FF:10801-110I9: Difference between revisions
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{{f5samples | {{f5samples | ||
|ancestors_in_anatomy_facet= | |DRA_sample_Accession=CAGE@SAMD00005470 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |accession_numbers=CAGE;DRX007853;DRR008725;DRZ000150;DRZ001535;DRZ011500;DRZ012885 | ||
| | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000255 | |||
|ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:14566,DOID:0060083,DOID:1240,DOID:1036,DOID:8692 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100737,FF:0102580,FF:0101035,FF:0100740,FF:0104137 | |||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
|expression_enrichment_score | |||
|fonse_cell_line=FF:0101035 | |fonse_cell_line=FF:0101035 | ||
|fonse_cell_line_closure=FF:0101035 | |fonse_cell_line_closure=FF:0101035 | ||
Line 35: | Line 41: | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/chronic%2520myeloblastic%2520leukemia%2520%2528CML%2529%2520cell%2520line%253aKCL-22.CNhs11886.10801-110I9.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/chronic%2520myeloblastic%2520leukemia%2520%2528CML%2529%2520cell%2520line%253aKCL-22.CNhs11886.10801-110I9.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/chronic%2520myeloblastic%2520leukemia%2520%2528CML%2529%2520cell%2520line%253aKCL-22.CNhs11886.10801-110I9.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/chronic%2520myeloblastic%2520leukemia%2520%2528CML%2529%2520cell%2520line%253aKCL-22.CNhs11886.10801-110I9.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/chronic%2520myeloblastic%2520leukemia%2520%2528CML%2529%2520cell%2520line%253aKCL-22.CNhs11886.10801-110I9.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10801-110I9 | |id=FF:10801-110I9 | ||
|is_a=EFO:0002091;;FF: | |is_a=EFO:0002091;;FF:0000210;;FF:0104137 | ||
|is_obsolete= | |||
|library_id=CNhs11886 | |||
|library_id_phase_based=2:CNhs11886 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10801 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10801 | |||
|name=chronic myeloblastic leukemia (CML) cell line:KCL-22 | |name=chronic myeloblastic leukemia (CML) cell line:KCL-22 | ||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
Line 42: | Line 60: | ||
|profile_cagescan=,,, | |profile_cagescan=,,, | ||
|profile_hcage=CNhs11886,LSID830,release010,COMPLETED | |profile_hcage=CNhs11886,LSID830,release010,COMPLETED | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq=,,, | |profile_srnaseq=,,, | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0.0442760991774771,0,0,0,-0.0969920822079765,0.0633259478784096,-0.0232190967377284,0.313550557126594,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0583103220311033,0,0,0,0,0,0.255350791813207,0,0,0.276943168307013,0,0,0,0,0,0,0.204949879042937,0,0,0,0.167595185212925,0,0.0128029189109715,0.167595185212925,0,0,0,0,0,0,0,-0.0242150211128343,0,0,0,0,0,0,0,0.25631632683866,0,0,-0.0340176793346874,0,0,0,0,0,0,0,0,0.118582313979419,0,0.251614201468362,0,0,0.118582313979419,0,0,0,0,0.0837975926064625,0,0.12549234259032,0,0,0,-0.019613922371696,0.0316629739392048,0,0,-0.0584468268118252,0.144819500105811,0.0316629739392048,0,0.0592911569897095,0,0.190187381645628,0.209747496524322,0,0,0,0,0,0,0.0633259478784096,0,0,0,0,0,0,0,0,0,0,-0.096373593922461,0.0633259478784096,0,0,-0.0306358713632606,-0.0580718685799035,0,0,0.0803692818333655,0,0,0 | |||
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| |||
|rna_box=110 | |rna_box=110 | ||
|rna_catalog_number= | |rna_catalog_number= | ||
Line 57: | Line 78: | ||
|rna_weight_ug=20.88153 | |rna_weight_ug=20.88153 | ||
|sample_age=28 | |sample_age=28 | ||
|sample_category=cell lines | |||
|sample_cell_catalog=jcrb1317 | |sample_cell_catalog=jcrb1317 | ||
|sample_cell_line=KCL-22 | |sample_cell_line=KCL-22 | ||
Line 69: | Line 91: | ||
|sample_ethnicity=J | |sample_ethnicity=J | ||
|sample_experimental_condition= | |sample_experimental_condition= | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;5.87990559079812e-246!GO:0043227;membrane-bound organelle;5.25778696900095e-218!GO:0043231;intracellular membrane-bound organelle;1.12176620976705e-217!GO:0043226;organelle;2.4731007432217e-203!GO:0043229;intracellular organelle;7.25465093448755e-203!GO:0005737;cytoplasm;6.63637024685857e-167!GO:0044422;organelle part;1.90712780375646e-151!GO:0044446;intracellular organelle part;8.5950460184614e-150!GO:0044444;cytoplasmic part;6.89836815964827e-122!GO:0044237;cellular metabolic process;6.29319540324883e-116!GO:0032991;macromolecular complex;9.76215724380027e-113!GO:0044238;primary metabolic process;1.31481198260758e-112!GO:0043170;macromolecule metabolic process;3.61821376947868e-104!GO:0005634;nucleus;6.48522535030857e-100!GO:0030529;ribonucleoprotein complex;7.73462406706473e-98!GO:0043233;organelle lumen;4.33134130626999e-92!GO:0031974;membrane-enclosed lumen;4.33134130626999e-92!GO:0044428;nuclear part;5.1982275625457e-92!GO:0003723;RNA binding;1.66916303526576e-81!GO:0005739;mitochondrion;1.12502788539934e-79!GO:0005515;protein binding;3.54691657443712e-68!GO:0043283;biopolymer metabolic process;2.93845739575174e-64!GO:0006396;RNA processing;1.23946807540316e-60!GO:0006412;translation;9.71968821421262e-60!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;7.63830207930306e-58!GO:0010467;gene expression;2.91593661233502e-57!GO:0005840;ribosome;5.32717141803102e-57!GO:0031981;nuclear lumen;1.5014735256947e-56!GO:0043234;protein complex;4.00580284507308e-56!GO:0044429;mitochondrial part;2.25165243235476e-55!GO:0019538;protein metabolic process;5.16054128536682e-53!GO:0003735;structural constituent of ribosome;6.8082065937027e-50!GO:0044249;cellular biosynthetic process;1.25976160588988e-49!GO:0009058;biosynthetic process;1.79130263908223e-49!GO:0031967;organelle envelope;4.76225398619852e-49!GO:0031975;envelope;1.22601702365446e-48!GO:0016071;mRNA metabolic process;4.020443647166e-48!GO:0044267;cellular protein metabolic process;1.82189325665976e-47!GO:0044260;cellular macromolecule metabolic process;3.82788528154928e-47!GO:0031090;organelle membrane;5.9627359474099e-46!GO:0009059;macromolecule biosynthetic process;1.9640316140777e-45!GO:0008380;RNA splicing;3.19976811248988e-43!GO:0033279;ribosomal subunit;5.15285764439325e-42!GO:0016043;cellular component organization and biogenesis;7.67786895649001e-42!GO:0033036;macromolecule localization;1.18623597072776e-41!GO:0006259;DNA metabolic process;1.3404622410516e-41!GO:0006397;mRNA processing;2.06771919296616e-41!GO:0015031;protein transport;1.00698392881932e-40!GO:0005829;cytosol;9.15218026613037e-38!GO:0045184;establishment of protein localization;1.17171030013586e-37!GO:0008104;protein localization;2.26703699939368e-37!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.08987804882844e-36!GO:0065003;macromolecular complex assembly;3.42752993176669e-36!GO:0046907;intracellular transport;1.0593134241558e-35!GO:0005654;nucleoplasm;7.04634859389345e-35!GO:0003676;nucleic acid binding;2.18412200695248e-34!GO:0005740;mitochondrial envelope;3.19482558077364e-34!GO:0006996;organelle organization and biogenesis;9.58141760791288e-34!GO:0019866;organelle inner membrane;1.14983936374402e-32!GO:0007049;cell cycle;1.82180451184086e-32!GO:0031966;mitochondrial membrane;9.22731297515712e-32!GO:0022607;cellular component assembly;2.56105446427553e-31!GO:0006886;intracellular protein transport;4.83378016712262e-31!GO:0005681;spliceosome;6.38247477738977e-31!GO:0043228;non-membrane-bound organelle;1.34046307009563e-29!GO:0043232;intracellular non-membrane-bound organelle;1.34046307009563e-29!GO:0005743;mitochondrial inner membrane;1.80526925695527e-29!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.98713082877659e-29!GO:0000166;nucleotide binding;3.01077516866133e-29!GO:0016070;RNA metabolic process;3.1334183174874e-27!GO:0044451;nucleoplasm part;9.05749851292513e-27!GO:0022402;cell cycle process;7.90198392261746e-26!GO:0051649;establishment of cellular localization;3.13177725842645e-25!GO:0031980;mitochondrial lumen;5.50079403397038e-25!GO:0005759;mitochondrial matrix;5.50079403397038e-25!GO:0006974;response to DNA damage stimulus;5.50079403397038e-25!GO:0051641;cellular localization;1.45306382168311e-24!GO:0006119;oxidative phosphorylation;2.26604123491297e-24!GO:0044455;mitochondrial membrane part;2.34597744073315e-24!GO:0044445;cytosolic part;3.48900668766672e-24!GO:0000278;mitotic cell cycle;1.48682307724968e-23!GO:0005730;nucleolus;3.86357401694845e-23!GO:0016462;pyrophosphatase activity;6.59638399615999e-23!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;7.5272797096891e-23!GO:0016817;hydrolase activity, acting on acid anhydrides;1.08717661713343e-22!GO:0006281;DNA repair;8.1298359738442e-22!GO:0017111;nucleoside-triphosphatase activity;8.70179631271162e-22!GO:0015935;small ribosomal subunit;9.43659628161215e-22!GO:0015934;large ribosomal subunit;1.95464806559129e-21!GO:0005694;chromosome;3.37448638009334e-21!GO:0032553;ribonucleotide binding;2.21593510882807e-20!GO:0032555;purine ribonucleotide binding;2.21593510882807e-20!GO:0017076;purine nucleotide binding;5.96612862019817e-20!GO:0051276;chromosome organization and biogenesis;6.07642041473942e-20!GO:0022618;protein-RNA complex assembly;1.21372115798958e-19!GO:0016874;ligase activity;2.73240421141171e-19!GO:0005524;ATP binding;4.58345609991188e-19!GO:0005746;mitochondrial respiratory chain;1.05564035036431e-18!GO:0032559;adenyl ribonucleotide binding;1.253790096059e-18!GO:0044427;chromosomal part;1.35927804235571e-18!GO:0044265;cellular macromolecule catabolic process;1.50652596337505e-18!GO:0006457;protein folding;1.86681048215564e-18!GO:0006512;ubiquitin cycle;2.7102307652076e-18!GO:0000087;M phase of mitotic cell cycle;3.79565478371373e-18!GO:0030554;adenyl nucleotide binding;5.64981685051615e-18!GO:0022403;cell cycle phase;5.72765394395638e-18!GO:0009719;response to endogenous stimulus;8.26894874644495e-18!GO:0007067;mitosis;1.07662385296631e-17!GO:0042254;ribosome biogenesis and assembly;1.38767964171779e-17!GO:0048770;pigment granule;4.73724058110423e-17!GO:0042470;melanosome;4.73724058110423e-17!GO:0043412;biopolymer modification;5.53740327926074e-17!GO:0006605;protein targeting;5.74104787110864e-17!GO:0005761;mitochondrial ribosome;5.74104787110864e-17!GO:0000313;organellar ribosome;5.74104787110864e-17!GO:0050136;NADH dehydrogenase (quinone) activity;7.80169814142024e-17!GO:0003954;NADH dehydrogenase activity;7.80169814142024e-17!GO:0008137;NADH dehydrogenase (ubiquinone) activity;7.80169814142024e-17!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.1159021831738e-16!GO:0051301;cell division;1.23467349581375e-16!GO:0051186;cofactor metabolic process;1.4197816900105e-16!GO:0006260;DNA replication;1.74676560525201e-16!GO:0043285;biopolymer catabolic process;2.22113199896994e-16!GO:0012505;endomembrane system;2.83136696997948e-16!GO:0008134;transcription factor binding;3.61170104826289e-16!GO:0000398;nuclear mRNA splicing, via spliceosome;3.86496119677409e-16!GO:0000375;RNA splicing, via transesterification reactions;3.86496119677409e-16!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;3.86496119677409e-16!GO:0006325;establishment and/or maintenance of chromatin architecture;3.9228892141953e-16!GO:0009057;macromolecule catabolic process;4.43548841247778e-16!GO:0044248;cellular catabolic process;6.18390638469789e-16!GO:0000502;proteasome complex (sensu Eukaryota);8.59995122920389e-16!GO:0016887;ATPase activity;1.02111076996869e-15!GO:0044453;nuclear membrane part;1.22416443024228e-15!GO:0005635;nuclear envelope;1.4225751513814e-15!GO:0006323;DNA packaging;1.6943686730516e-15!GO:0042623;ATPase activity, coupled;2.24823784782385e-15!GO:0012501;programmed cell death;3.31728851197846e-15!GO:0006915;apoptosis;3.31728851197846e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);4.58483748755515e-15!GO:0008135;translation factor activity, nucleic acid binding;4.6579802260375e-15!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);7.72414607200859e-15!GO:0031965;nuclear membrane;7.76880731387556e-15!GO:0030964;NADH dehydrogenase complex (quinone);8.34993646194555e-15!GO:0045271;respiratory chain complex I;8.34993646194555e-15!GO:0005747;mitochondrial respiratory chain complex I;8.34993646194555e-15!GO:0042775;organelle ATP synthesis coupled electron transport;8.34993646194555e-15!GO:0042773;ATP synthesis coupled electron transport;8.34993646194555e-15!GO:0016604;nuclear body;9.18507730861922e-15!GO:0051726;regulation of cell cycle;9.43584580711806e-15!GO:0006464;protein modification process;1.30898164390613e-14!GO:0051603;proteolysis involved in cellular protein catabolic process;1.95095582973602e-14!GO:0006511;ubiquitin-dependent protein catabolic process;2.12666144089337e-14!GO:0000279;M phase;2.17154127144428e-14!GO:0019941;modification-dependent protein catabolic process;2.30885059653019e-14!GO:0043632;modification-dependent macromolecule catabolic process;2.30885059653019e-14!GO:0006732;coenzyme metabolic process;2.59322987647601e-14!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;2.61874573724665e-14!GO:0000074;regulation of progression through cell cycle;2.91209389485135e-14!GO:0044257;cellular protein catabolic process;3.76049963675866e-14!GO:0005783;endoplasmic reticulum;4.16472427287875e-14!GO:0044432;endoplasmic reticulum part;1.31542043588519e-13!GO:0006913;nucleocytoplasmic transport;1.43739668245726e-13!GO:0008219;cell death;1.79691931699252e-13!GO:0016265;death;1.79691931699252e-13!GO:0043687;post-translational protein modification;3.97770314925609e-13!GO:0051169;nuclear transport;4.23202222090066e-13!GO:0005643;nuclear pore;5.03909212965909e-13!GO:0050657;nucleic acid transport;5.39335414837837e-13!GO:0051236;establishment of RNA localization;5.39335414837837e-13!GO:0050658;RNA transport;5.39335414837837e-13!GO:0065002;intracellular protein transport across a membrane;5.92947017016296e-13!GO:0006399;tRNA metabolic process;6.29129536868843e-13!GO:0006403;RNA localization;8.1150343978683e-13!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.25472630698646e-12!GO:0006413;translational initiation;4.03386052845849e-12!GO:0003743;translation initiation factor activity;4.52787547434031e-12!GO:0030163;protein catabolic process;4.95986132227646e-12!GO:0051082;unfolded protein binding;5.11745846655922e-12!GO:0009259;ribonucleotide metabolic process;5.55183591898042e-12!GO:0004386;helicase activity;6.30240838574119e-12!GO:0006364;rRNA processing;7.71178495313683e-12!GO:0006163;purine nucleotide metabolic process;8.92087313471732e-12!GO:0000785;chromatin;9.20310846783643e-12!GO:0016072;rRNA metabolic process;1.32122305928645e-11!GO:0006446;regulation of translational initiation;1.40041983415161e-11!GO:0065004;protein-DNA complex assembly;1.71853250569086e-11!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;2.0702065517841e-11!GO:0016568;chromatin modification;2.23706593787292e-11!GO:0008565;protein transporter activity;2.29768967769679e-11!GO:0016607;nuclear speck;2.58958922951562e-11!GO:0006164;purine nucleotide biosynthetic process;2.65074392242234e-11!GO:0046930;pore complex;5.87388420290812e-11!GO:0051028;mRNA transport;6.08390583407284e-11!GO:0017038;protein import;6.91895851789013e-11!GO:0009260;ribonucleotide biosynthetic process;7.27521813952591e-11!GO:0008026;ATP-dependent helicase activity;8.12496412724588e-11!GO:0006366;transcription from RNA polymerase II promoter;9.69174511532835e-11!GO:0009150;purine ribonucleotide metabolic process;1.01396305792638e-10!GO:0016740;transferase activity;1.17209144316273e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.78300702655541e-10!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.79152997508367e-10!GO:0006333;chromatin assembly or disassembly;1.87436522394796e-10!GO:0050794;regulation of cellular process;2.51111621616369e-10!GO:0048193;Golgi vesicle transport;2.61595162980362e-10!GO:0009152;purine ribonucleotide biosynthetic process;3.08261465364901e-10!GO:0003712;transcription cofactor activity;3.39423178552927e-10!GO:0006461;protein complex assembly;4.6898799699982e-10!GO:0016192;vesicle-mediated transport;4.82185170711168e-10!GO:0042175;nuclear envelope-endoplasmic reticulum network;5.27169889268024e-10!GO:0006793;phosphorus metabolic process;5.27169889268024e-10!GO:0006796;phosphate metabolic process;5.27169889268024e-10!GO:0051188;cofactor biosynthetic process;5.59301898848983e-10!GO:0030532;small nuclear ribonucleoprotein complex;6.28774409423786e-10!GO:0005789;endoplasmic reticulum membrane;1.11566785140212e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.20914618058054e-09!GO:0042981;regulation of apoptosis;1.23745819063552e-09!GO:0009055;electron carrier activity;1.3042511721597e-09!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.48601692829092e-09!GO:0004812;aminoacyl-tRNA ligase activity;1.48601692829092e-09!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.48601692829092e-09!GO:0043067;regulation of programmed cell death;1.89053036967182e-09!GO:0019829;cation-transporting ATPase activity;2.40780940599004e-09!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;2.49311127394098e-09!GO:0009056;catabolic process;2.73011172997797e-09!GO:0051246;regulation of protein metabolic process;3.36049477947887e-09!GO:0043038;amino acid activation;3.38155479738949e-09!GO:0006418;tRNA aminoacylation for protein translation;3.38155479738949e-09!GO:0043039;tRNA aminoacylation;3.38155479738949e-09!GO:0009199;ribonucleoside triphosphate metabolic process;3.69363526597692e-09!GO:0009141;nucleoside triphosphate metabolic process;4.26115419872842e-09!GO:0009142;nucleoside triphosphate biosynthetic process;4.88594259646e-09!GO:0009201;ribonucleoside triphosphate biosynthetic process;4.88594259646e-09!GO:0009060;aerobic respiration;4.97446428443379e-09!GO:0007005;mitochondrion organization and biogenesis;5.00541316136234e-09!GO:0015986;ATP synthesis coupled proton transport;6.10232981984914e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;6.10232981984914e-09!GO:0009205;purine ribonucleoside triphosphate metabolic process;6.94269308614212e-09!GO:0009144;purine nucleoside triphosphate metabolic process;6.94269308614212e-09!GO:0016779;nucleotidyltransferase activity;8.01777191089711e-09!GO:0048523;negative regulation of cellular process;8.93345825443737e-09!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;9.41795068638271e-09!GO:0009145;purine nucleoside triphosphate biosynthetic process;9.41795068638271e-09!GO:0008639;small protein conjugating enzyme activity;9.66324284307974e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.50882007616475e-08!GO:0006261;DNA-dependent DNA replication;1.81301180197358e-08!GO:0004842;ubiquitin-protein ligase activity;2.15115462540146e-08!GO:0019787;small conjugating protein ligase activity;2.27513680217646e-08!GO:0009108;coenzyme biosynthetic process;2.3717752059496e-08!GO:0045333;cellular respiration;3.1449522698713e-08!GO:0043566;structure-specific DNA binding;3.35842063170148e-08!GO:0005793;ER-Golgi intermediate compartment;5.13452063065691e-08!GO:0016310;phosphorylation;5.31656289167407e-08!GO:0051170;nuclear import;6.70456692871137e-08!GO:0005794;Golgi apparatus;7.06677043216355e-08!GO:0046034;ATP metabolic process;7.71741602200147e-08!GO:0003899;DNA-directed RNA polymerase activity;7.71741602200147e-08!GO:0016787;hydrolase activity;7.98578114086244e-08!GO:0006754;ATP biosynthetic process;8.24976680761384e-08!GO:0006753;nucleoside phosphate metabolic process;8.24976680761384e-08!GO:0009117;nucleotide metabolic process;1.35195601687366e-07!GO:0019222;regulation of metabolic process;1.42514488390182e-07!GO:0006334;nucleosome assembly;1.50593324261366e-07!GO:0005819;spindle;1.5327519944608e-07!GO:0006606;protein import into nucleus;1.62998935707641e-07!GO:0006099;tricarboxylic acid cycle;1.68115808963504e-07!GO:0046356;acetyl-CoA catabolic process;1.68115808963504e-07!GO:0015078;hydrogen ion transmembrane transporter activity;1.73890359913473e-07!GO:0043069;negative regulation of programmed cell death;1.80341314023438e-07!GO:0003697;single-stranded DNA binding;1.92433715725053e-07!GO:0016469;proton-transporting two-sector ATPase complex;2.0331417446592e-07!GO:0043066;negative regulation of apoptosis;2.07098057874789e-07!GO:0050789;regulation of biological process;2.445667285479e-07!GO:0006752;group transfer coenzyme metabolic process;2.9109153597515e-07!GO:0031497;chromatin assembly;3.04832897503599e-07!GO:0006084;acetyl-CoA metabolic process;3.17562809186341e-07!GO:0006916;anti-apoptosis;3.2192125798737e-07!GO:0007249;I-kappaB kinase/NF-kappaB cascade;3.35158414189732e-07!GO:0000245;spliceosome assembly;3.45512027397803e-07!GO:0016881;acid-amino acid ligase activity;3.59788370357728e-07!GO:0048519;negative regulation of biological process;3.81054426926334e-07!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;4.21733596385494e-07!GO:0005667;transcription factor complex;4.78392390424964e-07!GO:0051329;interphase of mitotic cell cycle;4.98225887678544e-07!GO:0045259;proton-transporting ATP synthase complex;5.13766692707969e-07!GO:0003713;transcription coactivator activity;7.23830078308879e-07!GO:0051325;interphase;8.014476946224e-07!GO:0005839;proteasome core complex (sensu Eukaryota);8.10026089560265e-07!GO:0045786;negative regulation of progression through cell cycle;9.9810902275088e-07!GO:0009109;coenzyme catabolic process;1.22787052849181e-06!GO:0032446;protein modification by small protein conjugation;1.337818569333e-06!GO:0048475;coated membrane;1.59604741285745e-06!GO:0030117;membrane coat;1.59604741285745e-06!GO:0000775;chromosome, pericentric region;1.66982358237483e-06!GO:0000075;cell cycle checkpoint;2.17077938567988e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;2.31881341244855e-06!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;2.40376148338088e-06!GO:0016567;protein ubiquitination;2.97295826909314e-06!GO:0015630;microtubule cytoskeleton;3.24982854070893e-06!GO:0005762;mitochondrial large ribosomal subunit;3.25358267915363e-06!GO:0000315;organellar large ribosomal subunit;3.25358267915363e-06!GO:0004298;threonine endopeptidase activity;3.26950376688413e-06!GO:0005768;endosome;3.27540752931745e-06!GO:0051427;hormone receptor binding;3.50597856557988e-06!GO:0016491;oxidoreductase activity;4.16828766375787e-06!GO:0003724;RNA helicase activity;5.2008808043542e-06!GO:0006613;cotranslational protein targeting to membrane;5.63378888395392e-06!GO:0006888;ER to Golgi vesicle-mediated transport;5.9165815713264e-06!GO:0016563;transcription activator activity;6.42412725213591e-06!GO:0051187;cofactor catabolic process;6.55889436237684e-06!GO:0005788;endoplasmic reticulum lumen;6.7476613464269e-06!GO:0044452;nucleolar part;6.99948142959898e-06!GO:0035257;nuclear hormone receptor binding;7.33770703385357e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;7.78481456953249e-06!GO:0007051;spindle organization and biogenesis;8.35618612680991e-06!GO:0008094;DNA-dependent ATPase activity;8.43095113398247e-06!GO:0006401;RNA catabolic process;8.82468609806764e-06!GO:0000151;ubiquitin ligase complex;9.36690707640368e-06!GO:0016741;transferase activity, transferring one-carbon groups;9.5976622926036e-06!GO:0006950;response to stress;9.68876325200553e-06!GO:0008168;methyltransferase activity;9.85864977870667e-06!GO:0005815;microtubule organizing center;1.20529498013625e-05!GO:0006302;double-strand break repair;1.36771476007158e-05!GO:0051168;nuclear export;1.38743930599738e-05!GO:0005773;vacuole;1.4001208068026e-05!GO:0030880;RNA polymerase complex;1.44474170568633e-05!GO:0008654;phospholipid biosynthetic process;1.49966741949412e-05!GO:0000314;organellar small ribosomal subunit;1.56487064982999e-05!GO:0005763;mitochondrial small ribosomal subunit;1.56487064982999e-05!GO:0031323;regulation of cellular metabolic process;1.68046267532697e-05!GO:0006839;mitochondrial transport;1.7348821640119e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;1.76865463399369e-05!GO:0016853;isomerase activity;1.86497735312961e-05!GO:0005813;centrosome;1.92709129482791e-05!GO:0043623;cellular protein complex assembly;1.94070502057458e-05!GO:0031324;negative regulation of cellular metabolic process;1.9798856398907e-05!GO:0006352;transcription initiation;1.98860927206474e-05!GO:0005657;replication fork;2.11513687773041e-05!GO:0000323;lytic vacuole;2.17082495881565e-05!GO:0005764;lysosome;2.17082495881565e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;2.30630769603494e-05!GO:0006383;transcription from RNA polymerase III promoter;2.39997153959631e-05!GO:0045454;cell redox homeostasis;2.98981038575579e-05!GO:0016363;nuclear matrix;3.11830039305869e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;3.30078670803875e-05!GO:0015399;primary active transmembrane transporter activity;3.30078670803875e-05!GO:0019752;carboxylic acid metabolic process;3.35828601759954e-05!GO:0009165;nucleotide biosynthetic process;3.45875611806686e-05!GO:0007243;protein kinase cascade;3.46460631911853e-05!GO:0055029;nuclear DNA-directed RNA polymerase complex;3.62034940234302e-05!GO:0000428;DNA-directed RNA polymerase complex;3.62034940234302e-05!GO:0006082;organic acid metabolic process;3.91126669073081e-05!GO:0043021;ribonucleoprotein binding;4.1995527213449e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;4.34805344247562e-05!GO:0030120;vesicle coat;4.66200934639952e-05!GO:0030662;coated vesicle membrane;4.66200934639952e-05!GO:0008033;tRNA processing;5.12266980762825e-05!GO:0003690;double-stranded DNA binding;5.55884612542065e-05!GO:0005770;late endosome;5.58362816505296e-05!GO:0006091;generation of precursor metabolites and energy;5.66107962955479e-05!GO:0006310;DNA recombination;6.07183332854676e-05!GO:0006626;protein targeting to mitochondrion;6.22036573473547e-05!GO:0031968;organelle outer membrane;6.36764221008439e-05!GO:0003678;DNA helicase activity;6.49179324869449e-05!GO:0003684;damaged DNA binding;6.55868515964258e-05!GO:0016564;transcription repressor activity;6.56210570073392e-05!GO:0019867;outer membrane;7.03366728576361e-05!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;7.32639211112744e-05!GO:0003924;GTPase activity;8.68543942060756e-05!GO:0019899;enzyme binding;9.5484096990252e-05!GO:0005741;mitochondrial outer membrane;0.000103859320662461!GO:0006350;transcription;0.000120282353759639!GO:0006414;translational elongation;0.000120404335889914!GO:0004527;exonuclease activity;0.000124142611561842!GO:0043681;protein import into mitochondrion;0.000124871837133673!GO:0006402;mRNA catabolic process;0.000132472535164932!GO:0003729;mRNA binding;0.000142921454902339!GO:0005525;GTP binding;0.000145263826508967!GO:0000059;protein import into nucleus, docking;0.00015446959842126!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00016291329914195!GO:0006520;amino acid metabolic process;0.000164837107984802!GO:0007088;regulation of mitosis;0.000173512500722147!GO:0000786;nucleosome;0.000173823634841733!GO:0065007;biological regulation;0.000186024477985835!GO:0030867;rough endoplasmic reticulum membrane;0.00019285562465147!GO:0008186;RNA-dependent ATPase activity;0.00019983936080464!GO:0006417;regulation of translation;0.000201271726435961!GO:0031988;membrane-bound vesicle;0.000223770690691076!GO:0005885;Arp2/3 protein complex;0.000223770690691076!GO:0007059;chromosome segregation;0.000236114673817649!GO:0009892;negative regulation of metabolic process;0.00026503959596771!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000267667031317387!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000287572072441901!GO:0005798;Golgi-associated vesicle;0.000288849519977356!GO:0006612;protein targeting to membrane;0.000311728503176914!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000330354291298139!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000342393643205741!GO:0005637;nuclear inner membrane;0.000400448428481985!GO:0015992;proton transport;0.000406992881159216!GO:0006818;hydrogen transport;0.000427352436712704!GO:0015980;energy derivation by oxidation of organic compounds;0.000428726648323947!GO:0000082;G1/S transition of mitotic cell cycle;0.000432171106816974!GO:0044440;endosomal part;0.0004328174251061!GO:0010008;endosome membrane;0.0004328174251061!GO:0016023;cytoplasmic membrane-bound vesicle;0.000437794393171612!GO:0046483;heterocycle metabolic process;0.000450691497956542!GO:0043492;ATPase activity, coupled to movement of substances;0.000458895184280052!GO:0007006;mitochondrial membrane organization and biogenesis;0.000466312174387606!GO:0065009;regulation of a molecular function;0.000467139478864451!GO:0000776;kinetochore;0.000476417306060045!GO:0010468;regulation of gene expression;0.000486054878782099!GO:0016481;negative regulation of transcription;0.000490703929415435!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.000492259507684223!GO:0031982;vesicle;0.000502974333852908!GO:0016251;general RNA polymerase II transcription factor activity;0.000509703385706493!GO:0046474;glycerophospholipid biosynthetic process;0.000509703385706493!GO:0004518;nuclease activity;0.000522611075485132!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000523755003223216!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000540500029147705!GO:0004004;ATP-dependent RNA helicase activity;0.000584099213522373!GO:0051052;regulation of DNA metabolic process;0.000602011152165261!GO:0016281;eukaryotic translation initiation factor 4F complex;0.000606271758330805!GO:0003682;chromatin binding;0.000671421932749328!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000722588119031841!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00079661608000565!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00079661608000565!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00079661608000565!GO:0051920;peroxiredoxin activity;0.000892970268026344!GO:0008632;apoptotic program;0.000948363034407777!GO:0007093;mitotic cell cycle checkpoint;0.000986493833108724!GO:0006367;transcription initiation from RNA polymerase II promoter;0.000986674742443054!GO:0005684;U2-dependent spliceosome;0.000997124016654338!GO:0006405;RNA export from nucleus;0.00104314202241921!GO:0031410;cytoplasmic vesicle;0.00108386042928688!GO:0006519;amino acid and derivative metabolic process;0.00111737618659191!GO:0044262;cellular carbohydrate metabolic process;0.00114428049960578!GO:0031326;regulation of cellular biosynthetic process;0.00116465908389594!GO:0051087;chaperone binding;0.00121699182626205!GO:0005769;early endosome;0.00130169806829212!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.00132028518756952!GO:0046489;phosphoinositide biosynthetic process;0.00133566466818651!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00139131698699208!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00139131698699208!GO:0032508;DNA duplex unwinding;0.00139131698699208!GO:0032392;DNA geometric change;0.00139131698699208!GO:0000049;tRNA binding;0.00143560052803793!GO:0030119;AP-type membrane coat adaptor complex;0.0015337764158292!GO:0048500;signal recognition particle;0.00157186783053036!GO:0000287;magnesium ion binding;0.00170644134749079!GO:0007052;mitotic spindle organization and biogenesis;0.00177866601338692!GO:0016859;cis-trans isomerase activity;0.00182783492651106!GO:0030118;clathrin coat;0.00183617666839651!GO:0044431;Golgi apparatus part;0.00187934536431991!GO:0051252;regulation of RNA metabolic process;0.00193121294246831!GO:0009112;nucleobase metabolic process;0.0019621426286689!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0019621426286689!GO:0032561;guanyl ribonucleotide binding;0.00203945240325394!GO:0019001;guanyl nucleotide binding;0.00203945240325394!GO:0022890;inorganic cation transmembrane transporter activity;0.00204331717493935!GO:0003714;transcription corepressor activity;0.00206966094407344!GO:0046467;membrane lipid biosynthetic process;0.00207320699378367!GO:0007050;cell cycle arrest;0.00208122862081794!GO:0005048;signal sequence binding;0.00220494896722324!GO:0030521;androgen receptor signaling pathway;0.00238599017130084!GO:0015036;disulfide oxidoreductase activity;0.0025800220504938!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00258619071333055!GO:0008312;7S RNA binding;0.00260002493550782!GO:0006270;DNA replication initiation;0.00263232116709486!GO:0030131;clathrin adaptor complex;0.00264038325124558!GO:0004576;oligosaccharyl transferase activity;0.00264038325124558!GO:0042802;identical protein binding;0.00271110891729075!GO:0006268;DNA unwinding during replication;0.00272904432932185!GO:0008610;lipid biosynthetic process;0.00276052638223794!GO:0043065;positive regulation of apoptosis;0.00281091158857638!GO:0006611;protein export from nucleus;0.00284616833069218!GO:0009889;regulation of biosynthetic process;0.00285621841804629!GO:0047485;protein N-terminus binding;0.00291286070957946!GO:0030384;phosphoinositide metabolic process;0.00294481249809459!GO:0009967;positive regulation of signal transduction;0.00311087995009935!GO:0006338;chromatin remodeling;0.00312273223897581!GO:0031072;heat shock protein binding;0.00313242089225255!GO:0043068;positive regulation of programmed cell death;0.00332118174699392!GO:0035258;steroid hormone receptor binding;0.00334293410766676!GO:0004674;protein serine/threonine kinase activity;0.00340694155157628!GO:0051539;4 iron, 4 sulfur cluster binding;0.00348516062928315!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00349271756398133!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00351205717845966!GO:0045047;protein targeting to ER;0.00351205717845966!GO:0000922;spindle pole;0.00351205717845966!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00352560396969152!GO:0006595;polyamine metabolic process;0.00355054828162901!GO:0008047;enzyme activator activity;0.00358811853722164!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00369418047868254!GO:0006650;glycerophospholipid metabolic process;0.00378767524113602!GO:0003711;transcription elongation regulator activity;0.00399345234795727!GO:0032259;methylation;0.00402443191476871!GO:0032200;telomere organization and biogenesis;0.00413420883913223!GO:0000723;telomere maintenance;0.00413420883913223!GO:0031124;mRNA 3'-end processing;0.00414476827956457!GO:0043284;biopolymer biosynthetic process;0.00432878831332844!GO:0043488;regulation of mRNA stability;0.00436487878848729!GO:0043487;regulation of RNA stability;0.00436487878848729!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00436515694617413!GO:0030518;steroid hormone receptor signaling pathway;0.00437708052764886!GO:0005774;vacuolar membrane;0.00439805396180397!GO:0009116;nucleoside metabolic process;0.00440838541541065!GO:0008287;protein serine/threonine phosphatase complex;0.00465000031323031!GO:0032774;RNA biosynthetic process;0.00470833058732444!GO:0043414;biopolymer methylation;0.00474291942455364!GO:0008250;oligosaccharyl transferase complex;0.00476763144017248!GO:0006144;purine base metabolic process;0.00478970563901732!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0049945691121784!GO:0019843;rRNA binding;0.00505427153751465!GO:0005758;mitochondrial intermembrane space;0.00518648588300031!GO:0005791;rough endoplasmic reticulum;0.00534781998802448!GO:0006351;transcription, DNA-dependent;0.00554606725111034!GO:0030176;integral to endoplasmic reticulum membrane;0.00559354260293721!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00562937136657746!GO:0048522;positive regulation of cellular process;0.00572133595022538!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00585788911533207!GO:0000096;sulfur amino acid metabolic process;0.00594142243765806!GO:0004003;ATP-dependent DNA helicase activity;0.00597805507234229!GO:0000792;heterochromatin;0.00615791273506489!GO:0000178;exosome (RNase complex);0.00628053774187864!GO:0006284;base-excision repair;0.00644575126262959!GO:0051540;metal cluster binding;0.00650638792251408!GO:0051536;iron-sulfur cluster binding;0.00650638792251408!GO:0016272;prefoldin complex;0.00664237676325482!GO:0006275;regulation of DNA replication;0.00682766444146997!GO:0003725;double-stranded RNA binding;0.00711899630619872!GO:0042393;histone binding;0.00723531173028901!GO:0006807;nitrogen compound metabolic process;0.0073597628428098!GO:0003677;DNA binding;0.00746408633238111!GO:0004177;aminopeptidase activity;0.0075845703083842!GO:0008276;protein methyltransferase activity;0.0075845703083842!GO:0008408;3'-5' exonuclease activity;0.00759313268323731!GO:0000339;RNA cap binding;0.00759313268323731!GO:0009451;RNA modification;0.00759313268323731!GO:0033116;ER-Golgi intermediate compartment membrane;0.00777772303016899!GO:0006917;induction of apoptosis;0.0080081593152831!GO:0005669;transcription factor TFIID complex;0.00835279014571417!GO:0015631;tubulin binding;0.00884531024976142!GO:0004532;exoribonuclease activity;0.00884676191475677!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00884676191475677!GO:0048487;beta-tubulin binding;0.00897644544088529!GO:0009308;amine metabolic process;0.00927536094066099!GO:0006740;NADPH regeneration;0.00935211449196847!GO:0006098;pentose-phosphate shunt;0.00935211449196847!GO:0009303;rRNA transcription;0.00935211449196847!GO:0006730;one-carbon compound metabolic process;0.00935211449196847!GO:0009124;nucleoside monophosphate biosynthetic process;0.00935211449196847!GO:0009123;nucleoside monophosphate metabolic process;0.00935211449196847!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00935211449196847!GO:0015002;heme-copper terminal oxidase activity;0.00935211449196847!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00935211449196847!GO:0004129;cytochrome-c oxidase activity;0.00935211449196847!GO:0031252;leading edge;0.00935211449196847!GO:0043022;ribosome binding;0.00939310115248878!GO:0007242;intracellular signaling cascade;0.00940647590413452!GO:0006220;pyrimidine nucleotide metabolic process;0.00944168000962942!GO:0006289;nucleotide-excision repair;0.00948469269768907!GO:0016311;dephosphorylation;0.00965224775962542!GO:0006891;intra-Golgi vesicle-mediated transport;0.00974142080024793!GO:0050662;coenzyme binding;0.00975737702483026!GO:0030522;intracellular receptor-mediated signaling pathway;0.00982190753582145!GO:0009081;branched chain family amino acid metabolic process;0.00994466045917197!GO:0044437;vacuolar part;0.0099855405874638!GO:0050790;regulation of catalytic activity;0.0101178849387916!GO:0006509;membrane protein ectodomain proteolysis;0.0101530716961327!GO:0033619;membrane protein proteolysis;0.0101530716961327!GO:0005832;chaperonin-containing T-complex;0.0101832558826476!GO:0012502;induction of programmed cell death;0.0102207984265606!GO:0004722;protein serine/threonine phosphatase activity;0.010429531313297!GO:0022415;viral reproductive process;0.0106981131577345!GO:0030041;actin filament polymerization;0.0107200654608716!GO:0031970;organelle envelope lumen;0.0108978648302215!GO:0005765;lysosomal membrane;0.0110319153611242!GO:0006506;GPI anchor biosynthetic process;0.01120208468705!GO:0030663;COPI coated vesicle membrane;0.0116416585344817!GO:0030126;COPI vesicle coat;0.0116416585344817!GO:0046128;purine ribonucleoside metabolic process;0.0116692532735492!GO:0042278;purine nucleoside metabolic process;0.0116692532735492!GO:0031123;RNA 3'-end processing;0.0117390989316888!GO:0045892;negative regulation of transcription, DNA-dependent;0.0117614412156371!GO:0007264;small GTPase mediated signal transduction;0.0118984788575815!GO:0006378;mRNA polyadenylation;0.0119200852187689!GO:0008139;nuclear localization sequence binding;0.0121279452070271!GO:0032984;macromolecular complex disassembly;0.0124118746548644!GO:0018196;peptidyl-asparagine modification;0.0125831247963872!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0125831247963872!GO:0005876;spindle microtubule;0.0128052276049754!GO:0051287;NAD binding;0.0130839093887056!GO:0051789;response to protein stimulus;0.0131624655498269!GO:0006986;response to unfolded protein;0.0131624655498269!GO:0003756;protein disulfide isomerase activity;0.0133250808496145!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0133250808496145!GO:0000139;Golgi membrane;0.0133424649753084!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0134133979073111!GO:0045045;secretory pathway;0.0136785246719286!GO:0016584;nucleosome positioning;0.0137098332152557!GO:0007040;lysosome organization and biogenesis;0.0139745910282583!GO:0008637;apoptotic mitochondrial changes;0.0140250730314851!GO:0030145;manganese ion binding;0.0140361266015218!GO:0046983;protein dimerization activity;0.0140361266015218!GO:0016407;acetyltransferase activity;0.0140542439290249!GO:0007021;tubulin folding;0.0142071624258565!GO:0006695;cholesterol biosynthetic process;0.0142343151274304!GO:0030658;transport vesicle membrane;0.0142684407096629!GO:0043189;H4/H2A histone acetyltransferase complex;0.0144587454329204!GO:0035267;NuA4 histone acetyltransferase complex;0.0147172262466182!GO:0046822;regulation of nucleocytoplasmic transport;0.0148668094458756!GO:0030134;ER to Golgi transport vesicle;0.0149056989786822!GO:0022411;cellular component disassembly;0.0152785596027887!GO:0006497;protein amino acid lipidation;0.0152951467256802!GO:0006672;ceramide metabolic process;0.0155283802203564!GO:0006376;mRNA splice site selection;0.0156375013866472!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0156375013866472!GO:0006607;NLS-bearing substrate import into nucleus;0.0156375013866472!GO:0018193;peptidyl-amino acid modification;0.0157867342285811!GO:0016126;sterol biosynthetic process;0.0158925317691816!GO:0006505;GPI anchor metabolic process;0.016052520259322!GO:0016044;membrane organization and biogenesis;0.0161563282313167!GO:0046966;thyroid hormone receptor binding;0.0161563282313167!GO:0031570;DNA integrity checkpoint;0.016193337967322!GO:0032039;integrator complex;0.0162450899556096!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0171227858745208!GO:0046112;nucleobase biosynthetic process;0.0175480594114576!GO:0003746;translation elongation factor activity;0.0176073744924053!GO:0016860;intramolecular oxidoreductase activity;0.0176341460944804!GO:0000725;recombinational repair;0.0178435391270234!GO:0000724;double-strand break repair via homologous recombination;0.0178435391270234!GO:0048471;perinuclear region of cytoplasm;0.0180606720613352!GO:0009161;ribonucleoside monophosphate metabolic process;0.018296679367368!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.018296679367368!GO:0033673;negative regulation of kinase activity;0.018363566410284!GO:0006469;negative regulation of protein kinase activity;0.018363566410284!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0186644793273034!GO:0016605;PML body;0.0186868674009856!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0187208396209912!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0187266267087687!GO:0019318;hexose metabolic process;0.0188471699903044!GO:0000726;non-recombinational repair;0.0190695621355938!GO:0005996;monosaccharide metabolic process;0.0194589357622071!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.0196617877873704!GO:0000123;histone acetyltransferase complex;0.0197219760836792!GO:0051348;negative regulation of transferase activity;0.0199601470037872!GO:0005869;dynactin complex;0.0199601470037872!GO:0006007;glucose catabolic process;0.0201224062080697!GO:0048037;cofactor binding;0.0203871611703993!GO:0000118;histone deacetylase complex;0.0204476226941859!GO:0043241;protein complex disassembly;0.0205521319724201!GO:0045449;regulation of transcription;0.0209472640512919!GO:0006979;response to oxidative stress;0.0209919670936565!GO:0040029;regulation of gene expression, epigenetic;0.0210822800548675!GO:0016408;C-acyltransferase activity;0.0211152735395754!GO:0030137;COPI-coated vesicle;0.0212223316748023!GO:0043596;nuclear replication fork;0.0216232085553536!GO:0030127;COPII vesicle coat;0.0216620236428732!GO:0012507;ER to Golgi transport vesicle membrane;0.0216620236428732!GO:0006733;oxidoreduction coenzyme metabolic process;0.0222318271486464!GO:0008320;protein transmembrane transporter activity;0.0228822970374709!GO:0007033;vacuole organization and biogenesis;0.0229090135818778!GO:0000097;sulfur amino acid biosynthetic process;0.0229726759695233!GO:0050178;phenylpyruvate tautomerase activity;0.0233424277474174!GO:0051053;negative regulation of DNA metabolic process;0.0239279306641288!GO:0007017;microtubule-based process;0.0239279306641288!GO:0008213;protein amino acid alkylation;0.0239279306641288!GO:0006479;protein amino acid methylation;0.0239279306641288!GO:0008180;signalosome;0.0239678847598914!GO:0016791;phosphoric monoester hydrolase activity;0.0239678847598914!GO:0008629;induction of apoptosis by intracellular signals;0.0241655115391267!GO:0006118;electron transport;0.0241655115391267!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.024502056181453!GO:0000819;sister chromatid segregation;0.0245276132487245!GO:0003887;DNA-directed DNA polymerase activity;0.0245681324407854!GO:0030660;Golgi-associated vesicle membrane;0.0246187601054837!GO:0060090;molecular adaptor activity;0.0247000237488433!GO:0007004;telomere maintenance via telomerase;0.0248407240452752!GO:0046426;negative regulation of JAK-STAT cascade;0.025300380695465!GO:0042770;DNA damage response, signal transduction;0.0256632530000409!GO:0000228;nuclear chromosome;0.0263321267814303!GO:0030132;clathrin coat of coated pit;0.0266334534079184!GO:0003702;RNA polymerase II transcription factor activity;0.0272252219072072!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0281767047092446!GO:0008538;proteasome activator activity;0.0282607797202686!GO:0000781;chromosome, telomeric region;0.0284176893276937!GO:0006596;polyamine biosynthetic process;0.0284837224024051!GO:0009083;branched chain family amino acid catabolic process;0.028498350804659!GO:0000152;nuclear ubiquitin ligase complex;0.0287529873909893!GO:0005744;mitochondrial inner membrane presequence translocase complex;0.0287762031441748!GO:0031371;ubiquitin conjugating enzyme complex;0.0287974871286359!GO:0005874;microtubule;0.0287974871286359!GO:0005652;nuclear lamina;0.0287974871286359!GO:0046365;monosaccharide catabolic process;0.0287974871286359!GO:0043624;cellular protein complex disassembly;0.0287974871286359!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.0287974871286359!GO:0033367;protein localization in mast cell secretory granule;0.0287974871286359!GO:0033365;protein localization in organelle;0.0287974871286359!GO:0033371;T cell secretory granule organization and biogenesis;0.0287974871286359!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.0287974871286359!GO:0033375;protease localization in T cell secretory granule;0.0287974871286359!GO:0042629;mast cell granule;0.0287974871286359!GO:0033377;maintenance of protein localization in T cell secretory granule;0.0287974871286359!GO:0033364;mast cell secretory granule organization and biogenesis;0.0287974871286359!GO:0033380;granzyme B localization in T cell secretory granule;0.0287974871286359!GO:0033379;maintenance of protease localization in T cell secretory granule;0.0287974871286359!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.0287974871286359!GO:0033368;protease localization in mast cell secretory granule;0.0287974871286359!GO:0033366;protein localization in secretory granule;0.0287974871286359!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.0287974871286359!GO:0033374;protein localization in T cell secretory granule;0.0287974871286359!GO:0016197;endosome transport;0.0288403471528156!GO:0007259;JAK-STAT cascade;0.0292113061448291!GO:0000070;mitotic sister chromatid segregation;0.0294410500601618!GO:0030984;kininogen binding;0.029602274045713!GO:0004213;cathepsin B activity;0.029602274045713!GO:0005096;GTPase activator activity;0.0308389971080286!GO:0031577;spindle checkpoint;0.0308389971080286!GO:0030508;thiol-disulfide exchange intermediate activity;0.0311713508388292!GO:0030433;ER-associated protein catabolic process;0.0314132215047252!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0314132215047252!GO:0019206;nucleoside kinase activity;0.0318128944467744!GO:0051235;maintenance of localization;0.0319803922190294!GO:0005784;translocon complex;0.0329219341445335!GO:0004540;ribonuclease activity;0.033027939849336!GO:0008415;acyltransferase activity;0.0331655376016396!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0332125431298432!GO:0000175;3'-5'-exoribonuclease activity;0.0340975083870369!GO:0008017;microtubule binding;0.0340985197610843!GO:0008170;N-methyltransferase activity;0.0341006818829131!GO:0006360;transcription from RNA polymerase I promoter;0.034815304479153!GO:0048518;positive regulation of biological process;0.0351088212569524!GO:0042158;lipoprotein biosynthetic process;0.0353012854867889!GO:0000910;cytokinesis;0.0353944385677027!GO:0050681;androgen receptor binding;0.0354439282306949!GO:0008652;amino acid biosynthetic process;0.0356759277071435!GO:0006470;protein amino acid dephosphorylation;0.0356862325367894!GO:0016747;transferase activity, transferring groups other than amino-acyl groups;0.0359498653125431!GO:0032940;secretion by cell;0.0371001106874148!GO:0006400;tRNA modification;0.0374506977236002!GO:0000159;protein phosphatase type 2A complex;0.0377423398349758!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0378538748009088!GO:0000077;DNA damage checkpoint;0.0379448152988031!GO:0005092;GDP-dissociation inhibitor activity;0.0380051333854095!GO:0004748;ribonucleoside-diphosphate reductase activity;0.038192918346347!GO:0016728;oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor;0.038192918346347!GO:0009119;ribonucleoside metabolic process;0.0382073052520511!GO:0032981;mitochondrial respiratory chain complex I assembly;0.038221058531576!GO:0010257;NADH dehydrogenase complex assembly;0.038221058531576!GO:0033108;mitochondrial respiratory chain complex assembly;0.038221058531576!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.038524722139712!GO:0045039;protein import into mitochondrial inner membrane;0.038524722139712!GO:0045947;negative regulation of translational initiation;0.0391594658907577!GO:0031625;ubiquitin protein ligase binding;0.0400714937729635!GO:0051098;regulation of binding;0.0402820129472354!GO:0008097;5S rRNA binding;0.0404455273233554!GO:0006779;porphyrin biosynthetic process;0.0409009366625756!GO:0033014;tetrapyrrole biosynthetic process;0.0409009366625756!GO:0006739;NADP metabolic process;0.0409009366625756!GO:0031902;late endosome membrane;0.0412546611059789!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0413867112406514!GO:0006278;RNA-dependent DNA replication;0.0415182645451101!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0419564369701388!GO:0009396;folic acid and derivative biosynthetic process;0.0419564369701388!GO:0030911;TPR domain binding;0.0422467208846066!GO:0016180;snRNA processing;0.0422467208846066!GO:0016073;snRNA metabolic process;0.0422467208846066!GO:0016746;transferase activity, transferring acyl groups;0.0422467208846066!GO:0046164;alcohol catabolic process;0.0423486865290664!GO:0008022;protein C-terminus binding;0.0427951070501542!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.0429054921654427!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.0430658856398586!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.0430658856398586!GO:0009126;purine nucleoside monophosphate metabolic process;0.0430658856398586!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.0430658856398586!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0433103927296646!GO:0022884;macromolecule transmembrane transporter activity;0.0433984393540855!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0433984393540855!GO:0030133;transport vesicle;0.0433984393540855!GO:0019320;hexose catabolic process;0.0435222842591067!GO:0042532;negative regulation of tyrosine phosphorylation of STAT protein;0.0437138703389199!GO:0042518;negative regulation of tyrosine phosphorylation of Stat3 protein;0.0437138703389199!GO:0050732;negative regulation of peptidyl-tyrosine phosphorylation;0.0437138703389199!GO:0006892;post-Golgi vesicle-mediated transport;0.0443764983482544!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0450983639731865!GO:0008601;protein phosphatase type 2A regulator activity;0.045181881685186!GO:0032507;maintenance of cellular protein localization;0.0452186331078588!GO:0015923;mannosidase activity;0.0465179349775416!GO:0000303;response to superoxide;0.0467542566814674!GO:0008536;Ran GTPase binding;0.0471756975013153!GO:0000790;nuclear chromatin;0.0472170153770386!GO:0045815;positive regulation of gene expression, epigenetic;0.0472289120299338!GO:0005975;carbohydrate metabolic process;0.0474857348597004!GO:0008361;regulation of cell size;0.0475490525155757!GO:0000209;protein polyubiquitination;0.0484919724867038!GO:0005666;DNA-directed RNA polymerase III complex;0.0486500882611047!GO:0004448;isocitrate dehydrogenase activity;0.0488153829003689!GO:0046588;negative regulation of calcium-dependent cell-cell adhesion;0.0493257054221554!GO:0046586;regulation of calcium-dependent cell-cell adhesion;0.0493257054221554!GO:0008624;induction of apoptosis by extracellular signals;0.0497175656806267!GO:0006406;mRNA export from nucleus;0.0498686484874706 | |||
|sample_id=10801 | |sample_id=10801 | ||
|sample_note= | |sample_note= | ||
Line 76: | Line 99: | ||
|sample_tissue=blood | |sample_tissue=blood | ||
|top_motifs=RXR{A,B,G}_{NR1H2,PPAR}dimers:1.82251741506;ALX1:1.60046636006;MYB:1.51014496864;GATA6:1.43803514315;POU3F1..4:1.28503625799;RUNX1..3:1.213120772;E2F1..5:1.21270208545;ELF1,2,4:1.16621426064;FOX{I1,J2}:1.15370540865;ZBTB16:1.12347628545;NANOG{mouse}:0.9711915973;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.966690243268;NR5A1,2:0.89284687112;YY1:0.863561841387;PITX1..3:0.860690574659;DMAP1_NCOR{1,2}_SMARC:0.850816457601;POU2F1..3:0.816732653207;SPIB:0.77378353677;TEF:0.734746148279;AIRE:0.722730542083;HES1:0.721295822781;ZNF143:0.698637444873;ETS1,2:0.615351258622;HIF1A:0.592431969204;AR:0.570063825336;SPI1:0.563996537351;NFY{A,B,C}:0.543808010815;FOXP1:0.538830977117;NKX3-1:0.536056065364;IKZF2:0.530129460393;ELK1,4_GABP{A,B1}:0.522952470666;CUX2:0.453742475924;bHLH_family:0.43367396961;CREB1:0.400400532791;FOXD3:0.397752213684;BREu{core}:0.391219678878;NKX2-1,4:0.376380344731;CDX1,2,4:0.371909629664;TOPORS:0.334131636326;PRRX1,2:0.332742614445;POU1F1:0.330770842885;PAX6:0.323813378461;NRF1:0.32318119253;FOXQ1:0.277955507292;STAT1,3:0.277833929788;GCM1,2:0.26778530128;SOX17:0.257731071984;NKX2-3_NKX2-5:0.255499404095;PBX1:0.25201174212;PPARG:0.245287436818;FOXP3:0.228221739608;STAT5{A,B}:0.220984368216;GATA4:0.172592864189;PAX2:0.141444977409;PAX8:0.137724851541;DBP:0.12018232416;NKX2-2,8:0.0919340980318;NFIL3:0.0902555244316;FOXN1:0.0895532984825;ARID5B:0.0816344714589;HAND1,2:0.0603174581204;ONECUT1,2:0.0462368444714;HOXA9_MEIS1:0.0382713105365;MYOD1:0.0337364461919;SOX{8,9,10}:0.0101509197323;CRX:-0.00391005044479;HOX{A4,D4}:-0.022012680457;PAX3,7:-0.0427272595286;NFE2L1:-0.0598213806858;ATF5_CREB3:-0.0615839026237;RORA:-0.0803613540933;HBP1_HMGB_SSRP1_UBTF:-0.0908567417381;HNF1A:-0.0997422439477;PDX1:-0.101734363276;TFAP4:-0.103722224939;HNF4A_NR2F1,2:-0.106563930207;AHR_ARNT_ARNT2:-0.110251915713;NFATC1..3:-0.121807631722;EVI1:-0.131043571233;ZNF384:-0.138701070062;VSX1,2:-0.140139691502;RBPJ:-0.152868927786;RFX2..5_RFXANK_RFXAP:-0.157059223126;NFE2L2:-0.159671516247;EP300:-0.160159258928;NR6A1:-0.172371084788;POU6F1:-0.177303477776;ESRRA:-0.181618864913;RXR{A,B,G}:-0.182677756012;ZIC1..3:-0.187397279154;REST:-0.189613781293;ZNF423:-0.202408318313;PAX1,9:-0.20291396558;MEF2{A,B,C,D}:-0.204399140993;STAT2,4,6:-0.215907128487;XBP1:-0.221466436297;TFDP1:-0.226765638858;HIC1:-0.230755132874;EN1,2:-0.235537151711;OCT4_SOX2{dimer}:-0.239204558564;LHX3,4:-0.245197704973;FOXA2:-0.252041569267;NFE2:-0.261906367665;NKX6-1,2:-0.272474057484;NANOG:-0.278122872767;TLX2:-0.288280215231;LEF1_TCF7_TCF7L1,2:-0.306300598808;ZNF238:-0.307954507353;ZNF148:-0.324099356463;PRDM1:-0.334894264269;FOX{F1,F2,J1}:-0.342571104643;BACH2:-0.347379075933;CEBPA,B_DDIT3:-0.351479246087;NFKB1_REL_RELA:-0.35782869466;ZFP161:-0.386486896318;PAX5:-0.397311326406;MYBL2:-0.397645094876;FOS_FOS{B,L1}_JUN{B,D}:-0.413240179849;HOX{A5,B5}:-0.432326807757;SNAI1..3:-0.454131774082;RREB1:-0.454909435578;SRF:-0.48264364189;SOX2:-0.49245714354;IRF1,2:-0.515505873305;UFEwm:-0.516729819273;ESR1:-0.522356656917;ATF4:-0.530387331267;KLF4:-0.532666472161;ZEB1:-0.535864704517;PAX4:-0.554237778102;POU5F1:-0.564997746952;MTF1:-0.574423640037;HLF:-0.602330331494;TGIF1:-0.611049812653;FOSL2:-0.617941820386;TAL1_TCF{3,4,12}:-0.62457168657;NHLH1,2:-0.628158392045;RXRA_VDR{dimer}:-0.633356090203;EGR1..3:-0.636845038752;SOX5:-0.638218159445;MZF1:-0.645810159016;TBP:-0.655876705993;GTF2A1,2:-0.660220663225;EBF1:-0.664419812861;TFAP2B:-0.671757277043;FOXM1:-0.690317886884;MYFfamily:-0.692204577524;SMAD1..7,9:-0.701281053061;IKZF1:-0.702550177049;HOX{A6,A7,B6,B7}:-0.707840175875;ZBTB6:-0.716885654245;ALX4:-0.72618240043;GLI1..3:-0.729999151786;GTF2I:-0.734200933851;BPTF:-0.736894653883;RFX1:-0.753023977136;SREBF1,2:-0.767400270442;GFI1:-0.770944631481;ATF6:-0.79910706202;XCPE1{core}:-0.818890445892;FOXL1:-0.819384273494;HMGA1,2:-0.819854195907;CDC5L:-0.825588256869;IRF7:-0.842641904338;GZF1:-0.84465591674;NKX3-2:-0.851717157953;PATZ1:-0.913572050871;MED-1{core}:-0.933091844688;SP1:-0.933177078332;TFAP2{A,C}:-0.934960090768;TEAD1:-0.940771069636;FOXO1,3,4:-0.993288645396;HMX1:-0.99676301474;HSF1,2:-1.01557322137;T:-1.01820601853;MAZ:-1.03692846654;FOX{D1,D2}:-1.05657447464;TP53:-1.07590686961;MTE{core}:-1.08449087795;TLX1..3_NFIC{dimer}:-1.10982025127;JUN:-1.13761981831;SPZ1:-1.18209274696;LMO2:-1.22103563472;ATF2:-1.26064109372;ADNP_IRX_SIX_ZHX:-1.44259635166;TBX4,5:-1.4993766992;NFIX:-1.52252587581;GFI1B:-1.64015411173;MAFB:-1.65717290087;NR3C1:-1.67203595255;TFCP2:-1.68455065825;NR1H4:-1.72050204635 | |top_motifs=RXR{A,B,G}_{NR1H2,PPAR}dimers:1.82251741506;ALX1:1.60046636006;MYB:1.51014496864;GATA6:1.43803514315;POU3F1..4:1.28503625799;RUNX1..3:1.213120772;E2F1..5:1.21270208545;ELF1,2,4:1.16621426064;FOX{I1,J2}:1.15370540865;ZBTB16:1.12347628545;NANOG{mouse}:0.9711915973;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.966690243268;NR5A1,2:0.89284687112;YY1:0.863561841387;PITX1..3:0.860690574659;DMAP1_NCOR{1,2}_SMARC:0.850816457601;POU2F1..3:0.816732653207;SPIB:0.77378353677;TEF:0.734746148279;AIRE:0.722730542083;HES1:0.721295822781;ZNF143:0.698637444873;ETS1,2:0.615351258622;HIF1A:0.592431969204;AR:0.570063825336;SPI1:0.563996537351;NFY{A,B,C}:0.543808010815;FOXP1:0.538830977117;NKX3-1:0.536056065364;IKZF2:0.530129460393;ELK1,4_GABP{A,B1}:0.522952470666;CUX2:0.453742475924;bHLH_family:0.43367396961;CREB1:0.400400532791;FOXD3:0.397752213684;BREu{core}:0.391219678878;NKX2-1,4:0.376380344731;CDX1,2,4:0.371909629664;TOPORS:0.334131636326;PRRX1,2:0.332742614445;POU1F1:0.330770842885;PAX6:0.323813378461;NRF1:0.32318119253;FOXQ1:0.277955507292;STAT1,3:0.277833929788;GCM1,2:0.26778530128;SOX17:0.257731071984;NKX2-3_NKX2-5:0.255499404095;PBX1:0.25201174212;PPARG:0.245287436818;FOXP3:0.228221739608;STAT5{A,B}:0.220984368216;GATA4:0.172592864189;PAX2:0.141444977409;PAX8:0.137724851541;DBP:0.12018232416;NKX2-2,8:0.0919340980318;NFIL3:0.0902555244316;FOXN1:0.0895532984825;ARID5B:0.0816344714589;HAND1,2:0.0603174581204;ONECUT1,2:0.0462368444714;HOXA9_MEIS1:0.0382713105365;MYOD1:0.0337364461919;SOX{8,9,10}:0.0101509197323;CRX:-0.00391005044479;HOX{A4,D4}:-0.022012680457;PAX3,7:-0.0427272595286;NFE2L1:-0.0598213806858;ATF5_CREB3:-0.0615839026237;RORA:-0.0803613540933;HBP1_HMGB_SSRP1_UBTF:-0.0908567417381;HNF1A:-0.0997422439477;PDX1:-0.101734363276;TFAP4:-0.103722224939;HNF4A_NR2F1,2:-0.106563930207;AHR_ARNT_ARNT2:-0.110251915713;NFATC1..3:-0.121807631722;EVI1:-0.131043571233;ZNF384:-0.138701070062;VSX1,2:-0.140139691502;RBPJ:-0.152868927786;RFX2..5_RFXANK_RFXAP:-0.157059223126;NFE2L2:-0.159671516247;EP300:-0.160159258928;NR6A1:-0.172371084788;POU6F1:-0.177303477776;ESRRA:-0.181618864913;RXR{A,B,G}:-0.182677756012;ZIC1..3:-0.187397279154;REST:-0.189613781293;ZNF423:-0.202408318313;PAX1,9:-0.20291396558;MEF2{A,B,C,D}:-0.204399140993;STAT2,4,6:-0.215907128487;XBP1:-0.221466436297;TFDP1:-0.226765638858;HIC1:-0.230755132874;EN1,2:-0.235537151711;OCT4_SOX2{dimer}:-0.239204558564;LHX3,4:-0.245197704973;FOXA2:-0.252041569267;NFE2:-0.261906367665;NKX6-1,2:-0.272474057484;NANOG:-0.278122872767;TLX2:-0.288280215231;LEF1_TCF7_TCF7L1,2:-0.306300598808;ZNF238:-0.307954507353;ZNF148:-0.324099356463;PRDM1:-0.334894264269;FOX{F1,F2,J1}:-0.342571104643;BACH2:-0.347379075933;CEBPA,B_DDIT3:-0.351479246087;NFKB1_REL_RELA:-0.35782869466;ZFP161:-0.386486896318;PAX5:-0.397311326406;MYBL2:-0.397645094876;FOS_FOS{B,L1}_JUN{B,D}:-0.413240179849;HOX{A5,B5}:-0.432326807757;SNAI1..3:-0.454131774082;RREB1:-0.454909435578;SRF:-0.48264364189;SOX2:-0.49245714354;IRF1,2:-0.515505873305;UFEwm:-0.516729819273;ESR1:-0.522356656917;ATF4:-0.530387331267;KLF4:-0.532666472161;ZEB1:-0.535864704517;PAX4:-0.554237778102;POU5F1:-0.564997746952;MTF1:-0.574423640037;HLF:-0.602330331494;TGIF1:-0.611049812653;FOSL2:-0.617941820386;TAL1_TCF{3,4,12}:-0.62457168657;NHLH1,2:-0.628158392045;RXRA_VDR{dimer}:-0.633356090203;EGR1..3:-0.636845038752;SOX5:-0.638218159445;MZF1:-0.645810159016;TBP:-0.655876705993;GTF2A1,2:-0.660220663225;EBF1:-0.664419812861;TFAP2B:-0.671757277043;FOXM1:-0.690317886884;MYFfamily:-0.692204577524;SMAD1..7,9:-0.701281053061;IKZF1:-0.702550177049;HOX{A6,A7,B6,B7}:-0.707840175875;ZBTB6:-0.716885654245;ALX4:-0.72618240043;GLI1..3:-0.729999151786;GTF2I:-0.734200933851;BPTF:-0.736894653883;RFX1:-0.753023977136;SREBF1,2:-0.767400270442;GFI1:-0.770944631481;ATF6:-0.79910706202;XCPE1{core}:-0.818890445892;FOXL1:-0.819384273494;HMGA1,2:-0.819854195907;CDC5L:-0.825588256869;IRF7:-0.842641904338;GZF1:-0.84465591674;NKX3-2:-0.851717157953;PATZ1:-0.913572050871;MED-1{core}:-0.933091844688;SP1:-0.933177078332;TFAP2{A,C}:-0.934960090768;TEAD1:-0.940771069636;FOXO1,3,4:-0.993288645396;HMX1:-0.99676301474;HSF1,2:-1.01557322137;T:-1.01820601853;MAZ:-1.03692846654;FOX{D1,D2}:-1.05657447464;TP53:-1.07590686961;MTE{core}:-1.08449087795;TLX1..3_NFIC{dimer}:-1.10982025127;JUN:-1.13761981831;SPZ1:-1.18209274696;LMO2:-1.22103563472;ATF2:-1.26064109372;ADNP_IRX_SIX_ZHX:-1.44259635166;TBX4,5:-1.4993766992;NFIX:-1.52252587581;GFI1B:-1.64015411173;MAFB:-1.65717290087;NR3C1:-1.67203595255;TFCP2:-1.68455065825;NR1H4:-1.72050204635 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10801-110I9;search_select_hide=table117:FF:10801-110I9 | |||
}} | }} |
Latest revision as of 15:05, 3 June 2020
Name: | chronic myeloblastic leukemia (CML) cell line:KCL-22 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11886 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11886
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11886
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.14 |
10 | 10 | 0.00648 |
100 | 100 | 0.58 |
101 | 101 | 0.737 |
102 | 102 | 0.404 |
103 | 103 | 0.83 |
104 | 104 | 0.804 |
105 | 105 | 0.966 |
106 | 106 | 0.68 |
107 | 107 | 0.837 |
108 | 108 | 0.501 |
109 | 109 | 0.0793 |
11 | 11 | 0.0515 |
110 | 110 | 0.118 |
111 | 111 | 0.0802 |
112 | 112 | 0.586 |
113 | 113 | 0.987 |
114 | 114 | 0.0376 |
115 | 115 | 0.807 |
116 | 116 | 0.197 |
117 | 117 | 0.0133 |
118 | 118 | 0.0319 |
119 | 119 | 0.897 |
12 | 12 | 0.886 |
120 | 120 | 0.274 |
121 | 121 | 0.833 |
122 | 122 | 0.843 |
123 | 123 | 0.00771 |
124 | 124 | 0.466 |
125 | 125 | 0.24 |
126 | 126 | 0.493 |
127 | 127 | 0.0801 |
128 | 128 | 0.465 |
129 | 129 | 0.695 |
13 | 13 | 0.00211 |
130 | 130 | 0.795 |
131 | 131 | 0.389 |
132 | 132 | 0.622 |
133 | 133 | 0.622 |
134 | 134 | 0.917 |
135 | 135 | 0.596 |
136 | 136 | 0.204 |
137 | 137 | 0.459 |
138 | 138 | 0.279 |
139 | 139 | 0.978 |
14 | 14 | 0.891 |
140 | 140 | 0.333 |
141 | 141 | 0.114 |
142 | 142 | 0.482 |
143 | 143 | 0.212 |
144 | 144 | 0.295 |
145 | 145 | 0.206 |
146 | 146 | 0.623 |
147 | 147 | 0.00872 |
148 | 148 | 0.0601 |
149 | 149 | 0.221 |
15 | 15 | 0.255 |
150 | 150 | 0.705 |
151 | 151 | 0.79 |
152 | 152 | 0.663 |
153 | 153 | 0.595 |
154 | 154 | 0.892 |
155 | 155 | 0.0387 |
156 | 156 | 0.27 |
157 | 157 | 0.167 |
158 | 158 | 0.869 |
159 | 159 | 0.364 |
16 | 16 | 0.397 |
160 | 160 | 0.386 |
161 | 161 | 0.18 |
162 | 162 | 0.455 |
163 | 163 | 0.999 |
164 | 164 | 0.111 |
165 | 165 | 0.527 |
166 | 166 | 0.0499 |
167 | 167 | 0.173 |
168 | 168 | 0.107 |
169 | 169 | 0.0307 |
17 | 17 | 0.858 |
18 | 18 | 0.206 |
19 | 19 | 0.923 |
2 | 2 | 0.568 |
20 | 20 | 0.218 |
21 | 21 | 0.302 |
22 | 22 | 0.387 |
23 | 23 | 0.0428 |
24 | 24 | 0.184 |
25 | 25 | 0.144 |
26 | 26 | 0.0237 |
27 | 27 | 0.816 |
28 | 28 | 0.853 |
29 | 29 | 0.12 |
3 | 3 | 0.144 |
30 | 30 | 0.1 |
31 | 31 | 0.187 |
32 | 32 | 0.00978 |
33 | 33 | 0.502 |
34 | 34 | 0.749 |
35 | 35 | 0.659 |
36 | 36 | 0.0653 |
37 | 37 | 0.251 |
38 | 38 | 0.41 |
39 | 39 | 0.212 |
4 | 4 | 0.284 |
40 | 40 | 0.347 |
41 | 41 | 0.86 |
42 | 42 | 0.259 |
43 | 43 | 0.607 |
44 | 44 | 0.0218 |
45 | 45 | 0.42 |
46 | 46 | 0.0739 |
47 | 47 | 0.0299 |
48 | 48 | 0.00765 |
49 | 49 | 0.249 |
5 | 5 | 0.757 |
50 | 50 | 0.955 |
51 | 51 | 0.655 |
52 | 52 | 0.0973 |
53 | 53 | 0.123 |
54 | 54 | 0.975 |
55 | 55 | 0.109 |
56 | 56 | 0.95 |
57 | 57 | 0.035 |
58 | 58 | 0.13 |
59 | 59 | 0.469 |
6 | 6 | 0.333 |
60 | 60 | 0.777 |
61 | 61 | 0.0437 |
62 | 62 | 0.158 |
63 | 63 | 0.554 |
64 | 64 | 0.136 |
65 | 65 | 0.761 |
66 | 66 | 0.0533 |
67 | 67 | 0.471 |
68 | 68 | 0.908 |
69 | 69 | 0.871 |
7 | 7 | 0.0395 |
70 | 70 | 0.882 |
71 | 71 | 0.0317 |
72 | 72 | 0.683 |
73 | 73 | 0.179 |
74 | 74 | 0.654 |
75 | 75 | 0.0101 |
76 | 76 | 0.0648 |
77 | 77 | 0.844 |
78 | 78 | 0.0722 |
79 | 79 | 0.393 |
8 | 8 | 0.0556 |
80 | 80 | 0.0787 |
81 | 81 | 0.646 |
82 | 82 | 0.981 |
83 | 83 | 0.398 |
84 | 84 | 0.339 |
85 | 85 | 0.232 |
86 | 86 | 0.783 |
87 | 87 | 0.127 |
88 | 88 | 0.446 |
89 | 89 | 0.625 |
9 | 9 | 0.749 |
90 | 90 | 0.496 |
91 | 91 | 0.666 |
92 | 92 | 0.281 |
93 | 93 | 0.438 |
94 | 94 | 0.935 |
95 | 95 | 0.00306 |
96 | 96 | 0.367 |
97 | 97 | 0.281 |
98 | 98 | 0.219 |
99 | 99 | 0.557 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11886
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0104137 KCL-22 cell sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
1240 (leukemia)
1036 (chronic leukemia)
8692 (myeloid leukemia)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100737 (leukemia cell line sample)
0102580 (chronic myeloid leukemia cell line sample)
0101035 (hematopoietic cell line sample)
0100740 (myeloid leukemia cell line sample)
0104137 (KCL-22 cell sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)