FF:11563-120D6: Difference between revisions
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|library_id=CNhs12566 | |library_id=CNhs12566 | ||
|library_id_phase_based=2:CNhs12566 | |library_id_phase_based=2:CNhs12566 | ||
|name= | |name=Mast cell, donor1 | ||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |profile_cagescan=,,, | ||
|profile_hcage= | |profile_hcage=CNhs12566,LSID917,release011,COMPLETED | ||
|profile_rnaseq= | |profile_rnaseq= | ||
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| ||
Line 80: | Line 80: | ||
|sample_donor(cell lot)= | |sample_donor(cell lot)= | ||
|sample_ethnicity= | |sample_ethnicity= | ||
|sample_experimental_condition= | |sample_experimental_condition=control, untreated cells | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.13341167518645e-241!GO:0043227;membrane-bound organelle;4.56928324722982e-212!GO:0043231;intracellular membrane-bound organelle;1.00045611131882e-211!GO:0043226;organelle;9.05988299731312e-199!GO:0043229;intracellular organelle;5.98182219676545e-198!GO:0005737;cytoplasm;4.48047147765162e-160!GO:0044422;organelle part;1.37572552015942e-132!GO:0044446;intracellular organelle part;1.14078180706058e-130!GO:0044444;cytoplasmic part;4.1594544311172e-120!GO:0044237;cellular metabolic process;3.1357824615295e-101!GO:0044238;primary metabolic process;5.68825778123729e-101!GO:0005634;nucleus;2.99045222968547e-97!GO:0043170;macromolecule metabolic process;1.02231884591549e-96!GO:0032991;macromolecular complex;1.3072569805929e-88!GO:0044428;nuclear part;8.13210341546878e-72!GO:0030529;ribonucleoprotein complex;1.84922452780146e-71!GO:0003723;RNA binding;2.36699142978696e-68!GO:0043283;biopolymer metabolic process;5.3556380225131e-65!GO:0043233;organelle lumen;3.61300495316985e-63!GO:0031974;membrane-enclosed lumen;3.61300495316985e-63!GO:0005515;protein binding;4.91413754461186e-58!GO:0005739;mitochondrion;2.62464291384688e-54!GO:0010467;gene expression;1.6992679192567e-51!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.77557151661901e-51!GO:0033036;macromolecule localization;2.54748937911238e-51!GO:0015031;protein transport;8.47155235670493e-50!GO:0019538;protein metabolic process;7.71239433167514e-48!GO:0045184;establishment of protein localization;1.14054044931772e-47!GO:0031090;organelle membrane;3.1575882404913e-47!GO:0008104;protein localization;5.59153962553871e-47!GO:0043234;protein complex;1.13564422546642e-45!GO:0006396;RNA processing;4.81511148346588e-44!GO:0044267;cellular protein metabolic process;5.26462609669783e-44!GO:0044260;cellular macromolecule metabolic process;2.94763720900311e-43!GO:0016071;mRNA metabolic process;4.11145548097117e-43!GO:0031981;nuclear lumen;2.62941953158245e-42!GO:0006412;translation;1.82229426077747e-41!GO:0016043;cellular component organization and biogenesis;1.29037887685214e-38!GO:0005840;ribosome;5.29834622700185e-38!GO:0044429;mitochondrial part;4.77247161355003e-37!GO:0005829;cytosol;6.80271355018651e-37!GO:0003676;nucleic acid binding;1.97654585037718e-36!GO:0006397;mRNA processing;2.93536954564391e-36!GO:0008380;RNA splicing;4.73122493022645e-36!GO:0031967;organelle envelope;1.15269921161479e-35!GO:0031975;envelope;2.64605404656882e-35!GO:0046907;intracellular transport;4.54356714938749e-35!GO:0009058;biosynthetic process;7.38151387985147e-34!GO:0009059;macromolecule biosynthetic process;1.07398861911019e-33!GO:0065003;macromolecular complex assembly;1.72853064845847e-32!GO:0006259;DNA metabolic process;1.8849210554014e-32!GO:0003735;structural constituent of ribosome;1.8849210554014e-32!GO:0006996;organelle organization and biogenesis;1.73708713668428e-31!GO:0044249;cellular biosynthetic process;1.91146224434498e-31!GO:0006886;intracellular protein transport;2.75604668824074e-31!GO:0033279;ribosomal subunit;7.24377960593275e-29!GO:0022607;cellular component assembly;1.10545161301785e-28!GO:0000166;nucleotide binding;4.93637092175171e-28!GO:0051649;establishment of cellular localization;6.54080948218014e-28!GO:0005654;nucleoplasm;8.77288245315253e-28!GO:0016070;RNA metabolic process;3.89783368878639e-27!GO:0051641;cellular localization;4.04860750873572e-27!GO:0005681;spliceosome;2.73064894875988e-26!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.38889573746487e-25!GO:0005740;mitochondrial envelope;7.52535329274508e-25!GO:0019866;organelle inner membrane;2.51216768641593e-24!GO:0031966;mitochondrial membrane;2.40963140455617e-23!GO:0005830;cytosolic ribosome (sensu Eukaryota);4.0230695522341e-23!GO:0007049;cell cycle;1.89651565905499e-22!GO:0044445;cytosolic part;2.332637294909e-22!GO:0005743;mitochondrial inner membrane;4.51131436855103e-22!GO:0044451;nucleoplasm part;6.76160726200255e-22!GO:0043228;non-membrane-bound organelle;1.06369682271479e-21!GO:0043232;intracellular non-membrane-bound organelle;1.06369682271479e-21!GO:0006119;oxidative phosphorylation;1.42219928627804e-21!GO:0006512;ubiquitin cycle;8.01514893300957e-21!GO:0012505;endomembrane system;2.06406080267237e-20!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;4.07284057986593e-20!GO:0016462;pyrophosphatase activity;4.3043415288283e-20!GO:0016817;hydrolase activity, acting on acid anhydrides;4.79361223396297e-20!GO:0032553;ribonucleotide binding;8.23409248086856e-20!GO:0032555;purine ribonucleotide binding;8.23409248086856e-20!GO:0043412;biopolymer modification;1.35023562312488e-19!GO:0017111;nucleoside-triphosphatase activity;2.47166782321599e-19!GO:0017076;purine nucleotide binding;4.59889604180289e-19!GO:0051276;chromosome organization and biogenesis;4.63599100580885e-19!GO:0044455;mitochondrial membrane part;1.49835937980467e-18!GO:0044265;cellular macromolecule catabolic process;2.30448064911472e-18!GO:0006974;response to DNA damage stimulus;3.48172830296276e-18!GO:0016874;ligase activity;3.65366664140109e-18!GO:0005694;chromosome;8.63562661985255e-18!GO:0022618;protein-RNA complex assembly;1.01222005579957e-17!GO:0008134;transcription factor binding;1.58729217707738e-17!GO:0006464;protein modification process;1.81342791755564e-17!GO:0022402;cell cycle process;2.4157102683304e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;2.4763940415798e-17!GO:0019941;modification-dependent protein catabolic process;3.59692791531615e-17!GO:0043632;modification-dependent macromolecule catabolic process;3.59692791531615e-17!GO:0044257;cellular protein catabolic process;4.24763521201393e-17!GO:0005524;ATP binding;4.82574458831686e-17!GO:0006511;ubiquitin-dependent protein catabolic process;5.59282749833154e-17!GO:0048770;pigment granule;1.08159592441718e-16!GO:0042470;melanosome;1.08159592441718e-16!GO:0006325;establishment and/or maintenance of chromatin architecture;1.08344037687465e-16!GO:0032559;adenyl ribonucleotide binding;1.74550221061067e-16!GO:0006323;DNA packaging;6.98051511503371e-16!GO:0043687;post-translational protein modification;8.23134095872227e-16!GO:0044427;chromosomal part;1.37815892861711e-15!GO:0043285;biopolymer catabolic process;1.41193795595103e-15!GO:0030554;adenyl nucleotide binding;1.41193795595103e-15!GO:0005746;mitochondrial respiratory chain;1.45682259930287e-15!GO:0044248;cellular catabolic process;2.54581321980941e-15!GO:0016604;nuclear body;4.3222046544299e-15!GO:0015935;small ribosomal subunit;4.74733296927817e-15!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;4.9626950283905e-15!GO:0000502;proteasome complex (sensu Eukaryota);5.44231401977285e-15!GO:0016192;vesicle-mediated transport;5.61577058454513e-15!GO:0006281;DNA repair;6.4823336063637e-15!GO:0005794;Golgi apparatus;8.2591061221116e-15!GO:0031980;mitochondrial lumen;1.48345771757626e-14!GO:0005759;mitochondrial matrix;1.48345771757626e-14!GO:0015934;large ribosomal subunit;1.59320868540655e-14!GO:0005730;nucleolus;1.8098435883599e-14!GO:0005783;endoplasmic reticulum;2.04096443438253e-14!GO:0009057;macromolecule catabolic process;2.19950114455076e-14!GO:0012501;programmed cell death;2.65360660636723e-14!GO:0006915;apoptosis;3.39971970522115e-14!GO:0008135;translation factor activity, nucleic acid binding;4.38337520734807e-14!GO:0050136;NADH dehydrogenase (quinone) activity;4.64425802645631e-14!GO:0003954;NADH dehydrogenase activity;4.64425802645631e-14!GO:0008137;NADH dehydrogenase (ubiquinone) activity;4.64425802645631e-14!GO:0006457;protein folding;5.40458852604409e-14!GO:0000278;mitotic cell cycle;8.4428647179876e-14!GO:0050794;regulation of cellular process;8.55664418640362e-14!GO:0008219;cell death;1.75851240415503e-13!GO:0016265;death;1.75851240415503e-13!GO:0065004;protein-DNA complex assembly;2.02670965434004e-13!GO:0006333;chromatin assembly or disassembly;3.26757099647205e-13!GO:0030163;protein catabolic process;3.37579656067067e-13!GO:0006605;protein targeting;6.70707314279396e-13!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.0333573821695e-12!GO:0051186;cofactor metabolic process;1.20212813477499e-12!GO:0042775;organelle ATP synthesis coupled electron transport;1.2819709330047e-12!GO:0042773;ATP synthesis coupled electron transport;1.2819709330047e-12!GO:0000398;nuclear mRNA splicing, via spliceosome;1.84697007265161e-12!GO:0000375;RNA splicing, via transesterification reactions;1.84697007265161e-12!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.84697007265161e-12!GO:0048193;Golgi vesicle transport;2.47997934180523e-12!GO:0016607;nuclear speck;2.47997934180523e-12!GO:0016887;ATPase activity;2.50048793296043e-12!GO:0044432;endoplasmic reticulum part;2.80764029406397e-12!GO:0030964;NADH dehydrogenase complex (quinone);3.59257946077462e-12!GO:0045271;respiratory chain complex I;3.59257946077462e-12!GO:0005747;mitochondrial respiratory chain complex I;3.59257946077462e-12!GO:0042623;ATPase activity, coupled;4.89850894598581e-12!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);6.99108605015947e-12!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;7.95412713999009e-12!GO:0006793;phosphorus metabolic process;8.0002321835133e-12!GO:0006796;phosphate metabolic process;8.0002321835133e-12!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);8.39586888038234e-12!GO:0022403;cell cycle phase;1.26278961254794e-11!GO:0003712;transcription cofactor activity;1.31146687458999e-11!GO:0005635;nuclear envelope;1.96915739487903e-11!GO:0006413;translational initiation;2.5646360213524e-11!GO:0003743;translation initiation factor activity;2.72083063467416e-11!GO:0006446;regulation of translational initiation;6.55976994371794e-11!GO:0009719;response to endogenous stimulus;7.31014835168353e-11!GO:0051726;regulation of cell cycle;1.14020723904367e-10!GO:0019222;regulation of metabolic process;1.36626772960837e-10!GO:0006732;coenzyme metabolic process;1.37049648522054e-10!GO:0000074;regulation of progression through cell cycle;1.37293994301221e-10!GO:0008639;small protein conjugating enzyme activity;1.55719377017083e-10!GO:0000785;chromatin;1.60826944749783e-10!GO:0044453;nuclear membrane part;1.93130210297214e-10!GO:0016568;chromatin modification;2.18173909728261e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;2.54321590523381e-10!GO:0000087;M phase of mitotic cell cycle;3.21115198322815e-10!GO:0051082;unfolded protein binding;3.63713812968552e-10!GO:0051301;cell division;3.69177394073292e-10!GO:0031965;nuclear membrane;3.69177394073292e-10!GO:0042175;nuclear envelope-endoplasmic reticulum network;3.73987218661443e-10!GO:0016310;phosphorylation;4.12365595331675e-10!GO:0004842;ubiquitin-protein ligase activity;4.48653683692588e-10!GO:0006913;nucleocytoplasmic transport;5.99396119637833e-10!GO:0019787;small conjugating protein ligase activity;6.18328075577187e-10!GO:0007067;mitosis;6.33969471280948e-10!GO:0004386;helicase activity;6.62753946139476e-10!GO:0005789;endoplasmic reticulum membrane;7.17275216195115e-10!GO:0051169;nuclear transport;1.02972814516913e-09!GO:0050657;nucleic acid transport;1.05534332572086e-09!GO:0051236;establishment of RNA localization;1.05534332572086e-09!GO:0050658;RNA transport;1.05534332572086e-09!GO:0006334;nucleosome assembly;1.11265326803201e-09!GO:0005768;endosome;1.18070554588418e-09!GO:0006403;RNA localization;2.03751710940623e-09!GO:0005761;mitochondrial ribosome;2.45646632834147e-09!GO:0000313;organellar ribosome;2.45646632834147e-09!GO:0031497;chromatin assembly;2.55446881844528e-09!GO:0019829;cation-transporting ATPase activity;2.99348610855452e-09!GO:0008565;protein transporter activity;3.43946381912005e-09!GO:0042254;ribosome biogenesis and assembly;3.6038602971967e-09!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;4.42578449107427e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;5.10631616624313e-09!GO:0000279;M phase;5.92984769289952e-09!GO:0050789;regulation of biological process;6.21467927402517e-09!GO:0006260;DNA replication;8.51834553439268e-09!GO:0005773;vacuole;9.78849899956812e-09!GO:0006366;transcription from RNA polymerase II promoter;1.13412744530246e-08!GO:0016881;acid-amino acid ligase activity;1.13765729828391e-08!GO:0005793;ER-Golgi intermediate compartment;1.15228675954882e-08!GO:0009056;catabolic process;1.21035579653436e-08!GO:0008026;ATP-dependent helicase activity;1.25887408368562e-08!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.64210845925507e-08!GO:0016740;transferase activity;1.87166901727618e-08!GO:0031323;regulation of cellular metabolic process;2.22826871351327e-08!GO:0048523;negative regulation of cellular process;2.22826871351327e-08!GO:0015986;ATP synthesis coupled proton transport;2.22826871351327e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;2.22826871351327e-08!GO:0042981;regulation of apoptosis;2.33720271280151e-08!GO:0043067;regulation of programmed cell death;3.19737472123334e-08!GO:0015078;hydrogen ion transmembrane transporter activity;3.36327275698172e-08!GO:0005643;nuclear pore;3.72617498970516e-08!GO:0051028;mRNA transport;5.46806707757434e-08!GO:0043566;structure-specific DNA binding;5.71364491493333e-08!GO:0006163;purine nucleotide metabolic process;5.72425546075097e-08!GO:0065002;intracellular protein transport across a membrane;5.85439053913672e-08!GO:0003697;single-stranded DNA binding;6.19103184251189e-08!GO:0051246;regulation of protein metabolic process;6.35658503524449e-08!GO:0016787;hydrolase activity;7.26335481850097e-08!GO:0016772;transferase activity, transferring phosphorus-containing groups;8.23530124238852e-08!GO:0006164;purine nucleotide biosynthetic process;1.22722431663712e-07!GO:0003713;transcription coactivator activity;1.24172639825832e-07!GO:0009055;electron carrier activity;1.2740940849262e-07!GO:0006888;ER to Golgi vesicle-mediated transport;1.27428350100753e-07!GO:0031982;vesicle;1.55543682810988e-07!GO:0009060;aerobic respiration;1.68128867915627e-07!GO:0009259;ribonucleotide metabolic process;1.97614579137871e-07!GO:0006350;transcription;2.18887219946914e-07!GO:0000323;lytic vacuole;2.18887219946914e-07!GO:0005764;lysosome;2.18887219946914e-07!GO:0009150;purine ribonucleotide metabolic process;2.26038502076634e-07!GO:0051188;cofactor biosynthetic process;2.40043849218412e-07!GO:0048519;negative regulation of biological process;2.77472683079271e-07!GO:0006754;ATP biosynthetic process;2.94281010519283e-07!GO:0006753;nucleoside phosphate metabolic process;2.94281010519283e-07!GO:0044431;Golgi apparatus part;3.11464975896608e-07!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;3.32455218615129e-07!GO:0016469;proton-transporting two-sector ATPase complex;3.37053056374442e-07!GO:0031988;membrane-bound vesicle;3.38930412447712e-07!GO:0046930;pore complex;3.45765210680856e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;3.6829131950765e-07!GO:0009144;purine nucleoside triphosphate metabolic process;3.6829131950765e-07!GO:0046034;ATP metabolic process;3.9062737501884e-07!GO:0010468;regulation of gene expression;3.9062737501884e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;4.13531164364818e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;4.13531164364818e-07!GO:0005839;proteasome core complex (sensu Eukaryota);4.31097373063655e-07!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;4.43562230545365e-07!GO:0009152;purine ribonucleotide biosynthetic process;4.60876099115342e-07!GO:0006461;protein complex assembly;5.41637872045406e-07!GO:0009199;ribonucleoside triphosphate metabolic process;5.67448679167275e-07!GO:0045333;cellular respiration;5.70268724841096e-07!GO:0017038;protein import;5.87815583123943e-07!GO:0009141;nucleoside triphosphate metabolic process;6.29643515758126e-07!GO:0009142;nucleoside triphosphate biosynthetic process;6.91225804657069e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;6.91225804657069e-07!GO:0030532;small nuclear ribonucleoprotein complex;7.43234210341849e-07!GO:0015630;microtubule cytoskeleton;7.8106926026282e-07!GO:0031410;cytoplasmic vesicle;8.30457545845363e-07!GO:0009260;ribonucleotide biosynthetic process;9.73414899274104e-07!GO:0016023;cytoplasmic membrane-bound vesicle;1.18399132546886e-06!GO:0045786;negative regulation of progression through cell cycle;1.2000469092862e-06!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;1.34722421105237e-06!GO:0006364;rRNA processing;1.38814389029527e-06!GO:0007243;protein kinase cascade;1.47244312628907e-06!GO:0030120;vesicle coat;1.50810217351291e-06!GO:0030662;coated vesicle membrane;1.50810217351291e-06!GO:0032446;protein modification by small protein conjugation;1.54789984489291e-06!GO:0048475;coated membrane;1.58594035534995e-06!GO:0030117;membrane coat;1.58594035534995e-06!GO:0007249;I-kappaB kinase/NF-kappaB cascade;1.58601089100251e-06!GO:0043069;negative regulation of programmed cell death;1.81712270351666e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;1.90793460074872e-06!GO:0000245;spliceosome assembly;1.91492250018325e-06!GO:0007242;intracellular signaling cascade;1.93318008243764e-06!GO:0016072;rRNA metabolic process;2.08736237030535e-06!GO:0043066;negative regulation of apoptosis;2.22635196760564e-06!GO:0004298;threonine endopeptidase activity;2.47594188714354e-06!GO:0006916;anti-apoptosis;2.83370137175489e-06!GO:0016567;protein ubiquitination;3.08618596565399e-06!GO:0006099;tricarboxylic acid cycle;3.3482877391073e-06!GO:0046356;acetyl-CoA catabolic process;3.3482877391073e-06!GO:0009108;coenzyme biosynthetic process;3.4758045369982e-06!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;3.53012731417865e-06!GO:0004812;aminoacyl-tRNA ligase activity;3.53012731417865e-06!GO:0016875;ligase activity, forming carbon-oxygen bonds;3.53012731417865e-06!GO:0016779;nucleotidyltransferase activity;3.73005289198881e-06!GO:0006399;tRNA metabolic process;3.83819110293798e-06!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.96490076441272e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;4.2011721738952e-06!GO:0008270;zinc ion binding;4.43202120582311e-06!GO:0005813;centrosome;4.56737934213854e-06!GO:0019899;enzyme binding;5.07950998601382e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;5.09617734825977e-06!GO:0045259;proton-transporting ATP synthase complex;5.17960455135483e-06!GO:0016563;transcription activator activity;5.86080181608394e-06!GO:0044440;endosomal part;5.86942908494946e-06!GO:0010008;endosome membrane;5.86942908494946e-06!GO:0007264;small GTPase mediated signal transduction;6.02472098510376e-06!GO:0043038;amino acid activation;6.4045416185473e-06!GO:0006418;tRNA aminoacylation for protein translation;6.4045416185473e-06!GO:0043039;tRNA aminoacylation;6.4045416185473e-06!GO:0008654;phospholipid biosynthetic process;6.61025776500103e-06!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;6.90038627440163e-06!GO:0006084;acetyl-CoA metabolic process;6.98202757750801e-06!GO:0006613;cotranslational protein targeting to membrane;7.54780561817556e-06!GO:0005770;late endosome;7.8955084682394e-06!GO:0000151;ubiquitin ligase complex;8.71721527637131e-06!GO:0003724;RNA helicase activity;9.62535841793726e-06!GO:0005525;GTP binding;1.01323959303878e-05!GO:0003924;GTPase activity;1.16972851985578e-05!GO:0006752;group transfer coenzyme metabolic process;1.1710510001351e-05!GO:0030384;phosphoinositide metabolic process;1.27739076390756e-05!GO:0005815;microtubule organizing center;1.32393353365094e-05!GO:0007005;mitochondrion organization and biogenesis;1.57672044033631e-05!GO:0032774;RNA biosynthetic process;1.57672044033631e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;1.58189132035469e-05!GO:0015399;primary active transmembrane transporter activity;1.58189132035469e-05!GO:0006818;hydrogen transport;1.69326409600814e-05!GO:0065007;biological regulation;1.84652723571773e-05!GO:0000786;nucleosome;1.88145324818012e-05!GO:0006351;transcription, DNA-dependent;1.884650006554e-05!GO:0015992;proton transport;1.98736687265444e-05!GO:0004674;protein serine/threonine kinase activity;2.49404986604968e-05!GO:0016197;endosome transport;2.61979378049818e-05!GO:0006402;mRNA catabolic process;2.62930901555892e-05!GO:0005798;Golgi-associated vesicle;2.78875636212949e-05!GO:0051187;cofactor catabolic process;2.85287383099196e-05!GO:0065009;regulation of a molecular function;3.0171265383517e-05!GO:0006612;protein targeting to membrane;3.15781622974164e-05!GO:0000139;Golgi membrane;3.2697964183375e-05!GO:0009109;coenzyme catabolic process;3.82471299985123e-05!GO:0006650;glycerophospholipid metabolic process;4.37416019113392e-05!GO:0046914;transition metal ion binding;4.64260098178894e-05!GO:0009117;nucleotide metabolic process;5.20971468061775e-05!GO:0051168;nuclear export;5.39045913850069e-05!GO:0016363;nuclear matrix;5.58020298723726e-05!GO:0045449;regulation of transcription;5.76430068135006e-05!GO:0045045;secretory pathway;5.90070643167821e-05!GO:0051170;nuclear import;6.03734356188912e-05!GO:0005769;early endosome;6.16884130106031e-05!GO:0032561;guanyl ribonucleotide binding;8.21737493546103e-05!GO:0019001;guanyl nucleotide binding;8.21737493546103e-05!GO:0016251;general RNA polymerase II transcription factor activity;8.97632411035918e-05!GO:0005819;spindle;9.99496984478481e-05!GO:0006606;protein import into nucleus;0.000119554686947565!GO:0051329;interphase of mitotic cell cycle;0.000123654205722878!GO:0003677;DNA binding;0.000124044396243072!GO:0003729;mRNA binding;0.000128551389949037!GO:0006261;DNA-dependent DNA replication;0.000163819990190528!GO:0032940;secretion by cell;0.000197444366374513!GO:0003690;double-stranded DNA binding;0.000213447518277506!GO:0005885;Arp2/3 protein complex;0.000214252699245926!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00021726114170699!GO:0051325;interphase;0.000221177856800872!GO:0043492;ATPase activity, coupled to movement of substances;0.000228139747106355!GO:0008186;RNA-dependent ATPase activity;0.000232966282565559!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000234891698042114!GO:0016564;transcription repressor activity;0.000265108752440878!GO:0006352;transcription initiation;0.00026603004062057!GO:0051427;hormone receptor binding;0.000277111846014891!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000279277528171885!GO:0043623;cellular protein complex assembly;0.000280390159023305!GO:0008610;lipid biosynthetic process;0.000285847665925913!GO:0031252;leading edge;0.000295875651127106!GO:0031324;negative regulation of cellular metabolic process;0.000303838422327421!GO:0046467;membrane lipid biosynthetic process;0.000308011729461057!GO:0030695;GTPase regulator activity;0.000316436265764033!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000327089648918999!GO:0006891;intra-Golgi vesicle-mediated transport;0.000405746821475403!GO:0051789;response to protein stimulus;0.000411087930464354!GO:0006986;response to unfolded protein;0.000411087930464354!GO:0043021;ribonucleoprotein binding;0.000427485765182785!GO:0006643;membrane lipid metabolic process;0.000438157875565994!GO:0006401;RNA catabolic process;0.000446189682776207!GO:0022890;inorganic cation transmembrane transporter activity;0.000497708080499824!GO:0006355;regulation of transcription, DNA-dependent;0.000503781893357574!GO:0035257;nuclear hormone receptor binding;0.000514466872835994!GO:0005774;vacuolar membrane;0.000556085219601202!GO:0016491;oxidoreductase activity;0.000627561304768647!GO:0048471;perinuclear region of cytoplasm;0.000633416345592959!GO:0006302;double-strand break repair;0.000637038946473515!GO:0000775;chromosome, pericentric region;0.000649039993237567!GO:0004004;ATP-dependent RNA helicase activity;0.000689064163401767!GO:0006091;generation of precursor metabolites and energy;0.000708721299458157!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000720112676036993!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000798130756474472!GO:0003899;DNA-directed RNA polymerase activity;0.000805219915162832!GO:0030521;androgen receptor signaling pathway;0.0008231137834033!GO:0008047;enzyme activator activity;0.000830659480101205!GO:0009892;negative regulation of metabolic process;0.000843952829094831!GO:0003714;transcription corepressor activity;0.000843952829094831!GO:0046489;phosphoinositide biosynthetic process;0.000855870715840656!GO:0009967;positive regulation of signal transduction;0.000863813392344443!GO:0006417;regulation of translation;0.000980828590128432!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000992820599644323!GO:0030518;steroid hormone receptor signaling pathway;0.000998075911010113!GO:0046474;glycerophospholipid biosynthetic process;0.00102072097807741!GO:0050790;regulation of catalytic activity;0.00104039963283334!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00109786406978269!GO:0016301;kinase activity;0.00115883344706366!GO:0006310;DNA recombination;0.00116507189338614!GO:0045454;cell redox homeostasis;0.00137567588729363!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0014198262196576!GO:0007050;cell cycle arrest;0.00144064311952711!GO:0031968;organelle outer membrane;0.00144771795354756!GO:0000075;cell cycle checkpoint;0.00148758485265466!GO:0005096;GTPase activator activity;0.00150708738184509!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00154691359171728!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00154691359171728!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00154691359171728!GO:0005667;transcription factor complex;0.00155635416125639!GO:0048500;signal recognition particle;0.00161108124832028!GO:0044437;vacuolar part;0.00162319294464047!GO:0030659;cytoplasmic vesicle membrane;0.00162918494140095!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.00164971379759806!GO:0019867;outer membrane;0.0016637772326478!GO:0019372;lipoxygenase pathway;0.00169656743026342!GO:0051252;regulation of RNA metabolic process;0.00175174116872372!GO:0000287;magnesium ion binding;0.00184234454960089!GO:0004428;inositol or phosphatidylinositol kinase activity;0.00185437440910116!GO:0022406;membrane docking;0.00192202430568419!GO:0048278;vesicle docking;0.00192202430568419!GO:0030658;transport vesicle membrane;0.0019574998104444!GO:0012506;vesicle membrane;0.00197945734601876!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.00210051784532483!GO:0033116;ER-Golgi intermediate compartment membrane;0.00217266157057225!GO:0007040;lysosome organization and biogenesis;0.00218112074450126!GO:0031072;heat shock protein binding;0.00222431927246198!GO:0006383;transcription from RNA polymerase III promoter;0.00225721404214783!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00237757243272214!GO:0030522;intracellular receptor-mediated signaling pathway;0.00243345784611903!GO:0006414;translational elongation;0.00248723657542275!GO:0048522;positive regulation of cellular process;0.00249284311432602!GO:0005741;mitochondrial outer membrane;0.00249284311432602!GO:0015980;energy derivation by oxidation of organic compounds;0.00259380251570056!GO:0005637;nuclear inner membrane;0.00260060253924821!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00269398329496227!GO:0043681;protein import into mitochondrion;0.00270255013084733!GO:0006904;vesicle docking during exocytosis;0.0030299616921288!GO:0003684;damaged DNA binding;0.003105653455877!GO:0016481;negative regulation of transcription;0.00312609559498433!GO:0031326;regulation of cellular biosynthetic process;0.00319213244557008!GO:0007034;vacuolar transport;0.00322404539504916!GO:0004527;exonuclease activity;0.00322404539504916!GO:0000776;kinetochore;0.00325220195463127!GO:0006405;RNA export from nucleus;0.00328439904536222!GO:0005762;mitochondrial large ribosomal subunit;0.00330418045817961!GO:0000315;organellar large ribosomal subunit;0.00330418045817961!GO:0005657;replication fork;0.00334233684621981!GO:0006644;phospholipid metabolic process;0.00335584212501669!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00338285097169525!GO:0045047;protein targeting to ER;0.00338285097169525!GO:0005048;signal sequence binding;0.00340175778149852!GO:0046519;sphingoid metabolic process;0.00341658940924648!GO:0030660;Golgi-associated vesicle membrane;0.00354473238052184!GO:0007033;vacuole organization and biogenesis;0.00357182328003398!GO:0006672;ceramide metabolic process;0.00357258322772911!GO:0015631;tubulin binding;0.00358950641982834!GO:0033673;negative regulation of kinase activity;0.00366049206544712!GO:0006469;negative regulation of protein kinase activity;0.00366049206544712!GO:0005788;endoplasmic reticulum lumen;0.00368750426321514!GO:0008287;protein serine/threonine phosphatase complex;0.00386797781810485!GO:0006917;induction of apoptosis;0.00388427071989824!GO:0005765;lysosomal membrane;0.00390038026693719!GO:0030127;COPII vesicle coat;0.00391088711145028!GO:0012507;ER to Golgi transport vesicle membrane;0.00391088711145028!GO:0007265;Ras protein signal transduction;0.00393216011000589!GO:0007059;chromosome segregation;0.00406056039057829!GO:0044433;cytoplasmic vesicle part;0.00418532540775082!GO:0030663;COPI coated vesicle membrane;0.00419847796633063!GO:0030126;COPI vesicle coat;0.00419847796633063!GO:0051920;peroxiredoxin activity;0.00420027933949302!GO:0007051;spindle organization and biogenesis;0.00422126249631753!GO:0031902;late endosome membrane;0.00425158140890606!GO:0030176;integral to endoplasmic reticulum membrane;0.0042649670342286!GO:0000314;organellar small ribosomal subunit;0.00432774894393102!GO:0005763;mitochondrial small ribosomal subunit;0.00432774894393102!GO:0043488;regulation of mRNA stability;0.00434051715035263!GO:0043487;regulation of RNA stability;0.00434051715035263!GO:0009165;nucleotide biosynthetic process;0.004372523762137!GO:0008234;cysteine-type peptidase activity;0.004372523762137!GO:0004261;cathepsin G activity;0.00439565197840978!GO:0005083;small GTPase regulator activity;0.00443523270982456!GO:0051348;negative regulation of transferase activity;0.00448074699120444!GO:0047485;protein N-terminus binding;0.00461406922866255!GO:0030134;ER to Golgi transport vesicle;0.00467927529031358!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00475893822138616!GO:0012502;induction of programmed cell death;0.005125091212946!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00542450425726241!GO:0001726;ruffle;0.0056007776216907!GO:0033367;protein localization in mast cell secretory granule;0.0056007776216907!GO:0033365;protein localization in organelle;0.0056007776216907!GO:0033371;T cell secretory granule organization and biogenesis;0.0056007776216907!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.0056007776216907!GO:0033375;protease localization in T cell secretory granule;0.0056007776216907!GO:0042629;mast cell granule;0.0056007776216907!GO:0033377;maintenance of protein localization in T cell secretory granule;0.0056007776216907!GO:0033364;mast cell secretory granule organization and biogenesis;0.0056007776216907!GO:0033380;granzyme B localization in T cell secretory granule;0.0056007776216907!GO:0033379;maintenance of protease localization in T cell secretory granule;0.0056007776216907!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.0056007776216907!GO:0033368;protease localization in mast cell secretory granule;0.0056007776216907!GO:0033366;protein localization in secretory granule;0.0056007776216907!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.0056007776216907!GO:0033374;protein localization in T cell secretory granule;0.0056007776216907!GO:0016853;isomerase activity;0.0056007776216907!GO:0043065;positive regulation of apoptosis;0.00565016672354852!GO:0008312;7S RNA binding;0.00578583136436408!GO:0000082;G1/S transition of mitotic cell cycle;0.00582401724151927!GO:0030137;COPI-coated vesicle;0.00605583308587757!GO:0030880;RNA polymerase complex;0.00606041101789095!GO:0030867;rough endoplasmic reticulum membrane;0.00616422737650305!GO:0009889;regulation of biosynthetic process;0.00616422737650305!GO:0035258;steroid hormone receptor binding;0.00631691069271279!GO:0048487;beta-tubulin binding;0.00658842736145723!GO:0003711;transcription elongation regulator activity;0.00663223635991583!GO:0016126;sterol biosynthetic process;0.00667724089806075!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00669777677718107!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00682004136383109!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00682004136383109!GO:0043068;positive regulation of programmed cell death;0.00703442083512525!GO:0007088;regulation of mitosis;0.00709454193258185!GO:0008629;induction of apoptosis by intracellular signals;0.00710585717894053!GO:0000209;protein polyubiquitination;0.00737650935147595!GO:0008017;microtubule binding;0.00740609243229215!GO:0046854;phosphoinositide phosphorylation;0.00741405784742151!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00741405784742151!GO:0016584;nucleosome positioning;0.00764431172407783!GO:0005874;microtubule;0.00777745774335912!GO:0006633;fatty acid biosynthetic process;0.00777745774335912!GO:0035035;histone acetyltransferase binding;0.00777745774335912!GO:0006611;protein export from nucleus;0.00777745774335912!GO:0003678;DNA helicase activity;0.00778441153880233!GO:0006607;NLS-bearing substrate import into nucleus;0.00793585008847898!GO:0000049;tRNA binding;0.00793585008847898!GO:0019752;carboxylic acid metabolic process;0.00821954582709403!GO:0005669;transcription factor TFIID complex;0.00835994299918876!GO:0030258;lipid modification;0.0084248206372565!GO:0030118;clathrin coat;0.0088764582627506!GO:0018193;peptidyl-amino acid modification;0.00896946821513304!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00896946821513304!GO:0000428;DNA-directed RNA polymerase complex;0.00896946821513304!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00920854614187698!GO:0046483;heterocycle metabolic process;0.00920854614187698!GO:0019843;rRNA binding;0.00933715036435975!GO:0006626;protein targeting to mitochondrion;0.00937849363181621!GO:0006839;mitochondrial transport;0.00949602580638359!GO:0019783;small conjugating protein-specific protease activity;0.00963093045655631!GO:0000096;sulfur amino acid metabolic process;0.00983165911553142!GO:0006289;nucleotide-excision repair;0.00996613588967455!GO:0004843;ubiquitin-specific protease activity;0.00999536725825964!GO:0006082;organic acid metabolic process;0.010028987754467!GO:0008094;DNA-dependent ATPase activity;0.0102015077698436!GO:0004518;nuclease activity;0.0106464464269282!GO:0007006;mitochondrial membrane organization and biogenesis;0.0106875974916226!GO:0005684;U2-dependent spliceosome;0.0109023989447931!GO:0044255;cellular lipid metabolic process;0.0109604285970322!GO:0016044;membrane organization and biogenesis;0.0110647698797653!GO:0006509;membrane protein ectodomain proteolysis;0.0111502652012367!GO:0033619;membrane protein proteolysis;0.0111502652012367!GO:0003682;chromatin binding;0.011717575375472!GO:0031901;early endosome membrane;0.0118637856310691!GO:0051539;4 iron, 4 sulfur cluster binding;0.0123349630967099!GO:0005020;stem cell factor receptor activity;0.0123349630967099!GO:0008139;nuclear localization sequence binding;0.0125208211568106!GO:0042802;identical protein binding;0.0132177455522573!GO:0009966;regulation of signal transduction;0.0132205258254867!GO:0006661;phosphatidylinositol biosynthetic process;0.0133350832110774!GO:0044452;nucleolar part;0.0135204108791664!GO:0046834;lipid phosphorylation;0.0137351771907065!GO:0006338;chromatin remodeling;0.0137943534945323!GO:0016407;acetyltransferase activity;0.0137943534945323!GO:0006695;cholesterol biosynthetic process;0.0138118928975629!GO:0051540;metal cluster binding;0.0139642036129534!GO:0051536;iron-sulfur cluster binding;0.0139642036129534!GO:0051287;NAD binding;0.0139642036129534!GO:0044262;cellular carbohydrate metabolic process;0.0141169209203305!GO:0030036;actin cytoskeleton organization and biogenesis;0.0142973475725857!GO:0015036;disulfide oxidoreductase activity;0.0143183041188416!GO:0006376;mRNA splice site selection;0.0144278434481627!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0144278434481627!GO:0005869;dynactin complex;0.0144695359782645!GO:0060090;molecular adaptor activity;0.0145489956585992!GO:0032984;macromolecular complex disassembly;0.014828305281149!GO:0046488;phosphatidylinositol metabolic process;0.0148922012916433!GO:0022415;viral reproductive process;0.0151575116611951!GO:0016408;C-acyltransferase activity;0.015160146456011!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0152617547972827!GO:0016311;dephosphorylation;0.0152875084327769!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0153434957386898!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.0153434957386898!GO:0045576;mast cell activation;0.0157220775342618!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0161313912432114!GO:0030119;AP-type membrane coat adaptor complex;0.0161845896233492!GO:0005942;phosphoinositide 3-kinase complex;0.0161849547783796!GO:0006497;protein amino acid lipidation;0.0162465934828633!GO:0004221;ubiquitin thiolesterase activity;0.0169392234012927!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.0170110225484844!GO:0000059;protein import into nucleus, docking;0.0171345110465352!GO:0016790;thiolester hydrolase activity;0.0171378231862907!GO:0007052;mitotic spindle organization and biogenesis;0.0171446484509508!GO:0006740;NADPH regeneration;0.0173951835686915!GO:0006098;pentose-phosphate shunt;0.0173951835686915!GO:0004177;aminopeptidase activity;0.0175940065333457!GO:0000228;nuclear chromosome;0.0178095460897987!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0178095460897987!GO:0015002;heme-copper terminal oxidase activity;0.0178095460897987!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0178095460897987!GO:0004129;cytochrome-c oxidase activity;0.0178095460897987!GO:0007030;Golgi organization and biogenesis;0.0179225778713611!GO:0009615;response to virus;0.0180135541860322!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0180135541860322!GO:0033033;negative regulation of myeloid cell apoptosis;0.0180135541860322!GO:0001803;regulation of type III hypersensitivity;0.0180135541860322!GO:0032733;positive regulation of interleukin-10 production;0.0180135541860322!GO:0033025;regulation of mast cell apoptosis;0.0180135541860322!GO:0001805;positive regulation of type III hypersensitivity;0.0180135541860322!GO:0033023;mast cell homeostasis;0.0180135541860322!GO:0002431;Fc receptor mediated stimulatory signaling pathway;0.0180135541860322!GO:0033032;regulation of myeloid cell apoptosis;0.0180135541860322!GO:0001802;type III hypersensitivity;0.0180135541860322!GO:0033028;myeloid cell apoptosis;0.0180135541860322!GO:0042590;antigen processing and presentation of exogenous peptide antigen via MHC class I;0.0180135541860322!GO:0033026;negative regulation of mast cell apoptosis;0.0180135541860322!GO:0033024;mast cell apoptosis;0.0180135541860322!GO:0004722;protein serine/threonine phosphatase activity;0.0180982770388606!GO:0046394;carboxylic acid biosynthetic process;0.0180982770388606!GO:0016053;organic acid biosynthetic process;0.0180982770388606!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0185289455994785!GO:0007093;mitotic cell cycle checkpoint;0.0187854892004836!GO:0031124;mRNA 3'-end processing;0.018960403003045!GO:0004576;oligosaccharyl transferase activity;0.0189665136342473!GO:0000118;histone deacetylase complex;0.0191282585355141!GO:0015923;mannosidase activity;0.0193061945803603!GO:0016859;cis-trans isomerase activity;0.0203841708182629!GO:0032200;telomere organization and biogenesis;0.0207352303332666!GO:0000723;telomere maintenance;0.0207352303332666!GO:0008632;apoptotic program;0.0208511644095826!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0209495222492974!GO:0035004;phosphoinositide 3-kinase activity;0.0209692508972341!GO:0016303;1-phosphatidylinositol-3-kinase activity;0.0209692508972341!GO:0043022;ribosome binding;0.0211107768437116!GO:0008250;oligosaccharyl transferase complex;0.0214063146818801!GO:0030133;transport vesicle;0.0216633302844108!GO:0007041;lysosomal transport;0.0218914370670339!GO:0005484;SNAP receptor activity;0.021896407047944!GO:0046456;icosanoid biosynthetic process;0.0221631820804411!GO:0005070;SH3/SH2 adaptor activity;0.0226622487866763!GO:0046966;thyroid hormone receptor binding;0.0227942829289121!GO:0019377;glycolipid catabolic process;0.022814972526539!GO:0006950;response to stress;0.022946098699377!GO:0050681;androgen receptor binding;0.0232262922066814!GO:0003746;translation elongation factor activity;0.0232455038904723!GO:0000339;RNA cap binding;0.0232569673473639!GO:0051052;regulation of DNA metabolic process;0.0236662117585655!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0238652686419413!GO:0004192;cathepsin D activity;0.0245411138910753!GO:0030131;clathrin adaptor complex;0.0249787249685904!GO:0042158;lipoprotein biosynthetic process;0.0253726002637239!GO:0005791;rough endoplasmic reticulum;0.0253993129953096!GO:0008180;signalosome;0.026663120240125!GO:0005057;receptor signaling protein activity;0.0266727045452704!GO:0000119;mediator complex;0.026799058838393!GO:0051087;chaperone binding;0.0269845099641014!GO:0043241;protein complex disassembly;0.0270657469829837!GO:0046588;negative regulation of calcium-dependent cell-cell adhesion;0.0274078862314156!GO:0046586;regulation of calcium-dependent cell-cell adhesion;0.0274078862314156!GO:0003702;RNA polymerase II transcription factor activity;0.0276634147019631!GO:0044438;microbody part;0.0278074117947514!GO:0044439;peroxisomal part;0.0278074117947514!GO:0006468;protein amino acid phosphorylation;0.0278660461697407!GO:0001727;lipid kinase activity;0.0282515770403055!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0282597294227759!GO:0008168;methyltransferase activity;0.0285620434818537!GO:0030374;ligand-dependent nuclear receptor transcription coactivator activity;0.0285620434818537!GO:0004563;beta-N-acetylhexosaminidase activity;0.0286437209560147!GO:0006284;base-excision repair;0.0286604031673549!GO:0006506;GPI anchor biosynthetic process;0.028733142673963!GO:0030503;regulation of cell redox homeostasis;0.0288269127797204!GO:0030149;sphingolipid catabolic process;0.028873929683077!GO:0016741;transferase activity, transferring one-carbon groups;0.0289947264963893!GO:0043624;cellular protein complex disassembly;0.0289947264963893!GO:0006555;methionine metabolic process;0.0290323351531583!GO:0003725;double-stranded RNA binding;0.0293766271023258!GO:0043086;negative regulation of catalytic activity;0.029794801798851!GO:0031625;ubiquitin protein ligase binding;0.029922786138454!GO:0005092;GDP-dissociation inhibitor activity;0.0300229302155542!GO:0051338;regulation of transferase activity;0.030078083316484!GO:0005876;spindle microtubule;0.030078083316484!GO:0031123;RNA 3'-end processing;0.0313336533964049!GO:0032508;DNA duplex unwinding;0.0315249824545867!GO:0032392;DNA geometric change;0.0315249824545867!GO:0016791;phosphoric monoester hydrolase activity;0.0315604575370261!GO:0042770;DNA damage response, signal transduction;0.0316953250119476!GO:0045792;negative regulation of cell size;0.0319936475132252!GO:0018196;peptidyl-asparagine modification;0.0320847561120237!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0320847561120237!GO:0006944;membrane fusion;0.0322890531284687!GO:0030508;thiol-disulfide exchange intermediate activity;0.0327882175010909!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.033036732830026!GO:0045926;negative regulation of growth;0.0330794911857028!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0330794911857028!GO:0032981;mitochondrial respiratory chain complex I assembly;0.033092622187875!GO:0010257;NADH dehydrogenase complex assembly;0.033092622187875!GO:0033108;mitochondrial respiratory chain complex assembly;0.033092622187875!GO:0006516;glycoprotein catabolic process;0.0334721622672785!GO:0008538;proteasome activator activity;0.0336239922525442!GO:0006007;glucose catabolic process;0.0341236096650515!GO:0005850;eukaryotic translation initiation factor 2 complex;0.034171061329135!GO:0006354;RNA elongation;0.0342879256847122!GO:0040029;regulation of gene expression, epigenetic;0.034525682428578!GO:0004464;leukotriene-C4 synthase activity;0.0347392341564526!GO:0050811;GABA receptor binding;0.0347392341564526!GO:0030041;actin filament polymerization;0.0348122282093612!GO:0044272;sulfur compound biosynthetic process;0.0353179220744064!GO:0043407;negative regulation of MAP kinase activity;0.035497138701275!GO:0007259;JAK-STAT cascade;0.0355957415585054!GO:0048518;positive regulation of biological process;0.0356713979099231!GO:0006635;fatty acid beta-oxidation;0.0358246376862637!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0358344416684453!GO:0043549;regulation of kinase activity;0.0363118726673096!GO:0016272;prefoldin complex;0.0365915337326944!GO:0005832;chaperonin-containing T-complex;0.0372284671618686!GO:0051059;NF-kappaB binding;0.0372284671618686!GO:0042393;histone binding;0.0375760695973162!GO:0030308;negative regulation of cell growth;0.03786968273402!GO:0000781;chromosome, telomeric region;0.0379643873026717!GO:0005095;GTPase inhibitor activity;0.0385049708139843!GO:0030433;ER-associated protein catabolic process;0.0385772343903224!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0385772343903224!GO:0008022;protein C-terminus binding;0.0385772343903224!GO:0031903;microbody membrane;0.0393996584928009!GO:0005778;peroxisomal membrane;0.0393996584928009!GO:0009066;aspartate family amino acid metabolic process;0.0394566964819278!GO:0016788;hydrolase activity, acting on ester bonds;0.0398751000439657!GO:0006505;GPI anchor metabolic process;0.040080013907265!GO:0005758;mitochondrial intermembrane space;0.0413891777106341!GO:0016860;intramolecular oxidoreductase activity;0.0414123672237728!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.0415032986394676!GO:0005784;translocon complex;0.0423525959369789!GO:0045859;regulation of protein kinase activity;0.0423825262632349!GO:0004003;ATP-dependent DNA helicase activity;0.0432630619446901!GO:0008320;protein transmembrane transporter activity;0.043492384709191!GO:0009112;nucleobase metabolic process;0.0442643363143651!GO:0006268;DNA unwinding during replication;0.0443023283304185!GO:0004398;histidine decarboxylase activity;0.0443880641315027!GO:0022884;macromolecule transmembrane transporter activity;0.0465244322473746!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0465244322473746!GO:0007004;telomere maintenance via telomerase;0.0472966970114822!GO:0007021;tubulin folding;0.0477887282943056!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0477888373006443!GO:0006595;polyamine metabolic process;0.0484778382959869!GO:0002448;mast cell mediated immunity;0.0491805962728288!GO:0043303;mast cell degranulation;0.0491805962728288!GO:0022411;cellular component disassembly;0.0494028528615819!GO:0006378;mRNA polyadenylation;0.0497525652191009 | |sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.13341167518645e-241!GO:0043227;membrane-bound organelle;4.56928324722982e-212!GO:0043231;intracellular membrane-bound organelle;1.00045611131882e-211!GO:0043226;organelle;9.05988299731312e-199!GO:0043229;intracellular organelle;5.98182219676545e-198!GO:0005737;cytoplasm;4.48047147765162e-160!GO:0044422;organelle part;1.37572552015942e-132!GO:0044446;intracellular organelle part;1.14078180706058e-130!GO:0044444;cytoplasmic part;4.1594544311172e-120!GO:0044237;cellular metabolic process;3.1357824615295e-101!GO:0044238;primary metabolic process;5.68825778123729e-101!GO:0005634;nucleus;2.99045222968547e-97!GO:0043170;macromolecule metabolic process;1.02231884591549e-96!GO:0032991;macromolecular complex;1.3072569805929e-88!GO:0044428;nuclear part;8.13210341546878e-72!GO:0030529;ribonucleoprotein complex;1.84922452780146e-71!GO:0003723;RNA binding;2.36699142978696e-68!GO:0043283;biopolymer metabolic process;5.3556380225131e-65!GO:0043233;organelle lumen;3.61300495316985e-63!GO:0031974;membrane-enclosed lumen;3.61300495316985e-63!GO:0005515;protein binding;4.91413754461186e-58!GO:0005739;mitochondrion;2.62464291384688e-54!GO:0010467;gene expression;1.6992679192567e-51!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.77557151661901e-51!GO:0033036;macromolecule localization;2.54748937911238e-51!GO:0015031;protein transport;8.47155235670493e-50!GO:0019538;protein metabolic process;7.71239433167514e-48!GO:0045184;establishment of protein localization;1.14054044931772e-47!GO:0031090;organelle membrane;3.1575882404913e-47!GO:0008104;protein localization;5.59153962553871e-47!GO:0043234;protein complex;1.13564422546642e-45!GO:0006396;RNA processing;4.81511148346588e-44!GO:0044267;cellular protein metabolic process;5.26462609669783e-44!GO:0044260;cellular macromolecule metabolic process;2.94763720900311e-43!GO:0016071;mRNA metabolic process;4.11145548097117e-43!GO:0031981;nuclear lumen;2.62941953158245e-42!GO:0006412;translation;1.82229426077747e-41!GO:0016043;cellular component organization and biogenesis;1.29037887685214e-38!GO:0005840;ribosome;5.29834622700185e-38!GO:0044429;mitochondrial part;4.77247161355003e-37!GO:0005829;cytosol;6.80271355018651e-37!GO:0003676;nucleic acid binding;1.97654585037718e-36!GO:0006397;mRNA processing;2.93536954564391e-36!GO:0008380;RNA splicing;4.73122493022645e-36!GO:0031967;organelle envelope;1.15269921161479e-35!GO:0031975;envelope;2.64605404656882e-35!GO:0046907;intracellular transport;4.54356714938749e-35!GO:0009058;biosynthetic process;7.38151387985147e-34!GO:0009059;macromolecule biosynthetic process;1.07398861911019e-33!GO:0065003;macromolecular complex assembly;1.72853064845847e-32!GO:0006259;DNA metabolic process;1.8849210554014e-32!GO:0003735;structural constituent of ribosome;1.8849210554014e-32!GO:0006996;organelle organization and biogenesis;1.73708713668428e-31!GO:0044249;cellular biosynthetic process;1.91146224434498e-31!GO:0006886;intracellular protein transport;2.75604668824074e-31!GO:0033279;ribosomal subunit;7.24377960593275e-29!GO:0022607;cellular component assembly;1.10545161301785e-28!GO:0000166;nucleotide binding;4.93637092175171e-28!GO:0051649;establishment of cellular localization;6.54080948218014e-28!GO:0005654;nucleoplasm;8.77288245315253e-28!GO:0016070;RNA metabolic process;3.89783368878639e-27!GO:0051641;cellular localization;4.04860750873572e-27!GO:0005681;spliceosome;2.73064894875988e-26!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.38889573746487e-25!GO:0005740;mitochondrial envelope;7.52535329274508e-25!GO:0019866;organelle inner membrane;2.51216768641593e-24!GO:0031966;mitochondrial membrane;2.40963140455617e-23!GO:0005830;cytosolic ribosome (sensu Eukaryota);4.0230695522341e-23!GO:0007049;cell cycle;1.89651565905499e-22!GO:0044445;cytosolic part;2.332637294909e-22!GO:0005743;mitochondrial inner membrane;4.51131436855103e-22!GO:0044451;nucleoplasm part;6.76160726200255e-22!GO:0043228;non-membrane-bound organelle;1.06369682271479e-21!GO:0043232;intracellular non-membrane-bound organelle;1.06369682271479e-21!GO:0006119;oxidative phosphorylation;1.42219928627804e-21!GO:0006512;ubiquitin cycle;8.01514893300957e-21!GO:0012505;endomembrane system;2.06406080267237e-20!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;4.07284057986593e-20!GO:0016462;pyrophosphatase activity;4.3043415288283e-20!GO:0016817;hydrolase activity, acting on acid anhydrides;4.79361223396297e-20!GO:0032553;ribonucleotide binding;8.23409248086856e-20!GO:0032555;purine ribonucleotide binding;8.23409248086856e-20!GO:0043412;biopolymer modification;1.35023562312488e-19!GO:0017111;nucleoside-triphosphatase activity;2.47166782321599e-19!GO:0017076;purine nucleotide binding;4.59889604180289e-19!GO:0051276;chromosome organization and biogenesis;4.63599100580885e-19!GO:0044455;mitochondrial membrane part;1.49835937980467e-18!GO:0044265;cellular macromolecule catabolic process;2.30448064911472e-18!GO:0006974;response to DNA damage stimulus;3.48172830296276e-18!GO:0016874;ligase activity;3.65366664140109e-18!GO:0005694;chromosome;8.63562661985255e-18!GO:0022618;protein-RNA complex assembly;1.01222005579957e-17!GO:0008134;transcription factor binding;1.58729217707738e-17!GO:0006464;protein modification process;1.81342791755564e-17!GO:0022402;cell cycle process;2.4157102683304e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;2.4763940415798e-17!GO:0019941;modification-dependent protein catabolic process;3.59692791531615e-17!GO:0043632;modification-dependent macromolecule catabolic process;3.59692791531615e-17!GO:0044257;cellular protein catabolic process;4.24763521201393e-17!GO:0005524;ATP binding;4.82574458831686e-17!GO:0006511;ubiquitin-dependent protein catabolic process;5.59282749833154e-17!GO:0048770;pigment granule;1.08159592441718e-16!GO:0042470;melanosome;1.08159592441718e-16!GO:0006325;establishment and/or maintenance of chromatin architecture;1.08344037687465e-16!GO:0032559;adenyl ribonucleotide binding;1.74550221061067e-16!GO:0006323;DNA packaging;6.98051511503371e-16!GO:0043687;post-translational protein modification;8.23134095872227e-16!GO:0044427;chromosomal part;1.37815892861711e-15!GO:0043285;biopolymer catabolic process;1.41193795595103e-15!GO:0030554;adenyl nucleotide binding;1.41193795595103e-15!GO:0005746;mitochondrial respiratory chain;1.45682259930287e-15!GO:0044248;cellular catabolic process;2.54581321980941e-15!GO:0016604;nuclear body;4.3222046544299e-15!GO:0015935;small ribosomal subunit;4.74733296927817e-15!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;4.9626950283905e-15!GO:0000502;proteasome complex (sensu Eukaryota);5.44231401977285e-15!GO:0016192;vesicle-mediated transport;5.61577058454513e-15!GO:0006281;DNA repair;6.4823336063637e-15!GO:0005794;Golgi apparatus;8.2591061221116e-15!GO:0031980;mitochondrial lumen;1.48345771757626e-14!GO:0005759;mitochondrial matrix;1.48345771757626e-14!GO:0015934;large ribosomal subunit;1.59320868540655e-14!GO:0005730;nucleolus;1.8098435883599e-14!GO:0005783;endoplasmic reticulum;2.04096443438253e-14!GO:0009057;macromolecule catabolic process;2.19950114455076e-14!GO:0012501;programmed cell death;2.65360660636723e-14!GO:0006915;apoptosis;3.39971970522115e-14!GO:0008135;translation factor activity, nucleic acid binding;4.38337520734807e-14!GO:0050136;NADH dehydrogenase (quinone) activity;4.64425802645631e-14!GO:0003954;NADH dehydrogenase activity;4.64425802645631e-14!GO:0008137;NADH dehydrogenase (ubiquinone) activity;4.64425802645631e-14!GO:0006457;protein folding;5.40458852604409e-14!GO:0000278;mitotic cell cycle;8.4428647179876e-14!GO:0050794;regulation of cellular process;8.55664418640362e-14!GO:0008219;cell death;1.75851240415503e-13!GO:0016265;death;1.75851240415503e-13!GO:0065004;protein-DNA complex assembly;2.02670965434004e-13!GO:0006333;chromatin assembly or disassembly;3.26757099647205e-13!GO:0030163;protein catabolic process;3.37579656067067e-13!GO:0006605;protein targeting;6.70707314279396e-13!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.0333573821695e-12!GO:0051186;cofactor metabolic process;1.20212813477499e-12!GO:0042775;organelle ATP synthesis coupled electron transport;1.2819709330047e-12!GO:0042773;ATP synthesis coupled electron transport;1.2819709330047e-12!GO:0000398;nuclear mRNA splicing, via spliceosome;1.84697007265161e-12!GO:0000375;RNA splicing, via transesterification reactions;1.84697007265161e-12!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.84697007265161e-12!GO:0048193;Golgi vesicle transport;2.47997934180523e-12!GO:0016607;nuclear speck;2.47997934180523e-12!GO:0016887;ATPase activity;2.50048793296043e-12!GO:0044432;endoplasmic reticulum part;2.80764029406397e-12!GO:0030964;NADH dehydrogenase complex (quinone);3.59257946077462e-12!GO:0045271;respiratory chain complex I;3.59257946077462e-12!GO:0005747;mitochondrial respiratory chain complex I;3.59257946077462e-12!GO:0042623;ATPase activity, coupled;4.89850894598581e-12!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);6.99108605015947e-12!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;7.95412713999009e-12!GO:0006793;phosphorus metabolic process;8.0002321835133e-12!GO:0006796;phosphate metabolic process;8.0002321835133e-12!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);8.39586888038234e-12!GO:0022403;cell cycle phase;1.26278961254794e-11!GO:0003712;transcription cofactor activity;1.31146687458999e-11!GO:0005635;nuclear envelope;1.96915739487903e-11!GO:0006413;translational initiation;2.5646360213524e-11!GO:0003743;translation initiation factor activity;2.72083063467416e-11!GO:0006446;regulation of translational initiation;6.55976994371794e-11!GO:0009719;response to endogenous stimulus;7.31014835168353e-11!GO:0051726;regulation of cell cycle;1.14020723904367e-10!GO:0019222;regulation of metabolic process;1.36626772960837e-10!GO:0006732;coenzyme metabolic process;1.37049648522054e-10!GO:0000074;regulation of progression through cell cycle;1.37293994301221e-10!GO:0008639;small protein conjugating enzyme activity;1.55719377017083e-10!GO:0000785;chromatin;1.60826944749783e-10!GO:0044453;nuclear membrane part;1.93130210297214e-10!GO:0016568;chromatin modification;2.18173909728261e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;2.54321590523381e-10!GO:0000087;M phase of mitotic cell cycle;3.21115198322815e-10!GO:0051082;unfolded protein binding;3.63713812968552e-10!GO:0051301;cell division;3.69177394073292e-10!GO:0031965;nuclear membrane;3.69177394073292e-10!GO:0042175;nuclear envelope-endoplasmic reticulum network;3.73987218661443e-10!GO:0016310;phosphorylation;4.12365595331675e-10!GO:0004842;ubiquitin-protein ligase activity;4.48653683692588e-10!GO:0006913;nucleocytoplasmic transport;5.99396119637833e-10!GO:0019787;small conjugating protein ligase activity;6.18328075577187e-10!GO:0007067;mitosis;6.33969471280948e-10!GO:0004386;helicase activity;6.62753946139476e-10!GO:0005789;endoplasmic reticulum membrane;7.17275216195115e-10!GO:0051169;nuclear transport;1.02972814516913e-09!GO:0050657;nucleic acid transport;1.05534332572086e-09!GO:0051236;establishment of RNA localization;1.05534332572086e-09!GO:0050658;RNA transport;1.05534332572086e-09!GO:0006334;nucleosome assembly;1.11265326803201e-09!GO:0005768;endosome;1.18070554588418e-09!GO:0006403;RNA localization;2.03751710940623e-09!GO:0005761;mitochondrial ribosome;2.45646632834147e-09!GO:0000313;organellar ribosome;2.45646632834147e-09!GO:0031497;chromatin assembly;2.55446881844528e-09!GO:0019829;cation-transporting ATPase activity;2.99348610855452e-09!GO:0008565;protein transporter activity;3.43946381912005e-09!GO:0042254;ribosome biogenesis and assembly;3.6038602971967e-09!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;4.42578449107427e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;5.10631616624313e-09!GO:0000279;M phase;5.92984769289952e-09!GO:0050789;regulation of biological process;6.21467927402517e-09!GO:0006260;DNA replication;8.51834553439268e-09!GO:0005773;vacuole;9.78849899956812e-09!GO:0006366;transcription from RNA polymerase II promoter;1.13412744530246e-08!GO:0016881;acid-amino acid ligase activity;1.13765729828391e-08!GO:0005793;ER-Golgi intermediate compartment;1.15228675954882e-08!GO:0009056;catabolic process;1.21035579653436e-08!GO:0008026;ATP-dependent helicase activity;1.25887408368562e-08!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.64210845925507e-08!GO:0016740;transferase activity;1.87166901727618e-08!GO:0031323;regulation of cellular metabolic process;2.22826871351327e-08!GO:0048523;negative regulation of cellular process;2.22826871351327e-08!GO:0015986;ATP synthesis coupled proton transport;2.22826871351327e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;2.22826871351327e-08!GO:0042981;regulation of apoptosis;2.33720271280151e-08!GO:0043067;regulation of programmed cell death;3.19737472123334e-08!GO:0015078;hydrogen ion transmembrane transporter activity;3.36327275698172e-08!GO:0005643;nuclear pore;3.72617498970516e-08!GO:0051028;mRNA transport;5.46806707757434e-08!GO:0043566;structure-specific DNA binding;5.71364491493333e-08!GO:0006163;purine nucleotide metabolic process;5.72425546075097e-08!GO:0065002;intracellular protein transport across a membrane;5.85439053913672e-08!GO:0003697;single-stranded DNA binding;6.19103184251189e-08!GO:0051246;regulation of protein metabolic process;6.35658503524449e-08!GO:0016787;hydrolase activity;7.26335481850097e-08!GO:0016772;transferase activity, transferring phosphorus-containing groups;8.23530124238852e-08!GO:0006164;purine nucleotide biosynthetic process;1.22722431663712e-07!GO:0003713;transcription coactivator activity;1.24172639825832e-07!GO:0009055;electron carrier activity;1.2740940849262e-07!GO:0006888;ER to Golgi vesicle-mediated transport;1.27428350100753e-07!GO:0031982;vesicle;1.55543682810988e-07!GO:0009060;aerobic respiration;1.68128867915627e-07!GO:0009259;ribonucleotide metabolic process;1.97614579137871e-07!GO:0006350;transcription;2.18887219946914e-07!GO:0000323;lytic vacuole;2.18887219946914e-07!GO:0005764;lysosome;2.18887219946914e-07!GO:0009150;purine ribonucleotide metabolic process;2.26038502076634e-07!GO:0051188;cofactor biosynthetic process;2.40043849218412e-07!GO:0048519;negative regulation of biological process;2.77472683079271e-07!GO:0006754;ATP biosynthetic process;2.94281010519283e-07!GO:0006753;nucleoside phosphate metabolic process;2.94281010519283e-07!GO:0044431;Golgi apparatus part;3.11464975896608e-07!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;3.32455218615129e-07!GO:0016469;proton-transporting two-sector ATPase complex;3.37053056374442e-07!GO:0031988;membrane-bound vesicle;3.38930412447712e-07!GO:0046930;pore complex;3.45765210680856e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;3.6829131950765e-07!GO:0009144;purine nucleoside triphosphate metabolic process;3.6829131950765e-07!GO:0046034;ATP metabolic process;3.9062737501884e-07!GO:0010468;regulation of gene expression;3.9062737501884e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;4.13531164364818e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;4.13531164364818e-07!GO:0005839;proteasome core complex (sensu Eukaryota);4.31097373063655e-07!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;4.43562230545365e-07!GO:0009152;purine ribonucleotide biosynthetic process;4.60876099115342e-07!GO:0006461;protein complex assembly;5.41637872045406e-07!GO:0009199;ribonucleoside triphosphate metabolic process;5.67448679167275e-07!GO:0045333;cellular respiration;5.70268724841096e-07!GO:0017038;protein import;5.87815583123943e-07!GO:0009141;nucleoside triphosphate metabolic process;6.29643515758126e-07!GO:0009142;nucleoside triphosphate biosynthetic process;6.91225804657069e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;6.91225804657069e-07!GO:0030532;small nuclear ribonucleoprotein complex;7.43234210341849e-07!GO:0015630;microtubule cytoskeleton;7.8106926026282e-07!GO:0031410;cytoplasmic vesicle;8.30457545845363e-07!GO:0009260;ribonucleotide biosynthetic process;9.73414899274104e-07!GO:0016023;cytoplasmic membrane-bound vesicle;1.18399132546886e-06!GO:0045786;negative regulation of progression through cell cycle;1.2000469092862e-06!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;1.34722421105237e-06!GO:0006364;rRNA processing;1.38814389029527e-06!GO:0007243;protein kinase cascade;1.47244312628907e-06!GO:0030120;vesicle coat;1.50810217351291e-06!GO:0030662;coated vesicle membrane;1.50810217351291e-06!GO:0032446;protein modification by small protein conjugation;1.54789984489291e-06!GO:0048475;coated membrane;1.58594035534995e-06!GO:0030117;membrane coat;1.58594035534995e-06!GO:0007249;I-kappaB kinase/NF-kappaB cascade;1.58601089100251e-06!GO:0043069;negative regulation of programmed cell death;1.81712270351666e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;1.90793460074872e-06!GO:0000245;spliceosome assembly;1.91492250018325e-06!GO:0007242;intracellular signaling cascade;1.93318008243764e-06!GO:0016072;rRNA metabolic process;2.08736237030535e-06!GO:0043066;negative regulation of apoptosis;2.22635196760564e-06!GO:0004298;threonine endopeptidase activity;2.47594188714354e-06!GO:0006916;anti-apoptosis;2.83370137175489e-06!GO:0016567;protein ubiquitination;3.08618596565399e-06!GO:0006099;tricarboxylic acid cycle;3.3482877391073e-06!GO:0046356;acetyl-CoA catabolic process;3.3482877391073e-06!GO:0009108;coenzyme biosynthetic process;3.4758045369982e-06!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;3.53012731417865e-06!GO:0004812;aminoacyl-tRNA ligase activity;3.53012731417865e-06!GO:0016875;ligase activity, forming carbon-oxygen bonds;3.53012731417865e-06!GO:0016779;nucleotidyltransferase activity;3.73005289198881e-06!GO:0006399;tRNA metabolic process;3.83819110293798e-06!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.96490076441272e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;4.2011721738952e-06!GO:0008270;zinc ion binding;4.43202120582311e-06!GO:0005813;centrosome;4.56737934213854e-06!GO:0019899;enzyme binding;5.07950998601382e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;5.09617734825977e-06!GO:0045259;proton-transporting ATP synthase complex;5.17960455135483e-06!GO:0016563;transcription activator activity;5.86080181608394e-06!GO:0044440;endosomal part;5.86942908494946e-06!GO:0010008;endosome membrane;5.86942908494946e-06!GO:0007264;small GTPase mediated signal transduction;6.02472098510376e-06!GO:0043038;amino acid activation;6.4045416185473e-06!GO:0006418;tRNA aminoacylation for protein translation;6.4045416185473e-06!GO:0043039;tRNA aminoacylation;6.4045416185473e-06!GO:0008654;phospholipid biosynthetic process;6.61025776500103e-06!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;6.90038627440163e-06!GO:0006084;acetyl-CoA metabolic process;6.98202757750801e-06!GO:0006613;cotranslational protein targeting to membrane;7.54780561817556e-06!GO:0005770;late endosome;7.8955084682394e-06!GO:0000151;ubiquitin ligase complex;8.71721527637131e-06!GO:0003724;RNA helicase activity;9.62535841793726e-06!GO:0005525;GTP binding;1.01323959303878e-05!GO:0003924;GTPase activity;1.16972851985578e-05!GO:0006752;group transfer coenzyme metabolic process;1.1710510001351e-05!GO:0030384;phosphoinositide metabolic process;1.27739076390756e-05!GO:0005815;microtubule organizing center;1.32393353365094e-05!GO:0007005;mitochondrion organization and biogenesis;1.57672044033631e-05!GO:0032774;RNA biosynthetic process;1.57672044033631e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;1.58189132035469e-05!GO:0015399;primary active transmembrane transporter activity;1.58189132035469e-05!GO:0006818;hydrogen transport;1.69326409600814e-05!GO:0065007;biological regulation;1.84652723571773e-05!GO:0000786;nucleosome;1.88145324818012e-05!GO:0006351;transcription, DNA-dependent;1.884650006554e-05!GO:0015992;proton transport;1.98736687265444e-05!GO:0004674;protein serine/threonine kinase activity;2.49404986604968e-05!GO:0016197;endosome transport;2.61979378049818e-05!GO:0006402;mRNA catabolic process;2.62930901555892e-05!GO:0005798;Golgi-associated vesicle;2.78875636212949e-05!GO:0051187;cofactor catabolic process;2.85287383099196e-05!GO:0065009;regulation of a molecular function;3.0171265383517e-05!GO:0006612;protein targeting to membrane;3.15781622974164e-05!GO:0000139;Golgi membrane;3.2697964183375e-05!GO:0009109;coenzyme catabolic process;3.82471299985123e-05!GO:0006650;glycerophospholipid metabolic process;4.37416019113392e-05!GO:0046914;transition metal ion binding;4.64260098178894e-05!GO:0009117;nucleotide metabolic process;5.20971468061775e-05!GO:0051168;nuclear export;5.39045913850069e-05!GO:0016363;nuclear matrix;5.58020298723726e-05!GO:0045449;regulation of transcription;5.76430068135006e-05!GO:0045045;secretory pathway;5.90070643167821e-05!GO:0051170;nuclear import;6.03734356188912e-05!GO:0005769;early endosome;6.16884130106031e-05!GO:0032561;guanyl ribonucleotide binding;8.21737493546103e-05!GO:0019001;guanyl nucleotide binding;8.21737493546103e-05!GO:0016251;general RNA polymerase II transcription factor activity;8.97632411035918e-05!GO:0005819;spindle;9.99496984478481e-05!GO:0006606;protein import into nucleus;0.000119554686947565!GO:0051329;interphase of mitotic cell cycle;0.000123654205722878!GO:0003677;DNA binding;0.000124044396243072!GO:0003729;mRNA binding;0.000128551389949037!GO:0006261;DNA-dependent DNA replication;0.000163819990190528!GO:0032940;secretion by cell;0.000197444366374513!GO:0003690;double-stranded DNA binding;0.000213447518277506!GO:0005885;Arp2/3 protein complex;0.000214252699245926!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00021726114170699!GO:0051325;interphase;0.000221177856800872!GO:0043492;ATPase activity, coupled to movement of substances;0.000228139747106355!GO:0008186;RNA-dependent ATPase activity;0.000232966282565559!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000234891698042114!GO:0016564;transcription repressor activity;0.000265108752440878!GO:0006352;transcription initiation;0.00026603004062057!GO:0051427;hormone receptor binding;0.000277111846014891!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000279277528171885!GO:0043623;cellular protein complex assembly;0.000280390159023305!GO:0008610;lipid biosynthetic process;0.000285847665925913!GO:0031252;leading edge;0.000295875651127106!GO:0031324;negative regulation of cellular metabolic process;0.000303838422327421!GO:0046467;membrane lipid biosynthetic process;0.000308011729461057!GO:0030695;GTPase regulator activity;0.000316436265764033!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000327089648918999!GO:0006891;intra-Golgi vesicle-mediated transport;0.000405746821475403!GO:0051789;response to protein stimulus;0.000411087930464354!GO:0006986;response to unfolded protein;0.000411087930464354!GO:0043021;ribonucleoprotein binding;0.000427485765182785!GO:0006643;membrane lipid metabolic process;0.000438157875565994!GO:0006401;RNA catabolic process;0.000446189682776207!GO:0022890;inorganic cation transmembrane transporter activity;0.000497708080499824!GO:0006355;regulation of transcription, DNA-dependent;0.000503781893357574!GO:0035257;nuclear hormone receptor binding;0.000514466872835994!GO:0005774;vacuolar membrane;0.000556085219601202!GO:0016491;oxidoreductase activity;0.000627561304768647!GO:0048471;perinuclear region of cytoplasm;0.000633416345592959!GO:0006302;double-strand break repair;0.000637038946473515!GO:0000775;chromosome, pericentric region;0.000649039993237567!GO:0004004;ATP-dependent RNA helicase activity;0.000689064163401767!GO:0006091;generation of precursor metabolites and energy;0.000708721299458157!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000720112676036993!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000798130756474472!GO:0003899;DNA-directed RNA polymerase activity;0.000805219915162832!GO:0030521;androgen receptor signaling pathway;0.0008231137834033!GO:0008047;enzyme activator activity;0.000830659480101205!GO:0009892;negative regulation of metabolic process;0.000843952829094831!GO:0003714;transcription corepressor activity;0.000843952829094831!GO:0046489;phosphoinositide biosynthetic process;0.000855870715840656!GO:0009967;positive regulation of signal transduction;0.000863813392344443!GO:0006417;regulation of translation;0.000980828590128432!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000992820599644323!GO:0030518;steroid hormone receptor signaling pathway;0.000998075911010113!GO:0046474;glycerophospholipid biosynthetic process;0.00102072097807741!GO:0050790;regulation of catalytic activity;0.00104039963283334!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00109786406978269!GO:0016301;kinase activity;0.00115883344706366!GO:0006310;DNA recombination;0.00116507189338614!GO:0045454;cell redox homeostasis;0.00137567588729363!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0014198262196576!GO:0007050;cell cycle arrest;0.00144064311952711!GO:0031968;organelle outer membrane;0.00144771795354756!GO:0000075;cell cycle checkpoint;0.00148758485265466!GO:0005096;GTPase activator activity;0.00150708738184509!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00154691359171728!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00154691359171728!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00154691359171728!GO:0005667;transcription factor complex;0.00155635416125639!GO:0048500;signal recognition particle;0.00161108124832028!GO:0044437;vacuolar part;0.00162319294464047!GO:0030659;cytoplasmic vesicle membrane;0.00162918494140095!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.00164971379759806!GO:0019867;outer membrane;0.0016637772326478!GO:0019372;lipoxygenase pathway;0.00169656743026342!GO:0051252;regulation of RNA metabolic process;0.00175174116872372!GO:0000287;magnesium ion binding;0.00184234454960089!GO:0004428;inositol or phosphatidylinositol kinase activity;0.00185437440910116!GO:0022406;membrane docking;0.00192202430568419!GO:0048278;vesicle docking;0.00192202430568419!GO:0030658;transport vesicle membrane;0.0019574998104444!GO:0012506;vesicle membrane;0.00197945734601876!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.00210051784532483!GO:0033116;ER-Golgi intermediate compartment membrane;0.00217266157057225!GO:0007040;lysosome organization and biogenesis;0.00218112074450126!GO:0031072;heat shock protein binding;0.00222431927246198!GO:0006383;transcription from RNA polymerase III promoter;0.00225721404214783!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00237757243272214!GO:0030522;intracellular receptor-mediated signaling pathway;0.00243345784611903!GO:0006414;translational elongation;0.00248723657542275!GO:0048522;positive regulation of cellular process;0.00249284311432602!GO:0005741;mitochondrial outer membrane;0.00249284311432602!GO:0015980;energy derivation by oxidation of organic compounds;0.00259380251570056!GO:0005637;nuclear inner membrane;0.00260060253924821!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00269398329496227!GO:0043681;protein import into mitochondrion;0.00270255013084733!GO:0006904;vesicle docking during exocytosis;0.0030299616921288!GO:0003684;damaged DNA binding;0.003105653455877!GO:0016481;negative regulation of transcription;0.00312609559498433!GO:0031326;regulation of cellular biosynthetic process;0.00319213244557008!GO:0007034;vacuolar transport;0.00322404539504916!GO:0004527;exonuclease activity;0.00322404539504916!GO:0000776;kinetochore;0.00325220195463127!GO:0006405;RNA export from nucleus;0.00328439904536222!GO:0005762;mitochondrial large ribosomal subunit;0.00330418045817961!GO:0000315;organellar large ribosomal subunit;0.00330418045817961!GO:0005657;replication fork;0.00334233684621981!GO:0006644;phospholipid metabolic process;0.00335584212501669!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00338285097169525!GO:0045047;protein targeting to ER;0.00338285097169525!GO:0005048;signal sequence binding;0.00340175778149852!GO:0046519;sphingoid metabolic process;0.00341658940924648!GO:0030660;Golgi-associated vesicle membrane;0.00354473238052184!GO:0007033;vacuole organization and biogenesis;0.00357182328003398!GO:0006672;ceramide metabolic process;0.00357258322772911!GO:0015631;tubulin binding;0.00358950641982834!GO:0033673;negative regulation of kinase activity;0.00366049206544712!GO:0006469;negative regulation of protein kinase activity;0.00366049206544712!GO:0005788;endoplasmic reticulum lumen;0.00368750426321514!GO:0008287;protein serine/threonine phosphatase complex;0.00386797781810485!GO:0006917;induction of apoptosis;0.00388427071989824!GO:0005765;lysosomal membrane;0.00390038026693719!GO:0030127;COPII vesicle coat;0.00391088711145028!GO:0012507;ER to Golgi transport vesicle membrane;0.00391088711145028!GO:0007265;Ras protein signal transduction;0.00393216011000589!GO:0007059;chromosome segregation;0.00406056039057829!GO:0044433;cytoplasmic vesicle part;0.00418532540775082!GO:0030663;COPI coated vesicle membrane;0.00419847796633063!GO:0030126;COPI vesicle coat;0.00419847796633063!GO:0051920;peroxiredoxin activity;0.00420027933949302!GO:0007051;spindle organization and biogenesis;0.00422126249631753!GO:0031902;late endosome membrane;0.00425158140890606!GO:0030176;integral to endoplasmic reticulum membrane;0.0042649670342286!GO:0000314;organellar small ribosomal subunit;0.00432774894393102!GO:0005763;mitochondrial small ribosomal subunit;0.00432774894393102!GO:0043488;regulation of mRNA stability;0.00434051715035263!GO:0043487;regulation of RNA stability;0.00434051715035263!GO:0009165;nucleotide biosynthetic process;0.004372523762137!GO:0008234;cysteine-type peptidase activity;0.004372523762137!GO:0004261;cathepsin G activity;0.00439565197840978!GO:0005083;small GTPase regulator activity;0.00443523270982456!GO:0051348;negative regulation of transferase activity;0.00448074699120444!GO:0047485;protein N-terminus binding;0.00461406922866255!GO:0030134;ER to Golgi transport vesicle;0.00467927529031358!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00475893822138616!GO:0012502;induction of programmed cell death;0.005125091212946!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00542450425726241!GO:0001726;ruffle;0.0056007776216907!GO:0033367;protein localization in mast cell secretory granule;0.0056007776216907!GO:0033365;protein localization in organelle;0.0056007776216907!GO:0033371;T cell secretory granule organization and biogenesis;0.0056007776216907!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.0056007776216907!GO:0033375;protease localization in T cell secretory granule;0.0056007776216907!GO:0042629;mast cell granule;0.0056007776216907!GO:0033377;maintenance of protein localization in T cell secretory granule;0.0056007776216907!GO:0033364;mast cell secretory granule organization and biogenesis;0.0056007776216907!GO:0033380;granzyme B localization in T cell secretory granule;0.0056007776216907!GO:0033379;maintenance of protease localization in T cell secretory granule;0.0056007776216907!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.0056007776216907!GO:0033368;protease localization in mast cell secretory granule;0.0056007776216907!GO:0033366;protein localization in secretory granule;0.0056007776216907!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.0056007776216907!GO:0033374;protein localization in T cell secretory granule;0.0056007776216907!GO:0016853;isomerase activity;0.0056007776216907!GO:0043065;positive regulation of apoptosis;0.00565016672354852!GO:0008312;7S RNA binding;0.00578583136436408!GO:0000082;G1/S transition of mitotic cell cycle;0.00582401724151927!GO:0030137;COPI-coated vesicle;0.00605583308587757!GO:0030880;RNA polymerase complex;0.00606041101789095!GO:0030867;rough endoplasmic reticulum membrane;0.00616422737650305!GO:0009889;regulation of biosynthetic process;0.00616422737650305!GO:0035258;steroid hormone receptor binding;0.00631691069271279!GO:0048487;beta-tubulin binding;0.00658842736145723!GO:0003711;transcription elongation regulator activity;0.00663223635991583!GO:0016126;sterol biosynthetic process;0.00667724089806075!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00669777677718107!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00682004136383109!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00682004136383109!GO:0043068;positive regulation of programmed cell death;0.00703442083512525!GO:0007088;regulation of mitosis;0.00709454193258185!GO:0008629;induction of apoptosis by intracellular signals;0.00710585717894053!GO:0000209;protein polyubiquitination;0.00737650935147595!GO:0008017;microtubule binding;0.00740609243229215!GO:0046854;phosphoinositide phosphorylation;0.00741405784742151!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00741405784742151!GO:0016584;nucleosome positioning;0.00764431172407783!GO:0005874;microtubule;0.00777745774335912!GO:0006633;fatty acid biosynthetic process;0.00777745774335912!GO:0035035;histone acetyltransferase binding;0.00777745774335912!GO:0006611;protein export from nucleus;0.00777745774335912!GO:0003678;DNA helicase activity;0.00778441153880233!GO:0006607;NLS-bearing substrate import into nucleus;0.00793585008847898!GO:0000049;tRNA binding;0.00793585008847898!GO:0019752;carboxylic acid metabolic process;0.00821954582709403!GO:0005669;transcription factor TFIID complex;0.00835994299918876!GO:0030258;lipid modification;0.0084248206372565!GO:0030118;clathrin coat;0.0088764582627506!GO:0018193;peptidyl-amino acid modification;0.00896946821513304!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00896946821513304!GO:0000428;DNA-directed RNA polymerase complex;0.00896946821513304!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00920854614187698!GO:0046483;heterocycle metabolic process;0.00920854614187698!GO:0019843;rRNA binding;0.00933715036435975!GO:0006626;protein targeting to mitochondrion;0.00937849363181621!GO:0006839;mitochondrial transport;0.00949602580638359!GO:0019783;small conjugating protein-specific protease activity;0.00963093045655631!GO:0000096;sulfur amino acid metabolic process;0.00983165911553142!GO:0006289;nucleotide-excision repair;0.00996613588967455!GO:0004843;ubiquitin-specific protease activity;0.00999536725825964!GO:0006082;organic acid metabolic process;0.010028987754467!GO:0008094;DNA-dependent ATPase activity;0.0102015077698436!GO:0004518;nuclease activity;0.0106464464269282!GO:0007006;mitochondrial membrane organization and biogenesis;0.0106875974916226!GO:0005684;U2-dependent spliceosome;0.0109023989447931!GO:0044255;cellular lipid metabolic process;0.0109604285970322!GO:0016044;membrane organization and biogenesis;0.0110647698797653!GO:0006509;membrane protein ectodomain proteolysis;0.0111502652012367!GO:0033619;membrane protein proteolysis;0.0111502652012367!GO:0003682;chromatin binding;0.011717575375472!GO:0031901;early endosome membrane;0.0118637856310691!GO:0051539;4 iron, 4 sulfur cluster binding;0.0123349630967099!GO:0005020;stem cell factor receptor activity;0.0123349630967099!GO:0008139;nuclear localization sequence binding;0.0125208211568106!GO:0042802;identical protein binding;0.0132177455522573!GO:0009966;regulation of signal transduction;0.0132205258254867!GO:0006661;phosphatidylinositol biosynthetic process;0.0133350832110774!GO:0044452;nucleolar part;0.0135204108791664!GO:0046834;lipid phosphorylation;0.0137351771907065!GO:0006338;chromatin remodeling;0.0137943534945323!GO:0016407;acetyltransferase activity;0.0137943534945323!GO:0006695;cholesterol biosynthetic process;0.0138118928975629!GO:0051540;metal cluster binding;0.0139642036129534!GO:0051536;iron-sulfur cluster binding;0.0139642036129534!GO:0051287;NAD binding;0.0139642036129534!GO:0044262;cellular carbohydrate metabolic process;0.0141169209203305!GO:0030036;actin cytoskeleton organization and biogenesis;0.0142973475725857!GO:0015036;disulfide oxidoreductase activity;0.0143183041188416!GO:0006376;mRNA splice site selection;0.0144278434481627!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0144278434481627!GO:0005869;dynactin complex;0.0144695359782645!GO:0060090;molecular adaptor activity;0.0145489956585992!GO:0032984;macromolecular complex disassembly;0.014828305281149!GO:0046488;phosphatidylinositol metabolic process;0.0148922012916433!GO:0022415;viral reproductive process;0.0151575116611951!GO:0016408;C-acyltransferase activity;0.015160146456011!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0152617547972827!GO:0016311;dephosphorylation;0.0152875084327769!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0153434957386898!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.0153434957386898!GO:0045576;mast cell activation;0.0157220775342618!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0161313912432114!GO:0030119;AP-type membrane coat adaptor complex;0.0161845896233492!GO:0005942;phosphoinositide 3-kinase complex;0.0161849547783796!GO:0006497;protein amino acid lipidation;0.0162465934828633!GO:0004221;ubiquitin thiolesterase activity;0.0169392234012927!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.0170110225484844!GO:0000059;protein import into nucleus, docking;0.0171345110465352!GO:0016790;thiolester hydrolase activity;0.0171378231862907!GO:0007052;mitotic spindle organization and biogenesis;0.0171446484509508!GO:0006740;NADPH regeneration;0.0173951835686915!GO:0006098;pentose-phosphate shunt;0.0173951835686915!GO:0004177;aminopeptidase activity;0.0175940065333457!GO:0000228;nuclear chromosome;0.0178095460897987!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0178095460897987!GO:0015002;heme-copper terminal oxidase activity;0.0178095460897987!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0178095460897987!GO:0004129;cytochrome-c oxidase activity;0.0178095460897987!GO:0007030;Golgi organization and biogenesis;0.0179225778713611!GO:0009615;response to virus;0.0180135541860322!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0180135541860322!GO:0033033;negative regulation of myeloid cell apoptosis;0.0180135541860322!GO:0001803;regulation of type III hypersensitivity;0.0180135541860322!GO:0032733;positive regulation of interleukin-10 production;0.0180135541860322!GO:0033025;regulation of mast cell apoptosis;0.0180135541860322!GO:0001805;positive regulation of type III hypersensitivity;0.0180135541860322!GO:0033023;mast cell homeostasis;0.0180135541860322!GO:0002431;Fc receptor mediated stimulatory signaling pathway;0.0180135541860322!GO:0033032;regulation of myeloid cell apoptosis;0.0180135541860322!GO:0001802;type III hypersensitivity;0.0180135541860322!GO:0033028;myeloid cell apoptosis;0.0180135541860322!GO:0042590;antigen processing and presentation of exogenous peptide antigen via MHC class I;0.0180135541860322!GO:0033026;negative regulation of mast cell apoptosis;0.0180135541860322!GO:0033024;mast cell apoptosis;0.0180135541860322!GO:0004722;protein serine/threonine phosphatase activity;0.0180982770388606!GO:0046394;carboxylic acid biosynthetic process;0.0180982770388606!GO:0016053;organic acid biosynthetic process;0.0180982770388606!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0185289455994785!GO:0007093;mitotic cell cycle checkpoint;0.0187854892004836!GO:0031124;mRNA 3'-end processing;0.018960403003045!GO:0004576;oligosaccharyl transferase activity;0.0189665136342473!GO:0000118;histone deacetylase complex;0.0191282585355141!GO:0015923;mannosidase activity;0.0193061945803603!GO:0016859;cis-trans isomerase activity;0.0203841708182629!GO:0032200;telomere organization and biogenesis;0.0207352303332666!GO:0000723;telomere maintenance;0.0207352303332666!GO:0008632;apoptotic program;0.0208511644095826!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0209495222492974!GO:0035004;phosphoinositide 3-kinase activity;0.0209692508972341!GO:0016303;1-phosphatidylinositol-3-kinase activity;0.0209692508972341!GO:0043022;ribosome binding;0.0211107768437116!GO:0008250;oligosaccharyl transferase complex;0.0214063146818801!GO:0030133;transport vesicle;0.0216633302844108!GO:0007041;lysosomal transport;0.0218914370670339!GO:0005484;SNAP receptor activity;0.021896407047944!GO:0046456;icosanoid biosynthetic process;0.0221631820804411!GO:0005070;SH3/SH2 adaptor activity;0.0226622487866763!GO:0046966;thyroid hormone receptor binding;0.0227942829289121!GO:0019377;glycolipid catabolic process;0.022814972526539!GO:0006950;response to stress;0.022946098699377!GO:0050681;androgen receptor binding;0.0232262922066814!GO:0003746;translation elongation factor activity;0.0232455038904723!GO:0000339;RNA cap binding;0.0232569673473639!GO:0051052;regulation of DNA metabolic process;0.0236662117585655!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0238652686419413!GO:0004192;cathepsin D activity;0.0245411138910753!GO:0030131;clathrin adaptor complex;0.0249787249685904!GO:0042158;lipoprotein biosynthetic process;0.0253726002637239!GO:0005791;rough endoplasmic reticulum;0.0253993129953096!GO:0008180;signalosome;0.026663120240125!GO:0005057;receptor signaling protein activity;0.0266727045452704!GO:0000119;mediator complex;0.026799058838393!GO:0051087;chaperone binding;0.0269845099641014!GO:0043241;protein complex disassembly;0.0270657469829837!GO:0046588;negative regulation of calcium-dependent cell-cell adhesion;0.0274078862314156!GO:0046586;regulation of calcium-dependent cell-cell adhesion;0.0274078862314156!GO:0003702;RNA polymerase II transcription factor activity;0.0276634147019631!GO:0044438;microbody part;0.0278074117947514!GO:0044439;peroxisomal part;0.0278074117947514!GO:0006468;protein amino acid phosphorylation;0.0278660461697407!GO:0001727;lipid kinase activity;0.0282515770403055!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0282597294227759!GO:0008168;methyltransferase activity;0.0285620434818537!GO:0030374;ligand-dependent nuclear receptor transcription coactivator activity;0.0285620434818537!GO:0004563;beta-N-acetylhexosaminidase activity;0.0286437209560147!GO:0006284;base-excision repair;0.0286604031673549!GO:0006506;GPI anchor biosynthetic process;0.028733142673963!GO:0030503;regulation of cell redox homeostasis;0.0288269127797204!GO:0030149;sphingolipid catabolic process;0.028873929683077!GO:0016741;transferase activity, transferring one-carbon groups;0.0289947264963893!GO:0043624;cellular protein complex disassembly;0.0289947264963893!GO:0006555;methionine metabolic process;0.0290323351531583!GO:0003725;double-stranded RNA binding;0.0293766271023258!GO:0043086;negative regulation of catalytic activity;0.029794801798851!GO:0031625;ubiquitin protein ligase binding;0.029922786138454!GO:0005092;GDP-dissociation inhibitor activity;0.0300229302155542!GO:0051338;regulation of transferase activity;0.030078083316484!GO:0005876;spindle microtubule;0.030078083316484!GO:0031123;RNA 3'-end processing;0.0313336533964049!GO:0032508;DNA duplex unwinding;0.0315249824545867!GO:0032392;DNA geometric change;0.0315249824545867!GO:0016791;phosphoric monoester hydrolase activity;0.0315604575370261!GO:0042770;DNA damage response, signal transduction;0.0316953250119476!GO:0045792;negative regulation of cell size;0.0319936475132252!GO:0018196;peptidyl-asparagine modification;0.0320847561120237!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0320847561120237!GO:0006944;membrane fusion;0.0322890531284687!GO:0030508;thiol-disulfide exchange intermediate activity;0.0327882175010909!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.033036732830026!GO:0045926;negative regulation of growth;0.0330794911857028!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0330794911857028!GO:0032981;mitochondrial respiratory chain complex I assembly;0.033092622187875!GO:0010257;NADH dehydrogenase complex assembly;0.033092622187875!GO:0033108;mitochondrial respiratory chain complex assembly;0.033092622187875!GO:0006516;glycoprotein catabolic process;0.0334721622672785!GO:0008538;proteasome activator activity;0.0336239922525442!GO:0006007;glucose catabolic process;0.0341236096650515!GO:0005850;eukaryotic translation initiation factor 2 complex;0.034171061329135!GO:0006354;RNA elongation;0.0342879256847122!GO:0040029;regulation of gene expression, epigenetic;0.034525682428578!GO:0004464;leukotriene-C4 synthase activity;0.0347392341564526!GO:0050811;GABA receptor binding;0.0347392341564526!GO:0030041;actin filament polymerization;0.0348122282093612!GO:0044272;sulfur compound biosynthetic process;0.0353179220744064!GO:0043407;negative regulation of MAP kinase activity;0.035497138701275!GO:0007259;JAK-STAT cascade;0.0355957415585054!GO:0048518;positive regulation of biological process;0.0356713979099231!GO:0006635;fatty acid beta-oxidation;0.0358246376862637!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0358344416684453!GO:0043549;regulation of kinase activity;0.0363118726673096!GO:0016272;prefoldin complex;0.0365915337326944!GO:0005832;chaperonin-containing T-complex;0.0372284671618686!GO:0051059;NF-kappaB binding;0.0372284671618686!GO:0042393;histone binding;0.0375760695973162!GO:0030308;negative regulation of cell growth;0.03786968273402!GO:0000781;chromosome, telomeric region;0.0379643873026717!GO:0005095;GTPase inhibitor activity;0.0385049708139843!GO:0030433;ER-associated protein catabolic process;0.0385772343903224!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0385772343903224!GO:0008022;protein C-terminus binding;0.0385772343903224!GO:0031903;microbody membrane;0.0393996584928009!GO:0005778;peroxisomal membrane;0.0393996584928009!GO:0009066;aspartate family amino acid metabolic process;0.0394566964819278!GO:0016788;hydrolase activity, acting on ester bonds;0.0398751000439657!GO:0006505;GPI anchor metabolic process;0.040080013907265!GO:0005758;mitochondrial intermembrane space;0.0413891777106341!GO:0016860;intramolecular oxidoreductase activity;0.0414123672237728!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.0415032986394676!GO:0005784;translocon complex;0.0423525959369789!GO:0045859;regulation of protein kinase activity;0.0423825262632349!GO:0004003;ATP-dependent DNA helicase activity;0.0432630619446901!GO:0008320;protein transmembrane transporter activity;0.043492384709191!GO:0009112;nucleobase metabolic process;0.0442643363143651!GO:0006268;DNA unwinding during replication;0.0443023283304185!GO:0004398;histidine decarboxylase activity;0.0443880641315027!GO:0022884;macromolecule transmembrane transporter activity;0.0465244322473746!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0465244322473746!GO:0007004;telomere maintenance via telomerase;0.0472966970114822!GO:0007021;tubulin folding;0.0477887282943056!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0477888373006443!GO:0006595;polyamine metabolic process;0.0484778382959869!GO:0002448;mast cell mediated immunity;0.0491805962728288!GO:0043303;mast cell degranulation;0.0491805962728288!GO:0022411;cellular component disassembly;0.0494028528615819!GO:0006378;mRNA polyadenylation;0.0497525652191009 | ||
|sample_id=11563 | |sample_id=11563 |
Revision as of 20:22, 27 November 2014
Name: | Mast cell, donor1 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs12566 |
Sample type: | primary cells |
Genomic View: | UCSC |
CAGEd-oPOSSUM: | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12566
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12566
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.714 |
10 | 10 | 0.0581 |
100 | 100 | 0.301 |
101 | 101 | 0.349 |
102 | 102 | 0.0725 |
103 | 103 | 0.11 |
104 | 104 | 0.806 |
105 | 105 | 0.789 |
106 | 106 | 0.611 |
107 | 107 | 0.488 |
108 | 108 | 0.0961 |
109 | 109 | 0.00516 |
11 | 11 | 0.287 |
110 | 110 | 0.599 |
111 | 111 | 0.231 |
112 | 112 | 0.0922 |
113 | 113 | 0.0782 |
114 | 114 | 0.0386 |
115 | 115 | 0.845 |
116 | 116 | 0.628 |
117 | 117 | 0.00309 |
118 | 118 | 0.285 |
119 | 119 | 0.895 |
12 | 12 | 0.583 |
120 | 120 | 0.768 |
121 | 121 | 0.214 |
122 | 122 | 0.401 |
123 | 123 | 0.182 |
124 | 124 | 0.848 |
125 | 125 | 0.611 |
126 | 126 | 0.458 |
127 | 127 | 0.345 |
128 | 128 | 0.769 |
129 | 129 | 0.304 |
13 | 13 | 0.775 |
130 | 130 | 0.255 |
131 | 131 | 0.62 |
132 | 132 | 0.705 |
133 | 133 | 0.835 |
134 | 134 | 0.285 |
135 | 135 | 0.0323 |
136 | 136 | 0.0672 |
137 | 137 | 0.0761 |
138 | 138 | 0.19 |
139 | 139 | 0.477 |
14 | 14 | 0.27 |
140 | 140 | 0.272 |
141 | 141 | 0.299 |
142 | 142 | 0.419 |
143 | 143 | 0.588 |
144 | 144 | 0.121 |
145 | 145 | 0.288 |
146 | 146 | 0.857 |
147 | 147 | 0.0671 |
148 | 148 | 0.542 |
149 | 149 | 0.398 |
15 | 15 | 0.129 |
150 | 150 | 0.184 |
151 | 151 | 0.44 |
152 | 152 | 0.673 |
153 | 153 | 0.115 |
154 | 154 | 0.785 |
155 | 155 | 0.0103 |
156 | 156 | 0.921 |
157 | 157 | 0.802 |
158 | 158 | 0.164 |
159 | 159 | 0.986 |
16 | 16 | 0.623 |
160 | 160 | 0.141 |
161 | 161 | 0.797 |
162 | 162 | 0.937 |
163 | 163 | 0.99 |
164 | 164 | 0.337 |
165 | 165 | 0.511 |
166 | 166 | 0.00982 |
167 | 167 | 0.588 |
168 | 168 | 0.46 |
169 | 169 | 0.881 |
17 | 17 | 0.919 |
18 | 18 | 0.405 |
19 | 19 | 0.789 |
2 | 2 | 0.383 |
20 | 20 | 0.572 |
21 | 21 | 0.0173 |
22 | 22 | 0.213 |
23 | 23 | 0.408 |
24 | 24 | 0.0821 |
25 | 25 | 0.32 |
26 | 26 | 0.481 |
27 | 27 | 0.395 |
28 | 28 | 0.199 |
29 | 29 | 0.154 |
3 | 3 | 0.649 |
30 | 30 | 0.137 |
31 | 31 | 0.803 |
32 | 32 | 0.0863 |
33 | 33 | 0.644 |
34 | 34 | 0.958 |
35 | 35 | 0.749 |
36 | 36 | 0.555 |
37 | 37 | 0.165 |
38 | 38 | 0.367 |
39 | 39 | 0.348 |
4 | 4 | 0.868 |
40 | 40 | 0.228 |
41 | 41 | 0.951 |
42 | 42 | 0.618 |
43 | 43 | 0.741 |
44 | 44 | 0.652 |
45 | 45 | 0.976 |
46 | 46 | 0.604 |
47 | 47 | 0.299 |
48 | 48 | 0.345 |
49 | 49 | 0.7 |
5 | 5 | 0.885 |
50 | 50 | 0.483 |
51 | 51 | 0.341 |
52 | 52 | 0.432 |
53 | 53 | 0.489 |
54 | 54 | 0.365 |
55 | 55 | 0.887 |
56 | 56 | 0.563 |
57 | 57 | 0.985 |
58 | 58 | 0.017 |
59 | 59 | 0.628 |
6 | 6 | 0.619 |
60 | 60 | 0.958 |
61 | 61 | 0.0999 |
62 | 62 | 0.047 |
63 | 63 | 0.605 |
64 | 64 | 0.724 |
65 | 65 | 0.939 |
66 | 66 | 0.276 |
67 | 67 | 0.743 |
68 | 68 | 0.339 |
69 | 69 | 0.693 |
7 | 7 | 0.577 |
70 | 70 | 0.729 |
71 | 71 | 0.335 |
72 | 72 | 0.0354 |
73 | 73 | 0.198 |
74 | 74 | 0.121 |
75 | 75 | 0.113 |
76 | 76 | 0.821 |
77 | 77 | 0.224 |
78 | 78 | 0.00907 |
79 | 79 | 0.806 |
8 | 8 | 0.972 |
80 | 80 | 0.707 |
81 | 81 | 0.68 |
82 | 82 | 0.582 |
83 | 83 | 0.839 |
84 | 84 | 0.923 |
85 | 85 | 0.711 |
86 | 86 | 0.193 |
87 | 87 | 0.0833 |
88 | 88 | 0.211 |
89 | 89 | 0.247 |
9 | 9 | 0.891 |
90 | 90 | 0.161 |
91 | 91 | 0.995 |
92 | 92 | 0.791 |
93 | 93 | 0.299 |
94 | 94 | 0.198 |
95 | 95 | 9.01286e-5 |
96 | 96 | 0.415 |
97 | 97 | 0.485 |
98 | 98 | 0.495 |
99 | 99 | 0.336 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs12566
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0000261 mast cell- heparinase treated sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0000151 (secretory cell)
0002371 (somatic cell)
0000766 (myeloid leukocyte)
0002274 (histamine secreting cell)
0000219 (motile cell)
0000163 (endocrine cell)
0000457 (biogenic amine secreting cell)
0000738 (leukocyte)
0000255 (eukaryotic cell)
0000097 (mast cell)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
0000260 (mast cell sample)
0000261 (mast cell- heparinase treated sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)