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Coexpression cluster:C1591: Difference between revisions

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{{Coexpression_clusters
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|full_id=C1591_CD4_CD19_CD8_Natural_Neutrophils_peripheral_Peripheral
|id=C1591
|ontology_enrichment_celltype=CL:0000037!4.45e-35!172;CL:0000566!4.45e-35!172;CL:0002032!5.65e-32!165;CL:0000837!5.65e-32!165;CL:0000988!5.80e-32!182;CL:0000738!8.47e-32!140;CL:0002031!9.48e-28!124;CL:0002087!3.19e-27!119;CL:0000763!2.12e-20!112;CL:0000049!2.12e-20!112;CL:0000766!1.27e-17!76;CL:0000860!1.83e-17!45;CL:0002057!5.74e-17!42;CL:0000839!1.02e-16!70;CL:0000557!2.15e-16!71;CL:0002009!7.65e-16!65;CL:0002194!4.35e-15!63;CL:0000576!4.35e-15!63;CL:0000040!4.35e-15!63;CL:0000559!4.35e-15!63;CL:0000542!1.04e-10!53;CL:0000051!1.04e-10!53;CL:0000838!2.51e-10!52
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0002390!1.94e-17!102;UBERON:0003061!1.94e-17!102;UBERON:0002193!2.52e-14!112;UBERON:0002371!3.50e-13!80;UBERON:0007023!1.60e-12!115;UBERON:0001474!2.16e-12!86;UBERON:0001049!2.14e-11!57;UBERON:0005068!2.14e-11!57;UBERON:0006241!2.14e-11!57;UBERON:0007135!2.14e-11!57;UBERON:0002780!8.62e-11!41;UBERON:0001890!8.62e-11!41;UBERON:0006240!8.62e-11!41;UBERON:0003080!3.36e-10!42;UBERON:0002020!1.63e-09!34;UBERON:0003528!1.63e-09!34;UBERON:0002791!8.23e-09!33;UBERON:0001893!9.47e-09!34;UBERON:0002405!1.80e-08!115;UBERON:0002616!3.83e-08!59;UBERON:0001869!3.92e-08!32;UBERON:0004765!4.62e-08!101;UBERON:0001434!4.62e-08!101;UBERON:0001017!5.20e-08!82;UBERON:0000955!5.84e-08!69;UBERON:0006238!5.84e-08!69;UBERON:0000073!1.39e-07!94;UBERON:0001016!1.39e-07!94;UBERON:0005743!4.76e-07!86
}}

Latest revision as of 11:48, 17 September 2013


Full id: C1591_CD4_CD19_CD8_Natural_Neutrophils_peripheral_Peripheral



Phase1 CAGE Peaks

Hg19::chr10:70092889..70092902,+p@chr10:70092889..70092902
+
Hg19::chr13:25885831..25885836,+p@chr13:25885831..25885836
+
Hg19::chr1:245025039..245025045,-p@chr1:245025039..245025045
-
Hg19::chr1:245025688..245025704,-p@chr1:245025688..245025704
-
Hg19::chr7:104719134..104719139,+p@chr7:104719134..104719139
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
hematopoietic stem cell9.72e-32168
angioblastic mesenchymal cell9.72e-32168
hematopoietic cell3.91e-29177
hematopoietic oligopotent progenitor cell6.99e-29161
hematopoietic multipotent progenitor cell6.99e-29161
leukocyte1.07e-28136
hematopoietic lineage restricted progenitor cell6.21e-25120
nongranular leukocyte1.02e-24115
myeloid cell1.13e-17108
common myeloid progenitor1.13e-17108
classical monocyte1.12e-1542
CD14-positive, CD16-negative classical monocyte1.12e-1542
myeloid leukocyte2.48e-1572
myeloid lineage restricted progenitor cell2.07e-1466
defensive cell7.53e-1448
phagocyte7.53e-1448
granulocyte monocyte progenitor cell1.53e-1367
macrophage dendritic cell progenitor2.88e-1361
monopoietic cell7.46e-1359
monocyte7.46e-1359
monoblast7.46e-1359
promonocyte7.46e-1359
nucleate cell2.74e-1155
lymphocyte1.19e-1053
common lymphoid progenitor1.19e-1053
lymphoid lineage restricted progenitor cell2.61e-1052
Uber Anatomy
Ontology termp-valuen
hematopoietic system2.23e-1498
blood island2.23e-1498
adult organism2.32e-13114
neural tube3.73e-1356
neural rod3.73e-1356
future spinal cord3.73e-1356
neural keel3.73e-1356
regional part of nervous system3.63e-1253
regional part of brain3.63e-1253
hemolymphoid system9.33e-12108
regional part of forebrain1.48e-1141
forebrain1.48e-1141
anterior neural tube1.48e-1141
future forebrain1.48e-1141
bone marrow3.11e-1076
bone element4.06e-1082
brain grey matter4.32e-1034
gray matter4.32e-1034
nervous system1.33e-0989
telencephalon2.20e-0934
regional part of telencephalon2.63e-0932
brain3.44e-0968
future brain3.44e-0968
central nervous system4.17e-0981
cerebral hemisphere9.13e-0932
neurectoderm1.16e-0886
immune system2.91e-0893
neural plate2.80e-0782
presumptive neural plate2.80e-0782
cerebral cortex7.04e-0725
pallium7.04e-0725


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.00991994
MA0004.10.626788
MA0006.10.452993
MA0007.10.606704
MA0009.11.11255
MA0014.10.0418333
MA0017.10.496101
MA0019.10.784036
MA0024.11.00439
MA0025.11.24931
MA0027.12.73598
MA0028.10.470679
MA0029.11.02437
MA0030.11.01252
MA0031.10.945567
MA0038.10.736268
MA0040.11.03042
MA0041.12.63789
MA0042.12.52778
MA0043.11.11288
MA0046.11.10134
MA0048.10.195817
MA0050.10.613347
MA0051.10.731787
MA0052.11.03442
MA0055.10.603517
MA0056.10
MA0057.10.189508
MA0058.10.523638
MA0059.10.522232
MA0060.10.321781
MA0061.10.291022
MA0063.10
MA0066.10.736721
MA0067.11.43651
MA0068.11.28241
MA0069.11.09737
MA0070.11.08584
MA0071.10.695094
MA0072.11.0812
MA0073.10.00220137
MA0074.10.730989
MA0076.10.540943
MA0077.11.07324
MA0078.10.836493
MA0081.10.522409
MA0083.11.12028
MA0084.11.62584
MA0087.11.07867
MA0088.10.132006
MA0089.10
MA0090.10.556637
MA0091.10.629594
MA0092.10.588959
MA0093.10.456342
MA0095.10
MA0098.10
MA0100.10.750974
MA0101.10.459973
MA0103.11.12656
MA0105.10.175503
MA0106.10.779931
MA0107.10.378225
MA0108.20.94238
MA0109.10
MA0111.10.5713
MA0113.10.797251
MA0114.10.372523
MA0115.11.35895
MA0116.10.382106
MA0117.11.1512
MA0119.10.504689
MA0122.11.17777
MA0124.11.31673
MA0125.11.23103
MA0130.10
MA0131.10.855546
MA0132.10
MA0133.10
MA0135.11.14377
MA0136.10.743749
MA0139.10.759606
MA0140.10.692258
MA0141.10.520334
MA0142.10.912455
MA0143.10.797437
MA0144.10.356507
MA0145.10.143698
MA0146.10.0359558
MA0147.10.386018
MA0148.10.653474
MA0149.10.681935
MA0062.20.284987
MA0035.20.691506
MA0039.20.0118463
MA0138.20.837782
MA0002.20.30855
MA0137.20.47779
MA0104.20.320919
MA0047.21.80892
MA0112.20.136971
MA0065.20.146576
MA0150.10.550239
MA0151.10
MA0152.10.69926
MA0153.11.21379
MA0154.10.172764
MA0155.10.130813
MA0156.10.480289
MA0157.10.883854
MA0158.10
MA0159.10.386729
MA0160.10.669748
MA0161.10
MA0162.10.0592265
MA0163.10.0439995
MA0164.10.810347
MA0080.20.456437
MA0018.20.781393
MA0099.20.699641
MA0079.20.00207114
MA0102.21.66336
MA0258.10.345771
MA0259.10.395396
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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