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MCL coexpression mm9:733

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Phase1 CAGE Peaks

 Short description
Mm9::chr15:26291955..26291956,+p@chr15:26291955..26291956
+
Mm9::chr4:110256532..110256536,+p@chr4:110256532..110256536
+
Mm9::chr4:110262019..110262022,+p@chr4:110262019..110262022
+
Mm9::chr4:110325225..110325231,+p@chr4:110325225..110325231
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Mm9::chr4:151401911..151401934,+p@chr4:151401911..151401934
+
Mm9::chr5:125342568..125342602,+p2@Zfp664
Mm9::chr5:92444356..92444360,-p@chr5:92444356..92444360
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Mm9::chr5:92471656..92471727,-p1@Cdkl2
Mm9::chr6:53018556..53018650,-p1@Jazf1
Mm9::chr7:97129757..97129776,+p@chr7:97129757..97129776
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0035098ESC/E(Z) complex0.0370123163137112
GO:0006349genetic imprinting0.0370123163137112
GO:0035097histone methyltransferase complex0.0370123163137112
GO:0005634nucleus0.0370123163137112
GO:0017053transcriptional repressor complex0.0370123163137112
GO:0031519PcG protein complex0.0370123163137112
GO:0043283biopolymer metabolic process0.0370123163137112
GO:0001739sex chromatin0.0370123163137112
GO:0000803sex chromosome0.0370123163137112
GO:0045120pronucleus0.0370123163137112
GO:0016571histone methylation0.0370123163137112
GO:0044451nucleoplasm part0.0383916747404711
GO:0010468regulation of gene expression0.0383916747404711
GO:0005720nuclear heterochromatin0.0383916747404711
GO:0005654nucleoplasm0.0383916747404711
GO:0042054histone methyltransferase activity0.0383916747404711
GO:0008213protein amino acid alkylation0.0383916747404711
GO:0006479protein amino acid methylation0.0383916747404711
GO:0004693cyclin-dependent protein kinase activity0.0383916747404711
GO:0000790nuclear chromatin0.0383916747404711
GO:0008276protein methyltransferase activity0.0383916747404711
GO:0031981nuclear lumen0.0383916747404711
GO:0043170macromolecule metabolic process0.0383916747404711
GO:0016570histone modification0.0383916747404711
GO:0000792heterochromatin0.0385558823317547
GO:0016569covalent chromatin modification0.0385558823317547
GO:0031974membrane-enclosed lumen0.038814610994547
GO:0043233organelle lumen0.038814610994547
GO:0043414biopolymer methylation0.038814610994547
GO:0040029regulation of gene expression, epigenetic0.038814610994547
GO:0032259methylation0.0393031576574954
GO:0010467gene expression0.0423687115763379
GO:0003714transcription corepressor activity0.0449295376650605
GO:0044238primary metabolic process0.0449295376650605
GO:0044237cellular metabolic process0.0449295376650605
GO:0043231intracellular membrane-bound organelle0.0449295376650605
GO:0043227membrane-bound organelle0.0449295376650605
GO:0006139nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0464302673569337
GO:0044454nuclear chromosome part0.0464302673569337
GO:0044428nuclear part0.0491307095045673



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
neuron5.31e-0933
neuronal stem cell5.31e-0933
neuroblast5.31e-0933
electrically signaling cell5.31e-0933
CNS neuron (sensu Vertebrata)6.73e-0923
neuroblast (sensu Vertebrata)6.73e-0923

Uber Anatomy
Ontology termp-valuen
neurectoderm5.96e-2364
neural plate5.96e-2364
presumptive neural plate5.96e-2364
central nervous system8.53e-2273
regional part of nervous system3.31e-2154
ecto-epithelium8.95e-2173
ectoderm-derived structure1.10e-2095
ectoderm1.10e-2095
presumptive ectoderm1.10e-2095
nervous system3.93e-2075
neural tube5.77e-2052
neural rod5.77e-2052
future spinal cord5.77e-2052
neural keel5.77e-2052
pre-chordal neural plate1.10e-1849
brain2.00e-1747
future brain2.00e-1747
structure with developmental contribution from neural crest6.62e-1792
regional part of brain8.40e-1746
anterior neural tube3.92e-1640
regional part of forebrain1.46e-1539
forebrain1.46e-1539
future forebrain1.46e-1539
gray matter1.69e-1434
brain grey matter4.85e-1229
regional part of telencephalon4.85e-1229
telencephalon4.85e-1229
cerebral cortex6.80e-0921
cerebral hemisphere6.80e-0921
pallium6.80e-0921
regional part of cerebral cortex4.34e-0817
occipital lobe6.41e-0810
visual cortex6.41e-0810
neocortex6.41e-0810
tube2.09e-07114
anatomical conduit3.41e-07122
multi-cellular organism4.03e-07333


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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