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Coexpression cluster:C1847: Difference between revisions

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|ontology_enrichment_celltype=
|ontology_enrichment_celltype=
|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0001049!4.65e-25!57;UBERON:0005068!4.65e-25!57;UBERON:0006241!4.65e-25!57;UBERON:0007135!4.65e-25!57;UBERON:0007023!2.01e-24!115;UBERON:0001017!1.46e-22!82;UBERON:0005743!2.99e-21!86;UBERON:0000955!3.22e-21!69;UBERON:0006238!3.22e-21!69;UBERON:0002780!4.75e-21!41;UBERON:0001890!4.75e-21!41;UBERON:0006240!4.75e-21!41;UBERON:0000073!1.61e-20!94;UBERON:0001016!1.61e-20!94;UBERON:0002616!1.85e-20!59;UBERON:0003080!4.36e-20!42;UBERON:0003075!4.49e-19!86;UBERON:0007284!4.49e-19!86;UBERON:0002020!5.32e-19!34;UBERON:0003528!5.32e-19!34;UBERON:0001893!8.58e-19!34;UBERON:0002791!3.54e-18!33;UBERON:0002346!5.48e-18!90;UBERON:0001869!5.70e-18!32;UBERON:0000956!1.42e-13!25;UBERON:0000203!1.42e-13!25;UBERON:0000033!2.61e-13!123;UBERON:0000153!2.99e-13!129;UBERON:0007811!2.99e-13!129;UBERON:0003056!8.87e-13!61;UBERON:0004121!9.87e-13!169;UBERON:0000924!2.74e-12!173;UBERON:0006601!2.74e-12!173;UBERON:0002619!5.45e-12!22;UBERON:0001950!1.15e-10!20;UBERON:0004111!3.42e-10!241;UBERON:0000025!9.18e-09!194;UBERON:0000477!3.08e-08!286;UBERON:0000468!1.04e-07!659;UBERON:0000062!4.26e-07!511;UBERON:0002308!5.89e-07!9;UBERON:0000125!5.89e-07!9;UBERON:0000467!6.69e-07!625;UBERON:0000480!8.92e-07!626
|ontology_enrichment_uberon=UBERON:0001049!2.49e-32!56;UBERON:0005068!2.49e-32!56;UBERON:0006241!2.49e-32!56;UBERON:0007135!2.49e-32!56;UBERON:0000073!5.01e-31!53;UBERON:0002616!5.01e-31!53;UBERON:0007023!6.07e-27!114;UBERON:0001017!1.95e-26!81;UBERON:0000955!5.58e-26!68;UBERON:0006238!5.58e-26!68;UBERON:0001016!8.83e-26!89;UBERON:0002780!9.40e-26!41;UBERON:0001890!9.40e-26!41;UBERON:0003080!9.40e-26!41;UBERON:0006240!9.40e-26!41;UBERON:0003528!2.07e-24!34;UBERON:0002020!2.07e-24!34;UBERON:0001893!5.51e-24!34;UBERON:0002791!3.18e-22!32;UBERON:0001869!3.31e-22!32;UBERON:0003075!2.88e-20!82;UBERON:0007284!2.88e-20!82;UBERON:0000956!6.65e-19!25;UBERON:0000203!6.65e-19!25;UBERON:0002346!1.12e-18!86;UBERON:0002619!3.53e-16!22;UBERON:0001950!5.02e-16!20;UBERON:0003056!3.26e-15!61;UBERON:0010314!3.56e-15!132;UBERON:0010371!7.48e-14!104;UBERON:0011216!9.39e-14!223;UBERON:0004121!8.00e-13!171;UBERON:0000924!8.00e-13!171;UBERON:0006601!8.00e-13!171;UBERON:0004111!9.47e-12!240;UBERON:0000477!2.46e-11!373;UBERON:0000025!1.43e-10!192;UBERON:0000200!3.04e-08!6;UBERON:0002298!4.92e-08!6;UBERON:0003076!8.56e-08!15;UBERON:0003057!8.56e-08!15;UBERON:0001872!1.07e-07!5;UBERON:0000481!5.36e-07!342;UBERON:0000125!5.95e-07!9;UBERON:0002308!5.95e-07!9
|tf_chipseq_enrich=RAD21#5885;4:8.28402711636506:0.000401162263912245:0.00386789011085035!TRIM28#10155;5:18.5905250452625:4.49912775886781e-07:2.13680947707319e-05
|tf_chipseq_enrich=RAD21#5885;4:8.28402711636506:0.000401162263912245:0.00386789011085035!TRIM28#10155;5:18.5905250452625:4.49912775886781e-07:2.13680947707319e-05
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}}
}}

Revision as of 11:45, 19 October 2012


Full id: C1847_gastrointestinal_cerebellum_parietal_middle_salivary_acute_Neurons



Phase1 CAGE Peaks

Hg19::chr1:208322827..208322863,-p@chr1:208322827..208322863
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Hg19::chr1:208322943..208322955,-p@chr1:208322943..208322955
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Hg19::chr1:208322971..208322987,-p@chr1:208322971..208322987
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Hg19::chr1:208322991..208323006,-p@chr1:208322991..208323006
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Hg19::chr1:208323145..208323153,-p@chr1:208323145..208323153
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube2.49e-3256
neural rod2.49e-3256
future spinal cord2.49e-3256
neural keel2.49e-3256
regional part of nervous system5.01e-3153
regional part of brain5.01e-3153
adult organism6.07e-27114
central nervous system1.95e-2681
brain5.58e-2668
future brain5.58e-2668
nervous system8.83e-2689
regional part of forebrain9.40e-2641
forebrain9.40e-2641
anterior neural tube9.40e-2641
future forebrain9.40e-2641
brain grey matter2.07e-2434
gray matter2.07e-2434
telencephalon5.51e-2434
regional part of telencephalon3.18e-2232
cerebral hemisphere3.31e-2232
neural plate2.88e-2082
presumptive neural plate2.88e-2082
cerebral cortex6.65e-1925
pallium6.65e-1925
neurectoderm1.12e-1886
regional part of cerebral cortex3.53e-1622
neocortex5.02e-1620
pre-chordal neural plate3.26e-1561
structure with developmental contribution from neural crest3.56e-15132
ecto-epithelium7.48e-14104
organ system subdivision9.39e-14223
ectoderm-derived structure8.00e-13171
ectoderm8.00e-13171
presumptive ectoderm8.00e-13171
anatomical conduit9.47e-12240
anatomical cluster2.46e-11373
tube1.43e-10192
gyrus3.04e-086
brainstem4.92e-086
posterior neural tube8.56e-0815
chordal neural plate8.56e-0815
parietal lobe1.07e-075
multi-tissue structure5.36e-07342
neural nucleus5.95e-079
nucleus of brain5.95e-079


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
RAD21#588548.284027116365060.0004011622639122450.00386789011085035
TRIM28#10155518.59052504526254.49912775886781e-072.13680947707319e-05



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.