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MCL coexpression mm9:2858

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Phase1 CAGE Peaks

 Short description
Mm9::chr13:54691565..54691579,+p2@Higd2a
Mm9::chr4:123395424..123395438,-p1@LOC100504968
p1@Ndufs5
Mm9::chr4:40226422..40226467,-p2@Ndufb6


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0050136NADH dehydrogenase (quinone) activity0.0294905635102609
GO:0003954NADH dehydrogenase activity0.0294905635102609
GO:0008137NADH dehydrogenase (ubiquinone) activity0.0294905635102609
GO:0016655oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor0.0294905635102609
GO:0016651oxidoreductase activity, acting on NADH or NADPH0.0317627684197563



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
nervous system5.33e-2075
central nervous system6.26e-2073
structure with developmental contribution from neural crest1.28e-1992
regional part of nervous system1.00e-1754
neural tube1.53e-1652
neural rod1.53e-1652
future spinal cord1.53e-1652
neural keel1.53e-1652
gray matter5.40e-1634
brain1.09e-1347
future brain1.09e-1347
regional part of brain1.39e-1346
brain grey matter2.13e-1329
regional part of telencephalon2.13e-1329
telencephalon2.13e-1329
ectoderm-derived structure3.44e-1395
ectoderm3.44e-1395
presumptive ectoderm3.44e-1395
neurectoderm6.64e-1364
neural plate6.64e-1364
presumptive neural plate6.64e-1364
anterior neural tube8.68e-1140
regional part of forebrain2.14e-1039
forebrain2.14e-1039
future forebrain2.14e-1039
cerebral cortex1.02e-0921
cerebral hemisphere1.02e-0921
pallium1.02e-0921
ecto-epithelium1.30e-0973
tube1.67e-09114
anatomical conduit4.48e-09122
regional part of cerebral cortex1.27e-0817
primary circulatory organ1.11e-0718
heart1.11e-0718
primitive heart tube1.11e-0718
primary heart field1.11e-0718
anterior lateral plate mesoderm1.11e-0718
heart tube1.11e-0718
heart primordium1.11e-0718
cardiac mesoderm1.11e-0718
cardiogenic plate1.11e-0718
heart rudiment1.11e-0718
pre-chordal neural plate1.28e-0749
compound organ3.17e-0743
posterior neural tube5.64e-0712
chordal neural plate5.64e-0712


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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