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MCL coexpression mm9:1661

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Phase1 CAGE Peaks

 Short description
Mm9::chr14:122873999..122874022,+p@chr14:122873999..122874022
+
Mm9::chr14:122874619..122874634,+p1@Zic2
Mm9::chr14:122874718..122874729,+p3@Zic2
Mm9::chr9:91260797..91260807,+p@chr9:91260797..91260807
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Mm9::chr9:91263649..91263666,+p3@Zic4


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0048066pigmentation during development0.0408015330915254
GO:0001843neural tube closure0.0408015330915254
GO:0014020primary neural tube formation0.0408015330915254
GO:0001841neural tube formation0.0408015330915254
GO:0001839neural plate morphogenesis0.0408015330915254
GO:0001838embryonic epithelial tube formation0.0408015330915254
GO:0001840neural plate development0.0408015330915254
GO:0021915neural tube development0.0408015330915254
GO:0016331morphogenesis of embryonic epithelium0.0408015330915254
GO:0008270zinc ion binding0.0427512187222919
GO:0003677DNA binding0.0427512187222919



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
nervous system3.66e-3275
central nervous system8.75e-3273
regional part of nervous system2.00e-3054
neurectoderm4.65e-3064
neural plate4.65e-3064
presumptive neural plate4.65e-3064
ectoderm-derived structure1.52e-2995
ectoderm1.52e-2995
presumptive ectoderm1.52e-2995
neural tube2.24e-2852
neural rod2.24e-2852
future spinal cord2.24e-2852
neural keel2.24e-2852
ecto-epithelium3.67e-2573
brain3.76e-2547
future brain3.76e-2547
regional part of brain3.08e-2446
pre-chordal neural plate1.50e-2349
anterior neural tube1.22e-1940
regional part of forebrain2.57e-1939
forebrain2.57e-1939
future forebrain2.57e-1939
gray matter1.99e-1634
structure with developmental contribution from neural crest1.08e-1592
brain grey matter3.93e-1329
regional part of telencephalon3.93e-1329
telencephalon3.93e-1329
posterior neural tube2.86e-0912
chordal neural plate2.86e-0912
cerebral cortex1.37e-0721
cerebral hemisphere1.37e-0721
pallium1.37e-0721
basal ganglion1.99e-078
nuclear complex of neuraxis1.99e-078
aggregate regional part of brain1.99e-078
collection of basal ganglia1.99e-078
cerebral subcortex1.99e-078
diencephalon2.63e-0710
future diencephalon2.63e-0710


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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