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MCL coexpression mm9:2942

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Phase1 CAGE Peaks

 Short description
Mm9::chr14:76362197..76362208,+p@chr14:76362197..76362208
+
Mm9::chr18:62483890..62483902,+p3@Htr4
Mm9::chr4:128798891..128798906,-p6@Hpca


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0004993serotonin receptor activity0.0476529527425605



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
regional part of nervous system1.26e-2254
neural tube1.13e-1952
neural rod1.13e-1952
future spinal cord1.13e-1952
neural keel1.13e-1952
central nervous system2.03e-1973
nervous system1.07e-1875
gray matter1.02e-1734
neurectoderm4.69e-1664
neural plate4.69e-1664
presumptive neural plate4.69e-1664
ectoderm-derived structure3.31e-1495
ectoderm3.31e-1495
presumptive ectoderm3.31e-1495
ecto-epithelium2.94e-1373
spinal cord5.06e-136
dorsal region element5.06e-136
dorsum5.06e-136
brain5.33e-1347
future brain5.33e-1347
regional part of brain6.79e-1246
anterior neural tube3.85e-1140
regional part of spinal cord4.42e-115
gray matter of spinal cord4.42e-115
brain grey matter1.09e-1029
regional part of telencephalon1.09e-1029
telencephalon1.09e-1029
posterior neural tube1.69e-1012
chordal neural plate1.69e-1012
regional part of forebrain6.36e-1039
forebrain6.36e-1039
future forebrain6.36e-1039
pre-chordal neural plate2.17e-0949
structure with developmental contribution from neural crest3.49e-0992
basal ganglion5.34e-098
nuclear complex of neuraxis5.34e-098
aggregate regional part of brain5.34e-098
collection of basal ganglia5.34e-098
cerebral subcortex5.34e-098
regional part of midbrain5.61e-094
midbrain5.61e-094
presumptive midbrain5.61e-094
midbrain neural tube5.61e-094
ventral horn of spinal cord1.56e-073
raphe nuclei1.81e-073
reticular formation1.81e-073
substantia nigra6.50e-073
telencephalic nucleus6.50e-073
midbrain nucleus6.50e-073
neural nucleus6.50e-073
nucleus of brain6.50e-073


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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