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MCL coexpression mm9:122

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:126602396..126602419,+p4@B4galnt1
Mm9::chr10:13685045..13685054,+p@chr10:13685045..13685054
+
Mm9::chr10:13685064..13685085,+p@chr10:13685064..13685085
+
Mm9::chr10:42580501..42580520,+p3@Scml4
Mm9::chr10:77760880..77760891,-p19@Agpat3
Mm9::chr10:77760907..77760929,-p6@Agpat3
Mm9::chr11:103206045..103206073,+p2@Gm11648
Mm9::chr11:103206079..103206126,+p1@Gm11648
Mm9::chr11:106611587..106611660,-p5@Pecam1
Mm9::chr11:106611989..106612004,+p@chr11:106611989..106612004
+
Mm9::chr11:118109821..118109885,-p1@Cyth1
Mm9::chr11:51391390..51391396,+p@chr11:51391390..51391396
+
Mm9::chr11:6289120..6289140,+p5@Zmiz2
Mm9::chr11:75150291..75150312,-p@chr11:75150291..75150312
-
Mm9::chr11:99016486..99016499,+p@chr11:99016486..99016499
+
Mm9::chr12:77187706..77187736,+p@chr12:77187706..77187736
+
Mm9::chr13:112599146..112599226,-p1@Map3k1
Mm9::chr13:24706074..24706083,+p12@Fam65b
Mm9::chr13:24706445..24706452,+p7@Fam65b
Mm9::chr13:24706457..24706472,+p3@Fam65b
Mm9::chr13:67476665..67476693,-p2@Zfp456
Mm9::chr14:57194346..57194371,+p3@Parp4
Mm9::chr14:57194374..57194383,+p4@Parp4
Mm9::chr15:5058469..5058490,-p2@Card6
Mm9::chr15:67008386..67008403,-p3@St3gal1
Mm9::chr15:88977579..88977625,-p@chr15:88977579..88977625
-
Mm9::chr15:97077389..97077435,+p2@Fam113b
Mm9::chr15:97077442..97077483,+p3@Fam113b
Mm9::chr15:97191611..97191656,+p1@Fam113b
Mm9::chr16:23224945..23224996,+p2@St6gal1
Mm9::chr17:25032405..25032430,-p2@Eme2
Mm9::chr17:25032464..25032487,+p2@Mrps34
Mm9::chr17:34324647..34324694,+p2@Tap1
Mm9::chr17:37407200..37407205,+p2@H2-M3
Mm9::chr17:37407206..37407223,+p@chr17:37407206..37407223
+
Mm9::chr17:84580558..84580579,+p@chr17:84580558..84580579
+
Mm9::chr18:32557271..32557332,+p@chr18:32557271..32557332
+
Mm9::chr18:56628862..56628868,+p7@Gramd3
Mm9::chr18:56628869..56628892,+p4@Gramd3
Mm9::chr18:56629164..56629171,+p@chr18:56629164..56629171
+
Mm9::chr18:65574650..65574662,+p@chr18:65574650..65574662
+
Mm9::chr19:25127000..25127009,+p5@Dock8
Mm9::chr19:25127026..25127031,+p8@Dock8
Mm9::chr19:29441762..29441777,-p5@5033414D02Rik
Mm9::chr19:4204194..4204207,+p@chr19:4204194..4204207
+
Mm9::chr19:4204211..4204221,+p@chr19:4204211..4204221
+
Mm9::chr1:193916421..193916500,-p1@Traf5
Mm9::chr1:52289245..52289276,-p4@Gls
Mm9::chr1:52687536..52687601,+p1@Tmem194b
Mm9::chr1:58859336..58859361,+p6@Casp8
Mm9::chr2:150493121..150493157,+p1@E130215H24Rik
Mm9::chr2:165818215..165818226,+p4@Ncoa3
Mm9::chr2:168415791..168415802,-p5@Nfatc2
Mm9::chr2:24240651..24240687,+p5@Psd4
Mm9::chr2:71975181..71975199,+p@chr2:71975181..71975199
+
Mm9::chr2:79095374..79095400,+p11@Itga4
Mm9::chr2:79096094..79096109,+p5@Itga4
Mm9::chr3:101092050..101092065,-p4@Cd2
Mm9::chr3:68930763..68930807,-p4@Kpna4
Mm9::chr4:100937461..100937483,-p@chr4:100937461..100937483
-
Mm9::chr4:105985923..105985934,+p@chr4:105985923..105985934
+
Mm9::chr4:16090758..16090772,-p3@Ripk2
Mm9::chr4:32336396..32336403,+p@chr4:32336396..32336403
+
Mm9::chr5:121161785..121161796,+p@chr5:121161785..121161796
+
Mm9::chr5:37438641..37438657,+p6@Jakmip1
Mm9::chr5:72559357..72559377,-p2@Commd8
Mm9::chr6:38305533..38305551,-p@chr6:38305533..38305551
-
Mm9::chr6:48597207..48597218,+p2@Gimap8
Mm9::chr6:48597223..48597297,+p1@Gimap8
Mm9::chr6:48601771..48601774,+p@chr6:48601771..48601774
+
Mm9::chr6:48658205..48658251,-p1@Gimap6
Mm9::chr6:48688951..48688965,-p@chr6:48688951..48688965
-
Mm9::chr6:48689038..48689095,+p1@Gimap1
Mm9::chr6:48690612..48690631,-p1@ENSMUST00000155906
Mm9::chr6:48696168..48696179,+p4@Gimap5
Mm9::chr6:48696187..48696211,+p2@Gimap5
Mm9::chr7:133428921..133428932,-p@chr7:133428921..133428932
-
Mm9::chr7:90809588..90809600,-p@chr7:90809588..90809600
-
Mm9::chr8:109207033..109207054,+p2@Tmco7
Mm9::chr8:13677775..13677827,+p@chr8:13677775..13677827
+
Mm9::chr8:23816979..23817052,-p1@Ikbkb
Mm9::chr8:3353417..3353468,+p1@A430078G23Rik
Mm9::chr8:3353499..3353525,+p3@A430078G23Rik
Mm9::chr8:47237988..47238002,+p1@ENSMUST00000147206
Mm9::chr8:90812927..90812975,+p1@Adcy7
Mm9::chr8:96958042..96958070,-p1@ENSMUST00000098492
Mm9::chr8:96958159..96958197,-p1@ENSMUST00000057009
Mm9::chr8:96958243..96958254,+p@chr8:96958243..96958254
+
Mm9::chr8:96958278..96958303,+p@chr8:96958278..96958303
+
Mm9::chr9:107453750..107453771,+p7@Rassf1
Mm9::chr9:107985661..107985701,-p4@Rnf123
Mm9::chr9:108953667..108953733,+p1@Shisa5
Mm9::chr9:108955342..108955378,+p4@Shisa5
Mm9::chr9:108955381..108955394,+p10@Shisa5
Mm9::chr9:108955396..108955417,+p7@Shisa5
Mm9::chr9:21936050..21936064,-p@chr9:21936050..21936064
-
Mm9::chrX:104344919..104344944,+p1@A630033H20Rik
Mm9::chrX:156146546..156146574,+p4@Sh3kbp1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0030173integral to Golgi membrane0.00374337247082646
GO:0031228intrinsic to Golgi membrane0.00374337247082646
GO:0031301integral to organelle membrane0.0204991446629905
GO:0031300intrinsic to organelle membrane0.0204991446629905
GO:0000139Golgi membrane0.0268998940548663
GO:0051092activation of NF-kappaB transcription factor0.0268998940548663
GO:0043413biopolymer glycosylation0.0341803125074024
GO:0051091positive regulation of transcription factor activity0.0371653898988394
GO:0008373sialyltransferase activity0.0371653898988394



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
lymphoid lineage restricted progenitor cell1.36e-1312
T cell1.70e-1211
pro-T cell1.70e-1211
lymphocyte3.21e-1213
common lymphoid progenitor3.21e-1213
mature alpha-beta T cell4.66e-119
alpha-beta T cell4.66e-119
immature T cell4.66e-119
mature T cell4.66e-119
immature alpha-beta T cell4.66e-119
hematopoietic lineage restricted progenitor cell7.70e-1125
CD4-positive, alpha-beta T cell6.35e-108
nucleate cell3.68e-0916
hematopoietic cell4.00e-0932
hematopoietic oligopotent progenitor cell4.00e-0932
hematopoietic stem cell4.00e-0932
angioblastic mesenchymal cell4.00e-0932
hematopoietic multipotent progenitor cell4.00e-0932
leukocyte2.17e-0817
nongranular leukocyte2.17e-0817
thymocyte1.08e-076
double negative thymocyte1.08e-076
naive T cell1.08e-076
double-positive, alpha-beta thymocyte1.08e-076
CD4-positive, alpha-beta thymocyte1.08e-076
naive thymus-derived CD4-positive, alpha-beta T cell1.08e-076
DN4 thymocyte1.08e-076
DN1 thymic pro-T cell1.08e-076
DN2 thymocyte1.08e-076
DN3 thymocyte1.08e-076
immature single positive thymocyte1.08e-076
early T lineage precursor1.08e-076
mature CD4 single-positive thymocyte1.08e-076
resting double-positive thymocyte1.08e-076
double-positive blast1.08e-076
CD69-positive double-positive thymocyte1.08e-076
CD69-positive, CD4-positive single-positive thymocyte1.08e-076
CD4-positive, CD8-intermediate double-positive thymocyte1.08e-076
CD24-positive, CD4 single-positive thymocyte1.08e-076

Uber Anatomy
Ontology termp-valuen
hemopoietic organ4.25e-2029
immune organ4.25e-2029
hemolymphoid system6.17e-1948
immune system6.17e-1948
mixed endoderm/mesoderm-derived structure1.03e-1835
gland of gut2.04e-1724
thymus1.37e-1623
neck1.37e-1623
respiratory system epithelium1.37e-1623
hemolymphoid system gland1.37e-1623
pharyngeal epithelium1.37e-1623
thymic region1.37e-1623
pharyngeal gland1.37e-1623
entire pharyngeal arch endoderm1.37e-1623
thymus primordium1.37e-1623
early pharyngeal endoderm1.37e-1623
hematopoietic system1.59e-1645
blood island1.59e-1645
pharynx1.35e-1524
upper respiratory tract1.35e-1524
chordate pharynx1.35e-1524
pharyngeal arch system1.35e-1524
pharyngeal region of foregut1.35e-1524
respiratory system2.11e-1542
respiratory tract1.19e-1441
segment of respiratory tract4.58e-1327
foregut1.02e-1080
organ segment1.55e-0935
digestive system2.54e-09116
digestive tract2.54e-09116
primitive gut2.54e-09116
craniocervical region3.50e-0936
lateral plate mesoderm5.63e-0987
endoderm-derived structure6.32e-09118
endoderm6.32e-09118
presumptive endoderm6.32e-09118
subdivision of digestive tract1.93e-08114
endo-epithelium2.11e-0769


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.751602
MA0004.10.309564
MA0006.10.143595
MA0007.10.157554
MA0009.10.276069
MA0014.10.0517667
MA0017.10.121784
MA0019.10.0269188
MA0024.10.49814
MA0025.10.19779
MA0027.11.43681
MA0028.10.0514316
MA0029.10.209251
MA0030.10.0595096
MA0031.10.182492
MA0038.10.139545
MA0040.10.289796
MA0041.10.154731
MA0042.10.22711
MA0043.10.123091
MA0046.10.0953474
MA0048.11.29057
MA0050.15.23346
MA0051.13.91327
MA0052.10.298791
MA0055.12.26359
MA0056.10
MA0057.10.104675
MA0058.10.330565
MA0059.10.369814
MA0060.10.240386
MA0061.12.60284
MA0063.10
MA0066.10.128888
MA0067.10.742439
MA0068.11.72377
MA0069.10.0890599
MA0070.10.602633
MA0071.10.130428
MA0072.10.27905
MA0073.12.94657
MA0074.10.372515
MA0076.10.00552051
MA0077.10.0734884
MA0078.10.362191
MA0081.11.39135
MA0083.10.122707
MA0084.10.522943
MA0087.10.102695
MA0088.10.0782412
MA0089.10
MA0090.10.130524
MA0091.10.103785
MA0092.10.548649
MA0093.10.408812
MA0095.10
MA0098.10
MA0100.10.088341
MA0101.11.57689
MA0103.10.864477
MA0105.10.547414
MA0106.10.377481
MA0107.12.89511
MA0108.20.129396
MA0109.10
MA0111.10.263016
MA0113.10.3234
MA0114.10.167922
MA0115.10.124455
MA0116.10.334355
MA0117.10.3532
MA0119.11.90772
MA0122.10.758482
MA0124.10.660364
MA0125.10.551321
MA0130.10
MA0131.10.497478
MA0132.10
MA0133.10
MA0135.10.436212
MA0136.12.50889
MA0139.11.36752
MA0140.10.192205
MA0141.10.0505771
MA0142.11.05798
MA0143.10.179907
MA0144.12.61588
MA0145.11.47191
MA0146.10.470655
MA0147.10.0437857
MA0148.10.106905
MA0149.10.0404853
MA0062.25.3235
MA0035.20.198945
MA0039.20.898538
MA0138.20.77244
MA0002.21.63753
MA0137.21.50503
MA0104.20.079835
MA0047.20.138787
MA0112.20.257199
MA0065.20.0335858
MA0150.10.0307853
MA0151.10
MA0152.10.0505735
MA0153.10.150162
MA0154.10.643818
MA0155.10.169351
MA0156.15.3133
MA0157.10.143409
MA0158.10
MA0159.10.0956886
MA0160.10.0137176
MA0161.10
MA0162.10.528871
MA0163.10.651541
MA0164.10.938468
MA0080.29.28886
MA0018.20.123332
MA0099.20.100425
MA0079.20.184459
MA0102.20.567661
MA0258.10.00401815
MA0259.10.016524
MA0442.10