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Coexpression cluster:C2700

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Full id: C2700_chorionic_lung_Fibroblast_Olfactory_Renal_Endothelial_Hepatic



Phase1 CAGE Peaks

Hg19::chr2:46602879..46602899,+p8@EPAS1
Hg19::chr2:46602901..46602926,+p7@EPAS1
Hg19::chr2:46605165..46605191,+p@chr2:46605165..46605191
+
Hg19::chr2:46607364..46607410,+p@chr2:46607364..46607410
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
mesodermal cell4.39e-10119
lining cell2.82e-0957
barrier cell2.82e-0957
epithelial cell6.50e-09254
endothelial cell2.51e-0835
meso-epithelial cell1.30e-0744
embryonic cell3.65e-07248
endothelial cell of vascular tree6.33e-0724
Uber Anatomy
Ontology termp-valuen
anatomical cluster3.32e-20286
multi-cellular organism1.09e-19659
epithelium6.01e-18309
anatomical conduit7.44e-18241
cell layer1.31e-17312
anatomical system3.97e-17625
anatomical group8.21e-17626
multi-tissue structure4.17e-14347
organism subdivision6.86e-13365
organ9.65e-13511
epithelial tube1.04e-12118
tube3.76e-12194
germ layer5.15e-12604
embryonic tissue5.15e-12604
presumptive structure5.15e-12604
epiblast (generic)5.15e-12604
embryonic structure5.63e-12605
developing anatomical structure5.63e-12605
embryo2.10e-11612
organ part1.88e-10219
splanchnic layer of lateral plate mesoderm5.04e-1084
unilaminar epithelium4.30e-09138
vasculature5.62e-0979
vascular system5.62e-0979
trunk5.63e-09216
adult organism7.80e-09115
endoderm-derived structure2.00e-08169
endoderm2.00e-08169
presumptive endoderm2.00e-08169
compound organ4.89e-0869
vessel6.46e-0869
trunk mesenchyme6.81e-08143
circulatory system2.31e-07113
mesenchyme3.08e-07238
entire embryonic mesenchyme3.08e-07238
subdivision of trunk5.88e-07113
primary circulatory organ6.36e-0727
mesoderm7.62e-07448
mesoderm-derived structure7.62e-07448
presumptive mesoderm7.62e-07448
primordium7.82e-07168


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.