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MCL coexpression mm9:856

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:126628600..126628612,-p@chr10:126628600..126628612
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Mm9::chr1:173286693..173286705,+p3@Pfdn2
Mm9::chr5:136387174..136387192,-p@chr5:136387174..136387192
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Mm9::chr5:136387318..136387336,-p@chr5:136387318..136387336
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Mm9::chr5:136387343..136387354,-p@chr5:136387343..136387354
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Mm9::chr5:136387416..136387428,-p@chr5:136387416..136387428
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Mm9::chr5:136387440..136387453,-p@chr5:136387440..136387453
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Mm9::chr7:31229435..31229449,-p@chr7:31229435..31229449
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0005080protein kinase C binding0.0207043861153407
GO:0016272prefoldin complex0.0207043861153407
GO:0019901protein kinase binding0.0444163745222791
GO:0019900kinase binding0.0444163745222791
GO:0019904protein domain specific binding0.0444163745222791
GO:0051082unfolded protein binding0.0444163745222791



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
central nervous system5.35e-3073
nervous system7.49e-3075
regional part of nervous system7.16e-2454
ectoderm-derived structure1.63e-2395
ectoderm1.63e-2395
presumptive ectoderm1.63e-2395
neural tube3.59e-2252
neural rod3.59e-2252
future spinal cord3.59e-2252
neural keel3.59e-2252
neurectoderm1.54e-2164
neural plate1.54e-2164
presumptive neural plate1.54e-2164
gray matter7.66e-2034
structure with developmental contribution from neural crest1.45e-1992
brain9.94e-1947
future brain9.94e-1947
regional part of brain2.68e-1846
anterior neural tube7.91e-1840
ecto-epithelium1.40e-1773
regional part of forebrain2.24e-1739
forebrain2.24e-1739
future forebrain2.24e-1739
pre-chordal neural plate1.05e-1649
brain grey matter1.82e-1629
regional part of telencephalon1.82e-1629
telencephalon1.82e-1629
cerebral cortex8.69e-1221
cerebral hemisphere8.69e-1221
pallium8.69e-1221
tube4.85e-10114
regional part of cerebral cortex8.75e-1017
anatomical conduit5.60e-08122
occipital lobe1.92e-0710
visual cortex1.92e-0710
neocortex1.92e-0710


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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