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Coexpression cluster:C1410

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Full id: C1410_Pericytes_Fibroblast_chorionic_Hair_Chondrocyte_Meningeal_Preadipocyte



Phase1 CAGE Peaks

Hg19::chr15:74466870..74466923,+p1@ISLR
Hg19::chr15:74466924..74466935,+p6@ISLR
Hg19::chr15:74467398..74467422,+p1@CU692640
Hg19::chr15:74467592..74467625,+p7@ISLR
Hg19::chr15:74467690..74467701,-p@chr15:74467690..74467701
-
Hg19::chr15:74468492..74468517,+p@chr15:74468492..74468517
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0007155cell adhesion0.0423878488166725
GO:0022610biological adhesion0.0423878488166725



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
organism subdivision7.69e-17365
dermomyotome4.69e-1570
muscle tissue9.25e-1563
musculature9.25e-1563
musculature of body9.25e-1563
somite9.32e-1583
paraxial mesoderm9.32e-1583
presomitic mesoderm9.32e-1583
presumptive segmental plate9.32e-1583
trunk paraxial mesoderm9.32e-1583
presumptive paraxial mesoderm9.32e-1583
skeletal muscle tissue2.91e-1461
striated muscle tissue2.91e-1461
myotome2.91e-1461
adult organism4.23e-14115
multilaminar epithelium3.16e-1182
multi-tissue structure5.79e-10347
multi-cellular organism1.37e-09659
tissue1.20e-08787
cell layer1.33e-08312
regional part of brain2.21e-0859
adipose tissue5.13e-0814
trunk mesenchyme7.73e-08143
epithelium8.26e-08309
neural plate1.26e-0786
presumptive neural plate1.26e-0786
neural tube2.37e-0757
neural rod2.37e-0757
future spinal cord2.37e-0757
neural keel2.37e-0757
primary circulatory organ2.43e-0727
central nervous system2.87e-0782
anatomical cluster3.36e-07286
splanchnic layer of lateral plate mesoderm3.40e-0784
heart4.43e-0724
primitive heart tube4.43e-0724
primary heart field4.43e-0724
anterior lateral plate mesoderm4.43e-0724
heart tube4.43e-0724
heart primordium4.43e-0724
cardiac mesoderm4.43e-0724
cardiogenic plate4.43e-0724
heart rudiment4.43e-0724
brain9.22e-0769
future brain9.22e-0769
neurectoderm9.99e-0790


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.