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Coexpression cluster:C1863

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Full id: C1863_Multipotent_aorta_smooth_Olfactory_Chondrocyte_Preadipocyte_mesodermal



Phase1 CAGE Peaks

Hg19::chr20:17550489..17550543,+p3@DSTN
Hg19::chr20:17550544..17550559,+p6@DSTN
Hg19::chr20:17550575..17550596,+p5@DSTN
Hg19::chr20:17550691..17550782,+p1@DSTN
Hg19::chr20:17550786..17550804,+p2@DSTN


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
organism subdivision8.28e-20365
multi-tissue structure7.96e-19347
trunk9.95e-18216
multi-cellular organism5.75e-17659
mesenchyme8.57e-17238
entire embryonic mesenchyme8.57e-17238
anatomical system1.92e-13625
trunk mesenchyme3.30e-13143
anatomical group3.65e-13626
organ1.02e-11511
cell layer1.06e-10312
epithelium1.28e-10309
anatomical cluster2.81e-10286
embryo2.94e-10612
embryonic structure3.85e-10605
developing anatomical structure3.85e-10605
germ layer4.58e-10604
embryonic tissue4.58e-10604
presumptive structure4.58e-10604
epiblast (generic)4.58e-10604
organ part6.34e-10219
subdivision of trunk2.44e-09113
somite5.33e-0983
paraxial mesoderm5.33e-0983
presomitic mesoderm5.33e-0983
presumptive segmental plate5.33e-0983
trunk paraxial mesoderm5.33e-0983
presumptive paraxial mesoderm5.33e-0983
endoderm-derived structure1.52e-08169
endoderm1.52e-08169
presumptive endoderm1.52e-08169
digestive system2.04e-08155
digestive tract2.04e-08155
primitive gut2.04e-08155
anatomical space1.31e-07104
anatomical conduit1.95e-07241
surface structure2.05e-0795
immaterial anatomical entity2.08e-07126
primordium2.58e-07168
muscle tissue3.12e-0763
musculature3.12e-0763
musculature of body3.12e-0763
epithelial tube3.20e-07118
mesoderm6.22e-07448
mesoderm-derived structure6.22e-07448
presumptive mesoderm6.22e-07448
multilaminar epithelium6.69e-0782
skeletal muscle tissue8.72e-0761
striated muscle tissue8.72e-0761
myotome8.72e-0761


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.