MCL coexpression mm9:218: Difference between revisions
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{{MCL_coexpression_mm9| | {{MCL_coexpression_mm9|coexpression_dpi_cluster_scores_mean=0.0519118849142325,-0.0123225700488282,0.00758352548522086,-0.00945342508054674,0.00274350783951503,-0.00138749722067173,-0.000925218690935822,0.00612907624575382,0.0319517514907863,0.0323153319934683,0.0147732051793877,0.0172231227067859,-0.00205409357017548,-0.00322613371096075,0.006237630678675,-0.00368895420669832,-0.0065641455207557,-0.00441921068312076,-0.00858175339533074,-0.0123225700488282,0.170262502541067,0.0292294904262482,0.00752916219404268,-0.0107111912394862,-0.00822253803188609,-0.00739585189093497,-0.000655015354972068,-0.00479047866584894,-0.0104336823408932,-0.0123225700488282,-0.0101481845542433,0.00835402672537415,0.0107595376574548,-0.0123225700488282,-0.0123225700488282,-0.0106529215770163,-0.00457051356093971,-0.0123225700488282,-0.0123225700488282,-0.0123225700488282,-0.0123225700488282,-0.0123225700488282,-0.0123225700488282,0.00501722208440976,0.00431471549871113,0.00998781529077918,0.0390310619463674,0.0204623479312692,0.0350319162885139,0.0290204990082668,0.0217503089061334,0.0217318259896243,-0.0123225700488282,0.000224737744032751,0.00592520869628192,0.0237949088442323,0.0221998826972514,0.00306660570754539,0.0632589215075726,0.0560350650547652,0.0459132359650212,0.0121942504173482,0.00869531411631378,-0.00535430309580627,-0.00485742998240105,-0.00649461930648777,0.0547095744578507,0.0671103023858788,0.0145573331218511,0.00370224980526288,0.0133951593214185,0.406358111327,0.34214461821736,0.0161372935030824,0.0158852179673807,0.00945877010768408,0.403928150057757,0.450087460689481,0.533736964168942,0.043561377882409,0.0402498731848253,0.0318558751341473,0.635825562212401,0.268852696317527,0.363727260976567,0.325086026421877,0.338954697485144,0.182731679684118,0.0481639872163478,0.0751071306980716,0.0218489834075296,-0.0123225700488282,-0.00669002326935357,-0.00763664479832752,-0.00688694276542164,-0.0123225700488282,0.105948988557153,0.00543427463732199,-0.00981515056599072,0.00209454822811664,0.061719905897419,-0.0123225700488282,0.0210534911727938,-0.0123225700488282,-0.00342226470619323,-0.0123225700488282,-0.000294809043204197,0.0377740805716758,0.00543668238912492,0.0477240138337788,0.0182607153792841,0.0247383801475024,0.028639616694313,0.0382142141730893,0.0313015651528257,0.0145673807041414,0.0086620120354233,0.0130781296565153,-0.0123225700488282,0.00670364296926707,-0.00365664101104063,-0.00373807157999452,0.0333734819750285,0.309651168226181,0.267680417216841,0.00404955842638247,0.00212434767973326,-0.00211789106218597,-0.00786051420345602,0.532714887476177,0.346024385282889,0.031561902418492,0.157154625087936,0.119026360224548,0.487718083873221,0.34571512610292,0.00692048942604504,0.00821178625205804,0.0141800907632591,0.128213854816199,0.0161403300582388,0.0312527027503797,0.0366788356454738,0.0230831756670716,0.0441777816051461,0.0395492151858571,0.040694561375664,0.189693913061663,0.00190380522115312,0.00377338945252973,0.00849587336412199,0.00745546764881503,0.0107248932087922,0.00396548988367811,0.0083586026258101,0.00393182272740596,-0.0123225700488282,-0.00781443441707349,-0.00960706201070944,0.00705427922186156,0.00877622348352338,0.00419862259488567,0.00790822016957406,0.00507420967058349,0.00741089655163332,0.00895449371603916,-0.000505510582146225,0.00179291476956944,0.00340626518448959,0.00528324576581462,0.00387859768999407,0.00298151628942899,0.0133743367770936,0.011452936699465,0.130471688619895,0.0341514561096339,0.00929062947304775,0.00372364450568711,0.00689584325646561,0.00361328696432023,0.0164011307990539,0.0182623334146182,0.0198910886581654,0.0137290664988792,0.00454276360089213,0.00852958291253023,0.014253968447103,0.0134455270963137,0.00587091232863537,-0.0123225700488282,-0.0020481856754411,0.00890164169979714,0.00647519008080666,0.00994275549008219,-0.00412798793771479,0.0119285691717995,0.0117355414512295,0.0101877542412093,0.01152885657964,0.00723074442289272,0.01081720096758,0.0159897393944822,-0.00726782142927052,-0.000934547392919028,-0.00452915845672431,-0.00571602995960938,0.000144166217000922,-0.00804876946830782,-0.000464960780022792,-0.00408656557422053,-0.00166174181571037,0.000331633753953833,0.00702628305669119,0.0057986804323867,-0.00220064478186425,-0.00788301952859127,-0.00585580036801739,-0.00804811613750707,0.00419459650661142,0.00495193633251821,1.65031716137499e-05,-0.00300915605092943,0.00509601914664063,0.00114608475263662,0.00239312833737627,-0.00105889590739761,0.00535992732365612,0.00392480466372069,0.00774011056799675,-0.000163251183874693,0.0120258004970744,0.00782837549212136,-0.0123225700488282,-0.00181659018968844,0.00382808257364938,-0.00438538416890742,1.0738351852038,0.975713320453807,0.0042058702858441,-0.00299619434926161,0.0332935663995082,0.0391880929662639,0.0481697054405234,0.0293024923581356,0.0506567835571535,0.0386446142736266,0.031396477197948,0.0346751119418698,0.0284547910196631,0.170614941590006,0.0189985825784442,0.00263080654851281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transmembrane transporter activity;0.0225085773427904;63993,20538!GO:0015370;solute:sodium symporter activity;0.0225085773427904;63993,20538!GO:0015294;solute:cation symporter activity;0.0225085773427904;63993,20538!GO:0015075;ion transmembrane transporter activity;0.0225085773427904;74268,63993,14654,20538!GO:0015837;amine transport;0.0225085773427904;63993,20538!GO:0008292;acetylcholine biosynthetic process;0.0225085773427904;63993!GO:0042737;drug catabolic process;0.0225085773427904;18125!GO:0005307;choline:sodium symporter activity;0.0225085773427904;63993!GO:0042738;exogenous drug catabolic process;0.0225085773427904;18125!GO:0050660;FAD binding;0.0225085773427904;74051,18125!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.0225085773427904;380684,17755!GO:0006811;ion transport;0.0225085773427904;74051,63993,18125,14654!GO:0022891;substrate-specific transmembrane transporter activity;0.0225085773427904;74268,63993,14654,20538!GO:0044271;nitrogen compound biosynthetic process;0.0225085773427904;63993,18125!GO:0051926;negative regulation of calcium ion transport;0.0225085773427904;18125!GO:0015871;choline transport;0.0225085773427904;63993!GO:0043576;regulation of respiratory gaseous exchange;0.0225085773427904;14654!GO:0060012;synaptic transmission, glycinergic;0.0225085773427904;14654!GO:0008291;acetylcholine metabolic process;0.0225085773427904;63993!GO:0015220;choline transmembrane transporter activity;0.0225085773427904;63993!GO:0022857;transmembrane transporter activity;0.0225085773427904;74268,63993,14654,20538!GO:0006810;transport;0.0225085773427904;74011,74051,63993,18125,14654,20538!GO:0030001;metal ion transport;0.0225085773427904;74051,63993,18125!GO:0051234;establishment of localization;0.0225085773427904;74011,74051,63993,18125,14654,20538!GO:0002087;neurological control of breathing;0.0225085773427904;14654!GO:0004517;nitric-oxide synthase activity;0.0225085773427904;18125!GO:0043267;negative regulation of potassium ion transport;0.0225085773427904;18125!GO:0060081;membrane hyperpolarization;0.0225085773427904;14654!GO:0045110;intermediate filament bundle assembly;0.0225085773427904;380684!GO:0060080;regulation of inhibitory postsynaptic membrane potential;0.0225085773427904;14654!GO:0015844;monoamine transport;0.0225085773427904;20538!GO:0022892;substrate-specific transporter activity;0.0225707551282698;74268,63993,14654,20538!GO:0006814;sodium ion transport;0.0225707551282698;63993,18125!GO:0050662;coenzyme binding;0.0225707551282698;74051,18125!GO:0002028;regulation of sodium ion transport;0.0225707551282698;18125!GO:0016594;glycine binding;0.0225707551282698;14654!GO:0016934;extracellular-glycine-gated chloride channel activity;0.0225707551282698;14654!GO:0043271;negative regulation of ion transport;0.0225707551282698;18125!GO:0016933;extracellular-glycine-gated ion channel activity;0.0225707551282698;14654!GO:0008504;monoamine transmembrane transporter activity;0.0225707551282698;20538!GO:0042439;ethanolamine and derivative metabolic process;0.0225707551282698;63993!GO:0005624;membrane fraction;0.0225707551282698;74051,74268,14654!GO:0008324;cation transmembrane transporter activity;0.0225707551282698;74268,63993,20538!GO:0006812;cation transport;0.0225707551282698;74051,63993,18125!GO:0043266;regulation of potassium ion transport;0.0225707551282698;18125!GO:0051346;negative regulation of hydrolase activity;0.0225707551282698;18125!GO:0003016;respiratory system process;0.0225707551282698;14654!GO:0060013;righting reflex;0.0225707551282698;14654!GO:0006893;Golgi to plasma membrane transport;0.0225707551282698;74051!GO:0017144;drug metabolic process;0.0225707551282698;18125!GO:0015293;symporter activity;0.0225707551282698;63993,20538!GO:0015674;di-, tri-valent inorganic cation transport;0.0225707551282698;74051,18125!GO:0000267;cell fraction;0.0241222418234328;74051,74268,14654!GO:0051179;localization;0.0241222418234328;74011,74051,63993,18125,14654,20538!GO:0050884;neuromuscular process controlling posture;0.0248976936058924;14654!GO:0005883;neurofilament;0.0248976936058924;380684!GO:0005519;cytoskeletal regulatory protein binding;0.0280372293627797;17755!GO:0051924;regulation of calcium ion transport;0.0280372293627797;18125!GO:0005886;plasma membrane;0.0299662575020012;74051,63993,18125,14654,20538!GO:0048037;cofactor binding;0.0299662575020012;74051,18125!GO:0060004;reflex;0.0299662575020012;14654!GO:0016597;amino acid binding;0.0299662575020012;14654!GO:0045045;secretory pathway;0.0302828536927784;74051,14654!GO:0007017;microtubule-based process;0.0302828536927784;380684,17755!GO:0015291;secondary active transmembrane transporter activity;0.0302828536927784;63993,20538!GO:0001578;microtubule bundle formation;0.0302828536927784;17755!GO:0060053;neurofilament cytoskeleton;0.0302828536927784;380684!GO:0060052;neurofilament cytoskeleton organization and biogenesis;0.0302828536927784;380684!GO:0045109;intermediate filament organization;0.0302828536927784;380684!GO:0006892;post-Golgi vesicle-mediated transport;0.0322092060227591;74051!GO:0007340;acrosome reaction;0.0322092060227591;14654!GO:0010181;FMN binding;0.0322092060227591;18125!GO:0007268;synaptic transmission;0.0322092060227591;63993,14654!GO:0050661;NADP binding;0.0344907557195294;18125!GO:0032940;secretion by cell;0.03523425512745;74051,14654!GO:0048265;response to pain;0.03523425512745;20538!GO:0043269;regulation of ion transport;0.03523425512745;18125!GO:0001964;startle response;0.03523425512745;14654!GO:0060078;regulation of postsynaptic membrane potential;0.03523425512745;14654!GO:0007274;neuromuscular synaptic transmission;0.036319963501225;63993!GO:0007271;synaptic transmission, cholinergic;0.036319963501225;63993!GO:0004293;tissue kallikrein activity;0.036319963501225;16612!GO:0042136;neurotransmitter biosynthetic process;0.036319963501225;63993!GO:0019226;transmission of nerve impulse;0.0387874874124148;63993,14654!GO:0043176;amine binding;0.0408969489234937;14654!GO:0045104;intermediate filament cytoskeleton organization and biogenesis;0.0447428136131082;380684!GO:0006809;nitric oxide biosynthetic process;0.0447428136131082;18125!GO:0046209;nitric oxide metabolic process;0.0447428136131082;18125!GO:0051051;negative regulation of transport;0.0463080275310763;18125!GO:0005328;neurotransmitter:sodium symporter activity;0.0463080275310763;20538!GO:0046903;secretion;0.0468846965000058;74051,14654!GO:0007585;respiratory gaseous exchange;0.0478036782542486;14654!GO:0017156;calcium ion-dependent exocytosis;0.0487159519888813;14654!GO:0005326;neurotransmitter transporter activity;0.0487159519888813;20538!GO:0045103;intermediate filament-based process;0.0487159519888813;380684!|ontology_enrichment_celltype=CL:0000117!9.33e-15!23;CL:0000337!9.33e-15!23;CL:0002610!1.20e-10!3;CL:0002614!2.15e-10!3;CL:0000540!1.20e-09!33;CL:0000047!1.20e-09!33;CL:0000031!1.20e-09!33;CL:0000404!1.20e-09!33;CL:0002612!1.67e-09!3;CL:0000393!7.60e-08!39;CL:0000211!7.60e-08!39;CL:0002611!2.42e-07!2;CL:0002319!6.31e-07!43|ontology_enrichment_disease=|ontology_enrichment_uberon=UBERON:0003076!5.07e-25!12;UBERON:0003057!5.07e-25!12;UBERON:0000073!4.02e-22!54;UBERON:0001017!6.61e-19!73;UBERON:0001049!1.84e-18!52;UBERON:0005068!1.84e-18!52;UBERON:0006241!1.84e-18!52;UBERON:0007135!1.84e-18!52;UBERON:0002240!1.95e-18!6;UBERON:0005174!1.95e-18!6;UBERON:0001137!1.95e-18!6;UBERON:0001016!2.80e-18!75;UBERON:0002346!8.78e-18!64;UBERON:0003075!8.78e-18!64;UBERON:0007284!8.78e-18!64;UBERON:0004121!2.19e-16!95;UBERON:0000924!2.19e-16!95;UBERON:0006601!2.19e-16!95;UBERON:0001948!3.28e-15!5;UBERON:0002315!3.28e-15!5;UBERON:0010371!4.64e-15!73;UBERON:0002950!1.69e-13!4;UBERON:0001891!1.69e-13!4;UBERON:0009616!1.69e-13!4;UBERON:0010286!1.69e-13!4;UBERON:0010314!4.65e-11!92;UBERON:0004684!1.20e-10!3;UBERON:0002275!1.20e-10!3;UBERON:0000955!1.39e-10!47;UBERON:0006238!1.39e-10!47;UBERON:0002038!2.15e-10!3;UBERON:0009663!2.15e-10!3;UBERON:0009661!2.15e-10!3;UBERON:0000125!2.15e-10!3;UBERON:0002308!2.15e-10!3;UBERON:0002257!1.67e-09!3;UBERON:0002616!2.59e-09!46;UBERON:0002020!5.16e-09!34;UBERON:0004733!5.42e-09!6;UBERON:0004732!5.42e-09!6;UBERON:0002028!5.42e-09!6;UBERON:0007277!5.42e-09!6;UBERON:0001896!5.09e-08!2;UBERON:0002298!5.09e-08!2;UBERON:0005290!5.09e-08!2;UBERON:0010096!5.09e-08!2;UBERON:0002256!2.42e-07!2|tfbs_overrepresentation_for_novel_motifs=0.915439,0.303305,0.113995,0.395369,0.672643,0.18995,1.51905,0.31767,1.02279,0.554197,0.0681347,0.0813393,0.318423,0.307698,0.138611,0,0.199777,0.639733,1.42372,1.30813,0.417619,0.50775,0.0917729,0.0415333,0.287488,0.698503,0.577092,0.805344,0.345941,0.0745327,0.0532925,0.268728,1.23133,0.900361,0.139191,0.104267,0.00622713,0.576216,0.316009,0.128325,0.241128,0.202487,0.311366,1.8302,0.142647,1.03624,0.460501,0.49594,0.419658,0.352666,0.188647,0.118842,0.894307,0.37598,0.389905,0.0955072,0.924041,0.262717,0.223586,0.648212,0.254508,0.391246,0.827028,0.181599,0.677631,0.207411,0.503044,0.81757,0.251228,0.681742,0.462236,0.101627,0.00540504,1.07082,0.333737,0.442831,1.16108,0.144582,0.242532,0.427988,0.744168,0.60631,1.27012,0.462837,0.86994,0.000159572,0.312868,0.142392,0.153906,0.971002,0.563419,0.87843,0.277951,0.26093,0.024231,5.33689,0.180874,0.279988,0.151219,0.100436,0.211873,0.268528,0.950683,0.189022,0.551954,0.0549469,0.227389,0.062665,0.231363,0.0197211,0.0319262,2.56035,1.03487,0.246517,0.569603,0.11302,0.0911704,0.711161,0.200617,0.204936,0.421465,0.168774,1.70017,0.870185,0.617553,0.245094,2.76613,0.273057,1.25318,0.267005,0.348935,0.381713,0.476627,0.102,1.43728,0.0117117,0.94787,1.67275,0.54549,1.3282,0.940622,0.507078,0.112176,0.757844,0.542134,1.66775,0.152874,1.28935,0.145625,0.0430736,0.247836,0.000123381,0.983772,0.932048,0.332921,0.443629,0.119365,0.153349,1.75624,0.333317,0.553783,0.325224,0.245404,0.555778,0.537143,0.323433,0.852549,0.0806543,0.233166|tfbs_overrepresentation_jaspar=MA0003.1;0.109885,MA0004.1;0.0463278,MA0006.1;0.471673,MA0007.1;0.161303,MA0009.1;0.28789,MA0014.1;0.0744222,MA0017.1;0.331109,MA0019.1;0.165823,MA0024.1;0.256408,MA0025.1;0.472823,MA0027.1;1.82121,MA0028.1;0.145873,MA0029.1;0.241245,MA0030.1;0.245792,MA0031.1;0.221516,MA0038.1;0.105238,MA0040.1;0.805237,MA0041.1;0.0256044,MA0042.1;0.243023,MA0043.1;0.361422,MA0046.1;0.314603,MA0048.1;1.00909,MA0050.1;0.0596944,MA0051.1;0.354431,MA0052.1;0.303096,MA0055.1;0.206037,MA0056.1;0,MA0057.1;0.147954,MA0058.1;0.0213244,MA0059.1;0.0239063,MA0060.1;0.864705,MA0061.1;0.00471153,MA0063.1;0,MA0066.1;0.0999207,MA0067.1;0.568484,MA0068.1;2.39708,MA0069.1;0.303349,MA0070.1;0.29615,MA0071.1;0.0593865,MA0072.1;0.289901,MA0073.1;4.33418,MA0074.1;1.48852,MA0076.1;0.192105,MA0077.1;0.274126,MA0078.1;0.79512,MA0081.1;0.12094,MA0083.1;0.360799,MA0084.1;0.868194,MA0087.1;0.873394,MA0088.1;1.33682,MA0089.1;0,MA0090.1;0.333785,MA0091.1;0.740061,MA0092.1;0.14376,MA0093.1;0.0119855,MA0095.1;0,MA0098.1;0,MA0100.1;0.269978,MA0101.1;0.0258982,MA0103.1;0.180657,MA0105.1;0.00429974,MA0106.1;0.40952,MA0107.1;0.0138193,MA0108.2;0.531039,MA0109.1;0,MA0111.1;0.359123,MA0113.1;0.371139,MA0114.1;0.17479,MA0115.1;0.363622,MA0116.1;0.273529,MA0117.1;0.33849,MA0119.1;0.26679,MA0122.1;0.353887,MA0124.1;0.522168,MA0125.1;0.459209,MA0130.1;0,MA0131.1;0.163115,MA0132.1;0,MA0133.1;0,MA0135.1;0.390343,MA0136.1;0.308328,MA0139.1;0.0103686,MA0140.1;0.0784504,MA0141.1;0.40191,MA0142.1;0.211884,MA0143.1;0.124552,MA0144.1;2.16407,MA0145.1;0.318839,MA0146.1;0.0821475,MA0147.1;0.0315369,MA0148.1;0.192241,MA0149.1;0.274777,MA0062.2;0.018869,MA0035.2;0.0804587,MA0039.2;0.0152642,MA0138.2;2.8506,MA0002.2;0.486186,MA0137.2;1.33652,MA0104.2;0.013958,MA0047.2;0.341736,MA0112.2;0.0176922,MA0065.2;0.0784483,MA0150.1;1.02258,MA0151.1;0,MA0152.1;0.104915,MA0153.1;0.403751,MA0154.1;0.0491733,MA0155.1;0.730028,MA0156.1;0.0738285,MA0157.1;0.191171,MA0158.1;0,MA0159.1;0.389602,MA0160.1;0.195348,MA0161.1;0,MA0162.1;0.00102553,MA0163.1;0.146948,MA0164.1;1.57578,MA0080.2;0.173579,MA0018.2;0.320996,MA0099.2;0.915183,MA0079.2;0.597199,MA0102.2;0.917775,MA0258.1;0.00364251,MA0259.1;0.083201,MA0442.1;0}} |
Latest revision as of 14:54, 17 September 2013
Phase1 CAGE Peaks
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
GO ID | GO name | FDR corrected p-value |
---|---|---|
GO:0005275 | amine transmembrane transporter activity | 0.0225085773427904 |
GO:0015370 | solute:sodium symporter activity | 0.0225085773427904 |
GO:0015294 | solute:cation symporter activity | 0.0225085773427904 |
GO:0015075 | ion transmembrane transporter activity | 0.0225085773427904 |
GO:0015837 | amine transport | 0.0225085773427904 |
GO:0008292 | acetylcholine biosynthetic process | 0.0225085773427904 |
GO:0042737 | drug catabolic process | 0.0225085773427904 |
GO:0005307 | choline:sodium symporter activity | 0.0225085773427904 |
GO:0042738 | exogenous drug catabolic process | 0.0225085773427904 |
GO:0050660 | FAD binding | 0.0225085773427904 |
GO:0000226 | microtubule cytoskeleton organization and biogenesis | 0.0225085773427904 |
GO:0006811 | ion transport | 0.0225085773427904 |
GO:0022891 | substrate-specific transmembrane transporter activity | 0.0225085773427904 |
GO:0044271 | nitrogen compound biosynthetic process | 0.0225085773427904 |
GO:0051926 | negative regulation of calcium ion transport | 0.0225085773427904 |
GO:0015871 | choline transport | 0.0225085773427904 |
GO:0043576 | regulation of respiratory gaseous exchange | 0.0225085773427904 |
GO:0060012 | synaptic transmission, glycinergic | 0.0225085773427904 |
GO:0008291 | acetylcholine metabolic process | 0.0225085773427904 |
GO:0015220 | choline transmembrane transporter activity | 0.0225085773427904 |
GO:0022857 | transmembrane transporter activity | 0.0225085773427904 |
GO:0006810 | transport | 0.0225085773427904 |
GO:0030001 | metal ion transport | 0.0225085773427904 |
GO:0051234 | establishment of localization | 0.0225085773427904 |
GO:0002087 | neurological control of breathing | 0.0225085773427904 |
GO:0004517 | nitric-oxide synthase activity | 0.0225085773427904 |
GO:0043267 | negative regulation of potassium ion transport | 0.0225085773427904 |
GO:0060081 | membrane hyperpolarization | 0.0225085773427904 |
GO:0045110 | intermediate filament bundle assembly | 0.0225085773427904 |
GO:0060080 | regulation of inhibitory postsynaptic membrane potential | 0.0225085773427904 |
GO:0015844 | monoamine transport | 0.0225085773427904 |
GO:0022892 | substrate-specific transporter activity | 0.0225707551282698 |
GO:0006814 | sodium ion transport | 0.0225707551282698 |
GO:0050662 | coenzyme binding | 0.0225707551282698 |
GO:0002028 | regulation of sodium ion transport | 0.0225707551282698 |
GO:0016594 | glycine binding | 0.0225707551282698 |
GO:0016934 | extracellular-glycine-gated chloride channel activity | 0.0225707551282698 |
GO:0043271 | negative regulation of ion transport | 0.0225707551282698 |
GO:0016933 | extracellular-glycine-gated ion channel activity | 0.0225707551282698 |
GO:0008504 | monoamine transmembrane transporter activity | 0.0225707551282698 |
GO:0042439 | ethanolamine and derivative metabolic process | 0.0225707551282698 |
GO:0005624 | membrane fraction | 0.0225707551282698 |
GO:0008324 | cation transmembrane transporter activity | 0.0225707551282698 |
GO:0006812 | cation transport | 0.0225707551282698 |
GO:0043266 | regulation of potassium ion transport | 0.0225707551282698 |
GO:0051346 | negative regulation of hydrolase activity | 0.0225707551282698 |
GO:0003016 | respiratory system process | 0.0225707551282698 |
GO:0060013 | righting reflex | 0.0225707551282698 |
GO:0006893 | Golgi to plasma membrane transport | 0.0225707551282698 |
GO:0017144 | drug metabolic process | 0.0225707551282698 |
GO:0015293 | symporter activity | 0.0225707551282698 |
GO:0015674 | di-, tri-valent inorganic cation transport | 0.0225707551282698 |
GO:0000267 | cell fraction | 0.0241222418234328 |
GO:0051179 | localization | 0.0241222418234328 |
GO:0050884 | neuromuscular process controlling posture | 0.0248976936058924 |
GO:0005883 | neurofilament | 0.0248976936058924 |
GO:0005519 | cytoskeletal regulatory protein binding | 0.0280372293627797 |
GO:0051924 | regulation of calcium ion transport | 0.0280372293627797 |
GO:0005886 | plasma membrane | 0.0299662575020012 |
GO:0048037 | cofactor binding | 0.0299662575020012 |
GO:0060004 | reflex | 0.0299662575020012 |
GO:0016597 | amino acid binding | 0.0299662575020012 |
GO:0045045 | secretory pathway | 0.0302828536927784 |
GO:0007017 | microtubule-based process | 0.0302828536927784 |
GO:0015291 | secondary active transmembrane transporter activity | 0.0302828536927784 |
GO:0001578 | microtubule bundle formation | 0.0302828536927784 |
GO:0060053 | neurofilament cytoskeleton | 0.0302828536927784 |
GO:0060052 | neurofilament cytoskeleton organization and biogenesis | 0.0302828536927784 |
GO:0045109 | intermediate filament organization | 0.0302828536927784 |
GO:0006892 | post-Golgi vesicle-mediated transport | 0.0322092060227591 |
GO:0007340 | acrosome reaction | 0.0322092060227591 |
GO:0010181 | FMN binding | 0.0322092060227591 |
GO:0007268 | synaptic transmission | 0.0322092060227591 |
GO:0050661 | NADP binding | 0.0344907557195294 |
GO:0032940 | secretion by cell | 0.03523425512745 |
GO:0048265 | response to pain | 0.03523425512745 |
GO:0043269 | regulation of ion transport | 0.03523425512745 |
GO:0001964 | startle response | 0.03523425512745 |
GO:0060078 | regulation of postsynaptic membrane potential | 0.03523425512745 |
GO:0007274 | neuromuscular synaptic transmission | 0.036319963501225 |
GO:0007271 | synaptic transmission, cholinergic | 0.036319963501225 |
GO:0004293 | tissue kallikrein activity | 0.036319963501225 |
GO:0042136 | neurotransmitter biosynthetic process | 0.036319963501225 |
GO:0019226 | transmission of nerve impulse | 0.0387874874124148 |
GO:0043176 | amine binding | 0.0408969489234937 |
GO:0045104 | intermediate filament cytoskeleton organization and biogenesis | 0.0447428136131082 |
GO:0006809 | nitric oxide biosynthetic process | 0.0447428136131082 |
GO:0046209 | nitric oxide metabolic process | 0.0447428136131082 |
GO:0051051 | negative regulation of transport | 0.0463080275310763 |
GO:0005328 | neurotransmitter:sodium symporter activity | 0.0463080275310763 |
GO:0046903 | secretion | 0.0468846965000058 |
GO:0007585 | respiratory gaseous exchange | 0.0478036782542486 |
GO:0017156 | calcium ion-dependent exocytosis | 0.0487159519888813 |
GO:0005326 | neurotransmitter transporter activity | 0.0487159519888813 |
GO:0045103 | intermediate filament-based process | 0.0487159519888813 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
Ontology term | p-value | n |
---|---|---|
CNS neuron (sensu Vertebrata) | 9.33e-15 | 23 |
neuroblast (sensu Vertebrata) | 9.33e-15 | 23 |
raphe nuclei neuron | 1.20e-10 | 3 |
neuron of the substantia nigra | 2.15e-10 | 3 |
neuron | 1.20e-09 | 33 |
neuronal stem cell | 1.20e-09 | 33 |
neuroblast | 1.20e-09 | 33 |
electrically signaling cell | 1.20e-09 | 33 |
neuron of the ventral spinal cord | 1.67e-09 | 3 |
electrically responsive cell | 7.60e-08 | 39 |
electrically active cell | 7.60e-08 | 39 |
neuron of the dorsal spinal cord | 2.42e-07 | 2 |
neural cell | 6.31e-07 | 43 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
Motifs | -log10(p-value) |
---|---|
MA0003.1 | 0.109885 |
MA0004.1 | 0.0463278 |
MA0006.1 | 0.471673 |
MA0007.1 | 0.161303 |
MA0009.1 | 0.28789 |
MA0014.1 | 0.0744222 |
MA0017.1 | 0.331109 |
MA0019.1 | 0.165823 |
MA0024.1 | 0.256408 |
MA0025.1 | 0.472823 |
MA0027.1 | 1.82121 |
MA0028.1 | 0.145873 |
MA0029.1 | 0.241245 |
MA0030.1 | 0.245792 |
MA0031.1 | 0.221516 |
MA0038.1 | 0.105238 |
MA0040.1 | 0.805237 |
MA0041.1 | 0.0256044 |
MA0042.1 | 0.243023 |
MA0043.1 | 0.361422 |
MA0046.1 | 0.314603 |
MA0048.1 | 1.00909 |
MA0050.1 | 0.0596944 |
MA0051.1 | 0.354431 |
MA0052.1 | 0.303096 |
MA0055.1 | 0.206037 |
MA0056.1 | 0 |
MA0057.1 | 0.147954 |
MA0058.1 | 0.0213244 |
MA0059.1 | 0.0239063 |
MA0060.1 | 0.864705 |
MA0061.1 | 0.00471153 |
MA0063.1 | 0 |
MA0066.1 | 0.0999207 |
MA0067.1 | 0.568484 |
MA0068.1 | 2.39708 |
MA0069.1 | 0.303349 |
MA0070.1 | 0.29615 |
MA0071.1 | 0.0593865 |
MA0072.1 | 0.289901 |
MA0073.1 | 4.33418 |
MA0074.1 | 1.48852 |
MA0076.1 | 0.192105 |
MA0077.1 | 0.274126 |
MA0078.1 | 0.79512 |
MA0081.1 | 0.12094 |
MA0083.1 | 0.360799 |
MA0084.1 | 0.868194 |
MA0087.1 | 0.873394 |
MA0088.1 | 1.33682 |
MA0089.1 | 0 |
MA0090.1 | 0.333785 |
MA0091.1 | 0.740061 |
MA0092.1 | 0.14376 |
MA0093.1 | 0.0119855 |
MA0095.1 | 0 |
MA0098.1 | 0 |
MA0100.1 | 0.269978 |
MA0101.1 | 0.0258982 |
MA0103.1 | 0.180657 |
MA0105.1 | 0.00429974 |
MA0106.1 | 0.40952 |
MA0107.1 | 0.0138193 |
MA0108.2 | 0.531039 |
MA0109.1 | 0 |
MA0111.1 | 0.359123 |
MA0113.1 | 0.371139 |
MA0114.1 | 0.17479 |
MA0115.1 | 0.363622 |
MA0116.1 | 0.273529 |
MA0117.1 | 0.33849 |
MA0119.1 | 0.26679 |
MA0122.1 | 0.353887 |
MA0124.1 | 0.522168 |
MA0125.1 | 0.459209 |
MA0130.1 | 0 |
MA0131.1 | 0.163115 |
MA0132.1 | 0 |
MA0133.1 | 0 |
MA0135.1 | 0.390343 |
MA0136.1 | 0.308328 |
MA0139.1 | 0.0103686 |
MA0140.1 | 0.0784504 |
MA0141.1 | 0.40191 |
MA0142.1 | 0.211884 |
MA0143.1 | 0.124552 |
MA0144.1 | 2.16407 |
MA0145.1 | 0.318839 |
MA0146.1 | 0.0821475 |
MA0147.1 | 0.0315369 |
MA0148.1 | 0.192241 |
MA0149.1 | 0.274777 |
MA0062.2 | 0.018869 |
MA0035.2 | 0.0804587 |
MA0039.2 | 0.0152642 |
MA0138.2 | 2.8506 |
MA0002.2 | 0.486186 |
MA0137.2 | 1.33652 |
MA0104.2 | 0.013958 |
MA0047.2 | 0.341736 |
MA0112.2 | 0.0176922 |
MA0065.2 | 0.0784483 |
MA0150.1 | 1.02258 |
MA0151.1 | 0 |
MA0152.1 | 0.104915 |
MA0153.1 | 0.403751 |
MA0154.1 | 0.0491733 |
MA0155.1 | 0.730028 |
MA0156.1 | 0.0738285 |
MA0157.1 | 0.191171 |
MA0158.1 | 0 |
MA0159.1 | 0.389602 |
MA0160.1 | 0.195348 |
MA0161.1 | 0 |
MA0162.1 | 0.00102553 |
MA0163.1 | 0.146948 |
MA0164.1 | 1.57578 |
MA0080.2 | 0.173579 |
MA0018.2 | 0.320996 |
MA0099.2 | 0.915183 |
MA0079.2 | 0.597199 |
MA0102.2 | 0.917775 |
MA0258.1 | 0.00364251 |
MA0259.1 | 0.083201 |
MA0442.1 | 0 |