |
85 | 85 | 0.0405 |
86 | 86 | 0.0582 |
87 | 87 | 0.493 |
88 | 88 | 0.587 |
89 | 89 | 0.232 |
9 | 9 | 0.452 |
90 | 90 | 0.101 |
91 | 91 | 0.312 |
92 | 92 | 0.317 |
93 | 93 | 0.244 |
94 | 94 | 0.0739 |
95 | 95 | 0.337 |
96 | 96 | 0.619 |
97 | 97 | 0.714 |
98 | 98 | 0.194 |
99 | 99 | 0.0282 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13544
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0011444 CD14-positive monocytes - treated with Trehalose dimycolate (TDM) sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000766 (myeloid leukocyte)
0000219 (motile cell)
0000325 (stuff accumulating cell)
0000473 (defensive cell)
0000234 (phagocyte)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0000255 (eukaryotic cell)
0000576 (monocyte)
0000860 (classical monocyte)
0002057 (CD14-positive, CD16-negative classical monocyte)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
0000625 (experimental infection sample)
0000350 (experimentally modified sample)
0000631 (trehalose dimycolate (TDM) treatment sample)
0011444 (CD14-positive monocytes - treated with Trehalose dimycolate (TDM) sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)
CL:0002057 (CD14-positive, CD16-negative classical monocyte)