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Coexpression cluster:C4599

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Full id: C4599_Preadipocyte_Synoviocyte_tenocyte_eye_retina_leiomyoblastoma_Adipocyte



Phase1 CAGE Peaks

Hg19::chr6:36922505..36922522,+p1@PI16
Hg19::chr6:36929675..36929699,+p@chr6:36929675..36929699
+
Hg19::chr6:36930905..36930916,+p10@PI16


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
fat cell2.05e-0715
Uber Anatomy
Ontology termp-valuen
adult organism1.87e-45115
neural tube9.41e-1657
neural rod9.41e-1657
future spinal cord9.41e-1657
neural keel9.41e-1657
regional part of brain8.57e-1559
neural plate2.06e-1386
presumptive neural plate2.06e-1386
anterior neural tube3.21e-1342
regional part of forebrain1.13e-1241
forebrain1.13e-1241
future forebrain1.13e-1241
neurectoderm5.14e-1290
brain1.60e-1169
future brain1.60e-1169
central nervous system4.89e-1182
regional part of nervous system2.34e-1094
nervous system2.34e-1094
telencephalon1.02e-0934
tube1.14e-09194
gray matter1.15e-0934
brain grey matter1.15e-0934
regional part of telencephalon2.16e-0933
anatomical cluster2.75e-09286
anatomical conduit2.80e-09241
organism subdivision5.07e-09365
cerebral hemisphere9.12e-0932
pre-chordal neural plate5.11e-0861
regional part of cerebral cortex5.42e-0822
anterior region of body7.31e-08129
craniocervical region7.31e-08129
primary circulatory organ7.87e-0827
neocortex3.83e-0720
splanchnic layer of lateral plate mesoderm4.15e-0784
head5.22e-07123


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.