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Coexpression cluster:C2168

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Full id: C2168_hippocampus_occipital_temporal_parietal_neuroectodermal_amygdala_medial



Phase1 CAGE Peaks

Hg19::chr11:83167766..83167847,-p1@ENST00000420284
Hg19::chr11:84244945..84244949,-p@chr11:84244945..84244949
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Hg19::chr17:7787702..7787722,+p7@CHD3
Hg19::chr2:50155392..50155397,-p@chr2:50155392..50155397
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
central nervous system2.09e-3482
regional part of nervous system4.39e-3494
nervous system4.39e-3494
neural tube2.76e-3357
neural rod2.76e-3357
future spinal cord2.76e-3357
neural keel2.76e-3357
adult organism1.78e-29115
brain6.19e-2869
future brain6.19e-2869
regional part of brain1.10e-2759
neurectoderm1.60e-2790
regional part of forebrain6.73e-2741
forebrain6.73e-2741
future forebrain6.73e-2741
anterior neural tube1.18e-2542
neural plate3.63e-2586
presumptive neural plate3.63e-2586
gray matter1.63e-2234
brain grey matter1.63e-2234
telencephalon2.09e-2234
regional part of telencephalon8.93e-2233
cerebral hemisphere2.91e-2132
pre-chordal neural plate3.83e-1861
ectoderm5.86e-18173
presumptive ectoderm5.86e-18173
regional part of cerebral cortex1.74e-1722
cerebral cortex1.58e-1625
pallium1.58e-1625
anterior region of body2.81e-16129
craniocervical region2.81e-16129
ectoderm-derived structure3.15e-16169
neocortex5.43e-1620
head2.99e-15123
posterior neural tube1.04e-0815
chordal neural plate1.04e-0815
basal ganglion1.06e-079
nuclear complex of neuraxis1.06e-079
aggregate regional part of brain1.06e-079
collection of basal ganglia1.06e-079
cerebral subcortex1.06e-079
nucleus of brain1.88e-079
neural nucleus1.88e-079
segmental subdivision of nervous system2.01e-0713
temporal lobe4.14e-077
segmental subdivision of hindbrain7.98e-0712
hindbrain7.98e-0712
presumptive hindbrain7.98e-0712


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.