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Coexpression cluster:C4096

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Full id: C4096_chorionic_Natural_mycosis_hairy_cord_CD4_CD8



Phase1 CAGE Peaks

Hg19::chr22:37523892..37523907,-p@chr22:37523892..37523907
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Hg19::chr22:37531413..37531430,-p@chr22:37531413..37531430
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Hg19::chr22:37540237..37540244,-p6@IL2RB


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
lymphoid lineage restricted progenitor cell1.93e-3252
lymphocyte1.15e-3153
common lymphoid progenitor1.15e-3153
T cell7.83e-3125
pro-T cell7.83e-3125
nucleate cell3.38e-3055
mature alpha-beta T cell5.55e-2718
alpha-beta T cell5.55e-2718
immature T cell5.55e-2718
mature T cell5.55e-2718
immature alpha-beta T cell5.55e-2718
nongranular leukocyte2.78e-20115
leukocyte6.77e-19136
hematopoietic cell9.19e-16177
circulating cell2.26e-156
hematopoietic lineage restricted progenitor cell3.31e-15120
CD4-positive, alpha-beta T cell1.91e-146
hematopoietic stem cell4.16e-14168
angioblastic mesenchymal cell4.16e-14168
CD8-positive, alpha-beta T cell3.36e-1311
hematopoietic oligopotent progenitor cell3.31e-12161
hematopoietic multipotent progenitor cell3.31e-12161
natural killer cell4.78e-093
pro-NK cell4.78e-093
single nucleate cell1.29e-083
mononuclear cell1.29e-083
chorionic membrane mesenchymal stem cell1.87e-083
naive T cell5.10e-083
basophil2.18e-073


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.