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Coexpression cluster:C2723

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Full id: C2723_Pericytes_Meningeal_Smooth_Fibroblast_cerebellum_Hair_rhabdomyosarcoma



Phase1 CAGE Peaks

Hg19::chr3:147111231..147111281,+p3@ZIC1
Hg19::chr3:147111285..147111298,+p10@ZIC1
Hg19::chr3:147111317..147111328,+p8@ZIC1
Hg19::chr3:147131775..147131783,+p@chr3:147131775..147131783
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
central nervous system1.59e-4982
regional part of nervous system2.05e-4894
nervous system2.05e-4894
brain1.29e-4169
future brain1.29e-4169
regional part of brain1.98e-3759
neural tube2.98e-3557
neural rod2.98e-3557
future spinal cord2.98e-3557
neural keel2.98e-3557
ectoderm-derived structure1.87e-28169
neural plate8.63e-2886
presumptive neural plate8.63e-2886
ectoderm5.81e-27173
presumptive ectoderm5.81e-27173
neurectoderm1.88e-2590
regional part of forebrain1.13e-2341
forebrain1.13e-2341
future forebrain1.13e-2341
head3.30e-23123
anterior neural tube9.36e-2342
anterior region of body2.70e-22129
craniocervical region2.70e-22129
pre-chordal neural plate2.43e-2061
telencephalon3.09e-1934
gray matter7.00e-1934
brain grey matter7.00e-1934
regional part of telencephalon1.30e-1833
cerebral hemisphere1.09e-1732
organism subdivision9.15e-15365
adult organism1.90e-14115
posterior neural tube6.33e-1415
chordal neural plate6.33e-1415
cerebral cortex5.04e-1325
pallium5.04e-1325
segmental subdivision of nervous system5.16e-1213
segmental subdivision of hindbrain1.64e-1112
hindbrain1.64e-1112
presumptive hindbrain1.64e-1112
regional part of cerebral cortex2.17e-1122
skin of body4.94e-1140
neocortex4.83e-1020
cell layer3.18e-09312
regional part of metencephalon5.46e-099
metencephalon5.46e-099
future metencephalon5.46e-099
integument9.60e-0945
integumental system9.60e-0945
epithelium3.80e-08309
nucleus of brain1.79e-079
neural nucleus1.79e-079
vasculature of head1.97e-0711
vasculature of organ1.97e-0711
cerebellum2.69e-076
rhombic lip2.69e-076
basal ganglion6.27e-079
nuclear complex of neuraxis6.27e-079
aggregate regional part of brain6.27e-079
collection of basal ganglia6.27e-079
cerebral subcortex6.27e-079


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.