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MCL coexpression mm9:3138

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Phase1 CAGE Peaks

 Short description
Mm9::chr18:37501369..37501382,+p1@Pcdhb7
Mm9::chr18:37644609..37644682,+p1@Pcdhb17
Mm9::chr18:37663920..37663950,+p1@ENSMUST00000052179


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0007156homophilic cell adhesion1.59841215407587e-06
GO:0016337cell-cell adhesion1.23990510328889e-05
GO:0022610biological adhesion0.000141374341282812
GO:0007155cell adhesion0.000141374341282812
GO:0005509calcium ion binding0.000264337753872757
GO:0043169cation binding0.0146479629229864
GO:0046872metal ion binding0.0149456365494994
GO:0043167ion binding0.0149456365494994
GO:0005515protein binding0.0332932232185889
GO:0016021integral to membrane0.0462332639126207
GO:0031224intrinsic to membrane0.0462332639126207



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
electrically responsive cell4.26e-0939
electrically active cell4.26e-0939
neuron7.23e-0833
neuronal stem cell7.23e-0833
neuroblast7.23e-0833
electrically signaling cell7.23e-0833
CNS neuron (sensu Vertebrata)9.19e-0823
neuroblast (sensu Vertebrata)9.19e-0823

Uber Anatomy
Ontology termp-valuen
neurectoderm6.41e-2264
neural plate6.41e-2264
presumptive neural plate6.41e-2264
ecto-epithelium6.73e-2173
ectoderm-derived structure2.26e-2095
ectoderm2.26e-2095
presumptive ectoderm2.26e-2095
structure with developmental contribution from neural crest5.44e-2092
neural tube2.07e-1952
neural rod2.07e-1952
future spinal cord2.07e-1952
neural keel2.07e-1952
nervous system2.98e-1975
central nervous system3.21e-1973
regional part of nervous system6.87e-1954
pre-chordal neural plate1.13e-1849
brain2.80e-1747
future brain2.80e-1747
regional part of brain1.26e-1646
anterior neural tube7.76e-1640
regional part of forebrain2.93e-1539
forebrain2.93e-1539
future forebrain2.93e-1539
gray matter3.25e-1434
brain grey matter4.62e-1229
regional part of telencephalon4.62e-1229
telencephalon4.62e-1229
anatomical conduit5.81e-12122
tube1.15e-11114
multi-cellular organism4.80e-10333
cerebral cortex1.36e-0821
cerebral hemisphere1.36e-0821
pallium1.36e-0821
regional part of cerebral cortex2.47e-0717
occipital lobe2.73e-0710
visual cortex2.73e-0710
neocortex2.73e-0710
embryo2.95e-07320


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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