FF:10437-106E5: Difference between revisions
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{{f5samples | {{f5samples | ||
|ancestors_in_anatomy_facet=UBERON: | |DRA_sample_Accession=CAGE@SAMD00005103 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |accession_numbers=CAGE;DRX007981;DRR008853;DRZ000278;DRZ001663;DRZ011628;DRZ013013 | ||
|ancestors_in_disease_facet=DOID: | |ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0002046,UBERON:0004119,UBERON:0010314,UBERON:0000062,UBERON:0000061,UBERON:0000465,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0002368,UBERON:0002530,UBERON:0010317,UBERON:0000949 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0000066,CL:0000255 | |||
|ancestors_in_disease_facet=DOID:4,DOID:162,DOID:14566,DOID:0050687,DOID:7,DOID:305,DOID:299,DOID:3112 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100297,FF:0101120,FF:0103209,FF:0101610,FF:0104965 | |||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
|expression_enrichment_score | |||
|fonse_cell_line=FF:0101120,FF:0101610 | |fonse_cell_line=FF:0101120,FF:0101610 | ||
|fonse_cell_line_closure=FF:0101120,FF:0101610 | |fonse_cell_line_closure=FF:0101120,FF:0101610 | ||
| Line 35: | Line 41: | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/papillary%2520adenocarcinoma%2520cell%2520line%253a8505C.CNhs11716.10437-106E5.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/papillary%2520adenocarcinoma%2520cell%2520line%253a8505C.CNhs11716.10437-106E5.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/papillary%2520adenocarcinoma%2520cell%2520line%253a8505C.CNhs11716.10437-106E5.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/papillary%2520adenocarcinoma%2520cell%2520line%253a8505C.CNhs11716.10437-106E5.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/papillary%2520adenocarcinoma%2520cell%2520line%253a8505C.CNhs11716.10437-106E5.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10437-106E5 | |id=FF:10437-106E5 | ||
|is_a=DOID:3112;;EFO:0002091;;FF: | |is_a=DOID:3112;;EFO:0002091;;FF:0000210;;FF:0104965 | ||
|is_obsolete= | |||
|library_id=CNhs11716 | |||
|library_id_phase_based=2:CNhs11716 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10437 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10437 | |||
|name=papillary adenocarcinoma cell line:8505C | |name=papillary adenocarcinoma cell line:8505C | ||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
| Line 42: | Line 60: | ||
|profile_cagescan=,,, | |profile_cagescan=,,, | ||
|profile_hcage=CNhs11716,LSID819,release009,COMPLETED | |profile_hcage=CNhs11716,LSID819,release009,COMPLETED | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq=,,, | |profile_srnaseq=,,, | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,0.260910526402173,0,-0.0585411288815687,0.00657903851914455,0,0,0,0,0,0,0,0,0,0,0,0.218821003311945,0,-0.0874551371417926,0,0,0,0,0,0.199284106797516,0,0,-0.00990771954092778,0,0,0,0,0,0,0,0,0,0,0.259799173661759,0,-0.107883042071201,0.173569605266192,0,0,0,0,0,0,0,0.205414133795601,0,0,0,0,0,0,0.065867873206635,-0.0311244880359701,0,0,-0.0314757540064619,0,0,0,0,0,0,0,0,0.065867873206635,0,0.065867873206635,0,0,0,0,0,0,0.0940054409708498,0.0329339366033175,0,0.0369078804487231,0,0,0,-0.00576544956611513,0.0329339366033175,0,0,0.0450296308228733,-0.0293749308581007,0.0329339366033175,0.123048870237934,0.0329339366033175,0,0.120785652074239,0.201465672998682,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0233451453139523,0.297242003065574,0,0,-0.0885844621415965,-0.255207919571759,0,0,0.0983357224326992,0,0,0 | |||
|repeat_enrich_byname=0,0.173569605266192,0,0,0.120785652074239,0.065867873206635,0,0,0.065867873206635,0,0.065867873206635,0,0,0.123048870237934,0,0,0.146211561324671,0,-0.474086218752008,-0.143515142523472,0.086784802633096,0,-0.013206481266564,0.065867873206635,0.065867873206635,0,0.0403838302987272,0,0,0,0,0,-0.128119866952565,0,-0.0504125515893149,0.0329339366033175,0,0,0,0.239952389000916,-0.305472230898407,0,0.114724537946576,0.449221994824464,0,0,0,0,-0.0104414956725656,0,-0.120879483793741,-0.0827201683234173,-0.0531235150626049,-0.258042486771432,0.010155376425453,0,0,0,0.0335277593771687,-0.223145512844845,0,0,-0.121779851751874,0.133127059058816,0,0,-0.391044581551635,0,-0.0426344551524986,-0.0203473889949408,0,0.211713357470439,0,0,0,0,0,0,0,0.123048870237934,0.517566255901832,0,0,-0.0574934668214365,0.287029277713549,0.0561986457061951,0.173569605266192,0.331711352173375,0,-0.0515903041490899,0,0,0.0479424005319921,-0.146583106246926,-0.118745206498994,0.177132725517836,0,-0.302389727009913,0.00597226046539875,0.104668984760585,0.162927820413214,-0.147401849371139,-0.0669328493119128,0,0.0438391118015289,-0.108049880077873,-0.042375135141322,-0.0961260371779429,-0.0572925961576795,-0.203547707260171,0.192757007078406,0.065867873206635,0.065867873206635,0,-0.0722505321585684,0,0.200135281342825,-0.0427254685177392,-0.065667068710262,0.0383361560594242,0.0298271242329347,-0.147986508341577,0.0337887230150191,0.0801862107797428,-0.0937915092210586,-0.0166585310515394,-0.00515288605146801,0,0,-0.0362418658139174,0.0206177037903655,0.363361008736122,0.167858020750526,0,-0.360928591573046,-0.0683442610773682,0.0329339366033175,-0.208737485581601,-0.214105133967458,0,0,-0.157548674382853,0,0,0.126475245692508,0,0,0.202279112148675,0.107813573282503,-0.16698768834891,0,0.0232435882029436,0.050417207840997,-0.00830348125650005,0,-0.10979783411427,0,0,-0.202711216858405,0,-0.0357942449798485,-0.249272622989079,0.00509360331392272,-0.0587498617162013,0.00742104639480982,0.128265694689497,-0.130415453558153,0.0450296308228733,-0.00525567086102141,-0.0172218203880459,-0.0881268324752877,0,0.294982855180325,-0.18408772066681,-0.0316607813715022,-0.0121718405958803,0,0.0527664792165141,0,-0.012471120923474,0,0.0594173274384813,0.106871964839429,-0.142047371515113,0.0275612661249993,0,-0.1104428388082,-0.456419585600599,0,0,0,0.173569605266192,-0.150367083334639,-0.066715318018154,-0.0154551235755208,0.229543915636032,0,0.0485038078332453,0,0,-0.0870214730045005,0.39550461073004,0.065867873206635,0.201832896893445,0.208246442595454,0.00980183319722372,0.00707779680300043,0.065867873206635,0,-0.57983246478609,0.00440183185191256,0,0.341557223334639,0.00226302806883334,-0.00576544956611513,-0.187458468280121,0,-0.0470983743352884,0,0,0.119714237100398,0,0.0172069973472055,0,0.173569605266192,0.070426266471059,-0.116628112990133,0,0,0.065867873206635,0.0153485876865152,0.065867873206635,0,0,0,0,0,0,0.00966984724845843,0.066395226272111,0,-0.0976287407020897,0,0.123048870237934,0,0,0.517566255901832,0.0196556137075601,0,0,0.687901142558208,0.0104752103339075,0.0505521895897713,0.065867873206635,0,0,0,0.23166584340556,0.0940054409708498,0.123048870237934,-0.131862706497632,0,0,0,0,0.0369078804487231,0,0,0.0329339366033175,0.0329339366033175,0.00813741615297102,-0.130039710307539,0,0,0,0.337063472790728,0,0,0.173569605266192,0,-0.256556257862586,0,0.065867873206635,0.273444288348338,0,-0.0631841372098116,0.0919877257193501,0,-0.258968703439698,-0.307222934801551,0.515392129500831,0,0,-0.0425261284779422,0,0.065867873206635,-0.130569859898529,0.0406786472722682,0.065867873206635,0.0120091606572006,0,0,0,0,0.297242003065574,0,0.082927490665818,0,0,0.00737002369470008,0,0,0.065867873206635,0,0.123048870237934,0,0,0,0.0710032006117105,-0.0263561834518754,0.109509934749083,0,0,0,0,0,0.065867873206635,0.141749653007784,0.187835853205541,0,0,0,0,0,0.065867873206635,0,0,0.106539258528931,0,0,0,0,0,-0.0311244880359701,0,0.065867873206635,0,0,0.0131580770382891,0,0,-0.0585411288815687,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0955019172764976,-0.26845976095221,0,0,0,0,0,0,0,-0.0150341245443317,0,0,0,0,-0.0480165005023422,0,0,0,0.509221489603362,0,0.260910526402173,0,0,0,0,0,0,0.109410501655973,0,0,0,0,0,0,0,0,0,0,0.223694622979517,0,0,0,0.246315772019805,0.0329339366033175,-0.242417745486054,-0.0202800454796719,0,0,-0.066772676546354,0,0,0,0,0,0,0.0780700776274455,0,0,0,0,0,0,0,0.0329339366033175,0,0,0,0,0,0,0,0,0,0,0.297242003065574,0,0,0,0,0,0.0329339366033175,0.0987093364328715,0,0,0,0,0.065867873206635,0,0,0.199284106797516,0,0,0.106756802889479,0,0,0,0,0,0,-0.0642822176771922,0.350403976906377,-0.12500302671961,0,0,0.065867873206635,0.0400727992398297,0,0,0,0.065867873206635,-0.0667773874189013,0,0,0,0,0,0,0,0,0.297242003065574,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0874551371417926,0,0,0,0,0,0,0,0,0,0,0,0,0.109410501655973,0,0,0,0,0,0,0.165855676086687,0,0.0329339366033175,0,0,0,0,0,0.123048870237934,0.0944583717222845,0,0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| |||
|rna_box=106 | |rna_box=106 | ||
|rna_catalog_number= | |rna_catalog_number= | ||
| Line 54: | Line 75: | ||
|rna_rin= | |rna_rin= | ||
|rna_sample_type=total RNA | |rna_sample_type=total RNA | ||
|rna_tube_id= | |rna_tube_id=1.06E+07 | ||
|rna_weight_ug=22.55825 | |rna_weight_ug=22.55825 | ||
|sample_age= | |sample_age= | ||
|sample_category=cell lines | |||
|sample_cell_catalog=RCB2103 | |sample_cell_catalog=RCB2103 | ||
|sample_cell_line=8505C | |sample_cell_line=8505C | ||
| Line 69: | Line 91: | ||
|sample_ethnicity= | |sample_ethnicity= | ||
|sample_experimental_condition= | |sample_experimental_condition= | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;4.10312222284811e-241!GO:0043226;organelle;6.94923261700298e-199!GO:0043229;intracellular organelle;2.5505680738476e-198!GO:0043231;intracellular membrane-bound organelle;5.58730964386658e-196!GO:0043227;membrane-bound organelle;5.58730964386658e-196!GO:0005737;cytoplasm;7.28673767380492e-181!GO:0044422;organelle part;1.02253198927004e-150!GO:0044446;intracellular organelle part;5.11138341407257e-149!GO:0044444;cytoplasmic part;1.83960122626409e-127!GO:0032991;macromolecular complex;6.25508929254965e-108!GO:0005515;protein binding;6.13132087470052e-91!GO:0030529;ribonucleoprotein complex;1.34375312977105e-89!GO:0044238;primary metabolic process;1.29076571195089e-87!GO:0044237;cellular metabolic process;7.0056123528936e-87!GO:0005634;nucleus;1.50601857625373e-84!GO:0043170;macromolecule metabolic process;7.68930336642897e-82!GO:0044428;nuclear part;8.67743942206006e-81!GO:0043233;organelle lumen;4.14100082525798e-77!GO:0031974;membrane-enclosed lumen;4.14100082525798e-77!GO:0003723;RNA binding;4.23551867545646e-72!GO:0005739;mitochondrion;4.52011519269971e-67!GO:0016043;cellular component organization and biogenesis;1.3027875930619e-55!GO:0043234;protein complex;3.25931481373262e-55!GO:0006412;translation;2.47865285749257e-53!GO:0006396;RNA processing;3.32980514328425e-53!GO:0005840;ribosome;9.42414871360878e-53!GO:0019538;protein metabolic process;1.2871923564798e-51!GO:0031090;organelle membrane;1.09158252820555e-47!GO:0031981;nuclear lumen;1.20436810280251e-47!GO:0043283;biopolymer metabolic process;6.6293529294228e-47!GO:0044267;cellular protein metabolic process;1.16967768841881e-46!GO:0044260;cellular macromolecule metabolic process;1.6468854470713e-46!GO:0003735;structural constituent of ribosome;7.72724384712506e-46!GO:0033036;macromolecule localization;2.12103028451424e-44!GO:0044429;mitochondrial part;1.50809220202229e-43!GO:0015031;protein transport;1.51262776742757e-43!GO:0031967;organelle envelope;2.61314573444255e-41!GO:0044249;cellular biosynthetic process;2.85326659151914e-41!GO:0009058;biosynthetic process;3.36011911110157e-41!GO:0031975;envelope;4.45995284155678e-41!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;7.11115744975e-41!GO:0043228;non-membrane-bound organelle;1.75535217077964e-40!GO:0043232;intracellular non-membrane-bound organelle;1.75535217077964e-40!GO:0045184;establishment of protein localization;1.81138310304819e-40!GO:0010467;gene expression;5.49934147137588e-40!GO:0008104;protein localization;5.71270382646969e-40!GO:0033279;ribosomal subunit;7.83676729455085e-40!GO:0016071;mRNA metabolic process;9.08362245042766e-40!GO:0009059;macromolecule biosynthetic process;9.70153166155957e-40!GO:0008380;RNA splicing;4.59785093719285e-38!GO:0006996;organelle organization and biogenesis;1.32549609789034e-37!GO:0005829;cytosol;1.38890837989345e-37!GO:0046907;intracellular transport;6.03800757386309e-37!GO:0006259;DNA metabolic process;2.82727855481245e-35!GO:0006397;mRNA processing;3.22367370290051e-35!GO:0065003;macromolecular complex assembly;1.98233192794998e-34!GO:0022613;ribonucleoprotein complex biogenesis and assembly;3.00578278062086e-33!GO:0022607;cellular component assembly;2.59252714453673e-30!GO:0007049;cell cycle;1.79843580334089e-29!GO:0006886;intracellular protein transport;2.34462944116971e-29!GO:0005654;nucleoplasm;3.99951499826713e-29!GO:0005740;mitochondrial envelope;1.94553654901536e-27!GO:0005681;spliceosome;2.52289605222877e-27!GO:0005830;cytosolic ribosome (sensu Eukaryota);6.78858088596979e-27!GO:0019866;organelle inner membrane;4.56234065157437e-26!GO:0031966;mitochondrial membrane;4.66050810838505e-26!GO:0000166;nucleotide binding;7.91226680386017e-25!GO:0051649;establishment of cellular localization;3.00964233255958e-24!GO:0005743;mitochondrial inner membrane;5.51830847311221e-24!GO:0051641;cellular localization;8.30452628617766e-24!GO:0044451;nucleoplasm part;1.38885160292352e-23!GO:0022402;cell cycle process;1.1469599146493e-22!GO:0044445;cytosolic part;1.50958309055866e-22!GO:0000278;mitotic cell cycle;1.72542146437181e-22!GO:0003676;nucleic acid binding;2.69528776350281e-22!GO:0006119;oxidative phosphorylation;6.91559213697811e-22!GO:0016874;ligase activity;1.19573693562995e-21!GO:0016462;pyrophosphatase activity;1.39626677900184e-21!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.6611826804335e-21!GO:0016817;hydrolase activity, acting on acid anhydrides;2.58000826656501e-21!GO:0017111;nucleoside-triphosphatase activity;4.58238825427715e-21!GO:0015934;large ribosomal subunit;8.65236626274046e-21!GO:0006457;protein folding;1.57551493651177e-20!GO:0012505;endomembrane system;2.36841651824316e-20!GO:0006974;response to DNA damage stimulus;3.90128536427562e-20!GO:0015935;small ribosomal subunit;4.84522075348752e-20!GO:0005730;nucleolus;5.48867399504846e-20!GO:0044455;mitochondrial membrane part;1.13805012932279e-19!GO:0031980;mitochondrial lumen;2.05119268168291e-19!GO:0005759;mitochondrial matrix;2.05119268168291e-19!GO:0022618;protein-RNA complex assembly;4.46215540423407e-18!GO:0005694;chromosome;6.90821675452851e-18!GO:0032553;ribonucleotide binding;9.59375744914663e-18!GO:0032555;purine ribonucleotide binding;9.59375744914663e-18!GO:0000087;M phase of mitotic cell cycle;2.18954642599249e-17!GO:0005783;endoplasmic reticulum;2.19539622189953e-17!GO:0006281;DNA repair;2.19539622189953e-17!GO:0007067;mitosis;3.36987777330112e-17!GO:0017076;purine nucleotide binding;4.08549950858146e-17!GO:0022403;cell cycle phase;4.68129914864452e-17!GO:0008134;transcription factor binding;6.16153752791583e-17!GO:0016070;RNA metabolic process;1.10256422304366e-16!GO:0044427;chromosomal part;1.19673148105096e-16!GO:0006512;ubiquitin cycle;1.19914790441902e-16!GO:0006260;DNA replication;1.54701123470563e-16!GO:0000502;proteasome complex (sensu Eukaryota);1.54701123470563e-16!GO:0042254;ribosome biogenesis and assembly;3.88312095262458e-16!GO:0048770;pigment granule;4.05506537119668e-16!GO:0042470;melanosome;4.05506537119668e-16!GO:0005746;mitochondrial respiratory chain;4.79446662241127e-16!GO:0005761;mitochondrial ribosome;5.01704301868633e-16!GO:0000313;organellar ribosome;5.01704301868633e-16!GO:0051603;proteolysis involved in cellular protein catabolic process;5.92335568140255e-16!GO:0006511;ubiquitin-dependent protein catabolic process;8.84346896224994e-16!GO:0044432;endoplasmic reticulum part;8.85402800778687e-16!GO:0019941;modification-dependent protein catabolic process;9.25357490995618e-16!GO:0043632;modification-dependent macromolecule catabolic process;9.25357490995618e-16!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;9.37081715557466e-16!GO:0044265;cellular macromolecule catabolic process;1.10217892293159e-15!GO:0043285;biopolymer catabolic process;1.65727015705698e-15!GO:0044257;cellular protein catabolic process;1.82777804345727e-15!GO:0005524;ATP binding;2.70360854317345e-15!GO:0006605;protein targeting;3.5251476763903e-15!GO:0032559;adenyl ribonucleotide binding;5.96976717984733e-15!GO:0012501;programmed cell death;8.1989919827071e-15!GO:0008135;translation factor activity, nucleic acid binding;9.80761127754143e-15!GO:0050136;NADH dehydrogenase (quinone) activity;1.07578808121441e-14!GO:0003954;NADH dehydrogenase activity;1.07578808121441e-14!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.07578808121441e-14!GO:0006915;apoptosis;1.31829533219192e-14!GO:0005635;nuclear envelope;1.52490199290055e-14!GO:0051186;cofactor metabolic process;1.71820876326021e-14!GO:0051082;unfolded protein binding;1.9224805387049e-14!GO:0030554;adenyl nucleotide binding;3.37933722051114e-14!GO:0009719;response to endogenous stimulus;3.85703711067204e-14!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);5.66806419167686e-14!GO:0051276;chromosome organization and biogenesis;6.3535189211622e-14!GO:0000279;M phase;8.77426834012817e-14!GO:0030163;protein catabolic process;1.16228051581809e-13!GO:0051301;cell division;1.19225150915836e-13!GO:0009057;macromolecule catabolic process;1.46952874082337e-13!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.86063715807005e-13!GO:0005794;Golgi apparatus;2.00446419162915e-13!GO:0043412;biopolymer modification;2.36041136705904e-13!GO:0048193;Golgi vesicle transport;2.42211215408066e-13!GO:0031965;nuclear membrane;3.38460115234525e-13!GO:0008219;cell death;3.92266432692658e-13!GO:0016265;death;3.92266432692658e-13!GO:0044453;nuclear membrane part;4.93052189056941e-13!GO:0042775;organelle ATP synthesis coupled electron transport;6.77191871925293e-13!GO:0042773;ATP synthesis coupled electron transport;6.77191871925293e-13!GO:0000398;nuclear mRNA splicing, via spliceosome;8.24823736301842e-13!GO:0000375;RNA splicing, via transesterification reactions;8.24823736301842e-13!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;8.24823736301842e-13!GO:0030964;NADH dehydrogenase complex (quinone);8.67798641451621e-13!GO:0045271;respiratory chain complex I;8.67798641451621e-13!GO:0005747;mitochondrial respiratory chain complex I;8.67798641451621e-13!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.79068777500143e-12!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;2.28152199576362e-12!GO:0006913;nucleocytoplasmic transport;2.35645524308444e-12!GO:0016192;vesicle-mediated transport;2.36824190655777e-12!GO:0051726;regulation of cell cycle;3.80359373041134e-12!GO:0006399;tRNA metabolic process;4.78300445626199e-12!GO:0042175;nuclear envelope-endoplasmic reticulum network;4.82742318838216e-12!GO:0051169;nuclear transport;4.966266689696e-12!GO:0000074;regulation of progression through cell cycle;6.13782194473817e-12!GO:0006366;transcription from RNA polymerase II promoter;9.35716893143702e-12!GO:0044248;cellular catabolic process;9.81270155784573e-12!GO:0006732;coenzyme metabolic process;1.17622415754672e-11!GO:0006464;protein modification process;1.22467962484584e-11!GO:0016887;ATPase activity;1.26116163638155e-11!GO:0005789;endoplasmic reticulum membrane;1.40696635918652e-11!GO:0006413;translational initiation;1.85881932103321e-11!GO:0006446;regulation of translational initiation;2.03037728808002e-11!GO:0042623;ATPase activity, coupled;4.39900374239637e-11!GO:0016879;ligase activity, forming carbon-nitrogen bonds;4.42770924051405e-11!GO:0003743;translation initiation factor activity;4.93717767718206e-11!GO:0005643;nuclear pore;5.31315804349709e-11!GO:0050657;nucleic acid transport;5.90905553419911e-11!GO:0051236;establishment of RNA localization;5.90905553419911e-11!GO:0050658;RNA transport;5.90905553419911e-11!GO:0009259;ribonucleotide metabolic process;6.55248329800607e-11!GO:0006403;RNA localization;6.59363184710397e-11!GO:0008639;small protein conjugating enzyme activity;7.43837574113175e-11!GO:0006325;establishment and/or maintenance of chromatin architecture;1.04307298821775e-10!GO:0006364;rRNA processing;1.23636747468801e-10!GO:0016604;nuclear body;1.41542230617968e-10!GO:0065002;intracellular protein transport across a membrane;1.4960342168374e-10!GO:0004842;ubiquitin-protein ligase activity;2.12213866985128e-10!GO:0043687;post-translational protein modification;2.16356781610948e-10!GO:0006461;protein complex assembly;2.35994058147021e-10!GO:0016072;rRNA metabolic process;2.39078956624629e-10!GO:0003712;transcription cofactor activity;2.5866701786407e-10!GO:0048523;negative regulation of cellular process;3.37723775104782e-10!GO:0006323;DNA packaging;3.49536554078172e-10!GO:0006163;purine nucleotide metabolic process;4.17355273751062e-10!GO:0019787;small conjugating protein ligase activity;4.17966447219953e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;5.29645191779095e-10!GO:0009055;electron carrier activity;5.69926469319435e-10!GO:0004386;helicase activity;8.18711666705063e-10!GO:0009260;ribonucleotide biosynthetic process;9.25401029217347e-10!GO:0009150;purine ribonucleotide metabolic process;1.20021477884143e-09!GO:0042981;regulation of apoptosis;1.20021477884143e-09!GO:0065004;protein-DNA complex assembly;1.22918638644453e-09!GO:0043067;regulation of programmed cell death;1.46162777977961e-09!GO:0006164;purine nucleotide biosynthetic process;2.35277149029012e-09!GO:0000785;chromatin;2.89174764986552e-09!GO:0016881;acid-amino acid ligase activity;2.89174764986552e-09!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;3.68146617833527e-09!GO:0005793;ER-Golgi intermediate compartment;4.63658738556921e-09!GO:0017038;protein import;4.65980089977283e-09!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;4.74894250095438e-09!GO:0004812;aminoacyl-tRNA ligase activity;4.74894250095438e-09!GO:0016875;ligase activity, forming carbon-oxygen bonds;4.74894250095438e-09!GO:0009199;ribonucleoside triphosphate metabolic process;4.9236689870689e-09!GO:0046930;pore complex;4.96545893494368e-09!GO:0050794;regulation of cellular process;5.579346174528e-09!GO:0051028;mRNA transport;6.0684166171494e-09!GO:0009152;purine ribonucleotide biosynthetic process;6.54017000191098e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;7.03408924162221e-09!GO:0009141;nucleoside triphosphate metabolic process;7.71185488972574e-09!GO:0015630;microtubule cytoskeleton;8.7967662939024e-09!GO:0016607;nuclear speck;9.40582117047927e-09!GO:0043038;amino acid activation;1.04449997326473e-08!GO:0006418;tRNA aminoacylation for protein translation;1.04449997326473e-08!GO:0043039;tRNA aminoacylation;1.04449997326473e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.14892547900997e-08!GO:0009144;purine nucleoside triphosphate metabolic process;1.14892547900997e-08!GO:0008565;protein transporter activity;1.18754373962642e-08!GO:0007005;mitochondrion organization and biogenesis;1.21741405314365e-08!GO:0030532;small nuclear ribonucleoprotein complex;1.39005296250917e-08!GO:0048519;negative regulation of biological process;1.39295400688143e-08!GO:0008026;ATP-dependent helicase activity;1.42076050870459e-08!GO:0043566;structure-specific DNA binding;1.64405122239727e-08!GO:0009060;aerobic respiration;1.97286178957564e-08!GO:0006333;chromatin assembly or disassembly;2.39966009343504e-08!GO:0015986;ATP synthesis coupled proton transport;2.39966009343504e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;2.39966009343504e-08!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;2.73121031541034e-08!GO:0051246;regulation of protein metabolic process;2.73121031541034e-08!GO:0009142;nucleoside triphosphate biosynthetic process;2.95715107291647e-08!GO:0009201;ribonucleoside triphosphate biosynthetic process;2.95715107291647e-08!GO:0045333;cellular respiration;4.15433056987011e-08!GO:0043069;negative regulation of programmed cell death;4.32342207906993e-08!GO:0046034;ATP metabolic process;5.55652128786852e-08!GO:0051188;cofactor biosynthetic process;5.75682226910096e-08!GO:0003697;single-stranded DNA binding;5.76980990328379e-08!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;6.75399004760995e-08!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;7.17234241067344e-08!GO:0009145;purine nucleoside triphosphate biosynthetic process;7.17234241067344e-08!GO:0043066;negative regulation of apoptosis;7.17234241067344e-08!GO:0006916;anti-apoptosis;7.35782598333948e-08!GO:0032446;protein modification by small protein conjugation;1.0284151301655e-07!GO:0006888;ER to Golgi vesicle-mediated transport;1.09093277481326e-07!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;1.21558770683519e-07!GO:0016779;nucleotidyltransferase activity;1.57196675337918e-07!GO:0005768;endosome;1.66680262196016e-07!GO:0005839;proteasome core complex (sensu Eukaryota);1.69307016472398e-07!GO:0019829;cation-transporting ATPase activity;1.73881567434569e-07!GO:0006261;DNA-dependent DNA replication;1.77710625811047e-07!GO:0016567;protein ubiquitination;1.79673493927229e-07!GO:0005667;transcription factor complex;1.84568708117244e-07!GO:0003924;GTPase activity;2.81146076858738e-07!GO:0006754;ATP biosynthetic process;3.00162308970477e-07!GO:0006753;nucleoside phosphate metabolic process;3.00162308970477e-07!GO:0007249;I-kappaB kinase/NF-kappaB cascade;3.60679946617239e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;3.84806543310454e-07!GO:0043623;cellular protein complex assembly;3.96201078232039e-07!GO:0009056;catabolic process;3.96201078232039e-07!GO:0016469;proton-transporting two-sector ATPase complex;4.78409195418362e-07!GO:0009117;nucleotide metabolic process;6.46990235020013e-07!GO:0030120;vesicle coat;9.27297957127091e-07!GO:0030662;coated vesicle membrane;9.27297957127091e-07!GO:0005819;spindle;9.9427703731789e-07!GO:0031324;negative regulation of cellular metabolic process;1.02555845177556e-06!GO:0009108;coenzyme biosynthetic process;1.05266334430164e-06!GO:0004298;threonine endopeptidase activity;1.07631925393808e-06!GO:0048522;positive regulation of cellular process;1.3929267515414e-06!GO:0006334;nucleosome assembly;1.39929857347684e-06!GO:0006099;tricarboxylic acid cycle;1.47974236812442e-06!GO:0046356;acetyl-CoA catabolic process;1.47974236812442e-06!GO:0016568;chromatin modification;1.57017727780112e-06!GO:0015078;hydrogen ion transmembrane transporter activity;1.70360883499992e-06!GO:0006357;regulation of transcription from RNA polymerase II promoter;1.83100724008659e-06!GO:0051329;interphase of mitotic cell cycle;1.87818331521966e-06!GO:0031252;leading edge;1.95206047452777e-06!GO:0051325;interphase;2.19941075018606e-06!GO:0045259;proton-transporting ATP synthase complex;2.2187349660369e-06!GO:0005813;centrosome;2.38536879024756e-06!GO:0006084;acetyl-CoA metabolic process;2.45534287693329e-06!GO:0006793;phosphorus metabolic process;2.73316473768602e-06!GO:0006796;phosphate metabolic process;2.73316473768602e-06!GO:0000245;spliceosome assembly;2.785468751991e-06!GO:0006752;group transfer coenzyme metabolic process;2.91116180585872e-06!GO:0000775;chromosome, pericentric region;2.95925580794447e-06!GO:0005657;replication fork;3.16909860421115e-06!GO:0016787;hydrolase activity;3.31005418314299e-06!GO:0031497;chromatin assembly;3.88173970915133e-06!GO:0005762;mitochondrial large ribosomal subunit;5.01670481668805e-06!GO:0000315;organellar large ribosomal subunit;5.01670481668805e-06!GO:0051168;nuclear export;5.11718239319791e-06!GO:0051170;nuclear import;5.19466976199823e-06!GO:0005815;microtubule organizing center;5.74190983371491e-06!GO:0005788;endoplasmic reticulum lumen;5.84112577250381e-06!GO:0019899;enzyme binding;6.25768932097339e-06!GO:0016563;transcription activator activity;6.3167178643578e-06!GO:0050789;regulation of biological process;6.32393320498225e-06!GO:0048475;coated membrane;6.77561655755086e-06!GO:0030117;membrane coat;6.77561655755086e-06!GO:0016564;transcription repressor activity;7.05890404773719e-06!GO:0007051;spindle organization and biogenesis;8.03674726448798e-06!GO:0006606;protein import into nucleus;8.75795688909847e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;8.87461618849347e-06!GO:0005773;vacuole;9.08116948233965e-06!GO:0044431;Golgi apparatus part;9.98513517465808e-06!GO:0000075;cell cycle checkpoint;1.09598709433347e-05!GO:0000151;ubiquitin ligase complex;1.12077546315857e-05!GO:0016740;transferase activity;1.27261047687775e-05!GO:0009892;negative regulation of metabolic process;1.37740639436483e-05!GO:0006613;cotranslational protein targeting to membrane;1.52123110333501e-05!GO:0007243;protein kinase cascade;1.52123110333501e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;1.53593929434237e-05!GO:0009109;coenzyme catabolic process;1.62939726285464e-05!GO:0016853;isomerase activity;1.62980652599976e-05!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.66535355225737e-05!GO:0008654;phospholipid biosynthetic process;1.68146201561617e-05!GO:0003899;DNA-directed RNA polymerase activity;1.72796485865439e-05!GO:0016310;phosphorylation;1.80646663479948e-05!GO:0000314;organellar small ribosomal subunit;2.01325998781105e-05!GO:0005763;mitochondrial small ribosomal subunit;2.01325998781105e-05!GO:0003714;transcription corepressor activity;2.10765186499181e-05!GO:0003713;transcription coactivator activity;2.11323703281232e-05!GO:0007010;cytoskeleton organization and biogenesis;2.20466565989076e-05!GO:0051427;hormone receptor binding;2.94528492866625e-05!GO:0045786;negative regulation of progression through cell cycle;3.9458997652861e-05!GO:0051187;cofactor catabolic process;4.06831625780037e-05!GO:0005525;GTP binding;4.16779174643515e-05!GO:0003724;RNA helicase activity;5.17911218699733e-05!GO:0005770;late endosome;5.50242594337279e-05!GO:0007088;regulation of mitosis;5.7501847722213e-05!GO:0043021;ribonucleoprotein binding;5.83117536159758e-05!GO:0000323;lytic vacuole;5.85767458635374e-05!GO:0005764;lysosome;5.85767458635374e-05!GO:0016363;nuclear matrix;6.25333148674104e-05!GO:0035257;nuclear hormone receptor binding;6.53009760345936e-05!GO:0003690;double-stranded DNA binding;6.76511281332536e-05!GO:0008361;regulation of cell size;6.78168403012792e-05!GO:0006626;protein targeting to mitochondrion;7.15382311033485e-05!GO:0043681;protein import into mitochondrion;8.17117521776088e-05!GO:0030867;rough endoplasmic reticulum membrane;8.43977800098349e-05!GO:0030036;actin cytoskeleton organization and biogenesis;8.46798283308114e-05!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;8.94323591193741e-05!GO:0008033;tRNA processing;9.00200055577365e-05!GO:0008094;DNA-dependent ATPase activity;9.0854789765454e-05!GO:0031988;membrane-bound vesicle;9.79408989730226e-05!GO:0016049;cell growth;0.000101564011808571!GO:0016859;cis-trans isomerase activity;0.000102402656165461!GO:0003729;mRNA binding;0.000106921435220753!GO:0045454;cell redox homeostasis;0.000110883504736075!GO:0051052;regulation of DNA metabolic process;0.000118636966828754!GO:0016023;cytoplasmic membrane-bound vesicle;0.000122349033692509!GO:0044440;endosomal part;0.000124952570967297!GO:0010008;endosome membrane;0.000124952570967297!GO:0015077;monovalent inorganic cation transmembrane transporter activity;0.000129313263992926!GO:0001558;regulation of cell growth;0.000133583036657445!GO:0051789;response to protein stimulus;0.000170854326611094!GO:0006986;response to unfolded protein;0.000170854326611094!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00017799758192878!GO:0005798;Golgi-associated vesicle;0.000182701780302678!GO:0006302;double-strand break repair;0.000199514817140097!GO:0006839;mitochondrial transport;0.000199514817140097!GO:0042802;identical protein binding;0.000204994421278728!GO:0016481;negative regulation of transcription;0.000207960004155262!GO:0005769;early endosome;0.000207960004155262!GO:0048518;positive regulation of biological process;0.000209082225971029!GO:0033116;ER-Golgi intermediate compartment membrane;0.000273131892345447!GO:0003682;chromatin binding;0.000286277963009511!GO:0000139;Golgi membrane;0.00029222859080373!GO:0065009;regulation of a molecular function;0.000293023345444723!GO:0005905;coated pit;0.000293023345444723!GO:0032561;guanyl ribonucleotide binding;0.00035194624790522!GO:0019001;guanyl nucleotide binding;0.00035194624790522!GO:0031982;vesicle;0.000369995726619015!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000386560088380462!GO:0001726;ruffle;0.000389044430413704!GO:0003684;damaged DNA binding;0.00041311107751724!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00043266690969045!GO:0051252;regulation of RNA metabolic process;0.000443510161099668!GO:0004576;oligosaccharyl transferase activity;0.000466871555217084!GO:0008250;oligosaccharyl transferase complex;0.000494269650719255!GO:0006612;protein targeting to membrane;0.000498164540330977!GO:0005048;signal sequence binding;0.000536380298426354!GO:0030029;actin filament-based process;0.000538352848610737!GO:0019222;regulation of metabolic process;0.000557323407213058!GO:0015980;energy derivation by oxidation of organic compounds;0.000560713072610637!GO:0009165;nucleotide biosynthetic process;0.000571255736699328!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000574320039910404!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000580899324153069!GO:0006383;transcription from RNA polymerase III promoter;0.000607448545275261!GO:0048471;perinuclear region of cytoplasm;0.000622951715574284!GO:0031410;cytoplasmic vesicle;0.000636417593039043!GO:0044452;nucleolar part;0.000695244501251864!GO:0030880;RNA polymerase complex;0.00071624386435792!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000734545514338512!GO:0006405;RNA export from nucleus;0.000763916017729664!GO:0016044;membrane organization and biogenesis;0.000833278173829628!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000850115140059246!GO:0006352;transcription initiation;0.000858417468304241!GO:0000776;kinetochore;0.000898833999004707!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000900392563710747!GO:0007059;chromosome segregation;0.000900392563710747!GO:0006402;mRNA catabolic process;0.000902543175368734!GO:0006414;translational elongation;0.000914891566580845!GO:0051920;peroxiredoxin activity;0.000935851979676089!GO:0046489;phosphoinositide biosynthetic process;0.000958664485575106!GO:0048468;cell development;0.000960548596309436!GO:0046474;glycerophospholipid biosynthetic process;0.000970971586094612!GO:0031968;organelle outer membrane;0.00102095139961234!GO:0048487;beta-tubulin binding;0.00107795546081067!GO:0005852;eukaryotic translation initiation factor 3 complex;0.0010806945634824!GO:0040008;regulation of growth;0.00110181086179296!GO:0019867;outer membrane;0.00113711781766068!GO:0003746;translation elongation factor activity;0.00117349144308302!GO:0006091;generation of precursor metabolites and energy;0.00121115033315746!GO:0033673;negative regulation of kinase activity;0.00123034731888554!GO:0006469;negative regulation of protein kinase activity;0.00123034731888554!GO:0006310;DNA recombination;0.00125360367786672!GO:0046983;protein dimerization activity;0.00128037477618502!GO:0007006;mitochondrial membrane organization and biogenesis;0.00128738843533185!GO:0008186;RNA-dependent ATPase activity;0.00129429509158188!GO:0005885;Arp2/3 protein complex;0.00134571992463092!GO:0006950;response to stress;0.0013829116823283!GO:0005874;microtubule;0.00138438098484854!GO:0000049;tRNA binding;0.00141301454113291!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00142253028240165!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00142253028240165!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00142253028240165!GO:0045941;positive regulation of transcription;0.00144749875508513!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00149941045909977!GO:0016272;prefoldin complex;0.00155631100790801!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00158529462783936!GO:0000428;DNA-directed RNA polymerase complex;0.00158529462783936!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00158529462783936!GO:0016197;endosome transport;0.00160133598787887!GO:0046467;membrane lipid biosynthetic process;0.00161679800316776!GO:0043596;nuclear replication fork;0.00163314631915481!GO:0019843;rRNA binding;0.00168139077245998!GO:0003711;transcription elongation regulator activity;0.00178355870638387!GO:0032508;DNA duplex unwinding;0.00180401540511376!GO:0032392;DNA geometric change;0.00180401540511376!GO:0009967;positive regulation of signal transduction;0.00184032053662107!GO:0006401;RNA catabolic process;0.00184032053662107!GO:0003678;DNA helicase activity;0.00184032053662107!GO:0045893;positive regulation of transcription, DNA-dependent;0.00193429522580709!GO:0000059;protein import into nucleus, docking;0.00194625702431226!GO:0007093;mitotic cell cycle checkpoint;0.00199059352690488!GO:0004527;exonuclease activity;0.00200458568712517!GO:0051348;negative regulation of transferase activity;0.00208623444860919!GO:0048500;signal recognition particle;0.0021099517773246!GO:0018196;peptidyl-asparagine modification;0.00234044433992921!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00234044433992921!GO:0000082;G1/S transition of mitotic cell cycle;0.00236400612583245!GO:0000786;nucleosome;0.00238493847583865!GO:0005741;mitochondrial outer membrane;0.00243206060436818!GO:0006268;DNA unwinding during replication;0.00243457121878699!GO:0005684;U2-dependent spliceosome;0.00243574110682005!GO:0007052;mitotic spindle organization and biogenesis;0.00261968366779063!GO:0016126;sterol biosynthetic process;0.00265960456289687!GO:0008022;protein C-terminus binding;0.00275034952342515!GO:0006891;intra-Golgi vesicle-mediated transport;0.00280372030504856!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.00293178487625556!GO:0015399;primary active transmembrane transporter activity;0.00293178487625556!GO:0008312;7S RNA binding;0.00301702773035052!GO:0008092;cytoskeletal protein binding;0.00316236010626263!GO:0006818;hydrogen transport;0.00322169482421975!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00330315913646886!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00330315913646886!GO:0008243;plasminogen activator activity;0.00336182063943934!GO:0005791;rough endoplasmic reticulum;0.00337272917329252!GO:0004004;ATP-dependent RNA helicase activity;0.00338182834702613!GO:0030027;lamellipodium;0.00348670445626587!GO:0016491;oxidoreductase activity;0.00348670445626587!GO:0030132;clathrin coat of coated pit;0.0035201389883449!GO:0015992;proton transport;0.00353524767004514!GO:0065007;biological regulation;0.00354329169226933!GO:0006520;amino acid metabolic process;0.00355207847660029!GO:0016251;general RNA polymerase II transcription factor activity;0.00365196195930963!GO:0043065;positive regulation of apoptosis;0.0036979570379464!GO:0030521;androgen receptor signaling pathway;0.00371194198235299!GO:0015631;tubulin binding;0.00378544168285119!GO:0006275;regulation of DNA replication;0.00386960821956425!GO:0043488;regulation of mRNA stability;0.00394892929627293!GO:0043487;regulation of RNA stability;0.00394892929627293!GO:0030176;integral to endoplasmic reticulum membrane;0.00398728515510112!GO:0051087;chaperone binding;0.00410001783684636!GO:0009112;nucleobase metabolic process;0.00415074524595514!GO:0008632;apoptotic program;0.00415074524595514!GO:0030663;COPI coated vesicle membrane;0.00415118860549372!GO:0030126;COPI vesicle coat;0.00415118860549372!GO:0031072;heat shock protein binding;0.00431313493400122!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00451011308170803!GO:0005637;nuclear inner membrane;0.00466377932937453!GO:0009116;nucleoside metabolic process;0.00482883350172266!GO:0006611;protein export from nucleus;0.00487849419788988!GO:0006497;protein amino acid lipidation;0.00499249162986271!GO:0030865;cortical cytoskeleton organization and biogenesis;0.00509517902924219!GO:0043068;positive regulation of programmed cell death;0.00512243581726021!GO:0051338;regulation of transferase activity;0.00547033951966357!GO:0006417;regulation of translation;0.00566245156919529!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00595171942434456!GO:0045047;protein targeting to ER;0.00595171942434456!GO:0043284;biopolymer biosynthetic process;0.00602356143258127!GO:0043022;ribosome binding;0.00612429257233922!GO:0035258;steroid hormone receptor binding;0.00637270229943731!GO:0006289;nucleotide-excision repair;0.00643262550972458!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00656684651228254!GO:0008408;3'-5' exonuclease activity;0.00680513722619471!GO:0050790;regulation of catalytic activity;0.00695042073397967!GO:0006984;ER-nuclear signaling pathway;0.00720763214442968!GO:0043549;regulation of kinase activity;0.00720763214442968!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00736444343642838!GO:0008139;nuclear localization sequence binding;0.00744727475278075!GO:0043601;nuclear replisome;0.00752002272723526!GO:0030894;replisome;0.00752002272723526!GO:0051059;NF-kappaB binding;0.00758717901815161!GO:0030658;transport vesicle membrane;0.00761782178958562!GO:0030137;COPI-coated vesicle;0.00775570235393841!GO:0017166;vinculin binding;0.00788647791398537!GO:0006144;purine base metabolic process;0.00799906758138627!GO:0006506;GPI anchor biosynthetic process;0.00814515888377442!GO:0006270;DNA replication initiation;0.00824771984601816!GO:0032200;telomere organization and biogenesis;0.00834268031658058!GO:0000723;telomere maintenance;0.00834268031658058!GO:0006595;polyamine metabolic process;0.00849400306273557!GO:0051540;metal cluster binding;0.00850642920334683!GO:0051536;iron-sulfur cluster binding;0.00850642920334683!GO:0008180;signalosome;0.00864577260452475!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00894278860298938!GO:0007021;tubulin folding;0.00903334613965311!GO:0044262;cellular carbohydrate metabolic process;0.00917252470456092!GO:0016407;acetyltransferase activity;0.00927630247916947!GO:0042770;DNA damage response, signal transduction;0.00930958803002809!GO:0030384;phosphoinositide metabolic process;0.00946876901121918!GO:0009889;regulation of biosynthetic process;0.00954598923773524!GO:0006695;cholesterol biosynthetic process;0.00994162760841793!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.0100363792928878!GO:0006509;membrane protein ectodomain proteolysis;0.0100363792928878!GO:0033619;membrane protein proteolysis;0.0100363792928878!GO:0031124;mRNA 3'-end processing;0.0100946362582576!GO:0046483;heterocycle metabolic process;0.0101337114351756!GO:0006354;RNA elongation;0.0102026398237341!GO:0030133;transport vesicle;0.0105036212588264!GO:0006284;base-excision repair;0.0107600194636159!GO:0019752;carboxylic acid metabolic process;0.0109699748772604!GO:0030118;clathrin coat;0.0109699748772604!GO:0007017;microtubule-based process;0.0109985600454856!GO:0006650;glycerophospholipid metabolic process;0.0111186876110686!GO:0006376;mRNA splice site selection;0.0111230697293437!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0111230697293437!GO:0000178;exosome (RNase complex);0.0111678650465877!GO:0008283;cell proliferation;0.0113570260257699!GO:0006505;GPI anchor metabolic process;0.011718354733721!GO:0004674;protein serine/threonine kinase activity;0.0118511116612589!GO:0045045;secretory pathway;0.0119959890044769!GO:0047485;protein N-terminus binding;0.0123604170518414!GO:0005832;chaperonin-containing T-complex;0.0126486195614473!GO:0006082;organic acid metabolic process;0.0127726651224458!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0131717255611247!GO:0050681;androgen receptor binding;0.0134345773128005!GO:0003702;RNA polymerase II transcription factor activity;0.0134438529371206!GO:0046966;thyroid hormone receptor binding;0.0135387641588556!GO:0045859;regulation of protein kinase activity;0.0137028870372164!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0138513846299162!GO:0030660;Golgi-associated vesicle membrane;0.0144960586685815!GO:0008652;amino acid biosynthetic process;0.014706796720126!GO:0019206;nucleoside kinase activity;0.0150038082428522!GO:0009893;positive regulation of metabolic process;0.0150337402569372!GO:0042158;lipoprotein biosynthetic process;0.0151398714873612!GO:0008168;methyltransferase activity;0.0151398714873612!GO:0046982;protein heterodimerization activity;0.0151398714873612!GO:0000209;protein polyubiquitination;0.0151768204400744!GO:0030134;ER to Golgi transport vesicle;0.0152024629799593!GO:0051539;4 iron, 4 sulfur cluster binding;0.0153675172962177!GO:0008637;apoptotic mitochondrial changes;0.0157768669011161!GO:0006338;chromatin remodeling;0.0157954372651454!GO:0050811;GABA receptor binding;0.0158615334087945!GO:0016741;transferase activity, transferring one-carbon groups;0.016075932665095!GO:0000339;RNA cap binding;0.0161259045563239!GO:0031326;regulation of cellular biosynthetic process;0.0162841752218178!GO:0030866;cortical actin cytoskeleton organization and biogenesis;0.0163142798212465!GO:0004532;exoribonuclease activity;0.0163626380242649!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0163626380242649!GO:0030125;clathrin vesicle coat;0.0169165824551993!GO:0030665;clathrin coated vesicle membrane;0.0169165824551993!GO:0045892;negative regulation of transcription, DNA-dependent;0.0170857914458905!GO:0042393;histone binding;0.0170864980910772!GO:0006672;ceramide metabolic process;0.0171739014936575!GO:0007050;cell cycle arrest;0.0175161937541001!GO:0031529;ruffle organization and biogenesis;0.0178174018187423!GO:0005869;dynactin complex;0.0178888948767923!GO:0000096;sulfur amino acid metabolic process;0.0180408084520252!GO:0005774;vacuolar membrane;0.0180533853732732!GO:0045792;negative regulation of cell size;0.0184950202663509!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0186904986365187!GO:0030031;cell projection biogenesis;0.0188618656444017!GO:0000781;chromosome, telomeric region;0.0189332978293326!GO:0016584;nucleosome positioning;0.0189332978293326!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.019086828090528!GO:0008610;lipid biosynthetic process;0.0192209848757631!GO:0005758;mitochondrial intermembrane space;0.019283685471291!GO:0030433;ER-associated protein catabolic process;0.0199510628097845!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0199510628097845!GO:0005876;spindle microtubule;0.0200242440577366!GO:0008047;enzyme activator activity;0.0206330580814257!GO:0043130;ubiquitin binding;0.0206330580814257!GO:0032182;small conjugating protein binding;0.0206330580814257!GO:0000922;spindle pole;0.0212575369766776!GO:0006406;mRNA export from nucleus;0.0217165702960373!GO:0008538;proteasome activator activity;0.0217522637195149!GO:0007264;small GTPase mediated signal transduction;0.0219256175307989!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0219256175307989!GO:0045039;protein import into mitochondrial inner membrane;0.0219256175307989!GO:0016408;C-acyltransferase activity;0.0225329040216447!GO:0030308;negative regulation of cell growth;0.0226441481039767!GO:0007034;vacuolar transport;0.0227052145869857!GO:0006378;mRNA polyadenylation;0.0232645568876357!GO:0004518;nuclease activity;0.0234638117331222!GO:0043492;ATPase activity, coupled to movement of substances;0.0237688726433647!GO:0043624;cellular protein complex disassembly;0.0239313872061227!GO:0008629;induction of apoptosis by intracellular signals;0.0239415302290538!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0239415302290538!GO:0031323;regulation of cellular metabolic process;0.0240038097187677!GO:0030518;steroid hormone receptor signaling pathway;0.0244535507544261!GO:0031970;organelle envelope lumen;0.0246564263042301!GO:0006220;pyrimidine nucleotide metabolic process;0.0247580956040325!GO:0022415;viral reproductive process;0.0247580956040325!GO:0030127;COPII vesicle coat;0.0248349354438858!GO:0012507;ER to Golgi transport vesicle membrane;0.0248349354438858!GO:0006892;post-Golgi vesicle-mediated transport;0.0249279051736897!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0251797347939569!GO:0015002;heme-copper terminal oxidase activity;0.0251797347939569!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0251797347939569!GO:0004129;cytochrome-c oxidase activity;0.0251797347939569!GO:0043407;negative regulation of MAP kinase activity;0.0251873410708528!GO:0000228;nuclear chromosome;0.0251873410708528!GO:0032984;macromolecular complex disassembly;0.0256338522586991!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.0264453928723371!GO:0031123;RNA 3'-end processing;0.0265728284170471!GO:0043189;H4/H2A histone acetyltransferase complex;0.026848468794555!GO:0045926;negative regulation of growth;0.0269849362235056!GO:0022890;inorganic cation transmembrane transporter activity;0.0269849362235056!GO:0005669;transcription factor TFIID complex;0.0270196414731528!GO:0046519;sphingoid metabolic process;0.0270636250942823!GO:0043086;negative regulation of catalytic activity;0.0272463305677623!GO:0008234;cysteine-type peptidase activity;0.0278286027904937!GO:0009303;rRNA transcription;0.0284699633160673!GO:0003923;GPI-anchor transamidase activity;0.0285921564777858!GO:0016255;attachment of GPI anchor to protein;0.0285921564777858!GO:0042765;GPI-anchor transamidase complex;0.0285921564777858!GO:0031625;ubiquitin protein ligase binding;0.0291524394850694!GO:0006360;transcription from RNA polymerase I promoter;0.029260359011282!GO:0007004;telomere maintenance via telomerase;0.029644213930604!GO:0030659;cytoplasmic vesicle membrane;0.029644213930604!GO:0007040;lysosome organization and biogenesis;0.0296550973669741!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0296932278345973!GO:0032906;transforming growth factor-beta2 production;0.0298089703402505!GO:0032909;regulation of transforming growth factor-beta2 production;0.0298089703402505!GO:0006643;membrane lipid metabolic process;0.02997915105574!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0300265470951143!GO:0009451;RNA modification;0.0303241382560685!GO:0007346;regulation of progression through mitotic cell cycle;0.0303997858035077!GO:0009124;nucleoside monophosphate biosynthetic process;0.0313754231916585!GO:0009123;nucleoside monophosphate metabolic process;0.0313754231916585!GO:0031901;early endosome membrane;0.0321351447903187!GO:0006458;'de novo' protein folding;0.0322454892440563!GO:0051084;'de novo' posttranslational protein folding;0.0322454892440563!GO:0005096;GTPase activator activity;0.0323245402538925!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.0326124453893497!GO:0007041;lysosomal transport;0.0327253600729187!GO:0048146;positive regulation of fibroblast proliferation;0.0332106281035152!GO:0030119;AP-type membrane coat adaptor complex;0.0333409871512629!GO:0046822;regulation of nucleocytoplasmic transport;0.0333507039502627!GO:0031570;DNA integrity checkpoint;0.0336130771420128!GO:0006740;NADPH regeneration;0.0338525915601286!GO:0006098;pentose-phosphate shunt;0.0338525915601286!GO:0000819;sister chromatid segregation;0.0338525915601286!GO:0001836;release of cytochrome c from mitochondria;0.0342192598344329!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.034404873626008!GO:0004860;protein kinase inhibitor activity;0.0349518556268932!GO:0048144;fibroblast proliferation;0.0350076423087467!GO:0048145;regulation of fibroblast proliferation;0.0350076423087467!GO:0032259;methylation;0.0350279878478359!GO:0031902;late endosome membrane;0.0351080756384621!GO:0006897;endocytosis;0.035337419591441!GO:0010324;membrane invagination;0.035337419591441!GO:0043241;protein complex disassembly;0.0356163670318896!GO:0017134;fibroblast growth factor binding;0.0361803075238514!GO:0000118;histone deacetylase complex;0.0373625192498766!GO:0000070;mitotic sister chromatid segregation;0.0374327680316335!GO:0044437;vacuolar part;0.0380936555429108!GO:0004003;ATP-dependent DNA helicase activity;0.0387891983997673!GO:0044433;cytoplasmic vesicle part;0.0393513811921735!GO:0005784;translocon complex;0.0396076302040437!GO:0006607;NLS-bearing substrate import into nucleus;0.0399326965315319!GO:0006400;tRNA modification;0.0405866605345919!GO:0008320;protein transmembrane transporter activity;0.0410945722972242!GO:0031371;ubiquitin conjugating enzyme complex;0.0411579381141091!GO:0051098;regulation of binding;0.041468530687269!GO:0030041;actin filament polymerization;0.0415368242734951!GO:0000792;heterochromatin;0.0417684320371381!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0419973757859949!GO:0010257;NADH dehydrogenase complex assembly;0.0419973757859949!GO:0033108;mitochondrial respiratory chain complex assembly;0.0419973757859949!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0424961881751073!GO:0035035;histone acetyltransferase binding;0.0426881495425704!GO:0022884;macromolecule transmembrane transporter activity;0.0428891692096706!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0428891692096706!GO:0005092;GDP-dissociation inhibitor activity;0.0430505802340055!GO:0006519;amino acid and derivative metabolic process;0.0430713425170378!GO:0008097;5S rRNA binding;0.0440030346198481!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0445077417764856!GO:0046128;purine ribonucleoside metabolic process;0.0447063856705616!GO:0042278;purine nucleoside metabolic process;0.0447063856705616!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0451493020256801!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0455625568807295!GO:0016311;dephosphorylation;0.0455829211906338!GO:0006807;nitrogen compound metabolic process;0.0456953837732544!GO:0043154;negative regulation of caspase activity;0.0460896363509419!GO:0007030;Golgi organization and biogenesis;0.0462457408084293!GO:0043414;biopolymer methylation;0.0462520131030702!GO:0030833;regulation of actin filament polymerization;0.0470085434090745!GO:0035267;NuA4 histone acetyltransferase complex;0.0480928021422535!GO:0005765;lysosomal membrane;0.0494701414581538!GO:0051128;regulation of cellular component organization and biogenesis;0.0497645446870722 | |||
|sample_id=10437 | |sample_id=10437 | ||
|sample_note= | |sample_note= | ||
| Line 76: | Line 99: | ||
|sample_tissue=thyroid | |sample_tissue=thyroid | ||
|top_motifs=ZBTB16:1.9410127768;UFEwm:1.42020842842;bHLH_family:1.36608134594;ALX4:1.16637654678;AIRE:1.00542013034;E2F1..5:1.0036815997;FOXQ1:1.00161659966;BPTF:0.962569422217;FOX{I1,J2}:0.954549016019;NFE2L1:0.94899217403;NKX2-1,4:0.907491277775;HES1:0.887493815978;PITX1..3:0.882767553229;PAX6:0.841438714759;ARID5B:0.834997262615;GATA4:0.818723207432;TEAD1:0.799566868263;TFDP1:0.794229063103;ONECUT1,2:0.726388951326;NKX3-1:0.711223002687;CDX1,2,4:0.692131338317;ELK1,4_GABP{A,B1}:0.663165505419;EVI1:0.6597704156;GZF1:0.618394808004;POU2F1..3:0.601796625797;HMGA1,2:0.600732421524;NKX2-2,8:0.589875282286;MYB:0.569870208251;MYOD1:0.550018512124;PAX8:0.540905320469;ZIC1..3:0.533111513046;PAX4:0.521182814049;ZBTB6:0.519128813536;HIF1A:0.514807095924;EP300:0.500490075411;TLX1..3_NFIC{dimer}:0.458122991684;PRDM1:0.456878442751;CDC5L:0.435117097544;GCM1,2:0.398031930797;HOX{A5,B5}:0.397224782708;FOXM1:0.390575136777;HMX1:0.384042158077;IKZF1:0.371243862457;ZNF384:0.357313508644;FOXP1:0.323212458363;TBX4,5:0.298725066801;FOXD3:0.276680380656;NRF1:0.264653097238;TEF:0.251859387135;NFY{A,B,C}:0.233894955411;FOS_FOS{B,L1}_JUN{B,D}:0.228417120828;YY1:0.224533481944;FOX{D1,D2}:0.219524492618;IRF7:0.20541034471;ZEB1:0.199092483485;PPARG:0.18637112272;TOPORS:0.181023777928;BACH2:0.177670742176;KLF4:0.171444931506;ZNF143:0.165437990489;HSF1,2:0.164326546625;SNAI1..3:0.159972050062;NR6A1:0.156990554257;RXR{A,B,G}:0.154584954641;POU3F1..4:0.152738098329;IRF1,2:0.143973265482;HOXA9_MEIS1:0.135432147472;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.130254600402;ALX1:0.129110296976;TBP:0.116941469408;STAT2,4,6:0.109650918609;GTF2A1,2:0.0985271741668;CEBPA,B_DDIT3:0.0974352634715;HOX{A4,D4}:0.095155943444;FOXL1:0.0939191847631;HLF:0.0811589302952;FOXO1,3,4:0.0691392346063;RFX1:0.0528013319559;EN1,2:-0.000427602751116;POU1F1:-0.00319552301663;PAX5:-0.0151409299124;RXRA_VDR{dimer}:-0.0196443145096;VSX1,2:-0.0262523799572;NFATC1..3:-0.0591485214254;LHX3,4:-0.0621625634897;IKZF2:-0.0630903444712;REST:-0.0684297916592;GFI1:-0.0744203744778;RBPJ:-0.0788864450169;TP53:-0.084946786714;LEF1_TCF7_TCF7L1,2:-0.11509564432;T:-0.117432042703;ATF4:-0.126278894066;POU5F1:-0.131105106744;NR3C1:-0.156184129237;XCPE1{core}:-0.159694057542;LMO2:-0.172428363161;TAL1_TCF{3,4,12}:-0.178434489979;BREu{core}:-0.178837431279;STAT5{A,B}:-0.185348275677;ELF1,2,4:-0.189981017306;FOXA2:-0.192109979197;HNF1A:-0.192609142867;ESRRA:-0.19727517054;NKX3-2:-0.199705900911;MYBL2:-0.199929796193;NFKB1_REL_RELA:-0.202697328511;NKX6-1,2:-0.207673937638;ATF5_CREB3:-0.211743590953;SP1:-0.218407139932;POU6F1:-0.235009474657;PDX1:-0.235224799196;HNF4A_NR2F1,2:-0.23646552254;SPIB:-0.258725383555;FOSL2:-0.259294510815;TFAP2B:-0.265428906463;NFE2:-0.271017499331;ZNF423:-0.271555779324;ZFP161:-0.280269796986;AHR_ARNT_ARNT2:-0.2924388907;ZNF148:-0.302465362314;SOX17:-0.306639660599;SOX{8,9,10}:-0.307440882047;SREBF1,2:-0.328720891957;GTF2I:-0.346099540064;NFIX:-0.351216599129;PBX1:-0.352663481808;MTE{core}:-0.356701143818;NR1H4:-0.359808164535;NHLH1,2:-0.366716292511;FOXP3:-0.368022086575;OCT4_SOX2{dimer}:-0.368937101326;ETS1,2:-0.37672733219;RREB1:-0.379458480536;MED-1{core}:-0.39061685089;CUX2:-0.397157604269;HIC1:-0.405183473467;SRF:-0.414391887663;SPI1:-0.421647947338;TFCP2:-0.449647598625;CREB1:-0.452925063023;SPZ1:-0.461511107028;NFE2L2:-0.4669215172;MYFfamily:-0.480590823942;DMAP1_NCOR{1,2}_SMARC:-0.487594509605;XBP1:-0.49053193917;GLI1..3:-0.510124748078;MEF2{A,B,C,D}:-0.526641615525;HBP1_HMGB_SSRP1_UBTF:-0.527514231803;GFI1B:-0.546216378479;MZF1:-0.571690020615;JUN:-0.586215069249;PRRX1,2:-0.595899091418;PAX2:-0.613222108791;MTF1:-0.635313653537;RFX2..5_RFXANK_RFXAP:-0.649149607995;FOXN1:-0.653553822232;PATZ1:-0.659628715676;FOX{F1,F2,J1}:-0.660700345338;MAZ:-0.671070725819;PAX1,9:-0.673320661506;SOX2:-0.693961179965;TFAP2{A,C}:-0.694838794108;SOX5:-0.730300967305;GATA6:-0.731872080972;ADNP_IRX_SIX_ZHX:-0.767000080584;RUNX1..3:-0.789806264762;EGR1..3:-0.798500166488;PAX3,7:-0.807317084325;MAFB:-0.830812623027;AR:-0.832046607308;NFIL3:-0.861987988666;ESR1:-0.89739244168;TFAP4:-0.910920073151;EBF1:-0.912646762259;RORA:-0.922845573486;TLX2:-0.941591342876;ATF2:-0.961215164228;CRX:-0.983135703653;STAT1,3:-1.04868203195;ATF6:-1.07317906982;HAND1,2:-1.0908046563;HOX{A6,A7,B6,B7}:-1.09106736843;NR5A1,2:-1.13524629415;NANOG{mouse}:-1.17473964516;NKX2-3_NKX2-5:-1.30664046729;RXR{A,B,G}_{NR1H2,PPAR}dimers:-1.32163118246;NANOG:-1.36099086118;TGIF1:-1.44486440394;DBP:-1.44829823078;SMAD1..7,9:-1.61821613997;ZNF238:-1.74745366623 | |top_motifs=ZBTB16:1.9410127768;UFEwm:1.42020842842;bHLH_family:1.36608134594;ALX4:1.16637654678;AIRE:1.00542013034;E2F1..5:1.0036815997;FOXQ1:1.00161659966;BPTF:0.962569422217;FOX{I1,J2}:0.954549016019;NFE2L1:0.94899217403;NKX2-1,4:0.907491277775;HES1:0.887493815978;PITX1..3:0.882767553229;PAX6:0.841438714759;ARID5B:0.834997262615;GATA4:0.818723207432;TEAD1:0.799566868263;TFDP1:0.794229063103;ONECUT1,2:0.726388951326;NKX3-1:0.711223002687;CDX1,2,4:0.692131338317;ELK1,4_GABP{A,B1}:0.663165505419;EVI1:0.6597704156;GZF1:0.618394808004;POU2F1..3:0.601796625797;HMGA1,2:0.600732421524;NKX2-2,8:0.589875282286;MYB:0.569870208251;MYOD1:0.550018512124;PAX8:0.540905320469;ZIC1..3:0.533111513046;PAX4:0.521182814049;ZBTB6:0.519128813536;HIF1A:0.514807095924;EP300:0.500490075411;TLX1..3_NFIC{dimer}:0.458122991684;PRDM1:0.456878442751;CDC5L:0.435117097544;GCM1,2:0.398031930797;HOX{A5,B5}:0.397224782708;FOXM1:0.390575136777;HMX1:0.384042158077;IKZF1:0.371243862457;ZNF384:0.357313508644;FOXP1:0.323212458363;TBX4,5:0.298725066801;FOXD3:0.276680380656;NRF1:0.264653097238;TEF:0.251859387135;NFY{A,B,C}:0.233894955411;FOS_FOS{B,L1}_JUN{B,D}:0.228417120828;YY1:0.224533481944;FOX{D1,D2}:0.219524492618;IRF7:0.20541034471;ZEB1:0.199092483485;PPARG:0.18637112272;TOPORS:0.181023777928;BACH2:0.177670742176;KLF4:0.171444931506;ZNF143:0.165437990489;HSF1,2:0.164326546625;SNAI1..3:0.159972050062;NR6A1:0.156990554257;RXR{A,B,G}:0.154584954641;POU3F1..4:0.152738098329;IRF1,2:0.143973265482;HOXA9_MEIS1:0.135432147472;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.130254600402;ALX1:0.129110296976;TBP:0.116941469408;STAT2,4,6:0.109650918609;GTF2A1,2:0.0985271741668;CEBPA,B_DDIT3:0.0974352634715;HOX{A4,D4}:0.095155943444;FOXL1:0.0939191847631;HLF:0.0811589302952;FOXO1,3,4:0.0691392346063;RFX1:0.0528013319559;EN1,2:-0.000427602751116;POU1F1:-0.00319552301663;PAX5:-0.0151409299124;RXRA_VDR{dimer}:-0.0196443145096;VSX1,2:-0.0262523799572;NFATC1..3:-0.0591485214254;LHX3,4:-0.0621625634897;IKZF2:-0.0630903444712;REST:-0.0684297916592;GFI1:-0.0744203744778;RBPJ:-0.0788864450169;TP53:-0.084946786714;LEF1_TCF7_TCF7L1,2:-0.11509564432;T:-0.117432042703;ATF4:-0.126278894066;POU5F1:-0.131105106744;NR3C1:-0.156184129237;XCPE1{core}:-0.159694057542;LMO2:-0.172428363161;TAL1_TCF{3,4,12}:-0.178434489979;BREu{core}:-0.178837431279;STAT5{A,B}:-0.185348275677;ELF1,2,4:-0.189981017306;FOXA2:-0.192109979197;HNF1A:-0.192609142867;ESRRA:-0.19727517054;NKX3-2:-0.199705900911;MYBL2:-0.199929796193;NFKB1_REL_RELA:-0.202697328511;NKX6-1,2:-0.207673937638;ATF5_CREB3:-0.211743590953;SP1:-0.218407139932;POU6F1:-0.235009474657;PDX1:-0.235224799196;HNF4A_NR2F1,2:-0.23646552254;SPIB:-0.258725383555;FOSL2:-0.259294510815;TFAP2B:-0.265428906463;NFE2:-0.271017499331;ZNF423:-0.271555779324;ZFP161:-0.280269796986;AHR_ARNT_ARNT2:-0.2924388907;ZNF148:-0.302465362314;SOX17:-0.306639660599;SOX{8,9,10}:-0.307440882047;SREBF1,2:-0.328720891957;GTF2I:-0.346099540064;NFIX:-0.351216599129;PBX1:-0.352663481808;MTE{core}:-0.356701143818;NR1H4:-0.359808164535;NHLH1,2:-0.366716292511;FOXP3:-0.368022086575;OCT4_SOX2{dimer}:-0.368937101326;ETS1,2:-0.37672733219;RREB1:-0.379458480536;MED-1{core}:-0.39061685089;CUX2:-0.397157604269;HIC1:-0.405183473467;SRF:-0.414391887663;SPI1:-0.421647947338;TFCP2:-0.449647598625;CREB1:-0.452925063023;SPZ1:-0.461511107028;NFE2L2:-0.4669215172;MYFfamily:-0.480590823942;DMAP1_NCOR{1,2}_SMARC:-0.487594509605;XBP1:-0.49053193917;GLI1..3:-0.510124748078;MEF2{A,B,C,D}:-0.526641615525;HBP1_HMGB_SSRP1_UBTF:-0.527514231803;GFI1B:-0.546216378479;MZF1:-0.571690020615;JUN:-0.586215069249;PRRX1,2:-0.595899091418;PAX2:-0.613222108791;MTF1:-0.635313653537;RFX2..5_RFXANK_RFXAP:-0.649149607995;FOXN1:-0.653553822232;PATZ1:-0.659628715676;FOX{F1,F2,J1}:-0.660700345338;MAZ:-0.671070725819;PAX1,9:-0.673320661506;SOX2:-0.693961179965;TFAP2{A,C}:-0.694838794108;SOX5:-0.730300967305;GATA6:-0.731872080972;ADNP_IRX_SIX_ZHX:-0.767000080584;RUNX1..3:-0.789806264762;EGR1..3:-0.798500166488;PAX3,7:-0.807317084325;MAFB:-0.830812623027;AR:-0.832046607308;NFIL3:-0.861987988666;ESR1:-0.89739244168;TFAP4:-0.910920073151;EBF1:-0.912646762259;RORA:-0.922845573486;TLX2:-0.941591342876;ATF2:-0.961215164228;CRX:-0.983135703653;STAT1,3:-1.04868203195;ATF6:-1.07317906982;HAND1,2:-1.0908046563;HOX{A6,A7,B6,B7}:-1.09106736843;NR5A1,2:-1.13524629415;NANOG{mouse}:-1.17473964516;NKX2-3_NKX2-5:-1.30664046729;RXR{A,B,G}_{NR1H2,PPAR}dimers:-1.32163118246;NANOG:-1.36099086118;TGIF1:-1.44486440394;DBP:-1.44829823078;SMAD1..7,9:-1.61821613997;ZNF238:-1.74745366623 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10437-106E5;search_select_hide=table117:FF:10437-106E5 | |||
}} | }} | ||
Latest revision as of 14:02, 3 June 2020
| Name: | papillary adenocarcinoma cell line:8505C |
|---|---|
| Species: | Human (Homo sapiens) |
| Library ID: | CNhs11716 |
| Sample type: | cell lines |
| Genomic View: | UCSC |
| RefEX: | Specific genes |
| CAGEd-oPOSSUM: | link |
| ZENBU report : | link |
| Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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| CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11716
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11716
| Novel motif | Logo | P-value |
|---|---|---|
| 1 | 1 | 0.701 |
| 10 | 10 | 0.184 |
| 100 | 100 | 0.0488 |
| 101 | 101 | 0.753 |
| 102 | 102 | 0.927 |
| 103 | 103 | 0.293 |
| 104 | 104 | 0.734 |
| 105 | 105 | 0.0154 |
| 106 | 106 | 0.507 |
| 107 | 107 | 0.923 |
| 108 | 108 | 0.676 |
| 109 | 109 | 0.259 |
| 11 | 11 | 0.714 |
| 110 | 110 | 0.706 |
| 111 | 111 | 0.525 |
| 112 | 112 | 0.794 |
| 113 | 113 | 0.0423 |
| 114 | 114 | 0.547 |
| 115 | 115 | 0.641 |
| 116 | 116 | 0.95 |
| 117 | 117 | 0.566 |
| 118 | 118 | 0.0326 |
| 119 | 119 | 0.852 |
| 12 | 12 | 0.0793 |
| 120 | 120 | 0.0829 |
| 121 | 121 | 0.861 |
| 122 | 122 | 0.55 |
| 123 | 123 | 0.886 |
| 124 | 124 | 0.0865 |
| 125 | 125 | 0.388 |
| 126 | 126 | 0.989 |
| 127 | 127 | 0.599 |
| 128 | 128 | 0.00731 |
| 129 | 129 | 0.805 |
| 13 | 13 | 0.0568 |
| 130 | 130 | 0.256 |
| 131 | 131 | 0.731 |
| 132 | 132 | 0.593 |
| 133 | 133 | 0.191 |
| 134 | 134 | 0.0122 |
| 135 | 135 | 0.856 |
| 136 | 136 | 0.0913 |
| 137 | 137 | 0.102 |
| 138 | 138 | 0.688 |
| 139 | 139 | 0.0291 |
| 14 | 14 | 0.248 |
| 140 | 140 | 0.787 |
| 141 | 141 | 0.983 |
| 142 | 142 | 0.955 |
| 143 | 143 | 0.0504 |
| 144 | 144 | 0.788 |
| 145 | 145 | 0.833 |
| 146 | 146 | 0.46 |
| 147 | 147 | 0.11 |
| 148 | 148 | 0.573 |
| 149 | 149 | 0.795 |
| 15 | 15 | 0.921 |
| 150 | 150 | 0.311 |
| 151 | 151 | 0.45 |
| 152 | 152 | 0.0329 |
| 153 | 153 | 0.302 |
| 154 | 154 | 0.773 |
| 155 | 155 | 0.355 |
| 156 | 156 | 0.448 |
| 157 | 157 | 0.525 |
| 158 | 158 | 0.0246 |
| 159 | 159 | 0.645 |
| 16 | 16 | 0.663 |
| 160 | 160 | 0.196 |
| 161 | 161 | 0.33 |
| 162 | 162 | 0.868 |
| 163 | 163 | 0.663 |
| 164 | 164 | 0.0387 |
| 165 | 165 | 0.329 |
| 166 | 166 | 0.866 |
| 167 | 167 | 0.0662 |
| 168 | 168 | 0.6 |
| 169 | 169 | 0.856 |
| 17 | 17 | 0.825 |
| 18 | 18 | 0.193 |
| 19 | 19 | 0.58 |
| 2 | 2 | 0.175 |
| 20 | 20 | 0.0388 |
| 21 | 21 | 0.00255 |
| 22 | 22 | 0.085 |
| 23 | 23 | 0.531 |
| 24 | 24 | 0.649 |
| 25 | 25 | 0.232 |
| 26 | 26 | 0.348 |
| 27 | 27 | 0.793 |
| 28 | 28 | 0.554 |
| 29 | 29 | 0.115 |
| 3 | 3 | 0.846 |
| 30 | 30 | 0.294 |
| 31 | 31 | 0.555 |
| 32 | 32 | 0.912 |
| 33 | 33 | 0.0425 |
| 34 | 34 | 0.0569 |
| 35 | 35 | 0.895 |
| 36 | 36 | 0.541 |
| 37 | 37 | 0.902 |
| 38 | 38 | 0.872 |
| 39 | 39 | 0.677 |
| 4 | 4 | 0.158 |
| 40 | 40 | 0.504 |
| 41 | 41 | 0.647 |
| 42 | 42 | 0.84 |
| 43 | 43 | 0.316 |
| 44 | 44 | 0.0536 |
| 45 | 45 | 0.229 |
| 46 | 46 | 0.749 |
| 47 | 47 | 0.987 |
| 48 | 48 | 0.913 |
| 49 | 49 | 0.0739 |
| 5 | 5 | 0.421 |
| 50 | 50 | 0.906 |
| 51 | 51 | 0.618 |
| 52 | 52 | 0.0795 |
| 53 | 53 | 0.142 |
| 54 | 54 | 0.746 |
| 55 | 55 | 0.995 |
| 56 | 56 | 0.665 |
| 57 | 57 | 0.176 |
| 58 | 58 | 0.605 |
| 59 | 59 | 0.557 |
| 6 | 6 | 0.784 |
| 60 | 60 | 0.175 |
| 61 | 61 | 0.773 |
| 62 | 62 | 0.661 |
| 63 | 63 | 0.506 |
| 64 | 64 | 0.572 |
| 65 | 65 | 0.464 |
| 66 | 66 | 0.94 |
| 67 | 67 | 0.554 |
| 68 | 68 | 0.926 |
| 69 | 69 | 0.335 |
| 7 | 7 | 0.62 |
| 70 | 70 | 0.0681 |
| 71 | 71 | 0.347 |
| 72 | 72 | 0.331 |
| 73 | 73 | 0.515 |
| 74 | 74 | 0.531 |
| 75 | 75 | 0.761 |
| 76 | 76 | 0.132 |
| 77 | 77 | 0.809 |
| 78 | 78 | 0.844 |
| 79 | 79 | 0.15 |
| 8 | 8 | 0.144 |
| 80 | 80 | 0.00308 |
| 81 | 81 | 0.948 |
| 82 | 82 | 0.1 |
| 83 | 83 | 0.967 |
| 84 | 84 | 0.182 |
| 85 | 85 | 0.3 |
| 86 | 86 | 0.236 |
| 87 | 87 | 0.159 |
| 88 | 88 | 0.867 |
| 89 | 89 | 0.909 |
| 9 | 9 | 0.176 |
| 90 | 90 | 0.595 |
| 91 | 91 | 0.798 |
| 92 | 92 | 0.992 |
| 93 | 93 | 0.109 |
| 94 | 94 | 0.509 |
| 95 | 95 | 0.466 |
| 96 | 96 | 0.118 |
| 97 | 97 | 0.715 |
| 98 | 98 | 0.963 |
| 99 | 99 | 0.0742 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11716
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
DOID:3112 papillary adenocarcinoma
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0104965 8505C cell sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000066 (epithelial cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
162 (cancer)
14566 (disease of cellular proliferation)
0050687 (cell type cancer)
7 (disease of anatomical entity)
305 (carcinoma)
299 (adenocarcinoma)
3112 (papillary adenocarcinoma)
UBERON: Anatomy
0000468 (multi-cellular organism)
0002046 (thyroid gland)
0004119 (endoderm-derived structure)
0010314 (structure with developmental contribution from neural crest)
0000062 (organ)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0002368 (endocrine gland)
0002530 (gland)
0010317 (germ layer / neural crest derived structure)
0000949 (endocrine system)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100297 (carcinoma cell line sample)
0101120 (epithelial cell line sample)
0103209 (anaplastic thyroid cancer cell line sample)
0101610 (thyroid cancer cell line sample)
0104965 (8505C cell sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
UBERON:0002532 (epiblast (generic))
UBERON:0006595 (presumptive endoderm)
UBERON:0007123 (pharyngeal pouch 2)
UBERON:0010316 (germ layer / neural crest)
