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Coexpression cluster:C4864

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Full id: C4864_Mast_CD14_Eosinophils_Monocytederived_chronic_Reticulocytes_Macrophage



Phase1 CAGE Peaks

Hg19::chrX:154033633..154033644,-p4@MPP1
Hg19::chrX:154033645..154033656,-p3@MPP1
Hg19::chrX:154033661..154033676,-p2@MPP1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Uber Anatomy
Ontology termp-valuen
hemolymphoid system1.73e-21112
lateral plate mesoderm5.83e-21216
adult organism2.72e-20115
hematopoietic system4.76e-20102
blood island4.76e-20102
immune system1.50e-19115
bone marrow6.06e-1980
bone element1.65e-1786
musculoskeletal system1.68e-15167
skeletal element9.07e-14101
skeletal system9.07e-14101
circulatory system2.25e-10113
anatomical system2.74e-10625
anatomical group4.52e-10626
cardiovascular system1.24e-09110
multi-cellular organism1.50e-09659
mesoderm1.44e-08448
mesoderm-derived structure1.44e-08448
presumptive mesoderm1.44e-08448
tissue4.32e-08787
organ1.80e-07511
tube2.65e-07194
embryo5.03e-07612
anatomical conduit5.64e-07241
embryonic structure6.52e-07605
developing anatomical structure6.52e-07605
germ layer6.55e-07604
embryonic tissue6.55e-07604
presumptive structure6.55e-07604
epiblast (generic)6.55e-07604
neural tube6.90e-0757
neural rod6.90e-0757
future spinal cord6.90e-0757
neural keel6.90e-0757
Disease
Ontology termp-valuen
myeloid leukemia8.10e-0731


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.