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MCL coexpression mm9:671

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Phase1 CAGE Peaks

 Short description
Mm9::chr14:122864041..122864099,-p@chr14:122864041..122864099
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Mm9::chr14:122864676..122864708,-p1@Zic5
Mm9::chr14:122873661..122873686,+p@chr14:122873661..122873686
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Mm9::chr14:122873694..122873710,+p@chr14:122873694..122873710
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Mm9::chr14:122879279..122879285,+p@chr14:122879279..122879285
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Mm9::chr9:91259711..91259725,-p@chr9:91259711..91259725
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Mm9::chr9:91260248..91260259,-p4@Zic1
Mm9::chr9:91262990..91263011,-p@chr9:91262990..91263011
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Mm9::chr9:91263173..91263220,+p2@Zic4
Mm9::chr9:91273474..91273484,+p11@Zic4
Mm9::chr9:91275527..91275544,+p@chr9:91275527..91275544
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0007417central nervous system development0.000483665690904929
GO:0001843neural tube closure0.000498947244351965
GO:0014020primary neural tube formation0.000498947244351965
GO:0001841neural tube formation0.000498947244351965
GO:0001839neural plate morphogenesis0.000498947244351965
GO:0001838embryonic epithelial tube formation0.000498947244351965
GO:0001840neural plate development0.000498947244351965
GO:0021915neural tube development0.000568641857073429
GO:0016331morphogenesis of embryonic epithelium0.000636282393872113
GO:0003677DNA binding0.000636282393872113
GO:0007399nervous system development0.000835223444455235
GO:0002009morphogenesis of an epithelium0.00136167516678533
GO:0035239tube morphogenesis0.00181898416272182
GO:0003676nucleic acid binding0.00213504303258981
GO:0007420brain development0.00243345122482529
GO:0048598embryonic morphogenesis0.00256023272294392
GO:0035295tube development0.00256023272294392
GO:0016337cell-cell adhesion0.0025884509832289
GO:0043009chordate embryonic development0.00269954463698739
GO:0009792embryonic development ending in birth or egg hatching0.00269954463698739
GO:0005634nucleus0.00625387709903602
GO:0008589regulation of smoothened signaling pathway0.00703697243384536
GO:0048731system development0.00703697243384536
GO:0048869cellular developmental process0.00703697243384536
GO:0030154cell differentiation0.00703697243384536
GO:0009790embryonic development0.00815239420749265
GO:0008270zinc ion binding0.0084646283988294
GO:0048856anatomical structure development0.00910520032603384
GO:0007275multicellular organismal development0.0116707777989934
GO:0022610biological adhesion0.0116707777989934
GO:0007155cell adhesion0.0116707777989934
GO:0007224smoothened signaling pathway0.0116707777989934
GO:0048066pigmentation during development0.0117203371206961
GO:0046914transition metal ion binding0.0125989430938281
GO:0032502developmental process0.0221024338513604
GO:0043231intracellular membrane-bound organelle0.0221024338513604
GO:0043227membrane-bound organelle0.0221024338513604
GO:0043169cation binding0.0288932550287507
GO:0009653anatomical structure morphogenesis0.0318776641924248
GO:0030900forebrain development0.0319765146532927
GO:0043229intracellular organelle0.0319765146532927
GO:0043226organelle0.0319765146532927
GO:0046872metal ion binding0.0322470960645324
GO:0043167ion binding0.0334005799442731
GO:0048513organ development0.0386898252973023
GO:0032501multicellular organismal process0.045169113728162



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
CNS neuron (sensu Vertebrata)6.87e-1323
neuroblast (sensu Vertebrata)6.87e-1323
neural cell5.12e-1143
ectodermal cell1.38e-1044
neurectodermal cell1.38e-1044
non-terminally differentiated cell1.02e-0849
neuron4.62e-0833
neuronal stem cell4.62e-0833
neuroblast4.62e-0833
electrically signaling cell4.62e-0833

Uber Anatomy
Ontology termp-valuen
neurectoderm9.21e-2064
neural plate9.21e-2064
presumptive neural plate9.21e-2064
central nervous system1.74e-1973
nervous system1.39e-1875
regional part of nervous system1.70e-1854
neural tube6.46e-1852
neural rod6.46e-1852
future spinal cord6.46e-1852
neural keel6.46e-1852
ectoderm-derived structure8.68e-1895
ectoderm8.68e-1895
presumptive ectoderm8.68e-1895
ecto-epithelium1.56e-1673
regional part of brain5.02e-1346
pre-chordal neural plate1.09e-1249
brain1.48e-1247
future brain1.48e-1247
posterior neural tube1.09e-1012
chordal neural plate1.09e-1012
structure with developmental contribution from neural crest1.82e-1092
anterior neural tube1.27e-0940
regional part of forebrain3.11e-0939
forebrain3.11e-0939
future forebrain3.11e-0939
gray matter2.05e-0834
spinal cord4.56e-076
dorsal region element4.56e-076
dorsum4.56e-076
regional part of spinal cord9.34e-075
gray matter of spinal cord9.34e-075


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.261277
MA0004.10.330313
MA0006.10.186435
MA0007.10.316976
MA0009.10.743257
MA0014.10.144697
MA0017.10.598706
MA0019.10.567591
MA0024.11.6716
MA0025.10.971686
MA0027.12.37948
MA0028.10.194782
MA0029.10.679737
MA0030.10.686088
MA0031.10.651724
MA0038.10.462726
MA0040.10.755433
MA0041.10.263922
MA0042.10.252679
MA0043.10.837621
MA0046.10.778239
MA0048.10.440822
MA0050.10.365212
MA0051.10.471092
MA0052.10.76328
MA0055.12.71747
MA0056.10
MA0057.12.63634
MA0058.10.246908
MA0059.10.714494
MA0060.10.395347
MA0061.10.884293
MA0063.10
MA0066.10.452472
MA0067.11.08124
MA0068.10.187364
MA0069.10.76361
MA0070.10.75417
MA0071.10.364454
MA0072.10.745922
MA0073.18.00317
MA0074.10.419185
MA0076.10.223625
MA0077.10.724865
MA0078.10.502121
MA0081.11.39097
MA0083.10.836845
MA0084.11.4063
MA0087.10.794721
MA0088.10.28966
MA0089.10
MA0090.10.299987
MA0091.10.342071
MA0092.10.300264
MA0093.10.20148
MA0095.10
MA0098.10
MA0100.10.408523
MA0101.10.265031
MA0103.10.216742
MA0105.11.95127
MA0106.11.26962
MA0107.10.607721
MA0108.20.589413
MA0109.10
MA0111.10.312463
MA0113.10.482899
MA0114.10.446898
MA0115.10.84036
MA0116.10.546914
MA0117.10.808813
MA0119.10.265536
MA0122.10.828211
MA0124.11.02871
MA0125.10.955734
MA0130.10
MA0131.10.563262
MA0132.10
MA0133.10
MA0135.10.873285
MA0136.10.437601
MA0139.10.103495
MA0140.10.408417
MA0141.10.233109
MA0142.10.63775
MA0143.10.49828
MA0144.10.147954
MA0145.10.57264
MA0146.11.40012
MA0147.10.157258
MA0148.10.344843
MA0149.10.269772
MA0062.20.0791588
MA0035.20.412747
MA0039.20.0387728
MA0138.20.555696
MA0002.20.343346
MA0137.20.230686
MA0104.20.11535
MA0047.20.46201
MA0112.20.57262
MA0065.20.314773
MA0150.10.316876
MA0151.10
MA0152.10.46211
MA0153.10.889592
MA0154.11.16232
MA0155.10.637282
MA0156.10.222905
MA0157.10.606944
MA0158.10
MA0159.10.165031
MA0160.10.347545
MA0161.10
MA0162.11.19805
MA0163.10.355774
MA0164.10.437937
MA0080.20.212408
MA0018.20.446948
MA0099.20.549696
MA0079.21.59098
MA0102.21.45844
MA0258.10.135621
MA0259.10.14914
MA0442.10
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