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MCL coexpression mm9:729

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Phase1 CAGE Peaks

 Short description
Mm9::chr13:83868737..83868740,-p@chr13:83868737..83868740
-
Mm9::chr14:65206197..65206209,+p@chr14:65206197..65206209
+
Mm9::chr14:65206221..65206271,+p@chr14:65206221..65206271
+
Mm9::chr14:65206315..65206326,+p@chr14:65206315..65206326
+
Mm9::chr14:65207382..65207396,+p@chr14:65207382..65207396
+
Mm9::chr14:65209215..65209226,+p6@Mir124a-1
Mm9::chr14:65209566..65209569,+p2@Mir124a-1
Mm9::chr17:66728233..66728248,-p4@1110012J17Rik
Mm9::chr2:77655725..77655739,-p15@Zfp385b
Mm9::chr4:131604903..131604927,-p5@Epb4.1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0030507spectrin binding0.00986112250224788
GO:0030866cortical actin cytoskeleton organization and biogenesis0.0164316022299325
GO:0030865cortical cytoskeleton organization and biogenesis0.0164316022299325
GO:0008360regulation of cell shape0.0385751166497428
GO:0022603regulation of anatomical structure morphogenesis0.0385751166497428
GO:0022604regulation of cell morphogenesis0.0385751166497428
GO:0019898extrinsic to membrane0.0485120407029977



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neurectoderm1.64e-4064
neural plate1.64e-4064
presumptive neural plate1.64e-4064
ecto-epithelium2.83e-3473
ectoderm-derived structure5.36e-3295
ectoderm5.36e-3295
presumptive ectoderm5.36e-3295
pre-chordal neural plate9.74e-3249
regional part of nervous system4.34e-3154
central nervous system4.70e-3073
neural tube2.75e-2952
neural rod2.75e-2952
future spinal cord2.75e-2952
neural keel2.75e-2952
nervous system1.00e-2875
brain5.81e-2647
future brain5.81e-2647
gray matter1.39e-2534
regional part of brain6.30e-2546
structure with developmental contribution from neural crest9.27e-2592
anterior neural tube9.15e-2340
brain grey matter5.01e-2229
regional part of telencephalon5.01e-2229
telencephalon5.01e-2229
regional part of forebrain6.44e-2239
forebrain6.44e-2239
future forebrain6.44e-2239
cerebral cortex3.86e-1521
cerebral hemisphere3.86e-1521
pallium3.86e-1521
regional part of cerebral cortex6.48e-1217
eye7.64e-109
camera-type eye7.64e-109
simple eye7.64e-109
immature eye7.64e-109
ocular region7.64e-109
visual system7.64e-109
face7.64e-109
optic cup7.64e-109
optic vesicle7.64e-109
eye primordium7.64e-109
occipital lobe7.68e-1010
visual cortex7.68e-1010
neocortex7.68e-1010
basal ganglion4.49e-088
nuclear complex of neuraxis4.49e-088
aggregate regional part of brain4.49e-088
collection of basal ganglia4.49e-088
cerebral subcortex4.49e-088
sense organ6.25e-0812
sensory system6.25e-0812
entire sense organ system6.25e-0812
subdivision of head1.60e-0711
head4.42e-0713
ectodermal placode4.42e-0713
posterior neural tube5.86e-0712
chordal neural plate5.86e-0712


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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