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Coexpression cluster:C456

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Full id: C456_Fibroblast_Smooth_CD14_Preadipocyte_Lens_mesenchymal_serous



Phase1 CAGE Peaks

Hg19::chr5:82767555..82767575,+p1@VCAN
Hg19::chr5:82767585..82767607,+p2@VCAN
Hg19::chr5:82789361..82789380,+p13@VCAN
Hg19::chr5:82808116..82808153,+p12@VCAN
Hg19::chr5:82808155..82808193,+p9@VCAN
Hg19::chr5:82817501..82817514,+p11@VCAN
Hg19::chr5:82818036..82818054,+p14@VCAN
Hg19::chr5:82832922..82832942,+p@chr5:82832922..82832942
+
Hg19::chr5:82833507..82833521,+p@chr5:82833507..82833521
+
Hg19::chr5:82833713..82833727,+p@chr5:82833713..82833727
+
Hg19::chr5:82834000..82834017,+p@chr5:82834000..82834017
+
Hg19::chr5:82834804..82834842,+p@chr5:82834804..82834842
+
Hg19::chr5:82834843..82834902,+p@chr5:82834843..82834902
+
Hg19::chr5:82834954..82834973,+p@chr5:82834954..82834973
+
Hg19::chr5:82835000..82835031,+p@chr5:82835000..82835031
+
Hg19::chr5:82835043..82835057,+p@chr5:82835043..82835057
+
Hg19::chr5:82835589..82835617,+p@chr5:82835589..82835617
+
Hg19::chr5:82835837..82835870,+p@chr5:82835837..82835870
+
Hg19::chr5:82836231..82836261,+p@chr5:82836231..82836261
+
Hg19::chr5:82836392..82836413,+p@chr5:82836392..82836413
+
Hg19::chr5:82837130..82837153,+p8@VCAN
Hg19::chr5:82837460..82837472,+p15@VCAN


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Uber Anatomy
Ontology termp-valuen
musculoskeletal system4.12e-17167
multi-cellular organism1.15e-16659
anatomical system8.98e-14625
anatomical group1.87e-13626
skeletal muscle tissue1.07e-1161
striated muscle tissue1.07e-1161
myotome1.07e-1161
embryo1.95e-11612
muscle tissue2.10e-1163
musculature2.10e-1163
musculature of body2.10e-1163
somite3.51e-1183
paraxial mesoderm3.51e-1183
presomitic mesoderm3.51e-1183
presumptive segmental plate3.51e-1183
trunk paraxial mesoderm3.51e-1183
presumptive paraxial mesoderm3.51e-1183
tissue8.31e-11787
dermomyotome9.59e-1170
lateral plate mesoderm1.48e-10216
embryonic structure3.57e-10605
developing anatomical structure3.57e-10605
germ layer5.74e-10604
embryonic tissue5.74e-10604
presumptive structure5.74e-10604
epiblast (generic)5.74e-10604
mesoderm4.69e-09448
mesoderm-derived structure4.69e-09448
presumptive mesoderm4.69e-09448
heart3.47e-0824
primitive heart tube3.47e-0824
primary heart field3.47e-0824
anterior lateral plate mesoderm3.47e-0824
heart tube3.47e-0824
heart primordium3.47e-0824
cardiac mesoderm3.47e-0824
cardiogenic plate3.47e-0824
heart rudiment3.47e-0824
multilaminar epithelium1.22e-0782
primary circulatory organ1.46e-0727
cardiovascular system3.29e-07110
circulatory system4.02e-07113
Disease
Ontology termp-valuen
ovarian cancer2.10e-0814


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.