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|gostat_on_coexpression_clusters=GO:0008437!thyrotropin-releasing hormone activity!0.000618156128576475!7200$GO:0007628!adult walking behavior!0.00206052042858825!7200$GO:0009755!hormone-mediated signaling!0.00206052042858825!7200$GO:0008344!adult locomotory behavior!0.00216354645001766!7200$GO:0030534!adult behavior!0.00333804309431296!7200$GO:0005184!neuropeptide hormone activity!0.00339985870717061!7200$GO:0009725!response to hormone stimulus!0.00671140939597315!7200$GO:0007626!locomotory behavior!0.0139857824090427!7200$GO:0005179!hormone activity!0.0144648534086895!7200$GO:0005625!soluble fraction!0.0144648534086895!7200$GO:0007610!behavior!0.0165216274364985!7200$GO:0009719!response to endogenous stimulus!0.0272503826680796!7200$GO:0042221!response to chemical stimulus!0.0280072276716572!7200$GO:0007267!cell-cell signaling!0.0282585658777817!7200$GO:0000267!cell fraction!0.037171788531732!7200$GO:0005102!receptor binding!0.0400642440833628!7200
|gostat_on_coexpression_clusters=GO:0008437!thyrotropin-releasing hormone activity!0.000618156128576475!7200$GO:0007628!adult walking behavior!0.00206052042858825!7200$GO:0009755!hormone-mediated signaling!0.00206052042858825!7200$GO:0008344!adult locomotory behavior!0.00216354645001766!7200$GO:0030534!adult behavior!0.00333804309431296!7200$GO:0005184!neuropeptide hormone activity!0.00339985870717061!7200$GO:0009725!response to hormone stimulus!0.00671140939597315!7200$GO:0007626!locomotory behavior!0.0139857824090427!7200$GO:0005179!hormone activity!0.0144648534086895!7200$GO:0005625!soluble fraction!0.0144648534086895!7200$GO:0007610!behavior!0.0165216274364985!7200$GO:0009719!response to endogenous stimulus!0.0272503826680796!7200$GO:0042221!response to chemical stimulus!0.0280072276716572!7200$GO:0007267!cell-cell signaling!0.0282585658777817!7200$GO:0000267!cell fraction!0.037171788531732!7200$GO:0005102!receptor binding!0.0400642440833628!7200
|id=C430
|id=C430
|ontology_enrichment_celltype=CL:0000763!1.41e-18!112;CL:0000049!1.41e-18!112;CL:0002057!3.03e-18!42;CL:0002009!2.17e-16!65;CL:0002194!2.76e-16!63;CL:0000576!2.76e-16!63;CL:0000040!2.76e-16!63;CL:0000559!2.76e-16!63;CL:0000557!2.87e-16!71;CL:0000860!2.35e-15!45;CL:0000766!2.46e-14!76;CL:0000839!2.81e-14!70;CL:0000037!3.91e-09!172;CL:0000566!3.91e-09!172;CL:0000988!2.33e-08!182;CL:0002032!7.76e-08!165;CL:0000837!7.76e-08!165
|ontology_enrichment_disease=DOID:8692!6.81e-08!31
|ontology_enrichment_uberon=UBERON:0007023!1.82e-23!115;UBERON:0001049!1.01e-17!57;UBERON:0005068!1.01e-17!57;UBERON:0006241!1.01e-17!57;UBERON:0007135!1.01e-17!57;UBERON:0005743!1.08e-15!86;UBERON:0001017!6.82e-15!82;UBERON:0003075!6.89e-15!86;UBERON:0007284!6.89e-15!86;UBERON:0002616!1.52e-14!59;UBERON:0000073!3.27e-14!94;UBERON:0001016!3.27e-14!94;UBERON:0002390!1.18e-13!102;UBERON:0003061!1.18e-13!102;UBERON:0002371!1.25e-13!80;UBERON:0002346!2.83e-13!90;UBERON:0000955!6.78e-13!69;UBERON:0006238!6.78e-13!69;UBERON:0002193!1.42e-12!112;UBERON:0003080!3.46e-12!42;UBERON:0002780!7.28e-12!41;UBERON:0001890!7.28e-12!41;UBERON:0006240!7.28e-12!41;UBERON:0001474!3.12e-11!86;UBERON:0002405!8.14e-10!115;UBERON:0003056!9.61e-10!61;UBERON:0002020!1.13e-09!34;UBERON:0003528!1.13e-09!34;UBERON:0001893!1.32e-09!34;UBERON:0002791!2.56e-09!33;UBERON:0004765!4.57e-09!101;UBERON:0001434!4.57e-09!101;UBERON:0001869!1.75e-08!32;UBERON:0003081!2.84e-07!216;UBERON:0003076!5.94e-07!15;UBERON:0003057!5.94e-07!15;UBERON:0001950!5.95e-07!20;UBERON:0000956!8.98e-07!25;UBERON:0000203!8.98e-07!25
}}
}}

Revision as of 14:47, 21 May 2012


Full id: C430_acute_giant_chronic_CD34_CD133_melanoma_skeletal



Phase1 CAGE Peaks

Hg19::chr11:1918273..1918293,+p@chr11:1918273..1918293
+
Hg19::chr11:1918296..1918324,+p@chr11:1918296..1918324
+
Hg19::chr11:47611749..47611769,-p@chr11:47611749..47611769
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Hg19::chr13:44989025..44989034,-p@chr13:44989025..44989034
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Hg19::chr17:73494329..73494345,+p@chr17:73494329..73494345
+
Hg19::chr19:853278..853299,+p2@ELANE
Hg19::chr19:855662..855672,+p6@ELANE
Hg19::chr19:856037..856044,+p@chr19:856037..856044
+
Hg19::chr19:856109..856117,+p@chr19:856109..856117
+
Hg19::chr1:243432977..243432992,+p@chr1:243432977..243432992
+
Hg19::chr1:243433014..243433053,+p@chr1:243433014..243433053
+
Hg19::chr1:35333189..35333201,-p@chr1:35333189..35333201
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Hg19::chr1:35333224..35333237,-p@chr1:35333224..35333237
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Hg19::chr1:45190613..45190615,-p@chr1:45190613..45190615
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Hg19::chr20:60881426..60881443,+p@chr20:60881426..60881443
+
Hg19::chr20:60881449..60881460,+p@chr20:60881449..60881460
+
Hg19::chr2:127851314..127851361,-p@chr2:127851314..127851361
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Hg19::chr3:129693504..129693519,+p3@TRH
Hg19::chr3:129693523..129693541,+p2@TRH
Hg19::chr7:29900040..29900050,+p@chr7:29900040..29900050
+
Hg19::chr7:29900084..29900122,+p@chr7:29900084..29900122
+
Hg19::chr7:29900130..29900140,+p@chr7:29900130..29900140
+
Hg19::chr8:53062376..53062387,-p@chr8:53062376..53062387
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0008437thyrotropin-releasing hormone activity0.000618156128576475
GO:0007628adult walking behavior0.00206052042858825
GO:0009755hormone-mediated signaling0.00206052042858825
GO:0008344adult locomotory behavior0.00216354645001766
GO:0030534adult behavior0.00333804309431296
GO:0005184neuropeptide hormone activity0.00339985870717061
GO:0009725response to hormone stimulus0.00671140939597315
GO:0007626locomotory behavior0.0139857824090427
GO:0005179hormone activity0.0144648534086895
GO:0005625soluble fraction0.0144648534086895
GO:0007610behavior0.0165216274364985
GO:0009719response to endogenous stimulus0.0272503826680796
GO:0042221response to chemical stimulus0.0280072276716572
GO:0007267cell-cell signaling0.0282585658777817
GO:0000267cell fraction0.037171788531732
GO:0005102receptor binding0.0400642440833628



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>


Uber Anatomy
Ontology termp-valuen
adult organism1.82e-23115
neural tube1.01e-1757
neural rod1.01e-1757
future spinal cord1.01e-1757
neural keel1.01e-1757
central nervous system6.82e-1582
neural plate6.89e-1586
presumptive neural plate6.89e-1586
regional part of brain1.52e-1459
regional part of nervous system3.27e-1494
nervous system3.27e-1494
hematopoietic system1.18e-13102
blood island1.18e-13102
bone marrow1.25e-1380
neurectoderm2.83e-1390
brain6.78e-1369
future brain6.78e-1369
hemolymphoid system1.42e-12112
anterior neural tube3.46e-1242
regional part of forebrain7.28e-1241
forebrain7.28e-1241
future forebrain7.28e-1241
bone element3.12e-1186
immune system8.14e-10115
pre-chordal neural plate9.61e-1061
gray matter1.13e-0934
brain grey matter1.13e-0934
telencephalon1.32e-0934
regional part of telencephalon2.56e-0933
skeletal element4.57e-09101
skeletal system4.57e-09101
cerebral hemisphere1.75e-0832
lateral plate mesoderm2.84e-07216
posterior neural tube5.94e-0715
chordal neural plate5.94e-0715
neocortex5.95e-0720
cerebral cortex8.98e-0725
pallium8.98e-0725
Disease
Ontology termp-valuen
myeloid leukemia6.81e-0831


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.