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Coexpression cluster:C3466

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Full id: C3466_thalamus_substantia_globus_CD14_spinal_parietal_corpus



Phase1 CAGE Peaks

Hg19::chr14:95725440..95725533,-p@chr14:95725440..95725533
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Hg19::chr14:95725547..95725558,-p@chr14:95725547..95725558
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Hg19::chr2:201599919..201599932,-p2@LOC100507140


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism6.69e-36115
neural tube3.43e-2757
neural rod3.43e-2757
future spinal cord3.43e-2757
neural keel3.43e-2757
central nervous system1.57e-2382
brain2.56e-2269
future brain2.56e-2269
anterior neural tube1.05e-2142
regional part of nervous system2.11e-2194
nervous system2.11e-2194
regional part of forebrain2.59e-2141
forebrain2.59e-2141
future forebrain2.59e-2141
regional part of brain8.20e-2159
neurectoderm1.21e-1890
neural plate2.77e-1886
presumptive neural plate2.77e-1886
gray matter4.87e-1834
brain grey matter4.87e-1834
telencephalon5.93e-1834
regional part of telencephalon2.47e-1733
cerebral hemisphere1.68e-1632
pre-chordal neural plate5.07e-1361
regional part of cerebral cortex5.70e-1322
ectoderm1.87e-12173
presumptive ectoderm1.87e-12173
ectoderm-derived structure5.10e-12169
cerebral cortex5.19e-1225
pallium5.19e-1225
neocortex1.34e-1120
head4.62e-11123
anterior region of body9.24e-11129
craniocervical region9.24e-11129
organ1.31e-10511
bone element2.29e-0886
bone marrow4.98e-0880
nucleus of brain9.23e-089
neural nucleus9.23e-089
basal ganglion1.25e-079
nuclear complex of neuraxis1.25e-079
aggregate regional part of brain1.25e-079
collection of basal ganglia1.25e-079
cerebral subcortex1.25e-079
brainstem8.22e-078
posterior neural tube9.65e-0715
chordal neural plate9.65e-0715


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.