Personal tools

MCL coexpression mm9:3342

From FANTOM5_SSTAR

Revision as of 22:46, 26 November 2012 by Autoedit (talk | contribs)
Jump to: navigation, search


Phase1 CAGE Peaks

 Short description
Mm9::chr2:30122323..30122406,+p1@Phyhd1
Mm9::chr5:5514877..5514891,-p2@Cldn12
Mm9::chr5:5514906..5514918,-p4@Cldn12


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0051213dioxygenase activity0.0295120490852277
GO:0016702oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen0.0295120490852277
GO:0016701oxidoreductase activity, acting on single donors with incorporation of molecular oxygen0.0295120490852277
GO:0005923tight junction0.0295120490852277
GO:0043296apical junction complex0.0295120490852277
GO:0016327apicolateral plasma membrane0.0295120490852277
GO:0005911intercellular junction0.0420906041267709



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
non-terminally differentiated cell1.18e-1149
embryonic cell2.65e-1070
ectodermal cell2.01e-0944
neurectodermal cell2.01e-0944
neural cell3.92e-0943
electrically responsive cell6.74e-0839
electrically active cell6.74e-0839

Uber Anatomy
Ontology termp-valuen
tube2.49e-18114
anatomical conduit2.29e-17122
ectoderm-derived structure1.09e-1595
ectoderm1.09e-1595
presumptive ectoderm1.09e-1595
nervous system2.80e-1475
central nervous system6.35e-1473
anatomical cluster6.46e-12244
epithelial tube2.05e-1147
structure with developmental contribution from neural crest2.44e-1092
liver5.46e-1022
epithelial sac5.46e-1022
digestive gland5.46e-1022
epithelium of foregut-midgut junction5.46e-1022
anatomical boundary5.46e-1022
hepatobiliary system5.46e-1022
foregut-midgut junction5.46e-1022
hepatic diverticulum5.46e-1022
liver primordium5.46e-1022
septum transversum5.46e-1022
liver bud5.46e-1022
ecto-epithelium6.91e-1073
neurectoderm9.96e-1064
neural plate9.96e-1064
presumptive neural plate9.96e-1064
brain8.49e-0947
future brain8.49e-0947
digestive tract diverticulum9.16e-0923
sac9.16e-0923
exocrine gland1.01e-0825
exocrine system1.01e-0825
regional part of nervous system1.28e-0854
regional part of brain2.42e-0846
neural tube5.27e-0852
neural rod5.27e-0852
future spinal cord5.27e-0852
neural keel5.27e-0852
mesenchyme1.43e-0761
entire embryonic mesenchyme1.43e-0761
pre-chordal neural plate4.63e-0749
cell layer6.87e-07176


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}