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Coexpression cluster:C3912

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Full id: C3912_occipital_duodenum_cerebellum_parietal_temporal_middle_hippocampus



Phase1 CAGE Peaks

Hg19::chr1:183310856..183310861,-p@chr1:183310856..183310861
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Hg19::chr2:51208593..51208595,-p@chr2:51208593..51208595
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Hg19::chr8:93036723..93036725,-p@chr8:93036723..93036725
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube9.82e-3557
neural rod9.82e-3557
future spinal cord9.82e-3557
neural keel9.82e-3557
central nervous system2.44e-3282
regional part of nervous system1.89e-3194
nervous system1.89e-3194
brain3.95e-3069
future brain3.95e-3069
regional part of forebrain9.58e-3041
forebrain9.58e-3041
future forebrain9.58e-3041
regional part of brain3.30e-2959
anterior neural tube1.06e-2842
gray matter1.42e-2534
brain grey matter1.42e-2534
telencephalon2.94e-2534
regional part of telencephalon1.98e-2433
neurectoderm4.44e-2490
cerebral hemisphere4.53e-2432
adult organism3.06e-23115
neural plate3.67e-2386
presumptive neural plate3.67e-2386
regional part of cerebral cortex2.88e-2122
cerebral cortex1.75e-1925
pallium1.75e-1925
neocortex3.00e-1920
pre-chordal neural plate8.68e-1961
head3.61e-15123
anterior region of body4.39e-15129
craniocervical region4.39e-15129
ectoderm6.96e-15173
presumptive ectoderm6.96e-15173
ectoderm-derived structure4.54e-14169
temporal lobe4.73e-097
organism subdivision2.37e-08365
basal ganglion3.96e-089
nuclear complex of neuraxis3.96e-089
aggregate regional part of brain3.96e-089
collection of basal ganglia3.96e-089
cerebral subcortex3.96e-089
tube9.83e-08194
nucleus of brain1.61e-079
neural nucleus1.61e-079
posterior neural tube2.20e-0715
chordal neural plate2.20e-0715
gyrus6.56e-076
epithelium9.07e-07309
cell layer9.35e-07312


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

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ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.